Academic literature on the topic 'In vitro swallowing'

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Journal articles on the topic "In vitro swallowing"

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Patel, Simmi, William J. McAuley, Michael T. Cook, Yi Sun, Shaheen Hamdy, and Fang Liu. "The Swallowing Characteristics of Thickeners, Jellies and Yoghurt Observed Using an In Vitro Model." Dysphagia 35, no. 4 (2019): 685–95. http://dx.doi.org/10.1007/s00455-019-10074-1.

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Abstract Drinks and foods may be thickened to improve swallowing safety for dysphagia patients, but the resultant consistencies are not always palatable. Characterising alternative appetising foods is an important task. The study aims to characterise the in vitro swallowing behaviour of specifically formulated thickened dysphagia fluids containing xanthan gum and/or starch with standard jellies and yoghurt using a validated mechanical model, the “Cambridge Throat”. Observing from the side, the model throat can follow an experimental oral transit time (in vitro-OTT) and a bolus length (BL) at t
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Chakder, S., G. J. Rosenthal, and S. Rattan. "In vivo and in vitro influence of human recombinant hemoglobin on esophageal function." American Journal of Physiology-Gastrointestinal and Liver Physiology 268, no. 3 (1995): G443—G450. http://dx.doi.org/10.1152/ajpgi.1995.268.3.g443.

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The purpose of the present investigation was to examine the influence of a nitric oxide scavenger, hemoglobin (Hb), on esophageal function. Intraluminal pressures of anesthetized opossums were recorded from lower esophageal sphincter (LES) and 1, 5, and 9 cm above the LES. The influence of a representative Hb-based oxygen carrier was examined on swallowing-induced esophageal peristalsis and LES relaxation. In in vitro studies, LES relaxation and esophageal peristaltic contractions were induced by the activation of nonadrenergic noncholinergic (NANC) neurons by electrical field stimulation (EFS
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Malouh, Marwa A., Julie A. Y. Cichero, Yu Sun, Esther T. L. Lau, Lisa M. Nissen, and Kathryn J. Steadman. "Medication Lubricants for Oral Delivery of Drugs: Oral Processing Reduces Thickness, Changes Characteristics, and Improves Dissolution Profile." Pharmaceutics 16, no. 3 (2024): 417. http://dx.doi.org/10.3390/pharmaceutics16030417.

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Swallowing oral solid dosage forms is challenging for those who have medication swallowing difficulties, including patients with dysphagia. One option is to mix the drug (whole or crushed) with a thick vehicle (medication lubricant). Previous in vitro studies consistently suggest that thick vehicles could impact the dissolution of solid dosage forms, potentially influencing their therapeutic effectiveness, but do not account for changes that happen during oral processing and swallowing. This study aims to investigate the potential impact of medication lubricants on drug release and examine the
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Marconati, Marco, and Marco Ramaioli. "The role of extensional rheology in the oral phase of swallowing: an in vitro study." Food & Function 11, no. 5 (2020): 4363–75. http://dx.doi.org/10.1039/c9fo02327e.

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In vitro swallowing experiments suggest that thin, viscoelastic liquids with strong apparent extensional viscosity lead to fast transit, lower oral residues and a compact bolus leaving the oral cavity.
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Fujiso, Yo, Nicolas Perrin, Julian van der Giessen, Nihal Engin Vrana, Fabrice Neveu, and Virginie Woisard. "Swall-E: A robotic in-vitro simulation of human swallowing." PLOS ONE 13, no. 12 (2018): e0208193. http://dx.doi.org/10.1371/journal.pone.0208193.

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Eremin, V. A., and E. V. Blynskaya. "Modern approaches to assessing the quality of orally disintegrating tablets." Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology), no. 6 (December 19, 2023): 8–17. http://dx.doi.org/10.33920/med-13-2306-01.

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Orally disintegrating tablets (ODTs) are the preferred and accepted solid dosage forms by patients. These tablets disintegrate in the oral cavity within a short period, providing an advantage for individuals who have difficulty swallowing. Quality control of ODTs can be achieved through measures such as friability, porosity, hardness, wetting time, water absorption capacity, in vitro disintegration test, and dissolution test. This article summarizes the advantages and in vitro quality control tests of orally disintegrating tablets.
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Tafere, Chernet, Zewdu Yilma, Solomon Abrha, and Adane Yehualaw. "Formulation, in vitro characterization and optimization of taste-masked orally disintegrating co-trimoxazole tablet by direct compression." PLOS ONE 16, no. 3 (2021): e0246648. http://dx.doi.org/10.1371/journal.pone.0246648.

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Introduction Orally disintegrating tablet (ODT) is a dosage form that overcomes the problem of swallowing which is prevalent in about 35% of the general population. Co-trimoxazole (CTX) is given for patients with HIV for the prophylaxis of opportunistic infection (OI), commonly for pneumocystis carinii pneumonia. It was reported that CTX was associated with a 25–46% reduction in mortality among individuals infected with HIV in sub-Saharan Africa. Esophageal candidiasis which usually comes along with HIV/AIDS is one of AIDS defining illness affecting up to 1 in 5 of people with AIDS. This oppor
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Pawar, Harshal Ashok, and Pooja Rasiklal Joshi. "Development and Evaluation of Taste Masked Granular Formulation of Satranidazole by Melt Granulation Technique." Journal of Pharmaceutics 2014 (February 12, 2014): 1–7. http://dx.doi.org/10.1155/2014/789676.

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Drugs from nitroimidazole category are generally bitter in taste. Oral formulation with bitter taste is not palatable. Geriatrics and pediatrics patients usually suffer from swallowing difficulties. Many other patients in some disease conditions avoid swallowing tablets. Satranidazole is a new nitro-imidazole derivative with bitter taste and is available in market as film coated tablet. The purpose of this research was to mask the bitter taste of Satranidazole by coating complexation with low melting point wax and Eudragit EPO. Different types of wax (glyceryl monostearate, stearic acid and ce
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Seifelnasr, Amr, Xiuhua Si, Peng Ding, and Jinxiang Xi. "Liquid Dynamics in the Upper Respiratory–Digestive System with Contracting Pharynx Motions and Varying Epiglottis Angles." Liquids 4, no. 2 (2024): 415–31. http://dx.doi.org/10.3390/liquids4020022.

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Swallowing disorders, or dysphagia, can lead to bolus aspiration in the airway, causing serious adverse health effects. Current clinical interventions for dysphagia are mainly empirical and often based on symptoms rather than etiology, of which a thorough understanding is still lacking. However, it is challenging to study the swallowing process that involves sequential structural motions and is inaccessible to standard visualization instruments. This study proposed an in vitro method to visualize swallowing hydrodynamics and identify the fundamental mechanisms underlying overflow aspirations.
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Kaur, Kiranpreet* and Garg Rajeev. "FAST DISSOLVING TABLET – AN INNOVATIVE APPROACH." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 10 (2018): 10603–11. https://doi.org/10.5281/zenodo.1469989.

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<em>Fast dissolving tablets are the most supportive and widely accepted dosage forms, commonly for pediatric patients. </em><em>Some solid dosage forms like capsules and tablets have issue like worry of swallowing called dysphagia, resulting in matter of patient non-compliance and making the therapy inefficient. FDT disintegrate or dissolve quickly in the saliva in lack of water in within a few seconds (less than 60 seconds) and are real fast dissolving tablets. FDTs are designed to disintegrate speedily, absorb faster so,in vitro drug release time improve and this property of drugs enhanced b
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Dissertations / Theses on the topic "In vitro swallowing"

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Bugarin, Castillo Yurixy. "Évaluation instrumentale et sensorielle des produits alimentaires pour la gestion des troubles salivaires et de la déglutition." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASB023.

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Les troubles de la déglutition sont l'une des principales causes de malnutrition et de déshydratation chez les personnes âgées. Cette étude présente une boîte à outils de méthodes précliniques pour évaluer les produits alimentaires destinés à pallier les symptômes des troubles de la salivation et de la déglutition. Une première illustration de cette approche concerne la conception de substituts salivaires naturels (SSN) et d'aliments semi-liquides à texture adaptée. Différents extraits naturels ont été produits et comparés à la salive humaine en termes de propriétés rhéologiques en cisaillemen
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Book chapters on the topic "In vitro swallowing"

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Qazi, Waqas Muhammad, and Mats Stading. "In Vitro Models for Simulating Swallowing." In Dysphagia. Springer International Publishing, 2017. http://dx.doi.org/10.1007/174_2017_116.

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Conference papers on the topic "In vitro swallowing"

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Akarawita, Isurie, Bangxiang Chen, Jaspreet Dhupia, Weiliang Xu, and Martin Stommel. "A Conceptual Framework for a Real-Time, Deep Learning Model to Estimate In vitro Chewing Cycles Required for Safe Swallowing." In 2024 30th International Conference on Mechatronics and Machine Vision in Practice (M2VIP). IEEE, 2024. http://dx.doi.org/10.1109/m2vip62491.2024.10746125.

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"Challenges of developing a digital twin of an in-vitro device that mimics swallowing." In 25th International Congress on Modelling and Simulation. Modelling and Simulation Society of Australia and New Zealand, 2023. http://dx.doi.org/10.36334/modsim.2023.ghosh146.

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