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Journal articles on the topic 'In-vivo diagnostics'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

Slomovic, Shimyn, Keith Pardee, and James J. Collins. "Synthetic biology devices for in vitro and in vivo diagnostics." Proceedings of the National Academy of Sciences 112, no. 47 (2015): 14429–35. http://dx.doi.org/10.1073/pnas.1508521112.

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There is a growing need to enhance our capabilities in medical and environmental diagnostics. Synthetic biologists have begun to focus their biomolecular engineering approaches toward this goal, offering promising results that could lead to the development of new classes of inexpensive, rapidly deployable diagnostics. Many conventional diagnostics rely on antibody-based platforms that, although exquisitely sensitive, are slow and costly to generate and cannot readily confront rapidly emerging pathogens or be applied to orphan diseases. Synthetic biology, with its rational and short design-to-p

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2

Fésűs, Luca. "Innovative in vivo imaging techniques in dermatology." Bőrgyógyászati és Venerológiai Szemle 98, no. 3 (2022): 133–41. http://dx.doi.org/10.7188/bvsz.2022.98.3.5.

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As a result of advances in the development of medical imaging, the toolbox of dermatological imaging in the XXI. century expanded considerably. In addition to the histological examination that is currently the gold standard in diagnostics, a number of noninvasive imaging methods have emerged in recent decades that have become part of the clinical and preclinical practice. The characteristics of many dermatological diseases have been described in vivo studies with commercially available devices. The authors summarize the principles of terahertz imaging, photoacoustic imaging, reflectance and au

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3

Rahman, Muhammad, Meisam Nazari, Mehmet Sencan, Samson Chen, Xio Madera, and Axel Scherer. "WIRELESS HEALTH SENSORS FOR IN VIVO DIAGNOSTICS." Technology & Innovation 17, no. 4 (2016): 177–86. http://dx.doi.org/10.3727/194982416x14520374942988.

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4

Djokic, Divna. "Technetium-99m radiopharmaceuticals for in vivo diagnostics." Medical review 58, no. 3-4 (2005): 180–84. http://dx.doi.org/10.2298/mpns0504180d.

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Technetiiim-99m is an ideal radionuclide with optimum decay characteristics. It can be obtained in sterile, pyrogen-free and carrier-free condition, as sodium pertechnetate (Na99mTcO4), from 99Mo/99Tc generator. Because of its six-hour physical half-life and monochromatic 140 keV photons free of -radiation, administration of small amounts of 99mTc solution is possible, without a significant radiation damage to the patient. Technetium eluted from the 99Mo/99mTc generator is in the highest oxidation form (+7). It can be used for diagnostic purposes alone, but it is often used for labeling differ

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5

Frangioni, John V. "Translating in vivo diagnostics into clinical reality." Nature Biotechnology 24, no. 8 (2006): 909–13. http://dx.doi.org/10.1038/nbt0806-909.

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6

Helm, Ricki M. "Food allergy: in-vivo diagnostics including challenge." Current Opinion in Allergy and Clinical Immunology 1, no. 3 (2001): 255–59. http://dx.doi.org/10.1097/01.all.0000011023.54760.d3.

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7

Hernychová, Lenka, Dominika Coufalová, Eva Michalová, Rudolf Nenutil, and Bořivoj Vojtěšek. "New Technologies for In Vivo Cancer Diagnostics." Klinicka onkologie 29, Suppl 4 (2016): 4S88–4S94. http://dx.doi.org/10.14735/amko20164s88.

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8

Helm, Ricki M. "Food allergy: in-vivo diagnostics including challenge." Current Opinion in Allergy and Clinical Immunology 1, no. 3 (2001): 255–59. http://dx.doi.org/10.1097/00130832-200106000-00010.

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9

Edem, Patricia E., Jesper Fonslet, Andreas Kjær, Matthias Herth, and Gregory Severin. "In Vivo Radionuclide Generators for Diagnostics and Therapy." Bioinorganic Chemistry and Applications 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/6148357.

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In vivo radionuclide generators make complex combinations of physical and chemical properties available for medical diagnostics and therapy. Perhaps the best-known in vivo generator is 212Pb/212Bi, which takes advantage of the extended half-life of 212Pb to execute a targeted delivery of the therapeutic short-lived α-emitter 212Bi. Often, as in the case of 81Rb/81Kr, chemical changes resulting from the transmutation of the parent are relied upon for diagnostic value. In other instances such as with extended alpha decay chains, chemical changes may lead to unwanted consequences. This article re

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10

Lee, Dong Soo, and Gi Jeong Cheon. "Nuclear Theranostics in Asia: In vivo Companion Diagnostics." Nuclear Medicine and Molecular Imaging 53, no. 1 (2019): 1–6. http://dx.doi.org/10.1007/s13139-019-00573-2.

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11

Omstead, David T., Jenna Sjoerdsma, and Basar Bilgicer. "Polyvalent Nanoobjects for Precision Diagnostics." Annual Review of Analytical Chemistry 12, no. 1 (2019): 69–88. http://dx.doi.org/10.1146/annurev-anchem-061318-114938.

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As our ability to synthesize and modify nanoobjects has improved, efforts to explore nanotechnology for diagnostic purposes have gained momentum. The variety of nanoobjects, especially those with polyvalent properties, displays a wide range of practical and unique properties well suited for applications in various diagnostics. This review briefly covers the broad scope of multivalent nanoobjects and their use in diagnostics, ranging from ex vivo assays and biosensors to in vivo imaging. The nanoobjects discussed here include silica nanoparticles, gold nanoparticles, quantum dots, carbon dots,

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Myronova, O. V., G. O. Romanenko, A. H. Mazur, N. V. Goryainova, and A. V. Makarenko. "PERFORMANCE OF DIFFERENTIAL DIAGNOSTICS OF FOCAL LESIONS OF THE LIVER USING RADIONUCLIDE METHODS �IN VIVO� AND �IN VITRO�." HEMATOLOGY AND BLOOD TRANSFUSION: INTERDEPARTAMENTAL COLLECTION, no. 42 (2023): 188–205. http://dx.doi.org/10.33741/0435-1991.42.15.

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13

Di Staso, Federico, Daria Rullo, Mariachiara Di Pippo, Silvio Di Staso, and Solmaz Abdolrahimzadeh. "Optical Diagnostics in Herpetic Keratitis." Photonics 10, no. 4 (2023): 349. http://dx.doi.org/10.3390/photonics10040349.

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One of the leading global causes of vision impairment due to anterior segment disease is herpes simplex keratitis (HSK). The routine clinical method in the diagnosis of HSK is examination of the eye using slit lamp biomicroscopy; nevertheless, this is a subjective examination and can potentially lead to an erroneous diagnosis. Optical devices such as in vivo confocal microscopy and anterior segment optical coherence tomography are among the additional diagnostic tools that provide a valuable resource in the diagnosis and management of the condition. In research settings, these technologies hav

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14

Tikhonova, E. V., S. N. Berdnikov, I. V. Samoylenko, et al. "Comparison of in vivo and ex vivo Elastography and Elastometric in the Diagnosis of Metastasis of Skin Melanoma to Peripheral Lymph Nodes." Journal of oncology: diagnostic radiology and radiotherapy 8, no. 2 (2025): 65–72. https://doi.org/10.37174/2587-7593-2025-8-2-65-72.

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Purpose: To conduct a comparative analysis of the diagnostic effectiveness of elastography and elastometry in detecting melanoma metastases in lymph nodes using histological examination of a macropreparation as a reference method. The data obtained can help in the development of algorithms for noninvasive diagnostics and reduce the number of unjustified surgical interventions. Materials and methods: A prospective study of 14 macro-preparations of metastatically affected lymph nodes removed from patients with skin melanoma during elective surgical interventions was conducted. Conclusion: An int

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15

Philippidis, Alex. "Mammoth Valuation: Unicorn Pursues In Vivo CRISPR Drugs, Diagnostics." GEN Edge 3, no. 1 (2021): 545–51. http://dx.doi.org/10.1089/genedge.3.1.090.

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16

Tuan Vo-Dihn, D. L. Stokes, M. B. Wabuyele, et al. "A hyperspectral imaging system for in vivo optical diagnostics." IEEE Engineering in Medicine and Biology Magazine 23, no. 5 (2004): 40–49. http://dx.doi.org/10.1109/memb.2004.1360407.

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17

Hogg, Tad, and Philip J. Kuekes. "Mobile microscopic sensors for high resolution in vivo diagnostics." Nanomedicine: Nanotechnology, Biology and Medicine 2, no. 4 (2006): 239–47. http://dx.doi.org/10.1016/j.nano.2006.10.004.

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18

Hogg, Tad Henry. "Mobile Microscopic Sensors for High-Resolution in vivo Diagnostics." Nanomedicine: Nanotechnology, Biology and Medicine 2, no. 4 (2006): 288–89. http://dx.doi.org/10.1016/j.nano.2006.10.067.

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19

Yanina, Irina Yu, Vadim D. Genin, Elina A. Genina, et al. "Multimodal Diagnostics of Changes in Rat Lungs after Vaping." Diagnostics 13, no. 21 (2023): 3340. http://dx.doi.org/10.3390/diagnostics13213340.

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(1) Background: The use of electronic cigarettes has become widespread in recent years. The use of e-cigarettes leads to milder pathological conditions compared to traditional cigarette smoking. Nevertheless, e-liquid vaping can cause morphological changes in lung tissue, which affects and impairs gas exchange. This work studied the changes in morphological and optical properties of lung tissue under the action of an e-liquid aerosol. To do this, we implemented the “passive smoking” model and created the specified concentration of aerosol of the glycerol/propylene glycol mixture in the chamber

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20

Kim, Moon Jong. "Tracing Quiescent Cancer Cells In Vivo." Cancers 16, no. 22 (2024): 3822. http://dx.doi.org/10.3390/cancers16223822.

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QCCs have long gained significant interest as potential “seeds” for recurrent cancers. Clinical evidence suggests that a subset of cancer cells exits the cell cycle and enters a quiescent state following anti-cancer treatment. These microscopic-residual QCCs are extremely challenging to trace and detect within patients. Additionally, QCCs resist conventional anti-cancer therapies due to the lack of cell activity. Notably, upon the unknown environmental cues in unknown time points, sometimes decades later, QCCs can reactivate, triggering cancer relapse at primary or secondary sites. Currently,

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21

Wang, Bang, Firas Kobeissy, Mojtaba Golpich, et al. "Aptamer Technologies in Neuroscience, Neuro-Diagnostics and Neuro-Medicine Development." Molecules 29, no. 5 (2024): 1124. http://dx.doi.org/10.3390/molecules29051124.

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Aptamers developed using in vitro Systematic Evolution of Ligands by Exponential Enrichment (SELEX) technology are single-stranded nucleic acids 10–100 nucleotides in length. Their targets, often with specificity and high affinity, range from ions and small molecules to proteins and other biological molecules as well as larger systems, including cells, tissues, and animals. Aptamers often rival conventional antibodies with improved performance, due to aptamers’ unique biophysical and biochemical properties, including small size, synthetic accessibility, facile modification, low production cost

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22

Jain, Kewal K. "Applications of Nanobiotechnology in Clinical Diagnostics." Clinical Chemistry 53, no. 11 (2007): 2002–9. http://dx.doi.org/10.1373/clinchem.2007.090795.

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Abstract Background: Nanobiotechnologies are being applied to molecular diagnostics and several technologies are in development. Methods: This review describes nanobiotechnologies that are already incorporated in molecular diagnostics or have potential applications in clinical diagnosis. Selected promising technologies from published literature as well as some technologies that are in commercial development but have not been reported are included. Results: Nanotechnologies enable diagnosis at the single-cell and molecule levels, and some can be incorporated in current molecular diagnostic meth

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23

Michalet, X. "Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics." Science 307, no. 5709 (2005): 538–44. http://dx.doi.org/10.1126/science.1104274.

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24

Kairdolf, Brad A., Ximei Qian, and Shuming Nie. "Bioconjugated Nanoparticles for Biosensing, in Vivo Imaging, and Medical Diagnostics." Analytical Chemistry 89, no. 2 (2017): 1015–31. http://dx.doi.org/10.1021/acs.analchem.6b04873.

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25

Scoggin, Kirsten E., Brad R. Borlee, Carleigh E. Fedorka, and Mats HT Troedsson. "Identification of endometrial biofilm-specific proteins for in vivo diagnostics." Journal of Equine Veterinary Science 125 (June 2023): 104743. http://dx.doi.org/10.1016/j.jevs.2023.104743.

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26

Krohne, Ingo. "Faseroptische konfokale Mikroendoskopie für die In-vivo-Diagnostik (Fiber-Optical Confocal Microendoscopy for in-vivo Diagnostics)." tm - Technisches Messen 71, no. 7-8-2004 (2004): 427–34. http://dx.doi.org/10.1524/teme.71.7.427.36687.

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27

Xing, Yun, and Jianghong Rao. "Quantum dot bioconjugates for in vitro diagnostics & in vivo imaging." Cancer Biomarkers 4, no. 6 (2008): 307–19. http://dx.doi.org/10.3233/cbm-2008-4603.

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28

Kuntic, Vesna, Jasmina Brboric, Zorica Vujic, and Snezana Uskokovic-Markovic. "Radioisotopes Used as Radiotracers for in vitro and in vivo Diagnostics." Asian Journal of Chemistry 28, no. 2 (2016): 235–41. http://dx.doi.org/10.14233/ajchem.2016.19401.

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29

Rybyanets A. N., Shvetsov I. A., Shvetsova N. A., Reznichenko A. N., and Kolpacheva N. A. "Bioimpedance analysis of the patient's superficial tissues." Technical Physics Letters 48, no. 8 (2022): 22. http://dx.doi.org/10.21883/tpl.2022.08.55054.19158.

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A new method for analyzing physiological conditions of the patient's superficial tissues in vivo is proposed. Precision measurements of the complex electrical resistance were performed using the bioimpedance spectroscopy method. The design of a diagnostic module for complex non-invasive diagnostics of the physiological condition and processes in the surface tissues of a patient has been developed. An experimental verification of the developed method of bioimpedance spectroscopy was carried out on reference solutions and patient's superficial tissues in vivo. A biophysical interpretation of the

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30

Wang, Yu-jing, and Min Ke. "Meibomian Glands or Not? Identification of In Vivo and Ex Vivo Confocal Microscopy Features and Histological Correlates in the Eyelid Margin." Journal of Ophthalmology 2020 (June 30, 2020): 1–8. http://dx.doi.org/10.1155/2020/7516286.

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Purpose. In vivo confocal laser scanning microscopy (CLSM) is an emerging diagnostic tool allowing fast and easy microscopic tissue examination. For the diagnostics of pathological eyelid margin lesions, the knowledge of the normal eyelid margin is essential. Methods. We examined 18 eyelid margins of healthy humans using the in vivo CLSM device and 10 samples of healthy eyelid margins from donor sites with ex vivo CLSM and compared the findings to the corresponding histological sections of donor sites. Cross-section images of different depths and depths of different skin appendages were measur

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31

Kubanov, A. A., J. A. Galljamova, A. S. Grevtseva, and N. V. Gribanov. "Modern demodicosis diagnostics methods." Vestnik dermatologii i venerologii 92, no. 1 (2016): 47–54. http://dx.doi.org/10.25208/0042-4609-2016-92-1-47-54.

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An overview of the modern demodicosis diagnostics methods and in-house demodicosis diagnosis with intravital laser scanning confocal microscopy effectiveness studies. The study included 60 patients with acne and rosacea, complicated demodicosis, 60 patients with acne and rosacea and no demodicosis, and 30 healthy volunteers. All the patients underwent skin scraping, eyebrows and/or eyelashes hair removal and confocal laser-scanning microscopy. the advantages of confocal laser-scanning microscopy in vivo in comparison with conventional methods of research are shown.

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32

Kubanova, A. A., V. V. Chikin, YU YU Shtirshneider, and O. R. Katunina. "Confocal laser scanning microscopy in vivo for diagnosing melanocytic skin neoplasms." Vestnik dermatologii i venerologii 90, no. 3 (2014): 85–94. http://dx.doi.org/10.25208/0042-4609-2014-90-3-85-94.

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The authors discuss the use of confocal laser scanning microscopy in vivo (CLSM) for diagnosing melanocytic skin neoplasms and its value for early diagnostics of melanoma. CLSM is an innovation noninvasive visual examination method for real-time multiple and painless examinations of the patient’s skin without injuring the skin integument. The method ensures early diagnostics of skin melanomas with high sensitivity and specificity, which makes it possible to use CLSM for screening melanocytic skin neoplasms for the sake of the early onset of treatment to save patient life and health.

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33

Shvetsov I. A., Shvetsova N. A., Kolpacheva N. A., and Rybyanets A. N. "Ultrasound diagnostics of the patient's surperficial tissues." Technical Physics Letters 48, no. 10 (2022): 49. http://dx.doi.org/10.21883/tpl.2022.10.54799.19172.

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A new method of ultrasonic examination of the superficial tissues of a patient in vivo has been proposed. The design of ultrasonic measuring module for complex non-invasive diagnostics of the physiological conditions and processes in the superficial tissues of a patient has been developed. Precise measurements of the speed and attenuation of ultrasonic waves were made using the echo-pulse and transmission methods. An experimental verification of the developed ultrasonic method was carried out on reference solutions and superficial tissues of the patient. Keywords: ultrasound diagnostics, echo-

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34

Biela-Mazur, Jadwiga, Anna Czyżewska-Dudek, and Paulina Jazgarska. "Use of in vitro and in vivo tests in the diagnosis of food-induced anaphylaxis – a case study." Pediatria i Medycyna Rodzinna 19, no. 4 (2023): 419–24. http://dx.doi.org/10.15557/pimr.2023.0064.

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Food allergy is a chronic disease that affects both children and adults. Systemic allergic reactions in children are most commonly caused by foods, especially nuts, milk, and eggs. A conventional diagnostic work-up for allergy typically pinpoints the allergen source, while component-resolved diagnostics is an approach that identifies the allergen molecules responsible for causing anaphylaxis. In some cases, determining the causative agent of anaphylaxis requires the use of various diagnostic tests. In the following paper, we want to highlight the importance of a critical approach to allergy te

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35

Hillmann, Dierck, Hendrik Spahr, Clara Pfäffle, Helge Sudkamp, Gesa Franke, and Gereon Hüttmann. "In vivo optical imaging of physiological responses to photostimulation in human photoreceptors." Proceedings of the National Academy of Sciences 113, no. 46 (2016): 13138–43. http://dx.doi.org/10.1073/pnas.1606428113.

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Noninvasive functional imaging of molecular and cellular processes of vision may have immense impact on research and clinical diagnostics. Although suitable intrinsic optical signals (IOSs) have been observed ex vivo and in immobilized animals in vivo, detecting IOSs of photoreceptor activity in living humans was cumbersome and time consuming. Here, we observed clear spatially and temporally resolved changes in the optical path length of the photoreceptor outer segment as a response to an optical stimulus in the living human eye. To witness these changes, we evaluated phase data obtained with

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36

Lippi, Giuseppe, and Mario Plebani. "Integrated diagnostics." Biochemia medica 30, no. 1 (2020): 18–30. http://dx.doi.org/10.11613/bm.2020.010501.

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The current scenario of in vitro and in vivo diagnostics can be summarized using the “silo metaphor”, where laboratory medicine, pathology and radiology are three conceptually separated diagnostic disciplines, which will increasingly share many comparable features. The substantial progresses in our understanding of biochemical-biological interplays that characterize many human diseases, coupled with extraordinary technical advances, are now generating important multidisciplinary convergences, leading the way to a new frontier, called integrated diagnostics. This new discipline, which is curren

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37

Рыбянец, А. Н., И. А. Швецов, Н. А. Швецова, А. Н. Резниченко та Н. А. Колпачева. "Биоимпедансный анализ состояния поверхностных тканей пациента". Письма в журнал технической физики 48, № 15 (2022): 26. http://dx.doi.org/10.21883/pjtf.2022.15.53128.19158.

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A new method for analyzing physiological conditions of the patient's superficial tissues in vivo is proposed. Precision measurements of the complex electrical resistance were performed using the bioimpedance spectroscopy method. The design of a diagnostic module for complex non-invasive diagnostics of the physiological condition and processes in the surface tissues of a patient has been developed. An experimental verification of the developed method of bioimpedance spectroscopy was carried out on reference solutions and patient's superficial tissues in-vivo. A biophysical interpretation of the

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38

Швецов, И. А., Н. А. Швецова, Н. А. Колпачева та А. Н. Рыбянец. "Ультразвуковая диагностика состояния поверхностных тканей пациента". Письма в журнал технической физики 48, № 20 (2022): 11. http://dx.doi.org/10.21883/pjtf.2022.20.53689.19172.

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A new method for analyzing physiological conditions of the patient's superficial tissues in vivo is proposed. Precision measurements of the complex electrical resistance were performed using the bioimpedance spectroscopy method. The design of a diagnostic module for complex non-invasive diagnostics of the physiological condition and processes in the surface tissues of a patient has been developed. An experimental verification of the developed method of bioimpedance spectroscopy was carried out on reference solutions and patient's superficial tissues in-vivo. A biophysical interpretation of the

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39

Ly, Suw Young, and Chang Hyun Lee. "Brain computer interfaced neuro-intelligence feeling sensing via In-Vivo diagnostics." KOREA SCIENCE & ART FORUM 26 (December 31, 2016): 281. http://dx.doi.org/10.17548/ksaf.2016.12.26.281.

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40

VanSchoiack, Lindsey R., Veronica I. Shubayev, Robert R. Myers, Cherilyn G. Sheets, and James C. Earthman. "In Vivo Evaluation of Quantitative Percussion Diagnostics for Determining Implant Stability." International Journal of Oral & Maxillofacial Implants 28, no. 5 (2013): 1286–92. http://dx.doi.org/10.11607/jomi.2779.

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41

Henry, Anne-Isabelle, Bhavya Sharma, M. Fernanda Cardinal, Dmitry Kurouski, and Richard P. Van Duyne. "Surface-Enhanced Raman Spectroscopy Biosensing: In Vivo Diagnostics and Multimodal Imaging." Analytical Chemistry 88, no. 13 (2016): 6638–47. http://dx.doi.org/10.1021/acs.analchem.6b01597.

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42

Rudeschko, O., B. Fahlbusch, M. Henzgen, G. Schlenvoigt, D. Herrmann, and L. Jäger. "Optimization of apple allergen preparation for in vivo and in vitro diagnostics." Allergy 50, no. 3 (1995): 262–68. http://dx.doi.org/10.1111/j.1398-9995.1995.tb01144.x.

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43

Imyanitov, Evgeny N. "Molecular diagnostics in oncology: new trends." Medical academic journal 19, no. 4 (2020): 25–32. http://dx.doi.org/10.17816/maj19281.

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Molecular diagnostics is a mandatory component of modern clinical oncology. The most known examples of molecular diagnostic procedures include the detection of hereditary cancer syndromes and the analysis of somatic drug-sensitizing mutations in protein kinases. Advances in cancer research as well as the development of new technologies led to emergence of new trends in this area of medicine. The invention of next generation sequencing (NGS) has a potential to dramatically change the landscape of molecular diagnostics. NGS allows to significantly improve the efficiency and availability of genet

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44

Farrakhova, Dina, Igor Romanishkin, Yuliya Maklygina, Lina Bezdetnaya, and Victor Loschenov. "Analysis of Fluorescence Decay Kinetics of Indocyanine Green Monomers and Aggregates in Brain Tumor Model In Vivo." Nanomaterials 11, no. 12 (2021): 3185. http://dx.doi.org/10.3390/nano11123185.

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Spectroscopic approach with fluorescence time resolution allows one to determine the state of a brain tumor and its microenvironment via changes in the fluorescent dye’s fluorescence lifetime. Indocyanine green (ICG) is an acknowledged infra-red fluorescent dye that self-assembles into stable aggregate forms (ICG NPs). ICG NPs aggregates have a tendency to accumulate in the tumor with a maximum accumulation at 24 h after systemic administration, enabling extended intraoperative diagnostic. Fluorescence lifetime analysis of ICG and ICG NPs demonstrates different values for ICG monomers and H-ag

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45

Farooq, Afifa, Shafiya Sabah, Salam Dhou, Nour Alsawaftah, and Ghaleb Husseini. "Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging." Nanomaterials 12, no. 3 (2022): 393. http://dx.doi.org/10.3390/nano12030393.

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The field of cancer theranostics has grown rapidly in the past decade and innovative ‘biosmart’ theranostic materials are being synthesized and studied to combat the fast growth of cancer metastases. While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. Therefore, improved diagnostics are needed to define in vivo tumor growths on a molecular level to achieve image-guided therapies and tailored dosage needs. This review summarizes in vivo studies that utilize contrast agents within the field

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46

Quarta, Alessandra, Clara Piccirillo, Giacomo Mandriota, and Riccardo Di Corato. "Nanoheterostructures (NHS) and Their Applications in Nanomedicine: Focusing on In Vivo Studies." Materials 12, no. 1 (2019): 139. http://dx.doi.org/10.3390/ma12010139.

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Inorganic nanoparticles have great potential for application in many fields, including nanomedicine. Within this class of materials, inorganic nanoheterostructures (NHS) look particularly promising as they can be formulated as the combination of different domains; this can lead to nanosystems with different functional properties, which, therefore, can perform different functions at the same time. This review reports on the latest development in the synthesis of advanced NHS for biomedicine and on the tests of their functional properties in in vivo studies. The literature discussed here focuses

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47

Altangerel, Narangerel, Gombojav O. Ariunbold, Connor Gorman, et al. "In vivo diagnostics of early abiotic plant stress response via Raman spectroscopy." Proceedings of the National Academy of Sciences 114, no. 13 (2017): 3393–96. http://dx.doi.org/10.1073/pnas.1701328114.

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Development of a phenotyping platform capable of noninvasive biochemical sensing could offer researchers, breeders, and producers a tool for precise response detection. In particular, the ability to measure plant stress in vivo responses is becoming increasingly important. In this work, a Raman spectroscopic technique is developed for high-throughput stress phenotyping of plants. We show the early (within 48 h) in vivo detection of plant stress responses. Coleus (Plectranthus scutellarioides) plants were subjected to four common abiotic stress conditions individually: high soil salinity, droug

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Romanova, T. S., T. N. Myasnikova, and T. V. Latysheva. "Features of in vivo diagnostics of delayed drug hypersensitivity to beta-lactams." Russian Journal of Allergy 15, no. 4 (2018): 30–42. http://dx.doi.org/10.36691/rja134.

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Background. Beta-lactams are the most widely used group of antibacterial agents. They are used for treating of infectious complications of varying severity, including urgent situations. The exclusion of the entire beta-lactam group not only leads to a significant increase in the cost of treatment, length of hospitalization and the formation of resistance of the flora to alternative antibiotics, but also may be life threatening in some cases. Therefore, correct diagnosis and establishement of the offending medication can prevent the development of allergic reactions and to avoid unreasonable li

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Romanus, E., M. Hückel, C. Groß, et al. "Magnetic nanoparticle relaxation measurement as a novel tool for in vivo diagnostics." Journal of Magnetism and Magnetic Materials 252 (November 2002): 387–89. http://dx.doi.org/10.1016/s0304-8853(02)00645-5.

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Jütte, Lennart, and Bernhard Roth. "Mueller Matrix Microscopy for In Vivo Scar Tissue Diagnostics and Treatment Evaluation." Sensors 22, no. 23 (2022): 9349. http://dx.doi.org/10.3390/s22239349.

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Scars usually do not show strong contrast under standard skin examination relying on dermoscopes. They usually develop after skin injury when the body repairs the damaged tissue. In general, scars cause multiple types of distress such as movement restrictions, pain, itchiness and the psychological impact of the associated cosmetic disfigurement with no universally successful treatment option available at the moment. Scar treatment has significant economic impact as well. Mueller matrix polarimetry with integrated autofocus and automatic data registration can potentially improve scar assessment

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