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1

Salmon, Harold A., Simon Briscoe, Graham R. Foster, and Martin A. Pitt. "Targeted vs opportunistic screening for viral hepatitis among UK migrant communities: a cost-effectiveness analysis." British Journal of Healthcare Management 27, no. 3 (2021): 90–98. http://dx.doi.org/10.12968/bjhc.2020.0077.

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Worldwide eradication of chronic hepatitis B and C viruses by 2030 is a stated goal of the World Health Organization, UK government and the European Union. This study investigated the cost-effectiveness of targeted screening vs opportunistic screening for hepatitis B and C among migrant populations in the UK. Results of a previous clinical trial (HepFREE) carried out in London and Bradford were used to develop a combined decision tree and Markov simulation model. Despite a low response to invitations for vaccination, and a heterogeneous level of response between communities of different ethnic
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Naroditskiy, Victor, Sebastian Stein, Mirco Tonin, Long Tran-Thanh, Michael Vlassopoulos, and Nicholas Jennings. "Referral Incentives in Crowdfunding." Proceedings of the AAAI Conference on Human Computation and Crowdsourcing 2 (September 5, 2014): 171–83. http://dx.doi.org/10.1609/hcomp.v2i1.13147.

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Word-of-mouth, referral, or viral marketing is a highly sought-after way of advertising. In this paper, we investigate whether such marketing can be encouraged through incentive mechanisms, thus allowing an organisation to effectively crowdsource their marketing. Specifically, we undertake a field experiment that compares several mechanisms for incentivising social media shares in support of a charitable cause. Our experiment takes place on a website promoting a fundraising drive by a large cancer research charity. Site visitors who sign up to support the cause are asked to spread the word abo
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3

Mkandawire, James, Fred M. Ssewamala, Judith A. Hahn, et al. "Economic and relationship-strengthening intervention to reduce alcohol use in couples living with HIV in Malawi: a study protocol for a randomised controlled trial of Mlambe." BMJ Open 15, no. 2 (2025): e097247. https://doi.org/10.1136/bmjopen-2024-097247.

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IntroductionHeavy alcohol use has the potential to derail progress towards UNAIDS 95-95-95 targets for countries in sub-Saharan Africa (SSA). Within couples, alcohol use is closely linked with factors such as intimate partner violence and economic insecurity and can result in poor adherence to antiretroviral therapy (ART) and HIV clinical outcomes. We hypothesise that a combined economic and relationship intervention for couples that builds on the prior success of standalone economic and relationship-strengthening interventions will be efficacious for improving HIV clinical outcomes and reduci
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Tang, Shaojie, and Jing Yuan. "Submodular Optimization beyond Nonnegativity: Adaptive Seed Selection in Incentivized Social Advertising." Proceedings of the International AAAI Conference on Web and Social Media 18 (May 28, 2024): 1490–502. http://dx.doi.org/10.1609/icwsm.v18i1.31404.

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Social advertising, also known as social promotion, is a method of promoting products or ideas through the use of influential individuals, known as ``seeds,'' on online social networks. Advertisers and platforms are the main players in this ecosystem, with platforms selling viral engagements, such as ``likes,'' to advertisers by inserting ads into the feeds of seeds. Seeds are given monetary incentives by the platform in exchange for their participation in the campaign, and when a follower of a seed engages with an ad, the platform receives payment from the advertiser. Specifically, at the beg
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Chang, Xueqin, Xiangyu Ke, Lu Chen, Congcong Ge, Ziheng Wei, and Yunjun Gao. "Host Profit Maximization: Leveraging Performance Incentives and User Flexibility." Proceedings of the VLDB Endowment 17, no. 1 (2023): 51–64. http://dx.doi.org/10.14778/3617838.3617843.

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The social network host has knowledge of the network structure and user characteristics and can earn a profit by providing merchants with viral marketing campaigns. We investigate the problem of host profit maximization by leveraging performance incentives and user flexibility. To incentivize the host's performance, we propose setting a desired influence threshold that would allow the host to receive full payment, with the possibility of a small bonus for exceeding the threshold. Unlike existing works that assume a user's choice is frozen once they are activated, we introduce the Dynamic State
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Stebbing, Justin, Ginés Sánchez Nievas, Marco Falcone, et al. "JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality." Science Advances 7, no. 1 (2020): eabe4724. http://dx.doi.org/10.1126/sciadv.abe4724.

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Using AI, we identified baricitinib as having antiviral and anticytokine efficacy. We now show a 71% (95% CI 0.15 to 0.58) mortality benefit in 83 patients with moderate-severe SARS-CoV-2 pneumonia with few drug-induced adverse events, including a large elderly cohort (median age, 81 years). An additional 48 cases with mild-moderate pneumonia recovered uneventfully. Using organotypic 3D cultures of primary human liver cells, we demonstrate that interferon-α2 increases ACE2 expression and SARS-CoV-2 infectivity in parenchymal cells by greater than fivefold. RNA-seq reveals gene response signatu
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7

Sirpal, Sanjeev, and Natasha Chandok. "Barriers to hepatitis C diagnosis and treatment in the DAA era: Preliminary results of a community-based survey of primary care practitioners." Canadian Liver Journal 5, no. 1 (2022): 96–100. http://dx.doi.org/10.3138/canlivj-2021-0032.

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Notwithstanding the groundbreaking achievement of hepatitis C curative treatment with direct-acting antiviral therapies, Canada faces an uphill battle in reaching the 2030 goal of viral elimination set forth by the World Health Organization, a goal made more difficult by the COVID-19 pandemic. There is limited understanding of the diagnostic and treatment barriers, and challenges in linkage to care in Canada, especially as it pertains to primary care providers in a community context. Therefore, in this article, the authors conducted a survey study to evaluate the following factors: primary car
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8

Amao, Lateefat K., David I. Olatunji, Gordon Igbodo, et al. "Trend and enhanced surveillance of Monkeypox during COVID-19 pandemic in Nigeria." Journal of Public Health in Africa 13, no. 1 (2022): 6. http://dx.doi.org/10.4102/jphia.v13i1.401.

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Monkeypox (MPX) is a viral zoonosis with lesions like smallpox. Though rare in Nigeria, sporadic outbreaks have been reported in 17 states since September 2017. Unfortunately, the COVID-19 pandemic has further reduced surveillance and reporting of MPX disease. This study seeks to assess the effect of an enhanced surveillance approach to detect MPX cases and measure the cumulative incidence of MPX in priority states in Nigeria. We identified three priority states (Rivers, Delta and Bayelsa) and their Local Government Areas (LGAs) based on previous disease incidence. We also identified, trained,
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9

Rao, Sudheendra, Alejo A. Morales, and Damien D. Pearse. "The Comparative Utility of Viromer RED and Lipofectamine for Transient Gene Introduction into Glial Cells." BioMed Research International 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/458624.

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The introduction of genes into glial cells for mechanistic studies of cell function and as a therapeutic for gene delivery is an expanding field. Though viral vector based systems do exhibit good delivery efficiency and long-term production of the transgene, the need for transient gene expression, broad and rapid gene setup methodologies, and safety concerns regardingin vivoapplication still incentivize research into the use of nonviral gene delivery methods. In the current study, aviral gene delivery vectors based upon cationic lipid (Lipofectamine 3000) lipoplex or polyethylenimine (Viromer
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10

Wey, Arkady, Alan Champneys, Rosemary J. Dyson, Nisreen A. Alwan, and Mary Barker. "The benefits of peer transparency in safe workplace operation post pandemic lockdown." Journal of The Royal Society Interface 18, no. 174 (2021): 20200617. http://dx.doi.org/10.1098/rsif.2020.0617.

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The benefits of different levels of engagement with test, trace and isolate procedures are investigated for a pandemic in which there is little population immunity, in terms of productivity and public health. Simple mathematical modelling is used in the context of a single, relatively closed workplace such as a factory or back-office where, in normal operation, each worker has lengthy interactions with a fixed set of colleagues. A discrete-time SEIR model on a fixed interaction graph is simulated with parameters that are motivated by the recent COVID-19 pandemic in the UK during a post-peak ph
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11

Naskar, Partha, Biki Digar, Samadrita Ghosh, and Pitu Kundu. "Determining Interconnecting Role of Social Media Marketing Strategies: A Young Population Study." International Journal of Marketing and Business Communication 14, no. 1 (2025): 15–30. https://doi.org/10.21863/ijmbc/2025.14.1.002.

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In the rapidly evolving digitalised era organisations and businesses are proactively adopting technological developments and innovative relationships in the marketing sphere. The literature of the study revolves around the key aspects of e-marketing strategies and customer loyalty, marketing influencers in social network, digital marketing and buyer’s behaviour of youth, social media campaign in customer buying pattern, social media network and viral marketing for reinventing effective marketing strategies in the marketing arena. The paper focuses to gauge the impact of social media marketing
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Tardiolo, Giuseppe, Pina Brianti, Daniela Sapienza, et al. "Are We Paving the Way to Dig Out of the “Pandemic Hole”? A Narrative Review on SARS-CoV-2 Vaccination: From Animal Models to Human Immunization." Medical Sciences 9, no. 3 (2021): 53. http://dx.doi.org/10.3390/medsci9030053.

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The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new pathogen agent causing the coronavirus infectious disease (COVID-19). This novel virus originated the most challenging pandemic in this century, causing economic and social upheaval internationally. The extreme infectiousness and high mortality rates incentivized the development of vaccines to control this pandemic to prevent further morbidity and mortality. This international scenario led academic scientists, industries, and governments to work and collaborate strongly to make a portfolio of vaccines available at an unp
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13

Raghoebar, Sanne, Joyce Delnoij, Bart A. Kamphorst, and Henk Broekhuizen. "Exposure to images showing (non)adherence to physical distancing rules: Effect on adherence behavior and perceived social norms." PLOS ONE 17, no. 11 (2022): e0276936. http://dx.doi.org/10.1371/journal.pone.0276936.

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Introduction Adherence to behavioral measures such as physical distancing are key to mitigating the effects of viral pandemics such as the COVID-19 pandemic. Adherence depends in part on people’s perception of what others do (descriptive norms) or approve of (injunctive norms). This study examines the effects that exposure to images depicting people following or breaking physical distancing rules have on perceptions of descriptive and injunctive norms and subsequent adherence behavior. Methods An online between-subjects experiment (n = 315) was conducted, in which participants were exposed to
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14

Saad, Ezzat, and Claire Kamoun. "Deployment and Assessment of a Virtual Coaching Platform to Support Healthy Habits and Whole Health for Vulnerable People Living with HIV." Iproceedings 5, no. 1 (2019): e15069. http://dx.doi.org/10.2196/15069.

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Background Office of Health and Human Services of Rhode Island (0HHS-RI) provides care to the most vulnerable people in the state living with HIV. While most of their clients achieve viral load suppression, the majority of these individuals still lack the support they need to tackle mental health issues, manage comorbidities, be physically active, and address other social determinants of Health. Digital health technologies have demonstrated value to provide this support and help people manage whole health. Digital platforms can deliver tailored health interventions and improved outcomes for pe
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15

Ortmann, Julia, Jana-Kristin Heise, Irina Janzen, et al. "Suitability and user acceptance of the eResearch system “Prospective Monitoring and Management App (PIA)”—The example of an epidemiological study on infectious diseases." PLOS ONE 18, no. 1 (2023): e0279969. http://dx.doi.org/10.1371/journal.pone.0279969.

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Background The eResearch system “Prospective Monitoring and Management App (PIA)” allows researchers to implement questionnaires on any topic and to manage biosamples. Currently, we use PIA in the longitudinal study ZIFCO (Integrated DZIF Infection Cohort within the German National Cohort) in Hannover (Germany) to investigate e.g. associations of risk factors and infectious diseases. Our aim was to assess user acceptance and compliance to determine suitability of PIA for epidemiological research on transient infectious diseases. Methods ZIFCO participants used PIA to answer weekly questionnair
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16

Dombrowski, Julia C., Sean R. Galagan, Meena Ramchandani, et al. "HIV Care for Patients With Complex Needs: A Controlled Evaluation of a Walk-In, Incentivized Care Model." Open Forum Infectious Diseases 6, no. 7 (2019). http://dx.doi.org/10.1093/ofid/ofz294.

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Abstract Background New approaches are needed to provide care to persons with HIV who do not engage in conventionally organized HIV clinics. The Max Clinic in Seattle, Washington, is a walk-in, incentivized HIV care model located in a public health STD clinic that provides care in collaboration with a comprehensive HIV primary care clinic (the Madison Clinic). Methods We compared outcomes in the first 50 patients enrolled in Max Clinic and 100 randomly selected matched Madison Clinic control patients; patients in both groups were virally unsuppressed (viral load [VL] >200 copies/mL) at
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17

Chuai, Yuwei, and Jichang Zhao. "Anger can make fake news viral online." Frontiers in Physics 10 (August 22, 2022). http://dx.doi.org/10.3389/fphy.2022.970174.

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Fake news that manipulates political elections, strikes financial systems, and even incites riots is more viral than real news online, resulting in unstable societies and buffeted democracy. While factor that drives the viral spread of fake news is rarely explored. In this study, it is unexpectedly found that the easier contagion of fake news online is positively associated with the greater anger it carries. The same results in Twitter and Weibo indicate that this correlation is independent of the platform. Moreover, mutations in emotions like increasing anger will progressively speed up the i
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Hale, Jonathan F., Shellynea Reynolds, Heather R. Kates, et al. "Cannabis use is associated with a lower likelihood of presence of HIV drug resistance mutations in a retrospective cohort of adults with HIV." NeuroImmune Pharmacology and Therapeutics, February 10, 2025. https://doi.org/10.1515/nipt-2024-0010.

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Abstract Objectives A significant clinical concern in the era of Pre-Exposure Prophylaxis (PrEP) is the increased incidence of HIV Anti-Retroviral Drug Resistance Mutations (ARV-DRM). Previous research has indicated that there is an association between substance use and failed viral suppression, which can lead to ARV-DRM. The goal of this retrospective study was to investigate whether substance use as determined by at least one positive urinalysis screen is associated with increased/decreased odds of having a ARV-DRM. Methods This study used firth logistic regression analyses of data retrieved
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19

Ssewamala, Fred M., John A. Sauceda, Rachel Brathwaite, et al. "Suubi + Adherence4Youth: a study protocol to optimize the Suubi Intervention for Adherence to HIV treatment for youth living with HIV in Uganda." BMC Public Health 23, no. 1 (2023). http://dx.doi.org/10.1186/s12889-023-15564-4.

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Abstract Background Suubi is an evidenced based multi-component intervention that targets psychosocial and economic hardships to improve ART adherence, viral suppression, mental health, family financial stability, and family cohesion for adolescents living with HIV (ALHIV) in Uganda. Suubi was originally tested as a combined package of four components: 1) Financial Literacy Training; 2) incentivized matched Youth Savings Accounts with income-generating activities; 3) a manualized and visual-based intervention for ART adherence and stigma reduction; and 4) engagement with HIV treatment-experien
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20

Amao, Lateefat Kikelomo, David Idowu Olatunji, Gordon Igbodo, et al. "Trend and enhanced surveillance of Monkeypox during COVID-19 pandemic in Nigeria." Journal of Public Health in Africa 13, no. 1 (2022). http://dx.doi.org/10.4081/jphia.2022.2184.

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Monkeypox (MPX) is a viral zoonosis with lesions like smallpox. Though rare in Nigeria, sporadic outbreaks have been reported in 17 states since September 2017. Unfortunately, the COVID-19 pandemic has further reduced surveillance and reporting of MPX disease. This study seeks to assess the effect of an enhanced surveillance approach to detect MPX cases and measure the cumulative incidence of MPX in priority states in Nigeria. We identified three priority states (Rivers, Delta and Bayelsa) and their Local Government Areas (LGAs) based on previous disease incidence. We also identified, trained,
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21

de Barra, Mícheál, Kawthar Hakimy, and Marijn de Bruin. "Signalling need for care: A neglected functional role of medical treatment." Evolution, Medicine, and Public Health, August 14, 2023. http://dx.doi.org/10.1093/emph/eoad024.

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Abstract While the primary goals of medical treatment are typically to shorten illness or relieve symptoms, we explore the idea that an important additional goal for some patients is to communicate need. Drawing on signalling theory, we argue that undergoing treatments can help patients legitimize their illness and thereby enable access to crucial support during convalescence. Four pre-registered within-subjects experiments (n = 874) show that participants are more inclined to provide care to people who undergo treatment, especially when that treatment is painful. Results show this incentivize
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Ssewamala, Fred M., Ozge Sensoy Bahar, Proscovia Nabunya, et al. "Suubi+Adherence-Round 2: A study protocol to examine the longitudinal HIV treatment adherence among youth living with HIV transitioning into young adulthood in Southern Uganda." BMC Public Health 21, no. 1 (2021). http://dx.doi.org/10.1186/s12889-021-10202-3.

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Abstract Background Youth living with HIV (YLHIV) in Sub-Saharan African (SSA) are less likely to adhere to antiretroviral therapy (ART) and other health-related regimens. As a consequence, YLHIV are not only at risk for health problems and mental health comorbidities, but are also at risk for cognitive deficits, including in areas of memory and executive functioning. The Suubi+Adherence study followed 702 adolescents (10-16 years of age) receiving bolstered standard of care and a family economic empowerment intervention comprising an incentivized youth financial savings account (YSA) augmente
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Gagnon, Marilou, Adrian Guta, Ross Upshur, Stuart J. Murray, and Vicky Bungay. ""It gets people through the door": a qualitative case study of the use of incentives in the care of people at risk or living with HIV in British Columbia, Canada." BMC Medical Ethics 21, no. 1 (2020). http://dx.doi.org/10.1186/s12910-020-00548-5.

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Abstract Background There has been growing interest in the use of incentives to increase the uptake of health-related behaviours and achieve desired health outcomes at the individual and population level. However, the use of incentives remains controversial for ethical reasons. An area in which incentives have been not only proposed but used is HIV prevention, testing, treatment and care—each one representing an interconnecting step in the "HIV Cascade." Methods The main objective of this qualitative case study was to document the experiences of health care and service providers tasked with ad
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Carlson, Kristen. "Highlights of the Issue." SuperIntelligence - Robotics - Safety & Alignment 2, no. 1 (2025). https://doi.org/10.70777/si.v2i1.14075.

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Highlights of the IssueKris Carlson, Publisher and Editor-in-ChiefOur second issue surveys state of the art of large language models (LLMs) with an emphasis on safety and value alignment. Superintelligence StrategyDan Hendrycks, Eric Schmidt, Alexandr WangSeeking Stability in the Competition for AI Advantage: Commentary on Superintelligence StrategyIskander Rehman, Karl P. Mueller, Michael J. Mazarr (RAND Corp.) I recommend the RAND Corp critique by knowledgeable military policy analysts over the Hendrycks et al. article. The RAND article is illuminative, incisive, covers Superintelligence Str
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Meese, James. "“It Belongs to the Internet”: Animal Images, Attribution Norms and the Politics of Amateur Media Production." M/C Journal 17, no. 2 (2014). http://dx.doi.org/10.5204/mcj.782.

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Cute pictures of animals feature as an inoffensive and adorable background to the contemporary online experience with cute content regularly shared on social media platforms. Indeed the demand for cuteness is so strong in the current cultural milieu that some animals become recognisable animal celebrities in the process (Hepola). However, despite the existence of this professionalisation in some sections of the cute economy, amateurs produce the majority of cute content that circulates online. This is largely because one of the central contributors to this steady stream of cute animal pictures
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Kustritz, Anne. "Transmedia Serial Narration: Crossroads of Media, Story, and Time." M/C Journal 21, no. 1 (2018). http://dx.doi.org/10.5204/mcj.1388.

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The concept of transmedia storyworlds unfolding across complex serial narrative structures has become increasingly important to the study of modern media industries and audience communities. Yet, the precise connections between transmedia networks, serial structures, and narrative processes often remain underdeveloped. The dispersion of potential story elements across a diverse collection of media platforms and technologies prompts questions concerning the function of seriality in the absence of fixed instalments, the meaning of narrative when plot is largely a personal construction of each au
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Sanchez Alonso, Jason. "Undue Burden the Medical School Application Process Places on Low-Income Latinos." Voices in Bioethics 9 (November 7, 2023). http://dx.doi.org/10.52214/vib.v9i.10166.

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Photo by Nathan Dumlao on Unsplash ABSTRACT The demographic of physicians in the United States has failed to include a proportionate population of Latinos in the United States. In what follows, I shall argue that the medical school admission process places an undue burden on low-income Latino applicants. Hence, the underrepresentation of Latinos in medical schools is an injustice. This injustice relates to the poor community health of the Latino community. Health disparities such as diabetes, HIV infection, and cancer mortality are higher amongst the Latino community. The current representatio
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