Relevant bibliographies by topics / Including platelet count

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Academic literature on the topic 'Including platelet count'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Including platelet count"

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Ajay, Kumar, Kumar Binay, Kanaujia Binita, and Raza Sahab. "A Retrospective Investigation to Study the Relationship between White Blood Cell Count (WBC), Which is Known Inflammatory Marker and Platelet Count (PLT) and its Parameters." International Journal of Toxicological and Pharmacological Research 13, no. 2 (2023): 76–82. https://doi.org/10.5281/zenodo.11280384.

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<strong>Aim:&nbsp;</strong>The aim of this study was to investigate the relationship between white blood cell count (WBC), which is known inflammatory marker and platelet count (PLT) and its parameters including mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT) and platelet- large cell ratio (P-LCR) in all clinical setting of leukocytosis in children.&nbsp;<strong>Methods:&nbsp;</strong>We performed a retrospective study on the children (2-18 years of age) coming to our laboratory Netaji Subhas Medical College &amp; Hospital, Bihta, Patna, Bihar for the period o
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Ruan, Changgeng, Yun Wu, Tokuhiro Okada, et al. "Studies on Reference Intervals for Platelet Counts in Three Cities in China and one in Japan." Thrombosis and Haemostasis 88, no. 07 (2002): 111–14. http://dx.doi.org/10.1055/s-0037-1613162.

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SummaryHematological parameters including platelet counts, etc. were determined in 1,140 healthy subjects living in four cities: Suzhou (Jiangsu Province), Chengdu (Sichuan Province) and Harbin (Heilongjang Province) in China, and Kobe in Japan. Then, the reference intervals for platelet counts were calculated and compared. The reference interval for platelet count of subjects aged between 18 and 60 years was 60-259 × 109/L in Suzhou and 52–202 × 109/L in Chengdu, and subjects with platelet counts of 100 × 109/L or less accounted for about 30% of the subjects examined in these cities. The refe
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Moffat, Karen A., Menaka Pai, Yang Liu, et al. "An evaluation of methods for determining reference intervals for light transmission platelet aggregation tests on samples with normal or reduced platelet counts." Thrombosis and Haemostasis 100, no. 07 (2008): 01–12. http://dx.doi.org/10.1160/th08-03-0183.

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SummaryLight transmission platelet aggregation tests are important for diagnosing platelet function defects. However, uncertainties exist about the best procedures to determine aggregation reference intervals. We investigated methods for determining reference intervals for light transmission aggregation tests, using the % maximal aggregation values for prospectively collected data on healthy control samples. Reference intervals for samples tested at 250 x 109 platelets/l were determined by mean ± 2 standard deviations and non-parametric analyses. To establish reference intervals for tests on t
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Chu, Ying-Hsia, William Nicholas Rose, William Nawrot, and Thomas J. Raife. "Pooled platelet concentrates provide a small benefit over single-donor platelets for patients with platelet refractoriness of any etiology." Journal of International Medical Research 49, no. 5 (2021): 030006052110167. http://dx.doi.org/10.1177/03000605211016748.

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Background At our institution, patients with platelet refractoriness (of any etiology) are sometimes switched from apheresis platelets to pooled platelets before human leukocyte antigen (HLA)-matched units become available. Study design and methods Seven patients were analyzed. Platelet counts were available from 57 single-unit transfusions (26 pooled, 31 apheresis). A mixed linear effects model was used and significance was determined using a likelihood ratio test. Results When analyzed as the only fixed effect in the model, the use of pooled versus single-donor units and time from transfusio
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Farner, Beate, Hartmut Kroll, Thomas Kohlmann, Theodore E. Warkentin, Petra Eichler, and Andreas Greinacher. "Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis." Thrombosis and Haemostasis 94, no. 07 (2005): 132–35. http://dx.doi.org/10.1160/th04-12-0825.

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SummaryImmune mediated heparin induced thrombocytopenia (HIT) is a prothrombotic adverse effect of heparin. However, only a subgroup of patients with HIT develops thromboembolic complications. We aimed to identify risk factors for developing HITassociated thrombosis. We analyzed a registry of patients with clinical suspicion of HIT who tested positive using a sensitive functional assay. Patient information was obtained by a standardized questionnaire. By multivariate analysis the association of age, gender, type of patient population, and magnitude of the platelet count decline with the freque
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Hirashima, Yutaka, Hideo Hamada, Masanori Kurimoto, Hideki Origasa, and Shunro Endo. "Decrease in platelet count as an independent risk factor for symptomatic vasospasm following aneurysmal subarachnoid hemorrhage." Journal of Neurosurgery 102, no. 5 (2005): 882–87. http://dx.doi.org/10.3171/jns.2005.102.5.0882.

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Object. Increased platelet consumption is expected in patients with cerebral vasospasm, according to data from clinical and experimental studies. The authors investigated sequential changes in platelet counts in patients with subarachnoid hemorrhage (SAH) and the difference in platelet consumption between patients with and those without symptomatic vasospasm (SV). Variables related to platelet count as well as other clinical and radiological variables were analyzed as independent predictors of SV. Methods. One hundred consecutive patients who had undergone surgery within 48 hours after SAH ons
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Khan, Sunia Qasuria, Muhammad Kaleem Khan, Yasar Mehmood Yousafzai, et al. "Platelet-Lymphocyte Ratio Dynamics and Severity Correlation in COVID-19: Insights from Platelet Count Variations." Journal of Saidu Medical College, Swat 15, no. 1 (2025): 76–81. https://doi.org/10.52206/jsmc.2025.15.1.1000.

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Background: COVID-19, driven by the novel β-Coronavirus, significantly affects hematological parameters. Platelet count, Platelet-Lymphocyte and Neutrophil-Lymphocyte Ratios have been recommended as potential signs of disease severity. This study aimed to evaluate the relationship between platelet count, PLR, and the severity of COVID-19 in hospitalized patients.Objective: To assess the association of Platelet-Lymphocyte Ratios, platelet count, and disease severity in hospitalized COVID-19 patients and determine their potential as prognostic markers.Materials and Methods: In this prospective s
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Rana, Himanshu, and Mahvesh Sheikh. "ESTIMATION AND COMPARISON OF PLATELET COUNT: AUTOMATED ANALYZERVS MANUAL PERIPHERAL SMEAR METHOD." International Journal of Advanced Research 11, no. 08 (2023): 621–28. http://dx.doi.org/10.21474/ijar01/17430.

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Accurately assessing platelet counts holds paramount importance in the realm of diagnostics and treatment. The adoption of automated methods within the diagnostic landscape is steadily growing, attributed to their multifaceted benefits. Nonetheless, automated analyzers sometimes yield erroneous results, particularly in scenarios involving particles of comparable sizes or instances of light scattering. These encompass fragmented red blood cells (RBCs), microcytic RBCs, and the presence of oversized platelets or platelet clusters. In response, the manual estimation of platelet counts using Leish
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Frelinger, Andrew L., Anja J. Gerrits, Michelle A. Berny-Lang, et al. "Association Of Platelet Function Markers, Independent Of Platelet Count, With Bleeding Score In Patients With Immune Thrombocytopenia." Blood 122, no. 21 (2013): 3534. http://dx.doi.org/10.1182/blood.v122.21.3534.3534.

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Abstract Background Immune thrombocytopenia (ITP) patients with similarly low platelet counts differ in their tendency to bleed. Aim To determine if differences in platelet function in ITP patients with similarly low platelet counts partly account for the variation in bleeding tendency. Methods The relationship between bleeding scores and platelet function markers was investigated in a single center cross-sectional study of pediatric patients with ITP. Following informed consent, blood was collected from ITP patients and bleeding was graded using the Buchanan and Adix Score (J Pediatr 2002) at
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Arnold, Donald M., Jane C. Moore, James W. Smith, and John G. Kelton. "An Individual Platelet Count Set-Point in ITP: A Concept Learned from Patients with Mild Thrombocytopenia and a Good Response to IVIg or Corticosteroids." Blood 110, no. 11 (2007): 3926. http://dx.doi.org/10.1182/blood.v110.11.3926.3926.

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Abstract Background: Immune thrombocytopenic purpura (ITP) is a heterogeneous disease caused by both increased platelet destruction and decreased platelet production. Thrombocytopenia is typically severe, and in the absence of a sensitive and specific test, a platelet count response to intravenous immune globulin (IVIg) or corticosteroids is diagnostic. Patients with mild thrombocytopenia (platelets 50 – 150 × 109/L) may have ITP, non-immune thrombocytopenia or a low-normal platelet count. The diagnostic value of platelet autoantibodies for such patients is not known. Methods: We studied the p
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Books on the topic "Including platelet count"

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McDonald, Vickie, and Marie Scully. Anticoagulants and antithrombotics in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0051.

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Coagulation is best thought of using the cell-based model of coagulation. Patients commenced on heparin therapy should have their platelet count monitored early because of the risk of heparin-induced thrombocytopenia, which can occur on any type or dose of heparin. Emergency reversal of warfarin should be with prothrombin complex concentrate (containing factors II, VII, IX, and X) and not fresh frozen plasma. New oral anticoagulants have the advantage of predictable pharmacokinetics and do not require routine monitoring, but optimal reversal strategies for these agents are not clear. Thromboly
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Noris, Marina, and Tim Goodship. The patient with haemolytic uraemic syndrome/thrombotic thrombocytopenic purpura. Edited by Giuseppe Remuzzi. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0174.

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The patient who presents with microangiopathic haemolytic anaemia, thrombocytopenia, and evidence of acute kidney injury presents a diagnostic and management challenge. Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are two of the conditions that frequently present with this triad. They are characterized by low platelet count with normal or near-normal coagulation tests, anaemia, and signs of intravascular red cell fragmentation on blood films, and high LDH levels.HUS associated with shiga-like toxins produced usually by E.coli (typically O157 strains) may occu
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Book chapters on the topic "Including platelet count"

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Ciurea, Stefan O., and Ronald Hoffman. "Thrombocytosis." In Oxford Textbook of Medicine. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199204854.003.220310.

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Thrombocytosis describes a platelet count elevated above 450 × 10<sup>9</sup>/litre, which can be (1) primary—including essential thrombocythaemia, chronic myeloid leukaemia, polycythaemia vera and myelodysplastic syndromes; or (2) secondary—including iron deficiency, infection, blood loss, malignancy. Platelets are released from megakaryocytes, whose development is principally regulated by thrombopoietin. This is chiefly produced in the liver and binds to its receptor (c-Mpl) to cause activation via the JAK-STAT signalling pathway at different levels of the platelet production pathway, rangin
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Ogweno, Gordon, and Edwin Murungi. "Interplay between Platelet Dysfunction and Vascular Thrombosis in Traumatic Injury." In Advances in the Diagnosis and Management of Vascular Thrombosis [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.111758.

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Platelets halt bleeding accompanying traumatic injury by performing primary hemostasis to repair vascular leakage at injury sites. In trauma individuals, ex vivo platelet function tests often indicate impairment despite normal count. Moreover, incubation of platelets from normal non-traumatized individuals with plasma from trauma victims demonstrates impairment suggesting association with factors in circulation. Notably, not all trauma victims die from hemorrhage. Despite laboratory evidence of dysfunction, thrombotic vascular occlusions are persistent in trauma survivors as corroborated by po
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Becker, Richard C., and Frederick A. Spencer. "Platelet Antagonists." In Fibrinolytic and Antithrombotic Therapy. Oxford University Press, 2006. http://dx.doi.org/10.1093/oso/9780195155648.003.0035.

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Platelet antagonists play an important role in both primary and secondary prevention of atherothrombotic events. Despite their proven benefit, individual response (and protection) varies considerably, emphasizing the importance of developing monitoring tools (tested prospectively in clinical trials) that can better determine the degree of platelet inhibition that is both safe and effective. Platelet function studies were developed originally for the evaluation of patients with unexplained bleeding and have contributed greatly to the understanding, diagnosis, and management of hereditary abnorm
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Strauchen, James A. "Disorders of Platelets." In Diagnostic Histopathology of the Bone Marrow. Oxford University PressNew York, NY, 1996. http://dx.doi.org/10.1093/oso/9780195097566.003.0008.

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Abstract Thrombocytosis occurs as a reaction to hemorrhage, chronic blood loss and iron deficiency, chronic inflammatory and neoplastic disorders, and in association with primary hematologic disorders, including chronic granulocytic leukemia, the myeloproliferative disorders, and, rarely, the myelodysplastic syndromes (the 5q- syndrome). Bone marrow examination is commonly performed in patients with thrombocytosis in an effort to distinguish reactive thrombocytosis from thrombocytosis associated with myeloproliferative disease and primary hematologic disorders, which differ in therapeutic and
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Lazuardi Lutfan, Sanjaya Guardian Yoki, Candradewi Ika, and Holmner Åsa. "Automatic Platelets Counter for Supporting Dengue Case Detection in Primary Health Care in Indonesia." In Studies in Health Technology and Informatics. IOS Press, 2013. https://doi.org/10.3233/978-1-61499-289-9-585.

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Dengue fever is a major problem in many developing countries, including Indonesia. Laboratory examination is used to diagnose dengue infection and to monitor disease progression. Hematology tests, such as platelet count, are also used for timely recognition of the development of severe dengue. In primary health care centers platelet counting is typically performed manually, which is labor intensive and requires an experienced laboratory technician. To address this challenge, we have developed an automatic platelet counter for primary health care and resource-poor settings. The technology is ba
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Akerman, Michael, Ariel Anderson, and Ryan Norman. "Elective Abdominal Aortic Aneurysm With Epidural Analgesia." In Regional Anesthesia and Acute Pain Medicine, edited by Jinlei Li. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197518519.003.0045.

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Abstract Heparin induced thrombocytopenia (HIT) is an immune-mediated, low blood platelet count as a result of heparin administration. The clinical features, including the recovery of platelet count with discontinuation of heparin therapy and recurrent thrombocytopenia with repeat heparin challenge. After reviewing this chapter, the reader will learn about the different types of heparin induced thrombocytopenia (HIT), how to diagnose and manage HIT, how to manage an epidural catheter in patients who develop HIT and are being treated for it. This chapter also reviews some of the medications use
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Aruch, Daniel, and Ronald Hoffman. "Thrombocytosis and essential thrombocythaemia." In Oxford Textbook of Medicine, edited by Chris Hatton and Deborah Hay. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0518.

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The term thrombocytosis refers to a platelet count elevated above 450 × 10<sup>9</sup>/litre, which can be (1) primary—including essential thrombocythaemia, chronic myeloid leukaemia, polycythaemia vera, and myelodysplastic syndromes; or (2) secondary—including iron deficiency, infection, blood loss, and malignancy. Essential thrombocythaemia: aetiology—the JAK2 V617F missense mutation typical of polycythaemia vera is found in about 50% of cases. In addition, 10% of patients have a mutation in the thrombopoietin receptor gene, MPL, and 30% have a mutation in calreticulin (CALR). Approximately
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Reyna, Rolando. "Imaging in Dengue Fever." In Dengue Fever in a One Health Perspective - Latest Research and Recent Advances [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.109858.

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Dengue is a viral disease caused by a flavivirus transmitted by Aedes aegypti mosquitoes in tropical regions but has spread to regions of Europe, subtropical regions, and South America. The clinic is varied, so imaging methods are important before having a positive confirmatory test. Clinically, dengue is a disease that increases vascular permeability with loss of plasma and albumin, causing polyserotis. The most accessible imaging methods in the emergency room are chest radiography and abdominal ultrasound. Chest radiography shows that the most frequent finding is pleural effusion. Abdominal
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Strauchen, James A. "Chronic Myeloproliferative Disorders." In Diagnostic Histopathology of the Bone Marrow. Oxford University PressNew York, NY, 1996. http://dx.doi.org/10.1093/oso/9780195097566.003.0013.

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Abstract The chronic myeloproliferative disorders are clonal disorders of hematopoiesis characterized by proliferation of one or more hematopoietic cell lines, development of marrow fibrosis, and an increased incidence of acute granulocytic leukemia. The disorders usually considered in this group are polycythemia vera, myeloid metaplasia-myelofibrosis, and essential thrombocythemia. Polycythemia vera is a chronic myeloproliferative disorder characterized by increased red cell mass. Patients with polycythemia vera present with symptoms related to increased red cell mass, including plethora, ven
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Leontiev, Pavlo, Inna Torianyk, and Svitlana Kalinichenko. "PARAMETERS OF BLOOD AND ERYTHROCYTES AS MARKERS OF AGE OF OCCURRENCE OF HEMATOMAS IN LIVING PERSONS." In Modernization of research area: national prospects and European practices. Publishing House “Baltija Publishing”, 2022. http://dx.doi.org/10.30525/978-9934-26-221-0-15.

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The article deals with solution of the scientific-practical task of modern forensic medicine: substantiation for medicolegal assessment of prescription of formation of posttraumatic sub- and epidural haemorrhages in living persons. The purpose: to determine the age of hematoma in living persons by the parameters of functional changes in the blood system and erythrocyte hematopoiesis. Methodology of the study is based on general research methods of analysis of cytological results the haematological indices, which were the most available and effective ones in accelerated diagnosis of the prescri
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Conference papers on the topic "Including platelet count"

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Vidal, JR, and OR Vidal. "EVALUATION OF THE EFFICACY OF AN ARTIFICIAL INTELLIGENCE ALGORITHM FOR PREDICTING THE ESTIMATED VALUE OF PLATELET CONCENTRATE DURING APHERESIS." In Resumos do 55º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s2.8789.

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Objective: Artificial intelligence (AI) can enhance human health by providing predictions and recommendations based on clinical data. The aim of this study was to develop and evaluate the effectiveness of an AI algorithm for predicting the estimated value of platelet concentrate (PC) obtained by apheresis. Method: This was an applied study using data from 30 patients, including age, BMI, gender, complete blood count (hematocrit, blood type, platelets), number of cycles, apheresis time, processed blood volume, and platelet concentrate value. Linear regression in Python was used for platelet con
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Alzua, Brian, Mark Smith, and Yan Chen. "A Flow Cytometry Method for Characterizing Platelet Activation." In 2020 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/dmd2020-9070.

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Abstract Hemocompatibility testing is critical for assessing the safety of blood-contacting medical devices. Comprehensive hemocompatibility testing requires examining a wide range of possible adverse effects cause by direct or indirect blood contact, such as hemolysis, complement activation, and thrombus formation [1]. Moreover, these domains each encompass complex intercellular processes with many potential targets for analysis. For example, the current testing paradigm of platelet function may involve exposing the device to human whole blood and performing simple blood counts and/or macrosc
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Devi, Pinki, Ganapathi Bhat, and Harish S. Ahuja. "To Predict Success of Postapheresis Yield and Post–Autologous Transplant Engraftment Based on Preapheresis Peripheral Blood CD34+ Cell Counts: An Indian Scenario–Based Study." In Annual Conference of Indian Society of Medical and Paediatric Oncology (ISMPO). Thieme Medical and Scientific Publishers Pvt. Ltd., 2021. http://dx.doi.org/10.1055/s-0041-1735370.

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Abstract Introduction The use of hematopoietic stem cells for autologous and allogeneic transplantation has increased in the recent past significantly, due to introduction of newer chemotherapeutic drugs, immunological techniques, and better stem cell technology. Among the bone marrow and peripheral blood stem cells, collection of the latter being more convenient to the patient and associated with faster granulocyte and platelet engraftment has been known as preferred method for mobilization. Peripheral blood stem cells can be extracted from the autologous or allogeneic donor. Mobilization of
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Kehrel, B., L. Ballesian, R. Kokott, W. Stenzinger, K. J. Clemetson, and J. Van De Loo. "REVERSIBLE DEFICIENCY OF INTACT THROMBOSPONDIN AND MEMBRANE GLYCOPROTEIN Ia IN PLATELETS OF A PATIENT WITH A BLEEDING DISORDER." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644654.

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A 52 year old female patient with a severe bleeding tendency since the age of two was studied. Her history revealed recurrent petechial bleedings, two severe postoperative haemorrhagic episodes and intensivemenstrual bleedings which required blood transfusions. Coagulation studies ruled out any coagulation disorder including von Willebrand's disease. Platelet count and morphology(using light and electron microscopy) were normal. The patient had prolonged bleeding times (up to 15 min). Her platelets aggregated normally in response to ADP, arachidonic acid, thrombin, ionophore A 23187, epinephri
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Bussel, J. "FOR MODULATION AS A MEANS OF ELEVATING THE PLATELET COUNT IN ITP." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644761.

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ITP is an autoantibody-mediated disease which would logically be treated by decreasing the level of autoantibody. However, the most exciting developments in understanding the pathophysiology of the thrombocytopenia and its treatment involve a better understanding of the MPS FcR system and ways in which it can be modulated. This work has focussed on phagocytic paralysis or FcR blockade (FcRBl): the slowing of destruction of antibody-coated platelets despite the persistent presence of antibody on the surface of the platelet.Several areas have been explored in learning about the MPS system. Inves
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Chesney, C. M., and R. H. Lands. "THROMBOSIS IN PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643927.

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Heparin induced thrombocytopenia was studied in a 2000 bed teaching hospital with 21,000 admissions annually. Approximately 25% (5250 patients) received some form of heparin therapy (lV,SC, catheter flushes). In l6 months 21 patients(&lt;0.4%) developed well-documented thrombocytopenia while receiving therapeutic bovine lung heparin(IV). In 12 cases thrombocytopenia appeared to be directly related to heparin (Group 1). In 9 cases additional disease processes were also present (Group 2). While on heparin 5 patients in Group 1 (42%) developed new thrombotic episodes including pulmonary embolus,
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Takahashi, Hoyu, Wataru Tatewaki, Reizo Nagayama, Masaharu Hanano, Shin-ichiro Takizawa, and Akira Shibata. "HEAT-TREATED FACTOR VIII CONCENTRATES IN VON WILLEBRAND'S DISEASE AND RELATED DISORDERS: STUDIES IN PLATELET-TYPE VON WILLEBRAND'S DISEASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644118.

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Cryoprecipitate has proved to correct the hemostatic defects in von Willebrand1s disease (vWd). However, recent studies have revealed that transmission of the AIDS retrovirus (HIV) occurs through exposure to blood products including cryoprecipitate. Treatment with heat-treated factor VIII concentrates may have certain advantages over treatment with non-heated products, if these preparations are efficacious in vWd and related disorders. We investigated the multimeric compositoin of von Willebrand factor (vWf), contents of vWf antigen (vWf:Ag) and ristocetin cofactor activity (RCof) in the heat-
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FACON, T., J. GOUPEMAND, C. CARON, M. ZANDECKI, M. H. ESTIENNE, and A. COSSON. "GRAY PLATELET SYNDROME AND IDIOPATHIC PULMONARY FIBROSIS OCCURRING IN THE SAME PATIENT : A FORTUITOUS ASSOCIATION?" In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644559.

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A 46 yr old Caucasian woman has been diagnosed as having a congenital deficiency of platelet a-granules (gray platelet syndrome - GPS) associated with an extensive idiopathic pulmonary fibrosis (IPF). The patient had a life long history of bleeding tendency including dental bleedings in childhood, intraperitoneal bleeding, metrorrhagias which led to hysterectomy, and post-operative hemorrhages. When aged 16, splenectomy was performed because of a mild thrombocytopenia but did not result in a subsequent improvement of the platelet count. The spleen was enlarged and showed an excess of fibrous t
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Hattori, A., R. Nagayama, I. Fuse, T. Takeshige, S. Takizawa, and A. Shibata. "FURTHER CHARACTERIZATION OF PLATELET RELEASE MECHANISM DEFECT WITH DEFECTIVE A23187 AGGREGATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644878.

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In order to clarify the basic abnormality of patients with release mechanism abnormality with defective response to A23187 (A23) (Hattori et al. Acta Haematol. Jap. 44:969, 1981), the proband (female) showing a life long mild hemorrhagic tendency was further examined. Her platelet (pit) count, morphology, storage pool was normal. Bleeding time (Duke) was more than 15 min.PRP-aggregation (Ag) was normal when induced by PMA, whereas decreased (only primary Ag) by ADP, adrenalin, arachidonate (AA) (−2mM), Tx analog STA2 (−4μM), PAF (−10μM). Ag was defective in response to A23 (−40μM), Ag using wa
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Rocha, E., R. Llorens, J. A. Paramo, R. Arcas, B. Cuesta, and A. Martin Trenor. "DOES DESMOPRESSIN ACETATE REDUCE BLOOD LOSS AFTER CARDIOPULMONARY BYPASS SURGERY?" In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644710.

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It has been suggested that desmopressin acetate (DDAVP) administration reduces blood loss after cardiac surgery. We have investigated the effect of DDAVP administration in a doubleblind, randomized, prospective trial including 60 patients undergoing cardiopulmonary bypass surgery. Thirty patients received 0.3 ug/kg DDAVP and 30 patients a placebo. The infusion was administered in a 50 ml saline solution over 15 min when cardiopulmonary bypass had been concluded. Blood samples were taken before surgery, immediately before and 90 min after DDAVP or placebo administration, and 24 hours postoperat
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Reports on the topic "Including platelet count"

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Sowjanya, Dr Kaniti, Dr Bongu Srinivas, and Dr Metta Lakshmana Rao. A STUDY ON FIBROSCAN COMPARED TO AST TO PLATELET RATIO INDEX(APRI) FOR ASSESSMENT OF LIVER FIBROSIS WITH NONALCOHOLIC FATTY LIVER DISEASE(NAFLD). World Wide Journals, 2023. http://dx.doi.org/10.36106/ijar/1606016.

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Background : Nonalcoholic fatty liver disease (NAFLD) is increasingly recognized as a cause of chronic liver disease, and often results in the devastating outcomes of decompensated liver cirrhosis and hepatocellular carcinoma and is an important feature of metabolic syndromes and insulin resistance. The assessment of liver brosis is essential for predicting the prognosis and outcome of all forms of chronic liver disease. A liver biopsy is the gold standard for the assessment of liver brosis, but it has its limitations, which include life-threatening complications. Alternative methods of non-
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