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1

Betretdinova, Inessa, Olga Kurgaeva, and Shushanik Kazaryan. "Innovations in Teaching Business Letter Writing at Nonlinguistic Universities: Individually Differentiated Approach." ARPHA Proceedings 4 (May 31, 2021): 114–26. https://doi.org/10.3897/ap.e4.e0114.

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In the modern world the ability to perform professional interaction and conduct proper business correspondence is an integral part of successful commercial activities. The scope of knowledge necessary for efficient spoken and written communication is the basis of productive cooperation with foreign partners for specialists and experts in any field. This knowledge is to provide the increasing demand for such professionals as a current trend in the labour market. In this light, teaching business letter writing as a product of foreign language learning to students at nonlinguistic universities pr
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Rudenchenko, Alla. "INDIVIDUALLY-DIFFERENTIATED APPROACH TO PERSONAL DEVELOPMENT STUDENTS IN THE PROCESS OF ETNODYZAYNERSKOYI." Aesthetics and Ethics of Pedagogical Action, no. 13 (March 9, 2016): 140–51. http://dx.doi.org/10.33989/2226-4051.2016.13.171552.

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The article analyzes the need to introduce based on humanistic principles, innovation, personality-oriented educational model that would reflect the features of modern social and cultural space. Organization of scientific and educational process in higher educational institutions of art should be based on modern developments in the field of art education and art pedagogy, active use of the traditions of folk culture. The use of multiple intelligence theory of American psychologist Howard Gardner, will allow to increase the quality level of education, strengthen the relationship with the educat
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Krasheninnikova, Natalia A., Valentina V. Voroshilova, Olga S. Polunina, Natalia V. Osipova, Nikolay N. Kosarenko, and Jhanna I. Aytuganova. "The formation of language competence in the system of the speech generalization semantics among students." LAPLAGE EM REVISTA 7, no. 3B (2021): 258–67. http://dx.doi.org/10.24115/s2446-6220202173b1544p.258-267.

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The article aims to study the specificities of an individually differentiated approach in the formation of speech generalization semantics and communicative competence in older preschool children. The main approach to the study of this problem is the analysis of theoretical and methodological approaches in the study of an individually differentiated approach to the linguistic competence of preschool children, which allows us to identify the most effective ones. The article focuses on the concepts of individualization and differentiation in the development of the semantic aspect of speech and c
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Lavrienko, Tatiana V., and Tatiana V. Pen. "Individually-differentiated approach to the organization of the educational process for disabled people." Journal of Siberian Federal University. Humanities & Social Sciences 10, no. 2 (2017): 189–94. http://dx.doi.org/10.17516/1997-1370-0019.

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5

Novikova, Galina. "Organization of Pedagogical Assistance and Support for Younger Schoolchildren with Different Rates of Mental Development." Primary Education 10, no. 4 (2022): 40–44. http://dx.doi.org/10.12737/1998-0728-2022-10-4-40-44.

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The article is devoted to the problems of organizing individually differentiated work with younger students who experience difficulties in learning within the framework of inclusive education. The main indicators of children with the risks of mental retardation, which prevent their successful co-education with ordinary peers in the general class of a mass primary school, are characterized. The necessary conditions for the organization of pedagogical assistance and the features of an individually differentiated approach to children with different rates of mental development are considered in de
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Mandal, Paulami, Debojyoti De, Dong Uk Im, Sung Hee Um та Kyeong Kyu Kim. "Exosome-Mediated Differentiation of Mouse Embryonic Fibroblasts and Exocrine Cells into β-Like Cells and the Identification of Key miRNAs for Differentiation". Biomedicines 8, № 11 (2020): 485. http://dx.doi.org/10.3390/biomedicines8110485.

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Diabetes is a concerning health malady worldwide. Islet or pancreas transplantation is the only long-term treatment available; however, the scarcity of transplantable tissues hampers this approach. Therefore, new cell sources and differentiation approaches are required. Apart from the genetic- and small molecule-based approaches, exosomes could induce cellular differentiation by means of their cargo, including miRNA. We developed a chemical-based protocol to differentiate mouse embryonic fibroblasts (MEFs) into β-like cells and employed mouse insulinoma (MIN6)-derived exosomes in the presence
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Fuerman, Ross D. "Audit quality examined one large CPA firm at a time: mid-1990’s empirical evidence of a precursor of Arthur Andersen’s collapse." Corporate Ownership and Control 2, no. 1 (2004): 137–48. http://dx.doi.org/10.22495/cocv2i1p11.

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The largest CPA firms have been regarded as quality-differentiated auditors. This has been a prominent assumption of empirical research in accounting and auditing. Yet, prior research has only tested whether the largest CPA firms, in the aggregate, are quality-differentiated auditors. This paper contributes to the audit quality literature by individually examining each of the largest CPA firms. This new approach is timely, given the questions that have been raised concerning Arthur Andersen.
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Nikolaevna, Menshikova Anastasia. "Development of professional competencies of future designers based on an individually differentiated approach in professional design education." Vestnik of Kostroma State University. Series: Pedagogy. Psychology. Sociokinetics 29, no. 1 (2023): 122–31. http://dx.doi.org/10.34216/2073-1426-2023-29-1-122-131.

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The article deals with the problem of diagnostics and development of professional competences of future designers based on an individually differentiated approach. The author examines the specifics of the professional and creative competences of a modern designer, the prerequisites and conditions for their formation in the process of professional education. Professional creative competences are considered as a cluster of competencies that reflect the willingness of a future designer to perform productive professional activities, as an ability for personal and professional self-development by i
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Nikitina, E. "The Use of Creative Works of Younger Schoolchildren to Improve the Success of Their Educational Activities." Primary Education 10, no. 1 (2022): 39–42. http://dx.doi.org/10.12737/1998-0728-2022-10-1-39-42.

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The article proposes for consideration the problem of using creative works as an effective way to implement an individually differentiated approach in teaching successful younger schoolchildren. The author relies on the idea that difficulties in the learning process can occur in children who demonstrate different levels of educational activity, in particular, also in excellent schoolchildren and "good schoolchildren", therefore, providing them with different levels of creative tasks allows for the successful prospective intellectual and creative development of such schoolchildren. Examples of
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10

Golovyashkina, Marina Aleksandrovna. "ON THE PROBLEM OF THE INDIVIDUALLY-DIFFERENTIATED APPROACH IN TEACHING A FOREIGN LANGUAGE AT THE NON-LINGUISTIC UNIVERSITY." Philological Sciences. Issues of Theory and Practice, no. 2-2 (February 2018): 405–8. http://dx.doi.org/10.30853/filnauki.2018-2-2.48.

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11

Sodikova, Yulduz Furqatovna. "EXTRA-CURRICULUM INDEPENDENT WORK AND ITS ROLE OF LEARNING ACTIVITIES OF LANGUAGE STUDENTS." Academic Research Journal 2, no. 1 (2023): 103–10. https://doi.org/10.5281/zenodo.7558449.

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A systematic approach to the organization and management of independent work of students at the university is considered. The importance of independent work of students in the educational activity of students as a condition and way of intensifying their cognitive activity is substantiated. Pedagogical conditions are proposed that contribute to the effective organization and management of independent work of students at the university and the implementation of an individually differentiated approach to teaching students in higher education. Independent work of students is considered as a specia
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12

Filina, Irina, Vladimir Dresvyankin, Olga Pryanishnikova, and Elena Chernysheva. "Individually differentiated approach to the educational process for the ski preparation of the students of the physical culture profile university." Uchenye zapiski universiteta imeni P.F. Lesgafta, no. 103 (September 2013): 182–86. http://dx.doi.org/10.5930/issn.1994-4683.2013.09.103.p182-186.

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13

Kozyreva, Natalia V. "Formation of motivation for choosing a profession for students of educational organizations in the context of an individually differentiated approach." Pedagogical Perspective, no. 2 (2021): 17–22. http://dx.doi.org/10.55523/27822559_2021_2_17.

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14

Noviantari, Ika, and Rica Rica. "Differentiated Learning Approaches in Introvert and Extrovert Students from The Aspect of Personality Type in Vocational School Students." Journal of Mathematics and Applied Statistics 1, no. 2 (2023): 63–72. http://dx.doi.org/10.35914/mathstat.v1i2.92.

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The main objective of this research is to obtain data related to differentiated learning for introverted and extroverted students in vocational education/Vocational High Schools (SMK). The research carried out is a type of qualitative research with a case study approach. The data collection techniques used in this research were interviews and documentation. The questions will develop and be more open but still have the same focus. The interviews conducted in this research included interviews with 4 students as subjects chosen by students in class X of SMK Negeri 3 Tarakan. There were 4 partici
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15

Kostyuchenko, V. F., A. A. Skidan, and E. P. Vrublevskiy. "The individual differentiated training design of health-promoting shaping with mature age women." Pedagogics, psychology, medical-biological problems of physical training and sports 22, no. 6 (2018): 295–300. http://dx.doi.org/10.15561/18189172.2018.0603.

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Purpose: theoretical justification, development, and approbation of individual differentiated training design of health-promoting shaping with mature age women. Material: women aged from 21-55 years (n=86) participated in the research. It was determined the initial level of their morphofunctional state and physical fitness (it was considered phases of an individual ovarian menstrual cycle). It was revealed criteria of the individual differentiated approach to the design of health-promoting shaping training (it was considered biorhythms of the female body). It was realized the nine-months macro
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16

Vinogradova, Natalya. "Goals and Directions of Updating the Federal State Educational Standard of Primary General Education." Primary Education 10, no. 4 (2022): 3–5. http://dx.doi.org/10.12737/1998-0728-2022-10-4-3-5.

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The article discusses the problem of implementing the priority goals of the updated version of the Federal State Educational Standard for Primary General Education: providing a unified educational space, developing in primary school children systemic knowledge about Russia's place in the world, preserving and developing cultural diversity and the linguistic heritage of the peoples of the Russian Federation, solving the most important task of personal student development. The conditions under which the successful education of younger schoolchildren is ensured are characterized: the use of an in
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17

Усманова, Евгения, and Елена Никитина. "Individually differentiated approach to provision of preparation process of young footballers on the basis of account for their individual mental peculiarities." Theory and Methods of Physical Education and Sports, no. 4 (October 23, 2014): 18–22. http://dx.doi.org/10.32652/tmfvs.2014.4.18-22.

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18

Ibodzoda, H. I., M. A. Oripov, R. R. Rofiev, and T. Sh Ikromi. "A differentiated approach to the treatment of infected hydatid cysts of the lungs in children." Health care of Tajikistan, no. 4 (February 7, 2025): 37–46. https://doi.org/10.52888/0514-2515-2024-363-4-37-46.

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Aim of the study. To optimize the diagnosis, treatment, and prevention of postoperative complications in children with infected hydatid cysts of the lungs complicated by rupture into the bronchus or pleural cavity.Materials and methods. The study analyzed the results of diagnosis and treatment of infected hydatid cysts of the lungs that had ruptured into the bronchus and pleural cavity in 120 children. Depending on the size and volume of the hydatid cysts, the following groups were diagnosed: small – 22 (18.3%), medium – 56 (46.7%), large – 24 (20.0%), and giant – 18 (15.0%). Rupture into the
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19

Shushardzhan, Sergey. "VOCAL THERAPY METHOD IN HEALING OF CHRONIC RESPIRATORY DISEASES." Medicine and Art 2, no. 1 (2024): 7–24. http://dx.doi.org/10.60042/2949-2165-2024-2-1-7-24.

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This article is devoted to the prospects for the use of singing as an art in the treatment and rehabilitation of chronic respiratory diseases. A review of literature data is presented, demonstrating the effectiveness of this approach, shown in numerous clinical studies. At the same time, the methodological features of a more in-depth and differentiated therapeutic and prophylactic methods are presented. It is the method of Vocal Therapy, based on the principles of academic singing and developed in Russia in the early nineties of the last century. It is carried out both in groups and individual
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20

Artyuhova, Irina. "Differentiation and Individualization of Primary School Education Abroad." Primary Education 9, no. 3 (2021): 41–48. http://dx.doi.org/10.12737/1998-0728-2021-9-3-41-48.

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The article presents the main results of a critical analysis of the global trend, which is aimed at implementing an individual approach to teaching younger students. The characteristics of the features of primary education in the leading countries, whose primary school students demonstrate a high level of educational achievements in the course of international monitoring studies and occupy corresponding places (Finland and Singapore) are given. Attention is paid to the approach to selection, current forms of work and encouragement of especially gifted children in the US primary education syste
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21

Havrylova, Natalia, and Larysa Platash. "Method of articulatory motility forming in children with erased form of dysarthria (personally priented approach)." Actual problems of the correctional education (pedagogical sciences) 20 (December 30, 2022): 14–34. http://dx.doi.org/10.32626/2413-2578.2022-20.14-34.

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In the current conditions of introducing inclusion into the education system, individually oriented education is the leading direction that determines its further development. In this context, the formation of individual programs that ensure the development of children's speech is one of the priority areas of research. The article, based on the analysis of scientific and theoretical sources, defines the differentiated differences between the concepts of "dysarthria" and "erased form of dysarthria," characterizes the main approaches to the study of this speech disorder, classification, diagnost
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22

Dong, Xiaoyun, Christopher Korch, and Judy L. Meinkoth. "Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells." Endocrine-Related Cancer 18, no. 3 (2011): 301–10. http://dx.doi.org/10.1530/erc-10-0320.

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Increases in Rap activity have been associated with tumor progression. Although activating mutations in Rap have not been described, downregulation of Rap1GAP is frequent in human tumors including thyroid carcinomas. In this study, we explored whether endogenous Rap1GAP expression could be restored to thyroid tumor cells. The effects of deacetylase inhibitors and a demethylating agent, individually and in combination, were examined in four differentiated and six anaplastic thyroid carcinoma (ATC) cell lines. Treatment with the structurally distinct histone deacetylase (HDAC) inhibitors, sodium
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23

Patchell, Jerry. "Evolution of Collective Action in a Ski Resort Facing Declining Domestic Demand and Inbound Opportunity: Hakuba's Dynamic Downsizing." Environment and Planning A: Economy and Space 46, no. 11 (2014): 2752–68. http://dx.doi.org/10.1068/a130062p.

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In Japan's ski boom of 1960–80 Hakuba's subsistence farmers collectively transformed adjacent mountain slopes into ski areas and built new incomes by individually offering accommodation. Since the domestic market went bust, they have reorganized collective and individual efforts to create a destination resort attractive to inbound tourists. A differentiated common pool resources approach, using concepts from evolutionary economy geography, is utilized to evaluate their success in this endeavor. This structure evolved path dependencies that inhibit coordination of ski areas, generate some divis
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Siva, PR Muppala, and Chandramohan Balasubramanyam. "Development of a Learning Model for Large Class Cohorts to Strengthen Learning Outcomes of Students Based on Differentiated Instruction." Education Quarterly Reviews 4, no. 1 (2021): 168–72. https://doi.org/10.31014/aior.1993.04.01.184.

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We propose a new approach to classroom learning based on sequential numeral-division. It builds on the concept of trichotomy – division of students based on creamy-level, middle-level and weaker-level students -- proposed by the present authors. A sequenced series of formative assessments can map student progress and achievement, particularly in the case of weaker students. The idea behind the development of this model is to study if weak students perform better on critical-thinking tests in a collaborative learning setting rather than when they study individually. We propose a mathemati
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Zaremba, V. R., and O. A. Danylov. "Surgical approach to treatment of asymmetric pectus excavatum in children." Paediatric Surgery. Ukraine, no. 1(74) (March 30, 2022): 27–33. http://dx.doi.org/10.15574/ps.2022.74.27.

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Objective. To improve the outcomes in patients with asymmetric pectus excavatum (APE) by developing and implementing our own differentiated modified Nuss procedure to correct different variants of this deformity; to analyse the treatment outcomes. Materials and methods. An original modified Nuss procedure to correct the following pectus excavatum (PE) types is described: asymmetric eccentric focal (ІІА1 according to Park) type; asymmetric eccentric broad-flat (Park ІІА2) type; asymmetric eccentric long canal (the Grand Canyon type or Park IIA3) type; asymmetric unbalanced (Park IIB) type; asym
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Belaya, N. A., and E. G. Rechitskaya. "FORMATION OF COMMUNICATIVE COMPETENCE PRESCHOOL CHILDREN WITH HEARING LOSS (PROBLEM STATEMENT)." EurasianUnionScientists 8, no. 4(73) (2020): 8–11. http://dx.doi.org/10.31618/esu.2413-9335.2020.8.73.701.

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The article deals with the problem of formation of communicative competence in children with hearing impairment as the basis of their social and personal development. It is shown that a significant component of communicative competence is speech communication, which in turn is represented by such components as ideas about communication, communication skills, speech tools, natural gestures, and communicative qualities of the individual. The article reveals the developing possibilities of correctional and pedagogical work on the basis of an individually differentiated approach to the formation o
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Usca, Svetlana, and Aija Vindece. "ACTIVITY OF YOUNG PEOPLE WITH DISABILITIES IN THE DIGITAL ENVIRONMENT." Education Reform: Education Content Research and Implementation Problems 1 (June 16, 2020): 33. http://dx.doi.org/10.17770/er2020.1.5195.

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Young people with disabilities are often socially inactive because their participation in social and economic processes is limited. In order to reduce this, digital technologies are important, the use of which allows any individual to engage in various types of activities (educational, cultural, economic, etc.).Objective of the paper: to analyze the results of exploratory research on the activity of young people with disabilities in the digital environment. Methods: questionnaire, focus discussion.The results suggest that support and education measures require a differentiated approach, in whi
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Costanzo, Matteo, Eleonora Galosi, Maria Ilenia De Bartolo, et al. "Evaluating the Diagnostic Potential of Combined Salivary and Skin Biomarkers in Parkinson’s Disease." International Journal of Molecular Sciences 25, no. 9 (2024): 4823. http://dx.doi.org/10.3390/ijms25094823.

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Oligomeric alpha-synuclein (α-syn) in saliva and phosphorylated α-syn deposits in the skin have emerged as promising diagnostic biomarkers for Parkinson’s disease (PD). This study aimed to assess and compare the diagnostic value of these biomarkers in discriminating between 38 PD patients and 24 healthy subjects (HSs) using easily accessible biological samples. Additionally, the study sought to determine the diagnostic potential of combining these biomarkers and to explore their correlations with clinical features. Salivary oligomeric α-syn levels were quantified using competitive ELISA, while
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Stine, Jared S., Nicolas Aziere, Bryan J. Harper, and Stacey L. Harper. "A Novel Approach for Identifying Nanoplastics by Assessing Deformation Behavior with Scanning Electron Microscopy." Micromachines 14, no. 10 (2023): 1903. http://dx.doi.org/10.3390/mi14101903.

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As plastic production continues to increase globally, plastic waste accumulates and degrades into smaller plastic particles. Through chemical and biological processes, nanoscale plastic particles (nanoplastics) are formed and are expected to exist in quantities of several orders of magnitude greater than those found for microplastics. Due to their small size and low mass, nanoplastics remain challenging to detect in the environment using most standard analytical methods. The goal of this research is to adapt existing tools to address the analytical challenges posed by the identification of nan
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Dilmaghani, Maryam. "Religiosity, gender, and wage: the differentiated impact of private prayer in Canada." International Journal of Social Economics 42, no. 10 (2015): 888–905. http://dx.doi.org/10.1108/ijse-11-2013-0261.

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Purpose – Does religiosity impact wages differently for males and females? Does the impact on wage of different dimensions of religiosity, namely the importance of religion, the frequency of religious practice with others and individually, differ for men and women? The paper aims to discuss these issues. Design/methodology/approach – Using the Canadian Ethnic Diversity Survey, made public in 2004, this paper investigates whether there are evidences for a gender difference in the impact of religiosity on wage. A Mincerean wage regression is estimated using both multiple linear regression and He
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Kaminskyi, V. V., K. V. Chaika, Yu V. Lavreniuk, O. O. Diadyk, Yu I. Beketova та O. P. Baryshnikova. "Comparative efficacy оf non-surgical correction of early-onset genital prolapse based on differentiated approach". Reproductive health of woman 3 (3 травня 2021): 75–80. http://dx.doi.org/10.30841/2708-8731.3.2021.234254.

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The paper presents the results of the comparative efficacy of non-surgical correction of early-onset genital prolapse (GP) in women of perimenopausal and menopausal age using differentiated approach. The objective: to study morphological traits of the vaginal walls and to compare the effectiveness of non-surgical techniques of GP correction. Materials and methods. The study involved 120 patients with early-onset GP. The treatment group (Group 1) consisted of 90 women with GP who were divided into three subgroups depending on the non-surgical correction technique chosen (utility model patent No
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Safronova, E. M., and T. A. Bondarenko. "Educational activities in the conditions of educational inclusion: phenomenon, specifics, advantages." Psychological-Educational Studies 17, no. 2 (2025): 103–18. https://doi.org/10.17759/psyedu.2025170207.

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<p><strong>Context and relevance</strong>. Since inclusive education is a legal requirement in the Russian Federation, the issues of organizing education in non-standard conditions for teachers and parents need special research and reflection. At the same time, pedagogical science, in particular, the theory of education, the concept of inclusive education, faces a number of questions: Who is the subject of education in the context of inclusion? Is there an additional educational resource in inclusive education? <strong>Objective.</strong> Clarification of the phen
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Syafi', Moh Agus Syairofi. "Implementation of Modified Curriculum at Elementary School Muhammadiyah 2 Sidoarjo." JISIP (Jurnal Ilmu Sosial dan Pendidikan) 9, no. 3 (2025): 1598. https://doi.org/10.58258/jisip.v9i3.9070.

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This study aims to examine the implementation of the Modified Curriculum at SD Muhammadiyah 2 Sidoarjo. A qualitative descriptive approach was used, with data collected through interviews, observations, and documentation. The findings reveal that lesson planning, implementation, evaluation, and the challenges encountered are integral components of the curriculum implementation process. In the planning phase, an initial needs assessment is conducted, followed by the development of a syllabus that includes setting learning objectives and preparing self-instructional modules. During the implement
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34

Zobkov, Dmitry A. "Hockey player anthropometric data as the variability basis of the game adaptation method in amateur student teams." Tambov University Review. Series: Humanities, no. 3 (2023): 657–64. http://dx.doi.org/10.20310/1810-0201-2023-28-3-657-664.

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Importance. The conditions of planning a component of sports training aimed at the game adaptation of students with special anthropometric indicators and engaged in hockey in non-professional student teams are considered. The necessary conditions for structuring include: the characteristics of the necessary motor game actions and their adequacy when performed by players with appropriate anthropometric parameters; improving the vestibular apparatus while ensuring static and dynamic equilibrium in gaming activities, as well as correcting the time parameters of motor actions that ensure the effec
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35

V.V., Kaminskyi, Chaika K.V., Lavreniuk Yu.V., Diadyk O.O., Beketova Yu.I. та Baryshnikova O.P. "Comparative efficacy оf non-surgical correction of early-onset genital prolapse based on differentiated approach". Reproductive health of woman 3 (3 березня 2021): 75–80. https://doi.org/10.30841/2708-8731.3.2021.234254.

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The paper presents the results of the comparative efficacy of non-surgical correction of early-onset genital prolapse (GP) in women of perimenopausal and menopausal age using differentiated approach. <strong>The objective:</strong>&nbsp;to study morphological traits of the vaginal walls and to compare the effectiveness of non-surgical techniques of GP correction. <strong>Materials and methods.</strong>&nbsp;The study involved 120 patients with early-onset GP. The treatment group (Group 1) consisted of 90 women with GP who were divided into three subgroups depending on the non-surgical correcti
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36

Pozdnyakov, V. M., and K. A. Khrushkova. "Methodological and Theoretical Guidelines for the Study of Learned Helplessness in Convicts with Long Terms of Serving Criminal Sentences." Psychology and Law 12, no. 3 (2022): 151–67. http://dx.doi.org/10.17759/psylaw.2022120313.

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The increase in the number of convicts with long sentences in domestic correctional colonies over the past decade, and at the same time the expansion of persons with psychosocial immaturity among them, contributes to the acquisition by this category of special contingent with prolonged isolation of learned helplessness. Based on the analysis of foreign and domestic publications, the causes and features of the development of this destruction in different categories of convicts as a psychological state and personal education are revealed. In accordance with the requirement of the Concept for the
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Sokolova, M. G., E. V. Lopatina, S. V. Lobzin, A. V. Gavrichenko, A. A. Zuev, and O. S. Roshchina. "Biotechnological approach for substantiation of differentiated application of neuroprotective therapy in patients with hereditary neuromuscular diseases." Medical alphabet, no. 22 (October 20, 2020): 48–51. http://dx.doi.org/10.33667/2078-5631-2020-22-48-51.

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Hereditary neuromuscular diseases are a group of genetic diseases characterized by an onset of the disease in most cases in childhood, having a steadily progressive course of the pathological process, leading to more rapid disability of patients and having a high mortality rate at the age of 18–20 years.Objective. To study a condition of the intra-organ structure in patients with hereditary muscular atrophy and muscular dystrophy using testing of nerve tissue in the organotypic environment in order to justify the prescription of symptomatic neuroprotective therapy.Materials and methods. Ninety
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Shkarin, V. V., Yu A. Makedonova, S. V. Dyachenko, I. V. Venskel, L. M. Gavrikova, and L. A. Devyatchenko. "Development and justification of a hardware and software complex for the diagnosis of diseases of the oral mucosa." Medical alphabet 1, no. 1 (2023): 39–43. http://dx.doi.org/10.33667/2078-5631-2023-1-39-43.

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Relevance. Currently, a significant increase in diseases of the oral mucosa, manifested by inflammatory and destructive lesions, has been revealed. To determine the correct tactics for the treatment of inflammatory and destructive lesions in lichen planus, it is necessary to comprehensively assess the situation in the oral cavity, taking into account planimetry data, the size of the inflammatory background, the presence of exudate, the severity of pain syndrome, and also include criteria for the stages of the lesion in the evaluation system, which requires a personalized and differentiated app
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Lv, J. G., S. Liu, J. M. Feng, Y. Liu, S. D. Zhou, and R. Chen. "Effective identification of paints pigments in hit-and-run cases with confocal Raman microscope." Pigment & Resin Technology 45, no. 4 (2016): 294–300. http://dx.doi.org/10.1108/prt-05-2015-0044.

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Purpose The purpose of this paper is to identify different automotive coatings using Confocal Raman microscope which could hardly be differentiated with Fourier transform infrared microscope (FTIR). Design/methodology/approach Raman spectroscopy was used to provide extra vibration information to infrared spectroscopy. Paints preparation was not necessary, and only 30 s was needed for each sample in an optimised method. Paints were first analysed by FTIR and then compared with Raman microscope. Findings Raman microscope was used to address the lack of ability of FTIR in discriminating four grou
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Egerhag, Helén, Linda Fälth, Camilla Nilvius, Heidi Selenius, and Idor Svensson. "Promoting decoding among young students with Swedish as a first and second language within a response to intervention model." Journal of Childhood, Education & Society 4, no. 2 (2023): 176–92. http://dx.doi.org/10.37291/2717638x.202342282.

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Many young students with Swedish as their second language need support to acquire reading ability. There is a need for evidence-based reading instruction in early reading education for students with Swedish as their first or second language. Therefore, the current study investigated whether early reading education based on a Response to Intervention (RTI) model with a focus on decoding skills can promote reading ability among young students with Swedish as their first or second language. In Grades 1 and 2, 113 students with Swedish as a first and Swedish as a second language were followed. App
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Ikawa, Masahito. "CRISPR/Cas9 Mediated KO Studies Identified Essential Genes for Fertilization and Oocyte Activation." Fertility & Reproduction 05, no. 04 (2023): 295. http://dx.doi.org/10.1142/s2661318223741097.

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CRISPR/Cas9 system has opened a new era for reverse genetics. Taking advantage of the CRISPR/Cas9-mediated approaches, our laboratory has knocked out 421 male reproductive organ-specific genes and analysed their phenotypes in vivo. Surprisingly, even with the highly testis-specific genes (TPM&gt;10 and 10 times higher expression than any other non-reproductive tissues), only one-third is individually essential for male fertility (37/120=30.8%), suggesting that the tissue-specific expression does not necessarily mean essential for physiological functions ( 1 ). Nevertheless, this KO screening a
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Aligaeva, Nigar N. "Experience in the implementation of the programme of psychological correction of emotional states of disabled convicts." Vestnik of Kostroma State University. Series: Pedagogy. Psychology. Sociokinetics 27, no. 3 (2021): 224–33. http://dx.doi.org/10.34216/2073-1426-2021-27-3-224-233.

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The article presents the results of the verification of the programme of psychological correction of the emotional states of disabled convicts, developed on the basis of a “time” approach and including three main blocks “Past”, “Present” and “Future”. The study involved 68 convicts serving sentences in a maximum security correctional colony (20 people with a disability group and 48 people without a disability). Evaluation of emotional states was carried out using the following methods – TOBOL (Lyudvig Vasserman, Aleksandr Vuks, Boris Iovlev, El'vira Karpova), State-Trate Anxiety Inventory by C
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Mariappanadar, Sugumar. "The impact of dissonance in schema based leadership perceptions on employee engagement." Personnel Review 47, no. 7 (2018): 1309–29. http://dx.doi.org/10.1108/pr-03-2017-0081.

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Purpose The purpose of this paper is to explore the possible consequences of the intra-individual level-based perceptions of participative, supportive and instrumental leadership styles and the dissonance factors of leadership styles perceptions on employee engagement using the information-processing and connectionist perspectives of leadership perceptions. Design/methodology/approach Hypotheses relating to direct and moderated effects of perceptions of leadership styles on employee engagement were tested using a two-stage intra-individual level study (n=172 in each stage). Hierarchical regres
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Akongyam, Merri, Fofie Douglas, Maxwell Kontor Owusu, William De-Heer, and Agbenyefia Xorsenyo. "Pedagogical competencies of teachers applied to teaching learners with hearing difficulties." American Journal of Education and Learning 8, no. 2 (2023): 138–51. http://dx.doi.org/10.55284/ajel.v8i2.958.

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Teachers need to possess appropriate pedagogical competencies to be successful in addressing the special needs of students in the classroom so as to ensure their accomplishment in education. This study investigated teachers’ pedagogical competencies applied to teaching learners with hearing difficulties in the Sekyere South District of Ghana. This study adopted the constructivist paradigm using the qualitative approach. The case study design was employed. In this case study, 16 teachers were purposively sampled, and data were collected from them using a self-constructed interview guide. The in
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Jiang, Weiwei, Yafeng Zhan, and Xiaolong Xiao. "Multi-Domain Network Slicing in Satellite–Terrestrial Integrated Networks: A Multi-Sided Ascending-Price Auction Approach." Aerospace 10, no. 10 (2023): 830. http://dx.doi.org/10.3390/aerospace10100830.

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With the growing demand for massive access and data transmission requests, terrestrial communication systems are inefficient in providing satisfactory services. Compared with terrestrial communication networks, satellite communication networks have the advantages of wide coverage and support for massive access services. Satellite–terrestrial integrated networks are indispensable parts of future B5G/6G networks. Challenges arise for implementing and operating a successful satellite–terrestrial integrated network, including differentiated user requirements, infrastructure compatibility, limited
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Qafarov, A. A. "Methodology of teaching future teachers of informatics interactive network technologies." Professional education in the modern world 14, no. 1 (2024): 161–69. http://dx.doi.org/10.20913/2618-7515-2024-1-19.

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Introduction. In article are stated progressive, vanguard to methodology of teaching of modern network technologies, including various electronic tutorials and the differentiated modular approach are considered.Purpose setting. The purpose of the article is to substantiate the need to develop a special methodology for teaching modern network technologies using electronic learning tools.Methodology and methods of the study. Use of the modular approach in the course of preparation of the future teachers of computer science allows to concern individually each pupil, in details to reveal level of
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Panganiban, Ronaldo Paolo, Marina Chulkina, Christina McAninch, et al. "TARGETING MYD88-JAK2 SIGNALING IN ABERRANTLY DIFFERENTIATED MESENCHYMAL PROGENITORS IN ULCERATIVE COLITIS." Inflammatory Bowel Diseases 31, Supplement_1 (2025): S5—S6. https://doi.org/10.1093/ibd/izae282.015.

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Abstract INTRODUCTION Three novel therapies have shown promise in managing moderate-to-severe ulcerative colitis (UC): fecal microbiota transplantation (FMT), mesenchymal stem cell (MSC) therapy, and targeting the JAK/STAT signaling pathway. Individually, these treatment approaches face issues with either safety concerns or limited efficacy due to disease relapses. Yet, the development of better strategies is hampered by limited knowledge about the cellular mechanisms driving chronic inflammation and disease relapse in UC. In UC, the number of aberrantly differentiated tissue resident MSCs in
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Kesapragada, Manasa, Yao-Hui Sun, Kan Zhu, et al. "A data-driven approach to establishing cell motility patterns as predictors of macrophage subtypes and their relation to cell morphology." PLOS ONE 19, no. 12 (2024): e0315023. https://doi.org/10.1371/journal.pone.0315023.

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The motility of macrophages in response to microenvironment stimuli is a hallmark of innate immunity, where macrophages play pro-inflammatory or pro-reparatory roles depending on their activation status during wound healing. Cell size and shape have been informative in defining macrophage subtypes. Studies show pro and anti-inflammatory macrophages exhibit distinct migratory behaviors, in vitro, in 3D and in vivo but this link has not been rigorously studied. We apply both morphology and motility-based image processing approaches to analyze live cell images consisting of macrophage phenotypes.
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Golovin, A. V., A. A. Troshina, V. R. Mantsova, and A. V. Proshko. "An integrated approach to the surgical treatment of cataracts in patients with vascular leukomas at various stages of keratoprosthesis implantation." Fyodorov journal of ophthalmic surgery 144, no. 2 (2025): 16–28. https://doi.org/10.25276/0235-4160-2025-2-16-28.

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Purpose. To evaluate the differentiated approach to surgical treatment of patients with vascular leukomas of various etiologies and lens opacification, including cataract extraction at various stages of keratoprosthesis implantation. Material and methods. A comprehensive analysis of complex optical-reconstructive treatment of 30 patients (30 eyes) aged from 16 to 74 with vascular leukomas of various etiologies and lens opacification was carried out. All patients underwent multi-stage surgical treatment, including keratoprosthesis implantation and cataract extraction. The necessary steps and vo
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Bijlsma, Maarten F., Patrick Christian Strasser, Maximilian Christoph Schneider, and Norbert Thumfart. "A novel early cancer detection approach for pancreatic cancer." Journal of Clinical Oncology 42, no. 3_suppl (2024): 613. http://dx.doi.org/10.1200/jco.2024.42.3_suppl.613.

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613 Background: Pancreatic adenocarcinoma (PDAC) is commonly diagnosed at advanced stages, leading to high mortality rates. Earlier detection of PDAC is associated with improved long-term survival, but effective population-level screening is not available. There is therefore an urgent need to improve early detection of PDAC. Wholomics has developed a PDAC-specific proprietary early detection test, using cancer-specific molecular signatures in peripheral blood. Methods: We conducted a retrospective analysis of serum samples from the Amsterdam UMC Liquid Biopsy Center. Three cohorts were include
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