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Relevant bibliographies by topics / In Vitro Type Drug Release

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Academic literature on the topic 'In Vitro Type Drug Release'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "In Vitro Type Drug Release"

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Begum, M. Yasmin, and Ali Alqahtani. "Characterization of bilayered matrix-type mucoadhesive buccal films containing tizanidine hydrochloride and piroxicam." Tropical Journal of Pharmaceutical Research 20, no. 11 (2021): 2241–48. http://dx.doi.org/10.4314/tjpr.v20i11.1.

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Purpose: To formulate and characterize tizanidine hydrochloride (TZN) and piroxicam (PRX)-loaded bilayer mucoadhesive buccal films with an intention to improve the bioavailability and patient compliance in pain management.Methods: Bilayer buccal films were prepared by solvent evaporation technique using hydroxypropyl methylcellulose (HPMC) 15cps and polyvinylpyrrolidone (PVP K30 as immediate release (IR) layer forming polymers and HPMC K15 M, PVP K 90 along with various muco adhesive polymers (Carbopol P934, sodium alginate, etc), as sustained release (SR) layer forming polymers. The prepared

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Hamdan, Lama, and Jamila Husian. "FORMULATION AND EVALUATION IN VITRO A MATRIX TYPE OF KETOTIFEN FUMARATE TRANSDERMAL PATCHES FOR ALLERGIC DISEASES." Asian Journal of Pharmaceutical and Clinical Research 10, no. 10 (2017): 327. http://dx.doi.org/10.22159/ajpcr.2017.v10i10.20123.

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Objective: Transdermal patches of Ketotifen fumarate (KT) were developed for prolonged effect of the drug, and to protect the patient from allergic symptoms associated with asthma and other allergic diseases.Methods: Matrix type patches were prepared by solvent casting technique using different types of polymers: Hydroxy propyl methyl cellulose (HPMC K15M) and ethyl cellulose to formed the matrix of the patch in different ratios, emulsifying agents were added as a penetration enhancers (Span 60, Tween 60, Cremophor EL) in a ratio 0.025% w/v to the matrix, 10% v/v of glycerin was added as plast

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Tamer, Manar Adnan, Shaimaa Nazar Abd-al Hammid, and Balqis Ahmed. "FORMULATION AND IN VITRO EVALUATION OF BROMOCRIPTINE MESYLATE AS FAST DISSOLVING ORAL FILM." International Journal of Applied Pharmaceutics 10, no. 1 (2018): 7. http://dx.doi.org/10.22159/ijap.2018v10i1.22615.

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Objective: The aim of this study was to formulate and in vitro evaluate fast dissolving oral film of practically insoluble bromocriptine mesylate to enhance its solubility and to improve its oral bioavailability by avoiding first pass effect as well as to produce an immediate release action of the drug from the film for an efficient management of diabetes mellitus type II in addition to an improvement of the patient compliance to this patient-friendly dosage form.Methods: The films were prepared by the solvent casting method using hydroxypropyl methylcellulose of grades (E3, E5, E15), polyviny

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Maver, Uroš, and Tina Maver. "The importance of the correct choice of Franz diffusion cell volume for in vitro drug release testing of wound dressings." Acta Medico-Biotechnica 15, no. 2 (2023): 41–48. http://dx.doi.org/10.18690/actabiomed.241.

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Purpose: Wound dressings are one of the most commonly used products in wound care. Nowadays, various wound dressings are developed containing different active ingredients, often drugs from different pharmacodynamic groups. Considering the variable and changing environment in each wound type, it is important that the experimental design for evaluating the in vitro drug release of such materials takes into account these different conditions. Methods: For this purpose, Franz diffusion cells for in vitro drug release testing are the method of choice, as they are not only able to simulate dif

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Karim, Samira, Mohiuddin Ahmed Bhuiyan, and Md Sohel Rana. "Formulation and in vitro Evaluation of Glimepiride Sustained Release Tablets: Comparison with Immediate Release Tablets." Bangladesh Pharmaceutical Journal 18, no. 2 (2015): 157–62. http://dx.doi.org/10.3329/bpj.v18i2.24315.

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This work aims at the design of a sustained release formulation of glimepiride which is currently available in the treatment of type 2 diabetes mellitus and to investigate the effect of polymers on the release profile of glimepiride. Glimepiride sustained release tablets were prepared by direct compression method using different ratios of various release retarding polymers such as carbopol, ethyl cellulose, methocel K4 MCR, methocel K15 MCR, methocel K100 MCR and xanthum gum. These formulations were also compared with glimepiride immediate release tablets. The prepared tablets were subjected t

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Venkatesh, P., and M. Durga srinivasrao. "FORMULATION AND INVITRO EVALUATION OF PRAZOSIN HYDROCHLORIDE UNFOLDING TYPE GASTRO RETENTIVE FILM." YMER Digital 21, no. 07 (2022): 460–82. http://dx.doi.org/10.37896/ymer21.07/36.

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The present work is based on the formulation and In-vitro evaluation of a gastroretentive mucoadhesvie based drug delivery system containing prazosin hydrochloride for controlled release. It consists of a drug loaded polymeric film folded into a hard gelatin capsule. After administration film unfolds and its swelling and bioadhesion to the gastric mucosa. Prazosin hydrochloride, a histamine H2 receptor antagonist used for gastroesophageal reflux disease (GERD), duodenal ulcer and gastric ulcer. Prazosin hydrochloride absorbed only in the initial part of gastro intestinal tract (GIT) and has le

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Debatri, Roy, Das Sudipta, Panda Madhurima, et al. "Formulation, Evaluation and Release Kinetics of Low Viscosity Metronidazole Gel with Varying Amount o f Carbopol." Indian Journal of Science and Technology 15, no. 48 (2022): 2690–98. https://doi.org/10.17485/IJST/v15i48.2145.

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Abstract <strong>Objective:</strong> The study is centered on formulation and evaluation of low viscosity metronidazole gel with varying amount of Carbopol. <strong>Methods:</strong> Formulations (F1, F2 and F3) of Metronidazole in gel form were done in varying amounts of Carbopol. Prepared gels were inspected for surface pH, viscosity, spreadability, antimicrobial susceptibility, drug content percentage, in vitro process of drug release, release kinetics and stability testing. <strong>Findings:</strong> Formulation pH was placed in between 5 and 6. Measured viscosity

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Ullah, Md Bashir, Md Rezaul Karim, Md Shamsul Alam, Md Rajib Hassan, Mohiuddin Ahmed Bhuiyan, and Md Sohel Rana. "Formulation and In vitro Evaluation of Unfolding Type Expandable Gastroretentive Film of Enalapril Maleate." Bangladesh Pharmaceutical Journal 20, no. 2 (2018): 148–56. http://dx.doi.org/10.3329/bpj.v20i2.37868.

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The present work was based on the development and characterization of unfolding type gastroretentive dosage form appropriate for controlled release of enalapril maleate. Drug loaded films were prepared by solid dispersion technique using methocel K15 and eudragit RSPO and eudragit RLPO as polymers and polyethylene glycol 400 (PEG 400) as the plasticizer. The film folded in a capsule shell was shown to unfold in the gastric juice and provide drug release up to 12 h in the acidic medium. Formulations provided satisfactory unfolding characteristics allowing expansion to remain in the stomach. For

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Đekić, Ljiljana, and Ana Ćirić. "Modeling of in vitro drug release from polymeric microparticle carriers." Arhiv za farmaciju 72, no. 6 (2022): 591–620. http://dx.doi.org/10.5937/arhfarm72-40229.

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Incorporation of active substances in polymeric microparticles (microencapsulation) is an important technological strategy used in the pharmaceutical industry to improve the functionality, quality, safety and/or therapeutic efficiency of pharmaceutical preparations for different routes of administration. The current focus of research in this field is on the encapsulation of small molecules and macromolecules into microparticles based on biocompatible synthetic polymers and biopolymers, such as polypeptides and polysaccharides, in order to achieve preferable drug release kinetics and many other

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Dhulipalla Mounika, I. Deepika Reddy, K. Sai Chandralekha, Kapu Harika, Ramarao Nadendla, and Madhu Gudipati. "Formulation and in-vitro evaluation of ciprofloxacin HCL floating matrix tablets." International Journal of Research in Pharmaceutical Sciences and Technology 2, no. 1 (2020): 01–06. http://dx.doi.org/10.33974/ijrpst.v2i1.221.

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Oral drug delivery is the most widely utilized route of administration among all the routes that have been explored for systemic delivery of drugs via pharmaceutical products of different dosage form. Oral route is considered most natural, uncomplicated, convenient and safe due to its ease of administration, patient acceptance and cost-effective manufacturing process. Gastroretentive drug delivery system was developed in pharmacy field and drug retention for a prolonged time has been achieved. The goal of this study was to formulate and in-vitro evaluate Ciprofloxacin HCl controlled release ma

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Dissertations / Theses on the topic "In Vitro Type Drug Release"

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SMITH, DENISE ANNE BUSH. "In vitro Characterization of Echogenic Liposomes (ELIP) for Ultrasonic Delivery of Recombinant Tissue-type Plasminogen Activator (rt-PA)." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1214234148.

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Graham, M. "Studies on the in-vitro release of salicyclic acid from a polyethylene mineral oil gel." Thesis, De Montfort University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354361.

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Quigley, Karen Josephine. "Factors influencing formation and the in vitro drug release from pellets containing chitosan." Thesis, University College London (University of London), 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266848.

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Tettey-Amlalo, Ralph Nii Okai. "In vitro release of ketoprofen from proprietary and extemporaneously manufactured gels." Thesis, Rhodes University, 2005. http://eprints.ru.ac.za/295/.

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Wang, Hezhong. "Chitosan-Cellulose Nanocrystal Polyelectrolyte Complex Particles: Preparation, Characterization, and In Vitro Drug Release Properties." Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/40353.

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Polyelectrolyte complexes (PECs) between chitosan, a mucoadhesive, intestinal mucosal permeability-enhancing polysaccharide, and cellulose nanocrystals, rod-like cellulose nanoparticles with sulfate groups on their surface, have potential applications in oral drug delivery. The purpose of this research was to develop an understanding of the formation and properties of chitosan–cellulose nanocrystal PECs and determine their in vitro drug release properties, using caffeine and ibuprofen as model drugs. Cellulose nanocrystals were prepared by sulfuric acid hydrolysis of bleached wood pulp. Chitos

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Iyer, Sunil S. "A 'Biorelevant' Approach for Accelerated In Vitro Release and In Vitro-In Vivo Relationship of a Biodegradable, Naltrexone Implant." VCU Scholars Compass, 2006. http://hdl.handle.net/10156/1523.

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Ur-Rehman, Tofeeq. "Controlled release gel formulations and preclinical screening of drug candidates." Doctoral thesis, Umeå universitet, Kemiska institutionen, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-40489.

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Simple gel formulations may be applied to enhance the systemic and local exposure of potential compounds. The aim of this thesis is the development and characterization of controlled release formulations based on thermo-reversible poloxamer gels, which are suitable for novel drug delivery applications. In particular co-solvents (DMSO, ethanol), mucoadhesive polymers (chitosan, alginate) and salts (sodium tripolyphosphate, CaCl2) have been used to enhance the applications of poloxamer 407 (P407) formulations in preclinical animal studies. The impact of these additives on the micellization and

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Chinnakavanam, Sundararaj Sharath Kumar. "Development of a Multilayered Association Polymer System for Sequential Drug Delivery." UKnowledge, 2013. http://uknowledge.uky.edu/cbme_etds/13.

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As all the physiological processes in our body are controlled by multiple biomolecules, comprehensive treatment of certain disease conditions may be more effectively achieved by administration of more than one type of drug. Thus, the primary objective of this research was to develop a multilayered, polymer-based system for sequential delivery of multiple drugs. This particular device was designed aimed at the treatment of periodontitis, a highly prevalent oral inflammatory disease that affects 90% of the world population. This condition is caused by bacterial biofilm on the teeth, resulting in

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ZHOU, YING. "DETERMINATION OF in vitro DRUG RELEASE FROM WOUND DRESSINGS THROUGH AN ARTIFICAL WOUND MODEL." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1018614820.

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Ei, Ei Maw Varaporn Junyaprasert. "Effects of different oil types and surfactant concentrations on the physical stability of nanoemulsions and In Vitro release of Diclofenac-loaded nanoemulsions /." Abstract, 2007. http://mulinet3.li.mahidol.ac.th/thesis/2550/cd406/4837397.pdf.

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Books on the topic "In Vitro Type Drug Release"

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Fotaki, Nikoletta, and Sandra Klein, eds. In Vitro Drug Release Testing of Special Dosage Forms. Wiley, 2019. http://dx.doi.org/10.1002/9781118675748.

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Klein, Sandra, and Nikoletta Fotaki. In Vitro Drug Release Testing of Special Dosage Forms. Wiley & Sons, Incorporated, John, 2019.

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Klein, Sandra, and Nikoletta Fotaki. In Vitro Drug Release Testing of Special Dosage Forms. Wiley & Sons, Incorporated, John, 2019.

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Klein, Sandra, and Nikoletta Fotaki. In Vitro Drug Release Testing of Special Dosage Forms. Wiley & Sons, Limited, John, 2015.

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Klein, Sandra, and Nikoletta Fotaki. In Vitro Drug Release Testing of Special Dosage Forms. Wiley & Sons, Limited, John, 2019.

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Klein, Sandra, and Nikoletta Fotaki. In Vitro Drug Release Testing of Special Dosage Forms. Wiley & Sons, Incorporated, John, 2019.

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universitet, Københavns, ed. Histamine release from basophil leukocytes from HIV infected patients: In vitro studies of type I hypersensitivity reactions to microbial antigens, cytokines, and environmental antigens. 1992.

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Book chapters on the topic "In Vitro Type Drug Release"

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Shah, Vinod P., and Roger L. Williams. "Importance of In Vitro Drug Release." In Topical Drug Bioavailability, Bioequivalence, and Penetration. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1289-6_4.

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Higgins-Gruber, Shannon, Michael J. Rathbone, and Jay C. Brumfield. "In Vitro Drug Release Testing of Veterinary Pharmaceuticals." In Advances in Delivery Science and Technology. Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-4439-8_9.

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Rathbone, Michael J., and James M. Butler. "In Vitro Testing of Controlled Release Dosage Forms During Development and Manufacture." In Controlled Release in Oral Drug Delivery. Springer US, 2011. http://dx.doi.org/10.1007/978-1-4614-1004-1_5.

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Melia, C. D., P. Marshall, P. Stark, S. Cunningham, A. Kinahan, and J. Devane. "Investigating in Vitro Drug Release Mechanisms Inside Dosage Forms." In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4684-6036-0_10.

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Kim, Young Hee, B. G. Song, Soo Ryong Kim, and Kwang Jin Kim. "Drug Loaded Porous Hydroxyapatite and Its In Vitro Release." In Bioceramics 17. Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-961-x.423.

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Judefeind, Anja, and Melgardt M. de Villiers. "Drug Loading into and In Vitro Release from Nanosized Drug Delivery Systems." In Nanotechnology in Drug Delivery. Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-77668-2_5.

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Buckley, Stephen T., Kwang-Jin Kim, and Carsten Ehrhardt. "In Vitro Cell Culture Models for Evaluating Controlled Release Pulmonary Drug Delivery." In Controlled Pulmonary Drug Delivery. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-9745-6_18.

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Guo, Michele Xuemei. "Dissolution Testing: In vitro Characterization of Oral Controlled Release Dosage Forms." In Oral Controlled Release Formulation Design and Drug Delivery. John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470640487.ch15.

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Bhattarai, Rajan S., Virender Kumar, Karthik Nagapudi, Ajit S. Narang, and Ram I. Mahato. "In Vitro Assessment of Drug Release, Dissolution, and Absorption in the Lung." In Organ Specific Drug Delivery and Targeting to the Lungs. CRC Press, 2022. http://dx.doi.org/10.1201/9781003182566-3.

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Shah, Vinod P., and Jerome P. Skelly. "Practical Considerations in Developing a Quality Control (In Vitro Release) Procedure for Topical Drug Products." In Topical Drug Bioavailability, Bioequivalence, and Penetration. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4899-1262-6_5.

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Conference papers on the topic "In Vitro Type Drug Release"

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Park, Juyoung, Murad Melhem, Desai Pankaj, Ronald W. Millard, and Rupak K. Banerjee. "Controlled Drug Releasing Intravitreal Implant Using Biodegradable PLGA." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43136.

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The goal of this work is to compare the in vitro drug (Nimodipine) release rate from three different types (matrix, reservoir, and combination types) of intravitreal implants using a biodegradable polymer (PLGA). The matrix implants were prepared by a solvent cast method and the reservoir implants were fabricated by using a pellet press. The combination implants were a mixed type of matrix and reservoir implants. Each implant was placed in a vial with 7mL of Phosphate Buffered Saline (PBS) containing 0.4 g/L of Bovine Serum Albumin (BSA) and 0.5 mL aliquots were removed for the drug assay for

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Ullah, Aman, Huiqi Wang, and Rehan Pradhan. "Lipid Derived Block Copolymers as Amphiphilic Nanocarriers for Targeted Delivery." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/bfgi9101.

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Amphiphilic thermoresponsive block copolymers and ABA type PEG-Lipid conjugated macromolecules have been synthesized using microwave-assisted reversible addition-fragmentation chain transfer (RAFT) polymerization and the copper-catalyzed azide-alkyne cycloaddition, commonly termed “click chemistry”, respectively. Characterization of the block copolymers and conjugates has been carried out with the help of 1H-NMR, FTIR and GPC. These copolymers and conjugates were evaluated for the encapsulation and release of drugs. Carbamazepine, an anticonvulsant drug with poor water solubility was selected

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Shady, Sally F., and Stephen McCarthy. "Effects of Vinyl Acetate Content and Extrusion Temperatures on Ethylene Vinyl Acetate (EVA) Tetracycline HCL Fibers Used for Periodontal Applications." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-66216.

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Periodontal disease is a prevalent disease that effects all types of ages. Mild cases of periodontal disease include infection and gingivitis. Severe cases of periodontal disease include loss of teeth, and the increased likelihood of systemic diseases such as: cancer, osteoporosis and pneumonia. Current treatments of periodontal disease include systemic approaches such as oral tablets of antibiotics or localized treatments such as the periodontal chip. Oral antibiotics require high dosages to effectively treat the infection therefore causing unwanted side effects. Other treatments include surg

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Al-Ansari, Dana E., Nura A. Mohamed, Isra Marei, Huseyin Yalcin, and Haissam Abou-Saleh. "Assessment of Metal Organic Framework as Potential Drug Carriers in Cardiovascular Diseases." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0127.

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Background: Cardiovascular diseases (CVDs) are considered the major cause of death worldwide. Therapeutic delivery to the cardiovascular system may play an important role in the successful treatment of a variety of CVDs, including atherosclerosis, ischemic-reperfusion injury, and microvascular diseases. Despite their clinical benefits, current therapeutic drugs are hindered by their short half-life and systemic side effects. This limitation could be overcome using controlled drug release with the potential for targeted drug delivery using a nanomedicine approach. In the current study, we have

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Lim, Mim Mim, and Naznin Sultana. "Drug loading, drug release and in vitro degradation of poly(caprolactone) electrospun fibers." In 2014 IEEE Conference on Biomedical Engineering and Sciences (IECBES). IEEE, 2014. http://dx.doi.org/10.1109/iecbes.2014.7047520.

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Al-Tememe, E. H., Fatima H. Malk, and Rawaa M. O. Hraishawi. "Synthesis, characterization and in vitro drug release studies of polymeric drug coated zinc oxide nanoparticles." In 2ND INTERNATIONAL CONFERENCE ON ENGINEERING & SCIENCE. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0069882.

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Berchane, Nader S., Kenneth H. Carson, Allison C. Rice-Ficht, and Malcolm J. Andrews. "Investigation of Drug Release From Biodegradable PLG Microspheres: Experiment and Theory." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176030.

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Piroxicam containing PLG microspheres having different size distributions were fabricated, and in vitro release kinetics were determined for each preparation. Based on the experimental results, a suitable mathematical theory has been developed that incorporates the effect of microsphere size distribution and polymer degradation on drug release. We show from in vitro release experiments that microsphere size has a significant effect on drug release rate. The initial release rate decreased with an increase in microsphere size. In addition, the release profile changed from first order to concave-

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Maloney, John M. "An Implantable Microfabricated Drug Delivery System." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43186.

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We report on the development of a fully implantable drug delivery system capable of delivering hundreds of individual doses. This product is intended for the controlled release of potent therapeutic compounds that might otherwise require frequent injections. Our system has the following capabilities: • Stable, hermetic storage of therapeutic drugs in solid, liquid, or gel form; • Individual storage of discrete doses for multiple-drug regimens; • Wireless communication with an external controller for device monitoring and therapy modification; • Choice of preprogrammed release or release on com

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Zhang, Xueqiong, Hua Zheng, Bo Lu, and Fuliang Xiong. "Preparation, Characterization and Drug Release in Vitro of Galactosylated Chitosan-Graft-PEG Nanoparticles." In 2010 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2010. http://dx.doi.org/10.1109/icbbe.2010.5516538.

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Buyukhatipoglu, Kivilcim, Tiffany A. Miller, and Alisa Morss Clyne. "Biocompatible, Superparamagnetic, Flame Synthesized Iron Oxide Nanoparticles: Cellular Uptake and Toxicity Studies." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-68049.

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Superparamagnetic iron oxide nanoparticles, including magnetite (Fe3O4), are widely used in applications such as targeted drug delivery, magnetic resonance imaging, tissue engineering, gene therapy, hyperthermic malignant cell treatment, and cell membrane manipulation. These nanoparticles are particularly interesting for in vivo and in vitro applications since they do not exhibit magnetic behavior once the magnetic field has been removed. In the current work, superparamagnetic iron oxide nanoparticles were produced using a flame synthesis method, which provides significant advantages over othe

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Reports on the topic "In Vitro Type Drug Release"

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Chutimaworapan, Suchada, Chaiyo Chaichantippayuth, and Areerat Laopaksa. Formulation of pharmaceutical products of Garcinia mangostana Linn. extracts. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.32.

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Part I: The purpose of the investigation was to develop the extraction process that was simple, practical and giving high yield. The maceration of dried powder of Garcinia mangostana fruit husk with ethyl acetate gave yellow crystalline powder of mangostin. The yield was calculated as 7.47%. The identification of the Garcinia mangostanahusk extract was carried out by thin-layer chromatography (TLC) and differential scanning calorimetry. The TLC of mangostin was done by using the alumina sheet and ethyl acetate: hexane (3:1) as mobile phase. The Rf value as compared with standard mangostin was

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Hawkins, Brian T., and Sonia Grego. A Better, Faster Road From Biological Data to Human Health: A Systems Biology Approach for Engineered Cell Cultures. RTI Press, 2017. http://dx.doi.org/10.3768/rtipress.2017.rb.0015.1706.

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Traditionally, the interactions of drugs and toxicants with human tissue have been investigated in a reductionist way—for example, by focusing on specific molecular targets and using single-cell-type cultures before testing compounds in whole organisms. More recently, “systems biology” approaches attempt to enhance the predictive value of in vitro biological data by adopting a comprehensive description of biological systems and using computational tools that are sophisticated enough to handle the complexity of these systems. However, the utility of computational models resulting from these eff

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Ruxrungtham, Kiat, Vorapot Sapsirisavat, Vorasit Vongsutilers, et al. Pharmaceutical equivalence drugs assessment-I (PEDA-I) : assess the pharmaceutical equivalence of generic antiretrovirals distributed in Thailand : Final report. Chulalongkorn University, 2016. https://doi.org/10.58837/chula.res.2016.30.

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Objectives: Ensuring that medicines meet quality standards is mandatory for ensuring safety and efficacy. There have been occasional reports of substandard generic medicines, especially in resource-limiting settings where policies to control quality may be less rigorous. As HIV treatment in Thailand depends mostly on affordable generic antiretrovirals (ARV), we performed quality assurance testing of several generic ARV available from different sources in Thailand and a source from Vietnam. Methods: We sampled Tenofovir 300 mg, Efavirenz 600 mg and Lopinavir/ritonavir 200/50mg from 10 primary h

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Meidan, Rina, and Robert Milvae. Regulation of Bovine Corpus Luteum Function. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604935.bard.

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The main goal of this research plan was to elucidate regulatory mechanisms controlling the development, function of the bovine corpus luteum (CL). The CL contains two different sterodigenic cell types and therefore it was necessary to obtain pure cell population. A system was developed in which granulosa and theca interna cells, isolated from a preovulatory follicle, acquired characteristics typical of large (LL) and small (SL) luteal cells, respectively, as judged by several biochemical and morphological criteria. Experiments were conducted to determine the effects of granulosa cells removal

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