Academic literature on the topic 'Indolizine – Derivatives'

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Journal articles on the topic "Indolizine – Derivatives"

1

Sekgota, Khethobole C., Michelle Isaacs, Heinrich C. Hoppe, et al. "Propylphosphonic acid anhydride–mediated amidation of Morita–Baylis–Hillman–derived indolizine-2-carboxylic acids." Journal of Chemical Research 45, no. 7-8 (2021): 674–78. http://dx.doi.org/10.1177/1747519820987156.

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Propylphosphonic acid anhydride has been successfully used as a coupling agent in the synthesis of a series of indolizine-2-carboxamido derivatives from indolizine-2-carboxylic acid and its 3-acetylated analogue. The acid substrates were obtained by saponification of the corresponding methyl esters produced, in turn, selectively and efficiently, by time-controlled cyclisation of a single Morita–Baylis–Hillman adduct. Various amino and hydrazino compounds with medicinal potential have been used to prepare indolizine-2-carboxamido and hydrazido derivatives.
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2

Zhang, Yi-Zhu, Feng-Tao Sheng, Zuoquan Zhu, et al. "Organocatalytic C3-functionalization of indolizines: synthesis of biologically important indolizine derivatives." Organic & Biomolecular Chemistry 18, no. 29 (2020): 5688–96. http://dx.doi.org/10.1039/d0ob01230k.

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A Brønsted acid-catalyzed C3-alkylation of indolizines has been established with different electrophiles (E), which synthesized a series of C3-functionalized indolizines in overall good yields (up to 89%).
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3

Cai, Qun, Yan-Ping Zhu, Yang Gao, Jing-Jing Sun, and An-Xin Wu. "A direct method for the synthesis of indolizine derivatives from easily available aromatic ketones, pyridines, and acrylonitrile derivatives." Canadian Journal of Chemistry 91, no. 6 (2013): 414–19. http://dx.doi.org/10.1139/cjc-2012-0534.

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A concise and efficient strategy has been proposed to synthesize indolizine derivatives from easily available aryl or heteroaryl methyl ketones, pyridines, and acrylonitriles. The mechanistic pathway involved the integration of iodination, pyridinium ylide synthesis, and 1,3-dipolar cycloaddition. The protocols were found to be highly efficient in terms of high yields, operational simplicity, mild reaction conditions, and easy workup. This method has provided an important supplement for the synthesis of indolizine derivatives via a novel tandem synthesis.
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4

Au-Alvarez, O., V. A. Tafeenko, and L. A. Aslanov. "Structural study of indolizine derivatives." Acta Crystallographica Section A Foundations of Crystallography 52, a1 (1996): C274. http://dx.doi.org/10.1107/s010876739608854x.

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5

Bonnaud, Bernard, Dennis Bigg, and Jean-François Patoiseau. "Synthesis of novel indolizine derivatives." Journal of Heterocyclic Chemistry 28, no. 8 (1991): 1927–32. http://dx.doi.org/10.1002/jhet.5570280820.

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6

López, Luis A., and Javier González. "Copper(i)-carbenes as key intermediates in the [3 + 2]-cyclization of pyridine derivatives with alkenyldiazoacetates: a computational study." Organic & Biomolecular Chemistry 17, no. 3 (2019): 646–54. http://dx.doi.org/10.1039/c8ob02676a.

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This work reports a computational study of the copper(i)-catalyzed regioselective synthesis of indolizine derivatives through the [3 + 2]-cyclization reaction of vinyldiazo acetates and pyridine derivatives.
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7

Hayford, A., and J. Kaloko Jr. "Synthesis of Indolizine Derivatives by Electrocyclization." Synfacts 2006, no. 01 (2005): 0025. http://dx.doi.org/10.1055/s-2005-921691.

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8

Coffinier, Didier, Laurent El Kaim, and Laurence Grimaud. "Nef-Perkow Access to Indolizine Derivatives." Synlett 2010, no. 16 (2010): 2474–76. http://dx.doi.org/10.1055/s-0030-1258569.

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9

Dohmen, Christoph, Heiko Ihmels, Rouven Kreienmeier, and Brian O. Patrick. "Synthesis of a crystallochromic indolizine dye by a base- and catalyst-free photochemical route." Chemical Communications 55, no. 74 (2019): 11071–74. http://dx.doi.org/10.1039/c9cc04730a.

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Irradiation of 2-benzoyl-N-benzylpyridinium derivatives and dimethyl acetylene dicarboxylate resulted in the formation of inolizine derivatives, one which was found to be the first example of a crystallochromic indolizine.
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10

Wang, Yefei, Zhen Yang, Fengtao Zhan, et al. "Indolizine quaternary ammonium salt inhibitors part II: a reinvestigation of an old-fashioned strong acid corrosion inhibitor phenacyl quinolinium bromide and its indolizine derivative." New Journal of Chemistry 42, no. 15 (2018): 12977–89. http://dx.doi.org/10.1039/c8nj02505c.

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