Academic literature on the topic 'Inbreeding load'

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Journal articles on the topic "Inbreeding load"

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Nagy, István, and Thi Anh Nguyen. "Characterizing and Eliminating the Inbreeding Load." Veterinary Sciences 11, no. 1 (2023): 8. http://dx.doi.org/10.3390/vetsci11010008.

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The authors evaluated the relevant literature related to purging, which is the interaction between selection and inbreeding in which the population may eliminate its inbreeding load at least partially. According to the relevant literature, the inbreeding load and the process of purging were evaluated via pedigree methods based on ancestral inbreeding, the inbreeding–purging model, and expressed opportunity of purging, along with genomic methods. Most ancestral inbreeding-related studies were performed in zoos, where only a small proportion of the studied populations show signs of purging. The
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CHARLESWORTH, BRIAN. "The effect of synergistic epistasis on the inbreeding load." Genetical Research 71, no. 1 (1998): 85–89. http://dx.doi.org/10.1017/s0016672398003140.

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The magnitude of inbreeding depression in Drosophila melanogaster appears too large to be accounted for by mutational load with multiplicative fitness interactions among loci, if current estimates of mutation and selection parameters are valid. One possible explanation for this discrepancy is synergistic epistasis among the fitness effects of deleterious mutations. A simple model of the effect of synergistic epistasis on the inbreeding load is developed. This model is used to show that deleterious mutations could account for the Drosophila data on the effects of inbreeding on components of fit
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BATAILLON, THOMAS, and MARK KIRKPATRICK. "Inbreeding depression due to mildly deleterious mutations in finite populations: size does matter." Genetical Research 75, no. 1 (2000): 75–81. http://dx.doi.org/10.1017/s0016672399004048.

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We studied the effects of population size on the inbreeding depression and genetic load caused by deleterious mutations at a single locus. Analysis shows how the inbreeding depression decreases as population size becomes smaller and/or the rate of inbreeding increases. This pattern contrasts with that for the load, which increases as population size becomes smaller but decreases as inbreeding rate goes up. The depression and load both approach asymptotic limits when the population size becomes very large or very small. Numerical results show that the transition between the small and the large
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Wang, Dongfeng, Hosein Salehian-Dehkordi, Langda Suo, and Fenghua Lv. "Impacts of Population Size and Domestication Process on Genetic Diversity and Genetic Load in Genus Ovis." Genes 14, no. 10 (2023): 1977. http://dx.doi.org/10.3390/genes14101977.

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In theoretical biology, a prevailing hypothesis posits a profound interconnection between effective population size (Ne), genetic diversity, inbreeding, and genetic load. The domestication and improvement processes are believed to be pivotal in diminishing genetic diversity while elevating levels of inbreeding and increasing genetic load. In this study, we performed a whole genome analysis to quantity genetic diversity, inbreeding, and genetic load across seven wild Ovis species and five domesticated sheep breeds. Our research demonstrates that the genetic load and diversity of species in the
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Latter, B. D., J. C. Mulley, D. Reid, and L. Pascoe. "Reduced genetic load revealed by slow inbreeding in Drosophila melanogaster." Genetics 139, no. 1 (1995): 287–97. http://dx.doi.org/10.1093/genetics/139.1.287.

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Abstract The rate of decline in reproductive fitness in populations of Drosophila melanogaster inbred at an initial rate of approximately 1% per generation has been investigated under both competitive and noncompetitive conditions. Breeding population size was variable in the inbred lines with an estimated harmonic mean of 66.7 +/- 2.2. Of the 60 lines maintained without reserves, 75% survived a period of 210 generations of slow inbreeding and were then rapidly inbred by full-sib mating to near-homozygosity. The initial rate of inbreeding was estimated to be 0.96 +/- 0.16% per generation, corr
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Guillaume, Frédéric, and Nicolas Perrin. "Joint Evolution of Dispersal and Inbreeding Load." Genetics 173, no. 1 (2006): 497–509. http://dx.doi.org/10.1534/genetics.105.046847.

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Nietlisbach, Pirmin, Stefanie Muff, Jane M. Reid, Michael C. Whitlock, and Lukas F. Keller. "Nonequivalent lethal equivalents: Models and inbreeding metrics for unbiased estimation of inbreeding load." Evolutionary Applications 12, no. 2 (2018): 266–79. http://dx.doi.org/10.1111/eva.12713.

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Fox, C. W., K. L. Scheibly, B. P. Smith, and W. G. Wallin. "Inbreeding depression in two seed-feeding beetles, Callosobruchus maculatus and Stator limbatus (Coleoptera: Chrysomelidae)." Bulletin of Entomological Research 97, no. 1 (2007): 49–54. http://dx.doi.org/10.1017/s0007485307004737.

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AbstractInbreeding depression is well documented in insects but the degree to which inbreeding depression varies among populations within species, and among traits within populations, is poorly studied in insects other than Drosophila. Inbreeding depression was examined in two long-term laboratory colonies of the seed beetle, Callosobruchus maculatus (Fabricius), which are used frequently as models for experiments in ecology, evolution and behaviour. Inbreeding depression in these laboratory colonies are compared with one recently field-collected population of a different seed beetle, Stator l
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Willis, John H. "Inbreeding Load, Average Dominance and the Mutation Rate for Mildly Deleterious Alleles in Mimulus guttatus." Genetics 153, no. 4 (1999): 1885–98. http://dx.doi.org/10.1093/genetics/153.4.1885.

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Abstract The goal of this study is to provide information on the genetics of inbreeding depression in a primarily outcrossing population of Mimulus guttatus. Previous studies of this population indicate that there is tremendous inbreeding depression for nearly every fitness component and that almost all of this inbreeding depression is due to mildly deleterious alleles rather than recessive lethals or steriles. In this article I assayed the homozygous and heterozygous fitnesses of 184 highly inbred lines extracted from a natural population. Natural selection during the five generations of self
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Glémin, Sylvain, Thomas Bataillon, Joëlle Ronfort, Agnès Mignot, and Isabelle Olivieri. "Inbreeding Depression in Small Populations of Self-Incompatible Plants." Genetics 159, no. 3 (2001): 1217–29. http://dx.doi.org/10.1093/genetics/159.3.1217.

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Abstract Self-incompatibility (SI) is a widespread mechanism that prevents inbreeding in flowering plants. In many species, SI is controlled by a single locus (the S locus) where numerous alleles are maintained by negative frequency-dependent selection. Inbreeding depression, the decline in fitness of selfed individuals compared to outcrossed ones, is an essential factor in the evolution of SI systems. Conversely, breeding systems influence levels of inbreeding depression. Little is known about the joint effect of SI and drift on inbreeding depression. Here we studied, using a two-locus model,
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Dissertations / Theses on the topic "Inbreeding load"

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Antonios, Simona. "Méthodes basées sur la généalogie pour partitionner le gain génétique et le fardeau génétique chez les ovins laitiers." Electronic Thesis or Diss., Université de Toulouse (2023-....), 2024. http://www.theses.fr/2024TLSEP099.

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Cette thèse explore des méthodes basées sur la généalogie pour partitionner le gain génétique et le fardeau génétique (FG) dans les races ovines laitières françaises : Lacaune (LAC), Basco-Béarnaise (BB), Manech Tête Noire (MTN) et Manech Tête Rousse (MTR). Le Chapitre 2 a utilisé une analyse rétrospective pour affiner la partition de la tendance génétique dans les échantillonnages mendéliens par catégorie d'animaux définies par le sexe et par la voie de sélection, ainsi que pour caractériser les contributions génétiques à long terme. Nous avons analysé le gain génétique pour la production lai
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Book chapters on the topic "Inbreeding load"

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Garg, Meenu, Pragyanshree Nayak, Alok Kumar Singh, and Ashwini Kumar Ray. "Inbreeding and Genetic Load and Role of Ecogenomics in Landscape Genetic Restoration." In Plant Ecogenomics. Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003282006-11.

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Rowe, Graham, Michael Sweet, and Trevor J. C. Beebee. "Conservation genetics." In An Introduction to Molecular Ecology. Oxford University Press, 2017. http://dx.doi.org/10.1093/hesc/9780198716990.003.0010.

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The chapter looks into conservation genetics as a method used to mitigate extinction. It explains how molecular genetics is used in conservation biology. Molecular systemics are great assets in wildlife forensic investigations. PCR technology enables genetic studies to be conducted on rare species. The chapter notes careful evaluation is needed as neutral estimates of genetic diversity sometimes differ from measures of adaptive variation. Next, the chapter explores the basis and impact of inbreeding and captive breeding in relation to the genetic load of smaller populations. The chapter expoun
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Goodenough, Anne E., and Adam G. Hart. "Ex Situ Conservation." In Applied Ecology. Oxford University Press, 2017. http://dx.doi.org/10.1093/hesc/9780198723288.003.0016.

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This chapter looks into ex situ conservation. It acknowledges that in situ conservation techniques might be needed if a successful ex situ conservation programme, which is termed reintroduction, is achieved. The chapter explores the subdivisions of ex situ conservation: intensive or general captive breeding programmes and gene banks. Additionally, it discusses the example of the Lord Howe Island Group's ex situ conservation action on the Lord Howe Island stick insect. The chapter notes the significance of collection, transport, captive breeding, reintroduction, supplementation, and reinforceme
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Conference papers on the topic "Inbreeding load"

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Varona, L., D. López-Carbonell, H. Srihi, et al. "183. Genetic variability in the individual inbreeding load: genomic prediction for artificial purging." In World Congress on Genetics Applied to Livestock Production. Wageningen Academic Publishers, 2022. http://dx.doi.org/10.3920/978-90-8686-940-4_183.

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