Dissertations / Theses on the topic 'Indices de De Bruijn'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'Indices de De Bruijn.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Pouillard, Nicolas. "Une approche unifiante pour programmer sûrement avec de la syntaxe du premier ordre contenant des lieurs." Phd thesis, Université Paris-Diderot - Paris VII, 2012. http://tel.archives-ouvertes.fr/tel-00759059.
Full textEvans, Stephen David. "Methods of rapid bruise assessment and the formulation of robust bruise indices for potatoes." Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/27990.
Full textVarnet, Léo. "Identification des indices acoustiques utilisés lors de la compréhension de la parole dégradée." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10221/document.
Full textThere is today a broad consensus in the scientific community regarding the involvement of acoustic cues in speech perception. Up to now, however, the precise mechanisms underlying the transformation from continuous acoustic stream into discrete linguistic units remain largely undetermined. This is partly due to the lack of an effective method for identifying and characterizing the auditory primitives of speech. Since the earliest studies on the acoustic–phonetic interface by the Haskins Laboratories in the 50’s, a number of approaches have been proposed; they are nevertheless inherently limited by the non-naturalness of the stimuli used, the constraints of the experimental apparatus, and the a priori knowledge needed. The present thesis aimed at introducing a new method capitalizing on the speech-in-noise situation for revealing the acoustic cues used by the listeners.As a first step, we adapted the Classification Image technique, developed in the visual domain, to a phoneme categorization task in noise. The technique relies on a Generalized Linear Model to link each participant’s response to the specific configuration of noise, on a trial-by-trail basis, thereby estimating the perceptual weighting of the different time-frequency regions for the decision. We illustrated the effectiveness of our Auditory Classification Image method through 2 examples: a /aba/-/ada/ categorization and a /da/-/ga/ categorization in context /al/ or /aʁ/. Our analysis confirmed that the F2 and F3 onsets were crucial for the tasks, as suggested in previous studies, but also revealed unexpected cues. In a second step, we relied on this new method to compare the results of musical experts (N=19) or dyslexics participants (N=18) to those of controls. This enabled us to explore the specificities of each group’s listening strategies.All the results taken together show that the Auditory Classification Image method may be a more precise and more straightforward approach to investigate the mechanisms at work at the acoustic-phonetic interface
Löthgren, Anders. "de Bruijn-sekvenserDet effektiva paketbudet." Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-36148.
Full textBryant, Roy Dale. "Covering the de Bruijn graph." Thesis, Monterey, California. Naval Postgraduate School, 1986. http://hdl.handle.net/10945/21751.
Full textHunt, D'Hania J. "Constructing higher-order de Bruijn graphs." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2002. http://library.nps.navy.mil/uhtbin/hyperion-image/02Jun%5FHunt.pdf.
Full textThesis advisor(s): Harold Fredricksen, Craig W. Rasmussen. Includes bibliographical references (p. 45-46). Also available online.
Alharthy, Shathaa. "De Bruijn Graphs and Lamplighter Groups." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/38832.
Full textKrahn, Gary William. "Double Eulerian cycles on de Bruijn digraphs." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 1994. http://handle.dtic.mil/100.2/ADA283334.
Full textDissertation supervisor(s): Harold Fredricksen. "June 1994" Includes bibliographical references. Also available online.
Popovic, Lada McEliece Robert J. McEliece Robert J. "Finite state codes and generalized De Bruijn sequences /." Diss., Pasadena, Calif. : California Institute of Technology, 1991. http://resolver.caltech.edu/CaltechETD:etd-07092007-131600.
Full textZerbino, Daniel Robert. "Genome assembly and comparison using de Bruijn graphs." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611752.
Full textLyman, Cole Andrew. "Comparative Genomics Using the Colored de Bruijn Graph." BYU ScholarsArchive, 2020. https://scholarsarchive.byu.edu/etd/8441.
Full textBadr, Eman. "Identifying Splicing Regulatory Elements with de Bruijn Graphs." Diss., Virginia Tech, 2015. http://hdl.handle.net/10919/73366.
Full textPh. D.
Feng, Zhi. "Optical MANs based on the de Bruijn graph." Thesis, University of Ottawa (Canada), 1994. http://hdl.handle.net/10393/6647.
Full textLeiba, Raphaël. "Conception d'un outil de diagnostic de la gêne sonore en milieu urbain." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066602/document.
Full textNoise, especially road traffic noise, is cited by many studies as a source of major societal concern. So far, public responses are based only on energy quantification of sound exposure, often by measuring or estimating LA or Lden, and sound-level reduction related decision are taken. Nevertheless, psychoacoustic studies have shown that the sound level explains only a small part of the perceived noise annoyance. It is interesting to have more information about the source of noise and not to reduce the information to its sound level. In this thesis a tool is proposed for estimating the noise annoyance induced by each road vehicle using its audio signal and noise annoyance models. To do so, the audio signal of the vehicle is isolated by using inverse methods, large microphones arrays and image processing to obtain its trajectory. The knowledge of the trajectory and of the signal allows the vehicle to be classified by a machine learning method according to Morel et al. taxonomy. Once its category obtained, the specific annoyance of the vehicle is estimated thanks to a noise annoyance model using psychoacoustic and energetic indices. This allows the estimation of specific noise annoyance for each vehicle within the road traffic. The application of this method is made during a measurement day on a large Parisian artery
Poirier, Carl. "Assemblage d'ADN avec graphes de de Bruijn sur FPGA." Master's thesis, Université Laval, 2015. http://hdl.handle.net/20.500.11794/27132.
Full textHines, Peter Anthony. "The linear complexity of de Bruijn sequences over finite fields." Thesis, Royal Holloway, University of London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313736.
Full textPeng, Yu, and 彭煜. "Iterative de Bruijn graph assemblers for second-generation sequencing reads." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B50534051.
Full textpublished_or_final_version
Computer Science
Doctoral
Doctor of Philosophy
Eduardo, Moreno. "Graphes et cycles de de Bruijn dans des langages avec des restrictions." Phd thesis, Université de Marne la Vallée, 2005. http://tel.archives-ouvertes.fr/tel-00628709.
Full textMoreno, Eduardo. "Graphes et cycles de de Bruijn dans des langages avec des restrictions." Marne-la-Vallée, 2005. https://tel.archives-ouvertes.fr/tel-00628709.
Full textLet be a language composed by all words of a given length n. A de Bruijn sequence of span n is a cyclic string such that all words in the language appears exactly once as factors of this sequence. One of the algorithms to construct the lexicographically minimal de Bruijn sequence is due to Fredricksen and Maiorana and it use the Lyndon words in the language. This thesis studies how to generalize the concept of de Bruijn sequence for a language composed by a subset of words of length n, particularly the languages of all words of length n without factors in a list of forbidden factors. Firstly, we study the case of words without the factor 11. We give a new proof of the algorithm of Fredricksen and Maiorana which allows us to extend this result to the case of words without the factor 1i for any i. We characterize for which languages of words of length n exists a de Bruijn sequence, and we also study some symbolic dynamical properties of these languages, particularly of the languages defined by forbidden factors. For these kinds of languages, we present an algorithm to produce a de Bruijn sequence, using the Lyndon words of the language. These results use the notion of de Bruijn graph and reduce the problem to construct an Eulerian cycle in this graph. We study the problem of construct the lexicographically minimal de Bruijn sequence in a language with forbidden factors using the de Bruijn graph. We study two algorithms, a simple and efficient greedy algorithm which works with some sets of languages, and a more complex algorithm which solves this problem for any Eulerian labelled graph
Richard, Céline. "Etude de l’encodage des sons de parole par le tronc cérébral dans le bruit." Thesis, Lyon 2, 2010. http://www.theses.fr/2010LYO20116/document.
Full textThe major purpose of my thesis was the investigation of brainstem structures implications into speech in noise processing, particularly by identifying the impact of acoustic cues on normal speech perception. Firstly, we were involved in the engineering of the speech auditory brainstem responses (SABR) recording system. SABR are similar to brainstem auditory evoked responses to clicks, but require different acquisition and signal processing set-ups, due to the difference between the French and the American stimuli used by the American reference team. The different studies presented here, permitted to emphasize the role of brainstem structures into the subcortical processing of acoustical cues, such as the temporal enveloppe, or the voicing, with a possible evidence of a corticofugal effect on SABR. These experimentations lead us to a more fundamental question on the best conditions required for PEASP collection, in particular, the best stimulation intensity needed. The results of the experiment on intensity effect showed a non linear relation between the stimulation intensity and PEASP characteristics. Even if an intensity of only 20 dB SL seems enough for SABR recording, individual results are still highly variable so that diagnostic application of SABR on, for example, children with language learning problems or subject suffering from speech in noise perception impairment remains difficult
Zeineddine, Hassan. "Effect of limited wavelength conversion in all-optical networks based on de Bruijn graphs." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0010/MQ52494.pdf.
Full textVentura, Daniel Lima. "Cálculos de substituições explícitas à la de Bruijn com sistemas de tipos com interseção." reponame:Repositório Institucional da UnB, 2010. http://repositorio.unb.br/handle/10482/8787.
Full textSubmitted by Jaqueline Ferreira de Souza (jaquefs.braz@gmail.com) on 2011-06-29T20:20:12Z No. of bitstreams: 1 2010_DanielLimaVentura.pdf: 943550 bytes, checksum: 33a595d3777e87c528eaa8917894eba0 (MD5)
Approved for entry into archive by Jaqueline Ferreira de Souza(jaquefs.braz@gmail.com) on 2011-06-29T20:25:33Z (GMT) No. of bitstreams: 1 2010_DanielLimaVentura.pdf: 943550 bytes, checksum: 33a595d3777e87c528eaa8917894eba0 (MD5)
Made available in DSpace on 2011-06-29T20:25:33Z (GMT). No. of bitstreams: 1 2010_DanielLimaVentura.pdf: 943550 bytes, checksum: 33a595d3777e87c528eaa8917894eba0 (MD5)
O calculus é um modelo teórico de computação tão antigo quanto a própria noção de função computável. Devido a definição da substituição como uma metaoperação. existem várias formas de tornar esta substituição explícita no sistema, dando surgimento a uma grande variedade de sistemas baseados no calculus. Estudamos dois cálculos de substituições explícitas, o e o se, com sistemas de tipos com interseção. Estes cálculos utilizam uma notação à la de Bruijn, onde variáveis são representadas por índices ao invés de nomes. Sistemas de atribuição de tipos permitem uma análise sintática (estática) de propriedades semânticas (dinâmicas) de programas, dispensando qualquer declaração de tipos dentro destes. Os tipos com interseção apresentam uma maneira de integrar polimorfismo ao sistema, que tem se mostrado conveniente computacionalmente com propriedades como a tipagem principal, que permite, e.g a compilação separada e a recompilação inteligente para o sistema de tipos computacionais. Para a adição de tipos com interseção aos cálculos estudados, fazemos um estudo do calculus à la de Bruijn com dois sistemas de tipos diferentes. Uma caracterização sintática de tipagens principais, para termos irredutíveis, em um dos sistemas é apresentada. Baseado neste sistema, introduzimos sistemas de tipos com interseção para e o se. A propriedade básica de redução de sujeito, que garante a preservação dos tipos em qualquer computação possível para termos tipáveis, é analisada nas variações dos sistemas propostos. Outra propriedade analisada é a relevância do sistema, garantindo que apenas a informação de tipos necessária para inferência é utilizada, impossibilitando a admissibilidade de uma lei de redundância para o sistema de tipos. ______________________________________________________________________________________ ABSTRACT
The ג-calculus is a well known theoretical computation model as old as the concept of computable functions. Due to the substitution definition as a meta-operator there exists a great quantity of variations of this computational system in which the operation of substitution is treated explicitly. In this work we investigate intersection type systems for two explicit substitution calculi, the גσ and the גse, both with de Bruijn indices. Type assignment systems allow one to have a static code analysis through implicit typing inference, where no type declaration is required. Intersection types present a machine friendly way to add polymorphism to type systems with features such as the principal typing property, allowing e.g. a separate compilation and the smartest recompilation. We study the ג–calculus with de Bruijn indices with two diferente type systems, in a preliminary step for adding intersection types for both explicit substitution calculi. A characterisation for principal typÃngs of irreducibe terms is a given in on of the systems, wich the intersection type systems for each גσ and גse are basead on. We analyse the subject reduction property, which guarantees that all terms of the system preserve their types during any possible computation, in some variations for the proposed type systems. Another analysed property is the relevance, in which only necessary suppositions are allowed in a typing inference, turning a weakening rule inadmissible in the type system.
House, Margaret A. "Water quality indices." Thesis, Middlesex University, 1986. http://eprints.mdx.ac.uk/13379/.
Full textKhani, Hossein. "Ordinal Power Indices." Thesis, Université Paris sciences et lettres, 2020. http://www.theses.fr/2020UPSLD025.
Full textThe design of procedures aimed at ranking individuals according to how they behave in various groups is of great importance in many practical situations. The problem occurs in a variety of scenarios coming from social choice theory,cooperative game theory or multi-attribute decision theory, and examples include: comparing researchers in a scientificdepartment by taking into account their impact across different teams; finding the most influential political parties in aparliament based on past alliances within alternative majority coalitions; rating attributes according to their influence ina multi-attribute decision context, where independence of attributes is not verified because of mutual interactions. However, in many real world applications, a precise evaluation on the coalitions’ “power” may be hard for many reasons (e.g., uncertain data, complexity of the analysis, missing information or difficulties in the update, etc.). In this case, it may be interesting to consider only ordinal information concerning binary comparisons between coalitions. The main objectiveof this thesis is to study the problem of finding an ordinal ranking over the set N of individuals (called social ranking),given an ordinal ranking over its power set (called power relation). In order to do that, during the thesis we use notionsin classical voting theory and cooperative game theory. Mainly, we have defined solution concepts named ceteris paribusmajority rule, and ordinal Banzhad index, which are respectively inspired from classical voting theory and cooperativegame theory. Since the majority of our work in the thesis is to study solutions from property-driven approach, we axiomatically study the solutions by reformulating axioms in classical voting theory. Finally, exploring weighted extensionsof the ceteris paribus majority rule to rank more than two individuals result in an axiomatic study of families of weightedsolutions
Casselryd, Linnéa, Agnes Lantto, and Alicia Julienne Zanic. "MSCI Climate Paris Aligned Indices : A quantitative study comparing the performance of SR indices and their conventional benchmark indices." Thesis, Umeå universitet, Företagsekonomi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-185021.
Full textDaniel, Frédéric. "Sur les communications globales dans les réseaux à topologie de de Bruijn et de Kautz." Toulouse 3, 1996. http://www.theses.fr/1996TOU30248.
Full textHanegan, Andrew Aaron. "Industrial energy use indices." Texas A&M University, 2007. http://hdl.handle.net/1969.1/85849.
Full textCrawford, Ian Anderson. "Cost of living indices." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286226.
Full textLouzas, Andre Luiz da Conceição. "Cidades : floresta de indices." [s.n.], 2004. http://repositorio.unicamp.br/jspui/handle/REPOSIP/284878.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Artes
Made available in DSpace on 2018-08-03T22:54:28Z (GMT). No. of bitstreams: 1 Louzas_AndreLuizdaConceicao_M.pdf: 23363930 bytes, checksum: 552c0446f0ff7c443d72fa75235c4d28 (MD5) Previous issue date: 2004
Mestrado
Florio, Anna. "Indices de Maslov asymptotiques." Thesis, Avignon, 2019. http://www.theses.fr/2019AVIG0422.
Full textWe study the asymptotic Maslov index for surface diffeomorphisms. Roughly speaking,this quantity is the limit of the average rotational velocity of tangent vectors which evolveunder the action of the differential of the diffeomorphism. For twist maps on the annulus,we prove that the set of points of zero index has Hausdorff dimension at least one. In theframework of conservative twist maps, we show that every bounded instability region has apositive Lebesgue measure set of points with non zero index. Finally, we study such indexin the presence of periodic hyperbolic points with transverse homoclinic intersections,providing examples of points at which the asymptotic Maslov index does not exist
Carvalho, Luís Filipe Cordeiro. "Do market indices overreact?" Master's thesis, Instituto Superior de Economia e Gestão, 2019. http://hdl.handle.net/10400.5/19756.
Full textEntende-se por sobreajustamento de mercado quando o optimismo (pessimismo) por parte dos investidores leva a que o preço da ação de uma empresa suba (desça) de tal forma que esta é considerada vencedora (perdedora), num período compreendido de 3 a 5 anos. Esta dissertação estuda a hipótese de sobreajustamento nos índices de mercado. Utilizando dados mensais de dezembro 1970 a dezembro 2018 de 49 índices internacionais da Morgan Stanley Capital, foi estudada a hipótese de sobreajustamento nos índices de Mercado para períodos de 3 e 5 anos. Ao invés de retornos cumulativos os retornos foram calculados segundo a metodologia de investimento passivo com o intuito de evitar enviesamentos. Foram encontradas fortes reversões dos retornos para períodos de investimento de 3 anos, e estatisticamente significativos. Quando implementada a estratégia de comprar os maiores perdedores e vender os maiores vencedores apenas em índices de mercados desenvolvidos, encontra-se igualmente evidência para a hipótese de sobreajustamento, ainda que os retornos sejam menos expressivos do ponto de vista económico. Foi igualmente encontrada evidência para a hipótese de sobreajustamento quando se considera períodos de investimento de 5 anos, com resultados estatisticamente significativos. Os perdedores não só têm rendibilidades superiores aos ganhadores, como apresentam menos risco. Independentemente do período de investimento, anos da amostra ou do tipo de mercado o Beta do portfólio de perdedores foi, em média, inferior ao do portfólio de vencedores. Não obstante estes resultados, a hipótese de sobreajustamento aparenta não ser estacionária no tempo.
Investors are told to be overreacting when their sentiment drives the price of a certain security up (down) enough to make it the biggest winner (loser), in most cases considering this overreaction period as long as 3 or 5 years. This dissertation studies the overreaction hypothesis in market indices. Using end of month data from December 1970 to December 2018 from 49 Morgan Stanley Capital International Indices we studied the overreaction hypothesis on Market Indices for 3- and 5-years investment periods. Instead of Cumulative Average Returns the returns were computed as Holding Period Returns to avoid the upward bias. We found strong return reversals for 3-year investment periods, which were statistically significant at a 5% significant level. However, the returns might be weaker depending on the time period we consider. When implemented only in developed markets there is still evidence supporting the overreaction hypothesis, although the excess returns are economically weaker. Evidence for the overreaction hypothesis was also found when 5-year investment periods were considered. Not only did losers outperform winners, but they were also less risky than winners. Regardless of the market, investment period and/or time-period considered, losers' portfolio beta was always smaller than the winners' portfolio beta. Notwithstanding these results, the overreaction strategy is sensitive to the time periods considered which highlights the possibility that the overreaction strategy success it's not time stationary.
info:eu-repo/semantics/publishedVersion
LIMA, Jamerson Felipe Pereira. "Representações cache eficientes para montagem de fragmentos baseada em grafos de de Bruijn de sequências biológicas." Universidade Federal de Pernambuco, 2017. https://repositorio.ufpe.br/handle/123456789/25352.
Full textApproved for entry into archive by Alice Araujo (alice.caraujo@ufpe.br) on 2018-08-02T20:09:33Z (GMT) No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Jamerson Felipe Pereira Lima.pdf: 1541250 bytes, checksum: ccefce36b254aed5273279c3a4600f9f (MD5)
Made available in DSpace on 2018-08-02T20:09:33Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Jamerson Felipe Pereira Lima.pdf: 1541250 bytes, checksum: ccefce36b254aed5273279c3a4600f9f (MD5) Previous issue date: 2017-02-20
FACEPE
O estudo dos genomas dos seres vivos têm sido impulsionado pelos avanços na biotecnologia ocorridos desde a segunda metade do Séc. XX. Particularmente, o desenvolvimento de novas plataformas de sequenciamento de alto desempenho ocasionou a proliferação de dados brutos de fragmentos de sequências nucleicas. Todavia, a montagem dos fragmentos de DNA continua a ser uma das etapas computacionais mais desafiadoras, visto que a abordagem tradicional desse problema envolve a solução de problemas intratáveis sobre grafos obtidos a partir dos fragmentos, como, por exemplo, a determinação de caminhos hamiltonianos. Mais recentemente, soluções baseadas nos grafos de de Bruijn (gdB), também obtidos a partir dos fragmentos sequenciados, têm sido adotadas. Nesse caso, o problema da montagem relaciona-se com o de encontrar caminhos eulerianos, o qual possui soluções polinomiais conhecidas. Embora apresentem custo computacional teórico mais baixo, ainda demandam, na prática, grande poder computacional, face ao volume de dados envolvido. Por exemplo, a representação empregada por algumas ferramentas para o gdB do genoma humano pode alcançar centenas de gigabytes. Faz-se necessário, portanto, o emprego de técnicas algorítmicas para manipulação eficiente de dados em memória interna e externa. Nas arquiteturas computacionais modernas, a memória é organizada de forma hierárquica em camadas: cache, memória RAM, disco, rede, etc. À medida que o nível aumenta, cresce a capacidade de armazenagem, porém também o tempo de acesso. O ideal, portanto, seria manter a informação limitada o mais possível aos níveis inferiores, diminuindo a troca de dados entre níveis adjacentes. Para tal, uma das abordagens são os chamados algoritmos cache-oblivious, que têm por objetivo reduzir o número de trocas de dados entre a memória cache e a memória principal sem que seja necessário para tanto introduzir parâmetros relativos à configuração da memória ou instruções para a movimentação explícita de blocos de memória. Uma outra alternativa que vêm ganhando ímpeto mais recentemente é o emprego de estruturas de dados ditas sucintas, ou seja, estruturas que representam a informação usando uma quantidade ótima de bits do ponto de vista da teoria da informação. Neste trabalho, foram implementadas três representações para os gdB, com objetivo de avaliar seus desempenhos em termos da utilização eficiente da memória cache. A primeira corresponde a uma implementação tradicional com listas de adjacências, usada como referência, a segunda é baseada em estruturas de dados cache-oblivious, originalmente descritas para percursos em grafos genéricos, e a terceira corresponde a uma representação sucinta específica para os gdB, com otimizações voltadas ao melhor uso da cache. O comportamento dessas representações foi avaliado quanto à quantidade de acessos à memória em dois algoritmos, nomeadamente o percurso em profundidade (DFS) e o tour euleriano. Os resultados experimentais indicam que as versões tradicional e cache-oblivious genérica apresentam, nessa ordem, os menores números absolutos de cache misses e menores tempos de execução para dados pouco volumosos. Entretanto, a versão sucinta apresenta melhor desempenho em termos relativos, considerando-se a proporção entre o número de cache misses e a quantidade de acessos à memória, sugerindo melhor desempenho geral em situações extremas de utilização de memória.
The study of genomes was boosted by advancements in biotechnology that took place since the second half of 20th century. In particular, the development of new high-throughput sequencing platforms induced the proliferation of nucleic sequences raw data. Although, DNA assembly, i.e., reconstitution of original DNA sequence from its fragments, is still one of the most computational challenging steps. Traditional approach to this problem concerns the solution of intractable problems over graphs that are built over the fragments, as the determination of Hamiltonian paths. More recently, new solutions based in the so called de Bruijn graphs, also built over the sequenced fragments, have been adopted. In this case, the assembly problem relates to finding Eulerian paths, for what polynomial solutions are known. However, those solutions, in spite of having a smaller computational cost, still demand a huge computational power in practice, given the big amount of data involved. For example, the representation employed by some assembly tools for a gdB of human genome may reach hundreds of gigabytes. Therefore, it is necessary to apply algorithmic techniques to efficiently manipulate data in internal and external memory. In modern computer architectures, memory is organized in hierarchical layers: cache, RAM, disc, network, etc. As the level grows, the storage capacity is also bigger, as is the access time (latency). That is, the speed of access is smaller. The aim is to keep information limited as much as possible in the highest levels of memory and reduce the need for block exchange between adjacent levels. For that, an approach are cache-oblivious algorithms, that try to reduce the the exchange of blocks between cache and main memory without knowing explicitly the physical parameters of the cache. Another alternative is the use of succinct data structures, that store an amount of data in space close to the minimum information-theoretical. In this work, three representations of the de Bruijn graph were implemented, aiming to assess their performances in terms of cache memory efficiency. The first implementation is based in a traditional traversal algorithm and representation for the de Bruijn graph using adjacency lists and is used as a reference. The second implementation is based in cache-oblivious algorithms originally described for traversal in general graphs. The third implementation is based in a succinct representation of the de Bruijn graph, with optimization for cache memory usage. Those implementations were assessed in terms of number of accesses to cache memory in the execution of two algorithms, namely depth-first search (DFS) and Eulerian tour. Experimental results indicate that traditional and generic cache-oblivious representations show, in this order, the least absolute values in terms of number of cache misses and least times for small amount of data. However, the succinct representation shows a better performance in relative terms, when the proportion between number of cache misses and total number of access to memory is taken into account. This suggests that this representation could reach better performances in case of extreme usage of memory.
Rudewicz, Justine. "Méthodes bioinformatiques pour l'analyse de données de séquençage dans le contexte du cancer." Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0635/document.
Full textCancer results from the excessive proliferation of cells decending from the same founder cell and following a Darwinian process of diversification and selection. This process is defined by the accumulation of genetic and epigenetic alterations whose characterization is a key element for establishing a therapy that would specifically target tumor cells. The advent of new high-throughput sequencing technologies enables this characterization at the molecular level. This technological revolution has led to the development of numerous bioinformatics methods. In this thesis, we are particularly interested in the development of new computational methods for the analysis of sequencing data of tumor samples allowing precise identification of tumor-specific alterations and an accurate description of tumor subpopulations. In the first chapter, we explore methods for identifying single nucleotide alterations in targeted sequencing data and apply them to a cohort of breast cancer patients. We introduce two new methods of analysis, each tailored to a particular sequencing technology, namely Roche 454 and Pacific Biosciences. In the first case, we adapted existing approaches to the particular case of transcript sequencing. In the second case, when using conventional approaches, we were confronted with a high background noise resulting in a high rate of false positives. We have developed a new method, MICADo, based on the De Bruijn graphs and making possible an effective distinction between patient-specific alterations and alterations common to the cohort, which makes the results usable in a clinical context. Second chapter deals with the identification of copy number alterations. We describe the approach put in place for their efficient identification from very low coverage data. The main contribution of this work is the development of a strategy for statistical analysis in order to emphasise local and global changes in the genome that occurred during the treatment administered to patients with breast cancer. Our method is based on the construction of a linear model to establish scores of differences between samples before and after treatment. In the third chapter, we focus on the problem of clonal reconstruction. This problem has recently gathered a lot of interest, but it still lacks a well-established formal framework. We first propose a formalization of the clonal reconstruction problem. Then we use this formalism to put in place a method based on Gaussian mixture models. Our method uses single nucleotide and copy number alterations - such as those discussed in the previous two chapters - to characterize and quantify different clonal populations present in a tumor sample
Green, Shawn Jeffrey. "Extensions of the Power Group Enumeration Theorem." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/7526.
Full textDemazeau, Yves. "Niveaux de représentation pour la vision par ordinateur : indices d'image et indices de scène." Phd thesis, Grenoble INPG, 1986. http://tel.archives-ouvertes.fr/tel-00322886.
Full textDemazeau, Yves. "Niveaux de représentation pour la vision par ordinateur indices d'image et indices de scène." Grenoble 2 : ANRT, 1986. http://catalogue.bnf.fr/ark:/12148/cb37597056c.
Full textDemazeau, Yves Latombe Jean-Claude. "Niveaux de représentation pour la vision par ordinateur indices d'image et indices de scène /." S.l. : Université Grenoble 1, 2008. http://tel.archives-ouvertes.fr/tel-00322886.
Full textChristie, Gregory J., and University of Lethbridge Faculty of Arts and Science. "Electrophysiological indices of feedback processing." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, 2010, 2010. http://hdl.handle.net/10133/2551.
Full textxii, 76 leaves : ill. (chiefly col.) ; 29 cm
Etowa, Christian Bassey. "Inherently safer process design indices." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/MQ63510.pdf.
Full textRhodes, Peter. "Indices of nitric oxide production." Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307982.
Full textParker, Jonathan Duguid Edward. "Environmental reporting and environmental indices." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358483.
Full textSüss, Stephan. "Volatility indices and their derivatives /." [S.l.] : [s.n.], 2009. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=018685872&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Full textSchoonmaker, Benjamin L. "Clean Indices of Common Rings." BYU ScholarsArchive, 2018. https://scholarsarchive.byu.edu/etd/7027.
Full textGahramanov, Ilmar. "Superconformal indices, dualities and integrability." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät, 2016. http://dx.doi.org/10.18452/17568.
Full textIn this thesis we discuss exact, non-perturbative results achieved using superconformal index technique in supersymmetric gauge theories with four supercharges (which is N = 1 supersymmetry in four dimensions and N = 2 supersymmetry in three). We use the superconformal index technique to test several duality conjectures for supersymmetric gauge theories. We perform tests of three-dimensional mirror symmetry and Seiberg-like dualities. The purpose of this thesis is to present recent progress in non-perturbative supersymmetric gauge theories in relation to mathematical physics. In particular, we discuss some interesting integral identities satisfied by basic and elliptic hypergeometric functions and their relation to supersymmetric dualities in three and four dimensions. Methods of exact computations in supersymmetric theories are also applicable to integrable statistical models, which we discuss in the last chapter of the thesis.
Heaver, Becky. "Psychophysiological indices of recognition memory." Thesis, University of Sussex, 2012. http://sro.sussex.ac.uk/id/eprint/39455/.
Full textRose, Philip. "Indices of fatty acid metabolism." Thesis, Sheffield Hallam University, 1992. http://shura.shu.ac.uk/20296/.
Full textGutiérrez, Hernández Julián Eli. "Drought Indices in Panama Canal." Master's thesis, Česká zemědělská univerzita v Praze, 2015. http://www.nusl.cz/ntk/nusl-258961.
Full textMermoz, Vincent. "Les indices en procédure pénale." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS094/document.
Full textOnce taking the form of a "sign of divinity" in the trial by ordeal, the clue would henceforth designate any "event, object or trace" that might forge the judge's conviction. The characteristics of the clue can thus be recognized by its ability to make the desired result possible. In this sense, the clue cannot – today as in the past – directly indicate guilt, although it has always been able to allow for the presumption that the prohibited fact is imputable to suspects. The effects of the clue have always been sought after, without anyone ever being able to explain them. The clue makes possible, has specific power and fits perfectly into the dialectical reasoning inherent in the legal field.Lawyers use clue-based presumptions to compensate for the deficiencies inherent in criminal evidence. Undeniably, the clue occupies a central place in the probationary process. Nevertheless, a finding of deficiency is inevitable: the reasons why the clue produces this effect, which is so characteristic and therefore so common, are never explained. Undoubtedly too prosaic, the clue has vanished into the background of criminal evidence that has become preponderant because of the seriousness of the legal consequences it justifies. A sharper look this time would nevertheless have foreshadowed the universal importance of such a notion: since time immemorial, the clue has been the foundation of proof. As the foundations of a fragmented reality that the justice system wishes to reconstruct, the clues mark out the procedural path until evidence is obtained. The various phases of criminal proceedings are organised according to the rhythm of the interpreted clues, as much as they forge a conviction about the conduct of the prohibited acts. The intimate conviction in fact anchors the interpretation of the clue at the heart of the criminal evidence and, with it, the perfectibility of a human construction at the centre of criminal procedure
Oladele, Oluwatosin Seun. "Low volatility alternative equity indices." Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/15691.
Full textShorrer, Ran I. "Essays on Indices and Matching." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17467351.
Full textBusiness Economics