Academic literature on the topic 'Indole alkaloids; Substitution reactions'

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Journal articles on the topic "Indole alkaloids; Substitution reactions"

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Sariöz, Ö., та M. I. Abdullah. "Electrophilic substitution reactions of indole alkaloids with α,β-unsaturated carbonyl compounds in the presence of K10 montmorillonite". Russian Journal of Organic Chemistry 42, № 6 (2006): 879–82. http://dx.doi.org/10.1134/s107042800606011x.

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Nagaraju, Karre, and Dawei Ma. "Oxidative coupling strategies for the synthesis of indole alkaloids." Chemical Society Reviews 47, no. 21 (2018): 8018–29. http://dx.doi.org/10.1039/c8cs00305j.

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Partsvaniya, D. A., R. N. Akhvlediani, V. E. Zhigachev, E. N. Gordeev, L. N. Kuleshova, and N. N. Suvorov. "Indole derivatives. 129. Electrophilic-substitution reactions in 4,5-ethylenedioxyindole." Chemistry of Heterocyclic Compounds 23, no. 7 (1987): 755–57. http://dx.doi.org/10.1007/bf00475642.

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Somei, Masanori, Fumio Yamada, and Daisuke Shinmyo. "Nucleophilic Substitution Reactions on Indole Nucleus: Syntheses of 2-Substituted Indole-3-carboxaldehydes." HETEROCYCLES 38, no. 2 (1994): 273. http://dx.doi.org/10.3987/com-93-6599.

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Dittami, James P., and Halasya Ramanathan. "Intramolecular radical cyclization reactions. An approach to the indole alkaloids." Tetrahedron Letters 29, no. 1 (1988): 45–48. http://dx.doi.org/10.1016/0040-4039(88)80012-1.

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Blechert, Siegfried, Ruth Knier, Harald Schroers, and Thomas Wirth. "Domino Reactions - New Concepts in the Synthesis of Indole Alkaloids and Other Polycyclic Indole Derivatives." Synthesis 1995, no. 05 (1995): 592–604. http://dx.doi.org/10.1055/s-1995-3950.

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Song, Jin, Dian-Feng Chen, and Liu-Zhu Gong. "Recent progress in organocatalytic asymmetric total syntheses of complex indole alkaloids." National Science Review 4, no. 3 (2017): 381–96. http://dx.doi.org/10.1093/nsr/nwx028.

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Abstract Indole and its structural analogues have been frequently found in numerous alkaloids, pharmaceutical products and related materials. The enantioselective construction of these structures allows efficient total synthesis of optically pure indole alkaloids, and hence has received worldwide interest. In the past decade, asymmetric organocatalysis has been recognized as one of the most powerful strategies to create chiral molecules with high levels of stereoselectivity. In particular, organocatalytic asymmetric cascade reactions often occur with multiple bond-breaking and forming events s
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Ohno, Hiroaki, and Shinsuke Inuki. "Nonbiomimetic total synthesis of indole alkaloids using alkyne-based strategies." Organic & Biomolecular Chemistry 19, no. 16 (2021): 3551–68. http://dx.doi.org/10.1039/d0ob02577a.

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Significance of nonbiomimetic natural product synthesis and nonbiomimetic total syntheses of indole alkaloids based on the construction of core structures using alkyne reactions are summarized in this review.
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Liu, Yun-Lin, Guo-Shu Chen, and Xiao-Tong Lin. "3-(2-Isocyanoethyl)indole: A Versatile Reagent for Polycyclic Spiroindoline Synthesis." Synlett 31, no. 11 (2020): 1033–39. http://dx.doi.org/10.1055/s-0039-1690853.

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Polycyclic spiroindolines are the basic skeletons of large families of indole alkaloids that exhibit a broad spectrum of biological and pharmacological activities. The past seven years have seen impressive developments in the construction of polycyclic spiroindolines enabled by 3-(2-isocyanoethyl)indole-based cascade reactions. We herein give a brief summary on this evolution and highlight our contributions in this field.1 Introduction2 Cascade Reactions Involving Nitrilium Ion Intermediates3 Cascade Reactions Involving Ketenimine Intermediates4 Conclusion and Outlook
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Pritchett, Beau P., and Brian M. Stoltz. "Enantioselective palladium-catalyzed allylic alkylation reactions in the synthesis of Aspidosperma and structurally related monoterpene indole alkaloids." Natural Product Reports 35, no. 6 (2018): 559–74. http://dx.doi.org/10.1039/c7np00069c.

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Dissertations / Theses on the topic "Indole alkaloids; Substitution reactions"

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Aboutayab, Karim. "Novel methods for the synthesis of functionalised indoles." Thesis, University of Sussex, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262319.

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The work in this thesis describes investigations into the development of a tandem radicallDiels-Alder reaction strategy for the construction of indole alkaloids. The synthesis of a key precursor, 2-[(4-methylphenyl)sulfonyl]indole, was investigated and involved two main· strategies: functionalisation of the indole ring using lithiation procedures and assembling the indole as a key step (chapter 2). A method based on the former strategy was deemed to be the most practical and delivered the desired product in moderate yields (35 - 45%). The viability of the first step of the proposed tandem radi
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單慧媚 and Wai-mei Della Sin. "Addition reactions of 3H-indoles and their N-oxides." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1992. http://hub.hku.hk/bib/B31233193.

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Cao, Guo-an. "Study of Diels-Alder reactions in the syntheses of Yuehchukene analogues and optically active Yuehchukene /." [Hong Kong : University of Hong Kong], 1993. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13440032.

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Pavlakos, Ilias. "Studies of cyclisation reactions of highly substituted diketopiperazines : new access to prenylated indole alkaloids." Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3885/.

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The size of the prenylated indole alkaloid family sharing the unique bicyclo[2.2.2]diazaoctane core ring system has grown steadily over the last decades. Due to the complex structures, and in some cases the potent biological activity, these molecules have been adopted as challenging targets for several synthetic groups. Chapter One gives an introduction to these alkaloids, their origin, biological activity and biosynthetic studies. Our strategies to deliver 5,6- and 6,6-fused diketopiperazines (DKPs) and monoketopiperazines (MKPs) are discussed in Chapter Two. Radical cyclisation of a phenylse
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曹國安 and Guo-an Cao. "Study of Diels-Alder reactions in the syntheses of Yuehchukene analogues and optically active Yuehchukene." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1993. http://hub.hku.hk/bib/B31232942.

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Miller, Kenneth Aaron 1979. "(Rh(CO)₂Cl)₂-catalyzed allylic substitution reactions and domino sequences and application of the Pauson-Khand reaction to the synthesis of azabicyclic structures: total synthesis of (-)-alstonerine." Thesis, 2007. http://hdl.handle.net/2152/3495.

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Examination of the scope of the [Rh(CO)₂Cl]₂-catalyzed allylic substitution reaction as well as the development of a domino [Rh(CO)₂Cl]₂-catalyzed allylic alkylation/Pauson Khand reaction is described. A number of experiments were carried out in order to explore the novel regioselectivity in the [Rh(CO)₂Cl]₂-catalyzed allylic substitution reaction, and the [Rh(CO)₂Cl]₂-catalyzed allylic substitution reaction was found to give products resulting from attack of the nucleophile on the carbon bearing the leaving group in a highly regioselective fashion in most cases. Examination of allylic carb
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Books on the topic "Indole alkaloids; Substitution reactions"

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Mieczkowski, Józef Bogusław. Zastosowanie reakcji substytucji nukleofilowej do pełnych syntez wybranych alkaloidów i nowych układów heterocyklicznych. Wydawnictwa Uniwersytetu Warszawskiego, 1990.

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Book chapters on the topic "Indole alkaloids; Substitution reactions"

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Takayama, Hiromitsu, and Shin-Ichiro Sakai. "Chapter 11 Monoterpenoid Indole Alkaloid Syntheses Utilizing Biomimetic Reactions." In The Alkaloids: Chemistry and Biology. Elsevier, 1998. http://dx.doi.org/10.1016/s1099-4831(08)60049-8.

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Jack Li, Jie. "Chapter Four Applications of radical cyclization reactions in total syntheses of naturally occurring indole alkaloids." In Alkaloids: Chemical and Biological Perspectives. Elsevier, 2001. http://dx.doi.org/10.1016/s0735-8210(01)80018-2.

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Conference papers on the topic "Indole alkaloids; Substitution reactions"

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Stadlbauer, Wolfgang, Daniel Rieder, Birgit Schuiki, and Thomas Kappe. "Syntheses, Substitution and Cyclization Reactions of 7a,8,9,10,11a-Hexahydro-pyrido[3,2,1-jk]carbazoles With a Strychnos Alkaloids Partial Structure." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-a001.

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