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Journal articles on the topic 'Inactivation of B'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Dong, Yi-Hu, Andi R. Gusti, Qiong Zhang, Jin-Ling Xu, and Lian-Hui Zhang. "Identification of Quorum-Quenching N-Acyl Homoserine Lactonases from Bacillus Species." Applied and Environmental Microbiology 68, no. 4 (2002): 1754–59. http://dx.doi.org/10.1128/aem.68.4.1754-1759.2002.

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ABSTRACT A range of gram-negative bacterial species use N-acyl homoserine lactone (AHL) molecules as quorum-sensing signals to regulate different biological functions, including production of virulence factors. AHL is also known as an autoinducer. An autoinducer inactivation gene, aiiA, coding for an AHL lactonase, was cloned from a bacterial isolate, Bacillus sp. strain 240B1. Here we report identification of more than 20 bacterial isolates capable of enzymatic inactivation of AHLs from different sources. Eight isolates showing strong AHL-inactivating enzyme activity were selected for a preli

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2

Docquier, Jean-Denis, Teresa Lopizzo, Sabrina Liberatori та ін. "Biochemical Characterization of the THIN-B Metallo-β-Lactamase of Janthinobacterium lividum". Antimicrobial Agents and Chemotherapy 48, № 12 (2004): 4778–83. http://dx.doi.org/10.1128/aac.48.12.4778-4783.2004.

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ABSTRACT The THIN-B metallo-β-lactamase, a subclass B3 enzyme produced by the environmental species Janthinobacterium lividum, was overproduced in Escherichia coli by means of a T7-based expression system. The enzyme was purified (>95%) by two ion-exchange chromatography steps and subjected to biochemical analysis. The native THIN-B enzyme is a monomeric protein of 31 kDa. It exhibits the highest catalytic efficiencies with carbapenem substrates and cephalosporins, except for cephaloridine, which acts as a poor inactivator. Individual rate constants for inactivation by chelators were measur

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ANDO, YUKIO, and MASAYASU INOUE. "PHOTOOXIDATIVE INACTIVATION OF ECTOENZYMES ON EPITHELIAL CELL MEMBRANES ." Biomedical Research 13, no. 5 (1992): 365–69. http://dx.doi.org/10.2220/biomedres.13.365.

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4

Fineberg, Jeffrey D., David M. Ritter, and Manuel Covarrubias. "Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels." Journal of General Physiology 140, no. 5 (2012): 513–27. http://dx.doi.org/10.1085/jgp.201210869.

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A-type voltage-gated K+ (Kv) channels self-regulate their activity by inactivating directly from the open state (open-state inactivation [OSI]) or by inactivating before they open (closed-state inactivation [CSI]). To determine the inactivation pathways, it is often necessary to apply several pulse protocols, pore blockers, single-channel recording, and kinetic modeling. However, intrinsic hurdles may preclude the standardized application of these methods. Here, we implemented a simple method inspired by earlier studies of Na+ channels to analyze macroscopic inactivation and conclusively deduc

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5

Torkkeli, Päivi H., Shin-Ichi Sekizawa, and Andrew S. French. "Inactivation of Voltage-Activated Na+ Currents Contributes to Different Adaptation Properties of Paired Mechanosensory Neurons." Journal of Neurophysiology 85, no. 4 (2001): 1595–602. http://dx.doi.org/10.1152/jn.2001.85.4.1595.

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Voltage-activated sodium current ( I Na) is primarily responsible for the leading edge of the action potential in many neurons. While I Na generally activates rapidly when a neuron is depolarized, its inactivation properties differ significantly between different neurons and even within one neuron, where I Na often has slowly and rapidly inactivating components. I Nainactivation has been suggested to regulate action potential firing frequency in some cells, but no clear picture of this relationship has emerged. We studied I Na in both members of the paired mechanosensory neurons of a spider sl

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6

Meyer, Hemmo, Alicja Drozdowska, and Grzegorz Dobrynin. "A role for Cdc48/p97 and Aurora B in controlling chromatin condensation during exit from mitosisThis paper is one of a selection of papers published in this special issue entitled 8th International Conference on AAA Proteins and has undergone the Journal's usual peer review process." Biochemistry and Cell Biology 88, no. 1 (2010): 23–28. http://dx.doi.org/10.1139/o09-119.

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During cell division, chromosomes condense so that the replicated chromatids can be segregated by the mitotic spindle. While condensation is governed by cyclin-dependent kinase 1 (Cdk1) during mitotic entry and early mitosis, it is still poorly understood how condensation is maintained during anaphase after Cdk1 inactivation, and how decondensation is triggered in telophase. Here, we review recent reports that point to a novel role of Aurora B kinase in maintaining condensation and preventing premature nuclear envelope formation during exit from mitosis. Timely decondensation and nuclear envel

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7

Suprynowicz, F. A. "Inactivation of cdc2 kinase during mitosis requires regulated and constitutive proteins in a cell-free system." Journal of Cell Science 104, no. 3 (1993): 873–81. http://dx.doi.org/10.1242/jcs.104.3.873.

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Inactivation of the cyclin-p34cdc2 protein kinase complex is a major requirement for anaphase onset and exit from mitosis. To facilitate identification of specific molecules that regulate this event in mammalian cells, I have developed a cell-free assay in which cdc2 kinase associated with a chromosomal fraction from metaphase tissue culture cells is inactivated by a cell-cycle-regulated cytosolic system. In vitro kinase inactivation requires ATP, Mg2+ and the dephosphorylation of one or more sites in the chromosomal fraction by protein phosphatase 1 and/or 2A. Cyclin B is destroyed during ina

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8

Liu, Feng, Zhong Lin Chen, and Sheng Chang. "Evaluation of Chlorine for Inactivation of Bioterrorism Agents in Drinking Water." Applied Mechanics and Materials 295-298 (February 2013): 599–603. http://dx.doi.org/10.4028/www.scientific.net/amm.295-298.599.

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The object of this paper is to measure the characteristics of the inactivation kinetics of B. subtilis spores-surrogates for B. anthracis spores following the treatment with free chlorine. The results indicated that the inactivation kinetics of B. subtilis spores with free chlorine was characterized by a lag phase followed by a pseudo-first-order rate of inactivation. The magnitude of the lag phase increased and the rate of subsequent inactivation decreased with the decreasing temperature, for the experimental temperature range of 1-30 °C. The same tendency of inactivation kinetics curves was

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9

Fung, Tsz Kan, Hoi Tang Ma, and Randy Y. C. Poon. "Specialized Roles of the Two Mitotic Cyclins in Somatic Cells: Cyclin A as an Activator of M Phase–promoting Factor." Molecular Biology of the Cell 18, no. 5 (2007): 1861–73. http://dx.doi.org/10.1091/mbc.e06-12-1092.

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The role of cyclin B-CDC2 as M phase-promoting factor (MPF) is well established, but the precise functions of cyclin A remain a crucial outstanding issue. Here we show that down-regulation of cyclin A induces a G2 phase arrest through a checkpoint-independent inactivation of cyclin B-CDC2 by inhibitory phosphorylation. The phenotype is rescued by expressing cyclin A resistant to the RNA interference. In contrast, down-regulation of cyclin B disrupts mitosis without inactivating cyclin A-CDK, indicating that cyclin A-CDK acts upstream of cyclin B-CDC2. Even when ectopically expressed, cyclin A

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10

Mbonimpa, E. G., E. R. Blatchley, B. Applegate, and W. F. Harper. "Ultraviolet A and B wavelength-dependent inactivation of viruses and bacteria in the water." Journal of Water and Health 16, no. 5 (2018): 796–806. http://dx.doi.org/10.2166/wh.2018.071.

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AbstractUVA and UVB can be applied to solar disinfection of water. In this study, the inactivation and photoreactivation of viruses and bacteria in the UVA-B range were analyzed. MS2 and T4 bacteriophages, and Escherichia coli were used as surrogates to quantify dose-response behaviors. Inactivation in UVC was used to validate the methodology and to expand the inactivation action spectra. The results showed log-linear inactivation for MS2 and T4 in the 254–320 nm wavelength range. T4 inactivation was consistently faster than MS2 (except at 320 nm), and for both phages, inactivation decreased w

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11

Hansen, P. J. "Chemical inactivation of HIV on surfaces." British Medical Journal 299, no. 6693 (1989): 260.2–260. http://dx.doi.org/10.1136/bmj.299.6693.260-b.

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12

Oktavia, Listiana, Irma Mulyani, and Veinardi Suendo. "Investigation of Chlorophyl-a Derived Compounds as Photosensitizer for Photodynamic Inactivation." Bulletin of Chemical Reaction Engineering & Catalysis 16, no. 1 (2021): 161–69. http://dx.doi.org/10.9767/bcrec.16.1.10314.161-169.

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Chlorophyll has unique physicochemical properties which makes them good as photosensitizer of Photodynamic Inactivation (PDI). The physicochemical properties of chlorophyll as photosensitizer can be optimized through several routes. One of the possible route is by replacing the metal ion center of chlorophyll with other ions. In this research, the effect of coordinated metal ion in the natural chlorophyll-a was studied for bacterial growth (S. aureus) inhibition. The replacement of metal in the center of chlorophyll hopefully can improve the intensity of Intersystem Crossing Mechanism (ISC) le

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13

Houška, M., K. Kýhos, A. Landfeld, et al. "Dry heat inactivation of Bacillus cereus in rice." Czech Journal of Food Sciences 25, No. 4 (2008): 208–13. http://dx.doi.org/10.17221/692-cjfs.

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The aim of this work was to validate the method of decontamination of rice at the temperature of 120°C (determined as optimal in previous experiments). <i>Bacillus cereus</i> was selected as the marker micro-organism for the monitoring of decontamination. The spores of <i>Bacillus cereus</i> are moderately heat resistant. In order to show the efficacy of our decontamination process, we artificially contaminated the rice under study with <i>B. cereus</i>. Decontamination was carried out in a homogenising steriliser about 20 h after contamination. The sample w

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14

Bean, Christine, Jacqueline Hansen, Aaron Margolin, Helene Balkin, Glenda Batzer, and Giovanni Widmer. "Class B Alkaline Stabilization to Achieve Pathogen Inactivation." International Journal of Environmental Research and Public Health 4, no. 1 (2007): 53–60. http://dx.doi.org/10.3390/ijerph2007010009.

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15

Mitchell, Deanna J., Dejan Nikolic, Richard B. van Breemen, and Richard B. Silverman. "Inactivation of monoamine oxidase B by 1-phenylcyclopropylamine." Bioorganic & Medicinal Chemistry Letters 11, no. 13 (2001): 1757–60. http://dx.doi.org/10.1016/s0960-894x(01)00302-x.

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16

Kato, Motohiro, Masashi Sanada, Itaru Kato, et al. "Frequent inactivation of A20 in B-cell lymphomas." Nature 459, no. 7247 (2009): 712–16. http://dx.doi.org/10.1038/nature07969.

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17

Monfort, Asun, and Anton Wutz. "The B-side of Xist." F1000Research 9 (January 28, 2020): 55. http://dx.doi.org/10.12688/f1000research.21362.1.

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Female mammals express the long noncoding X inactivation-specific transcript (Xist) RNA to initiate X chromosome inactivation (XCI) that eventually results in the formation of the Barr body. Xist encompasses half a dozen repeated sequence stretches containing motifs for RNA-binding proteins that recruit effector complexes with functions for silencing genes and establishing a repressive chromatin configuration. Functional characterization of these effector proteins unveils the cooperation of a number of pathways to repress genes on the inactive X chromosome. Mechanistic insights can be extended

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18

Duizer, Erwin, Paul Bijkerk, Barry Rockx, Astrid de Groot, Fleur Twisk, and Marion Koopmans. "Inactivation of Caliciviruses." Applied and Environmental Microbiology 70, no. 8 (2004): 4538–43. http://dx.doi.org/10.1128/aem.70.8.4538-4543.2004.

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ABSTRACT The viruses most commonly associated with food- and waterborne outbreaks of gastroenteritis are the noroviruses. The lack of a culture method for noroviruses warrants the use of cultivable model viruses to gain more insight on their transmission routes and inactivation methods. We studied the inactivation of the reported enteric canine calicivirus no. 48 (CaCV) and the respiratory feline calicivirus F9 (FeCV) and correlated inactivation to reduction in PCR units of FeCV, CaCV, and a norovirus. Inactivation of suspended viruses was temperature and time dependent in the range from 0 to

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19

DeCoursey, T. E. "State-dependent inactivation of K+ currents in rat type II alveolar epithelial cells." Journal of General Physiology 95, no. 4 (1990): 617–46. http://dx.doi.org/10.1085/jgp.95.4.617.

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Inactivation of K+ channels responsible for delayed rectification in rat type II alveolar epithelial cells was studied in Ringer, 160 mM K-Ringer, and 20 mM Ca-Ringer. Inactivation is slower and less complete when the extracellular K+ concentration is increased from 4.5 to 160 mM. Inactivation is faster and more complete when the extracellular Ca2+ concentration is increased from 2 to 20 mM. Several observations suggest that inactivation is state-dependent. In each of these solutions depolarization to potentials near threshold results in slow and partial inactivation, whereas depolarization to

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20

Margosch, Dirk, Michael G. Gänzle, Matthias A. Ehrmann, and Rudi F. Vogel. "Pressure Inactivation of Bacillus Endospores." Applied and Environmental Microbiology 70, no. 12 (2004): 7321–28. http://dx.doi.org/10.1128/aem.70.12.7321-7328.2004.

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ABSTRACT The inactivation of bacterial endospores by hydrostatic pressure requires the combined application of heat and pressure. We have determined the resistance of spores of 14 food isolates and 5 laboratory strains of Bacillus subtilis, B. amyloliquefaciens, and B. licheniformis to treatments with pressure and temperature (200 to 800 MPa and 60 to 80°C) in mashed carrots. A large variation in the pressure resistance of spores was observed, and their reduction by treatments with 800 MPa and 70°C for 4 min ranged from more than 6 log units to no reduction. The sporulation conditions further

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21

Mottok, Anja, Christoph Renné, Marc Seifert, et al. "Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities." Blood 114, no. 20 (2009): 4503–6. http://dx.doi.org/10.1182/blood-2009-06-225839.

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Abstract STATs are constitutively activated in several malignancies. In primary mediastinal large B-cell lymphoma and Hodgkin lymphoma (HL), inactivating mutations in SOCS1, an inhibitor of JAK/STAT signaling, contribute to deregulated STAT activity. Based on indications that the SOCS1 mutations are caused by the B cell–specific somatic hypermutation (SHM) process, we analyzed B-cell non-HL and normal B cells for mutations in SOCS1. One-fourth of diffuse large B-cell lymphoma and follicular lymphomas carried SOCS1 mutations, which were preferentially targeted to SHM hotspot motifs and frequent

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22

OH, SANGSUK, and MYOUNG-JOO MOON. "Inactivation of Bacillus cereus Spores by High Hydrostatic Pressure at Different Temperatures." Journal of Food Protection 66, no. 4 (2003): 599–603. http://dx.doi.org/10.4315/0362-028x-66.4.599.

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The effect of pH on the initiation of germination and on the inactivation of Bacillus cereus (KCTC 1012) spores during high hydrostatic pressure processing (HPP) with pressures of 0.1 to 600 MPa at different temperatures was investigated. Two different high-pressure treatments were adopted to evaluate the effect of pH on the inactivation of B. cereus on sporulation medium and in suspension medium. Inactivation of B. cereus spores with HPP treatment was affected more by sporulation medium pH than by suspension medium pH. B. cereus spores obtained through sporulation at pH 6.0 showed more resist

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23

Grigoriev, N. G., J. D. Spafford, J. Przysiezniak, and A. N. Spencer. "A cardiac-like sodium current in motor neurons of a jellyfish." Journal of Neurophysiology 76, no. 4 (1996): 2240–49. http://dx.doi.org/10.1152/jn.1996.76.4.2240.

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1. Whole cell voltage-clamp recordings from isolated swimming motor neurons (SMNs) reveal a rapidly activating and inactivating sodium current. 2. Permeability ratios of PLi/PNa = 0.941 and P(guanidinium)/PNa = 0.124 were measured for the mediating channel, which was impermeable to rubidium. 3. The conductance/voltage and steady state inactivation curves are shifted in a depolarizing direction by approximately 45 mV relative to most neuronal sodium currents in higher animals. 4. Activation could be fitted with two exponents and maximal current peaked at 0.74 +/- 0.06 ms (mean +/- SD). 5. Inact

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Dündar, Gönül, Mika Teranishi, and Jun Hidema. "Autophagy-deficient Arabidopsis mutant atg5, which shows ultraviolet-B sensitivity, cannot remove ultraviolet-B-induced fragmented mitochondria." Photochemical & Photobiological Sciences 19, no. 12 (2020): 1717–29. http://dx.doi.org/10.1039/c9pp00479c.

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25

Yu, Bingfei, Yanyan Qi, Rui Li, Quanming Shi, Ansuman T. Satpathy, and Howard Y. Chang. "B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells." Cell 184, no. 7 (2021): 1790–803. http://dx.doi.org/10.1016/j.cell.2021.02.015.

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26

Diston, David, James E. Ebdon, and Huw D. Taylor. "Inactivation of Bacteriophage InfectingBacteroidesStrain GB124 Using UV-B Radiation." Photochemistry and Photobiology 90, no. 3 (2014): 622–27. http://dx.doi.org/10.1111/php.12223.

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27

Clarke, Joanna. "B cell X-chromosome inactivation is faulty in SLE." Nature Reviews Rheumatology 17, no. 8 (2021): 442. http://dx.doi.org/10.1038/s41584-021-00660-9.

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28

Scheibel, Elma, Jørgen Ingerslev, Marianne Schwartz, and Karen Ørstavik. "Absence of Correlation between X Chromosome Inactivation Pattern and Plasma Concentration of Factor VIII and Factor IX in Carriers of Haemophilia A and B." Thrombosis and Haemostasis 83, no. 03 (2000): 433–37. http://dx.doi.org/10.1055/s-0037-1613833.

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SummaryHaemophilia A and B are X-linked disorders which are due to a reduced activity of coagulation factor VIII or IX, respectively. Female carriers have a wide range of plasma concentration of factor VIII or factor IX, and may in rare cases have an affected phenotype. In order to investigate if this variation is related to X chromosome inactivation, we determined the X inactivation pattern in 31 haemophilia A and 15 haemophilia B carriers, using a PCR in the androgen receptor locus in blood DNA. Seven of the haemophilia A carriers and none of the haemophilia B carriers had a skewed pattern (

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29

Sambegoro, Poetro, Maya Fitriyanti, Bentang Arief Budiman, et al. "Bacterial Cell Inactivation Using a Single-Frequency Batch-Type Ultrasound Device." Indonesian Journal of Science and Technology 6, no. 1 (2021): 65–80. http://dx.doi.org/10.17509/ijost.v6i1.31516.

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Ultrasound technology employs cavitation to generate high-pressure soundwaves to disrupt bacterial cells. This study reveals the effectiveness of a single frequency ultrasound device for bacterial cell inactivation. A low-cost ultrasound device having a single frequency, i.e. 22 kHz for lab-scale application, was developed first, and the prototype was mechanically designed and analyzed using the finite-element method to assure the targeted natural frequency could be achieved. The prototype was then tested inactivating bacterial cells, Escherichia coli (E. coli) and Bacillus subtilis (B. subtil

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Edgerton-Morgan, Heather, та Berl R. Oakley. "γ-Tubulin plays a key role in inactivating APC/CCdh1 at the G1–S boundary". Journal of Cell Biology 198, № 5 (2012): 785–91. http://dx.doi.org/10.1083/jcb.201203115.

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A γ-tubulin mutation in Aspergillus nidulans, mipA-D159, causes failure of inactivation of the anaphase-promoting complex/cyclosome (APC/C) in interphase, resulting in failure of cyclin B (CB) accumulation and removal of nuclei from the cell cycle. We have investigated the role of CdhA, the A. nidulans homologue of the APC/C activator protein Cdh1, in γ-tubulin–dependent inactivation of the APC/C. CdhA was not essential, but it targeted CB for destruction in G1, and APC/CCdhA had to be inactivated for the G1–S transition. mipA-D159 altered the localization pattern of CdhA, and deletion of the

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Caspari, G. "Are inactivation procedures for blood products good or bad?" BMJ 325, no. 7372 (2002): 1116b—1116. http://dx.doi.org/10.1136/bmj.325.7372.1116/b.

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Periago, P. M., A. Fernández, J. Collado, and A. Martínez. "Note: Use of a Distribution of Frequencies Model to Interpret the Tailed Heat Inactivation Curves of Prions." Food Science and Technology International 9, no. 1 (2003): 29–32. http://dx.doi.org/10.1177/1082013203009001005.

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Inactivation of prions responsible of bovine spongiform encephalytis (BSE) by heat is a major concern for the canned food industry in Europe. Experimental data of heat inactivation of prions obtained from the scientific literature have been modelled. Two models were applied to analyse the inactivation curves, the Weibull distribution model and a two-parameter empirical model. Statistical analysis of available data indicated that the Weibull frequency distribution provided the best description of non-linear survival curves. The effect of the temperature on Weibull model parameters ( a and b) wa

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Nicholson, Wayne L., and Belinda Galeano. "UV Resistance of Bacillus anthracis Spores Revisited: Validation of Bacillus subtilis Spores as UV Surrogates for Spores of B. anthracis Sterne." Applied and Environmental Microbiology 69, no. 2 (2003): 1327–30. http://dx.doi.org/10.1128/aem.69.2.1327-1330.2003.

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ABSTRACT Recent bioterrorism concerns have prompted renewed efforts towards understanding the biology of bacterial spore resistance to radiation with a special emphasis on the spores of Bacillus anthracis. A review of the literature revealed that B. anthracis Sterne spores may be three to four times more resistant to 254-nm-wavelength UV than are spores of commonly used indicator strains of Bacillus subtilis. To test this notion, B. anthracis Sterne spores were purified and their UV inactivation kinetics were determined in parallel with those of the spores of two indicator strains of B. subtil

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Earl Patton, D., James W. West, William A. Catterall, and Alan L. Goldin. "A peptide segment critical for sodium channel inactivation functions as an inactivation gate in a potassium channel." Neuron 11, no. 5 (1993): 967–74. http://dx.doi.org/10.1016/0896-6273(93)90125-b.

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LYNCH, DONALD J., and NORMAN N. POTTER. "Effects of Organic Acids on Thermal Inactivation of Bacillus stearothermophilus and Bacillus coagulans Spores in Frankfurter Emulsion Slurry." Journal of Food Protection 51, no. 6 (1988): 475–80. http://dx.doi.org/10.4315/0362-028x-51.6.475.

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Malic, acetic, citric, lactic and hydrochloric acids were compared for their effects on thermal inactivation of Bacillus stearothermophilus and Bacillus coagulans spores in a frankfurter emulsion slurry adjusted to specific pH values. For B. stearothermophilus at 121°C and pH 5.2 no differences in thermal death rate constants attributable to the acids were noted, but at pH 4.6 a greater inactivation rate was obtained using lactic, citric or acetic acids than malic or hydrochloric acids. For B. coagulans at 110 or 105 °C and pH 4.5, there was no difference in spore inactivation noted between th

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Yan, Catherine T., Parames Muniandy, and Xiaoli Yang. "Conditional C-Myc Inactivation Impacts on Chromosomal Translocation Mechanisms and B Lymphomagenesis." Blood 118, no. 21 (2011): 5238. http://dx.doi.org/10.1182/blood.v118.21.5238.5238.

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Abstract Abstract 5238 The requirement for Myc oncogenes in cellular transformation and tumor progression in human cancers has been studied extensively. Others and we have shown that the spontaneous development and progression of B lymphomas involving translocations that activate c-Myc can be faithfully recapitulated in model systems. However, for other oncogenes that are the predominant translocation targets in hematopoietic malignancies in humans, such as Bcl6, animal models that spontaneously promote translocations involving them are still lacking. Importantly, the molecular basis for the r

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Torkkeli, Päivi H., and Andrew S. French. "Simulation of Different Firing Patterns in Paired Spider Mechanoreceptor Neurons: The Role of Na+ Channel Inactivation." Journal of Neurophysiology 87, no. 3 (2002): 1363–68. http://dx.doi.org/10.1152/jn.00440.2001.

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The spider VS-3 slit-sense organ contains two types of primary mechanoreceptor neurons that are morphologically similar but have different electrical behavior. Type A neurons fire only one or two action potentials in response to a mechanical or electrical step of any amplitude above the threshold, whereas type B neurons fire prolonged bursts of action potentials in response to similar stimuli. Voltage-clamp studies have shown that two voltage-activated ion currents, a noninactivating potassium current and an inactivating sodium current, dominate the firing behavior. We simulated the electrical

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Rose, L. J., and H. O'Connell. "UV Light Inactivation of Bacterial Biothreat Agents." Applied and Environmental Microbiology 75, no. 9 (2009): 2987–90. http://dx.doi.org/10.1128/aem.02180-08.

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ABSTRACT Seven species of bacterial biothreat agents were tested for susceptibility to UV light (254 nm). All gram-negative organisms tested required <12 mJ/cm2 for a 4-log10 reduction in viability (inactivation). Tailing off of the B. anthracis spore inactivation curves began close to the 2-log10 inactivation point, with a fluence of approximately 40 mJ/cm2, and 3-log10 inactivation still was not achieved with a fluence of 120 mJ/cm2.

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Gilboa-Ron, A., A. Rogel, and E. Hanski. "Bordetella pertussis adenylate cyclase inactivation by the host cell." Biochemical Journal 262, no. 1 (1989): 25–31. http://dx.doi.org/10.1042/bj2620025.

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Bordetella pertussis produces a calmodulin-dependent adenylate cyclase (AC) which acts as a toxin capable of penetrating eukaryotic cells and generating high levels of intracellular cyclic AMP. Transfer of target cells into B. pertussis AC-free medium leads to a rapid decay in the intracellular AC activity, implying that the invasive enzyme is unstable in the host cytoplasm. We report here that treatment of human lymphocytes with a glycolysis inhibitor and an uncoupler of oxidative phosphorylation completely blocked the intracellular inactivation of B. pertussis AC. Lymphocyte lysates inactiva

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40

Chisari, Francis V. "Intracellular Inactivation of the Hepatitis B Virus by Inflammatory Cytokines." Kanzo 39, supl2 (1998): 57. http://dx.doi.org/10.2957/kanzo.39.supl2_57.

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Jiang, Yuan, Albert Wingnang Leung, Xinna Wang, Hongwei Zhang, and Chuanshan Xu. "Inactivation of Staphylococcus aureus by photodynamic action of hypocrellin B." Photodiagnosis and Photodynamic Therapy 10, no. 4 (2013): 600–606. http://dx.doi.org/10.1016/j.pdpdt.2013.06.004.

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Banik, Gregory M., and Richard B. Silverman. "Mechanism of inactivation of monoamine oxidase B by (aminomethyl)trimethylsilane." Journal of the American Chemical Society 112, no. 11 (1990): 4499–507. http://dx.doi.org/10.1021/ja00167a057.

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Lu, Xingliang, Marı́a Rodrı́guez, Wenxin Gu, and Richard B. Silverman. "Inactivation of mitochondrial monoamine oxidase B by methylthio-substituted benzylamines." Bioorganic & Medicinal Chemistry 11, no. 20 (2003): 4423–30. http://dx.doi.org/10.1016/s0968-0896(03)00486-3.

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Abe, Tomoki, Katsuya Hirasaka, and Takeshi Nikawa. "Involvement of Cbl-b-mediated macrophage inactivation in insulin resistance." World Journal of Diabetes 8, no. 3 (2017): 97. http://dx.doi.org/10.4239/wjd.v8.i3.97.

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Canbay, Ali, Hajime Higuchi, Maria E. Guicciardi, et al. "Cathepsin B inactivation attenuates hepatic apoptosis and fibrosis during cholestasis." Gastroenterology 124, no. 4 (2003): A689. http://dx.doi.org/10.1016/s0016-5085(03)83483-2.

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Yamamoto, F., K. Maeno, S. Shibata, M. Iinuma, A. Miyama, and Y. Kawamoto. "Inactivation of Influenza B Virus by Normal Guinea-pig Serum." Journal of General Virology 68, no. 4 (1987): 1135–41. http://dx.doi.org/10.1099/0022-1317-68-4-1135.

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Riccio, L. G. C., M. Jeljeli, P. Santulli, et al. "B lymphocytes inactivation by Ibrutinib limits endometriosis progression in mice." Human Reproduction 34, no. 7 (2019): 1225–34. http://dx.doi.org/10.1093/humrep/dez071.

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Abstract:

Abstract STUDY QUESTION What are the effects of B lymphocyte inactivation or depletion on the progression of endometriosis? SUMMARY ANSWER Skewing activated B cells toward regulatory B cells (Bregs) by Bruton’s tyrosine kinase (Btk) inhibition using Ibrutinib prevents endometriosis progression in mice while B cell depletion using an anti-CD20 antibody has no effect. WHAT IS KNOWN ALREADY A polyclonal activation of B cells and the presence of anti-endometrial autoantibodies have been described in a large proportion of women with endometriosis though their exact role in the disease mechanisms re

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Canbay, Ali, Maria Eugenia Guicciardi, Hajime Higuchi, et al. "Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis." Journal of Clinical Investigation 114, no. 1 (2004): 142. http://dx.doi.org/10.1172/jci17740c1.

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Canbay, Ali, Maria Eugenia Guicciardi, Hajime Higuchi, et al. "Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis." Journal of Clinical Investigation 112, no. 2 (2003): 152–59. http://dx.doi.org/10.1172/jci200317740.

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Canbay, A. "Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis." Journal of Clinical Investigation 114, no. 1 (2004): 142. http://dx.doi.org/10.1172/jci200417740c1.

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