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Dissertations / Theses on the topic 'Infectious disease clinic'

Author: Grafiati

Published: 4 June 2021

Last updated: 3 February 2022

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1

Brittz, Marize. "Clinical utility of mobile and automated hearing health technology in an infectious disease clinic setting." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/63970.

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Decentralised detection and monitoring of hearing loss can be supported by new mHealth technologies using automated testing, which can be facilitated by minimally trained persons. These technologies may prove particularly useful in an infectious disease (ID) clinic setting where patients are at high risk for hearing loss. The current study aimed to evaluate the clinical utility of mobile and automated audiometry hearing health technology in an ID clinic setting. The current study was exploratory as it aimed to determine whether smartphone automated audiometry and South African English Digits-

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2

Mabuza, Poppy Lydia. "The impact of HIV serodiscordancy on married couples attending the infectious diseases clinic at 1 Military Hospital." Diss., University of Pretoria, 2010. http://hdl.handle.net/2263/27273.

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HIV/AIDS is severely affecting the armed forces in South Africa. Combating HIV/AIDS demands a high level of commitment from the Ministry of Defence and all the Divisions and Services at all levels in the Department of Defence. Prevention practice for HIV/ AIDS is a challenged because the nature and full extent of the impact on the forces, and in particular on serodiscordant couples, are not known. This research study explored the experiences of serodiscordant couples regarding the impact of serodiscordancy on their marriages. The Infectious Disease Clinic engages serodiscordant couples as acti

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3

Ye, X., J. N. Van, F. M. Munoz, et al. "Noroviruses as a Cause of Diarrhea in Immunocompromised Pediatric Hematopoietic Stem Cell and Solid Organ Transplant Recipients." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/1490.

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Case reports describe significant norovirus gastroenteritis morbidity in immunocompromised patients. We evaluated norovirus pathogenesis in prospectively enrolled solid organ (SOT) and hematopoietic stem cell transplant (HSCT) patients with diarrhea who presented to Texas Children's Hospital and submitted stool for enteric testing. Noroviruses were detected by real-time reverse transcription polymerase chain reaction. Clinical outcomes of norovirus diarrhea and non-norovirus diarrhea patients, matched by transplanted organ type, were compared. Norovirus infection was identified in 25 (22%) of

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4

Chorazy, Margaret Lynn. "Polymicrobial respiratory tract infections in a hospital-based pediatric population, with particular emphasis on the role of human rhinoviruses." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/788.

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Pediatric acute respiratory tract infections (ARTIs) are a leading cause of morbidity and mortality. The objectives of this study were to describe the epidemiology of polymicrobial ARTI in a hospital-based pediatric population and to investigate the association of polymicrobial infection and severity of illness. We conducted a retrospective study of 559 archived respiratory specimens from 421 children under the age of 10 years collected from March 28, 2008 through June 30, 2009 and stored by the University of Iowa Hospital and Clinics Clinical Microbiology Laboratory. Specimens were tested by

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5

Rojek, Amanda. "Improving patient centred research during infectious disease outbreaks." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:8a53052f-9585-4709-a06e-15586826efce.

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Emerging infectious diseases (EIDs) constitute an important global health security problem. During EID outbreaks, patient centred research can play a significant role in informing evidence-based care for patients, in calibrating public health responses, and in directing effective policy and research. However, to date, this type of research has been limited in impact. This thesis sets out to improve the value of patient centred research in combating EID outbreaks. It provides a structured analysis of what has previously constrained efforts to rapidly accumulate high-quality evidence. It provide

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6

Lee, Man-ching Anney. "Effects of the disease management programme with nurse-led heart failure clinic." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B40721036.

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7

Oppenheimer, Stephen James. "Iron deficiency and susceptibility to infection : a prospective study of the effects of iron deficiency and iron prophylaxis in infants in Papua New Guinea." Thesis, University of Oxford, 1987. http://ora.ox.ac.uk/objects/uuid:1891d054-1564-47f5-b2e0-b6da5f60e996.

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Investigation of the relationship between iron deficiency, iron supplementation and susceptibility to infection, was suggested by the author's initial observations of an association of anaemia with serious bacterial infections in infancy in Papua New Guinea. The bulk of previous longitudinal clinical intervention studies in infancy showed beneficial effects of iron supplementation. However, defects of control and design and recording in these studies and contradictory anecdotal reports left the question unresolved. A prospective, placebo-controlled, randomised, double-blind trial of iron proph

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8

Clauson, John. "Cryptococcus neoformans Serotype Groups Found in Clinical and Environmental Isolates." TopSCHOLAR®, 1993. http://digitalcommons.wku.edu/theses/1888.

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Cryptococcus neoformans is an encapsulated yeast responsible for severe meningoencephalitis. The importance of epidemiological studies on cryptococcosis has increased since the beginning of the AIDS epidemic. C. neoformans exists in two varieties containing four serotypes, C. neoformans var. neoformans (serotypes A and D) and C. neoformans var. gattii (serotypes B and C). Locally C. neoformans var. neoformans has been associated with pigeon feces during those months having an average temperature of 64.2°F j(17.8°C) and above. Clinical and environmental isolates of C. neoformans obtained from

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9

李雯靜 and Man-ching Anney Lee. "Effects of the disease management programme with nurse-led heart failure clinic." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B40721036.

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10

Estes, Andersen, and Demetrio Macariola. "A Clinical Differentiation of Multisystem Inflammatory Syndrome in Children (MIS-C) & Kawasaki Disease (KD)." Digital Commons @ East Tennessee State University, 2021. https://dc.etsu.edu/asrf/2021/presentations/27.

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INTRODUCTION: With the emergence of the COVID 19 pandemic, a new disease, Multisystem Inflammatory Syndrome in Children (MIS-C), had evolved. Increasing number of children are being reported to have MIS-C in the U.S. & worldwide. In the U.S. there are currently 2617 MISC cases reported. MIS-C & Kawasaki Disease (KD), have almost the same presentation, making clinical differentiation difficult. This study aims at differentiating KD & MIS-C which could assist clinicians to determine which one they could be dealing with in their practices. METHODS: Clinical features & laboratory values were colle

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11

Deitcher, Rebecca Ulman. "Health locus of control and HIV : a study of beliefs, attitudes, and high-risk behaviours among homosexual men attending a general medical clinic." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=39806.

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Acquired immunodeficiency syndrome (AIDS) remains an epidemic illness with no known cure. Survival time after infection with the human immunodeficiency virus (HIV), has been lengthened considerably. Rates of new infection among the at-risk male homosexual populations have decreased. Prevention is possible through effective, targeted interventions. This study is an exploration of the role or health locus of control, an individual difference construct from the area of social learning theory, in the maintenance of health-oriented behaviours, co-risk indicative behaviours, and high-risk behaviours

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12

Waddington, Claire Shelley. "Understanding typhoid disease : a controlled human infection model of typhoid fever." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:679ef7ec-b871-47a8-adea-d3fb3478e4b9.

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Typhoid disease, caused by infection with S. Typhi, is a significant cause of mortality and morbidity in resource–poor countries. Efforts have been made to generate a new generation of vaccines that are efficacious and can be given to infants, but have been hindered by a poor understanding of the protective immune response to S. Typhi infection, and in particular by the absence of a correlate of protection. Controlled human infection studies (‘challenge studies’) provide a model for investigating infectious diseases and appraising novel vaccines, including in typhoid disease. This DPhil descri

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13

朱祖順 and Cho-shun Chu. "A clinical, microbiological and radiological study of primary endodontic infections." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B38628788.

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14

Kapulu, Melissa Chola. "Pre-clinical development of viral vectored transmission-blocking malaria vaccines." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:a5610025-28e1-433f-9487-aaa1f6d641a0.

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Malaria transmission-blocking vaccine candidate antigens have been developed to induce antibodies using different delivery systems, mainly protein-in-adjuvant formulations, independently in various laboratories giving varied transmission-blocking activity (TBA). However, only one candidate antigen has been tested in clinical trials. In order to advance the most efficacious target(s) for possible clinical development, a rank order of the leading antigens based on TBA in a head-to-head comparison using a single delivery platform was made. Candidate antigens, AnAPN1, PfsHAP2, Pfs230-C, Pfs25, and

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15

Patel, Amit, Richard Veerman, Jodi Polaha, et al. "Addressing Gaps in Immunization Rates in a Family Medicine Residency Clinic." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/200.

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Adult immunizations effectively reduce morbidity, mortality, and transmission rates of multiple diseases; however, outpatient providers often a struggle to convince patients to accept vaccinations. This project’s aim is to address vaccination rates in our adult population, focusing first on the influenza vaccine in year one (2016), and then on pneumococcal vaccine in year two (2017), by 1) using a strong quality improvement strategy (known as a Champion Team) and 2) implementing a clinic program consisting of provider training, improved documentation, and informative posters targeted at patien

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16

Ehrenborg, Christian. "Bartonella Infections in Sweden: Clinical Investigations and Molecular Epidemiology." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7860.

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17

Mallon, Patrick William Gerard School of Medicine UNSW. "Clinical and molecular aspects of HIV-associated lipodystrophy." Awarded by:University of New South Wales. School of Medicine, 2006. http://handle.unsw.edu.au/1959.4/33048.

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HIV-associated lipodystrophy (HIVLD) syndrome is a condition comprising abnormalities in distribution of body fat and metabolism of lipids and glucose that arises in HIV-infected patients on long-term antiretroviral therapy. This thesis describes clinical research into aspects of the natural history and treatment of HIVLD, as well as molecular research into its pathogenesis centred on subcutaneous adipose tissue. Results demonstrate HIVLD to be a treatment-induced syndrome characterised by initial gains in body fat followed by selective, progressive loss of limb fat. Exposure to thymidineanalo

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18

Scott, James Cobb. "Script generation and multitasking in HIV-1 infection implications for everyday functioning /." Diss., [La Jolla] : [San Diego] : University of California, San Diego ; San Diego State University, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p3354893.

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Thesis (Ph. D.)--University of California, San Diego and San Diego State University, 2009.<br>Title from first page of PDF file (viewed June 16, 2009). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 118-130).

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19

Navér, Lars. "Perinatal HIV-1 infection : aspects on clinical presentation, viral dynamics and epidemiology /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-983-8/.

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20

Biswas, Sumi. "Prime boost vaccination with viral vectors targeting apical membrane antigen 1." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:a17ab4e4-9b81-4ab3-b02f-41d9da36c6ab.

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Apical membrane antigen 1 (AMA1) is a leading candidate vaccine antigen against blood stage malaria and several clinical trials using mostly protein-in-adjuvant vaccines have shown limited success. This thesis describes the development of recombinant adenoviral (AdHu5) and poxviral (MVA) vectors encoding AMA1 from Plasmodium chabaudi murine parasites. In this murine malaria model, AdHu5 and MVA encoding AMA1 when used in a heterologous prime boost regime showed excellent immunogenicity, both humoral and cellular. The vaccination regime was protective against blood stage challenge and both anti

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21

Galgiani, John N., Neil M. Ampel, Janis E. Blair, et al. "2016 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for the Treatment of Coccidioidomycosis." OXFORD UNIV PRESS INC, 2016. http://hdl.handle.net/10150/621661.

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It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. Infectious Diseases Society of America considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances. Coccidioidomycosis, also known as San Joaquin Valley fever, is a systemic infection endemic to parts of the southwestern United Stat

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22

Allison, Waridibo Evelyn National Centre in HIV Epidemiology &amp Clinical Research Faculty of Medicine UNSW. "Epidemiological and clinical aspects of diagnosing paediatric Human Immunodeficiency Virus (HIV) infection in a resource limited setting." Awarded by:University of New South Wales. National Centre in HIV Epidemiology & Clinical Research, 2009. http://handle.unsw.edu.au/1959.4/44515.

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Diagnosis of paediatric HIV infection presents a spectrum of challenges particularly in countries where resources are constrained. This program of research aims to illuminate epidemiological and clinical aspects of HIV diagnosis in resource limited settings focusing in particular on the nation of Papua New Guinea (PNG). This body of work commences with an exploration of current literature pertaining to diagnosis of HIV infection in resource constrained settings. This exploration encompasses the current epidemiological data available on HIV infection in the paediatric population worldwide, c

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23

Bollyky, Paul Laszlo. "Viral genetic diversity and clinical disease in Hepatitis B virus infection : a phylogenetic approach." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301179.

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24

Das, C. R. "Causes of non-adherence to antiretroviral therapy in Wellness Clinic, Tshepong Hospital, Klerksdorp." Thesis, Stellenbosch : University of Stellenbosch, 2009. http://hdl.handle.net/10019.1/97161.

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ENGLISH ABSTRACT: HIV/AIDS is the leading cause of death in Sub-Saharan Africa. According to 2001 estimates, there are 28.5 million people living with HIV in Africa, comprising more than 70% of the world’s HIV-infected population. HIV/AIDS remains one of the most important social and public health threats in Sub-Saharan Africa. UNAIDS 2006 estimates that 5.5 million people are living with HIV, and almost 1,000 AIDS deaths occur every day in South Africa. South Africa is currently one of the most severely affected countries in the world. Antiretroviral therapy (ART) is currently the only t

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25

Arendse, Carmen. "An evaluation of the effectiveness of a clinic-based HIV/AIDS counselling course on trainee functioning at work sites." Thesis, University of the Western Cape, 2002. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_1267_1365590967.

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26

Goliath, René. "A review of recruitment strategies within the Clinical Infectious Diseases Research Initiative (Cidri) Group from 2007-2013, 4 studies." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29769.

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The Clinical Infectious Diseases Research Group [CIDRI] has conducted high impact research over the last decade in Cape Town specifically in the townships of Khayelitsha and Mannenberg. None of this research would have been possible without robust strategies to recruit and retain study participants. Four different completed studies with different study designs have been selected, which will show the different approaches to participant recruitment into clinical research. This review will evaluate this process in relation to the approved protocol recruitment strategy, the amendments, which were

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27

Wrightson, John M. "Pathogen identification in lower respiratory tract infection." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:30c757ec-99b7-492e-a12e-ff996581863a.

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Treatment of lower respiratory tract infection (pneumonia and pleural infection) relies on the use of empirical broad spectrum antibiotics, primarily because reliable pathogen identification occurs infrequently. Another consequence of poor rates of pathogen identification is that our understanding of the microbiology of these infections is incomplete. This thesis addresses some of these issues by combining the acquisition of high quality lower respiratory tract samples, free from nasooropharyngeal contamination, with novel molecular microbiological techniques in an attempt to increase rates of

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28

Asafu-Agyei, Nana Akua. "Stigma Perceived by Persons With Human Immunodeficiency Virus Attending the Infectious Diseases Clinic of Centre Hospitalier Universitaire de Fann in Dakar, Senegal." Yale University, 2008. http://ymtdl.med.yale.edu/theses/available/etd-08062007-113316/.

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Human Immunodeficiency Virus (HIV)-associated stigma is pervasive throughout the world. This stigma affects the ability of HIV-positive individuals to cope with their illness and it also affects behaviors around sexual practices, disclosure to others and the use of healthcare. The purpose of the research project was to examine the experience of internalized stigma among HIV-positive persons and their perceptions of stigmatizing attitudes in the community. The study also examined disclosure of HIV serostatus and identified factors contributing to disclosure and stigma in Senegal, a low prevalen

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29

Sund, Fredrik. "Cytomegalovirus Infection in Immunocompetent and Renal Transplant Patients : Clinical Aspects and T-cell Specific Immunity." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Universitetsbiblioteket [distributör], 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9324.

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30

Ajudua, Febisola Ibilola. "Adherence to antiretroviral therapy at the Dora Nginza Hospital adult wellness clinic, Port Elizabeth, South Africa." Thesis, Stellenbosch : University of Stellenbosch, 2015. http://hdl.handle.net/10019.1/97197.

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Thesis (MFamMed)--Stellenbosch University, 2015.<br>ENGLISH SUMMARY: Background: Sub Saharan Africa is home to approximately two thirds of the world’s population of HIV positive individuals. In view of the socioeconomic challenges of the region governments have provided antiretroviral therapy free to improve chances of survival among patients. However, adherence to antiretroviral therapy is recognised as more important in predicting patient survival. Aim: The study aimed to describe the prevailing factors that influence adherence to antiretroviral therapy. Methods: The study design was carri

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McHenry, Michael Lyon. "Genomic and Co-Evolutionary Determinants of Clinical Severity in Active Tuberculosis Patients." Case Western Reserve University School of Graduate Studies / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case1623754259445275.

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32

Boqvist, Sofia. "Leptospira infection among pigs in southern Vietnam : aspects on epidemiology, clinical affection and bacteriology /." Uppsala : Dept. of Obstetrics and Gynaecology, Swedish Univ. of Agricultural Sciences ([Institutionen för obstetrik och gynekologi], Sveriges lantbruksuniv.), 2002. http://epsilon.slu.se/avh/2002/91-576-6374-2.pdf.

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33

Gray, Linsay Anne. "Clinical and biological disease progression in children with vertically acquired HIV-1 infection in Europe : statistical determinations." Thesis, University College London (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408032.

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34

Mahlalela, Maria Sizakele. "Factors contributing to non-adherence of patients to highly active antiretroviral treatment at Kanyamazane Clinic, Ehlanzeni District, Mpumalanga Province." Thesis, University of Limpopo, 2014. http://hdl.handle.net/10386/1427.

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Thesis (M.CUR.) --University of Limpopo, 2014.<br>Background: The national HAART programme in South Africa was launched in April 2004. Highly Active Antiretroviral Therapy (HAART) is the medication that slows down the progression from HIV to AIDS, while it had been introduced in Western countries in 1996. Adherence to ART is the major factor in ensuring the virologic success of an initial regimen and is a significant determinant of survival for HIV-infected patients with the wild type virus who are on highly active antiretroviral treatment. Patients with suboptimal adherence are at risk, not o

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35

Martiny, Delphine. "Contribution of MALDI-TOF mass spectrometry in the microbiological diagnosis and clinical management of patients suffering from infectious diseases." Doctoral thesis, Universite Libre de Bruxelles, 2013. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209372.

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In infected patients, the rapid identification of pathogens is critical. After a long period of slow technological improvement, the microbiology laboratory is now undergoing significant evolution. This work evaluated the contribution of recent MALDI-TOF MS technology in terms of the diagnosis and clinical management of patients and its implementation in the laboratory of tomorrow. The studies were conducted over a 3.5-year period, mostly in the iris public hospital network of Brussels. <p>First, we confirmed the accurate performance of MALDI-TOF MS in the identification of routine isolates, re

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Mathiba, Olorato P. "An Oral Health Survey among HIV-infected children younger than twelve years of age presenting at the Paediatric Infectious Diseases Clinic at Tygerberg Hospital." The University of the Western Cape, 2017. http://hdl.handle.net/11394/5531.

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Magister Scientiae Dentium - MSc(Dent)<br>HIV/AIDS remains a global health problem. Orofacial manifestations of HIV/AIDS have been found to be among the first signs of immune suppression and have been used in the clini-cal staging of the disease. Infants and children are prone to opportunistic infections because of the immature immune system. Orofacial manifestations of HIV can therefore be used to predict prog-nosis and progression of infection. The introduction of highly active anti-retroviral therapy (HAART) has since seen a decline in the development of opportunistic infections and HIV-rel

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Hlela, Carol. "Human T-lymphotropic virus type 1(HTLV-1) associated infective dermatitis." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:48d8069a-9bd3-4cdc-9474-8246564c03e8.

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Human T lymphotropic virus type -1 (HTLV-1) infections are important causes of mortality and morbidity in endemic areas worldwide. There is neither a vaccine specific for the virus nor satisfactory treatment for the associated malignancy or inflammatory syndromes. HTLV-1 associated infective dermatitis (IDH) is a chronic dermatitis that has been observed in a variable proportion of HTLV-1 infected children. IDH may serve as an early clinical marker for HTLV-1 and an indicator of increased risk for developing other HTLV-1 associated conditions such as adult T cell leukaemia/lymphoma (ATLL) and

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Pelegrín, Senent Iván. "Clinical approach and management of bacterial infections of the central nervous system related to hydrocephalus." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/585886.

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INTRODUCTION: Community-acquired bacterial meningitis is a relevant entity related to a high morbidity and mortality, despite of the adjuvant and antibiotic treatments available. Morbidity and mortality are caused by neurological complications, being hydrocephalus one of the less investigated one and related to Listeria monocytogenes meningoencephalitis episodes, which increase have been reported in the last decade. Moreover, the devices used for treatment of hydrocephalus have a high risk of infection. These infections have a high personal and economic costs, and their prevention and treatme

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Wong, Hei Sunny. "Genetic susceptibility to common mycobacterial diseases." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:cb4dd818-4693-4168-ad8a-cdeb59e2d5f3.

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Common mycobacterial diseases, including tuberculosis and leprosy, contribute to major mortality and morbidity worldwide. Despite evidence of an important role of host genetic factors in susceptibility to these infections, few compelling genetic associations have been identified with previous candidate gene and linkage approaches. This thesis investigates the genetic factors of human immunity to these mycobacterial diseases using a high-throughput approach of association testing. To assess genetic susceptibility to tuberculosis, I have conducted a genome-wide association study in the Gambian p

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Brumme, Chanson Joachim. "Tools and applications for DNA sequencing in the clinical management of viral infectious diseases : examples from HIV-1 and HCV." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/54775.

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Combination antiretroviral therapy has transformed Human Immunodeficiency Virus (HIV) infection from what was once a fatal diagnosis to a manageable chronic condition. Similarly, new direct-acting antivirals offer a potential cure for individuals infected with Hepatitis C Virus (HCV). Treatment of these two infectious diseases is now routinely guided by genotypic drug resistance testing: portions of the viral genome are sequenced and analyzed for mutations in order to select drug combinations best suited to treat each individual’s unique viral population. The primary aim of this thesis is to d

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Seale, Anna Catherine. "The clinical and molecular epidemiology of Streptococcus agalactiae in Kenya : maternal colonisation and perinatal outcomes." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:6e7d952a-dc5b-4af0-b0bb-f2ae2184eed0.

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Johnson, Colin Wolcott. "Comparative Susceptibility and Mechanisms of Resistance to Host Defense Peptides in Daptomycin-Susceptible and Non-Susceptible Clinical Isolates of Staphylococcus aureus." Scholarship @ Claremont, 2016. http://scholarship.claremont.edu/cmc_theses/1303.

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Host defense peptides (HDPs) provide innate immune defense against invasive S. aureus infection. Recent studies suggest potential cross-resistance between HDPs and the lipopeptide antibiotic, daptomycin (DAP). Isolates that exhibit DAP non-susceptible phenotypes may have virulence advantages and pose challenges to effective treatment. The current studies were performed to compare the efficacies and mechanisms of action of native and engineered HDPs vs. clinical S. aureus strain pairs which differed in susceptibility to daptomycin in vitro. Ultrasensitive radial diffusion and multi-colored flow

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Thornton, Susan. "A portfolio of study practice and research : psychological variables and HIV infection; a study of their effect on disease progression among long term infected individuals." Thesis, University of Surrey, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362328.

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Eyre, David William. "Quantitative study of Clostridium difficile transmission using extensive epidemiological data and whole genome sequencing." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:a7197605-6da6-4dbc-9bec-171d6e683eb1.

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Clostridium difficile is a leading healthcare-associated infection, which causes diarrhoea, and is almost exclusively precipitated by antibiotic exposure. Traditionally C. difficile infection (CDI) has been considered predominantly transmitted within hospitals. However, endemic spread hampers identification of the source of infections, and therefore control and prevention of disease. A cohort of consecutive hospital and community CDI cases in Oxfordshire from September 2007 to March 2011 was investigated. For each case hospital admission, ward movement and demographic data were available allow

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Keene, Christopher Dale. "Guided imagery as a psychoneuroimmunological intervention for HIV-positive individuals." W&M ScholarWorks, 1996. https://scholarworks.wm.edu/etd/1539618578.

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Ghosh, Sthitodhi. "A Mobile Healthcare (mHEALTH) System Using Polymer Lab-On-A-Chip With Chemiluminescence Based High-Sensitive Immunoassay For Clinical Diagnostics." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1592170905649462.

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Humphreys, Isla Sheree. "Host and viral factors that determine the clinical outcome of hepatitis C virus genotype 3a infection." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:efe4f97b-5f82-4e8a-8ed5-18b71c5f00db.

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HCV infects 170 million persons worldwide and is a serious global health problem. Genotype-3a is the dominant genotype in newly diagnosed infections within the UK and has a high response rate to interferon therapy, with up to 70% patients achieving a sustained virological response (SVR). The reason(s) for this are unknown; therefore the aim was to assess host and viral factors that determine treatment outcome of subtype-3a infection. Full-length subtype-3a viral sequence analysis identified 2 novel regions of hypervariability within E2 - HVR495 and HVR575, that are subject to positive selectio

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Wang, Linghang. "Killer immunoglobulin-like receptor polymorphism in a Chinese HIV-1 infection cohort." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:9c1d0fb9-21b0-4123-995d-6bd5ae3e094f.

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Genetic and functional studies have demonstrated that KIR gene polymorphism, including different haplotypes, allelic polymorphisms and different expression levels of KIRs, may all play a part in the association with HIV-1 infection outcome. Currently, there are very few studies focusing on the association between KIR and HIV in the Chinese population. In this project, we started to look at the polymorphism of KIRs in a unique chronic HIV-1 infected cohort (SM cohort), evaluating the impact of KIR and KIR-HLA interactions in terms of HIV-1 infection progression. The SM cohort is unique because

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Shinkins, Bethany. "The evaluation and expansion of methodologies relating to the reporting and analyses of intermediate test results : improving the clinical utility of diagnostic research." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:2df7fc16-51f5-4978-80bd-b69efdf9c8a2.

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<b>Background and objectives:</b> It has been argued that the binary framework frequently adopted to analyse test accuracy does not represent the clinical reality of diagnostic practice, and the recognition of an intermediate category of test result could make the utility of diagnostic tests more transparent. The objective of this thesis is to explore the value of moving away from the binary framework when evaluating and interpreting quantitative diagnostic tests. <b>Methods:</b> This thesis starts with an overview of the key arguments against dichotomising quantitative test results and a summ

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Ramoshaba, Refilwe. "Barriers influencing the use of prevention of mother-to-child transmission of Human Immunodeficiency Virus follow-up services at Mankweng Clinics." Thesis, University of Limpopo, 2017. http://hdl.handle.net/10386/2009.

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