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Dissertations / Theses on the topic 'Infection – Parasitology'

Author: Grafiati

Published: 10 December 2022

Last updated: 31 July 2025

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1

Tallin, Michelle. "The biology of Mesocestoides corti infection in laboratory rodents." Thesis, University of Portsmouth, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241075.

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2

Marley, Angela Kerstin. "Differential roles for dendritic cell subsets during Schistosoma mansoni infection." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/21684.

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Schistosoma mansoni infection leads to chronic inflammation and detrimental granulomatous pathology mediated largely by Th2 immune responses. Dendritic cells (DCs) provide an essential link between the innate and the adaptive immune response, and are critical for Th2 induction during S. mansoni infection. But the function of DCs in this process and the specific mechanisms they employ are not yet fully understood. Indeed, the role for individual DC subsets during the induction of Th2 responses is also unclear. Furthermore, the importance of DCs during the formation of granulomatous legions, and

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3

Maema, Malefane M. "Dynamics of repeated infection of high and low responder inbred mice with Heligmosomoides polygyrus." Thesis, Imperial College London, 1986. http://hdl.handle.net/10044/1/38092.

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4

Roberts, David John. "A study of the antigenic and adhesive phenotypes expressed at the surface of erythocytes infected with Plasmodium falciparum." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239316.

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5

Cooper, Deborah. "T cell responses evoked by Schistosoma mansoni infection in the mouse." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239751.

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6

Gomez, Gonzalez Maria. "«Leishmania»-macrophage interactions: regulations of protein tyrosine phosphatases and its implication in the outcome of infection." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40736.

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The outcome of Leishmania infection depends both on host and pathogen factors. Macrophages, the specialized host cell for uptake and intracellular development of Leishmania parasites, play a central role in the control of infection. Underlying their effector and accessory functions is the activation of signalling pathways, which in turn are largely controlled by events of protein phosphorylation. Consequently, the regulation of protein kinase and phosphatase activities results critical for the sequential progression of the signalling cascade, and therefore for the control of antimicrobial and

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7

Odiere, Maurice. "Energetic, morphologic and physiologic responses during «Heligmosomoides bakeri» (Nematoda) infection and protein deficiency in pregnant and lactating mice." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95137.

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This research investigated the concurrent effects of a gastrointestinal nematode infection Heligmosomoides bakeri, pregnancy, and protein deficiency (PD) during late pregnancy throughout lactation on energetic, morphologic and immunological responses in CD1 mice and their offspring. Our novel findings can be summarized broadly into three key themes: (i) energetics and resting metabolic rate, (ii) bone metabolism and (iii) immune development. This work highlights the largely independent ways in which the mouse responds to competing demands of pregnancy, infection, and PD. Pregnancy increased R

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8

Mathai, Sumreeta Bamotra. "Self-medication in Goats with Lespedeza cuneata in Response to Gastrointestinal Nematode Infection." Thesis, University of Louisiana at Lafayette, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10163267.

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<p> Resistance to synthetic anthelmintics has become a worldwide threat to various livestock species. The use of nutraceuticals and livestock management practices is being explored as an alternative to this issue. Foods containing a high amount of tannins are known to decrease gastrointestinal parasite infection. It is known that goats self-medicate by ingesting tannin-rich feed mixtures that they often avoid (Villalba et al. 2010). Studies have offered animals a particular mixture of feed that is known to be medicinal to decrease a parasite burden. In this study, we offered a tannin-rich plan

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9

Leonard, Cory A. "Microsporidia Spore Adherence and Host Cell Infection In Vitro." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etd/1191.

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Microsporidia infect invertebrate and vertebrate animals. Human pathogenic microsporidia are associated with severe disease in immunocompromised individuals, and mostly asymptomatic infection in the immunocompetent. Treatment options for microsporidiosis are limited, incompletely effective, and associated with toxicity. Furthermore, microsporidia infection of healthy individuals is poorly understood, and the consequences of asymptomatic infection have not been determined. Little is known about the molecular mechanisms of microsporidia infection, but such information is essential for the develo

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10

Dankwa, Selasi. "Sialic acid variation as a determinant of Plasmodium invasion of erythrocytes in malaria infection." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17467188.

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Sialic acids are acidic sugars that terminate glycan chains on proteins or lipids on vertebrate cell surfaces. They vary greatly in structure, presentation and amount, all of which are important physiologically, but can also impact the tissue and host tropism of diverse pathogens. Parasites of the genus Plasmodium cause malaria, a disease characterized by a cyclical process of parasite invasion of host erythrocytes, growth and replication and fresh invasion of new erythrocytes. During erythrocyte invasion – an event central to malaria pathogenesis – proteins on the surface of the parasite, kn

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11

Tuladhar, Rashmi. "ROLE OF COSTIMULATION IN EXPERIMENTAL LEISHMANIA MEXICANA INFECTION." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1395619402.

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12

Peterson, Jennifer Kate. "Life history consequences of infection with Chagas disease agent Trypansoma cruzi for its invertebrate host Rhodnius prolixus." Thesis, Princeton University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3686674.

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<p> Every interaction between species occurs in a heterogeneous environment that presents countless contexts that shape the interaction over time and space. The consequences of these interactions can regulate populations, as they trickle down to influence the genes that an individual passes on to its offspring, and then, in turn, scale back up to influence the genetic and phenotypic composition of future populations. In this work, I sought to uncover how these principles play out in the interactions between an invertebrate vector of human disease and the disease agent it carries. Disease vecto

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13

Duffy, Allyson Radford. "Relationship between dysphoric moods, risk-taking behaviors, and Toxoplasma gondii antibody titers in female veterans." Scholar Commons, 2013. http://scholarcommons.usf.edu/etd/4665.

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The number of female veterans is increasing daily. Previous research conducted on veterans has focused primarily on males or with small samples of females. Depression and suicidality are becoming increasingly evident in returning veterans. Toxoplasma gondii is an intracellular parasite that is common in the Middle East and has been reported to cause changes in personality and behavior. The purpose of the current study was to examine relationships between T. gondii antibody titer and socioeconomic variables, dysphoric moods, and risk-taking behaviors in a sample of 70 female veterans. Blood sam

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14

Mendonça, Daiane Barros Dias. "Análise do microbioma de bactérias de luz intestinal de hamsteres e sua correlação com LPS circulante, decorrente da translocação microbiana na leishmaniose visceral experimental." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/99/99131/tde-22012018-114555/.

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A leishmaniose visceral, na sua forma clinica ativa, caracteriza-se por febre de longa duração, hepatoesplenomegalia e caquexia. No Brasil, a letalidade é, em média, de 7% e as principais causas de morte são: hemorragia, comorbidade com doenças imunossupressoras e infecção bacteriana. O mecanismo de aumento de infecção bacteriana na LV não está claro e uma das hipóteses, é que pode haver translocação bacteriana da mucosa intestinal para o lúmen dos vasos sanguíneos e ocasionar uma maior severidade da resposta imuno-inflamatória e com consequente piora clínica. O objetivo deste trabalho foi ava

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15

Chéret, Antoine. "Etude de l'établissement des réservoirs VIH lors de la primo-infection et de l'impact des traitements antirétroviraux très précoces sur ces réservoirs." Phd thesis, Université René Descartes - Paris V, 2014. http://tel.archives-ouvertes.fr/tel-01059807.

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La primo-infection est un moment critique de l'établissement du réservoir justifiant de l'initiation d'un traitement précoce. Nous avons initié un essai randomisé évaluant l'impact de deux ans d'un traitement antirétroviral intense (essai ANRS147 OPTIPRIM, trithérapie versus pentathérapie) sur le réservoir et avons initié des études physiopathologiques au cours de cet essai. Nous montrons ainsi la faible diversité génétique des virus en primo-infection dans les compartiments sanguins et rectaux. Le réservoir s'établit dès le premier mois de l'infection par diffusion d'un cluster viral homogène

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16

Anderson, Barry Clayton. "The Response of Mice to Infection by the Parasitic Nematode Trichinella: A Comparison of Trichinella Spiralis and Trichinella Pseudospiralis." PDXScholar, 2002. https://pdxscholar.library.pdx.edu/open_access_etds/1658.

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The intracellular parasite Trichinella is a genus in phylum Nematoda that contains six named species including Trichinella spiralis and Trichinella pseudospiralis. These parasites infect a large variety of wild and domestic animals, human beings and a few species of birds. The parasitic strategies and the pathological effects on the host between trichinella spiralis and Trichinella pseudospiralis are quite different. The purpose of this study is to gain an understanding of the physiological, immunological and pathological differences between these two species of Trichinella using infections in

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17

Thierry, Simon. "Etude de la diversité génétique d'Aspergillus fumigatus et de Chlamydophila psittaci chez les oiseaux et mise au point de modèles expérimentaux aviaires." Phd thesis, AgroParisTech, 2011. https://pastel.hal.science/docs/00/60/37/70/PDF/these_Simon_THIERRY.pdf.

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Le champignon filamenteux Aspergillus fumigatus et la bactérie Chlamydophila psittaci sont deux agents pathogènes majeurs chez les oiseaux d'élevage. Bien que phylogénétiquement très distants, ces deux micro-organismes partagent un même mode de transmission par voie aérienne. La mortalité et la morbidité associées aux aspergilloses ou aux chlamydioses ont un impact économique qui n'est pas négligeable, en particulier dans les élevages de dindes. En France, les investigations autour de cas humains de chlamydiose identifient fréquemment un lien avec des élevages de canards, chez lesquels l'infec

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Thierry, Simon. "Etude de la diversité génétique d'Aspergillus fumigatus et de Chlamydophila psittaci chez les oiseaux et mise au point de modèles expérimentaux aviaires." Phd thesis, AgroParisTech, 2011. http://pastel.archives-ouvertes.fr/pastel-00603770.

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Le champignon filamenteux Aspergillus fumigatus et la bactérie Chlamydophila psittaci sont deux agents pathogènes majeurs chez les oiseaux d'élevage. Bien que phylogénétiquement très distants, ces deux micro-organismes partagent un même mode de transmission par voie aérienne. La mortalité et la morbidité associées aux aspergilloses ou aux chlamydioses ont un impact économique qui n'est pas négligeable, en particulier dans les élevages de dindes. En France, les investigations autour de cas humains de chlamydiose identifient fréquemment un lien avec des élevages de canards, chez lesquels l'infec

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19

Makin, Laura. "Secretion from the Leishmania flagellum as a potential mechanism of virulence factor delivery." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:a5da360c-e338-49d4-828d-0479bfa4480d.

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Protozoa of the Leishmania genus are transmitted between mammalian hosts by the sandfly and cause the neglected tropical disease leishmaniasis. Upon injection into the mammalian host by the sandfly promastigote-form parasites are phagocytosed by macrophages, where they differentiate into amastigotes. Although many virulence factors are known to modulate macrophage signalling pathways to favour infection, the delivery mechanisms are largely unknown. During differentiation to amastigotes the promastigote flagellum shortens dramatically and the fate of the excess flagellar membrane is unknown. He

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20

Almeida, Isis Almeida de. "Prevalência de enteroparasitos em crianças hospitalizadas em Pelotas, Rio Grande do Sul, Brasil." Universidade Federal de Pelotas, 2013. http://repositorio.ufpel.edu.br/handle/ri/2324.

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Made available in DSpace on 2014-08-20T14:31:29Z (GMT). No. of bitstreams: 1 dissertacao_isis_almeida.pdf: 2008353 bytes, checksum: d2f0dbd897b4e60effb16cb39f16d38d (MD5) Previous issue date: 2013-02-28<br>Intestinal parasite infections are diseases caused by protozoa and helminth groups. They are common in developing countries and are the most frequent diseases especially among children. Although it is known that hospitalized children may be more susceptible to intestinal parasites, because they are usually neglected, few studies describe the prevalence. This study aimed to investigate th

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21

Hinke, Tiene Zingano. "Perfil nosológico da população ribeirinha do baixo rio Machado em Rondônia / Amazônia Ocidental - Brasil." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42135/tde-03032010-101656/.

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Foi estudado o perfil nosológico da população ribeirinha do Baixo Rio Machado em Rondônia, área de Amazônia Ocidental no Brasil. Neste estudo, escolhemos abordar o perfil das seguintes doenças: malária, hepatite viral B e C, parasitose intestinal e papilomavírus humano. Estas doenças foram priorizadas devido à importância clínica e epidemiológica e também escassez de estudos referentes nas populações ribeirinhas amazônicas. Para isto, foi realizado um estudo descritivo no Baixo Rio Machado que se localiza a 250 km de Porto Velho (capital do Estado de Rondônia) pela margem direita do Rio Madeir

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22

Riley, Sharon Lesley. "The response of different laboratory rodents to Mesocestoides corti (Cestoda), tetrathyridia infections." Thesis, University of Portsmouth, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304450.

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23

Bukhari, Zia. "Cryptosporidium infections in livestock and the significance of environmental contamination with oocysts." Thesis, University of Strathclyde, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309045.

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24

Paula, Catia Dejuste de. "Patologia comparada de infecções selecionadas de anfíbios anuros de vida livre do bioma da Mata Atlântica: estudo prospectivo." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/10/10133/tde-19102012-154735/.

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Os anfíbios apresentaram um severo declínio de suas populações nas últimas décadas. Dentre as diversas causas dos declínios estão as doenças infecciosas. O presente trabalho tem o objetivo de estudar a ocorrência de enfermidades selecionadas que podem acometer estes animais na Mata Atlântica brasileira, e, desta forma, contribuir para a melhor compreensão das conseqüências destas enfermidades para a conservação dos anfíbios em nosso meio. Foram coletados 120 animais da Estação Biológica da Boracéia e realizaram-se exames necroscópicos, histopatológicos, microbiológicos, parasitológicos e PCR c

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Dwivedi, Ankit. "Functional analysis of genomic variations associated with emerging artemisinin resistant P. falciparum parasite populations and human infecting piroplasmida B. microti." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT073/document.

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Le programme d’élimination du paludisme de l’OMS est menacé par l’émergence etla propagation potentielle de parasites de l’espèce Plasmodium falciparum résistants à l’artémisinine. Récemment il a été montré que (a) des SNPs dans une région du chromosome 13 subissaient une forte sélection positive récente au Cambodge,(b) plusieurs sous-populations de parasites de P. falciparum résistants et sensibles à l’artémisinine étaient présentes au Cambodge, (c) des mutations dans le domaine Kelch du gène k13 sont des déterminants majeurs de la résistance à l’artémisinine dans la population parasitaire ca

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Currie, Rachel MacLeod. "Immunoepidemiology of Trichuris trichiura T. muris and Ascaris lumbricoides infections." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299976.

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27

Weirather, Jason Lee. "Computational approaches to the study of human trypanosomatid infections." Thesis, The University of Iowa, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3609102.

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<p> Trypanosomatids cause human diseases such as leishmaniasis and African trypanosomiasis. Trypanosomatids are protists from the order Trypanosomatida and include species of the genera <i>Trypanosoma</i> and <i> Leishmania</i>, which occupy a similar ecological niche. Both have digenic life-stages, alternating between an insect vector and a range of mammalian hosts. However, the strategies used to subvert the host immune system differ greatly as do the clinical outcome of infections between species. The genomes of both the host and the parasite instruct us about strategies the pathogens u

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Halpenny, Carli. "Interrelationships among gastrointestinal infections, stunting and their socio-ecological determinants in impoverished Panamanian preschool children: a spatio-temporal ecohealth approach." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114379.

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Background: Although growth stunting, height for age Z score (HAZ) <-2SD, results from sustained poor diet and frequent infection both of which are influenced by social and biophysical factors, few studies have used a transdisciplinary ecohealth framework for a comprehensive analysis of this relationship. Objective: To examine the interrelationships between preschool child stunting and gastrointestinal infections within the biophysical, social and spatial context of extreme poverty among the Ngäbe in Western Panama where conditional food voucher (FV) and cash transfer (CT) programs occurred.

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29

Peterka, Cássio Roberto Leonel. "Avaliação do efeito da fragmentação florestal na diversidade de carrapatos e patógenos transmitidos por carrapatos ma região do Pontal Paranapanema, SP." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-17042009-144842/.

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Avaliou-se o impacto da fragmentação florestal na diversidade de carrapatos de vida-livre e a presença de patógenos nestes carrapatos em remanescentes florestais do Pontal do Paranapanema, estado de São Paulo, Brasil. Estes fragmentos florestais abrigam uma rica e importante biodiversidade, com espécies endêmicas e ameaçadas como o mico-leão-preto (Leontopithecus chrysopygus), a anta (Tapirus terrestris), a onça pintada (Panthera onca), o macuco (Tinamus solitarius) e várias outras espécies de aves, mamíferos, répteis, anfíbios e peixes. Aproximadamente 90% das espécies de carrapatos parasitam

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Araujo, Ana Julia Urias dos Santos. "Estudo da ocorrência de infecção por Cryptosporidium spp (Apicomplexa: Cryptospordiidae) entre crianças do município de Taubaté- SP e caracterização genotípica de isolados clínicos do parasito." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-06022015-095557/.

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Objetivou-se, com o presente estudo, verificar a ocorrência de Cryptosporidium spp entre crianças do município de Taubaté-SP e realizar a genotipagem de isolados clínicos do parasito. Foram selecionadas 13 creches municipais, que atendiam crianças de 4 a 72 meses de idade, realizando-se implantação de um programa para busca ativa de casos de diarréia, com acompanhamento da população durante o ano de 2002. Para se conhecer o perfil coproparasitológico, realizou-se estudo transversal em quatro das 13 creches selecionadas. Foram examinadas 483 amostras fecais processadas pelo método de concentraç

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Marques, Ana Lúcia Silveira Lessa. "Aquisição passiva de anticorpos IgG maternos reativos com os lipopolissacarídeos de enterobactérias incidentes em infecções neonatais por recém-nascidos pré-termos e a termo." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42135/tde-16072009-152507/.

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As espécies Klebsiella pneumoniae, Escherichia coli e Pseudomonas aeruginosa são responsáveis por infecções neonatais hospitalares. Lipopolissacarídeo (LPS) é o principal indutor de respostas inflamatórias. Os objetivos foram avaliar a transferência placentária de IgG reativa ao LPS de K. pneumoniae, E. coli O111, O26 e O6 e P. aeruginosa empregando ELISA para dosar IgG em soro materno e de cordão de 29 neonatos pré-termos e 32 a termo; analisar IgM total e específica no soro materno; e investigar a influência das patologias apresentadas pelas mães na transferência placentária. Concentrações d

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Adams, Peter John. "Parasites of feral cats and native fauna from Western Australia: the application of molecular techniques for the study of parasitic infections in Australian wildlife." Thesis, Adams, Peter John (2003) Parasites of feral cats and native fauna from Western Australia: the application of molecular techniques for the study of parasitic infections in Australian wildlife. PhD thesis, Murdoch University, 2003. https://researchrepository.murdoch.edu.au/id/eprint/29/.

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A survey of gastro-intestinal parasites was conducted on faecal samples collected from 379 feral cats and 851 native fauna from 16 locations throughout Western Australia. The prevalence of each parasite species detected varied depending upon the sampling location. Common helminth parasites detected in feral cats included Ancylostoma spp. (29.8%), Oncicola pomatostomi (25.6%), Spirometra erinaceieuropaei (14%), Taenia taeniaeformis (4.7%), Physaloptera praeputialis (3.7%) and Toxocara cati (2.6%). The most common protozoan parasites detected in feral cats were Isospora rivolta (16.9%) and I. fe

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Adams, Peter John. "Parasites of feral cats and native fauna from Western Australia : the application of molecular techniques for the study of parasitic infections in Australian wildlife /." Adams, Peter John (2003) Parasites of feral cats and native fauna from Western Australia: the application of molecular techniques for the study of parasitic infections in Australian wildlife. PhD thesis, Murdoch University, 2003. http://researchrepository.murdoch.edu.au/29/.

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A survey of gastro-intestinal parasites was conducted on faecal samples collected from 379 feral cats and 851 native fauna from 16 locations throughout Western Australia. The prevalence of each parasite species detected varied depending upon the sampling location. Common helminth parasites detected in feral cats included Ancylostoma spp. (29.8%), Oncicola pomatostomi (25.6%), Spirometra erinaceieuropaei (14%), Taenia taeniaeformis (4.7%), Physaloptera praeputialis (3.7%) and Toxocara cati (2.6%). The most common protozoan parasites detected in feral cats were Isospora rivolta (16.9%) and I. fe

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Babayan, Simon A. "Mécanismes de contrôle de la croissance, des mues et de la microfilaremie dans le modèle murin de filariose, litomosoides sigmodontis." Paris 6, 2004. http://www.theses.fr/2004PA066359.

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Mazet, Muriel. "Culture in vitro et caractérisation d'enzymes hydrogénosomales chez Histomonas meleagridis, protozoaire flagellé parasite de gallinacés." Phd thesis, Université Blaise Pascal - Clermont-Ferrand II, 2007. http://tel.archives-ouvertes.fr/tel-00718217.

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Le protozoaire flagellé Histomonas meleagridis est responsable d'une maladie chez les oiseaux galliformes, nommée histomonose. La culture in vitro de ce parasite anaérobie est qualifiée d'agnobiotique car il y a présence d'une flore bactérienne non déterminée. L'identification des bactéries dans cette flore montre l'existence d'une flore très diversifiée. Des essais de culture axénique et monoxénique suggèrent que les bactéries sont essentielles au développement in vitro du parasite. Par des stratégies de PCR, RT-PCR et RACE-PCR, nous avons les gènes complets codant trois protéines intervenant

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Machado, Lisa Santos. "The inhibitory activity of synthetic compounds and ions against transporters of multi-drug resistant bacteria." Master's thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2011. http://hdl.handle.net/10362/7712.

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RESUMO: Sessenta e três derivados de hidantoína foram utilizados para avaliar possíveis efeitos de modulação na actividade das bombas de efluxo (BE) na Salmonella NCTC 13349 utilizando um método fluorimétrico semi-automático. Nenhum dos compostos apresentaram actividade anti-bacteriana até concentrações de 240 mg/L. Entre todos os compostos, SZ-7 demonstrou possuir propriedades de modulação de effluxo na presença de glucose. Para testar esta actividade, estirpes de Salmonella resistentes à ciprofloxacina, induzidas a elevados níveis de resistência com sobre-expressão de BE, foram expostas ao S

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Roca, Geronès Xavier. "Caracterització morfològica i molecular i estudi epidemiològic d’espècies d’Anisakis i Hysterothylacium (Nematoda: Ascaridoidea) en peixos de consum habitual procedents de l’Atlàntic Nord-Est i del Mediterrani." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/668343.

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Aquest treball engloba l’estudi d’espècies de nematodes ascaridoïdeus de les famílies Anisakidae i Raphidascarididae paràsites de peixos marins arreu del món que presenten un interès sanitari i/o comercial. Dins la família Anisakidae, les espècies del gènere Anisakis són les principals causants de l’anisakiosi en humans pel consum de peix cru o insuficientment cuinat parasitat amb larves; malaltia alimentària considerada com emergent, la qual pot cursar amb símptomes gastrointestinals i/o al·lèrgics. El gènere Hysterothylacium de la família Raphidascarididae comprèn espècies que, tot i ser con

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Carregal, Virgínia Mendes. "Comparação de métodos de PCR e amostras clínicas para o diagnóstico de leishmaniose visceral em cães assintomáticos." CNEN - Centro de Desenvolvimento da Tecnologia Nuclear, Belo Horizonte, 2011. http://www.bdtd.cdtn.br//tde_busca/arquivo.php?codArquivo=163.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>A leishmaniose visceral (LV) é um grave problema de saúde pública no Brasil. Na área urbana o cão é a principal fonte de infecção e o controle da LV no Brasil envolve a eliminação de cães infectados. Testes sorológicos são utilizados para os levantamentos rotineiros, mas estes apresentam problemas de especificidade e sensibilidade. Os métodos moleculares como a PCR são úteis tanto no diagnóstico como na identificação das espécies de Leishmania. São capazes de detectar animais infectados soronegativos e são mais sensíveis e específi

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Paixão, Paulo Jorge Pereira Cruz. "Contributo para o estudo da infecção congénita pelo vírus citomegálico em Portugal." Doctoral thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2009. http://hdl.handle.net/10362/5101.

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Resumo O vírus citomegálico humano (CMV) é o principal agente de infecção congénita, atingindo cerca de 0.2 a 2.2% de todos os recém-nascidos. As crianças que nascem infectadas por este vírus têm cerca de 11% a 12.7% de probabilidades de apresentarem sintomas e sinais de doença citomegálica ao nascimento, podendo cerca de 40 a 58% destas virem a apresentar sequelas neurológicas permanentes. Das crianças infectadas que terão infecção assintomática no período neo-natal, 5 a 15% poderão vir igualmente a sofrer de sequelas tardias, sobretudo a surdez ou o atraso mental. Em Portugal, descon

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Janeiro, David Gonçalo Pinho. "Sífilis congénita : caracterização da infecção e avaliação de técnicas laboratoriais para o seu diagnóstico." Master's thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2012. http://hdl.handle.net/10362/7717.

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RESUMO: Um dos maiores problemas da sífilis é a infecção intra-uterina do feto, que pode resultar em morte fetal com aborto espontâneo. Os objectivos desta tese foram comparar os cinco testes serológicos para o diagnóstico de sífilis congénita e optimizar e aplicar a várias amostras clínicas, colhidas de indivíduos com suspeita de infecção por Treponema pallidum, uma técnica de PCR-Multiplex e uma técnica de PCR em tempo real. Na globalidade dos soros estudados obtiveram-se os seguintes resultados: o RPR reactivo em 87/517; TPHA reactivo em 135/517; e EIA reactivo em 127/517. A pesquisa de a

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FELIX, Rute Castelo. "The role of detoxification in the mosquito Anopheles gambiae response to Plasmodium infection." Doctoral thesis, Instituto de Higiene e Medicina Tropical, 2011. http://hdl.handle.net/10362/7212.

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A malária, uma das doenças mais devastadoras que ocorrem em África é causada por um parasita do género Plasmodium e é transmitida aos humanos por mosquitos vectores do género Anopheles durante a refeição de sangue. Apesar da resposta do mosquito à infecção por Plasmodium ter vindo a ser intensamente estudada nos últimos anos, as interacções entre o mosquito vector e o parasita são muito complexas e, estão longe de serem completamente compreendidas. Este estudo tem como objectivo principal contribuir para o conhecimento da resposta do mosquito à infecção por Plasmodium, focando-se no papel das

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BRÁS, Daniela Cristina de Henriques. "Mechanisms of inhibition of Plasmodium liver infection by amino acid supplementation." Master's thesis, Instituto de Higiene e Medicina Tropical, 2018. http://hdl.handle.net/10362/52857.

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A malária é uma das doenças infeciosas mais prevalentes no mundo1. É causada por parasitas protozoários do género Plasmodium, os quais são transmitidos aos seus hospedeiros mamíferos através da picada de um mosquito Anopheles fêmea infetado1,2. A primeira fase da infeção, obrigatória e assintomática, ocorre no fígado e é iniciada quando os esporozoítos injetados invadem os hepatócitos do hospedeiro2,3. Aí, os parasitas diferenciam-se e desenvolvem-se até se formarem merozoitos, que são libertados na corrente sanguínea, infetando ciclicamente os eritrócitos e causando os sintomas da malária2,3.

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Cassagne, Carole. "Identifications de champignons d'intérêt médical en mycologie et parasitologie par spectrométrie de masse de type MALDI-TOF : applications au diagnostic des infections fongiques." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM5064.

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L’avènement de la spectrométrie de masse de type MALDI-TOF a révolutionné la microbiologie en permettant l’identification précise des bactéries et des levures en seulement quelques minutes. En 2010, la MALDI-TOF SM n’était pas applicable à l’identification des champignons filamenteux. Un protocole d’identification générant des spectres interprétables de champignons filamenteux fut d’abord mis au point, suivi par le développement d’une architecture de banque originale. Enfin une banque de références solides, intégrant des références pour la majorité des espèces de moisissures impliquées en path

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Leite, Rodrigo Souza. "Diagnostico molecular da Leishmaniose visceral canina: avaliação do swab conjuntival em cães assintomáticos e em cães vacinados." CNEN - Centro de Desenvolvimento da Tecnologia Nuclear, Belo Horizonte, 2010. http://www.bdtd.cdtn.br//tde_busca/arquivo.php?codArquivo=122.

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Nenhuma<br>O controle epidemiológico da leishmaniose visceral (LV) no Brasil envolve a eliminação de cães infectados, portanto, métodos diagnósticos confiáveis são essenciais para evitar a transmissão da doença ou o sacrifício desnecessário de animais. O programa de controle da LV no Brasil é baseado em inquéritos sorológicos. Os métodos sorológicos, no entanto, apresentam problemas de sensibilidade e especificidade. A Reação em Cadeia da Polimerase (PCR) demonstrou ser uma técnica rápida e sensível para a detecção de Leishmania, no entanto amostras não invasivas representam um instrumento ess

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Minguez, Laëtitia. "Les interactions "hôte-parasites-environnement" dans la bioévaluation de la qualité des milieux : l'exemple du système Dreissena polymorpha et ses parasites." Thesis, Metz, 2011. http://www.theses.fr/2011METZ042S.

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De plus en plus d’études montrent l’importance de considérer les parasites dans les études de biosurveillance environnementale car ils peuvent représenter des facteurs confondants en modifiant la physiologie de leurs hôtes et des bioindicateurs de la qualité des milieux. Dans ce contexte, le bivalve dulçaquicole Dreissena polymorpha a été choisi comme un modèle hôte, organisme couramment utilisé dans les études écotoxicologiques. Le potentiel effet confondant de différents parasites (i.e. bactéries intracellulaires, ciliés, trématodes a été, in situ sur plusieurs populations hôtes échantillonn

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Beaudry, Jeanette T. "Effect of hemoglobins S and C on the in vivo expression and immune recognition of Plasmodium falciparum erythrocyte membrane protein 1 variants in Malian children." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:21f27887-e7e8-4480-a8e4-c7072f3b392c.

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The enormous mortality burden exerted by P. falciparum malaria has evolutionarily selected for red blood cell (RBC) polymorphisms which confer protection against the severe manifestations of this disease. Although the epidemiological protection by these polymorphisms has been well-established for the past half-century, the mechanisms underlying this protection are still being uncovered. Recent studies implicate impaired cytoadherence to microvascular endothelial cells (MVECs) due to reduced surface levels and altered display of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) as a

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Longley, Rhea Jessica. "Liver-stage vaccines for malaria." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:b5c9821c-db32-4b66-a315-02541e62f566.

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The development of an efficacious P. falciparum malaria vaccine remains a top priority. Pre-erythrocytic vaccine efforts have traditionally focussed on two well- known antigens, CSP and TRAP, yet thousands of antigens are expressed throughout the liver-stage. The work described in this thesis aimed to assess the ability of other pre-erythrocytic antigens to induce an immune response and provide protective efficacy against transgenic parasites in a mouse model. Research undertaken in our laboratory has demonstrated the ability of prime-boost viral vectored sub-unit vaccination regimens to elici

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Luiza, Batista Camilla. "Humanized mice as model for Plasmodium vivax infection." Electronic Thesis or Diss., Sorbonne université, 2021. http://www.theses.fr/2021SORUS232.

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Le paludisme est une maladie transmise par les moustiques causée par des espèces de Plasmodium, parmi lesquelles P. falciparum et P. vivax représentent problème de santé majeur avec plus de 400 000 victimes et 250 millions de cas cliniques signalés chaque année. P. vivax est reconnu comme une maladie débilitante et terrible. La mauvaise compréhension de la biologie des parasites est due au manque de culture à long terme et de modèles murins fidèles, ce qui reste difficile en raison de son tropisme pour les globules rouges (GR) immatures CD71+. Le nouveau modèle chimérique appelé HERYHIS pour H

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ANTUNES, Sandra Isabel da Conceição. "Differential expression and functional characterization of cattle tick genes in response to pathogen infection (Babesia bigemina)." Doctoral thesis, Instituto de Higiene e Medicina Tropical, 2014. http://hdl.handle.net/10362/19273.

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O conceito “One health” reconhece a necessidade do trabalho conjunto de veterinários, profissionais de saúde e cientistas, dada a interface dinâmica entre pessoas, animais e ambiente. Este conceito é muito importante em zoonoses, tais como doenças associadas a carraças (DAC´s) que dependem de animais como reservatório. Os protozoários do género Babesia são agentes patogénicos transmitidos por carraças que causam a doença denominada babesiose num variado número de animais incluindo o Homem. Particularmente a B. bovis e B. bigemina são transmitidas por carraças, relacionadas com gado, Rhipicepha

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Adams, John Peter. "Parasites of feral cats and native fauna from Western Australia the application of molecular techniques for the study of parasitic infections in Australian wildlife /." Connect to this title online, 2003. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20040730.142034.

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