Relevant bibliographies by topics / Increased sensitivity

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Increased sensitivity'

Author: Grafiati
Published: 4 June 2021
Last updated: 18 February 2022

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Journal articles on the topic "Increased sensitivity"

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Bernard, S., D. J. Clarke, M. X. Chen, I. B. Holland, and A. Jacq. "Increased sensitivity of." MGG - Molecular and General Genetics 259, no. 6 (1998): 645. http://dx.doi.org/10.1007/s004380050859.

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Beauducel, Claude, and Thierry Gautier. "Increased sensitivity piezoelectric hydrophones." Journal of the Acoustical Society of America 86, no. 4 (October 1989): 1637. http://dx.doi.org/10.1121/1.398589.

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Scopsi, L., and L. I. Larsson. "Increased sensitivity in immunocytochemistry." Histochemistry 82, no. 4 (1985): 321–29. http://dx.doi.org/10.1007/bf00494060.

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Knight, Paul R., Carlos Kurek, Bruce A. Davidson, Nader D. Nader, Alka Patel, June Sokolowski, R. H. Notter, and Bruce A. Holm. "Acid aspiration increases sensitivity to increased ambient oxygen concentrations." American Journal of Physiology-Lung Cellular and Molecular Physiology 278, no. 6 (June 1, 2000): L1240—L1247. http://dx.doi.org/10.1152/ajplung.2000.278.6.l1240.

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Previously we have demonstrated that prolonged exposure to 100% ambient oxygen leads to a marked loss in functional lung volume and lung compliance, hypoxemia, and surfactant system abnormalities similar to acute respiratory distress syndrome (ARDS). However, 50% oxygen administration is believed to be safe in most clinical settings. In the present study, we have evaluated the effects of a 24-h exposure to 50% oxygen in rabbits immediately following experimental gastric acid aspiration. Mild hypoxemia, but no changes in mortality, lung volume, lung compliance, surfactant metabolism, or edema formation occurred after 24 h of normoxia postacid aspiration. Conversely, a relatively short (24-h) exposure to 50% oxygen after acid aspiration results in increased pulmonary edema, physical signs of respiratory distress, and mortality, as well as decreased arterial oxygenation, lung volume, lung compliance, and type II alveolar cell surfactant synthesis. These results suggest that acid aspiration alters the “set point” for oxygen toxicity, possibly by “priming” cells through activation of inflammatory pathways. This pathogenic mechanism may contribute to the progression of aspiration pneumonia to ARDS.
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&NA;. "Increased sensitivity to insect stings?" Reactions Weekly &NA;, no. 301 (May 1990): 2. http://dx.doi.org/10.2165/00128415-199003010-00002.

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Hellyer, Paul. "Greater occlusal sensitivity = increased parafunction?" British Dental Journal 227, no. 7 (October 2019): 585. http://dx.doi.org/10.1038/s41415-019-0847-9.

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Frank, Lawrence R., Eric C. Wong, Thomas T. Liu, and Richard B. Buxton. "Increased diffusion sensitivity with hyperechos." Magnetic Resonance in Medicine 49, no. 6 (May 16, 2003): 1098–105. http://dx.doi.org/10.1002/mrm.10457.

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Gillam, Ronald B., LaVae M. Hoffman, Jeffrey A. Marler, and M. Lorraine Wynn-Dancy. "Sensitivity to Increased Task Demands." Topics in Language Disorders 22, no. 3 (May 2002): 30–48. http://dx.doi.org/10.1097/00011363-200205000-00005.

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Scopsi, L., and L. I. Larsson. "Increased sensitivity in peroxidase immunocytochemistry." Histochemistry 84, no. 3 (1986): 221–30. http://dx.doi.org/10.1007/bf00495786.

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Wallis, Elisabeth, David H. Overstreet, and Ann D. Crocker. "Selective breeding for increased cholinergic function: Increased serotonergic sensitivity." Pharmacology Biochemistry and Behavior 31, no. 2 (October 1988): 345–50. http://dx.doi.org/10.1016/0091-3057(88)90356-5.

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Dissertations / Theses on the topic "Increased sensitivity"

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Jurgelucks, Benjamin [Verfasser]. "Increased sensitivity in parameter identification problems for piezoelectrics / Benjamin Jurgelucks." Paderborn : Universitätsbibliothek, 2019. http://d-nb.info/1183087462/34.

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Hikida, Takatoshi. "Increased sensitivity to cocaine by cholinergic cell ablation in nucleus accumbens." Kyoto University, 2002. http://hdl.handle.net/2433/149673.

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Frye, Jacob Nathaniel. "Increased arterial stiffness and reduced cardiovagal baroreflex sensitivity with anti cancer chemotherapy." Thesis, Kansas State University, 2017. http://hdl.handle.net/2097/36244.

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Master of Science
Department of Kinesiology
Carl Ade
Background – Chemotherapy-induced left ventricular cardiotoxicity is associated with many cancer treatments; however, what is less known is how these treatments affect vascular health and autonomic control of blood pressure. Arterial stiffness and cardiovagal baroreflex sensitivity (BRS) are indicators of cardiovascular health and may provide insight into the adverse effects of anti-cancer chemotherapy. Therefore, the primary aims of the present study were to evaluate carotid artery stiffness and arterial BRS in cancer patients currently being treated with adjuvant chemotherapy. Methods – We performed a cross-sectional, case-control study involving 9 cancer patients and 9 age- and sex-matched controls. Carotid artery stiffness was assess via 2D ultrasonography. Cardiovagal BRS was assessed from the spontaneous changes in beat-to-beat time series of R-R interval and systolic blood pressure via the cross correlation technique. Results – Our findings indicated a significant decrease in cardiovagal BRS in cancer patients compared to controls (4.7 ± 0.6 vs 9.2 ± 1.7 msec mmHg⁻¹ respectively, P = 0.02). Carotid artery β-Stiffness was significantly higher in the cancer patients compared to control participants (9.2 ± 1.2 vs 6.6 ± 0.74 U respectively, P = 0.05). Conclusions – These data suggest that anti-cancer chemotherapy elicits significant decreases in the autonomic control of blood pressure and arterial stiffness, leaving cancer survivors with an increased risk of future cardiovascular disease.
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Reyes, de Corcuera José Ignacio. "Increased sensitivity of enzyme-based amperometric glucose biosensors and their application as time-temperature integrators." Online access for everyone, 2004. http://www.dissertations.wsu.edu/Dissertations/Spring2004/J%5FDe-Corcuera%5F050404.pdf.

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Dudgeon, Lori Snyder. "Elevated Temperatures Perturb Lipopolysaccharide Leading to Increased Serum Complement Sensitivity in Most Gram-Negative Bacteria." W&M ScholarWorks, 1995. https://scholarworks.wm.edu/etd/1539625965.

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Mailman, Matthew David. "Molecular analysis of patients with recessive 5q-spinal muscular atrophy : increased diagnostic and prognostic sensitivity /." The Ohio State University, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=osu1486572165277248.

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Marcantonio, Daniela. "The catecholamine extraneuronal uptake, transporter is associated with the increased sensitivity of gliomas to sarcosinamide chloroethylnitrosourea /." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=20273.

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SarCNU, a novel chloroethylnitrosourea analogue, is transported by the extraneuronal uptake2 transporter (uptake2). SK-MG-1 human glioma cells are sensitive to SarCNU cytotoxicity and express uptake 2 whereas SKI-1 glioma cells have no detectable transporter, and are relatively resistant. To clone uptake2, we detected differences in RNA expression utilizing differential display. With differential display, we detected a novel sequence expressed in SK-MG-1 cells but not in SKI-1 cells, having 62% homology to an expressed sequence tag clone from human brain, and could be a partial sequence of uptake2. In the treatment of SF-295 glioma xenografts in athymic mice, SarCNU had superior activity than 1,3-bis-(2-chloroethyl)-1-nitrosourea. This suggested that SF-295 cells express uptake2. We determined if expression of uptake2 in the established SF-295 cell line correlated with the enhanced activity of SarCNU in vivo. Transport of [3H]SarCNU was not decreased by inhibitors of uptake2 in the SF-295 cell line and its steady state accumulation was similar to that of SKI-1. The increased stability of SarCNU versus BCNU may account for its enhanced activity in vivo or the expression of uptake2 in vivo may differ from its expression in vitro.
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Carrigan, Shawn D. "Development of hydrogel platforms for increased QCM-D biointerface sensitivity in real-time immunoassay of sepsis-related biomarkers." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86068.

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This doctoral thesis describes the development of novel rapid deposition hydrogel platforms that serve as biointerfaces for real-time immunoassay using quartz crystal microgravimetry (QCM). Biointerface development was undertaken with the goal of developing a simple system relying on affordable technology to achieve real-time immunoassay performance equivalent to more complex and involved protocols.
The primary advantage of the hydrogel biointerfaces developed herein lies in their rapid preparation using affordable, non-toxic reagents. Compositions developed over three sequential development cycles rely on chemically cross-linking carboxymethylcellulose, which serves to covalently immobilise recognition elements through amine coupling, to polyethyleneimine. The various compositions require 10 minutes or less to deposit, a substantial improvement over competing self-assembled monolayer protocols requiring incubations ranging from hours to days using highly toxic reagents. Additional benefit lies in the immunoassay functionality of the biointerface, as these compositions excel in the traditional performance criteria of surface regeneration, minimisation of non-specific protein binding, and assay detection limit.
The peak detection limit achieved using a sandwich assay for a 17 kDa cytokine was 25 ng/mL in buffer and 500 ng/mL in a 1:3 serum dilution, with generic immunoassay capability for other cytokines demonstrated. Reusability of the developed biointerfaces is equally strong, with up to twenty regeneration cycles demonstrated without diminished sensitivity. Finally, mass-based estimates of non-specific serum adsorption indicate that the composition developed during the final design iteration equals the performance of the best protein-resistant biointerfaces currently available in the literature.
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Ramos-Gómez, Minerva. "Sensitivity to carcinogenesis is increased and chemopreventive efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice." Available to US Hopkins community, 2002. http://wwwlib.umi.com/dissertations/dlnow/3080748.

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Parise, Cláudia Klose. "Sensitivity and memory of the current mean climate to increased Antarctic sea ice: The role of sea ice dynamics." Instituto Nacional de Pesquisas Espaciais (INPE), 2014. http://urlib.net/sid.inpe.br/plutao/2014/11.19.18.13.

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Esta tese estuda a sensibilidade e memória do clima global ao aumento do gelo marinho Antártico, levando em consideração o tempo de persistência dos máximos de gelo (concentração e espessura) sob condições climáticas atuais. A sensibilidade das \emph{storm tracks} no Hemisfério Sul e do clima da América do Sul ao aumento do gelo marinho também são analisadas, bem como o mecanismo envolvido na restauração do equilíbrio climático. Dois grupos de experimentos foram realizados. No primeiro o gelo marinho é simulado por um modelo de única camada que desconsidera a reologia do gelo, impedindo que o gelo mova quando espesso. No segundo, o gelo marinho é simulado por um modelo multi-camadas que resolve explicitamente a dinâmica do gelo. Cada clima é perturbado com um extremo de condições positivas (\emph{Max}) e climatológicas (\emph{ctl}) de concentração e espessura de gelo marinho Antártico em um conjunto de 30-membros integrados por 10 anos cada. Alterações nas \emph{storm tracks} são analisadas através de um método automatizado de identificação e rastreio de ciclones extratropicais com base em vorticidade relativa. Os resultados mostram que um extremo de gelo marinho Antártico é capaz de persistir $\sim$4-anos sob condições climáticas atuais. Nos 4 anos seguintes o gelo marinho nos experimentos \emph{Max} é semelhante àquele dos experimentos \emph{ctl} e nos últimos 2-anos as diferenças (\emph{max- ctl}) de gelo marinho são negativas. A persistência dos máximos de gelo marinho varia setorialmente e em função do tipo de modelo de gelo. A presença de máximos de gelo marinho Antártico reduz a temperatura do ar dos baixos aos médios níveis da troposfera. O resfriamento das altas latitudes aumenta o transporte de calor para sul e a convergência em baixos níveis. A pressão média ao nível do mar é reduzida (aumentada) sobre as altas (médias) latitudes, padrão típico da fase positiva do Modo Anular Sul. O fluxo de calor sensível do oceano para a atmosfera é intenso nas margens do gelo marinho, onde a baroclinia da atmosfera também aumenta. Os ventos de oeste se intensificam ao sul de $50^{0}$S e se enfraquecem entre $45^{0}$S e $10^{0}$S. A corrente de jato polar se intensifica em direção aos pólos enquanto o jato subtropical se enfraquece em direção ao equador. Em resposta ao fortalecimento do jato polar, a densidade de trajetóricas dos ciclones, ciclogênese e ciclólise aumenta sobre as altas (médias) latitudes. Com o deslocamento das tempestades para sul, a atividade dos distúrbios transientes é reduzida sobre a América do Sul, bem como a formação de ciclones sobre as duas principais regiões ciclogenéticas (em $30^{0}$S e $45^{0}$S). O enfraquecimento do jato subtropical contribui para aumentar a estabilidade estática da atmosfera e reduzir a taxa de precipitação sobre a América do Sul. Os fortes ventos de oeste fortalecem a Corrente Circumpolar Antártica e, conseqüentemente, a deriva de Ekman para o norte. O derretimento do máximo de gelo marinho gera uma entrada da água fria e pouco salina na camada de mistura do Oceano Austral. A medida que essa água superficial flui para o norte há ressurgência da água mais quente e salina (observada abaixo da camada de mistura do oceano) na Divergência Antártica ($60^{0}$S). A memória climática ($\sim$8-anos) armazenada nas camadas superiores do oceano modula a intensidade e duração da resposta atmosférica ao máximo de gelo marinho.
This thesis explores the sensitivity and memory of the global climate to increased Antarctic sea ice, taking into account the persistence of sea ice maxima (in concentration and thickness) under current climate conditions. Moreover, the sensitivity of the Southern Hemisphere storm tracks and the South America climate to increasedAntartictic sea ice are also studied as well as the mechanisms involved in restoring the climate balance. In order to isolate the impacts of sea ice dynamics, two sets of sensitivity experiments are performed with the GFDL CM2.1 coupled climate model. In the first set the sea ice is simulated by a simple slab sea ice model which neglects the sea ice dynamics whereas in the second the sea ice is simulated by a sophisticated multi-layer model. The current climate is perturbed with maximum conditions of Antarctic sea ice (max) and compared to the respective control simulation (ctl). The four numerical experiments are integrated for 10 years each in a large 30-member ensemble. The changes to the Southern Hemisphere extratropical cyclones are analysed through an automated of cyclone identification and tracking based on relative vorticity. The impact of increased Antarctic sea ice on the South America climate is analysed through changes in the precipitation regime and the associated atmospheric systems. The results show that a maximum condition of Antarctic sea ice is able to persist $\sim$4-years under current climate conditions.In the following 4-years of model integration the sea ice in the max experiments is similar to that of the ctl experiments and in the last 2-years the (max-ctl) sea ice differences are negative. However, the persistence of Antarctic sea ice maxima varies sectorally and according to the sea ice model type. The Antarctic sea ice maxima reduce the air temperature from the low to mid-levels. This increases the poleward meridional temperature gradient, resulting in air ascending over the high-latitudes.The mean sea level pressure is reduced (increased) over the high (mid)-latitudes, a typical pattern of the Southern Annular Mode positive phase. The sensible heat flux from the ocean to the atmosphere is intensified at the sea ice edges increasing the atmospheric baroclinicity there. The westerly winds are intensified south of 50$^{°}$S and weakened from 45$^{°}$S to 10$^{°}$S. The polar jet stream intensifies poleward whereas the subtropical jet stream weakens toward the Equator. In response to the polar jet strengthening, the cyclone track density, cyclogenesis and cyclolysis have increased (decreased) over the high (mid)-latitudes. The eddy activity is reduced over South America as well as the cyclogenesis over the two main regions (at 30$^{°}$S and 45$^{°}$S ). The weaker subtropical jet contributes to enhanced atmospheric static stability and reduces the precipitation rate over South America. The stronger westerlies strengthen the Antarctic Circumpolar Current and, consequently, the Ekman drift northward. The melting of the sea maximum generates an imput of cold and fresh melt water into the ocean mixed-layer of the Southern Ocean (from the surface to 100 m ). As this surface water flows northward there is upwelling of the warmer and saltier water (observes below the ocean mixed-layer) on the Antarctic Divergence (60$^{°}$S). The climate memory stored in the upper ocean layers ($\sim$8-years) modulates the intensity and timing of the atmospheric response.
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Books on the topic "Increased sensitivity"

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Levine, Jerome I. Medications that increase sensitivity to light: A 1990 listing. [Rockville, Md.?]: U.S. Dept. of Health and Human Services, Public Health Service, Food and Drug Administration, Center for Devices and Radiological Health, 1991.

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Angus, Douglas E. Consumer sensitivity to increases in the price of magazine subscriptions. [Ottawa]: Coopers & Lybrand Consulting Group, 1986.

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Yobbi, D. K. Testing the sensitivity of pumpage to increases in surficial aquifer system heads in the Cypress Creek well-field area, West-Central Florida: An optimization technique. Tallahassee, Fla: U.S. Dept. of the Interior, U.S. Geological Survey, 2002.

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Monteleone, Erminio, and Mario Bertuccioli, eds. Secondo Convegno Nazionale della Società Italiana di Scienze Sensoriali. Florence: Firenze University Press, 2009. http://dx.doi.org/10.36253/978-88-8453-872-7.

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Over the last decade there has been a growing interest in sensory science in Italy. This has clearly resulted in an increase in the number of researchers engaged in this sector and the number of companies that exploit sensory evaluations for product innovation and enhancement and in quality control. In Italy, in the sphere of the valorisation of prestige foodstuffs there is an increasing sensitivity towards the adoption of strict methods for describing the sensory properties of the products and ascertaining compliance with defined sensory standards. The Società Italiana di Scienze Sensoriali has played a decisive role in activating and guiding this development. Pursuing this approach, in 2008 the Society organised the 2nd National Convention as an occasion for exchange among professionals working in the field of sensory science.
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Grimaldi, Stephanie J., and Emily R. Stern. Sensory Processing and Intolerance in OCD. Edited by Christopher Pittenger. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228163.003.0011.

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Patients with obsessive-compulsive disorder (OCD) often exhibit abnormal sensitivity to sensory stimuli and a reduced ability to screen out stimuli that most do not find bothersome. This chapter reviews evidence documenting increased sensitivity to external sensory stimuli (auditory, olfactory, tactile) and reduced sensory gating in patients with OCD. In some individuals such sensitivity can present as a primary symptom. Many patients with OCD also experience sensations that appear to be “internally generated,” including not-just-right experiences, incompleteness, and physical urges; this is the focus of the second half of the chapter. These sensations, termed “sensory phenomena,” cause significant distress and impairment in daily functioning and may require different treatments than fear-based obsessions. The chapter concludes with a brief discussion of directions for future research that may provide further insight into the nature of sensory symptoms as well as potential treatments.
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Carpenter, Gregory, and Meenal Patil. Gender Differences in Pain. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190217518.003.0005.

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Epidemiologic and clinical findings demonstrate that women are at increased risk for chronic pain, experience greater pain-related distress, and show heightened sensitivity for pain compared to men. There are differences in analgesic responses to pain and to both opioid and non-opioid medications as well as for endogenous analgesic processes. Many stress-related disorders, such as fibromyalgia and chronic pain, are more prevalent in women. Studies of experimentally induced pain show that women exhibit greater pain sensitivity, enhanced pain facilitation, and reduced pain inhibition compared to men. Mechanisms that implicated in the underlying sex differences include biological involvement of estrogen and progesterone versus testosterone. Sex-related differences in pain may also reflect differences in the endogenous opioid system. Other mechanisms include steroid action differences in adulthood, modulation of various biological systems such as the cardiovascular and inflammatory pathways, and sociocultural differences
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Stoneley, Sarah, and Simon Rinald. Sensory loss. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0047.

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Sensory disturbance can either be a complete loss (anaesthesia) or a reduction (hypoaesthesia) in the ability to perceive the sensory input. Dysaesthesia is an abnormal increase in the perception of normal sensory stimuli. Hyperalgesia is an increased sensitivity to normally painful stimuli, and allodynia is the perception of usually innocuous stimuli as painful. A complete loss of sensation is likely to be due to a central nervous system problem, while a tingling/paraesthesia (large fibre) or burning/temperature (small fibre) sensation is likely due to an acquired peripheral nervous system problem. Shooting, electric-shock-like pains suggest radicular pathology, a tight-band spinal cord dysfunction. Positive sensory symptoms are usually absent in inherited neuropathies, even in the context of significant deficits on examination. This chapter describes the clinical approach to patients with sensory symptoms. Common patterns of sensory loss and their causes are described.
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Beattie, R. Mark, Anil Dhawan, and John W.L. Puntis. Coeliac disease. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569862.003.0033.

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Who to investigate 234How to investigate 236Diagnosis 238Treatment 240Follow-up and support 242Coeliac disease is an immune-mediated enteropathy caused by a permanent sensitivity to gluten which is present in wheat, barley, and rye. It occurs in genetically susceptible children and adults. The classical presentation is with chronic diarrhoea, abdominal distension, and failure to thrive. The widespread availability of antibody screening has considerably changed the clinical spectrum of cases seen. The testing of children with less classical symptoms and screening of children at high risk has brought increasing recognition of the varied presentation and increased prevalence of this now very common condition....
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Hester, Rebecca J. Culture in Medicine: An Argument Against Competence. Edinburgh University Press, 2018. http://dx.doi.org/10.3366/edinburgh/9781474400046.003.0031.

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For the last few decades cultural competence has been celebrated as the curricular response to a variety of political and social challenges in healthcare. These challenges include the persistence of race- and ethnicity-based health disparities, breakdowns in communication between the patient and provider, and issues of cultural difference around delivery and acceptance of healthcare. Commonly defined as ‘a set of congruent behaviors, attitudes, and policies that come together in a system, agency or among professionals and enable that system, agency or those professions to work effectively in cross-cultural situations’, cultural competence is meant to engender increased sensitivity, humility and awareness with regard to cultural diversity in the clinical context.
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Mc Ardle, Brian A., Jennifer M. Renaud, Robert A. deKemp, and Rob S. B. Beanlands. Role of PET in Diagnosis and Risk Assessment in Patients with Known or Suspected CAD. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0020.

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Cardiac PET enables evaluation of multiple aspects of myocardial perfusion, metabolism, cell signaling and function that are of value both for diagnosis and prognostication in patients with known or suspected CAD and its use has increased in the past three decades. PET myocardial perfusion imaging (MPI) offers several technological advantages over SPECT including; higher photon energy, higher count sensitivity, more consistent attenuation correction and the ability to measure myocardial blood flow in absolute terms. These result in faster imaging times, lower patient radiation exposure and increased diagnostic accuracy. However the availability of PET MPI remains limited, predominantly due to expense. Efforts are underway to expand the use of PET MPI beyond larger centers, with lower-cost scanners and more widely available radiotracers. In this chapter we describe the latest advances in PET camera technology and image reconstruction as well as potential image artifacts specific to PET MPI. We go on to discuss diagnostic accuracy and prognostic value of PET MPI as well as its role in clinical practice.
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Book chapters on the topic "Increased sensitivity"

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Hájek, Karel. "Increased Sensitivity of Ultrasonic Radars for Robotic Use." In Modelling and Simulation for Autonomous Systems, 130–39. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-14984-0_11.

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Zabolotnyi, Oleksandr, and Maksym Sukhobrus. "Sorption-Capacitive Gas Humidity Sensor of Increased Sensitivity." In Lecture Notes in Networks and Systems, 92–101. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-66717-7_8.

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Grzymala-Busse, Jerzy W., and Shantan R. Marepally. "Sensitivity and Specificity for Mining Data with Increased Incompleteness." In Artificial Intelligence and Soft Computing, 355–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13208-7_45.

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Derweesh, Ithaar H., Luis Molto, Charles Tannenbaum, Patricia Rayman, Christina Moon, Cynthia Combs, Thomas Olencki, Paul Elson, Ronald M. Bukowski, and James H. Finke. "Alterations in T-Cell Signaling Pathways and Increased Sensitivity to Apoptosis." In Cancer Immunotherapy at the Crossroads, 119–44. Totowa, NJ: Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-743-7_7.

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Chen, Xi, and Xuanqin Mou. "Conventional Mammographic Image Generation Method with Increased Calcification Sensitivity Based on Dual-Energy." In Breast Imaging, 460–67. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-07887-8_64.

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Petropoulos, Vasileios K., Ioannis K. Petropoulos, and Georgios Verriopoulos. "Adaptations in Aquatic Organisms for Increased Sensitivity to Light and Differences from Humans." In Advances in Experimental Medicine and Biology, 181–86. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-08927-0_20.

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Pilarski, A., J. L. Rose, J. Ditri, D. Jiao, and K. Rajana. "Lamb Wave Mode Selection for Increased Sensitivity to Interfacial Weaknesses of Adhesive Bonds." In Review of Progress in Quantitative Nondestructive Evaluation, 1579–85. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2848-7_202.

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Radin, M. Judith, Bethany J. Holycross, Toni M. Hoepf, and Sylvia A. Mccune. "Increased salt sensitivity secondary to leptin resistance in SHHF rats is mediated by endothelin." In Cardiac Cell Biology, 57–63. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4757-4712-6_8.

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Croizat, Helena, and Ronald L. Nagel. "Increased BPA Production Modulates EPO Sensitivity of Circulating BFU-E in Sickle Cell Anemia." In Advances in Experimental Medicine and Biology, 311–17. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5571-7_34.

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Gammal, Sergio H., Anthony S. Basile, Phil Skolnick, and E. Anthony Jones. "Isolated CNS Neurons from a Model of Hepatic Encephalopathy Exhibit Increased Sensitivity to a Benzodiazepine." In Hepatic Encephalopathy, 295–304. Totowa, NJ: Humana Press, 1989. http://dx.doi.org/10.1007/978-1-4612-4506-3_21.

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Conference papers on the topic "Increased sensitivity"

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Beliaev, M. M., and A. I. Popov. "Increased sensitivity of flow meters." In ТЕНДЕНЦИИ РАЗВИТИЯ НАУКИ И ОБРАЗОВАНИЯ. НИЦ «Л-Журнал», 2018. http://dx.doi.org/10.18411/lj-12-2018-169.

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Nauly, Meutia, and Ridhoi Meilona Purba. "Increased Sensitivity Intercultural Through Culture." In 1st International Conference on Social and Political Development (ICOSOP 2016). Paris, France: Atlantis Press, 2017. http://dx.doi.org/10.2991/icosop-16.2017.23.

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Zlobinskiy, A., and V. Mogilatov. "Increased Sensitivity of Electrical Prospecting." In Engineering and Mining Geophysics 2020. European Association of Geoscientists & Engineers, 2020. http://dx.doi.org/10.3997/2214-4609.202051012.

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Guo, Ke, Min Zhang, Yanbiao Liao, Shurong Lai, Zehan Wang, and Jin Tang. "Fiber-optic hydrophone with increased sensitivity." In SPIE Optics + Photonics. SPIE, 2006. http://dx.doi.org/10.1117/12.679772.

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Sainov, Ventseslav C., Nikola Mechkarov, Assen Shulev, Wim De Waele, Joris Degrieck, and Pierre M. Boone. "Speckle-shear interferometry with increased sensitivity." In 12th International School on Quantum Electronics Laser Physics and Applications, edited by Peter A. Atanasov, Alexander A. Serafetinides, and Ivan N. Kolev. SPIE, 2003. http://dx.doi.org/10.1117/12.519488.

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Barinov, I. N., V. S. Volkov, and S. P. Evdokimov. "The resonance pressure transducer with increased sensitivity." In 2014 International Conference on Actual Problems of Electron Devices Engineering (APEDE). IEEE, 2014. http://dx.doi.org/10.1109/apede.2014.6958209.

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Enge, Amy, and James DiBella. "Accurate color with increased sensitivity using IR." In IS&T/SPIE Electronic Imaging, edited by Ralf Widenhorn, Valérie Nguyen, and Antoine Dupret. SPIE, 2012. http://dx.doi.org/10.1117/12.911281.

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Blouin, Evelyne, Valérie Bougault, Julie Turmel, and Louis-Philippe Boulet. "Increased Methacholine Sensitivity After Eucapnic Voluntary Hyperpnea." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5007.

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van Marwijk-Kooy, M., A. C. Dullemond-Westland, H. C. van Prooijen, M. I. Riemens, and J. W. N. Akkerman. "INCREASED SENSITIVITY OF A PLATELET-SUBPOPULATION TO CRYOPRESERVATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644595.

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When cryopreserved human platelets are stimulated with a high dose of collagen (40 μg/ml), about 50% of the cells fail to aggregate, as measured by counting the disappearance of single platelets. This suggests the presence of a subpopulation with increased susceptibility to cryopreservation-induced cell damage. In an attempt to identify this subfraction fresh platelet suspensions were separated into four size-dependent fractions by counterflow centrifugation. Large platelets (MPV 11.1 μm3 ) better preserved their responsiveness than small platelets (4.2 μm3) with intermediate responses for fractions of 5.7 and 8.0 μm3. In contrast, the partial loss of secretion granules (βTG and PF-4) seen during cryopreservation was greater in the large platelets than in the small cells and did not parallel the differences in aggregability.In a second separation technique the unresponsive fraction was separated from the cells that aggregated with collagen. This fraction consisted of intact cells (LDH), and normal secretion granules (βTG-PF-4) but failed to show changes in Pl-cycle and protein phosphorylation, two essential steps in the activation mechanism of platelets. In accordance with this, the total cryopreserved suspension showed a partial reduction in these second messengers with a 35% lower phosphatidic acid formation, 50-55% less protein phosphorylation and a 50-75% reduction (depending on stimulus concentration) of the liberation of intracellular Ca2+ ions, compared with fresh platelets.Hence, cryopreservation disturbs the activation mechanism of a platelet subpopulation consisting of about 50% of the cells, probably as a result of membrane damage, whereas the other half of the population recovers relatively unharmed from the freeze-thawing procedure.Supported by the Praeventiefund (grant 28953), The Hague.
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Brown, Jeremy A., Kevin Dunphy, Jeff Leadbetter, Rob B. Adamson, and Olivier Beslin. "A single-crystal acoustic hydrophone for increased sensitivity." In ICA 2013 Montreal. ASA, 2013. http://dx.doi.org/10.1121/1.4800731.

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Reports on the topic "Increased sensitivity"

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Korber, Bette. The D614G mutation in Spike: increased infectivity and neutralizing Ab sensitivity and the underlying mechanism. Office of Scientific and Technical Information (OSTI), September 2020. http://dx.doi.org/10.2172/1663165.

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Shy, Daniel. A parameter study to optimizing scintillator characteristics for increased sensitivity in nuclear nonproliferation, safeguards, and security based applications. Office of Scientific and Technical Information (OSTI), August 2014. http://dx.doi.org/10.2172/1186744.

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Driscoll, Donald D. Development and Performance of Detectors for the Cryogenic Dark Matter Search Experiment with an Increased Sensitivity Based on a Maximum Likelihood Analysis of Beta Contamination. Office of Scientific and Technical Information (OSTI), May 2004. http://dx.doi.org/10.2172/875531.

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Research, Gratis. Brown Fat Activation: A Future Treatment for Obesity & Diabetes. Gratis Research, November 2020. http://dx.doi.org/10.47496/gr.blog.01.

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Brown fat holds a promising therapeutic approach to prevent obesity and type 2 diabetes by its profound effects on body weight reduction, heat generation, increased insulin sensitivity and glucose metabolism regulation
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Schery, Stephen D., Wasiolek, Piotr and John Rodgers. Improvement in understanding the deposition of ambient dust particles on ECAM (environmental continuous air monitor) filters, reduction of the alpha-particle interference of radon progeny and other radioactive aerosols in different particle size ranges on filters, and development of ECAMs with increased sensitivity under dusty outdoor conditions. Office of Scientific and Technical Information (OSTI), June 1999. http://dx.doi.org/10.2172/828626.

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Vantassel, Stephen M., and Mark A. Klng. Wildlife Carcass Disposal. U.S. Department of Agriculture, Animal and Plant Health Inspection Service, July 2018. http://dx.doi.org/10.32747/2018.7207733.ws.

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Many wildlife management situations require the disposal of animal carcasses. These can include the lethal removal of wildlife to resolve damage or conflicts, as well as clean-up after mortalities caused by vehicle collisions, disease, oil spills or other natural disasters. Carcasses must be disposed of properly to protect public sensitivities, the environment, and public health. Improper disposal of carcasses can result in public outrage, site contamination, injury to animals and people, and the attraction of other animals that may lead to wildlife damage issues. Concern over ground water contamination and disease transmission from improper carcass disposal has resulted in increased regulation. Successful carcass disposal programs are cost-effective, environmentally sound, and protective of public health. In addition, disposal practices must demonstrate sensitivity to public perception while adhering to state and local guidelines. This publication discusses the range of options available for the responsible disposal of animal carcasses.
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Michalak, Julia, Josh Lawler, John Gross, and Caitlin Littlefield. A strategic analysis of climate vulnerability of national park resources and values. National Park Service, September 2021. http://dx.doi.org/10.36967/nrr-2287214.

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The U.S. national parks have experienced significant climate-change impacts and rapid, on-going changes are expected to continue. Despite the significant climate-change vulnerabilities facing parks, relatively few parks have conducted comprehensive climate-change vulnerability assessments, defined as assessments that synthesize vulnerability information from a wide range of sources, identify key climate-change impacts, and prioritize vulnerable park resources (Michalak et al. In review). In recognition that funding and planning capacity is limited, this project was initiated to identify geographies, parks, and issues that are high priorities for conducting climate-change vulnerability assessments (CCVA) and strategies to efficiently address the need for CCVAs across all U.S. National Park Service (NPS) park units (hereafter “parks”) and all resources. To help identify priority geographies and issues, we quantitatively assessed the relative magnitude of vulnerability factors potentially affecting park resources and values. We identified multiple vulnerability factors (e.g., temperature change, wildfire potential, number of at-risk species, etc.) and sought existing datasets that could be developed into indicators of these factors. To be included in the study, datasets had to be spatially explicit or already summarized for individual parks and provide consistent data for at least all parks within the contiguous U.S. (CONUS). The need for consistent data across such a large geographic extent limited the number of datasets that could be included, excluded some important drivers of climate-change vulnerability, and prevented adequate evaluation of some geographies. The lack of adequately-scaled data for many key vulnerability factors, such as freshwater flooding risks and increased storm activity, highlights the need for both data development and more detailed vulnerability assessments at local to regional scales where data for these factors may be available. In addition, most of the available data at this scale were related to climate-change exposures, with relatively little data available for factors associated with climate-change sensitivity or adaptive capacity. In particular, we lacked consistent data on the distribution or abundance of cultural resources or accessible data on infrastructure across all parks. We identified resource types, geographies, and critical vulnerability factors that lacked data for NPS’ consideration in addressing data gaps. Forty-seven indicators met our criteria, and these were combined into 21 climate-change vulnerability factors. Twenty-seven indicators representing 12 vulnerability factors addressed climate-change exposure (i.e., projected changes in climate conditions and impacts). A smaller number of indictors measured sensitivity (12 indicators representing 5 vulnerability factors). The sensitivity indicators often measured park or landscape characteristics which may make resources more or less responsive to climate changes (e.g., current air quality) as opposed to directly representing the sensitivity of specific resources within the park (e.g., a particular rare species or type of historical structure). Finally, 6 indicators representing 4 vulnerability factors measured external adaptive capacity for living resources (i.e., characteristics of the park and/or surrounding landscape which may facilitate or impede species adaptation to climate changes). We identified indicators relevant to three resource groups: terrestrial living, aquatic living (including living cultural resources such as culturally significant landscapes, plant, or animal species) and non-living resources (including infrastructure and non-living cultural resources such as historic buildings or archeological sites). We created separate indicator lists for each of these resource groups and analyzed them separately. To identify priority geographies within CONUS,...
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Punjabi, Maitri, Julianne Norman, Lauren Edwards, and Peter Muyingo. Using ACASI to Measure Gender-Based Violence in Ugandan Primary Schools. RTI Press, March 2021. http://dx.doi.org/10.3768/rtipress.2021.rb.0025.2104.

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School-related gender-based violence (SRGBV) remains difficult to measure because of high sensitivity and response bias. However, most SRGBV measurement relies on face-to-face (FTF) survey administration, which is susceptible to increased social desirability bias. Widely used in research on sensitive topics, Audio Computer-Assisted Self-Interview (ACASI) allows subjects to respond to pre-recorded questions on a computerized device, providing respondents with privacy and confidentiality. This brief contains the findings from a large-scale study conducted in Uganda in 2019 where primary grade 3 students were randomly selected to complete surveys using either ACASI or FTF administration. The surveys covered school climate, gender attitudes, social-emotional learning, and experiences of SRGBV. Through this study, we find that although most survey responses were comparable between ACASI and FTF groups, the reporting of experiences of sexual violence differed drastically: 43% of students in the FTF group versus 77% of students in the ACASI group reported experiencing sexual violence in the past school term. We also find that factor structures are similar for data collected with ACASI compared with data collected FTF, though there is weaker evidence for construct validity for both administration modes. We conclude that ACASI is a valuable tool in measuring sensitive sub-topics of SRGBV and should be utilized over FTF administration, although further psychometric testing of these surveys is recommended.
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Paynter, Robin A., Celia Fiordalisi, Elizabeth Stoeger, Eileen Erinoff, Robin Featherstone, Christiane Voisin, and Gaelen P. Adam. A Prospective Comparison of Evidence Synthesis Search Strategies Developed With and Without Text-Mining Tools. Agency for Healthcare Research and Quality (AHRQ), March 2021. http://dx.doi.org/10.23970/ahrqepcmethodsprospectivecomparison.

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Background: In an era of explosive growth in biomedical evidence, improving systematic review (SR) search processes is increasingly critical. Text-mining tools (TMTs) are a potentially powerful resource to improve and streamline search strategy development. Two types of TMTs are especially of interest to searchers: word frequency (useful for identifying most used keyword terms, e.g., PubReminer) and clustering (visualizing common themes, e.g., Carrot2). Objectives: The objectives of this study were to compare the benefits and trade-offs of searches with and without the use of TMTs for evidence synthesis products in real world settings. Specific questions included: (1) Do TMTs decrease the time spent developing search strategies? (2) How do TMTs affect the sensitivity and yield of searches? (3) Do TMTs identify groups of records that can be safely excluded in the search evaluation step? (4) Does the complexity of a systematic review topic affect TMT performance? In addition to quantitative data, we collected librarians' comments on their experiences using TMTs to explore when and how these new tools may be useful in systematic review search¬¬ creation. Methods: In this prospective comparative study, we included seven SR projects, and classified them into simple or complex topics. The project librarian used conventional “usual practice” (UP) methods to create the MEDLINE search strategy, while a paired TMT librarian simultaneously and independently created a search strategy using a variety of TMTs. TMT librarians could choose one or more freely available TMTs per category from a pre-selected list in each of three categories: (1) keyword/phrase tools: AntConc, PubReMiner; (2) subject term tools: MeSH on Demand, PubReMiner, Yale MeSH Analyzer; and (3) strategy evaluation tools: Carrot2, VOSviewer. We collected results from both MEDLINE searches (with and without TMTs), coded every citation’s origin (UP or TMT respectively), deduplicated them, and then sent the citation library to the review team for screening. When the draft report was submitted, we used the final list of included citations to calculate the sensitivity, precision, and number-needed-to-read for each search (with and without TMTs). Separately, we tracked the time spent on various aspects of search creation by each librarian. Simple and complex topics were analyzed separately to provide insight into whether TMTs could be more useful for one type of topic or another. Results: Across all reviews, UP searches seemed to perform better than TMT, but because of the small sample size, none of these differences was statistically significant. UP searches were slightly more sensitive (92% [95% confidence intervals (CI) 85–99%]) than TMT searches (84.9% [95% CI 74.4–95.4%]). The mean number-needed-to-read was 83 (SD 34) for UP and 90 (SD 68) for TMT. Keyword and subject term development using TMTs generally took less time than those developed using UP alone. The average total time was 12 hours (SD 8) to create a complete search strategy by UP librarians, and 5 hours (SD 2) for the TMT librarians. TMTs neither affected search evaluation time nor improved identification of exclusion concepts (irrelevant records) that can be safely removed from the search set. Conclusion: Across all reviews but one, TMT searches were less sensitive than UP searches. For simple SR topics (i.e., single indication–single drug), TMT searches were slightly less sensitive, but reduced time spent in search design. For complex SR topics (e.g., multicomponent interventions), TMT searches were less sensitive than UP searches; nevertheless, in complex reviews, they identified unique eligible citations not found by the UP searches. TMT searches also reduced time spent in search strategy development. For all evidence synthesis types, TMT searches may be more efficient in reviews where comprehensiveness is not paramount, or as an adjunct to UP for evidence syntheses, because they can identify unique includable citations. If TMTs were easier to learn and use, their utility would be increased.
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Testing the sensitivity of pumpage to increases in surficial aquifer system heads in the Cypress Creek well-field area, West-Central Florida : an optimization technique. US Geological Survey, 2002. http://dx.doi.org/10.3133/wri024086.

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