Journal articles: 'Infectious disease research'

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Head, M. "Infectious Disease Research Network." Journal of Antimicrobial Chemotherapy 64, Supplement 1 (August 12, 2009): i25—i27. http://dx.doi.org/10.1093/jac/dkp259.

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Lou, Zhiyong. "Infectious Disease Research in China." ACS Infectious Diseases 6, no. 5 (April 24, 2020): 760. http://dx.doi.org/10.1021/acsinfecdis.0c00220.

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Dove, Alan. "New infectious disease research funding." Nature Medicine 4, no. 12 (December 1998): 1350. http://dx.doi.org/10.1038/3932.

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ICHINOSE, Yoshio. "Kenya Research Station and Viral Infectious Disease Research." Uirusu 63, no. 1 (2013): 75–78. http://dx.doi.org/10.2222/jsv.63.75.

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Dorrell, Sharon. "International grants for infectious disease research." Molecular Medicine Today 5, no. 8 (August 1999): 327. http://dx.doi.org/10.1016/s1357-4310(99)01533-6.

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Tramont, Edmund C., and Arthur L. Kellermann. "The Infectious Disease Clinical Research Program." Military Medicine 184, Supplement_2 (November 1, 2019): 1–2. http://dx.doi.org/10.1093/milmed/usz344.

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Layne, Scott P., and Tony J. Beugelsdijk. "Laboratory firepower for infectious disease research." Nature Biotechnology 16, no. 9 (September 1998): 825–29. http://dx.doi.org/10.1038/nbt0998-825.

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Sarkar, Anjali A. "Top Protocols in Infectious Disease Research." Genetic Engineering & Biotechnology News 41, P1 (September 1, 2021): P40—P42. http://dx.doi.org/10.1089/gen.41.p1.14.

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Shinoda, Sumio. "Special Issue on Infectious Disease Control in SATREPS Projects." Journal of Disaster Research 13, no. 4 (August 1, 2018): 733–34. http://dx.doi.org/10.20965/jdr.2018.p0733.

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The Science and Technology Research Partnership for Sustainable Development (SATREPS) is a Japanese government program that promotes international joint research. The program is structured as a collaboration between the Japan Science and Technology Agency (JST) and the Japan International Cooperation Agency (JICA). The program includes various fields, such as Environment and Energy, Bioresources, Disaster Prevention and Mitigation, and Infectious Disease Control, and a total 52 projects were currently in progress as of May, 2018. It is expected that the promotion of international joint research under this program will enable Japanese research institutions to conduct research more effectively in fields and having targets that make it advantageous to do that research in developing countries, including countries in Latin America and the Caribbean, Asia, and Africa. Recently, SATREPS projects in the field of Infectious Disease have been but under the control of the Japan Agency for Medical Research and Development (AMED). Although adult maladies, such as malignant tumors, heart disease, and cerebral apoplexy, are major causes of death in the developed countries including Japan, infectious diseases are still responsible for the high mortality rates in developing countries. Therefore, Infectious Disease Control is the important field of SATREPS. Infectious Disease Control projects are progressing in several countries, including Kenya, Zambia, Bangladesh, the Philippines, and Brazil, and various infectious diseases and pathogens have been targeted. In this special issue on Infectious Disease Control, the following reports from three projects have been selected: “The JICA-AMED SATREPS Project to Control Outbreaks of Yellow Fever and Rift Valley Fever in Kenya” by Nagasaki University, “Comprehensive Etiological and Epidemiological Study on Acute Respiratory Infections in Children in the Philippines” by Tohoku University, and “International Joint Research on Antifungal Resistant Fungi in Brazil” by Chiba University. These projects include viral, bacterial, and fungal infections. If they become available, further supplementary reports from other projects in this field will be published in a future issue.

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Hamburg, Margaret A. "Considerations for infectious disease research and practice." Technology in Society 30, no. 3-4 (August 2008): 383–87. http://dx.doi.org/10.1016/j.techsoc.2008.04.002.

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Johnson, P. T. J., J. C. de Roode, and A. Fenton. "Why infectious disease research needs community ecology." Science 349, no. 6252 (September 3, 2015): 1259504. http://dx.doi.org/10.1126/science.1259504.

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Jia, Peng, Weihua Dong, Shujuan Yang, Zhicheng Zhan, La Tu, and Shengjie Lai. "Spatial Lifecourse Epidemiology and Infectious Disease Research." Trends in Parasitology 36, no. 3 (March 2020): 235–38. http://dx.doi.org/10.1016/j.pt.2019.12.012.

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Burgess, Timothy H., and David Tribble. "The Infectious Disease Clinical Research Program: Overview." Military Medicine 184, Supplement_2 (November 1, 2019): 3–5. http://dx.doi.org/10.1093/milmed/usz338.

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Burgess, Timothy H., and David Tribble. "Infectious Disease Clinical Research Program: Future Direction." Military Medicine 184, Supplement_2 (November 1, 2019): 71. http://dx.doi.org/10.1093/milmed/usz339.

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Furuse, Yuki. "Analysis of research intensity on infectious disease by disease burden reveals which infectious diseases are neglected by researchers." Proceedings of the National Academy of Sciences 116, no. 2 (December 31, 2018): 478–83. http://dx.doi.org/10.1073/pnas.1814484116.

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Infectious diseases are associated with considerable morbidity and mortality worldwide. Although human, financial, substantial, and time resources are limited, it is unknown whether such resources are used effectively in research to manage diseases. The correlation between the disability-adjusted life years to represent disease burden and number of publications as a surrogate for research activity was investigated to measure burden-adjusted research intensity for 52 infectious diseases at global and country levels. There was significantly low research intensity for paratyphoid fever and high intensity for influenza, HIV/acquired immunodeficiency syndrome, hepatitis C, and tuberculosis considering their disease burden. We identified the infectious diseases that have received the most attention from researchers and those that have been relatively disregarded. Interestingly, not all so-called neglected tropical diseases were subject to low burden-adjusted research intensity. Analysis of the intensity of infectious disease research at a country level revealed characteristic patterns. These findings provided a basis for further discussion of the more appropriate allocation of resources for research into infectious diseases.

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Coles, Christian, and Martin G. Ottolini. "Infectious Disease Clinical Research Program: Building the Bench." Military Medicine 184, Supplement_2 (November 1, 2019): 66–70. http://dx.doi.org/10.1093/milmed/usz094.

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ABSTRACT The role of physicians in the U.S. Armed Forces is diverse, encompassing a wide array of skills and responsibilities to provide superior healthcare to their patients and to advance military medicine. In addition to healthcare delivery and medical education, military physicians are engaged in public health, operational medicine, and cutting-edge medical research. Thus, clinical research is a crucial component of Graduate Medical Education (GME) and supports critical thinking (knowledge, skills, and abilities) and the development of leadership skills among U.S. military physicians. The Infectious Disease Clinical Research Program (IDCRP) education mission was established in 2005 with the overall goal of supporting the development and training of the next generation of clinical researchers in infectious diseases and related public health disciplines in the Armed Forces using several strategies, including didactic learning, mentored research, and research engagement. Through involvement in the IDCRP, infectious disease fellows, residents (e.g., surgical, internal medicine, and pediatrics), and Master of Public Health (MPH) students have continued their education and gained valuable skills related to clinical research. Trainees either conduct research with IDCRP mentors or participate in IDCRP-led practicum experiences, with research projects ranging from epidemiologic studies to microbiological assessments. Consistent with the needs of the Military Health System (MHS), and in accordance with Accreditation Council for Graduate Medical Education goals, the IDCRP provides opportunities for medical and graduate students, residents, and infectious disease fellows to conduct mentored research within the MHS, as well as gain important leadership skills in the conduct of clinical research. Overall, IDCRP continues to further infectious disease research through the support and education of the next generation of active-duty infectious disease researchers in the MHS.

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Forman, D. "Stomach cancer - an infectious disease?" European Journal of Cancer 37 (April 2001): S248. http://dx.doi.org/10.1016/s0959-8049(01)81408-8.

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Lalani, Tahaniyat, Jamie Fraser, Mark S. Riddle, Ramiro L. Gutierrez, Patrick W. Hickey, and David R. Tribble. "Deployment Infectious Disease Threats: IDCRP Initiatives and Vision Forward." Military Medicine 184, Supplement_2 (November 1, 2019): 26–34. http://dx.doi.org/10.1093/milmed/usz182.

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Abstract Background Infectious diseases pose a significant threat to health and readiness of military personnel deployed globally during wartime and peacekeeping activities. Surveillance and improvement in mitigation through research of infectious disease threats remain an integral part of Force Health Protection. Herein, we review research efforts of the Infectious Disease Clinical Research Program related to deployment and travel-related infections. Methods The objectives of the Deployment and Travel-Related Infections Research Area are to (1) provide epidemiologic and clinical data, including pathogen-specific estimates of disease incidence among deployed troops, (2) execute clinical trials and effectiveness studies to improve recommendations regarding prevention and treatment of infections during deployment, and (3) evaluate the knowledge and practice patterns of health care providers engaged in deployment/travel medicine and the impact on outcomes. The centerpiece protocol of the research area is the Deployment and Travel-Related Infectious Disease Risk Assessment, Outcomes, and Prevention Strategies cohort study (TravMil), which was initiated in 2010 and collects data on a broad range of deployment-related infections. Results To date, 4,154 deployed military personnel and traveling Department of Defense (DoD) beneficiaries have been enrolled in TravMil. Surveillance data collected through the TravMil study provide assessment of deployment and travel-related infectious disease threats, and the effectiveness of mitigation strategies. The incidence of travelers’ diarrhea, influenza-like illness, and undifferentiated febrile illness is 20.48%, 9.34%, and 6.16%, respectively. The cohort study also provides necessary infrastructure to execute clinical trials. The TrEAT TD clinical trial evaluated the effectiveness of single-dose antibiotic therapy for travelers’ diarrhea in the deployed setting. When compared to levofloxacin, azithromycin was not inferior; however, inferiority was not demonstrated with use of single dose of rifaximin. The trial findings supported the development of a deployment-related health guideline for the management of acute diarrheal disease. A clinical trial evaluating the effectiveness of rifaximin for prevention for travelers’ diarrhea (Prevent TD) is underway. Conclusions The research area has proven its ability to conduct impactful research, including the development of field-expedient diagnostics, the largest DoD multi-site travelers’ diarrhea randomized control trial in peacetime and combat settings, and informed Force Health Protection guidance. The research area continues to provide surveillance data to military commands via an established collaborative network of military treatment facilities, DoD laboratories (both within and outside the continental United States), foreign militaries, and academia. The conduct of clinical and translational research in a deployment setting presents significant challenges, most notably in recruitment/enrollment and compliance with study-related procedures during deployment.

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Tanzi, Maria G. "Infectious disease research: C. difficile, antibiotic stewardship, HIV." Pharmacy Today 21, no. 1 (January 2015): 26–27. http://dx.doi.org/10.1016/s1042-0991(15)30535-1.

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Carter, Tim. "Seafarers and infectious disease – Directions for future research." Travel Medicine and Infectious Disease 11, no. 4 (July 2013): 259–60. http://dx.doi.org/10.1016/j.tmaid.2013.03.012.

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Gaddy, Hampton Gray. "Using local knowledge in emerging infectious disease research." Social Science & Medicine 258 (August 2020): 113107. http://dx.doi.org/10.1016/j.socscimed.2020.113107.

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Olesen, Ole F., and Marit Ackermann. "Increasing European Support for Neglected Infectious Disease Research." Computational and Structural Biotechnology Journal 15 (2017): 180–84. http://dx.doi.org/10.1016/j.csbj.2017.01.007.

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Laketa, Vibor. "Microscopy in Infectious Disease Research—Imaging Across Scales." Journal of Molecular Biology 430, no. 17 (August 2018): 2612–25. http://dx.doi.org/10.1016/j.jmb.2018.06.018.

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Geissner, Andreas, Chakkumkal Anish, and Peter H. Seeberger. "Glycan arrays as tools for infectious disease research." Current Opinion in Chemical Biology 18 (February 2014): 38–45. http://dx.doi.org/10.1016/j.cbpa.2013.11.013.

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Shirakawa, Toshiro, Kazufumi Shimizu, Takako Utsumi, Masanori Kameoka, Hak Hotta, and Yoshitake Hayashi. "Indonesia-Kobe University Collaborative Research Center for Emerging and Reemerging Infectious Diseases (CRC-ERID) J-GRID (Japan Initiative for Global Research Network on Infectious Diseases)." Journal of Disaster Research 9, no. 5 (October 1, 2014): 828–35. http://dx.doi.org/10.20965/jdr.2014.p0828.

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The Center for Infectious Diseases (CID), Kobe University Graduate School of Medicine, has led an Asia-related medical research program for over 50 years. The Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) established the Indonesia-Kobe University Collaborative Research Center for Emerging and Reemerging Infectious Diseases (CRC-FRID), which is staffed by Japanese researchers from the CID, Kobe University Graduate School of Medicine, and Indonesian researchers from the Institute of Tropical Disease (ITD) of Airlangga University, Surabaya, Indonesia. There they focus on five disease types – influenza, infectious hepatitis, dengue fever, HIV/AIDS, and infectious diarrheal diseases – in collaborative research. This paper summarizes research results for these 5 diseases as published in previous papers.

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Bai, Lu, and Wenlong He. "Research progress on human microecology and infectious diseases." Infection International 7, no. 3 (September 30, 2018): 94–100. http://dx.doi.org/10.2478/ii-2018-0027.

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AbstractHuman microecology has been extensively investigated. Similar to an important physiologically functioning organ of the human body, the microecological system is one of the leading systems for environmental survival, health, genetics, disease, and aging. It is also an essential carrier for drug metabolism and microbial resistance. The occurrence, development, and deterioration of many infectious diseases are closely related to human microecological systems. This study mainly focuses on the changes in microbial groups associated with various infectious diseases to explore the relevant role of human microecology in the development of infectious diseases and its breakthrough implications in future accurate treatments of infectious diseases.

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Saijo, Masayuki. "Dual Use Research of Concern Issues in the Field of Microbiology Research in Japan." Journal of Disaster Research 8, no. 4 (August 1, 2013): 693–97. http://dx.doi.org/10.20965/jdr.2013.p0693.

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Microbiology researches and infectious disease researches have to contribute to the progress of science and contribute to measures against infectious disease burdens. However, researches on infectious diseases and microbiology always have a potential risk related to scientific ambiguity, i.e., so-called Dual Use Research of Concern (DURC). Most of microbiologist, now trying to improve the level of biosafety and biosecurity, will be required to also improve their consciousness about DURC and pay attention to trends of domestic and international DURC issues in the field of microbiology and properly cope with them. When making plans, applying for research funding, and publicizing research outcomes, researchers are required to also care about DURC. To set up such system, discussions need to be made also at research institutes, including the National Institute of Infectious Diseases, over DURC issues, such as how to educate the researchers and how to cope with DURC.

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Lanteri, Charlotte, Katrin Mende, and Mark Kortepeter. "Emerging Infectious Diseases and Antimicrobial Resistance (EIDAR)." Military Medicine 184, Supplement_2 (April 20, 2019): 59–65. http://dx.doi.org/10.1093/milmed/usz081.

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Abstract Introduction The Infectious Disease Clinical Research Program’s (IDCRP) Emerging Infectious Diseases and Antimicrobial Resistance (EIDAR) Research Area is a Department of Defense (DoD) clinical research capability that is responsive and adaptive to emerging infectious disease (EID) threats to US military readiness. Among active-duty and other Military Health System (MHS) beneficiaries, EIDAR research is largely focused on evaluating the incidence, risk factors, and acute- and long-term health effects of military-relevant EIDs, especially those caused by high-consequence pathogens or are responsible for outbreaks among US military populations. The EIDAR efforts also address Force Health Protection concerns associated with antimicrobial resistance and antimicrobial stewardship practices within the MHS. Methods The EIDAR studies utilize the approach of: (1) Preparing for emergent conditions to systematically collect clinical specimens and data and conduct clinical trials to assist the military with a scientifically appropriate response; and (2) Evaluating burden of emergent military-relevant infectious diseases and assessing risks for exposure and development of post-infectious complications and overall impact on military readiness. Results In response to the Ebola virus epidemic in West Africa, the IDCRP partnered with the National Institutes of Health in developing a multicenter, randomized safety and efficacy study of investigational therapeutics in Ebola patients. Subsequently, the EIDAR team developed a protocol to serve as a contingency plan (EpICC-EID) to allow clinical research activities to occur during future outbreaks of viral hemorrhagic fever and severe acute respiratory infections among MHS patients. The EIDAR portfolio recently expanded to include studies to understand exposure risks and impact on military readiness for a diversity of EIDs, such as seroincidence of non-Lyme disease borreliosis and Coccidioides fungal infections among high-risk military populations. The team also launched a new prospective study in response to the recent Zika epidemic to conduct surveillance for Zika and other related viruses among MHS beneficiaries in Puerto Rico. Another new study will prospectively follow U.S. Marines via an online health assessment survey to assess long-term health effects following the largest DoD Shiga Toxin-Producing Escherichia coli outbreak at the U.S. Marine Corps Recruit Depot-San Diego. In cooperation with the Trauma-Related Infections Research Area, the EIDAR Research Area is also involved with the Multidrug-Resistant and Virulent Organisms Trauma Infections Initiative, which is a collaborative effort across DoD laboratories to characterize bacterial and fungal isolates infecting combat-related extremity wounds and link lab findings to clinical outcomes. Furthermore, the EIDAR team has developed an Antimicrobial Resistance and Stewardship Collaborative Clinical Research Consortium, comprised of Infectious Disease and Pharmacy specialists. Conclusions The EIDAR Research Area is responsive to military-relevant infectious disease threats that are also frequently global public health concerns. Several new EIDAR efforts are underway that will provide Combatant Command Surgeons, Infectious Diseases Service Chiefs, and other Force Health Protection stakeholders with epidemiological information to mitigate the impact of EIDs and antimicrobial resistance on the health of U.S. military service members and their dependents.

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Seneviratne, Chaminda Jayampath, and Tanujaa Suriyanarayanan. "Microbiomics of Oral Biofilms: Driving The Future of Dental Research." Scientific Dental Journal 1, no. 1 (September 28, 2017): 25. http://dx.doi.org/10.26912/sdj.v1i1.2089.

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<p>Oral infectious diseases such as dental caries, periodontal disease, endodontic infections, oral candidiasis and peri-implantitis cause major health problems worldwide. All of these infectious diseases are associated with the biofilm growth mode of the oral pathogens. In the past, researchers often attempted to examine the association of single pathogens with particular dental diseases such as in the case of <em>Streptococcus mutans</em> acting as an aetiological agent for dental caries and the so-called “red-complex” bacteria for periodontal disease. However, with the recent advent of OMICS biology techniques such as genomics, transcriptomics, proteomics, it is possible to gain new insights into the host-microbial interaction, microbial community structure and composition in the oral cavity. The new studies on oral microbiomics can unravel the facets of the aetiopathology of oral diseases as never seen before. This mini-review will provide an history and overview of some of the existing DNA sequencing platforms employed to study the microbiomics of oral biofilms and the exciting future ahead for dental research.</p>

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Wertheim, Heiman F. L., Pilaipan Puthavathana, Ngoc My Nghiem, H. Rogier van Doorn, Trung Vu Nguyen, Hung Viet Pham, Decy Subekti, et al. "Laboratory Capacity Building in Asia for Infectious Disease Research: Experiences from the South East Asia Infectious Disease Clinical Research Network (SEAICRN)." PLoS Medicine 7, no. 4 (April 6, 2010): e1000231. http://dx.doi.org/10.1371/journal.pmed.1000231.

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Shinoda, Sumio. "Special Issue on J-GRID (Japan Initiative for Global Research Network on Infectious Disease)." Journal of Disaster Research 9, no. 5 (October 1, 2014): 765–67. http://dx.doi.org/10.20965/jdr.2014.p0765.

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In the developed countries including Japan, malignant tumor (cancer), heart disease and cerebral apoplexy are major causes of death, but infectious diseases still responsible for high mortality in the developing countries, especially for children less than 5 years of age. World Health Statistics published byWHO indicates a high percentage of mortality from infectious diseases such as HIV/AIDS, diarrhea, measles, malaria and pneumonia in children of South and Southeast Asian and African countries (World Health Statistics 2014,World Health Organization). Many of these infectious diseases have the potential for borderless transmission and invasion to Japan. Given this situation, Japan’s Ministry of Education, Culture, Sports, Science and Technology (MEXT) introduced Phase I of a program “Founding Research Centers for Emerging and Reemerging Infectious Diseases,” running from fiscal 2005 to 2009 and involving 8 Japanese universities and 2 Japanese research centers. The program was established to: 1) Create of a domestic research structure to promote the accumulation of fundamental knowledge about infectious diseases, 2) Set up 13 overseas research collaboration centers in 8 countries at high risk of emerging and reemerging infections, Japanese researchers are stationed at these centers, where they conduct research in partnership with overseas instructors, 3) Develop a network among domestic and overseas research centers, 4) Develop human resources. The program, supervised by MEXT, and managed by the RIKEN Center of the Research Network for Infectious Diseases (Riken CRNID). Dr. Yoshiyuki Nagai, Program Director (PD), heads CRNID and is organizing the program. Phase II of the program was set up as the Japan Initiative for the Global Research Network on Infectious Diseases (J-GRID) and was established for fiscal 2010-2014. Participating universities, institutes and countries in J-GRID are as follows: Hokkaido University : Zambia Tohoku University : Philippines The University of Tokyo : China Tokyo Medical and Dental University : Ghana Osaka University : Thailand Kobe University : Indonesia Okayama University : India Nagasaki University : Vietnam Kenya (Associate*) Niigata University : Myanmar (Associate*) National Center for Global Health and Medicine : Vietnam National Institute of Animal Health : Thailand *Two associate members were involved in 2011. Each university and institute set up its collaborative research center in a country and conducts research on infectious diseases, especially typical regional diseases. The program’s outcome of each collaborative center is announced by the publication of various research papers or outreach programs, such as open lectures for citizens, and so on. The Asian-African Research Forum (AARF) on Infectious Disease organized by J-GRID is dedicated to reporting and discussing the research results of the collaborative research centers. Details and activities of J-GRID can be seen at http://www.crnid.riken.jp/jgrid/. The Figs. 1 and 2 show examples of the home page indicating the countries and the collaborative research institutes involved. J-GRID publishes the magazine entitled “Monthly CRNID,” which is available by mail upon request to “https://krs.bz/crnid/m?f=2&m=1110&t=8cdk&v=076691d2.” This publication contains various topical information on infectious diseases, such as research papers, newly announced news from WHO, overseas trip news, domestic infections, new drug developments, explanations, events, etc. Phase II will terminate on March 2015 (the end of FY 2014), and Phase III will begin in April 2015 at the start of the new FY. This special issue on J-GRID is being edited on the occasion of the final year of Phase II. The outlines of J-GRID and those of all the collaborative research centers are reviewed by Dr. Nagai, PD of CRNID, and the representatives of each respective collaborative center in this issue. Finally, I extend my sincere thanks to all authors and reviewers involved in this special issue.

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Rowley, Anne H. "Finding the Cause of Kawasaki Disease: A Pediatric Infectious Diseases Research Priority." Journal of Infectious Diseases 194, no. 12 (December 15, 2006): 1635–37. http://dx.doi.org/10.1086/509514.

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de Rooij, Doret, Evelien Belfroid, Renske Eilers, Dorothee Roßkamp, Corien Swaan, and Aura Timen. "Qualitative Research: Institutional Preparedness During Threats of Infectious Disease Outbreaks." BioMed Research International 2020 (January 23, 2020): 1–10. http://dx.doi.org/10.1155/2020/5861894.

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Background. As demonstrated during the global Ebola crisis of 2014–2016, healthcare institutions in high resource settings need support concerning preparedness during threats of infectious disease outbreaks. This study aimed to exploratively develop a standardized preparedness system to use during unfolding threats of severe infectious diseases. Methods. A qualitative three-step study among infectious disease prevention and control experts was performed. First, interviews (n=5) were conducted to identify which factors trigger preparedness activities during an unfolding threat. Second, these triggers informed the design of a phased preparedness system which was tested in a focus group discussion (n=11). Here preparedness activities per phase and per healthcare institution were identified. Third, the preparedness system was completed and verified in individual interviews (n=3). Interviews and the focus group were recorded, transcribed, and coded for emerging themes by two researchers independently. Data were analyzed using content analysis. Results. Four preparedness phases were identified: preparedness phase green is a situation without the presence of the infectious disease threat that requires centralized care, anywhere in the world. Phase yellow is an outbreak in the world with some likelihood of imported cases. Phase orange is a realistic chance of an unexpected case within the country, or unrest developing among population or staff; phase red is cases admitted to hospitals in the country, potentially causing a shortage of resources. Specific preparedness activities included infection prevention, diagnostics, patient care, staff, and communication. Consensus was reached on the need for the development of a preparedness system and national coordination during threats. Conclusions. In this study, we developed a standardized system to support institutional preparedness during an increasing threat. Use of this system by both curative healthcare institutions and the (municipal) public health service, could help to effectively communicate and align preparedness activities during future threats of severe infectious diseases.

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Heinrich, Kristina, Martin Bach, and Lutz Breuer. "Infectious Disease Research—What Role Is There for Hydrologists?" Journal of Water Resource and Protection 09, no. 02 (2017): 139–62. http://dx.doi.org/10.4236/jwarp.2017.92011.

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Ashraf, Haroon. "US infectious disease research leaders set out new priorities." Lancet Infectious Diseases 2, no. 11 (November 2002): 651. http://dx.doi.org/10.1016/s1473-3099(02)00427-9.

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Zhang, Ren, and Chun-Ting Zhang. "The impact of comparative genomics on infectious disease research." Microbes and Infection 8, no. 6 (May 2006): 1613–22. http://dx.doi.org/10.1016/j.micinf.2005.11.019.

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Gobat, Nina, John Amuasi, Yazdan Yazdanpanah, Louise Sigfid, Hugh Davies, John-Paul Byrne, Gail Carson, Christopher Butler, Alistair Nichol, and Herman Goossens. "Advancing preparedness for clinical research during infectious disease epidemics." ERJ Open Research 5, no. 2 (April 2019): 00227–2018. http://dx.doi.org/10.1183/23120541.00227-2018.

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Lee, Eric. "Survey and future research in immunology of infectious disease." Journal of Evolutionary Biology 16, no. 6 (November 2003): 1346. http://dx.doi.org/10.1046/j.1420-9101.2003.00580.x.

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Fitchett, Joseph R., Michael G. Head, and Rifat Atun. "Infectious disease research investments follow colonial ties: questionable ethics." International Health 6, no. 1 (January 23, 2014): 74–76. http://dx.doi.org/10.1093/inthealth/iht036.

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Swearengen, James R. "Choosing the right animal model for infectious disease research." Animal Models and Experimental Medicine 1, no. 2 (June 2018): 100–108. http://dx.doi.org/10.1002/ame2.12020.

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Walsh, Peter D. "A rant on infectious disease and ape research priorities." American Journal of Primatology 70, no. 8 (August 2008): 719–21. http://dx.doi.org/10.1002/ajp.20563.

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Hoffman, S. L. "INFECTIOUS DISEASE: Research (Genomics) Is Crucial to Attacking Malaria." Science 290, no. 5496 (November 24, 2000): 1509. http://dx.doi.org/10.1126/science.290.5496.1509.

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Tang, Mingsheng, Xinjun Mao, and Zahia Guessoum. "Research on an Infectious Disease Transmission by Flocking Birds." Scientific World Journal 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/196823.

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The swarm intelligence is becoming a hot topic. The flocking of birds is a natural phenomenon, which is formed and organized without central or external controls for some benefits (e.g., reduction of energy consummation). However, the flocking also has some negative effects on the human, as the infectious disease H7N9 will easily be transmited from the denser flocking birds to the human. Zombie-city model has been proposed to help analyzing and modeling the flocking birds and the artificial society. This paper focuses on the H7N9 virus transmission in the flocking birds and from the flocking birds to the human. And some interesting results have been shown: (1) only some simple rules could result in an emergence such as the flocking; (2) the minimum distance between birds could affect H7N9 virus transmission in the flocking birds and even affect the virus transmissions from the flocking birds to the human.

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Siva, Nayanah. "China to scale up collaborations in infectious disease research." Nature Medicine 16, no. 9 (September 2010): 938. http://dx.doi.org/10.1038/nm0910-938b.

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Kasson, Peter M. "Infectious Disease Research in the Era of Big Data." Annual Review of Biomedical Data Science 3, no. 1 (July 20, 2020): 43–59. http://dx.doi.org/10.1146/annurev-biodatasci-121219-025722.

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Infectious disease research spans scales from the molecular to the global—from specific mechanisms of pathogen drug resistance, virulence, and replication to the movement of people, animals, and pathogens around the world. All of these research areas have been impacted by the recent growth of large-scale data sources and data analytics. Some of these advances rely on data or analytic methods that are common to most biomedical data science, while others leverage the unique nature of infectious disease, namely its communicability. This review outlines major research progress in the past few years and highlights some remaining opportunities, focusing on data or methodological approaches particular to infectious disease.

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Holmes, Bev J. "Communicating about emerging infectious disease: The importance of research." Health, Risk & Society 10, no. 4 (August 2008): 349–60. http://dx.doi.org/10.1080/13698570802166431.

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Linard, Catherine, and Andrew J. Tatem. "Large-scale spatial population databases in infectious disease research." International Journal of Health Geographics 11, no. 1 (2012): 7. http://dx.doi.org/10.1186/1476-072x-11-7.

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Douros, Antonios, Christina Santella, Sophie Dell’Aniello, Laurent Azoulay, Christel Renoux, Samy Suissa, and Paul Brassard. "Infectious Disease Burden and the Risk of Alzheimer’s Disease: A Population-Based Study." Journal of Alzheimer's Disease 81, no. 1 (May 4, 2021): 329–38. http://dx.doi.org/10.3233/jad-201534.

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Background: Previous studies suggested a link between various infectious pathogens and the development of Alzheimer’s disease (AD), posing the question whether infectious disease could present a novel modifiable risk factor. Objective: To assess whether infectious disease burden due to clinically apparent infections is associated with an increased risk of AD. Methods: We conducted a population-based nested case-control study using the United Kingdom Clinical Practice Research Datalink. We included all dementia-free subjects ≥50 years of age enrolling in the database between January 1988 and December 2017. Each case of AD identified during follow-up was matched with up to 40 controls. Conditional logistic regression estimated adjusted odds ratios (ORs) with 95% confidence intervals (CIs) of AD associated with ≥1 infection diagnosed > 2 years before the index date compared with no infection during the study period. We further stratified by time since first infection and cumulative number of infections. Results: The cohort included overall 4,262,092 individuals (mean age at cohort entry 60.4 years; 52% female). During a median follow-up of 10.5 years, 40,455 cases of AD were matched to 1,610,502 controls. Compared with having no burden of infectious disease, having a burden of infectious disease was associated with an increase in the risk of AD (OR, 1.05; 95% CI, 1.02 to 1.08). The risk increased with longer time since first infection, peaking after 12–30 years (OR, 1.11; 95% CI, 1.05–1.17). The risk did not increase with cumulative number of infections. Conclusion: The overall risk of AD associated with infectious disease burden was small but increased gradually with longer time since first infection.

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Elfaituri, Muhammed Khaled, Sara Morsy, Gehad Mohamed Tawfik, Abdelaziz Abdelaal, Amr Ehab El-Qushayri, Hazem Abdelkarem Faraj, Truong Hong Hieu, and Nguyen Tien Huy. "Incidence of Infection-related mortality in cancer patients: Trend and survival analysis." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): e23095-e23095. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e23095.

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e23095 Background: Infectious diseases are the second leading cause of death in the field of oncology. Around 60% of deaths are infection related to cancer patients, especially with underlying hematological malignancies. This study assesses the changing trends of mortality in cancer patients from infectious causes in the past 40 years. Methods: This is a retrospective analysis on 151440 cancer patients who died from infectious causes between 1973 and 2014, identified in the Surveillance, Epidemiology, and End Results (SEER) Program database. Results: Pneumonia and influenza were the most common infections (n = 72133) followed by parasitic diseases and other infections (n = 47310) and septicemia (n = 31119), respectively. The average survival was 65.31 months, while pneumonia and influenza had the highest survival of all. Prostate cancer was the most common cancer associated with infectious diseases (n = 20068) followed by breast cancer (n = 16676) and Kaposi sarcoma (n = 13046), respectively. During 1998-2001, an overshoot in infection-related mortality was significantly noted (APC = 26.74%; 95%CI = 3.7:54.9). However, since 1973, the greatest reduction in infection-related mortality was recorded during 2012-2014 (APC = -37.15; 95%CI = -48.6: -23.2). Compared to other infectious diseases, ‘parasitic and other infections including HIV’ accounted for the highest incidence (SIR = 1.77; 95% CI = 1.69:1.84), where blood vessel tumors occurred the most in this category (SIR = 88.83; 95%CI = 2.25:494.9). Afterward, septicemia was the second most common infectious disease (SIR = 0.84; 95%CI = 0.81:0.88). Except for leukemia, lymphoma, plasma cell tumors, and mast cell tumors, hematologic tumors revealed the highest incidence of septicemia (SIR = 51.9; 95%CI = 1.31:289.16). Gender, race, marital status, an infectious organism, and tumor characteristics (behavior and grade); all accounted for significant differences in survival (P < 0.0001). The nomogram has outstanding discrimination ability (c-index = 0.85) with very minimal differences from the actual observations of 1-, 3-, and 5-year survival probabilities. Conclusions: Infection-related mortality in cancer patients declined from 1973 to 2014. The most common infections in cancer patients were Pneumonia and influenza, followed by parasitic diseases, other infections, and septicemia. Prostate cancer was the most common cancer associated with infectious diseases, followed by breast cancer and Kaposi sarcoma.

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Cooper, P. D. "Advances in disease vector research." International Journal for Parasitology 21, no. 2 (April 1991): 279. http://dx.doi.org/10.1016/0020-7519(91)90024-2.

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Journal articles on the topic 'Infectious disease research'

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