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Relevant bibliographies by topics / Induced mutations

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Academic literature on the topic 'Induced mutations'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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Journal articles on the topic "Induced mutations"

1

Keightley, Peter D., Esther K. Davies, Andrew D. Peters, and Ruth G. Shaw. "Properties of Ethylmethane Sulfonate-Induced Mutations Affecting Life-History Traits in Caenorhabditis elegans and Inferences About Bivariate Distributions of Mutation Effects." Genetics 156, no. 1 (2000): 143–54. http://dx.doi.org/10.1093/genetics/156.1.143.

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Abstract The homozygous effects of ethylmethane sulfonate (EMS)-induced mutations in Caenorhabditis elegans are compared across life-history traits. Mutagenesis has a greater effect on early than late reproductive output, since EMS-induced mutations tend to cause delayed reproduction. Mutagenesis changes the mean and variance of longevity much less than reproductive output traits. Mutations that increase total or early productivity are not detected, but the net effect of mutations is to increase and decrease late productivity to approximately equal extents. Although most mutations decrease lon

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Sugiyama, Tomohiko. "Biochemical reconstitution of heat-induced mutational processes." PLOS ONE 19, no. 9 (2024): e0310601. http://dx.doi.org/10.1371/journal.pone.0310601.

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Non-enzymatic spontaneous deamination of 5-methylcytosine, producing thymine, is the proposed etiology of cancer mutational signature 1, which is the most predominant signature in all cancers. Here, the proposed mutational process was reconstituted using synthetic DNA and purified proteins. First, single-stranded DNA containing 5-methylcytosine at CpG context was incubated at an elevated temperature to accelerate spontaneous DNA damage. Then, the DNA was treated with uracil DNA glycosylase to remove uracil residues that were formed by deamination of cytosine. The resulting DNA was then used as

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3

Ram, Yoav, and Lilach Hadany. "Stress-induced mutagenesis and complex adaptation." Proceedings of the Royal Society B: Biological Sciences 281, no. 1792 (2014): 20141025. http://dx.doi.org/10.1098/rspb.2014.1025.

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Because mutations are mostly deleterious, mutation rates should be reduced by natural selection. However, mutations also provide the raw material for adaptation. Therefore, evolutionary theory suggests that the mutation rate must balance between adaptability —the ability to adapt—and adaptedness —the ability to remain adapted. We model an asexual population crossing a fitness valley and analyse the rate of complex adaptation with and without stress-induced mutagenesis (SIM)—the increase of mutation rates in response to stress or maladaptation. We show that SIM increases the rate of complex ada

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4

Szikriszt, Bernadett, Ádám Póti, Orsolya Pipek, et al. "A comprehensive survey of the mutagenic impact of common cancer cytotoxics." Genome Biology 17, no. 1 (2016): 99. https://doi.org/10.1186/s13059-016-0963-7.

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<strong>Background: </strong>Genomic mutations caused by cytotoxic agents used in cancer chemotherapy may cause secondary malignancies as well as contribute to the evolution of treatment-resistant tumour cells. The stable diploid genome of the chicken DT40 lymphoblast cell line, an established DNA repair model system, is well suited to accurately assay genomic mutations.<strong>Results: </strong>We use whole genome sequencing of multiple DT40 clones to determine the mutagenic effect of eight common cytotoxics used for the treatment of millions of patients worldwide. We determine the spontaneou

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Keyse, S. M., F. Amaudruz, and R. M. Tyrrell. "Determination of the spectrum of mutations induced by defined-wavelength solar UVB (313-nm) radiation in mammalian cells by use of a shuttle vector." Molecular and Cellular Biology 8, no. 12 (1988): 5425–31. http://dx.doi.org/10.1128/mcb.8.12.5425-5431.1988.

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Mutations induced by UVB (313-nm) radiation, a wavelength in the region of peak effectiveness for sunlight-induced skin cancer in humans, have been analyzed at the sequence level in simian cells by using a plasmid shuttle vector (pZ189). We find that significant differences exist between the types of mutations induced by this solar wavelength and those induced by nonsolar UVC (254-nm) radiation. Compared with 254-nm radiation, 313-nm radiation induces more deletions and insertions in the region sequenced. In addition, although the types of base substitutions induced by the two wavelengths are

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Keyse, S. M., F. Amaudruz, and R. M. Tyrrell. "Determination of the spectrum of mutations induced by defined-wavelength solar UVB (313-nm) radiation in mammalian cells by use of a shuttle vector." Molecular and Cellular Biology 8, no. 12 (1988): 5425–31. http://dx.doi.org/10.1128/mcb.8.12.5425.

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Mutations induced by UVB (313-nm) radiation, a wavelength in the region of peak effectiveness for sunlight-induced skin cancer in humans, have been analyzed at the sequence level in simian cells by using a plasmid shuttle vector (pZ189). We find that significant differences exist between the types of mutations induced by this solar wavelength and those induced by nonsolar UVC (254-nm) radiation. Compared with 254-nm radiation, 313-nm radiation induces more deletions and insertions in the region sequenced. In addition, although the types of base substitutions induced by the two wavelengths are

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7

Imai, Yoshiyuki, Benjamin Feldman, Alexander F. Schier, and William S. Talbot. "Analysis of Chromosomal Rearrangements Induced by Postmeiotic Mutagenesis With Ethylnitrosourea in Zebrafish." Genetics 155, no. 1 (2000): 261–72. http://dx.doi.org/10.1093/genetics/155.1.261.

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Abstract Mutations identified in zebrafish genetic screens allow the dissection of a wide array of problems in vertebrate biology. Most screens have examined mutations induced by treatment of spermatogonial (premeiotic) cells with the chemical mutagen N-ethyl-N-nitrosourea (ENU). Treatment of postmeiotic gametes with ENU induces specific-locus mutations at a higher rate than premeiotic regimens, suggesting that postmeiotic mutagenesis protocols could be useful in some screening strategies. Whereas there is extensive evidence that ENU induces point mutations in premeiotic cells, the range of mu

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DuBridge, R. B., P. Tang, H. C. Hsia, P. M. Leong, J. H. Miller, and M. P. Calos. "Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system." Molecular and Cellular Biology 7, no. 1 (1987): 379–87. http://dx.doi.org/10.1128/mcb.7.1.379-387.1987.

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We developed highly sensitive shuttle vector systems for detection of mutations formed in human cells using autonomously replicating derivatives of Epstein-Barr virus (EBV). EBV vectors carrying the bacterial lacI gene as the target for mutation were established in human cells and later returned to Escherichia coli for rapid detection and analysis of lacI mutations. The majority of the clonal cell lines created by establishment of the lacI-EBV vector show spontaneous LacI- frequencies of less than 10(-5) and are suitable for studies of induced mutation. The ability to isolate clonal lines repr

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DuBridge, R. B., P. Tang, H. C. Hsia, P. M. Leong, J. H. Miller, and M. P. Calos. "Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system." Molecular and Cellular Biology 7, no. 1 (1987): 379–87. http://dx.doi.org/10.1128/mcb.7.1.379.

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We developed highly sensitive shuttle vector systems for detection of mutations formed in human cells using autonomously replicating derivatives of Epstein-Barr virus (EBV). EBV vectors carrying the bacterial lacI gene as the target for mutation were established in human cells and later returned to Escherichia coli for rapid detection and analysis of lacI mutations. The majority of the clonal cell lines created by establishment of the lacI-EBV vector show spontaneous LacI- frequencies of less than 10(-5) and are suitable for studies of induced mutation. The ability to isolate clonal lines repr

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Lambert, I. B., A. J. Gordon, B. W. Glickman, and D. R. McCalla. "The influence of local DNA sequence and DNA repair background on the mutational specificity of 1-nitroso-8-nitropyrene in Escherichia coli: inferences for mutagenic mechanisms." Genetics 132, no. 4 (1992): 911–27. http://dx.doi.org/10.1093/genetics/132.4.911.

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Abstract We have examined the mutational specificity of 1-nitroso-8-nitropyrene (1,8-NONP), an activated metabolite of the carcinogen 1,8-dinitropyrene, in the lacI gene of Escherichia coli strains which differ with respect to nucleotide excision repair (+/- delta uvrB) and MucA/B-mediated error-prone translesion synthesis (+/- pKM101). Several different classes of mutation were recovered, of which frameshifts, base substitutions, and deletions were clearly induced by 1,8-NONP treatment. The high proportion of point mutations (&gt; 92%) which occurred at G.C sites correlates with the perce

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Dissertations / Theses on the topic "Induced mutations"

1

Luo, Da. "Transposon-induced mutations in Antirrhinum majus." Thesis, University of East Anglia, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280022.

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Vilariño-Güell, Carles. "Analysis of germline mutations induced by chemicals." Thesis, University of Leicester, 2002. http://hdl.handle.net/2381/9415.

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The high abundance of chemical pollutants in the environment represents a genetic risk to humans. The development of reliable and sensitive tests for the analysis of the genetic effects of exposure to chemical mutagens is required. Previous work has shown that expanded simple tandem repeat (ESTR) loci provide a sensitive system for monitoring radiation-induced mutation in the mouse germline. Here, the results of the first systematic study on germline mutation induction at mouse ESTR loci by chemical mutagens are presented. Mutation rates at two ESTR loci were studied in the germline of male mi

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Yauk, Carole Lyn. "Germline minisatellite mutations in herring gulls, induced mutations at colonies situated near steel mills." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ51024.pdf.

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Yauk, Carole Lyn. "Germline minisatellite mutations in herring gulls : induced mutations at colonies situated near steel mills /." *McMaster only, 1998.

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Song, H. "Molecular analysis of genotoxin induced mutations in rodents." Thesis, Swansea University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639088.

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The Restriction Site Mutation (RSM) assay was employed to study p53 gene mutations induced <I>in vivo</I> by N-ethyl-N-nitrosourea (ENU), cyclophosphamide (CP), and <I>in vitro</I> by 4-Nitroquinoline 1-oxide (4NQO). The effectiveness of the RSM assay was further confirmed by detecting 193 mutant sites in liver, kidney, lung, and testis of animals treated <I>in vivo</I>, as well as in mammalian cell culture treated <I>in vitro</I>. Rare spontaneous germline mutations were for the first time detected by the RSM assay. This further emphasizes the sensitivity of the RSM assay. These results imply

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Davies, Margaret Jacqueline. "Molecular analysis of chemically induced mutations in mammalian cells." Thesis, University of Surrey, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359881.

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Estes, Suzanne R. "Properties of spontaneous and induced mutations in Caenorhabditis elegans /." view abstract or download file of text, 2002. http://wwwlib.umi.com/cr/uoregon/fullcit?p3061944.

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Thesis (Ph. D.)--University of Oregon, 2002.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 101-112). Also available for download via the World Wide Web; free to University of Oregon users.

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Haworth, Kim E. "Investigation of mutations induced by radiation and restriction endonucleases." Thesis, University of St Andrews, 1995. http://hdl.handle.net/10023/14327.

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The effects of gamma radiation and restriction endonuclease (RE) induced DNA double strand breaks (dsb) upon the mutation frequency and the surviving fraction of three Chinese hamster cell lines V79-4, CHO-K1 and an X-ray sensitive dsb repair deficient cell line xrs-5 were studied. The X-ray sensitive xrs-5 cell line was shown to be more sensitive to both the lethal and the mutagenic effects of gamma radiation having a substantially lower surviving fraction and a higher thymidine kinase (tk) mutation frequency per unit dose than the parental CHO-K1 cells. The frequency of induced hprt- mutatio

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Warburton, N. "The effects of induced mutations on the expression of cloned genes." Thesis, University of Leeds, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354312.

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Lam, Cindy. "Effects of APOBEC3-Induced Mutations on HIV-1 Expression and Latency." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39811.

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One of the greatest barriers to curing HIV-1 is the ability of the virus to establish a state of latent infection within infected cells. During viral latency, the virus lies dormant in the form of an integrated, replication-competent provirus within the infected cell. In this state, the virus is undetectable by the host immune system and is unaffected by antiretroviral drugs due to extremely weak or null transcription. These viruses, however, can be induced to produce infectious virus later on and propagate the infection as well as reseed the latent reservoir. The factors that lead to the esta

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Books on the topic "Induced mutations"

1

Luo, Da. Transposon-induced mutations in Antirrhinum majus. University of East Anglia, 1990.

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2

Y, Shu Q., and Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, eds. Induced plant mutations in the genomics era. Food and Agricultural Organization of the United Nations, 2009.

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3

Jain, S. M., D. S. Brar, and B. S. Ahloowalia, eds. Somaclonal Variation and Induced Mutations in Crop Improvement. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-015-9125-6.

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Goldstein, L. S. Radiation-induced germ cell mutations-- their detection and modification. Defense Nuclear Agency, 1987.

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Goldstein, L. S. Radiation-induced germ cell mutations-- their detection and modification. Defense Nuclear Agency, 1987.

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United States. Defense Nuclear Agency. and University of California, San Francisco., eds. Radiation-induced germ cell mutations-- their detection and modification. Defense Nuclear Agency, 1987.

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Goldstein, L. S. Radiation-induced germ cell mutations-- their detection and modification. Defense Nuclear Agency, 1987.

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Workshop on the Improvement of Grain Legume Production Using Induced Mutations (1986 Pullman, Wash.). Improvement of grain legume production using induced mutations: Proceedings of a Workshop on the Improvement of Grain Legume Production Using Induced Mutations. International Atomic Energy Agency, 1988.

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Workshop, on the Improvement of Grain Legume Production using Induced Mutations (1986 Pullman Washington). Improvement of grain legume production using induced mutation: Proceedings of a Workshop of the Improvement of Grain Legume Production using Induced Mutations. International Atomic Energy Agency, 1988.

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International Symposium on the Use of Induced Mutations and Molecular Techniques for Crop Improvement (1995 Vienna, Austria). Induced mutations and molecular techniques for crop improvement: Proceedings of an International Symposium on the Use of Induced Mutations and Molecular Techniques for Crop Improvement. International Atomic Energy Agency, 1995.

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Book chapters on the topic "Induced mutations"

1

Micke, A., and B. Donini. "Induced mutations." In Plant Breeding. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1524-7_5.

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Sigurbjörnsson, B. "Induced Mutations." In Crop Breeding. American Society of Agronomy, Crop Science Society of America, 2012. http://dx.doi.org/10.2135/1983.cropbreeding.c8.

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Datta, Subodh Kumar. "Detection of Mutations." In Induced Mutation Breeding. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-9489-0_15.

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Abe, Tomoko, Hiroyuki Ichida, Yoriko Hayashi, et al. "Ion beam mutagenesis - an innovative and effective method for plant breeding and gene discovery." In Mutation breeding, genetic diversity and crop adaptation to climate change. CABI, 2021. http://dx.doi.org/10.1079/9781789249095.0042.

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Abstract We have developed a unique technology for mutation induction of plants using energetic ion beams at the RI Beam Factory (RIBF) of Rikagaku Kenkyūjo (RIKEN) (Institute of Physical and Chemical Research). Ion beams effectively induce mutations at relatively low doses without severely inhibiting growth. The irradiation treatment can be given to various plant materials and mutation can be induced in a short time, between seconds and a few minutes. The linear energy transfer (LET) of ions depends on the nuclide and velocity. Since LET value affects the mutation frequency, it is an importan

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Kiefer, J. "Radiation Induced Mutations." In Fundamentals for the Assessment of Risks from Environmental Radiation. Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4585-5_35.

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Nakagawa, Hitoshi. "History of mutation breeding and molecular research using induced mutations in Japan." In Mutation breeding, genetic diversity and crop adaptation to climate change. CABI, 2021. http://dx.doi.org/10.1079/9781789249095.0003.

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Abstract Following the construction of the Gamma Field at the Institute of Radiation Breeding in 1960, mutation breeding was accelerated in Japan. The facility is used, with a radiation dose up to 2 Gy/day (ca. 300,000 times that of natural background), to induce mutations at a higher frequency than occurs in nature. There have been 318 direct- use mutant cultivars representing 79 species generated through irradiation of gamma-rays, X-rays, ion beams and chemicals and somaclonal variation. Approximately 79% of these direct-use cultivars were induced by radiation. There have been 375 indirect-u

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Bird, R. McK, and M. G. Neuffer. "Induced Mutations in Maize." In Plant Breeding Reviews. John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118061022.ch5.

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Jankowicz-Cieslak, Joanna, Florian Goessnitzer, Bradley J. Till, and Ivan L. Ingelbrecht. "Induced Mutagenesis and In Vitro Mutant Population Development in Musa spp." In Efficient Screening Techniques to Identify Mutants with TR4 Resistance in Banana. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-64915-2_1.

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AbstractMutagenesis of in vitro propagated bananas is an efficient method to introduce novel alleles and broaden genetic diversity. Mutations can be induced by treatment of plant cells with chemical mutagens or ionizing radiation. The FAO/IAEA Plant Breeding and Genetics Laboratory established efficient methods for mutation induction of in vitro shoot tips in banana using physical and chemical mutagens as well as methods for the efficient discovery of EMS-induced single nucleotide mutations in targeted genes or amplicons and identification of large genomic changes, including deletions and inse

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Priyadarshan, P. M. "Induced Mutations and Polyploidy Breeding." In PLANT BREEDING: Classical to Modern. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7095-3_16.

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Schum, A., and W. Preil. "Induced Mutations in Ornamental Plants." In Somaclonal Variation and Induced Mutations in Crop Improvement. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-015-9125-6_17.

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Conference papers on the topic "Induced mutations"

1

Ree, N. A., N. A. Potapova, N. S. Van Leiden, K. V. K.V. Gunbin, and K. I. Popadin. "EFFECT OF MUTAGENS ON THE STABILITY OF MITOCHONDRIAL GENOME." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-9.

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In our study, we explored how various mutagenic agents impact mitochondrial DNA (mtDNA) stability. We analyzed 2448 whole-genome sequencing samples, focusing on induced pluripotent stem cells exposed to environmental mutagens. Not all agents affected mtDNA content, but 13 increased mutations approximately twofold. The dominant mutation type was G>A, and 1,2-dimethylhydrazine (DMH) stood out as a distinctive mutagen.

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Stamo, Ilirjana, Ariana Ylli, and Andon Dodbiba. "Induced Mutations for Improving Production on Bread and Durum Wheat." In SIXTH INTERNATIONAL CONFERENCE OF THE BALKAN PHYSICAL UNION. AIP, 2007. http://dx.doi.org/10.1063/1.2733488.

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Ross, Jeffrey A., Esra Mutlu, Charly King, et al. "Abstract 3594: Mutations and DNA adducts induced by diesel exhaust particles." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-3594.

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Song, Zhiqing, and Yunzhang Liang. "Extremely Low Frequency Electric Field Induced Mutations in Escherichia Coli K12 Strains." In 2010 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2010. http://dx.doi.org/10.1109/icbbe.2010.5514939.

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Kamarauli, E. D., A. V. Vlasova, D. V. Perevozchikov, and I. V. Kirov. "ACTIVATION MOBILE ELEMENTS TRANSCRIPTION AND TRANSPOSITION USING NOVEL APPROACH OF VIRUS-INDUCED TE-STORM." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-188.

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In this work, we represent a new TE-storm method for activation plant mobile elements. Our approach is based on transient suppression of the transposon silencing mechanisms using recombinant viral constructs. The development of TE-storm opens new possibilities for introducing mutations into the genome using the natural biological mutagens — mobile elements

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Budi, Rahmad Setia, Irfan Suliansyah, Yusniwati, and Sobrizal. "Genetic Improvement of North Sumatra Upland Red Rice through Exploration and Induced Mutations." In International Conference on Multidisciplinary Research. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0008887702160224.

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Li, Yan, and Xiansheng Li. "Driver Workload Mutations Induced Road Analysis of Traffic Accidents in the Rural-Urban Continuum." In Third International Conference on Transportation Engineering (ICTE). American Society of Civil Engineers, 2011. http://dx.doi.org/10.1061/41184(419)539.

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Ou, Lin, Rong Chen, Tong Lin, Weijian Zhuang, and Lailong Cai. "Preliminary study on the biological effect of different laser-induced mutations in peanut seeds." In Optics and Optoelectronic Inspection and Control: Techniques, Applications, and Instruments, edited by Hong Liu and Qingming Luo. SPIE, 2000. http://dx.doi.org/10.1117/12.403964.

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Matić, Sanja, Milan Mladenović, Snežana Stanić, Nevena Tomašević, and Rino Ragno. "Hesperetin antigenotoxicity: Alleviation of chemically induced mutations on somatic cells understood through molecular modeling." In 6th International Electronic Conference on Medicinal Chemistry. MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07272.

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Heitz, F., K. Weber-Lassalle, C. Ernst, et al. "Chemotherapy-induced mutations in genes of clonal hematopoiesis increase the risk of myeloid neoplasms." In 64. Kongress der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe e. V. Georg Thieme Verlag, 2022. http://dx.doi.org/10.1055/s-0042-1756857.

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Reports on the topic "Induced mutations"

1

Barkan, A. Transposon-induced nuclear mutations that alter chloroplast gene expression. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/6686800.

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Lingle, Wilma. Centrosome Hypertrophy Induced by p53 Mutations Leads to Tumor Aneuploidy. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada392933.

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Rosenstein, Barry S. ATM Mutations and the Development of Severe Radiation-Induced Morbidity Following Radiotherapy for Breast Cancer. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada443650.

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Rosenstein, Barry S. ATM Mutations and the Development of Severe Radiation-Induced Morbidity Following Radiotherapy for Breast Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada428237.

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Rosenstein, Barry S. ATM Mutations and the Development of Severe Radiation-Induced Morbidity Following Radiotherapy for Breast Cancer. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada421135.

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Rosenstein, Barry S. ATM Mutations and the Development of Severe Radiation-Induced Morbidity Following Radiotherapy for Breast Cancer. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada458226.

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Barkan, A. Transposon-induced nuclear mutations that alter chloroplast gene expression. Annual report, September 1, 1991--August 31, 1992. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/10136698.

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Barkan, A. Transposon-induced nuclear mutations that alter chloroplast gene expression. Annual report, September 1, 1992--April 15, 1993. Office of Scientific and Technical Information (OSTI), 1993. http://dx.doi.org/10.2172/10189463.

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Whitham, Steven A., Amit Gal-On, and Tzahi Arazi. Functional analysis of virus and host components that mediate potyvirus-induced diseases. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7591732.bard.

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Abstract:

The mechanisms underlying the development of symptoms in response to virus infection remain to be discovered in plants. Insight into symptoms induced by potyviruses comes from evidence implicating the potyviral HC-Pro protein in symptom development. In particular, recent studies link the development of symptoms in infected plants to HC-Pro's ability to interfere with small RNA metabolism and function in plant hosts. Moreover, mutation of the highly conserved FRNK amino acid motif to FINK in the HC-Pro of Zucchini yellow mosaic virus (ZYMV) converts a severe strain into an asymptomatic strain,

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Grdina, D. J., N. Shigematsu, and J. L. Schwartz. Protection against radiation-induced mutations at the hprt locus by spermine and N,N{double_prime}-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278). WR-33278 and spermine protect against mutation induction. Office of Scientific and Technical Information (OSTI), 1994. http://dx.doi.org/10.2172/10172494.

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