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1

Centre for Independent Studies (N.S.W.), ed. The case against tax increases in Australia: The growing burden. The Centre for Independent Studies, 2016.

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2

Ratner, Svetlana, Liliya Nazarova, Kasiya Kirdasinova, and Anna Karapetyan. Circular model of economic growth: experience, opportunities and barriers. INFRA-M Academic Publishing LLC., 2022. http://dx.doi.org/10.12737/1893194.

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The concept of a circular (or circular/closed cycle) economy is quite new for the Russian scientific literature on economics and management. Having originated initially in countries experiencing serious resource constraints and (or) acute environmental problems, a few months ago it seemed to be a curious idea for Russia, allowing in the long term to achieve simultaneous preservation and even an increase in economic growth rates without the concomitant increase in the expenditure of natural resources and the inevitably associated increase in the burden on the environment. However, the dramatica
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3

Swendiman, Robert. Spending cuts, increased uncompensated care burden threaten rural hospitals in North Carolina: A case study. John F. Kennedy School of Government, 2014.

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4

Bush), United States President (1989-1993 :. Proposed legislation: "Credit Availability and Regulatory Relief Act of 1992" : message from the President of the United States transmitting a draft of proposed legislation to increase the amount of credit available to fuel local, regional, and national economic growth by reducing the regulatory burden imposed upon depository institutions, and for other purposes. U.S. G.P.O., 1992.

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5

Office, General Accounting. Paperwork reduction: Reported burden hour increases reflect new estimates, not actual changes : report to the ranking minority member, Committee on Government Operations, House of Representatives. The Office, 1993.

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6

Licinio, Julio, Andreas L. Birkenfeld, and Stefan R. Bornstein. Global burden of diabetes and depression. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198789284.003.0001.

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Diabetes and depression are two of the major global health concerns in the twenty-first century. One way of measuring the global impact of these illnesses are the disability-adjusted life-years or DALYs. The calculation takes into account the average life expectancy of a specific country, the years lost by premature death, and the years lived with disability/disease. Furthermore, ongoing research has shown that interactions exist between depression and diabetes. Diabetes and other chronic diseases can lead to depression, while depression can increase the risk for developing diabetes or worsen
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7

Yabroff, K. Robin, Gery P. Guy, Matthew P. Banegas, and Donatus U. Ekwueme. The Economic Burden of Cancer in the United States. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0010.

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With an aging and growing population and improved early detection and survival following diagnosis in the United States, the number of cancer survivors and prevalence of survivorship are expected to increase. Based on population trends, national expenditures for cancer care are projected to increase from $124.6 billion in 2010 to $157.8 billion in 2020. This chapter describes the economic burden of cancer, including direct costs, resulting from the use of resources for medical care for cancer; indirect costs, resulting from the loss of economic resources and opportunities associated with morbi
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8

Prisoners and Paupers : A Study of the Abnormal Increase of Criminals and the Public Burden of Pauperism in the United States: The Causes and Remedies. Creative Media Partners, LLC, 2022.

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9

Prisoners and Paupers : A Study of the Abnormal Increase of Criminals and the Public Burden of Pauperism in the United States: The Causes and Remedies. Creative Media Partners, LLC, 2022.

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10

Adhikari, Neill KJ. Critical Illness and Long-Term Outcomes Worldwide. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0002.

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Interest in the global burden of critical illness and its sequelae are growing, but comprehensive data to describe the burden of acute and post-acute illness and the resources available to provide care are lacking. Challenges to obtaining population-based global estimates of critical illness include the syndrome-based definitions of critical illness, incorrect equating of ‘critical illness’ with ‘admission to an intensive care unit’, lack of reliable case ascertainment in administrative data, and short prodrome and high mortality of critical illness, limiting the number of prevalent cases. Est
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11

Runhaar, Jos, and Sita M. A. Bierma-Zeinstra. Lifestyle. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0012.

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Modern lifestyles put a great burden on the human musculoskeletal system. Since 1980, the worldwide prevalence of obesity has tripled in many European countries. Obesity is known to affect both weight-bearing and non-weight-bearing joints due to a combination of mechanical overload and systemic inflammation. On the other hand, both to combat the obesity pandemic and to increase or maintain the quality of life, physical activity and sports are encouraged next to a healthy diet. Although both have a positive influence on cardiovascular risk factors, physical activity and especially sporting acti
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12

Tate, Robert Joseph. Prospects for increased U.S.-Japan defense burden-sharing. 1985.

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13

Thomas, Alcock. Observations on the Defects of the Poor Laws, and on the Causes and Consequences of the Great Increase and Burden of the Poor. with a Proposal for ... These Grievances. ... by Thomas Alcock, A.M. Gale Ecco, Print Editions, 2018.

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14

Donal, Erwan, and Elena Galli. Heart failure: left ventricular systolic dysfunction. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0025.

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Heart failure (HF) is a growing problem worldwide and poses an especially large public health burden. It represents a new epidemic of cardiovascular disease, affecting nearly 5.8 million people in the United States, and over 23 million worldwide. Nevertheless, in Europe, fears of an impending HF ‘epidemic’ could not be confirmed in this analysis of trends in prevalence for the period 1990-2007 in patients hospitalized with HF in Sweden. An overall slight decrease in age-adjusted prevalence was observed from 2002. The prevalence in patients under 65 years increased markedly. In absolute numbers
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15

Lin, Jaime. Talentos e Aptidões: Um olhar sobre o Autismo. Brazil Publishing, 2021. http://dx.doi.org/10.31012/978-65-5861-554-5.

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Autism is a medical term that encompasses a broad spectrum of neurodevelopmental disorders characterized by impaired reciprocal socialization and communication, often accompanied by restricted or repetitive patterns of behavior and interests. Due to the enlargement in the clinical diagnostic boundaries and the increased awareness of autism spectrum disorder (ASD), the world has seen a dramatic increase in its prevalence during the last two decades. ASD is currently considered one of the most common neurodevelopmental disorders worldwide. Frequently reported in terms of comorbidities, disabilit
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16

Thomas, Alcock. Observations on the Defects of the Poor Laws, and on the Causes and Consequences of the Great Increase and Burden of the Poor. with a Proposal for Redressing These Grievances... . by Thomas Alcock, A. M. HardPress, 2020.

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17

Kang, Duk-Hee, and Mehmet Kanbay. Urate nephropathy. Edited by Adrian Covic. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0092.

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Gout is a disorder of purine metabolism, characterized by hyperuricaemia and urate crystal deposition within and around the joints. The recognition of increased comorbidity burden in patients with gout rendered it as a systemic disorder rather than simply a musculoskeletal condition. Gout nephropathy (also known as chronic uric acid nephropathy or urate nephropathy) is a form of chronic tubulointerstitial nephritis, induced by deposition of monosodium urate crystals in the distal collecting ducts and the medullary interstitium, associated with a secondary inflammatory reaction. Other renal his
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18

Jemal, Ahmedin, D. Maxwell Parkin, and Freddie Bray. Patterns of Cancer Incidence, Mortality, and Survival. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0008.

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The global burden of cancer is expected to increase from 14.1 million newly diagnosed cases and 8.2 million cancer deaths in 2012 to 22 million cases and 13 million deaths in 2030. This increase, based on projected population aging and growth, will disproportionately affect low- and middle-income countries (LMICs), where large numbers of young adults are now surviving to older ages where cancer becomes common. The incidence of cancers traditionally associated with Western behavioral, environmental, and cultural factors (breast, colorectum, lung, and prostate) are increasing in LMICs, whereas c
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19

Townsend, William M., and Emma C. Morris. ICU selection and outcome of patients with haematological malignancy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0374.

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Patients with haematological malignancies require admission to the intensive care unit (ICU) due to the underlying disease, as a consequence of treatment with chemotherapy or after haematopoietic stem cell transplantation. With an increasing numbers of patients being diagnosed with these diseases and longer survival as treatments improve, the burden on ICU is anticipated to increase. There is compelling evidence that patients should not be denied admission to ICU based on the presence of a haematological malignancy. In this chapter the disease- and treatment-related reasons for ICU admission,
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HEARTS in the Americas Regulatory Pathway to the Exclusive Use of Validated Blood Pressure Measuring Devices. Pan American Health Organization, 2021. http://dx.doi.org/10.37774/9789275124864.

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Cardiovascular disease (CVD) is the leading cause of disease burden globally. According to the 2017 Global Burden of Disease estimates, there were 14 million new cases of CVD, 80 million people living with this condition, and nearly 1 million deaths attributed to CVD in the Americas. Hypertension is the major risk factor for CVD, causing half of the cases, and is highly prevalent, affecting one in four adults, including 40% of those over age 25 years.To appropriately detect hypertension, accurate measurement of blood pressure is critical, and inaccurate measurement of BP has important conseque
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21

Torres, Albina R., Leonardo F. Fontenelle, Roseli G. Shavitt, Marcelo Q. Hoexter, Christopher Pittenger, and Euripedes C. Miguel. Epidemiology, Comorbidity, and Burden of OCD. Edited by Christopher Pittenger. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228163.003.0004.

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This chapter addresses the interrelated topics of OCD epidemiology, comorbidity, and disease burden. Obsessive-compulsive disorder (OCD) is a frequent condition, especially if subthreshold manifestations are considered. Epidemiological surveys describe current and lifetime prevalence rates of full-blown OCD around 1% and 2.5%, respectively. Subthreshold symptoms occur in up to a third of the general population. Comorbidity is the rule in OCD, which increases the complexity, severity, distress, chronicity, and negative impact of the disorder. Comorbidity may influence the search for, adherence
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22

Mukherjee, Joia S. Human Resources for Health. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190662455.003.0007.

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Impoverished countries face what has been termed a human resource crisis. Decades of under-resourced training programs, low public sector wages, and poor working conditions have led to shortages of health workers and the underperformance of staff where the burden of disease is the highest. In this chapter, the causes of the human resource crisis are explained and the gaps in training and retention of personnel are described. The chapter outlines new programs, such as the Medical Education Partnership Initiative (MEPI), Nursing Education Partnership Initiative (NEPI), and the Rwanda government’
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23

Andrews, Peter J. D., and Jonathan K. J. Rhodes. Assessment of traumatic brain injury. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0342.

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Traumatic brain injury (TBI) accounts for the majority of traumatic deaths and most disability due to trauma in people aged less than 40 years old. Current trends suggest this burden of disease will increase dramatically over the next 20 years. Successful management of patients after traumatic brain injury requires recognition of patients at risk of deterioration, appropriate investigation, including imaging, and prevention of systemic and intracranial secondary injury processes. Unlike trauma affecting other body systems, outcome from TBI has not improved in the last 10–15 years. Assessment o
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24

Rao, Seema. Integrated Approaches to Treating Lung Diseases in the Geriatric Population. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190466268.003.0018.

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Structural and functional changes in the aging lung and body predispose the older patient to pulmonary diseases such as asthma, chronic obstructive pulmonary disease, and chronic dyspnea. Pulmonary diseases of the aging population have a negative impact on morbidity and mortality and quality of life and increase the burden on health care costs. Pharmacological treatment remains the standard of care, but polypharmacy in the older patients can be an issue and has been associated with negative consequences. Integrative or nonpharmacological approaches can be used in conjunction with conventional
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25

Banerjee, Amitava, and Kaleab Asrress. Prevention of cardiovascular disease. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0343.

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The global scale of the cardiovascular disease epidemic is unquestionable, with cardiovascular disease causing a greater burden of mortality and morbidity than any other disease, regardless of country or population. With demographic change and ageing populations, the prevalence of cardiovascular disease and its risk factors is set to increase. The commonest cardiovascular diseases are atherosclerotic, affecting all arterial territories. The ‘burden of disease’ approach has highlighted the fact that cardiovascular disease and non-communicable diseases are not simply diseases of affluence but af
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26

The Case for Investment in Prevention and Control of Noncommunicable Diseases in Jamaica: Evaluating the return on investment of selected tobacco, alcohol, diabetes, and cardiovascular disease interventions. Organización Panamericana de la Salud, 2018. http://dx.doi.org/10.37774/9789275120545.

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Noncommunicable diseases (NCDs) are a major driver of morbidity and mortality in Jamaica. Beyond the toll on health, NCDs also impose a significant burden on the national economy since individuals with NCDs are more likely to exit the labor force, miss days of work, and/or work at reduced capacity. In addition, high expenditures to treat NCDs impose a direct economic burden to the health system, the society and to the nation of Jamaica, which can lead to reduced investments in areas like education and physical capital, which increase gross domestic product (GDP) in the long run. Unless urgentl
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27

Rello, Jordi, and Bárbara Borgatta. Pathophysiology of pneumonia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0115.

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Airway colonization, ventilator-associated tracheobronchitis (VAT), and hospital-acquired (HAP) and ventilator-associated pneumonia (VAP) are three manifestations having the presence of micro-organisms in airways in common. Newer definitions have to consider worsening of oxygenation, in addition to purulent respiratory secretions, chest-X rays opacities, and biomarkers of inflammation. Bacteria are the main causes of HAP/VAP. During hospitalization there’s a shift of airway’s colonizing flora from core organisms to enteric and non-fermentative ones. Macro- and micro-aspiration is the most impo
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28

Tsai, Po-Heng. Cognitive Enhancers for Alzheimer’s Disease. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190214401.003.0003.

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Alzheimer’s disease (AD) is the most common cause of dementia. In the United States, an estimated 5.3 million people had AD dementia in 2015, including 200,000 individuals younger than age 65 years. The number of people who are affected by AD is projected to reach 16 million in 2050. There is a tremendous cost associated with caring for people with AD. In 2015, the direct costs to US society of caring for those with AD totaled an estimated $226 billion, and if no effective disease-modifying treatments become available, this could increase to $1.1 trillion in 2050. In addition to medical costs,
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Carvalho, André F., Gilberto S. Alves, Cristiano A. Köhler, and Roger S. McIntyre. Cognitive Enhancement in Major Depressive Disorder. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190214401.003.0010.

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Major depressive disorder (MDD) is a chronic and disabling illness often associated with elevated rates of non-recovery and substantial psychosocial burden. Cognitive impairment is a common residual manifestations of MDD. Overactivation of the hypothalamic–pituitary–adrenal axis, along with immune–inflammatory imbalances, a decrease in neurotrophin signaling, and an increase in oxidative and nitrosative stress, leads to neuroprogression and cognitive deterioration in MDD. “Cognitive remission” has been proposed as a novel treatment target for MDD. Cognitive remediation therapy has provided enc
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Marini, John J., and Paolo Formenti. Pathophysiology and prevention of sputum retention. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0119.

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Retention of airway mucus is one of the major problem that confronts post-operative and critically-ill patients, as well as the caregivers that address it. Retained secretions increase the work of breathing and promote hypoxaemia, atelectasis, and pneumonia. The airway-intubated patient is at particular risk of retaining mucus, as the presence of the tube interrupts normal flow of airway secretions toward the larynx by the mucociliary escalator and coughing effectiveness is degraded by a glottis that is stented open and cannot close effectively. Clearance of mucus is aided by using sufficient
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Breitbart, William S., ed. Meaning-Centered Psychotherapy in the Cancer Setting. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199837229.001.0001.

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There is an evolution taking place regarding the nature and scope of the clinical goals of psychotherapeutic or counseling interventions in the palliative care setting. Meaning-Centered Psychotherapy in the Cancer Setting provides a theoretical context for meaning-centered psychotherapy (MCP), a nonpharmacologic intervention that has been shown to enhance meaning and spiritual well-being, increase hope, improve quality of life, and significantly decrease depression, anxiety, desire for hastened death, and symptom burden distress in the cancer setting. Based on the work of Viktor Frankl and his
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32

McDougall, Robert. Management of Burn Patients for Grafting and Excision. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0026.

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Anesthesia management for excision and grafting of burns in a child can be extremely challenging. Early excision of burned tissue significantly decreases morbidity and mortality but often involves procedures that lead to significant blood loss. Burn patients also have a markedly increased metabolic rate secondary to the inflammatory response to the burn. Burn patients may be difficult to monitor, are at risk of hypothermia, and present complex pain-management problems.
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33

Lameire, Norbert, Wim Van Biesen, and Raymond Vanholder. Overall outcomes of acute kidney injury. Edited by Norbert Lameire. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0237_update_001.

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This chapter describes the overall short- and long-term, mainly non-renal outcomes of patients who suffer from acute kidney injury (AKI). Despite increasing age and greater burden of co-morbidity at the occurrence of AKI, patient mortality shows an overall decline over time. However, relatively ‘mild’ forms of AKI (i.e. defined as an absolute increase in serum creatinine of at least 0.3 mg/dL (26.4 µmol/L)) are associated with statistically significant decreased patient survival. The absolute mortality rates of AKI vary according to the different patient groups studied (intensive care unit, ho
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34

McCrea, Michael A., and Lindsay D. Nelson. Effects of Multiple Concussions. Edited by Ruben Echemendia and Grant L. Iverson. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199896585.013.10.

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There is growing concern that suffering multiple sport-related concussions may increase an athlete’s risk of cumulative neurocognitive and neurobehavioral impairment. Many concerns have not been well-validated, however, owing to limited samples of repeatedly concussed players. In this article, we review the theoretical risks and current evidence regarding the extent to which repeat concussions impact players’ experience of and recovery following successive injuries. Concussion effects are considered at multiple levels (e.g., self-reported physical and psychiatric symptoms, neuropsychological p
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35

Schneider, Antoine G., Neil J. Glassford, and Rinaldo Bellomo. Choice of Renal Replacement Therapy and Renal Recovery. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0038.

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Acute kidney injury (AKI) is a major complication of critical illness, associated with increased mortality and morbidity. Among survivors of AKI, a subset will develop the need for chronic dialysis. Chronic dialysis imposes a major physical, emotional, economic, and social burden on ICU survivors and their caregivers. Evidence suggests that the type of renal replacement therapy used in the acute setting may affect renal recovery differently. For example, intermittent haemodialysis (IHD) increases the risk of hypotension and acute volume and solute fluctuations, and such physiological events ha
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36

Vermeulen, Karla. Generation Disaster. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780190061630.001.0001.

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Generation Disaster: Coming of Age Post-9/11 is an in-depth examination of the multiple stressors that shaped the developmental environment for today’s emerging adults in their youth and as they now take on adult responsibilities in an unprecedentedly complex world. Those stressors include all of the societal changes that occurred in the United States after the attacks of September 11, 2001, as well as other threats like the increase in school shootings and other human-caused disasters, worsening natural disasters and concerns about the future due to climate change, and the global pandemic. Th
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Reinecke, Holger. Epidemiology and global burden of peripheral arterial disease and aortic aneurysms. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0068.

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Peripheral artery disease (PAD) and aortic aneurysms are common diseases which show an increasing prevalence and incidence. From community-based trials assessing ankle–brachial indices, 2–4% of the general population have been shown to be affected by PAD, which increases up to 15% in those above 70 years of age. About 30–40% of the in-hospital cases with PAD have critical limb ischaemia and suffer from a 1-year mortality of 20–40%. Abdominal aortic aneurysms (AAAs) also show a relatively high prevalence of about 1–2% in the general population as found by large-scale, systematic duplex screenin
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38

Deen, Jason F., and Karen K. Stout. Causes and diagnosis of valvular problems. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0158.

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While valvular heart disease encountered in developing countries is primarily rheumatic in aetiology, in industrialized countries it is largely comprised of degenerative valvular disease. Although less prevalent than ischaemic heart disease, its prevalence increases with older age and increased life expectancy, and therefore represents significant disease burden in aging populations. Transthoracic echocardiography remains the imaging modality of choice for timely delineation of the anatomy and severity of the lesion,although, once identified, may not correlate with symptoms due to clinical lat
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Zhang, Luxia, and Haiyan Wang. Chronic kidney disease in developing countries. Edited by David J. Goldsmith. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0096_update_001.

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The spread of non-communicable diseases (NCDs) is a barrier to the development of goals including reduction of poverty, health equity, economic stability, and human security. NCDs accounted for 61% of the estimated 58 million deaths and 46% of the global burden of diseases worldwide in 2005. Among NCDs, chronic kidney disease (CKD) is of particular significance. It is recognized that the burden of CKD is not only limited to its impact on demands for renal replacement therapy but has equally major impacts on the health of the overall population. For example, it is now well established that amon
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40

Thomas, Gregory S., L. Samuel Wann, and Myrvin H. Ellestad, eds. Ellestad's Stress Testing. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190225483.001.0001.

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The 6th edition of the textbook Ellestad’s Stress Testing: Principles and Practice was written for the new and veteran clinician alike performing stress testing. Thoroughly updated, referenced and interspersed with case examples, the book reviews how to get the most out exercise testing, without and with ancillary imaging. In addition to evaluation of ST segment depression, other powerful tools to detect ischemia and forecast the future are reviewed to increase the diagnostic accuracy and prognostic ability of exercise testing. The recognition and significance of exercise induced arrhythmias a
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41

Jeynes, William H. School Choice. ABC-CLIO, LLC, 2014. http://dx.doi.org/10.5040/9798216011149.

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Are public charter schools more effective than traditional public schools? This book provides quantitative evidence to answer this question and considers a better way to undertake a policy of school choice. School Choice: A Balanced Approach is the most comprehensive examination of traditional public schools, public charter schools, and faith-based schools that has ever been undertaken. By considering and comparing the overall data on these three types of educational systems, it provides insight on likely outcomes of school choice programs. The author's objective is not to advance any particul
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42

Carlucci, Annalisa, and Paolo Navalesi. Weaning failure in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0103.

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Weaning failure has been defined as failure to discontinue mechanical ventilation, as assessed by the spontaneous breathing trial, or need for re-intubation after extubation, so-called extubation failure. Both events represent major clinical and economic burdens, and are associated with high morbidity and mortality. The most important mechanism leading to discontinuation failure is an unfavourable balance between respiratory muscle capacity and the load they must face. Beyond specific diseases leading to loss of muscle force-generating capacity, other factors may impair respiratory muscle func
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43

Lally, John, and James H. MacCabe. Epidemiology, impact, and predictors of treatment-resistant schizophrenia. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198828761.003.0004.

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Treatment-resistant schizophrenia (TRS) is a disabling psychotic disorder that affects approximately 30% of those diagnosed with schizophrenia. In a significant proportion (about 70%) of patients with TRS, their illness is treatment-resistant from onset (early or primary treatment resistance), whilst, in the remainder, treatment resistance develops during the course of illness (late or secondary treatment resistance). TRS is associated with reduced quality of life and increased social and economic burden. Multiple sociodemographic, clinical, and biological risk factors have been assessed in re
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44

Benedetto, Chiara, Ilaria Castagnoli Gabellari, and Gianni Allais. Migraine and pregnancy-related hypertension. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198749547.003.0005.

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Migraine is one of the most common, disabling neurological disorders in women of reproductive age. It is a disabling condition that can lead to a compromised health-related quality of life. Often `migraineurs' are unable to carry out everyday tasks due to a reduction in functioning and productivity. This burden impacts not only at work, but also on social and family life. Migraine affects not only the physical but also mental and social health. Chapter 5 discusses the available evidence of a correlation between migraine and pre-eclampsia. Pre-eclampsia complicates 3-5% of all pregnancies and r
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45

Webster, Lynn. The Painful Truth. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190659721.001.0001.

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The Painful Truth describes the personal and social implications of living with chronic pain and paints a picture of how society can do a better job of helping people who are in pain. In Part 1, the author-a former president of the American Academy of Pain Medicine-tells in-depth stories about some of his patients, using each story to focus on a key issue that frequently surfaces in the lives of people who have pain. The value of a positive attitude, the way that pain combines with other things going on in a person’s life, the reality of prejudice, the risk of becoming addicted to opioids, the
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46

McDermid, Robert C., and Sean M. Bagshaw. Physiological Reserve and Frailty in Critical Illness. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0028.

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Physicians have long sought to define a ‘physiologic age’ distinct from chronologic age which might account for some of the variance in response to critical illness and injury. This has led to the concept of ‘physiologic reserve’ which might represent a major driver of outcome in patients requiring intensive care. The human body is a complex system that adapts to a multitude of external stressors; however, senescence or illness can reduce inherent adaptive mechanisms, reducing complexity and reducing the threshold for decompensation (i.e. acute illness or injury). This theoretical critical thr
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47

Higher education: Institutions' reported data collection burden is higher than estimated but can be reduced through increased coordination : report to congressional committees. U.S. Govt. Accountability Office, 2010.

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48

Teoh, Eugene, and Michael J. Weston. Computed tomography. Edited by Christopher G. Winearls. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0014.

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Computed tomography (CT) has increased in use exponentially for the assessment of patients with renal tract pathology. This has been promoted by the availability of multidetector thin-slice CT so that intravenous urography has been superseded by CT urography. The latter may be considered as a ‘one-stop’ imaging investigation for haematuria, with increased detection of both urinary tract cancers and urolithiasis. Multiplanar reformats are made possible with the use of thin slices, allowing clear delineation of other pathologies such as urinary tract injury. In the transplant recipient, protocol
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49

Thomas, Bernadette A., and Christopher R. Blagg. Patient selection when resources are limited. Edited by David J. Goldsmith. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0147_update_001.

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More than 50 years ago, outpatient care for patients with end-stage renal disease (ESRD) became possible through the invention of the Scribner shunt. Since that time, renal replacement therapy (RRT) has expanded to include haemodialysis, peritoneal dialysis, and renal transplantation. There has been tremendous global growth in the number of patients with access to RRT for ESRD, but many societies face difficult triage decisions for these costly modalities similar to those faced by the pioneers of outpatient dialysis in the early 1960s. Developed and developing societies will face the complex c
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50

Paperwork reduction: Reported burden hour increases reflect new estimates, not actual changes : report to the ranking minority member, Committee on Government Operations, House of Representatives. The Office, 1993.

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