Relevant bibliographies by topics / Indole moiety

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Indole moiety'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Indole moiety"

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Li, Jiao, and Chun-Lin Zhuang. "Natural Indole Alkaloids from Marine Fungi: Chemical Diversity and Biological Activities." Pharmaceutical Fronts 03, no. 04 (2021): e139-e163. http://dx.doi.org/10.1055/s-0041-1740050.

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The indole scaffold is one of the most important heterocyclic ring systems for pharmaceutical development, and serves as an active moiety in several clinical drugs. Fungi derived from marine origin are more liable to produce novel indole-containing natural products due to their extreme living environments. The indole alkaloids from marine fungi have drawn considerable attention for their unique chemical structures and significant biological activities. This review attempts to provide a summary of the structural diversity of marine fungal indole alkaloids including prenylated indoles, diketopip
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Gaikwad, Vijay. "Review of indole, A versatile pharmacophoric moiety." Current Trends in Pharmacy and Pharmaceutical Chemistry 6, no. 2 (2024): 34–40. http://dx.doi.org/10.18231/j.ctppc.2024.011.

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Indole is a heterocyclic compound, known for its alluring smell. Indole contributes to the rich aroma of various flowers such as jasmine and orange blossoms. Indole plays a vital role in numerous biological processes, including hormone regulation, neurotransmission, and immune response. Indole derivatives serve as a foundation for developing drugs in several therapeutic areas, such as antiviral, anticancer, and psychiatric medications.
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Padrtová, Tereza, Pavlína Marvanová, Renáta Kubínová, et al. "Indol-2-Carboxylic Acid Esters Containing N-Phenylpiperazine Moiety - Preparation and Cholinesterase-inhibiting Activity." Current Organic Synthesis 17, no. 7 (2020): 576–87. http://dx.doi.org/10.2174/1570179417666200619132218.

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Background: The indole derivatives and the N-phenylpiperazine fragment represent interesting molecular moieties suitable for the research of new potentially biologically active compounds. This study was undertaken to identify if indol-2-carboxylic acid esters containing N-phenylpiperazine moiety possess acetylcholinesterase and butyrylcholinesterase inhibitory activity. Materials and Methods: The study dealt with the synthesis of a novel series of analogs of 1H-indole-2- carboxylic acid and 3-methyl-1H-indole-2-carboxylic acid. The structure of the derivatives was represented by the indolylcar
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Qin, Wenling, Nan Zhang, Yige Li, and Zhili Chen. "Direct Preparation of Indole Hemiaminals through Organocatalytic Nucleophilic Addition of Indole to Aldehydes." Synthesis 50, no. 20 (2018): 4063–70. http://dx.doi.org/10.1055/s-0037-1610453.

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Hemiaminals are common in natural products as well as bioactive compounds. Hemiaminals with an indole moiety are particularly attractive due to the significant bioactivity of indoles. Herein, we reported an efficient organocatalyzed indole N-1 nucleophilic addition of α-oxoaldehydes to deliver various indole hemiaminals in good yields (up to 92%) and excellent regioselectivities with DABCO or triethylamine as the catalyst. The method is characterized by mild reaction conditions, widely available reagents, and general substrate scope, and it is also applicable to late-stage transformations with
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Hájíček, Josef. "A Review on Recent Developments in Syntheses of the post-Secodine Indole Alkaloids. Part II: Modified Alkaloid Types." Collection of Czechoslovak Chemical Communications 72, no. 7 (2007): 821–98. http://dx.doi.org/10.1135/cccc20070821.

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The second part of the planned review on developments in the field of total and formal total synthesis of the post-secodine indole alkaloids concentrates on modified alkaloid types, i.e. those skeletons derived from primary types by formation of additional and/or rupture of existing bonds, while connectivities next to indol(e)ine moiety remain intact. It thus reviews the synthesis of alkaloids of quebrachamine/cleavamine type including VLB-bis-indoles, rhazinilam type, aspidofractinine/kopsane and kopsifoline type, as well as kopsijasminilam alkaloids, lapidilectine B and danuphylline. It cove
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Naraboli, Basavaraj Shivabasappa, and Jayaprakash Sharanappa Biradar. "SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF INDOLE DERIVATIVES BEARING BENZIMIDAZOLE/BENZOTHIAZOLE MOIETY." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 8 (2017): 128. http://dx.doi.org/10.22159/ijpps.2017v9i8.19725.

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Objective: The present work deals with the synthesis and characterization of biologically active new indole derivatives viz., 2-((1H-benzo[d]imidazol-2-yl)thio)-N-(4-(3-(1H-indol-3-yl)acryloyl)phenyl)acetamide 6a-d, N-(4-(3-(1H-indol-3-yl)acryloyl)phenyl)-2-((5-methoxy-1H-benzo[d]imidazol-2-yl)thio)acetamide 7a-d and N-(4-(3-(1H-indol-3-yl)acryloyl)phenyl)-2-(benzo[d]thiazol-2-ylthio)acetamide 8a-d.Methods: All these newly synthesized compounds were screened for their in vitro antimicrobial activity by an agar plate diffusion method, antioxidant activities: like 1,1-diphenyl-2-picryl hydrazyl
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Gardette, Daniel, Jean-Claude Gramain, Marie-Eve Lepage, and Yves Troin. "Photocyclization of aryl enaminones. An efficient route to indole alkaloid synthons." Canadian Journal of Chemistry 67, no. 2 (1989): 213–19. http://dx.doi.org/10.1139/v89-036.

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The photocyclization of enaminones was extended to aryl enaminones bearing a substituent on the aromatic moiety. This reaction was studied in order to achieve the synthesis of indole alkaloid synthons. Trials of regioselectivity control were made by using groups with enhanced steric hindrance. The reactivity of secondary enaminones was tested, and the ratio of C-alkylation to N-alkylation was shown to be dependent on the nature of the aromatic substituent. During this work, new hexahydrocarbazolones were synthesized, with substituents on the A ring or the modified C ring. Keywords: photocycliz
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Selvanayagam, S., B. Sridhar, S. Kathiravan, and R. Raghunathan. "Methyl (2Z)-2-[(2-formyl-3-methyl-1H-indol-1-yl)methyl]-3-(4-methoxyphenyl)prop-2-enoate." Acta Crystallographica Section E Structure Reports Online 70, no. 4 (2014): o431—o432. http://dx.doi.org/10.1107/s1600536814005261.

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In the title indole derivative, C22H21NO4, the dihedral angle between the benzene and pyrrole rings of indole moiety is 1.8 (1)°. The plane of the 4-methoxyphenyl ring is oriented with a dihedral angle of 60.7 (1)° with respect to the plane of the indole moiety. The molecular packing is stabilized by C—H...O hydrogen bonds which form a V-shaped chain arrangement along thebcplane of the unit cell. In addition to this, C—H...π and π–π interactions [centroid–centroid distances = 3.8102 (11) and 3.8803(12) Å], which run along theb-axis direction, stabilize the molecular packing.
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Zhang, Dongdong, Yanhong Shi, Jingyi Li, et al. "Alkaloids with Nitric Oxide Inhibitory Activities from the Roots of Isatis tinctoria." Molecules 24, no. 22 (2019): 4033. http://dx.doi.org/10.3390/molecules24224033.

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As our ongoing research project on Ban Lan Gen (Isatis tinctoria roots), a total of 23 alkaloids were obtained. Compounds 1 and 2 contain an unusual C–C bond between the 2(1H)-quinolinone moiety and the phenol moiety and between the 2(1H)-quinolinone moiety and the 1H-indole moiety, respectively. Compound 3 possesses an unusual carbon skeleton and its putative biosynthetic pathway was discussed, and Compound 23 was deduced as a new indole alkaloid glycoside. Compounds 4–7 were identified as four new natural products by extensive spectroscopic experiments. Additionally, the anti-inflammatory ac
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Kochetkov, Konstantin A., Olga N. Gorunova, and Natalia A. Bystrova. "Biologically Oriented Hybrids of Indole and Hydantoin Derivatives." Molecules 28, no. 2 (2023): 602. http://dx.doi.org/10.3390/molecules28020602.

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Indoles and hydantoins are important heterocycles scaffolds which present in numerous bioactive compounds which possess various biological activities. Moreover, they are essential building blocks in organic synthesis, particularly for the preparation of important hybrid molecules. The series of hybrid compounds containing indoles and imidazolidin-2-one moiety with direct C–C bond were synthesized using an amidoalkylation one-pot reaction. All compounds were investigated as a growth regulator for germination, growth and development of wheat seeds (Triticum aestivum L). Their effect on drought r
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Dissertations / Theses on the topic "Indole moiety"

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Engqvist, Robert. "Syntheses of some tri- and tetracyclic heterocycles containing an indole moiety /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-161-X/.

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Chang, Ting-Wei, and 張庭瑋. "Preparations of Secondary Phosphine Oxides Containing Indole Moiety and Their Derived Palladium Complexes: Applications in Heck-Type Catellani Reactions." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/56773684076508112642.

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碩士<br>國立中興大學<br>化學系所<br>103<br>Several new secondary phosphine oxides (SPOs) containing indole moiety were prepared. These new compounds are air- and moisture-stable preligands and advantageous for the purpose of storage. The structures of pallidium complexes might be stabilized by these SPOs. Pallidium complexes (3b & 4b) were obtained from the reactions of PdX2 (X = Cl, Br) with ligand (2b) and structures were determined by single-crystal X-ray diffraction methods. Applications of these SPO ligands (2a-2c) in palladium-catalyzed Heck-type Catellani reactions exhibited acceptable effi
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"Medindo Eficiência Relativa de Escolas Municipais da Cidade do Rio Grande Rs Usando A Abordagem Dea Data Envelopment Analysis." Tese, Programa de Pós Graduação em Engenharia de Produção, 1995. http://www.eps.ufsc.br/disserta/moita/indice/index.html.

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Book chapters on the topic "Indole moiety"

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Bohren, Craig F., and Bruce A. Albrecht. "Energy, Momentum, and Mass Transfer." In Atmospheric Thermodynamics, 2nd ed. Oxford University PressOxford, 2023. http://dx.doi.org/10.1093/oso/9780198872702.003.0007.

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Abstract Conduction, convection, and radiation are not completely independent energy transfer modes. Energy transfer within a stationary medium is the product of its thermal conductivity and a temperature gradient. Except in thin stagnant films near solid boundaries, energy is transferred in fluids by buoyancy-driven convection at all scales. Film thickness depends on convection in a complicated way. All thermal insulation—cork, wool, foams—exploits the low thermal conductivity of air immobilized in pores. The thermal conductivity of moist air is somewhat less than that of dry air. Cooling of
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Bhatt, Shreyas Anantray. "Psychrophiles." In Physiology, Genomics, and Biotechnological Applications of Extremophiles. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-7998-9144-4.ch005.

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Life on the Earth has evolved in the cold environments. Such cold habitats pose special challenges to the microbes in cold ecosystems, such as minimum metabolic activities, very limited nutrient availability, and often extreme conditions such as pH and salinity apart from temperature. Microbial communities surviving under these extreme conditions must have evolved complex structural and functional adaptations. Prokaryotic adaptations to cold environments are through physiological adaptations by increasing membrane fluidity through large amount of unsaturated fatty acids. These microbes also po
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Sposito, Garrison. "Soil Humus." In The Chemistry of Soils. Oxford University Press, 2016. http://dx.doi.org/10.1093/oso/9780190630881.003.0007.

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Biomoleculesare compounds synthesized to sustain the life cycles of organisms. In soil humus, they are usually products of litter degradation, root excretion, and microbial metabolism, ranging in molecular structure from simple organic acids to complex biopolymers. Organic acids are among the best-characterized biomolecules. Table 3.1 lists five aliphatic (meaning the C atoms are arranged in open-chain structures) organic acids associated commonly with the soil microbiome. These acids contain the unit R—COOH, where COOH is the carboxyl groupand R represents either H or an organic moiety. The c
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Conference papers on the topic "Indole moiety"

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Chawla, S. K., and J. H. Payer. "Thermodynamic Perspective of Indoor Atmospheric Corrosion." In CORROSION 1990. NACE International, 1990. https://doi.org/10.5006/c1990-90226.

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Abstract The thermodynamics of indoor atmospheric corrosion are examined in a model system of copper exposed to moist air containing various levels of sulfur dioxide. Previous experimental work has shown that in such a system the initial tarnish film comprises a mixture of copper oxide and copper sulfide. Equilibrium criteria are used to calculate the ionic composition of the adsorbed water layer on the surface of the untarnished and the tarnished metal at various gas precursor concentrations. Using the adlayer chemistry, the electrode potentials of the redox reactions in the system are determ
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Stallbaumer, Emily, Adan Cernas, Amy Betz, and Melanie Derby. "Ice Formation due to Condensation of Moist Air on Commercial Wicks." In ASME 2020 18th International Conference on Nanochannels, Microchannels, and Minichannels collocated with the ASME 2020 Heat Transfer Summer Conference and the ASME 2020 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/icnmm2020-1088.

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Abstract Heat pipes are valuable heat transfer devices that can be used in space; however, when exposed to the extremely low temperature of space, the working fluid can freeze. Currently, there are different methods to help mitigate freezing effects, including non-condensable gas-charged heat pipes and understanding ice formation on surfaces (e.g., typically surfaces with hydrophobic coatings). However, there is limited research about ice formation on wicks. Different wicking structures may delay freezing or mitigate freezing effects. This paper will investigate ice formation on two surfaces —
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Federici, A. B., C. De Romeuf, P. G. De Groot, et al. "INCREASED ADHESIVE PROPERTIES OF THE CARBOHYDRATE-MODIFIED VON WILLEBRAND FACTOR (CHO-VWF): CRITICAL ROLE OF THE MULTIMERIC STRUCTURE AND CORRELATION WITH PLATELET AGGREGATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644094.

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We have reexplored the role of the carbohydrate moiety (CHO) on the von Willebrand Factor (vWF) structure and function by critically evaluating its different purification steps and modifications in CHO content by specific enzymes. Structural and functional assays have been evaluated separately in each laboratory (Milano and Lille) and jointly in Utrecht during several organized experiments. Under our conditions, the CHOVWFs obtained were characterized by less than 5% of sialic acid "(Neu)asevWF" and about 45% of D-Galactose "(Neu-Gal)ase-vWF" remaining, by increased electrophoretic mobility wi
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Hensley, Joshua L., and James E. Bryan. "Fundamental Investigation of Direct Contact Heat Exchange for Application in HVAC Systems: A Case Study." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-16059.

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An air conditioning system based on a direct contact heat and mass transfer process between water and air may offer benefits such as increased energy efficiency, temperature and humidity control, and improved indoor air quality. To investigate the feasibility of this type of technology, a numeric model is used to study the heat and mass transfer between a single droplet and moist air to gain fundamental insight into the heat and mass transfer process. Further, preliminary experiments are performed in a low speed temperature and humidity controlled wind tunnel to validate some of the models fin
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Zhang, J. W., S. Wang, S. L. Yang, X. Chen, W. J. Wei, and L. H. Li. "Laboratory Study on the Strength Deterioration Characteristics of Solid Potash Ore Samples in Moist Environment." In 58th U.S. Rock Mechanics/Geomechanics Symposium. ARMA, 2024. http://dx.doi.org/10.56952/arma-2024-0306.

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ABSTRACT: Potassium salt rock is a typical discontinuous heterogeneous material formed naturally, which is mainly composed of carnallite, sylvite, halite and so on. Potassium salt is widely used in various industry fields (such as agriculture, chemical industry, medicine, metallurgy, electroplating, printing and dyeing, glass, etc.) and has a large demand. One of the important sources is the mining of solid potassium salt mines. Through the laboratory test of solid potassium salt ore samples obtained from an underground potassium salt mine in a mine in Laos, various mechanical parameter data o
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Dutta, Piyush K. "Role of Frozen Water on the Fracture Growth of Composite Materials." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-2164.

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Abstract Delamination of composites is a fairly common failure mechanism. Its sensitivity to the interference of environmental parameters e.g. temperature and moisture is generally well known. Accelerated delamination induced by moisture at high temperature, which lowers the Tg (the glass transition temperature of the matrix), has been studied for decades. Also, predictive tests for durability of composite materials suggest boiling of composites as a technique to develop the predictive index for lifecycle prediction (Dewimille and Burnsell, 1983). However, these approaches ignore the dramatic
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Reports on the topic "Indole moiety"

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Lurie, Susan, John Labavitch, Ruth Ben-Arie, and Ken Shackel. Woolliness in Peaches and Nectarines. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7570557.bard.

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The overall goal of the research was to understand the processes involved in the development of woolliness in peaches and nectarines. Four specific hypotheses were proposed and in the course of the research evidence was gathered t support two of them and to not support two others. The hypotheses and a summary of the evidence are outlined below. 1. That woolliness arises from an imbalance between the activities of the cell wall pectin degrading enzymes. Using 'Flavortop' nectarines and 'Hermoza' peaches as model systems, storage regimes were manipulated to induce or prevent woolliness. The expr
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