Relevant bibliographies by topics / Infantile Spams

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Infantile Spams'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Infantile Spams"

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Daniels, Dee, Kelly Knupp, Tim Benke, Kristine Wolter-Warmerdam, Maura Moran, and Fran Hickey. "Infantile Spasms in Children With Down Syndrome: Identification and Treatment Response." Global Pediatric Health 6 (January 2019): 2333794X1882193. http://dx.doi.org/10.1177/2333794x18821939.

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Objectives. To evaluate infantile spasms in children with Down syndrome including assessment of efficacy of treatments, presence of treatment lag, and to identify risk factors that may predict the occurrence of infantile spasms in this population. Methods. Medical charts, electroencephalograms, and brain magnetic resonance images were evaluated in 37 children treated for infantile spasms at a single institution from 2005 to 2015. Results. Mean age at diagnosis was 9.16 months, with an average 1.38-month lag from spasms onset to start of medication. Prevalence of heart defects and pulmonary hyp
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Villegas, M., J. Murray, and E. Sell. "P.058 Ketogenic diet for medication refractory infantile spasms in patients with Down syndrome: experience at the Children’s Hospital of Eastern Ontario." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 52, s1 (2025): S30. https://doi.org/10.1017/cjn.2025.10229.

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Background: Ketogenic diet can be an effective alternative therapy for medication refractory infantile spasms. Infantile spasms are more prevalent in children with Down syndrome compared with the general population and often medication refractory. Methods: Charts of infants who presented to the Children’s Hospital of Eastern Ontario with Down syndrome and refractory infantile spams treated with ketogenic diet from 2012 to 2025 were reviewed. Clinical response defined by cessation of epileptic spasms and resolution of hypsarrhythmia. Diet ratio,tolerance, side effects, concomitant medications,
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Caraballo, Roberto Horacio, Victor Ruggieri, Gabriel Gonzalez, et al. "Infantile spams without hypsarrhythmia: A study of 16 cases." Seizure 20, no. 3 (2011): 197–202. http://dx.doi.org/10.1016/j.seizure.2010.11.018.

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Peiwei Zhao, Xuehua Peng, Sukun Luo, et al. "Identification and characterization of novel mutations in MOGS in a Chinese patient with infantile spams." neurogenetics 21, no. 2 (2020): 97–104. http://dx.doi.org/10.1007/s10048-019-00590-5.

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Harini, Chellamani, Sonal Sharda, Ann Marie Bergin, et al. "Detailed Magnetic Resonance Imaging (MRI) Analysis in Infantile Spasms." Journal of Child Neurology 33, no. 6 (2018): 405–12. http://dx.doi.org/10.1177/0883073818760424.

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Purpose: To evaluate initial magnetic resonance imaging (MRI) abnormalities in infantile spasms, correlate them to clinical characteristics, and describe repeat imaging findings. Methods: A retrospective review of infantile spasm patients was conducted, classifying abnormal MRI into developmental, acquired, and nonspecific subgroups. Results: MRIs were abnormal in 52 of 71 infantile spasm patients (23 developmental, 23 acquired, and 6 nonspecific) with no correlation to the clinical infantile spasm characteristics. Both developmental and acquired subgroups exhibited cortical gray and/or white
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Srinivas, Sujithra. "Infantile spasm: A review on the severity of epileptic encephalopathy." IP Indian Journal of Neurosciences 8, no. 1 (2022): 16–20. http://dx.doi.org/10.18231/j.ijn.2022.004.

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Infantile spasm (IS) comprises of both an age dependent epileptic seizure and distinctive seizure Onset in infants. In the recent past the key observation in classification and standardization of infantile spasm has culminated many recommendations in distinguishing and recognizing the seizure type and the epileptic syndrome or the West syndrome. The Infantile spasm is an early onset epileptic encephalopathy which presents unique electrographic and clinical features, these features are found in children in the middle of the first year of their birth .However the pathophysiology and the heteroge
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Malavika Gopi, Akshaya Suresh, Anandu H, Roshni P R, Mamatha M R, and Vinayan K P. "West syndrome - epileptic encephalopathy at early infancy." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 7492–94. http://dx.doi.org/10.26452/ijrps.v11i4.3951.

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West syndrome (WS), synonymously infantile spasm or epileptic spasm, is a rare type of epileptic encephalopathy occurring at early infancy that exists with variable life expectancy. It is the most common form of epileptic encephalopathy. WS presents with spasms marked by extensor or mixed movements with distinct electroencephalogram (EEG) pattern of hypsarrhythmia, flexor and psychomotor arrest. Children with west syndrome always depict abnormal EEG, but sometimes the abnormality is seen only during sleep. The incidence of infantile spasms is found closer to 1 in 2,000 children, that typically
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Malavika Gopi, Akshaya Suresh, Anandu H, Roshni P R, Mamatha M R, and Vinayan K P. "West syndrome - epileptic encephalopathy at early infancy." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 7492–94. http://dx.doi.org/10.26452/ijrps.v11i4.3951.

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West syndrome (WS), synonymously infantile spasm or epileptic spasm, is a rare type of epileptic encephalopathy occurring at early infancy that exists with variable life expectancy. It is the most common form of epileptic encephalopathy. WS presents with spasms marked by extensor or mixed movements with distinct electroencephalogram (EEG) pattern of hypsarrhythmia, flexor and psychomotor arrest. Children with west syndrome always depict abnormal EEG, but sometimes the abnormality is seen only during sleep. The incidence of infantile spasms is found closer to 1 in 2,000 children, that typically
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Haines, Stuart T., and Daniel T. Casto. "Treatment of Infantile Spasms." Annals of Pharmacotherapy 28, no. 6 (1994): 779–91. http://dx.doi.org/10.1177/106002809402800616.

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OBJECTIVE: To summarize and evaluate the literature regarding the clinical features, epidemiology, etiology, pathophysiology, and treatment of infantile spasms. DATA SOURCES: A literature search of articles from January 1966 to July 1993 using MEDLINE, EM-Base, and Current Concepts/Life Sciences, as well as bibliographies of relevant articles. STUDY SELECTION: All identified original and review publications regarding the clinical features, epidemiology, etiology, pathophysiology, and treatment of infantile spasms were reviewed. Emphasis was placed on original studies published since 1975. DATA
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Wang, Ling, Shannon Yarosz, Hosain Aghamoosa, Zachary Grinspan, and Anup D. Patel. "Validating an Algorithm to Identify Patients With Infantile Spasms Using Medical Claims." Journal of Child Neurology 33, no. 10 (2018): 639–41. http://dx.doi.org/10.1177/0883073818774960.

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An infantile spasm is a brief seizure type that is characteristic of West syndrome. Many infants present with infantile spasms between 3-12 months of age. Early diagnosis and proper treatment of patients with infantile spasms can lead to improved clinical outcomes. However, proper identification of these patients using claims data with validation has not been performed. The authors developed and tested several algorithms using claims data. Claims data consisted of using International Classification of Disease (ICD), Current Procedural Terminology (CPT), and prescription codes. Access to the cl
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Dissertations / Theses on the topic "Infantile Spams"

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Lux, Andrew Laurence. "The epidemiology and treatment of infantile spasms." Thesis, University of Bath, 2006. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425343.

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This thesis examines several aspects of the debate on the choice of best firstline treatment for infantile spasms. The first part of the thesis describes, analyses and interprets outcomes from the United Kingdom Infantile Spasms Study (UKISS), a multicentre randomised controlled trial that compares treatment with prednisolone or tetracosactide (hormonal treatments) against vigabatrin. This study was coordinated from the Bath Unit for Research in Paediatrics at the Royal United Hospital, Bath, and showed that the early primary clinical response, cessation of spasms, was significantly more likel
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Boutry, Kryza Nadia. "Étude moléculaire du syndrome des spasmes infantiles et des épilepsies familiales benignes." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10293.

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Werner, Klaus-Georg Erich. "Auditory processing in the syndrome of infantile spasms." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1445952/.

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The early onset epileptic encephalopathy of infantile spasms is frequently associated with acute cognitive regression, long-term learning disability and autistic spectrum disorder. Although there may be a structural basis to the epilepsy, it appears that seizure activity is directly implicated in the process associated with the above disabilities. There are strong indications of the crucial role of temporal lobe dysfunction in children within this and related epileptic regressions including the site of lesions in tuberous sclerosis and the EEG localisation in a later onset epileptic encephalop
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Nkinin, Stephenson. "GABA levels in Cerebrospinal fluid (CSF) as a Predictor for the Onset and Remission of Infantile Spasms." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1535702291258577.

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Maia, Maria Goretti Lima [UNIFESP]. "Evolução pós-Síndrome de West: aspectos clínicos e eletrográficos." Universidade Federal de São Paulo (UNIFESP), 2009. http://repositorio.unifesp.br/handle/11600/9608.

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Made available in DSpace on 2015-07-22T20:50:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-03-25<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>Objetivos: avaliar a evolução clínica e eletrencefalográfica em 28 pacientes que tiveram diagnóstico de Síndrome de West (SW). Métodos: estudo retrospectivo no qual foram incluídos pacientes que tiveram diagnóstico clínico e eletrográfico de SW e admitidos para seguimento no H
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Sienna, Julianna. "Retinal Origins of Vigabatrin Toxicity in Infantile Spasms." Thesis, 2011. http://hdl.handle.net/1807/31444.

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Vigabatrin (VGB) is an anti-epileptic drug used to treat children with Infantile Spasms (IS). The 3.0 flicker amplitude of the electroretinogram (ERG) is currently used to monitor visual function changes in infants on VGB. To find a more specific marker of permanent changes due to VGB, sedated ERGs were performed on 31 IS patients and 13 retinally normal controls to isolate components of the cone pathway. ERG growth curves, for each component, recorded from children with IS were generated using data recorded pre-VGB treatment and for controls. Only the cone off response (from Off bipolar cells
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Chen, Ying-Tzu, and 陳瑩慈. "EEG Analysis and Developmental Outcome following ACTH Treatment in Infantile Spasms." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/48482653933773564458.

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Tomé, Fernanda Manuela da Silva. "West Syndrome: from etiology to prognosis." Master's thesis, 2020. http://hdl.handle.net/10316/97741.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>The West syndrome is an epileptic encephalopathy in the child's first year of life, corresponding to 1.4% of the epileptic syndromes in pediatric age. It is characterized by the triad: 1) epileptic spasms, 2) hypsarrhythmic tracing on the electroencephalogram (EEG) and 3) neurodevelopment regression. It affects both sexes, with a higher incidence in males. The syndrome's etiology is diverse, including genetic, structural, metabolic, infectious, immunological and still unknown causes, which is why its diagno
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Prosser, Debra Olive. "Mitochondrial DNA (mtDNA) mutations in patients with suspected myoclonic epilepsy and ragged red muscle fibres (MERRF), Leigh syndrome (LS), and mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS)." Diss., 2001. http://hdl.handle.net/2263/30471.

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Mitochondrial disorders are considered to be the most common cause of metabolic abnormalities in the paediatric neurology population (Zeviani et al., 1996). These authors reported that the phenotypes observed in 25-30% of the paediatric patients in their neurology clinics were due to a mitochondrial aetiology. The genetic aetiology in an equivalently affected paediatric population in South Africa is currently unknown. This study investigated the possibility that reported mutations could account for the mitochondrial phenotypes observed in the South African population. It focussed on the most f
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Tzu-Ling, Liu, and 劉芝伶. "The Expression of Corticotropin-Releasing Hormone(CRH) and Cytokines in Patients of Infantile Spasm and in Neonatal Rats with Kainate-Induced Seizure." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/39419941947220771831.

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碩士<br>台北醫學院<br>細胞及分子生物研究所<br>86<br>Infantile spasm (IS), is a form of epilepsy specifically occurring at infant s tage, is refractory to conventional anticonvulsant treatment but is exceptiona lly sensitive to adrenocorticotropic hormone (ACTH) treatment. Corticotropin- releasing hormone (CRH), a major regulatory factor of ACTH secretion in pituit ary, has been implicated as an important neuro-hormone participating in seizur e generation particularly in early life of both human and animals. In human, excessive prod
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Books on the topic "Infantile Spams"

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Frost, James D., and Richard A. Hrachovy. Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8.

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Frost, James D. Infantile spasms: Diagnosis, management, and prognosis. Kluwer Academic Publishers, 2003.

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Ferry, Peggy C. Seizuredisorders in children. Lippincott, 1986.

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1920-, Kellaway Peter, ed. Diagnosis and management of neonatal seizures. Lippincott-Raven, 1998.

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William, Banner, and Wolf Ray A, eds. Seizure disorders in children. Lippincott, 1986.

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1960-, Schmitz Bettina, and Sander Thomas 1956-, eds. Juvenile myoclonic epilepsy: The Janz syndrome. Wrightson Biomedical Pub., 2000.

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G, Wasterlain Claude, Vert Paul, Institut national de la santé et de la recherche médicale (France), and National Institute of Child Health and Human Development (U.S.), eds. Neonatal seizures. Raven Press, 1990.

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(Editor), Olivier Dulac, Bernardo D. Bernardina (Editor), and Harry T. Chugani (Editor), eds. Infantile Spasms and West Syndrome. W.B. Saunders Company, 1994.

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Epilepsy, infantile spasms, and developmental encephalopathy. Academic, 2002.

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Jr, James D. Frost, and Richard A. Hrachovy. Infantile Spasms: Diagnosis, Management and Prognosis. Springer, 2003.

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Book chapters on the topic "Infantile Spams"

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Frost, James D., and Richard A. Hrachovy. "Introduction: Overview and Definitions." In Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8_1.

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Frost, James D., and Richard A. Hrachovy. "Pathophysiology." In Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8_10.

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Frost, James D., and Richard A. Hrachovy. "Treatment." In Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8_11.

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Frost, James D., and Richard A. Hrachovy. "Long-Term Outcome." In Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8_12.

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Frost, James D., and Richard A. Hrachovy. "History: 1841 – 1960." In Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8_2.

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Frost, James D., and Richard A. Hrachovy. "Epidemiology." In Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8_3.

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Frost, James D., and Richard A. Hrachovy. "Clinical Manifestations." In Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8_4.

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Frost, James D., and Richard A. Hrachovy. "Electroencephalography, Evoked Potentials, and Sleep." In Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8_5.

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Frost, James D., and Richard A. Hrachovy. "Neurodiagnostic Imaging." In Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8_6.

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Frost, James D., and Richard A. Hrachovy. "Differential Diagnosis and Related Syndromes." In Infantile Spasms. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0379-8_7.

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Conference papers on the topic "Infantile Spams"

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Zhang, Chuting, Gang Zhu, Wenbin Shi, Guang Yang, and Chien-Hung Yeh. "Contribution of Cross-Phase-Amplitude Coupling to Relapse in Infantile Epileptic Spasms Syndrome." In 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2024. https://doi.org/10.1109/embc53108.2024.10781620.

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Suzui, Ryosuke, Jun Natsume, Tatsuki Saito, and Koichi Fujiwara. "Long-short term memory autoencoder using delta with beta bands of EEG enables highly accurate prediction of seizure outcome in Infantile Epileptic Spasms Syndrome of unknown etiology." In 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2024. https://doi.org/10.1109/embc53108.2024.10782809.

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Smith, Rachel J., Daniel W. Shrey, Shaun A. Hussain, and Beth A. Lopour. "Quantitative Characteristics of Hypsarrhythmia in Infantile Spasms." In 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2018. http://dx.doi.org/10.1109/embc.2018.8512348.

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Jia, Feiyong, Lin Du, Huiyi Jiang, Honghua Li, and Chunbo Niu. "Betahistine is effective in combatting spasms in NMDA-inducing infantile spasms rat model." In 2011 International Conference on Human Health and Biomedical Engineering (HHBE). IEEE, 2011. http://dx.doi.org/10.1109/hhbe.2011.6027923.

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de Azeredo, Saulo Bueno, Eduarda Vogel Wollmeister, Lucas Lizot Pozzobon, et al. "ACTH versus corticosteroid in infantile spasms: a literature review." In SBN Conference 2022. Thieme Revinter Publicações Ltda., 2023. http://dx.doi.org/10.1055/s-0043-1774436.

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Moura, Ludmila Sandy Alves, André Taumaturgo Cavalcanti Arruda, and Mário Luciano de Melo Silva Júnior. "Case Report of Tuberous Sclerosis with early West Syndrome." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.542.

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Context: We present a patient diagnosed with Tuberous Sclerosis (TS) who developed West Syndrome (WS) early on. Early diagnosis of TS is important for genetic counseling and WS requires early intervention to avoid neurodevelopmental deficits. Case report: Y.S.L.C., female, 45 days old, presented cardiac rhabdomyoma and 9 hypomelanotic lesions, being diagnosed with TS. At 2 months old, she presented epileptic seizures of flexion spasms, which progressed in 1 week to neuropsychomotor development (NP) regression and hypsarrhythmia. She was diagnosed with WS and treated with vigabatrin. There was
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Traitruengsakul, Supachan, Laurie E. Seltzer, Alex R. Paciorkowski, and Behnaz Ghoraani. "Automatic localization of epileptic spikes in eegs of children with infantile spasms." In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2015. http://dx.doi.org/10.1109/embc.2015.7319807.

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Rosario, Malcom, Alexander Bolufer, and Vikram Prakash. "Efficacy of Vigabatrin as Treatment for Seizures in Children Without Infantile Spasms (P4-9.009)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000203514.

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Shrock, Christine, Margaret Savage, Lauren Sham, et al. "Diagnosing Infantile Epileptic Spasms: Can Smartphone Videos Replace EEG in Resource-limited Settings? (P13-1.001)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000204228.

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Kalser, J., B. Plecko, F. Giuliano, and B. K. Bölsterli. "A Case of Vitamin-B6-Dependent Disorder Presenting with Abnormal Eye–Head Movements and Infantile Spasms without Hypsarrhythmia." In Abstracts of the 48th Annual Meeting of the SENP (Société Européenne De Neurologie Pédiatrique). Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1746216.

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