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Dissertations / Theses on the topic 'In vivo tracking'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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1

Graves, S., C. Lewis, H. Valdovinos, et al. "In vivo cell tracking with 52Mn PET: Targetry, Separation, and Applications." Helmholtz-Zentrum Dresden - Rossendorf, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-166432.

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Introduction 52Mn (t½ =5.59 d, β+ = 29.6%, Eβmax = 0.58 MeV) has great potential as a long lived PET isotope for use in cell tracking studies, observation of immunologic response to disease states, or as an alternative to manganese-based MRI contrast agents. Its favorable max positron energy leads to superb imaging resolution, comparable to that of 18F.[1] Manganese is naturally taken up by cells via a multitude of pathways including the divalent metal transporter (DMT1), ZIP8, transferrin receptors (TfR), store-operated Ca2+ channels (SOC-Ca2+), and ionotropic glutamate receptor Ca2+ channel

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2

van, Gemeren Lindsey. "Imaging agents for mutlimodal in vivo immune cell tracking." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6585/.

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The aim of this work was to develop tri-modal cell labels for tracking immune cells in vivo, particularly for longitudinal studies of immune cell therapies. Localisation and quantification of the cells is invaluable in determining the effectiveness of these treatments, so imaging agents for fluorescence, \(^1\)H MRI and \(^19\)F MRI were combined. Four combinations of agents in a robust scaffold were investigated: luminescent dyes and a \(^1\)H MRI contrast agent were trapped electrostatically in a silica matrix; luminescent dyes and proton MRI agents were bound to silica and gold nanoparticle

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3

Lindström, John. "Method for tracking orthogonal ribosomes in vivo using MS2coat protein." Thesis, Uppsala universitet, Molekylärbiologi, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-388369.

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Ribosomes are large macromolecules responsible for protein synthesisand they consist of both RNA and proteins. Each ribosome is made of one large and one small subunit. Even though the ribosome is one of the most studied machineries in the cell there is a gap in our understanding of how this macromolecule functions in vivo. In this project we aimed to develop a method for tracking a specific subset of ribosomes using super-resolution fluorescence microscopy. This was achieved by using the MS2 coat protein (MS2CP) fused to a fluorescent marker and by modifying ribosomes to have the RNA loop to

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4

Błażków-Schmalzbauer, Katarzyna [Verfasser], and Riccardo [Akademischer Betreuer] Giunta. "In vivo Tracking von Mikrofetttransplantaten / Katarzyna Błażków-Schmalzbauer ; Betreuer: Riccardo Giunta." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2017. http://d-nb.info/1148276165/34.

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5

Broström, Oscar. "Development of a single-molecule tracking assay for the lac repressor in Escherichia coli." Thesis, Uppsala universitet, Institutionen för cell- och molekylärbiologi, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-388075.

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Gene regulation by transcription factors are one of the key processes that are important to sustain all kinds of life. In the prokaryote Escherichia coli this has shown to especially crucial. The operator sequence to which these transcription factors bind to are very small in comparison to the whole genome of E. coli, thus the question becomes how these proteins can find these sequences quickly. One particularly well-studied transcription factor in this regard is the lac repressor. It has been shown that this transcription factors finds its operators faster than the limit of three dimensional

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6

Delestro, Felipe. "A multiple cell tracking method dedicated to the analysis of memory formation in vivo." Thesis, Paris Sciences et Lettres (ComUE), 2018. http://www.theses.fr/2018PSLEE038/document.

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La formation et la consolidation de souvenirs est l’une des caractéristiques fondamentales du cerveau, responsable de l’apprentissage et de comportements cognitifs élevés. Malgré son importance, ce processus n’est pas entièrement compris à ce jour et fait l’objet de nombreux travaux de de recherche, allant de l’analyse de l’activité des synapses individuelles à la reconstruction de cartes de connectivité du cerveau. Dans ce travail, nous proposons une approche intégrée pour mesurer in vivo l’activité de chaque neurone du corps pédonculé (Mushroom body, MB) de la Drosophila melanogaster dans un

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Sweeney, Sean Kenneth. "Non-invasive stem cell tracking using novel nanomaterials : in vitro and ex vivo studies." Thesis, University of Iowa, 2012. https://ir.uiowa.edu/etd/2282.

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As research and clinical use of stem cell therapies progresses, it is becoming more evident that being able to visualize the stem cell transplant in vivo is of great benefit to the researcher or clinician. As a result, researchers are working to address this need. Our lab is collaborating to develop novel, multimodal nanomaterials, one with a core of mesoporous silica, and the other with a core of gadolinium oxide. Varying modifications have been made as needs arose. Human mesenchymal stem cells (MSCs) were isolated from bone marrow aspirates and confirmed to be positive for STRO-1, a common M

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8

Monem, Ramey G. "ATTENTIONAL BIAS TO ALCOHOL IN AN IN VIVO SETTING." UKnowledge, 2018. https://uknowledge.uky.edu/psychology_etds/146.

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The phenomenon of attentional bias to alcohol, where drinkers demonstrate a preference in allocating visual attention towards alcohol-related stimuli rather than neutral stimuli, is well-established. Studies detecting this phenomenon typically utilize computer-administered stimulus presentation tasks such as the visual dot probe task. Despite their frequency of use, these tasks do not represent the ways in which individuals typically encounter alcohol outside of the laboratory. Typical environments where alcohol is present allow individuals to move about freely and encounter alcohol while also

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Robson, Alex J. "Single particle tracking as a tool to investigate the dynamics of integrated membrane complexes in vivo." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:7769f80c-a56d-4513-9123-1d65ef8c9911.

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The last decade has seen substantial advances in single-molecule tracking methods with nano-metre level precision. A powerful tool in single-molecule tracking is fluorescence imaging. One particular application, total internal reflection microscopy, can capture biological processes at high contrast video rate imaging at the single-particle level. This thesis presents methodologically novel methods in analysing single particle tracking data. Presented here is an application of a Bayesian statistical approach that can discriminate between the different diffusive modes that appear with the presen

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Bouccara, Sophie. "Time-gated detection of near-infrared emitting quantum dots for in vivo cell tracking in small animals." Paris 7, 2014. https://pastel.archives-ouvertes.fr/tel-01083824.

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Le suivi de cellules in vivo est essentiel afin de déterminer par exemple les voies de migration de cellules tumorales circulantes ou encore pour suivre l'activité de cellules immunitaires. La microscopie de fluorescence assure une bonne résolution ainsi qu'une grande sensibilité et semble adaptée à la détection de cellules uniques in vivo dans un modèle de souris. Néanmoins, sa sensibilité est limitée par deux principaux facteurs: le signal d'autofluorescence des tissus d'une part, et l'absorption et la diffusion de la lumière visible dans les tissus d'autre part. Nous présentons la synthèse

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11

Potratz, Madlin [Verfasser], Stefan [Gutachter] Finke, and Martin [Gutachter] Schwemmle. "Pathogenitätsdeterminanten in Feld Rabies Virus Infektion und In Vivo Tracking / Madlin Potratz ; Gutachter: Stefan Finke, Martin Schwemmle." Greifswald : Universität Greifswald, 2021. http://d-nb.info/1240401132/34.

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12

Ordidge, K. L. "In vivo assessment of a novel dual cell cancer therapy using conventional and novel cell tracking methods." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1449824/.

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Adoptive immunotherapy for cancer is a rapidly expanding field. Along with new techniques and technologies for cell engineering comes a pressing clinical need to discover the location of these cells after injection and to quantify the number of cells in a particular location. The use of agents to enhance tissue contrast is crucial to improve the ability of imaging techniques to distinguish cells from background signal, in order to track cells in vivo. Human donor T cells were transduced to express a tumour antigen specific T cell receptor. Transduced T cells were labeled with novel and convent

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13

Burand, Jr Anthony John. "Consequences of in vitro and in vivo environmental cues on localized delivery of MSCs." Diss., University of Iowa, 2019. https://ir.uiowa.edu/etd/6919.

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Mesenchymal stromal cells (MSCs) are being explored for treatment of inflammatory, ischemic, autoimmune, and degenerative diseases. More and more of these diseases require MSCs to be delivered locally to the diseased site rather than systemically injected into patients. However, little is understood about whether cell cryopreservation or prelicensing will affect the efficacy of the locally injected product or how the local injection environment affects MSC expression of trophic factors and interactions with patient immune cells. Several groups have disagreed on whether cryopreservation hinders

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Correa, John Bernard. "An Experimental Evaluation of the Relationship Between In-Vivo Stimuli and Attentional Bias to Smoking and Food Cues Among Female Smokers." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5670.

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Background: Cross-sectional and experimental research has shown that female smokers more frequently report using cigarettes to control negative affect, manage dietary restraint, and suppress body image dissatisfaction. However, there has been little research to identify cognitive mechanisms that may underlie these effects. Cross-stimulus attentional bias is one such mechanism. Aims and Hypotheses: We hypothesized that, when compared to neutral stimuli, in-vivo appetitive stimuli would enhance motivation to obtain a particular substance. More specifically, in-vivo smoking stimuli would increase

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15

MacLeod, Megan Kathryn Louise. "Tracking memory CD4 T cells in vivo : requirements for the generation, survival and re-activation of memory cells." Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/12522.

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How memory cells form and how they survive are pertinent, unanswered questions in the field of immunology. T cell memory develops following an adaptive immune response, which is initiated in secondary lymphoid organs. This response involves T cell proliferation, effector cell differentiation and the generation of memory cells. It has proved difficult to study CD4 T cell responses due to the problems of tracking the small number of antigen specific T cells. MHC class II tetramers, which bind to the T cell receptor of responding T cells, enable the identification of antigen specific CD4 T cells

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16

Hävermark, Tora. "Single-particle tracking for direct measurements of Trigger Factor ribosome binding in live cells." Thesis, Uppsala universitet, Molekylärbiologi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-445886.

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Trigger Factor (TF) is a prokaryotic chaperone protein that exerts its major chaperone activity while associated with translating ribosomes, assisting de novo folding of the emerging nascent chain. Although much is known about the kinetics behind TF-ribosome binding, most results are based on in vitro experiments which fail to mimic the cellular environment. Single-particle approaches have gained increasing power for studying binding kinetics of biomolecules in living cells. One such method is single-particle tracking by super-resolution fluorescence microscopy, where the position of a fluores

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Alrashidi, Mohammad. "In vivo mechanical assessment of human elbow kinematics using a six axis parallel mechanism developed in house." Thesis, Brunel University, 2011. http://bura.brunel.ac.uk/handle/2438/9175.

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Elbow joint laxity is a problem that normally comes with age; it increases up to critical levels due to rupture or damage to the ligaments of the elbow and affects the stability and capacities of the joint, interfering even with daily activities. This work investigates the kinematics of the elbow through in-vivo experimental measurement. To this end, a platform based on Stewart Platform mechanism was built and used at the bioengineering labs of Brunel University in West London, the UK, to measure the six degrees of freedom of the joint. This thesis aims to develop a method to simulate such mot

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Almutairi, Haifa Matar H. "Application of global and regional myocardial deformation using cardiovascular magnetic resonance : an assessment of feature tracking in vivo and using numerical simulation." Thesis, Queen Mary, University of London, 2018. http://qmro.qmul.ac.uk/xmlui/handle/123456789/46025.

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Cardiovascular diseases are responsible for approximately a third of all death worldwide, with hypertension being a major risk factor for many of those. Hypertension can lead to left ventricle hypertrophy and diastolic and systolic dysfunction. Myocardial deformation parameters have been shown to have high sensitivity at the early stage of contractile dysfunction. They can be derived from myocardial tagging, considered to be the goldstandard method, or from routinely acquired cine images using feature tracking (FT) techniques. This work aimed to validate FT as a post processing technique. Thre

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19

Van, Vollenstee Fiona A. "Isolation and characterization of human adipose derived mesenchymal stem cells and production of GFP-labeled primary cells for in vivo tracking following transplantation." Diss., University of Pretoria, 2015. http://hdl.handle.net/2263/45939.

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Introduction It is well known that resident adipose stem/stromal cells (ASCs) are a heterogeneous population of multipotent cells characterized by (a) their ability to adhere to plastic; (b) immunophenotypic expression of certain cell surface markers, while lacking others; and (c) the capacity to differentiate into cells of mesodermal origin including osteocytes, chondrocytes and adipocytes. Adipose derived stromal cells offer great therapeutic potential in multiple medical fields, including, orthopedics, cardiology, oncology and degenerative diseases, to name a few. Combining different

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20

Widman, Erik. "Ultrasonic Methods for Quantitative Carotid Plaque Characterization." Doctoral thesis, KTH, Medicinsk bildteknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-192339.

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Cardiovascular diseases are the leading causes of death worldwide and improved diagnostic methods are needed for early intervention and to select the most suitable treatment for patients. Currently, carotid artery plaque vulnerability is typically determined by visually assessing ultrasound B-mode images, which is influenced by user-subjectivity. Since plaque vulnerability is correlated to the mechanical properties of the plaque, quantitative techniques are needed to estimate plaque stiffness as a surrogate for plaque vulnerability, which would reduce subjectivity during plaque assessment. The

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Ravarani, Lisa [Verfasser], Ernst J. [Akademischer Betreuer] Rummeny, and Reinhard [Akademischer Betreuer] Meier. "Optical Imaging allows in vivo tracking of theranostic liposomes to ovarian cancers / Lisa Ravarani. Gutachter: Reinhard Meier ; Ernst J. Rummeny. Betreuer: Ernst J. Rummeny." München : Universitätsbibliothek der TU München, 2013. http://d-nb.info/1051078261/34.

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22

Yusufi, Nahid [Verfasser], Markus [Akademischer Betreuer] Schwaiger, Markus [Gutachter] Schwaiger, Gabriele [Gutachter] Multhoff, and Peter [Gutachter] Bartenstein. "Establishment of in vivo imaging strategies for tracking of TCR-transgenic T cells / Nahid Yusufi ; Gutachter: Markus Schwaiger, Gabriele Multhoff, Peter Bartenstein ; Betreuer: Markus Schwaiger." München : Universitätsbibliothek der TU München, 2019. http://d-nb.info/1190818671/34.

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23

Rajaraman, Swaminathan. "Micromachined three-dimensional electrode arrays for in-vitro and in-vivo electrogenic cellular networks." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/28129.

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Thesis (M. S.)--Electrical and Computer Engineering, Georgia Institute of Technology, 2009.<br>Committee Chair: Mark G. Allen; Committee Member: Elliot L. Chaikof; Committee Member: Ionnis (John) Papapolymerou; Committee Member: Maysam Ghovanloo; Committee Member: Oliver Brand.

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Dupont, Damien. "Cartographie in vivo des remaniements anatomo-fonctionnels de l’architecture des réseaux neuronaux dans le système nerveux central au cours du développement par Imagerie du Tenseur de Diffusion et Imagerie renforcée par le manganèse." Thesis, Paris 11, 2013. http://www.theses.fr/2013PA112021/document.

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L’objectif de cette thèse est de développer des méthodes IRM permettant d’étudier l’impact d’une ischémie focale transitoire sur le cerveau de rat nouveau-né. Les techniques utilisées sont l’imagerie à contraste renforcé par le manganèse (MEMRI), l’imagerie du tenseur de diffusion (DTI) ainsi que de façon préliminaire l’imagerie Q-ball (QBI). Le MEMRI après injection intra cérébrale a été utilisé afin d’étudier de manière dynamique le tractus cortico-thalamique, en parallèle le DTI a servi de marqueur de la structuration cérébrale. Les résultats ont montré une atteinte du tractus cortico-thala

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Teston, Eliott. "Nanohybrides superparamagnétiques à luminescence persistante : conception et application au marquage cellulaire pour la vectorisation magnétique in vivo." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCB025/document.

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La thérapie cellulaire consiste à utiliser des cellules comme médicament injectable dans le but de favoriser la réparation d'un tissu ou d'un organe. Certaines cellules possèdent la propriété de stimuler la formation de nouveaux vaisseaux sanguins. Elles présentent un intérêt pour le développement d'un traitement des ischémies des membres inférieurs ou du myocarde. Déterminer le devenir de ces cellules après injection in vivo est important pour comprendre les mécanismes responsables de l'efficacité d'un tel traitement. Cependant, il est difficile à observer et très peu décrit dans la littératu

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Rane, Swati. "Diffusion tensor imaging at long diffusion time." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/29708.

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Thesis (Ph.D)--Biomedical Engineering, Georgia Institute of Technology, 2009.<br>Committee Chair: Hu, Xiaoping; Committee Member: Brummer, Marijn; Committee Member: Duong, Tim; Committee Member: Keilholz, Shella; Committee Member: Schumacher, Eric. Part of the SMARTech Electronic Thesis and Dissertation Collection.

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Hemmer, Caroline. "Développement et utilisation de nanobodies dirigés contre le Grapevine fanleaf virus (GFLV) en lutte antivirale et comme biocapteur in planta." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAJ085/document.

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Par leur stabilité, leur petite taille et leur nature monomérique, les domaines variables des immunoglobulines à chaînes lourdes, ou Nanobodies (Nb), sont incontournables en diagnostic et recherche médicale. Pourtant, leur utilisation en agro-biotechnologies demeure confidentielle.Dans l'idée de les utiliser pour étudier et combattre le Grapevine fanleaf virus (GFLV), responsable de la maladie du court-noué très préjudiciable à l'économie viticole mondiale, j'ai produit une collection de Nb spécifiques du GFLV.Fusionné à une protéine fluorescente et exprimé en plante de façon stable, un de ces

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Lam, Benny, and Jakob Nilsson. "Creating Good User Experience in a Hand-Gesture-Based Augmented Reality Game." Thesis, Linköpings universitet, Institutionen för datavetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-156878.

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The dissemination of new innovative technology requires feasibility and simplicity. The problem with marker-based augmented reality is similar to glove-based hand gesture recognition: they both require an additional component to function. This thesis investigates the possibility of combining markerless augmented reality together with appearance-based hand gesture recognition by implementing a game with good user experience. The methods employed in this research consist of a game implementation and a pre-study meant for measuring interactive accuracy and precision, and for deciding upon which g

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Cui, Jing. "In vivo multi-leukocyte tracking by enhanced particle filter /." 2006. http://wwwlib.umi.com/dissertations/fullcit/3225920.

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Chen, Shih-Hsien, та 陳世賢. "MR imaging with βG activity for tumor detecting and tracking in vivo". Thesis, 2012. http://ndltd.ncl.edu.tw/handle/69199701295379627450.

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博士<br>高雄醫學大學<br>醫學研究所<br>100<br>Cancer is still one of the leading causes of human death in recent years despite scientists around the world have put a lot of effort to develop better therapies. Gene therapy is one of the target therapies under intense development. Therefore, a new imaging technique is tried to develop through magnetic resonance imaging (MRI) contrast agents, which is able to reflect special biological activity in vivo. The special agents may be able to detect tumor location, to determine its size and to reflect certain molecular process on MRI. If it works properly, clinician

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Ray, Nilanjan. "Tracking rolling leukocytes in vivo using active contours with motion gradient vector flow /." 2003. http://wwwlib.umi.com/dissertations/fullcit/3083130.

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Joshi, Pratixa Paritosh. "Near-IR plasmonic contrast agents for molecular imaging, cell tracking and clinical translation." Thesis, 2014. http://hdl.handle.net/2152/30333.

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Gold nanoparticles attain an intense focus in biomedical imaging applications due to their unique optical properties, facile conjugation with biomolecules, and biocompatibility. Although a considerable amount of work towards the development of gold nanoparticles has been completed, these promising contrast agents have not yet reached the clinic due to several challenges including efficient accumulation at the diseased site, sensitivity of detection in vivo, potential adverse effects, and clearance from the body. High signal-to-background ratio is required to enhance sensitivity of detection. B

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Levitz, Andrew R. "Synthesis of Various Classes of Cyanine Fluorophores and Their Application In In Vivo Tissue Imaging." 2017. http://scholarworks.gsu.edu/chemistry_diss/130.

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A novel series of near-infrared fluorescent contrast agents was developed and characterized. Their physicochemical and optical properties were measured. By altering functional groups of cyanine fluorophores, the selective targeting of endocrine glands, exocrine glands, cartilage and bone using NIR fluorescence to visualize the targeted tissue has been reported. These agents have high specificity for tissue targeting inherent to the chemical structure of the fluorophore. After a single low-dose intravenous injection these agents have high specificity for tissue targeting inherent to the chemica

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Chan, Ming-Hsien, and 詹明賢. "The Preparation and Identification of Multifunctional Mesoporous Silica Nanoparticles for Dual-Mode Imaging, Theranostics, and Targeted Tracking in vivo." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/tb6359.

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碩士<br>國立臺灣海洋大學<br>生物科技研究所<br>102<br>The use of nanoparticles imaging agents in diagnosis and therapy is receiving considerable attention in recent years, the research teams involving physicists and material chemists are interest in the multifunctional mesoporous silica nanoparticles (MSNs) because of the dual-model for imaging and therapy. This field is expanding rapidly, bringing a new term: theranostic, which means a combination of therapeutics and diagnostics. Comparing with the traditional imaging agent, MSNs have many advanced features to develop into a multifunctional platform by elabora

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Barbi, Martina. "Location and Tracking for Ultra-WideBand In-Body Communications in Medical Applications." Doctoral thesis, 2019. http://hdl.handle.net/10251/132874.

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[ES] La cápsula inalámbrica de endoscopia (WCE) es una tecnología notable y atractiva adoptada en el sector biomédico hace varios años. WCE proporciona una tecnología de imagen inalámbrica no invasiva que permite a los especialistas reconocer y diagnosticar enfermedades que afectan todo el tracto gastrointestinal. Aunque los médicos pueden recibir imágenes claras de anomalías en el tracto gastrointestinal, no tienen información sobre sus exacta ubicación. La localización precisa de los trastornos detectados es crucial para el posterior procedimiento de extracción mediante cirugía. Actualmente,

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Lai, Pei-Yu, and 賴沛妤. "Multi-functional optical coherence tomography for the in vivo longitudinal tracking of lymphangiography and angiography in a cutaneous melanoma mouse model." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/hy7df7.

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Kwek, Kian-Keat, and 郭晉傑. "Preparation of a dual-target tracking, dual-mode imaging multifunctional mesoporous silica nanoparticles for the treatment and diagnosis of tumors in vivo." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/34571935099693409687.

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碩士<br>國立臺灣海洋大學<br>生命科學暨生物科技學系<br>104<br>Multifunctional mesoporous silica nanoparticles (MSN) in the biomedical field has been outstanding intelligent drug carrier, which features high specific surface area, high biocompatibility and ease of modification of surface in the past decade it has been great concern. On MSN surface modified folic acid (FA) and glucose (Glu) as a targeting molecule, as has excess folic acid receptor and Glucose transporter (GLUT) on cancer cells, makes MSN (MSN-EuGd-FA-Glu) more able to bind to specific cancer cells, thus enhancing drug delivery efficiency, Drug relea

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Cheng, Chi-An, and 程吉安. "Fluorescent Nanodiamond as a Biocompatible Nanoparticle Platform and its Application for Long-Term Stem Cell Tracking and In Vivo Lung Stem Cell Sorting." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/04327715915749010432.

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碩士<br>國立臺灣大學<br>化學研究所<br>99<br>Fluorescent nanodiamond (FND) is a sp3-carbon-based nanomaterial produced by radiation-damage followed by annealing. FND possess several unique properties such as excellent biocompatibility, facile surface modification, high tissue-penetrable red fluorescence and outstanding photostability, making it well suited for long-term labeling and tracking of cells. In this study, we use surface-oxidized FND particles (size~100nm) as the cell tracker. We introduce FNDs into cells by endocytosis through incubation, and do flow cytometric analysis. Based on different cell t

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Aziz, Azaam. "Medical Imaging of Magnetic Micromotors Through Scattering Tissues." 2020. https://monarch.qucosa.de/id/qucosa%3A73896.

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Micro- and nanorobots (MNRs) are small autonomous devices capable of performing complex tasks and have been demonstrated for a variety of non-invasive biomedical applications, such as tissue engineering, drug delivery or assisted fertilization. However, translating such approaches to an in vivo environment is critical. Current imaging techniques do not allow localization and tracking of single or few micromotors at high spatiotemporal resolution in deep tissue. This thesis addresses some of these limitations, by exploring the use of two optical-based techniques (IR and photoacoustic imaging (P

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