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Relevant bibliographies by topics / Infants (Newborn)

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Academic literature on the topic 'Infants (Newborn)'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2024

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Journal articles on the topic "Infants (Newborn)"

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Lis-Kuberka, Jolanta, and Magdalena Orczyk-Pawiłowicz. "Sialylated Oligosaccharides and Glycoconjugates of Human Milk. The Impact on Infant and Newborn Protection, Development and Well-Being." Nutrients 11, no. 2 (February 1, 2019): 306. http://dx.doi.org/10.3390/nu11020306.

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Human milk not only has nutritional value, but also provides a wide range of biologically active molecules, which are adapted to meet the needs of newborns and infants. Mother’s milk is a source of sialylated oligosaccharides and glycans that are attached to proteins and lipids, whose concentrations and composition are unique. Sialylated human milk glycoconjugates and oligosaccharides enrich the newborn immature immune system and are crucial for their proper development and well-being. Some of the milk sialylated oligosaccharide structures can locally exert biologically active effects in the newborn’s and infant’s gut. Sialylated molecules of human milk can be recognized and bound by sialic acid-dependent pathogens and inhibit their adhesion to the epithelial cells of newborns and infants. A small amount of intact sialylated oligosaccharides can be absorbed from the intestine and remain in the newborn’s circulation in concentrations high enough to modulate the immunological system at the cellular level and facilitate proper brain development during infancy. Conclusion: The review summarizes the current state of knowledge on sialylated human milk oligosaccharides and glycoconjugates, discusses the significance of sialylated structures of human milk in newborn protection and development, and presents the advantages of human milk over infant formula.

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Purdy, Isabell. "Newborn Auditory Follow-Up." Neonatal Network 19, no. 2 (March 2000): 25–33. http://dx.doi.org/10.1891/0730-0832.19.2.25.

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Because hearing is a key component in the infant’s development of speech, language, and cognition, early detection of infant hearing loss is critically important. The routine evaluation of hearing should include the identification of parental concerns regarding infant hearing as well as the assessment and diagnosis of infants with potential hearing impairment. Identification of hearing loss should be followed by early interventions to prevent developmental delays. This article promotes universal screening of newborn hearing. The article also provides a review of the embryogenesis of hearing and includes a breakdown of risks for hearing loss, recommendations for auditory testing, and suggestions for follow-up, early intervention, and support for families of infants with hearing impairment.

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Windarti, Siti Wahyu, and Ahmad Suryawan. "Effectiveness of The Newborn Behavioral Observation (NBO) System in Improving Mother and Infant Interaction." Folia Medica Indonesiana 57, no. 2 (June 1, 2021): 90. http://dx.doi.org/10.20473/fmi.v57i2.21558.

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The interaction of mother and infant is a fundamental basis for the development of the infant. It can also determine the success of the baby in the future. About 4 out of 10 infants experience problems interacting with their parents. The NBO system was created to sensitize parents on their infant’s competencies to help them understand their infant’s behavior, and promote positive interactions between parents and their new infant. This study aimed to evaluate the effectiveness of the NBO system to improve mother-infant interactions and find out the mothers’ knowledge about their infant’s behavior when participating in this observation. This study was a cross-sectional study consisting of all the newborns and their mothers admitted to the Dr. Soetomo General Academic Hospital Surabaya from May 2019 to January 2020 who met the inclusion criteria. Mothers and infants participated in the NBO within 1-3 days after delivering their infants and one month postpartum for the second NBO. The NBO was carried out with 35 mothers and infants. The mothers’ age was on average 28.5±5.98 years old, multiparous mothers accounted for 71.4%, most infants were male (65.7%), the median gestational age was 38 weeks with the median birth weight 2900 grams. The median score of mothers’ knowledge about their infants before the NBO session was 2 (1-6). After the session, these median scores increased to 7 (5–10) significantly (p<0.001). The NBO system was significant to strengthen mother-infant interaction and increased the mothers’ knowledge about their infants’ behavior.

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DuPont, Herbert, and Madeleine Salge. "The Importance of a Healthy Microbiome in Pregnancy and Infancy and Microbiota Treatment to Reverse Dysbiosis for Improved Health." Antibiotics 12, no. 11 (November 11, 2023): 1617. http://dx.doi.org/10.3390/antibiotics12111617.

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Background: The microbiome of newborn infants during the first 1000 days, influenced early on by their mothers’ microbiome health, mode of delivery and breast feeding, orchestrates the education and programming of the infant’s immune system and determines in large part the general health of the infant for years. Methods: PubMed was reviewed for maternal infant microbiome health and microbiota therapy in this setting with prebiotics, probiotics, vaginal seeding and fecal microbiota transplantation (FMT). Results: A healthy nonobese mother, vaginal delivery and strict breast feeding contribute to microbiome health in a newborn and young infant. With reduced microbiome diversity (dysbiosis) during pregnancy, cesarean delivery, prematurity, and formula feeding contribute to dysbiosis in the newborn. Microbiota therapy is an important approach to repair dysbiosis in pregnant women and their infants. Currently available probiotics can have favorable metabolic effects on mothers and infants, but these effects are variable. In research settings, reversal of infant dysbiosis can be achieved via vaginal seeding or FMT. Next generation probiotics in development should replace current probiotics and FMT. Conclusions: The most critical phase of human microbiome development is in the first 2–3 years of life. Preventing and treating dysbiosis during pregnancy and early life can have a profound effect on an infant’s later health.

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Lobo, Renilda Shanthi, Theresa Leonilda Mendonca, and Seema S. Chavan. "Maternal directed interventions of preterm newborn on strengthening mother- newborn interaction in NICU: A systematic review." IP Journal of Paediatrics and Nursing Science 6, no. 4 (December 15, 2023): 130–35. http://dx.doi.org/10.18231/j.ijpns.2023.023.

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The main factor contributing to neonatal fatalities globally is preterm birth Maternal participation in the care of preemies in the NICU can be challenging for mothers to strengthen the bond between them. The objective of the literature review was to appraise the effectiveness of maternal-directed interventions of preterm newborns on strengthening mother-newborn interaction in NICU, identify which tools are most frequently used, and report on outcomes of strengthening mother-newborn interaction in NICU.We conducted a PRISMA-compliant Meticulous search for articles indexed in the databasesPubMed, Psyc INFO, Web of Science, and CINAHL using disparate combinations of keywords comprising “maternal directed interventions’’ AND “preterm newborn’’ OR “strengthening’’ AND “mother- newborn interaction” were used to review in the databases. Five empirical studies were identified, massage including Auditory, Tactile, Visual, and Vestibular was linked to a faster symptom reduction of depression, ATVV have significant implications for mom and their premature babies, especially during the initial six months of life. At day 14 (=45.66, p<0.01), there were noticeable differences between groups as the suction pressure rose linearly over time. The mean weight, height, and head circumference of preterm babies who received the 2-week massage intervention were higher (F=41.151, 6.621, and 24.158, respectively; p<0.001). Breastfeeding habits among mothers of preterm infants are improved by the kangaroo mother's nursing on the infant's growth, neurological development, and reduction of morbidities related to preterm infants. Maternal interventions support infants from birth through early life to improve infant health, develop newly acquired abilities, reduce developmental issues, promote adaptive parenting and strengthen the mother-newborn bond.

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V R Selvaambigai. "A Study to Assess the Impact of Pathological Jaundice on Development during Early Childhood at Selected Hospitals, Puducherry, India." International Journal of Nursing Care 7, no. 1 (January 21, 2019): 93–98. http://dx.doi.org/10.37506/ijonc.v7i1.7667.

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Infants are important vulnerable groups in the segment of population and they are the determinants of health of nation. The future of the country depends on the care given to children. Jaundice is considered pathologic if it presents within the first 24 hours after birth, the total serum bilirubin level rises by more than 5 mg per dL (86 mol per L) per day or is higher than 17 mg per dL (290 mol per L), or an infant has signs and symptoms suggestive of serious illness. The present study aimed to assess the development among infants affected with pathological jaundice at selected hospital in puducherry. A descriptive research design was used and the study was carried out, 300 infants affected with pathological jaundice during newborn life were selected as the study sample using convenient sampling technique. The tools used for the data collection included newborn assessment tool, ages and stages questionnaire. Ages and stages questionnaire is a standardized questionnaire used worldwide to assess the development of children at all level of ages. Newborns with pathological jaundice were assessed for their growth. The newborns were followed during their regular visit to well-baby clinic, there development were assessed at 1 months (early infancy )and again at 12 months(late infancy) .On association between the early and late infants development, it was found that there was improvement in development between them which stated that there was impact of pathological jaundice on the development during early infancy whereas during late infancy they caught with the normal development showing improvement in overall domains. As per the statistical result, the calculated chisquare value was significant at 0.01 level (p<0.001).

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MERCHANT, NAZAKAT, and DENIS AZZOPARDI. "HYPOXIC ISCHAEMIC ENCEPHALOPATHY IN NEWBORN INFANTS." Fetal and Maternal Medicine Review 21, no. 3 (May 19, 2010): 242–62. http://dx.doi.org/10.1017/s0965539510000069.

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Neonatal encephalopathy has been defined as “a clinically defined syndrome of disturbed neurological function in the earliest days of life in the term infant, manifested by difficulty with initiating and maintaining respiration, depression of tone and reflexes, sub normal level of consciousness and often seizures”. It occurs in about 2–3 per 1000 births in developed countries. In developing countries, neonatal encephalopathy accounts for the largest number of deaths in infancy and childhood – approximately 1 million per year worldwide. Neonatal encephalopathy is associated with significant morbidity and mortality and is an important predictor of long term neurodevelopmental disability in near- and full-term newborn infants. Fifteen to 20 percent of infants with neonatal encephalopathy die in the neonatal period, and a further 25 percent have permanent neurologic deficits.

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Blaga, Ligia, Camelia Vidra, Gabriela Abrudan, Adriana Ciubotariu, Mircea Margescu, Alina Grama, and Tudor Lucian Pop. "Risk factors for neonatal cholestasis in small gestational age infants: case report and literature review." Newborn Reviews & Research 2, no. 1 (March 31, 2024): 21–25. http://dx.doi.org/10.37897/newborn.2024.1.4.

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Cholestatic jaundice, defined as conjugated bilirubin levels higher than 1 mg/dl, is a bile formation and excretion disturbance. Its incidence is estimated at 1 case in 2500 live births, being 100-200 times higher in preterm infants less than 28 weeks gestational age. It occurs in biliary atresia, infectious diseases, endocrine and inherited metabolic diseases, Alagille Syndrome, preterm and intrauterine growth-restricted newborns, lack of enteral feeding, and is more frequent in male gender. It is a frequent complication of parenteral nutrition. In preterm and small for gestational age (SGA) infants, the etiology of cholestasis is multifactorial. Early diagnosis enables early therapeutic intervention. We report the case of an SGA male preterm infant. He was born by C-section for fetal distress at 30 weeks gestational age with an 800 g birth weight. He developed mild respiratory distress, hypoglycemia, meconium ileus, and early cholestasis. Complex hematological, serological, and immunological tests were carried out; ultrasound evaluations were performed. The final diagnosis was cholestasis of multifactorial etiology in a preterm infant with severe intrauterine growth restriction (IUGR). Treatment with ursodeoxycholic acid was started. Three months later, the transaminases, bilirubin, gammaglutamyl transferase (GGT), and alkaline phosphatase (ALP) triglycerides returned to normal. Conclusion. Cholestasis in SGA infants is a severe condition potentially associated with life-threatening complications, requiring complex diagnostic evaluation.

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Walsh, Heidi A. "Newborn Male Circumcision." Narrative Inquiry in Bioethics 13, no. 2 (June 2023): 65–69. http://dx.doi.org/10.1353/nib.2023.a909656.

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Abstract: This symposium includes twelve personal narratives from parents about making the decision whether to circumcise their infant male children. The authors of the narratives include five fathers and seven mothers. Nine of the 12 parent authors opted to circumcise their infant sons, though the reasons they stated for doing so varied. Most of the parent authors relied on cultural or social beliefs, religious guidance, or a desire for sameness with the infant's father. Parents who didn't circumcise their male infants discuss their convictions about autonomy, bodily rights, and the medical benefits of circumcision versus the harm or pain caused by the procedure. The symposium includes four expert commentaries on the narratives that are informed and enriched by the commentators' expertise in pediatric bioethics, healthcare ethics, gender studies, Jewish law and tradition, and the medical and surgical techniques of circumcision.

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Urquia, ML, TA Stukel, K. Fung, RH Glazier, and JG Ray. "Estimating gestational age at birth: a population-based derivation-validation study." Chronic Diseases and Injuries in Canada 31, no. 3 (June 2011): 103–8. http://dx.doi.org/10.24095/hpcdp.31.3.04.

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Introduction Information on newborn gestational age (GA) is essential in research on perinatal and infant health, but it is not always available from administrative databases. We developed and validated a GA prediction model for singleton births for use in epidemiological studies. Methods Derivation of estimated GA was calculated based on 130 328 newborn infants born in Ontario hospitals between 2007 and 2009, using linear regression analysis, with several infant and maternal characteristics as the predictor (independent) variables. The model was validated in a separate sample of 130 329 newborns. Results The discriminative ability of the linear model based on infant birth weight and sex was reasonably approximate for infants born before the 37th week of gestation (r2 = 0.67; 95% CI: 0.65–0.68), but not for term births (37–42 weeks; r2 = 0.12; 95% CI: 0.12–0.13). Adding other infant and maternal characteristics did not improve the model discrimination. Conclusion Newborn gestational age before 37 weeks can be reasonably approximated using locally available data on birth weight and sex.

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Dissertations / Theses on the topic "Infants (Newborn)"

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Wan, Shek-kong Thomas. "Neutrophil function tests in Chinese newborn infants." Hong Kong : University of Hong Kong, 1991. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13186292.

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Au, Man-tak. "A study on the growth profile and factors affecting the rate of growth of new born babies in Hong Kong." [Hong Kong] : University of Hong Kong, 1991. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13064915.

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溫錫剛 and Shek-kong Thomas Wan. "Neutrophil function tests in Chinese newborn infants." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1991. http://hub.hku.hk/bib/B43893363.

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Chukwudifu, Chibuikem Nwabueze, and Leila Mwakinpunda. "Course of aspiration syndrome in newborn infants." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/41241.

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Aspiration syndrome of newborn children is one of reasons of development of the decompensated respiratory insufficiency that requires realization of artificial ventilation of lungs (ALV). In the department of intensive therapy new-born (ICU) of the Sumy regional child's clinical hospital for period 2009-2014 acted 1179 babies, 200 (17%) from them were hospitalized with a diagnosis neonatal aspiration.

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Tang, Mei-po. "Weight gain and methods of feeding a retrospective cohort study of the Hong Kong Chinese infants /." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31972214.

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Horne, Pamela. "The effects of glucose on the memory and attention of newborn human infants /." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=30668.

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The objective of this randomized, double-blind, placebo-controlled trial was to determine whether glucose enhanced memory for a repeated auditory stimulus in human newborns. Infants consumed water or glucose (2-g/kg) solution. Memory test phases were: Orientation (turning towards the stimulus); Habituation (not turning towards), indicating familiarity; Delay (100 seconds); Spontaneous Recovery (stimulus representation: not turning towards indicates remembering, while turning towards indicates forgetting), and Novelty (turning towards a different word confirms wakefulness). Decreased head-turning towards during Spontaneous Recovery indicates enhanced memory. Blood glucose levels were measured after testing.
"Glucose" infants had higher blood glucose levels than "water" infants (p < 0.001). "Glucose" infants had significantly decreased turns towards during Spontaneous Recovery compared to "water" infants (p = 0.008), indicating memory enhancement.
Therefore, glucose specifically enhances memory for a repeated auditory stimulus in newborn humans. Elevating blood glucose levels by approximately 2 mmol/L appears to be sufficient for memory enhancement in healthy newborns.

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Marshall, Timothy R. "Holding and rocking the full-term neonate: the immediate and residual effects on behavioral state and heart rate." Diss., Virginia Polytechnic Institute and State University, 1989. http://hdl.handle.net/10919/54237.

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This study explored infants' immediate and residual responses to holding and rocking, and how these responses relate to previously proposed mechanisms to explain long term benefits found when infants are repeatedly exposed to tactile and vestibular stimulation. This form of stimulation has been proposed to increase infants' ability to control and organize l) their behavioral state, 2) their arousal and autonomic functioning, or 3) that there is no clear relationship between immediate responses and long term benefits. Behavioral state and heart rate were collected on 40 infants who were randomly assigned to either a control group where infants were briefly repositioned twice but otherwise lay undisturbed for 90 minutes or an experimental group where infants were held and rocked for 30 minutes during the middle of a 90-minute observation. Results of analyses showed that, when infants were held and rocked they 1) displayed a lower Heart Rate Mean and Standard Deviation, 2) displayed a lower Mean Heart Rate During Active Sleep, 3) spent less time in a FussCry State, 3) were less likely to cry continuously, and 4) displayed nominally Smoother State Transitions and greater Stability Within States. Following the cessation of the rocking stimulus infants in the Experimental Group l) displayed a lower Mean Heart Rate, 2) displayed a lower Mean Heart Rate while in a Quiet Alert State, 3) were more likely to spend some time in a Quiet Sleep State, and 4) were less likely to cry continuously. In addition, all infants displayed Smoother State Transitions and greater Stability Within States during the first 30 minutes than during the final 30 minutes of the observation. Finally, across the 90-minute observation, the infants who were not rocked spent progressively more time in a Quiet Alert State, whereas infants who were rocked spent less time in a Quiet Alert State. The results were the most consistent with the hypothesis that the mechanism leading to both the immediate and residual effects of the stimulation was an increase in control and organization of infants’ arousal and autonomic functioning.
Ph. D.

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Samson, Gregory Raymond. "An immune study of newborn infants with congenital syphilis." Thesis, University of Cape Town, 1995. http://hdl.handle.net/11427/26182.

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Pegg, Judith E. "Young infants demonstrate a preference for infant directed talk." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/28997.

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This research was designed to assess 7-week-old infants' preference for infant directed and adult directed talk. (IDT and ADT) using the infant controlled habituation/dishabituation looking procedure. Infants were presented with short audio recordings of either a female or a male speaking in IDT during habituation and ADT during dishabituation or the reverse. In the control conditions, the stimulus did not change. Infants demonstrated preference for IDT over ADT in both male and female speaker conditions. They also demonstrated preference for the female speaker used in this study over the male speaker. Interactions among the dependent variables (first three looks), and the independent variables (infant gender, and style of speaking as well as infant gender, and speaker gender), suggest that the preference might not be as robust as the preference found in infants over 4 months. Evidence for discrimination between IDT and ADT was inferred from the between group demonstration of preference, but no evidence of within infant discrimination was found. Because the evidence suggests that 7-week-old infants demonstrate weaker preference for IDT over ADT than do infants of 4 months, it is assumed that infant preferences follow a developmental sequence. Thus, it is possible that developing preferences are influenced by experiential factors.
Arts, Faculty of
Psychology, Department of
Graduate

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de, la Cruz-Schmedel Dorothy. "Neonate psychophysiological responses to ambient features of the neonatal intensive care unit." Scholarly Commons, 1989. https://scholarlycommons.pacific.edu/uop_etds/549.

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Hospital treatment environments have become a major concern in recent years. Noise and illumination are potential stress sources in hospitals. The purpose ofthis study was to examine the effects of hospital noise levels and ambient illumination on newborn infants (neonates). Noise levels and lighting were varied and the effect upon neonatal heart rate, respiration rate, blood pressure, and oxygen consumption were measured. These measures are sensitive tosympathetic nervous system reactivity such as that brought about by stressful environments. In addition, noise and lighting levels were measured to determine if differences existed across conditions. Psychophysiological responses to various noise and lighting levels varied within and across neonates with some changes in the expected direction. Some unexpected results of Quiet Time were noted among neonatal intensive care staff and hospital personnel.

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Books on the topic "Infants (Newborn)"

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B, Johnston Peter G., ed. The newborn child. 6th ed. Edinburgh: Churchill Livingstone, 1987.

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Vulliamy, David G. The newborn child. 6th ed. Edinburgh: Churchill Livingstone, 1987.

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Schatz, Howard. Newborn. Edited by Ornstein Beverly J. San Francisco: Chronicle Books, 1996.

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Prem, Puri, ed. Newborn surgery. 2nd ed. London: Arnold, 2003.

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Krauss, Michael. Your newborn baby: Everything you need to know. New York, NY: Warner Books, 1988.

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Balfour-Lynn, I. M. Practical management of the newborn. 5th ed. Oxford: Blackwell Scientific Publications, 1993.

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Klaus, Marshall H. Your amazing newborn. Reading, Mass: Perseus Books, 1998.

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Dulock, Helen L. Hypoglycemia in the newborn. 2nd ed. White Plains, NY: March of Dimes Birth Defects Foundation, 1990.

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Smith, Timothy. Miracle birth stories of very premature babies: Little thumbs up! Westport, Conn: Bergin & Garvey, 1999.

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Yu, Victor Y. H. Respiratory disorders in the newborn. Edinburgh: Churchill Livingstone, 1986.

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Book chapters on the topic "Infants (Newborn)"

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Lipsitt, Lewis P. "The Newborn as Informant." In Infants at Risk, 1–22. London: Routledge, 2021. http://dx.doi.org/10.4324/9781003171447-1.

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Affleck, Glenn, Howard Tennen, and Jonelle Rowe. "Mothers’ Remembrances of Newborn Intensive Care." In Infants in Crisis, 99–115. New York, NY: Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4612-3050-2_8.

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Naga, Osama. "Fetus and Newborn Infants (Neonatology)." In Pediatric Board Study Guide, 119–48. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-10115-6_8.

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Kaleem, Musa, and Srikrishna Harave. "Chest radiology in infants." In Respiratory Diseases of the Newborn Infant, 301–19. Sheffield, United Kingdom: European Respiratory Society, 2021. http://dx.doi.org/10.1183/2312508x.10015120.

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Jones, Caroline B., and Melonie Johns. "Pulmonary hypertension in preterm infants." In Respiratory Diseases of the Newborn Infant, 89–103. Sheffield, United Kingdom: European Respiratory Society, 2021. http://dx.doi.org/10.1183/2312508x.10013920.

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Hyman, A. I. "History of Resuscitation of Newborn Infants." In Anaesthesia, 141–44. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-69636-7_31.

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Narayan, Omendra, Aditi Sinha, Rasha Ibrahim, Shashank Kadam, and Elizabeth Hill. "Sleep physiology and disorders in newborn infants." In Respiratory Diseases of the Newborn Infant, 273–86. Sheffield, United Kingdom: European Respiratory Society, 2021. http://dx.doi.org/10.1183/2312508x.10014920.

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Papoušek, Hanuš, and Mechthild Papoušek. "Ontogeny of Social Interactions in Newborn Infants." In Neurobiology of Early Infant Behaviour, 217–25. London: Macmillan Education UK, 1989. http://dx.doi.org/10.1007/978-1-349-10735-3_20.

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Svenningsen, N. W. "Amplitude Integrated EEG Monitoring in Newborn Infants." In Neurobiology of Early Infant Behaviour, 357–65. London: Macmillan Education UK, 1989. http://dx.doi.org/10.1007/978-1-349-10735-3_33.

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Bishop, Ruth F., D. J. S. Cameron, G. L. Barnes, I. H. Holmes, and B. J. Ruck. "The Aetiology of Diarrhoea in Newborn Infants." In Novartis Foundation Symposia, 223–36. Chichester, UK: John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470720240.ch13.

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Conference papers on the topic "Infants (Newborn)"

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Faul, S. "Computer-aided seizure detection in newborn infants." In Irish Signals and Systems Conference 2004. IEE, 2004. http://dx.doi.org/10.1049/cp:20040580.

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Manco-Johnson, M. J., T. C. Abshire, and L. J. Jacobson. "FREQUENCY AND IMPLICATIONS OF SEVERE NEONATAL PROTEIN C DEFICIENCY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643609.

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The newborn infant has a physiologically low level of protein C which rises very slowly in postnatal life. The frequency and significance of severe neonatal protein C deficiency has not been reported. In this study, protein C levels were measured in 110 newborn infants at the time of birth using functional (amidolytic, Cact) and immunologic (Laurell rocket, Cag) assays. The protein C levels were compared with a marker of thrombin activation (D-dimer fragment of fibrin, +D-D) and infants were subsequently followed for signs and symptoms of thrombosis. Results are summarized below (protein C levels are expressed as U/ml).Thirteen infants had protein C levels compatible with the homozygous deficiency state. Extremely low levels of protein C (<0.20 U/ml) were not found in well term infants and were rarely noted in stable preterm infants. D-D were infrequently present and no thrombosis occurred. Near term infants born with fetal distress frequently showed +D-D but rarely demonstrated extremely low levels of protein C. None of these infants required indwelling arterial catheters and no thromboses occurred. Preterm infants with severe respiratory distress showed lower protein C levels at birth (p <0.01). Although 71% had +D-D, thromboses in these infants were all related to invasive catheterizations. In contrast, the study population of twins demonstrated a high frequency of severe protein C deficiency with negative D-D and frequent thromboses, three of which occurred in the absence of instrumentation. In summary, severe protein C deficiency and thrombin activation are common in sick preterm infants with the risk of thrombosis increased by intravascular catheterization. In contrast, twins with severe protein C deficiency may manifest a thrombotic risk which is independent of thrombin activation or catheterization.

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YAMADA, K., T. MEGURO, A. SHIRAHATA, T. NAKAMURA, and A. ASAKURA. "EFFECTS OF VITAMIN K ON VITAMIN K DEPENDENT PROTEINS IN NEWBORN INFANTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644264.

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Plasma levels of vitamin K (VK) and VK dependent proteins ( factor E, factor VH, factor X, protein C and osteocalcin)were determined before and after VK administration to 22 newborn infants. Vitamin K2 syrup ( 2 mg/kg of body weight ) was orally administered to 9 healthy premature, 11 high risk and 2 VK deficient infants under 3 days of age. VK families extracted from plasma were separated by high performance liquid chromatography using a Cosmosil 5 Ci8 column, and separated VK families were detected by a fluorometry after their reaction with ethanolic sodium borohydride in a reaction coil connected by one-line to a chromatographic column. Total activity of factor E, factor VE and factor X was assayed by a Normotest ( Nyegaard ), and protein C was measured by protac/APTT and protac/chromogenic substrate ( S-2366 ) functional assay system ( American Diagnostica ). Osteocalcin levels were assayed by using of a RIA method before and after the absorption of plasma by hydroxyapatite.After VK administration, plasma VK2 ( menaquinone-4 ) content increased from levels less than 0.012yg/ml to levels between 15.9 and 70.9μg/ml, excluding one case in whom plasma VK was not detected after VK administration. Compared with Normotest values and osteocalcin levels of age-matched healthy newborn infants treated without VK, premature, high risk and VK deficient infant levels significantly increased after 24 hrs and after 7 days of VK administration. No correlation was seen between the increase of plasma VK contents and the increase of Normotest values after VK administration. On the other hand, no significant increase of protein C assayed by both methods was observed in healthy premature and high risk infants after VK administration.These results indicate that the change of protein C after VK treatment is different from that of factor II, VII, X and osteocalcin.

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Manfredi, C., L. Bocchi, S. Orlandi, M. Calisti, L. Spaccaterra, and G. P. Donzelli. "Non-invasive distress evaluation in preterm newborn infants." In 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2008. http://dx.doi.org/10.1109/iembs.2008.4649811.

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Syuadzah, Rahmi, Hari Wahyu Nugroho, and Safitri Tia Tampy. "Association between Maternal Weight and A Newborn Weight in Surakarta, Central Java." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.03.12.

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ABSTRACT Background: In Indonesia, nutrition is still the 5 biggest problem for mothers and children. Nutrition in the mother during pregnancy will affect the nutrition the infant gets while in the womb. Nutrition in children is very important in the first 1000 days of life because it will affect the growth and development of the infant. One way to assess the nutritional adequacy of new born is by measuring the infant’s weight at birth. This study aimed to determine the relationship between maternal weight and birth weight. Subjects and Method: This was a cross sectional study conducted at Pajang Community Health Center, Surakarta, Central Java. The study subjects were all mothers and infants whose birth weight were measured during February to March 2020. The dependent variable in this study was maternal weight. The independent variable was birth weight. The data were taken from the medical records of the Pajang Community Health Center. The data were analyzed using logistic regression test Results: Maternal weight below the normal weight had tendency to produce babies with less weight than pregnant women with normal maternal weight (OR= 55.00; p<0.001), and it was statistically significant. Conclusion: There is a significant relationship between maternal weight of pregnant women and birth weight Keywords: maternal weight, birth weight Correspondence: Rahmi Syuadzah. Pediatric Research Center (PRC), Department of Child Health, Dr. Moewardi Hospital, Surakarta. Jl. Colonel Sutarto, Jebres, Kec. Jebres, Surakarta City, Central Java 57126. Email: Rahmi_syuadzah@yahoo.com. Mobile: 082144806405 DOI: https://doi.org/10.26911/the7thicph.03.12

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Andrew, M., B. A. Paes, R. A. Milner, P. J. Powers, M. Johnston, and V. Castle. "THE POSTNATAL DEVELOPMENT OF THE COAGULATION SYSTEM IN THE PREMATURE INFANT." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643606.

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A cohort study was performed to determine the postnatal development of the coagulation system in the “healthy” premature infant. Mothers were approached for consent and a total of 132 premature infants were entered into the study. The group consisted of 64 infants with gestational ages of 34-36 weeks (prem 1) and 68 infants whose gestational age was 33 weeks or less (prem 2). Demographic information and a 2 ml blood sample were obtained on days 1, 5, 30, 90, and 180. Plasma was fractionated and stored at −70°C for batch assaying of the following tests: screening tests, PT, APTT; factor assays (biologic (B)); fibrinogen, II, V, VII, VIII:C, IX, X, XI, XII, prekallikrein, high molecular weight kininogen, XIII (immunologic (I)); inhibitors (I), antithrombin III, aα2-antiplasmin, α2-macroglobulin, α-anti-trypsin, Cl esterase inhibitor, protein C, protein S, and the fibrinolytic system (B); plasminogen. We have previously reported an identical study for 118 full term infants. The large number of premature and full term infants studied at varying time points allowed us to determine the following: 1) coagulation tests vary with the gestational age and postnatal age of the infant; 2) each factor has a unique postnatal pattern of maturation; 3) near adult values are achieved by 6 months of age; 4) premature infants have a more rapid postnatal development of the coagulation system compared to the full term infant; and 5) the range of reference values for two age groups of premature infants has been established for each of the assays. These reference values will provide a basis for future investigation of specific hemorrhagic and thrombotic problems in the newborn infant.

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Gu, Brian, Malvi Hemani, Barbara Kim, Angelica Herrera, Eun Yong Kim, Hyun Soo Jang, Megan Lamberti, and Anne Pigula. "Neonatal Resuscitation: A Global Perspective." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14353.

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Approximately 904,000 newborns die of breathing complications, or birth asphyxia, each year[1]. It is estimated that 30% of these deaths could be prevented[2]; however, healthcare workers in developing nations often lack the training, skills, or equipment necessary to properly resuscitate these infants. For this reason, child mortality is disproportionally clustered in low-resource locations in which the current standard of care is ineffective. The bag-valve mask resuscitator (or BVM) is the recommended treatment for a newborn who is not breathing properly.

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SHEN, M. C., S. H. CHEN, and K. S. LIN. "TWO CASES OF NEONATAL PURPURA FULMINANS HOMOZYGOUS FOR PROTEIN C DEFICIENCY IN A CHINESE FAMILY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644308.

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Protein C (PC) deficiency associated with hereditary venous thromboembolic disease was first reported in 1981 and is inherited as an autosomal dominant disorder. The prevalence of heterozygous PC deficiency is estimated to be 1 to 4% in venous thrombotic diseases. The homozygous PC deficiency is even rare, and has been reported in only about 10 families througout the world. It usually presents in newborn infants as purpura fulminans or severe thrombotic disease. We herein report two newborn brothers in a Chinese family, who manifested with purpura fulminans soon after birth and died at age of 21 days and 27 days respectively. Vitamin K was administered to the second baby after birth. Both parents are not consanguineous and there were no family histories of thromboembolism on paternal and maternal sides. Blood sample was not available for specific studies in the first baby. PC antigen level by electroimmunoassay was <6% in the second baby and 49% and 60% respectively in their mother and father. Antithrombin III activity by amidolytic method was 49% in the second baby, and 90% and 97% respectively in their mother and father. Vitamin K-dependent coagulation factors and factor V were within the expected range for a newborn. Factor VIII and fibrinogen level were notably decreased. Autopsy findings of the two newborns demonstrated the similar pictures characterized by fibrin thrombi in blood vessels causing extensive hemorrhagic infarts of skin, lung, liver, kidneys, testis, urinary bladder, esophagus and brain. Our Data indicate that neonatal purpura fulminans can be familial and caused by severe homozygous PC deficiency.

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Partridge, Tom J., David E. Morris, Roger A. Light, Andrew Leslie, Don Sharkey, John A. Crowe, and Donal S. McNally. "Finding Comfortable Routes for Ambulance Transfers of Newborn Infants*." In 2020 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) in conjunction with the 43rd Annual Conference of the Canadian Medical and Biological Engineering Society. IEEE, 2020. http://dx.doi.org/10.1109/embc44109.2020.9175873.

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Dassios, Theodore, Ourania Kaltsogianni, and Anne Greenough. "Determinants of pulmonary dead space in ventilated newborn infants." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2066.

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Reports on the topic "Infants (Newborn)"

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W, Nedra, Laura B. Strange, Sara M. Kennedy, Katrina D. Burson, and Gina L. Kilpatrick. Completeness of Prenatal Records in Community Hospital Charts. RTI Press, February 2018. http://dx.doi.org/10.3768/rtipress.2018.rr.0032.1802.

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We describe the completeness of prenatal data in maternal delivery records and the prevalence of selected medical conditions and complications among patients delivering at community hospitals around Atlanta, Georgia. Medical charts for 199 maternal-infant dyads (99 infants in normal newborn nurseries and 104 infants in newborn intensive care nurseries) were identified by medical records staff at 9 hospitals and abstracted on site. Ninety-eight percent of hospital charts included prenatal records, but over 20 percent were missing results for common laboratory tests and prenatal procedures. Forty-nine percent of women had a pre-existing medical condition, 64 percent had a prenatal complication, and 63 percent had a labor or delivery complication. Missing prenatal information limits the usefulness of these records for research and may result in unnecessary tests or procedures or inappropriate medical care.

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Shellhaas, Renée A., Janet S. Soul, Taeun Chang, Courtney J. Wusthoff, Catherine J. Chu, Shavonne L. Massey, Nicholas S. Abend, et al. Looking at the Effect of Treatment Duration for Newborn Infants Who Have Seizures. Patient-Centered Outcomes Research Institute (PCORI), July 2021. http://dx.doi.org/10.25302/07.2021.cer.150731187.

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Ovelman, Colleen, Nila Sathe, and Melissa McPheeters. How Does Nonpharmacological Care Affect Newborn Infants With Neonatal Opioid Withdrawal Syndrome? A Cochrane Review Summary With Commentary. RTI Press, July 2023. http://dx.doi.org/10.3768/rtipress.2023.rb.0033.2307.

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This paper summarizes the published Cochrane Review, “Non-pharmacological Care for Opioid Withdrawal in Newborns,” by A. Pahl, L. Young, M. E. Buus-Frank, L. Marcellus, and R. Soll (https://doi.org/10.1002/14651858.CD013217.pub2), and discusses it through a treatment policy and practice lens. The study population in the review included infants born at term (37 weeks’ gestation or greater) and late preterm (34 weeks’ gestation to 37 weeks’ gestation) who had a known or suspected prenatal exposure to opioids or who were exhibiting symptoms consistent with opioid withdrawal in the first 7 days of life. Nonpharmacological interventions included a wide range of care and were broadly categorized as: modification of environmental stimulation, feeding practices, and support of the mother-infant dyad. The review found that randomized controlled trials, identified in searches conducted in October 2019, did not provide enough evidence regarding clinically meaningful outcomes. However, recently published trial data suggest that “Eat, Sleep, Console,” an individualized, trauma-informed, family-centered nonpharmacological approach to care, can reduce the number of days an infant experiencing symptoms consistent with opioid withdrawal requires in-hospital care.

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Levi, Brittany E. Choledochal Cysts: In Brief with Dr. Alexander Bondoc. Stay Current, May 2022. http://dx.doi.org/10.47465/sc1.

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Choledochal cysts are a core pathology in pediatric surgery, affecting 1/100,000 live births in the western world, and 1/13,000 in eastern asia. These cysts are classified by the Todani classification, types I-V, in respect to their location and underlying pathophysiology. Infants and children presenting with stigmata of biliary disease should undergo evaluation for choledocal cyst. Workup includes axial imaging, ultrasonography, and laboratory investigation. A liver biopsy is necessary in neonates and newborns to rule out cystic biliary atresia, which would require further evaluation and management. Large choledochal cysts may be visualized on prenatal ultrasound, and warrant referral to a fetal care center for postnatal work up and monitoring. Management of choledochal cysts is dependent on the anatomic variant and spans from ERCP with sphincterotomy, to cyst excision with ductal and alimentary tract reconstruction. Type V choledochal cysts may require liver transplantation. Long term follow up is required due to an enhanced risk of future malignancy, even after resection.

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Levi, Brittany E., Rodrigo G. Gerardo, Alexander J. Bondoc, Rachel E. Hanke, Chandler Gibson, Ellen M. Encisco, and Todd A. Ponsky. Choledochal Cysts: In Brief with Dr. Alexander Bondoc. Stay Current, May 2022. http://dx.doi.org/10.47465/sc00001.

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Choledochal cysts are a core pathology in pediatric surgery, affecting 1/100,000 live births in the western world, and 1/13,000 in eastern asia. These cysts are classified by the Todani classification, types I-V, in respect to their location and underlying pathophysiology. Infants and children presenting with stigmata of biliary disease should undergo evaluation for choledocal cyst. Workup includes axial imaging, ultrasonography, and laboratory investigation. A liver biopsy is necessary in neonates and newborns to rule out cystic biliary atresia, which would require further evaluation and management. Large choledochal cysts may be visualized on prenatal ultrasound, and warrant referral to a fetal care center for postnatal work up and monitoring. Management of choledochal cysts is dependent on the anatomic variant and spans from ERCP with sphincterotomy, to cyst excision with ductal and alimentary tract reconstruction. Type V choledochal cysts may require liver transplantation. Long term follow up is required due to an enhanced risk of future malignancy, even after resection.

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liu, cong, xing wang, rao chen, and jie zhang. Meta-analyses of the Effects of Virtual Reality Training on Balance, Gross Motor Function and Daily Living Ability in Children with Cerebral Palsy. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0137.

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Review question / Objective: Cerebral palsy (CP) is a non-progressive, persistent syndrome occurring in the brain of the fetus or infant[1]. The prevalence of CP is 0.2% worldwide, and the prevalence can increase to 20-30 times in preterm or low birth weight newborns. There are about 6 million children with CP in China, and the number is increasing at a rate of 45,000 per year. Virtual reality (VR) refers to a virtual environment that is generated by a computer and can be interacted with.VR can mobilize the visual, auditory, tactile and kinesthetic organs of CP, so that they can actively participate in the rehabilitation exercise. Information sources: Two researchers searched 5 databases, including Pubmed (N=82), Embase (N=191), The Cochrane Library (N=147), Web of Science (N=359) and CNKI (N=11).

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EUROPEAN STANDARDS OF CARE FOR NEWBORN HEALTH. Chernivtsi, Ukraine: Higher State Educational Establishment of Ukraine Bukovinian State Medical University, 2019. http://dx.doi.org/10.24061/2413-4260.ix.3.33.2019.1.

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Medical treatment and care for preterm and sick newborn babies in European countries varies greatly. Significant differences are not only limited to the survival rates of such infants. In some European countries, preterm birth is also more commonly associated with chronic physical and mental disability than in others. This effect is exacerbated by the fact that in some parts of Europe, further assistance to these vulnerable children after discharge from the hospital (follow-up and early intervention) is not structured or even does not exist at all. Given the high level of inequality in health care delivery, agreed definitions and clear recommendations for infrastructure, medical processes, care procedures, and staffing capabilities are needed to compare and adjust the conditions of care in Europe. Therefore, there is an absolute need to ensure that high-level care is equally available throughout and for everyone. European standards of care for newborn health, developed on the initiative and under the project of the European Foundation for the Care of Newborn Infants (EFCNI), will help to overcome differences in clinical practice, structure and organization of care, as well as training of healthcare professionals. This publication presents the part of the standards regarding health care for preterm and sick infants.

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Towards safe womanhood: Supporting safe motherhood initiatives and women's participation in development. Population Council, 1998. http://dx.doi.org/10.31899/rh1998.1047.

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Improvement in a woman’s quality of life is a prerequisite for development of human resources, because the quality of children’s physical and mental development is inextricably tied to the health and welfare of women as future mothers. If a mother is well protected during the pregnancy, birth, and postpartum period, the risk of illness and other problems in fetuses and newborn babies will be reduced. On the other hand, if a woman does not survive the pregnancy, birth, and postpartum period, her fetus or newborn will also be threatened. This paper provides a situation analysis of pregnant women, women in labor, and postpartum mothers, presenting also the level of morbidity and mortality of fetuses in the perinatal period (pregnancy from 28 weeks until the newborn is 7 days old), and, in more depth, the level of morbidity or mortality of infants in the neonatal period (age 0–28 days). Also presented are the risks and needs of reproductive-age couples or women of reproductive age (15–49 years), which require intervention at the individual, family, community, environmental, and national levels.

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Infants of mothers with eating disorders show neurobehavioural and cognitive defects. ACAMH, July 2018. http://dx.doi.org/10.13056/acamh.10563.

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Eating disorders can have serious adverse clinical, social and psychological outcomes in affected patients, but whether maternal eating disorders are associated with negative outcomes in newborns is unknown.

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Providers’ emotional wellness: A, B, Cs of provider self-care when working with sick children and their families. Population Council, 2021. http://dx.doi.org/10.31899/sbsr2021.1085.

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A formative study was conducted under the Breakthrough RESEARCH project by the Population Council to understand the manifestation of mistreatment and experience of newborns, infants, and young children and co-design (with families and providers) a set of interventions that promote a positive experience of care. This poster is one of the job aids/tools created for the intervention.

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