Relevant bibliographies by topics / Indice folaire

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  2. Dissertations / Theses
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Academic literature on the topic 'Indice folaire'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Indice folaire"

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Azimi, Sona, Elnaz Faramarzi, Parvin Sarbakhsh, Alireza Ostadrahimi, Mohammad Hossein Somi, and Mousa Ghayour. "Folate and vitamin B12 status and their relation to hematological indices in healthy adults of Iranians: Azar cohort study." Nutrition and Health 25, no. 1 (December 28, 2018): 29–36. http://dx.doi.org/10.1177/0260106018815392.

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Background: Folate and vitamin B12 are essential micronutrients, the deficiency of which can be associated with public health problems worldwide. Aim: The aims of this study were to assess the folate and vitamin B12 status of healthy adults and the effect of gender differences on their deficiency using serum folate, vitamin B12 and red blood cell (RBC) folate as biomarkers and their relation to hematological indices. Methods: This study was a part of the Azar cohort study, which is designed as a noncommunicable disease survey in the population of Shabestar, East Azerbaijan, Iran. A total of 95 healthy adults (35 men, 60 women) were chosen according to exclusion criteria and assessed using demographic characteristics and blood sampling. Results: Low concentrations of serum folate, vitamin B12 and RBC folate were detected in 16.8%, 61.1% and 40% of all subjects, respectively. Prevalence of low serum folate and vitamin B12 was higher in men than women (25.7% versus 11.7% for serum folate, 77.1% versus 51.7% for serum vitamin B12).A significant positive correlation was found between hemoglobin and serum folate, vitamin B12 and RBC folate concentrations ( r = 0.279, 0.335, 0.228, respectively). No statistically significant correlation between mean corpuscular volume and serum folate, vitamin B12 and RBC folate was seen ( r = –0.049, –0.030, –0.016, respectively). Conclusions: There was a high prevalence of low folate and vitamin B12 concentrations in our community. Regarding the impact of these two vitamins deficiency on overall health, we suggest further investigations with more participants. In addition, monitoring hematological indices could be useful in people with folate and vitamin B12 deficiency.
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Glorimar, Pereira, and Trugo. "Longitudinal Change in Plasma Total Homocysteine During Pregnancy and Postpartum in Brazilian Women and its Relation with Folate Status and Other Factors." International Journal for Vitamin and Nutrition Research 74, no. 2 (March 1, 2004): 95–101. http://dx.doi.org/10.1024/0300-9831.74.2.95.

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Abstract: Fasting plasma total homocysteine (tHcy) concentration was determined in a cohort of pregnant Brazilian women (n = 46) supplemented with folic acid from the second trimester of pregnancy. Blood samples were obtained in the first and third trimesters from all women, and 30–40 days postpartum from seventeen women. Plasma tHcy decreased during pregnancy from 10.3 to 8.7 mumol/L, and was 11.6 mumol/L in the postpartum. Plasma and erythrocyte folate increased, consistent with use of the folate supplement, but decreased slightly in the postpartum, whereas the opposite occurred for plasma vitamin B12. tHcy was inversely correlated with plasma and erythrocyte folate in the third trimester (r = –0.585 and –0.460, respectively). This relationship occurred despite the fact that all women had attained what could be considered adequate levels of folate indices. Furthermore, the change (third trimester minus first trimester levels) of tHcy was inversely correlated (p < 0.01) with the changes in plasma (r = –0.573) and erythrocyte folate (r = –0.525). tHcy had no correlation in any of the periods tested with plasma vitamin B12, plasma albumin, hematocrit, hemoglobin, iron indices, dietary intakes of folate, vitamins B12 and B6, and levels of folate supplement.
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Nakhaei, Elnaz, Chan Woo Kim, Daiki Funamoto, Hikari Sato, Yuta Nakamura, Akihiro Kishimura, Takeshi Mori, and Yoshiki Katayama. "Design of a ligand for cancer imaging with long blood circulation and an enhanced accumulation ability in tumors." MedChemComm 8, no. 6 (2017): 1190–95. http://dx.doi.org/10.1039/c7md00102a.

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Yin, Qi, Xiaoying Jin, Guocheng Yang, Chunhuan Jiang, Zhongkai Song, and Guoying Sun. "Biocompatible folate-modified Gd3+/Yb3+-doped ZnO nanoparticles for dualmodal MRI/CT imaging." RSC Adv. 4, no. 96 (2014): 53561–69. http://dx.doi.org/10.1039/c4ra08100e.

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Li, Donghong, Junlin Diao, Dong Wang, Jianchang Liu, and Jiaotao Zhang. "Design, synthesis and biological evaluation of folate-porphyrin: a new photosensitizer for targeted photodynamic therapy." Journal of Porphyrins and Phthalocyanines 14, no. 06 (June 2010): 547–55. http://dx.doi.org/10.1142/s1088424610002379.

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A novel folate-porphyrin conjugate 1 for targeted photodynamic therapy of tumor was designed and synthesized. The results of fluorescence spectroscopy and confocal laser scanning microscope demonstrated that the cellular uptake of conjugate 1 by HeLa cells was 35 times higher than that of precursor porphyrin 3 after 24 h incubation, and that the presence of excessive free folic acid inhibited the cellular uptake of conjugate 1. Cytotoxicity against folate-receptor positive HeLa cells in vitro measured by MTT assay demonstrated that conjugate 1 exhibited much lower dark cytotoxicity but significant photocytotoxicity, with 86.4% of cell growth inhibition ratio after irradiation. However, conjugate 1 induced lower photocytotoxicity for normal cells and folate-receptor negative cells. These results suggest that folate-porphyrin like photosensitizers could induce a potentially useful targeted photodynamic therapy modality for folate-receptor-positive cancer cells due to the folate-receptor mediated endocytosis.
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Li, Wenjie, Jing Shi, Chun Zhang, Min Li, Lu Gan, Huibi Xu, and Xiangliang Yang. "Co-delivery of thioredoxin 1 shRNA and doxorubicin by folate-targeted gemini surfactant-based cationic liposomes to sensitize hepatocellular carcinoma cells." J. Mater. Chem. B 2, no. 30 (2014): 4901–10. http://dx.doi.org/10.1039/c4tb00502c.

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Folate-targeted gemini surfactant-based cationic liposomes are constructed to co-deliver thioredoxin 1 and doxorubicin to inhibit the cell viability and induce apoptosis in hepatocellular carcinoma cells.
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Holm, Jan, and Steen Ingemann Hansen. "Binding of Radiolabeled Folate and 5-Methyltetrahydrofolate to Cow's Milk Folate Binding Protein at pH 7.4 and 5.0. Relationship to Concentration and Polymerization Equilibrium of the Purified Protein." Bioscience Reports 21, no. 6 (December 1, 2001): 733–43. http://dx.doi.org/10.1023/a:1015576522416.

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Binding of folate (pteroylglutamate) and 5-methyltetrahydrofolate, the major endogenous form of folate, to folate binding protein purified from cow's milk was studied at 7°C to avoid degradation of 5-methyltetrahydrofolate. Both folates dissociate rapidly from the protein at pH 3.5, but extremely slowly at pH 7.4, most likely due to drastic changes in protein conformation occurring after folate binding. Dissociation of 5-methyltetrahydrofolate showed no increase at 37°C suggesting that protein-bound-5-methyltetrahydrofolate is protected against degradation. Binding displayed two characteristics, positive cooperativity and a binding affinity that increased with decreasing concentrations of the protein. The binding affinity of folate was somewhat greater than that of 5-methyl tetrahydrofolate, in particular at pH 5.0. Ligand-bound protein exhibited concentration-dependent polymerization (8-mers formed at 13 μM) at pH 7.4. At pH 5.0, only folate-bound forms showed noticeable polymerization. The fact that folate at pH 5.0 surpasses 5-methyltetrahydrofolate both with regard to binding affinity and ability to induce polymerization suggests that ligand binding is associated with conformational changes of the protein which favor polymerization.
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Vynckier, An-Katrien, Dries Ceulemans, Greet Vanheule, Paulien De Mulder, Mieke Van Den Driessche, and Roland Devlieger. "Periconceptional Folate Supplementation in Women after Bariatric Surgery—A Narrative Review." Nutrients 13, no. 5 (May 5, 2021): 1557. http://dx.doi.org/10.3390/nu13051557.

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The prevalence of obesity is increasing globally, and along with it, there is a growing number of patients opting to undergo bariatric surgery to treat this condition. Whilst it has many advantages, bariatric surgery is known to induce micronutrient deficiency, with possible deleterious effects on overall health. This topic becomes even more relevant during pregnancy, where deficiencies can also affect the developing fetus, possibly being the cause of an increase in congenital anomalies. Most notably amongst these micronutrients is folate, or vitamin B9, which plays an essential role in development, gene expression and genomic stability. As insufficient levels of folate are associated with neural tube defects in the fetus, preventing and treating folate deficiencies during pregnancies after bariatric surgery is a relevant issue. Unfortunately, folate supplementation recommendations for bariatric patients who wish to become pregnant are not clear. In this narrative review, we discuss whether the recommendations for the general population are still valid for bariatric patients. Furthermore, we discuss the role of folate in the human body, folate status in both non-bariatric and bariatric patients, the various types of folate that are available for substitution and the risk associated with over-supplementation.
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Bhushan, Bharat, and P. Gopinath. "Tumor-targeted folate-decorated albumin-stabilised silver nanoparticles induce apoptosis at low concentration in human breast cancer cells." RSC Advances 5, no. 105 (2015): 86242–53. http://dx.doi.org/10.1039/c5ra16936d.

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Fuller, Nigel J., Christopher J. Bates, Richard J. Hayes, Andrew K. Bradley, Alice M. Greenwood, Steven Tulloch, and Brian M. Greenwood. "The effects of antimalarials and folate supplements on haematological indices and red cell folate levels in Gambian children." Annals of Tropical Paediatrics 8, no. 2 (June 1988): 61–67. http://dx.doi.org/10.1080/02724936.1988.11748541.

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Dissertations / Theses on the topic "Indice folaire"

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Kaptue, Tchuente Armel. "Cartographie des écosystèmes et paramètres biophysiques satellitaires pour l'étude des flux hydriques sur le continent africain." Toulouse 3, 2010. http://thesesups.ups-tlse.fr/994/.

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Dans le contexte des changements climatiques, l'objectif du travail effectué est de caractériser l'hétérogénéité du continent africain afin de mieux comprendre et quantifier les processus de surface agissant sur les flux hydriques. Ce travail s'inscrit dans le cadre de la mise à jour de la base de données ECOCLIMAP-I constituée d'une carte d'occupation des sols et des cartes de paramètres biophysiques. Pour cela, on s'appuie sur des données de télédétection acquises par les capteurs de dernière génération MODIS et SPOT/VEGETATION entre 2000 et 2007. Dans un premier temps, deux techniques de classification ont été développées afin de cartographier les différents écosystèmes. L'une, supervisée, a été conduite dans le contexte du programme AMMA afin de discriminer les écosystèmes sur la région ouest-africaine en combinant l'information complémentaire contenue dans les cartes d'occupation du sol GLC2000 et ECOCLIMAP-I par analyse supervisée de l'indice foliaire (LAI) MODIS. L'autre, non supervisée et hybride, utilise les principes de regroupement hiérarchique et dynamique de manière automatique en combinant l'usage du classificateur k-NN et celui de la transformée de Fourier Discrète sur la base des données d'indice de végétation normalisé (NDVI) SPOT/VEGETATION pour identifier les écosystèmes africains. Dans un deuxième temps, des méthodes d'estimation des paramètres biophysiques tels que l'albédo, la fraction de végétation, l'indice foliaire ont été développées et/ou appliquées sur le continent. Une approche statistique permet de déterminer la contribution du sol nu et de la végétation à la constitution de l'albédo de surface comme tel que cela est requis dans les modèles de surface. La méthode a d'abord été appliquée sur la région ouest-africaine et sa robustesse a été prouvée lors de son application à l'intégralité du continent africain. Ces conditions de surface ont ensuite été implémentées dans le modèle de surface ISBA pour reproduire les processus de surface. .
In the context of climate change, the aim of this study is to characterize the heterogeneity of the African continent in order to provide some elements to better understand and quantify surfaces process acting on hydric fluxes. This work is intented to update the double ECOCLIMAP-I database which is constituted by a land cover map and a dassets of land biophysical parameters. To this end, we use remotely sensed data acquired by the latest generation sensors MODIS and SPOT/VEGETATION between 2000 and 2007. During the first step, two methods of classifications has been developed for the mapping of different ecosystems. The first method, which is supervised, is obtained by combining information provided by the both global land cover map GLC2000 and ECOCLIMAP-I using an interactive analysis of MODIS leaf area index (LAI). It has been performed in the framework of the AMMA project to discriminate ecosystems over the western African Region. The second method is hybrid in that it combines k-NN clustering, hierarchical principles and the Fast Fourier Transform (FFT) on the basis of multi-annual NDVI data from SPOT/VEGETATION to identify ecosystems at the whole African continent. Then, methods for the estimation of land surface biophysical variables such as albedo, fractional vegetation cover and leaf area index has been developed and/or applied over the mainland. A statistical approach allows us to determine the contribution of bare soil albedo and vegetation albedo to the constitution of albedo as required in land surface models. After the application of the latter approach over the western african region, we demonstrate the robustness of the method by applying it over the entire mainland. The sensitivity of two land surface scenarios was studied by analysing two simulations with the same atmospheric forcing over the western African Region:one using the ECOCLIMAP-I classification and another using the new physiographic forcing specifically developed over the western African region. Heat and latent flux are mainly driven by the fractional vegetation coverage. The land surface model ISBA can be used to predict the impact of land cover change and accordingly the anthropic pressure on hydric fluxes
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Kaptue, Armel. "Cartographie des écosystèmes et paramètres biophysiques satellitaires pour l'étude des flux hydriques sur le continent africain." Phd thesis, Université Paul Sabatier - Toulouse III, 2010. http://tel.archives-ouvertes.fr/tel-00547510.

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Dans le contexte des changements climatiques, l'objectif du travail effectué est de caractériser l'hétérogénéité du continent africain afin de mieux comprendre et quantifier les processus de surface agissant sur les flux hydriques. Ce travail s'inscrit dans le cadre de la mise à jour de la base de données ECOCLIMAP-I constituée d'une carte d'occupation des sols et des cartes de paramètres biophysiques. Pour cela, on s'appuie sur des données de télédétection acquises par les capteurs de dernière génération MODIS et SPOT/VEGETATION entre 2000 et 2007. Dans un premier temps, deux techniques de classification ont été développées afin de cartographier les différents écosystèmes. L'une, supervisée, a été conduite dans le contexte du programme AMMA afin de discriminer les écosystèmes sur la région ouest-africaine en combinant l'information complémentaire contenue dans les cartes d'occupation du sol GLC2000 et ECOCLIMAP-I par analyse supervisée de l'indice foliaire (LAI) MODIS. L'autre, non supervisée et hybride, utilise les principes de regroupement hiérarchique et dynamique de manière automatique en combinant l'usage du classificateur k-NN et celui de la transformée de Fourier Discrète sur la base des données d'indice de végétation normalisé (NDVI) SPOT/VEGETATION pour identifier les écosystèmes africains. Dans un deuxième temps, des méthodes d'estimation des paramètres biophysiques tels que l'albédo, la fraction de végétation, l'indice foliaire ont été développées et/ou appliquées sur le continent. Une approche statistique permet de déterminer la contribution du sol nu et de la végétation à la constitution de l'albédo de surface comme tel que cela est requis dans les modèles de surface. La méthode a d'abord été appliquée sur la région ouest-africaine et sa robustesse a été prouvée lors de son application à l'intégralité du continent africain. Ces conditions de surface ont ensuite été implémentées dans le modèle de surface ISBA pour reproduire les processus de surface. La sensibilité d'ISBA au forçage physiographique a été étudiée en analysant deux simulations avec le même forçage atmosphérique sur la région ouest-africaine : l'une en utilisant la classification ECOCLIMAP-I et l'autre en utilisant la nouvelle paramétrisation de la surface développée sur la région ouest-africaine. Les flux de chaleur latente et sensible sont principalement pilotés par la fraction de végétation. Le modèle ISBA peut être utilisé pour prédire l'impact d'un changement d'occupation du sol et par conséquent des actions anthropiques sur le bilan hydrique.
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Books on the topic "Indice folaire"

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Hodgkiss, Andrew. Psychiatric consequences of cancer treatments: conventional chemotherapy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198759911.003.0006.

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The psychiatric consequences of a range of conventional chemotherapy agents are reviewed. Anti-folates can cause frank demyelination (methotrexate-induced leucoencephalopathy) or more subtle cognitive impairment. The latter is attributed to reduced hippocampal neurogenesis due to the excitotoxic effects of homocysteine. Low mood, due to reduced availability of SAM, is also found during anti-folate chemotherapy. Ifosfamide-induced encephalopathy is described. Depression and encephalopathies are found with mitotic spindle poisons. Procarbazine is considered as a monoamine oxidase inhibitor. Finally, the developing appreciation of the mixed neuropsychiatric actions of bexarotene, an RXR activator, is reviewed.
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Provan, Drew, Trevor Baglin, Inderjeet Dokal, and Johannes de Vos. Red cell disorders. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199683307.003.0002.

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The peripheral blood film in anaemias - Anaemia in renal disease - Anaemia in endocrine disease - Anaemia in joint disease - Anaemia in gastrointestinal disease - Anaemia in liver disease - Iron (Fe) deficiency anaemia - Vitamin B12 deficiency - Folate deficiency - Other causes of megaloblastic anaemia - Anaemia in other deficiency states - Haemolytic syndromes - Genetic control of haemoglobin production - Sickling disorders - HbS—sickle-modifying therapies - Sickle cell trait (HbAS) - Other sickling disorders - Other haemoglobinopathies - Unstable haemoglobins - Thalassaemias - α thalassaemia - β thalassaemia - Other thalassaemias - Hereditary persistence of fetal haemoglobin - Hb patterns in haemoglobin disorders - Non-immune haemolysis - Hereditary spherocytosis - Hereditary elliptocytosis - Glucose-6-phosphate dehydrogenase (G6PD) deficiency - Pyruvate kinase deficiency - Other red cell enzymopathies - Drug-induced haemolytic anaemia - Methaemoglobinaemia - Microangiopathic haemolytic anaemia - Acanthocytosis - Autoimmune haemolytic anaemia - Cold haemagglutinin disease - Leucoerythroblastic anaemia - Aplastic anaemia - Paroxysmal nocturnal haemoglobinuria - Pure red cell aplasia - Iron (Fe) overload - Transfusion haemosiderosis
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Provan, Drew, Trevor Baglin, Inderjeet Dokal, Johannes de Vos, Banu Kaya, and Angela Theodoulou. Red cell disorders. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199683307.003.0002_update_001.

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The peripheral blood film in anaemias - Anaemia in renal disease - Anaemia in endocrine disease - Anaemia in joint disease - Anaemia in gastrointestinal disease - Anaemia in liver disease - Iron (Fe) deficiency anaemia - Vitamin B12 deficiency - Folate deficiency - Other causes of megaloblastic anaemia - Anaemia in other deficiency states - Haemolytic syndromes - Genetic control of haemoglobin production - Sickling disorders - HbS—sickle-modifying therapies - Sickle cell trait (HbAS) - Other sickling disorders - Other haemoglobinopathies - Unstable haemoglobins - Thalassaemias - α‎ thalassaemia - β‎ thalassaemia - Other thalassaemias - Hereditary persistence of fetal haemoglobin - Hb patterns in haemoglobin disorders - Non-immune haemolysis - Hereditary spherocytosis - Hereditary elliptocytosis - Glucose-6-phosphate dehydrogenase (G6PD) deficiency - Pyruvate kinase deficiency - Other red cell enzymopathies - Drug-induced haemolytic anaemia - Methaemoglobinaemia - Microangiopathic haemolytic anaemia - Acanthocytosis - Autoimmune haemolytic anaemia - Cold haemagglutinin disease - Leucoerythroblastic anaemia - Aplastic anaemia - Paroxysmal nocturnal haemoglobinuria - Pure red cell aplasia - Iron (Fe) overload - Transfusion haemosiderosis
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Book chapters on the topic "Indice folaire"

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Bhide, Prajkta. "Neural Tube Defects and Folate Status in India." In Birth Defects in India, 235–49. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-1554-2_10.

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Middleton, Stephen J., and Raymond J. Playford. "Bacterial overgrowth of the small intestine." In Oxford Textbook of Medicine, edited by Jack Satsangi, 2879–83. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0299.

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Small intestinal bacterial overgrowth can be defined as the presence of excessive bacteria in the small intestine which can interfere with digestion and absorption. Predisposing causes include sustained hypochlorhydria induced by proton pump inhibitors, small intestinal dysmotility and stasis due to anatomical or motor abnormalities, and reduced antibacterial activity as seen in immunological deficiency and chronic pancreatitis. Presentation is predominantly from consequences of malabsorption, including gastrointestinal symptoms (e.g. diarrhoea or steatorrhoea) and features of specific nutrient malabsorption (e.g. osteoporosis, anaemia, neuropathy, and night blindness). Definitive diagnosis is difficult, requiring a properly collected and appropriately cultured aspirate from the proximal small intestine revealing a total concentration of a mixed growth of bacteria generally greater than 105 organisms/ml. Alternative investigations frequently used include glucose/lactulose breath tests or either the 13C- or 14C-xylose breath test, with elevated levels of 13CO2 or 14CO2 found in the breath. There may be low levels of cobalamin (metabolized by Gram-negative anaerobes), increased serum folate (synthesized by overgrowth flora), and increased urinary indicans (intraluminal product of bacterial tryptophan metabolism). Aside from treatment of any nutritional deficiencies, specific treatment is with an antimicrobial that is effective against both aerobic and anaerobic enteric bacteria (e.g. doxycycline, amoxicillin–clavulanic acid, rifaximin, or ciprofloxacin), which can be administered in rotation to reduce antibiotic resistance. Where possible and appropriate, correction of any underlying cause should also be performed.
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Conference papers on the topic "Indice folaire"

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Ho, Chun-Te, Tsan-Zon Liu, Yu-Ting Chou, Shih-Hsin Hsiao, and Jun-Jen Liu. "Abstract 4970: Folate metabolism defect induce invasion and Gefinitib resistance in lung cancer." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-4970.

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Wen, Yun-Fei, and Anil K. Sood. "Abstract 3817: Suicidal autophagy induced by immunotherapy targeting folate receptor in ovarian cancer." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-3817.

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