Relevant bibliographies by topics / "Inflammation" and "Myeloid derived Suppressor cells"

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic '"Inflammation" and "Myeloid derived Suppressor cells"'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic ""Inflammation" and "Myeloid derived Suppressor cells""

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Haverkamp., Jessica, and Timothy Ratliff. "Regulatory function of myeloid-derived suppressor cells is restricted to inflammatory site. (98.25)." Journal of Immunology 184, no. 1_Supplement (2010): 98.25. http://dx.doi.org/10.4049/jimmunol.184.supp.98.25.

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Abstract Myeloid-derived suppressor cells (MDSC) are identified in mice as Gr-1+CD11b+ cells able to suppress T cell proliferation. Suppressive function of MDSC is linked to expression of arginase I and inducible nitric oxide synthase (iNOS) and can be augmented by inflammation. While inflammation is linked to MDSC function, it is unknown if MDSC isolated from the inflammatory site possess equal regulatory function as those in distal sites such as the spleen. Using the POET-3 model of prostate inflammation, we show Gr-1+CD11b+ cells isolated from inflamed prostates express elevated levels of A
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Ostrand-Rosenberg, Suzanne, and Pratima Sinha. "Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer." Journal of Immunology 182, no. 8 (2009): 4499–506. http://dx.doi.org/10.4049/jimmunol.0802740.

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Wang, Dingzhi, and Raymond N. DuBois. "Myeloid-derived suppressor cells link inflammation to cancer." OncoImmunology 3, no. 5 (2014): e28581. http://dx.doi.org/10.4161/onci.28581.

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Chornoguz, Olesya, Lydia Grmail, Pratima Sinha, Konstantin Artemenko, Roman Zubarev, and Suzanne Ostrand-Rosenberg. "Inflammation-Induced Myeloid-Derived Suppressor Cells have enhanced resistance to apoptosis. (100.31)." Journal of Immunology 184, no. 1_Supplement (2010): 100.31. http://dx.doi.org/10.4049/jimmunol.184.supp.100.31.

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Abstract The purpose of this study is to deduce the influence of inflammation on apoptosis of Myeloid-Derived Suppressor cells. Myeloid-derived suppressor cells (MDSC) accumulate in patients and animals with cancer where they mediate systemic immune suppression. MDSC induced in heightened inflammatory environments with high levels of IL-1β and/or IL-6 accumulate more rapidly, are more potent suppressors of T cell activation, produce more IL-10, and have a greater ability to down-regulate macrophage production of IL-12, as compared to MDSC that develop in environments with lower levels of these
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Kusmartsev, Sergei, Elizabeth Kwenda, Paul R. Dominguez-Gutierrez, Paul L. Crispen, and Padraic O’Malley. "High Levels of PD-L1+ and Hyal2+ Myeloid-derived Suppressor Cells in Renal Cell Carcinoma." Journal of Kidney Cancer and VHL 9, no. 2 (2022): 1–6. http://dx.doi.org/10.15586/jkcvhl.v9i2.208.

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Renal cell carcinoma (RCC) patients frequently have increased number of immunosuppressive myeloid cells in circulation. High number of myeloid-derived suppressor cells (MDSCs) in the blood are associated with immune suppression as well as with cancer-related inflammation which drives the mobilization of myeloid cells to tumor tissue. Here, we show that peripheral blood from a previously untreated RCC patient has increased the number of monocytic CD33+CD11b+ MDSCs, which also co-expressed PD-L1 and membrane-bound enzyme hyaluronidase 2 (Hyal2). PD-L1 expression is associated with immune suppres
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Zhang, Hua, and Crystal Mackall. "Identifying an IDO-expressing “fibrocyte” subset of myeloid suppressor cells in pediatric cancer patients. (127.28)." Journal of Immunology 188, no. 1_Supplement (2012): 127.28. http://dx.doi.org/10.4049/jimmunol.188.supp.127.28.

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Abstract Human myeloid derived suppressor cells (MDSC) have been described as CD14-CD11b+CD33+HLADR- cells that exert T cell suppression via ROS, ARG1 and iNOS2. Here, we identify a novel myeloid suppressor subset, expanded in the peripheral blood of pediatric cancer patients, which is CD14-CD11b+CD33loHLADR+. Further analysis revealed that these abnormal myeloid cells were CD34+CD11chiIL4Rα+CD16+, and express α smooth muscle actin and collagen I/V on their surface, hallmarks of fibrocytes. The fibrocytes expressed high levels of indoleamine oxidase (IDO), and suppressed T cell proliferation i
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Kontaki, E., M. Ioannou, T. Alissafi, K. A. Papadakis, D. Boumpas, and P. Verginis. "Regulation of autoimmune inflammation by myeloid-derived suppressor cells." Annals of the Rheumatic Diseases 70, Suppl 2 (2011): A41—A42. http://dx.doi.org/10.1136/ard.2010.148973.14.

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Guan, Q., S. Moreno, C. Weiss, et al. "Myeloid Derived Suppressor Cells Attenuate Murine Allergic Airway Inflammation." Journal of Allergy and Clinical Immunology 129, no. 2 (2012): AB242. http://dx.doi.org/10.1016/j.jaci.2011.12.040.

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Ray, Prabir, Meenakshi Arora, Stephanie L. Poe, and Anuradha Ray. "Lung myeloid-derived suppressor cells and regulation of inflammation." Immunologic Research 50, no. 2-3 (2011): 153–58. http://dx.doi.org/10.1007/s12026-011-8230-1.

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Palumbo, Parrinello, Giallongo, et al. "Monocytic Myeloid Derived Suppressor Cells in Hematological Malignancies." International Journal of Molecular Sciences 20, no. 21 (2019): 5459. http://dx.doi.org/10.3390/ijms20215459.

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In the era of novel agents and immunotherapies in solid and liquid tumors, there is an emerging need to understand the cross-talk between the neoplastic cells, the host immune system, and the microenvironment to mitigate proliferation, survival, migration and resistance to drugs. In the microenvironment of hematological tumors there are cells belonging to the normal bone marrow, extracellular matrix proteins, adhesion molecules, cytokines, and growth factors produced by both stromal cells and neoplastic cells themselves. In this context, myeloid suppressor cells are an emerging sub-population
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Dissertations / Theses on the topic ""Inflammation" and "Myeloid derived Suppressor cells""

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Lotfi-Emran, Sahar. "Transformation of human mast cells by interferon-gamma and the potential role of myeloid derived suppressor cells in mastocytosis." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/4077.

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Mast cells respond to a variety of signals, are associated with both increased inflammation and regulation of the immune response, and are able to interact with a variety of hematopoietic and non-hematopoietic cells. The majority of the work that highlights mast cell pleiotropic abilities has been completed in murine models. Though these models have significantly advanced our understanding of what mast cells can do, they cannot inform us as to what mast cells actually do in human beings. The goal of this dissertation is to assess fully mature, primary human mast cell function beyond the well-d
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Bleve, Augusto. "Decoding of epigenetic and metabolic events driving immune diversion of myeloid cells in cancer." Doctoral thesis, Università del Piemonte Orientale, 2020. http://hdl.handle.net/11579/114772.

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Cancers induce ‘emergency’ hematopoiesis and expansion of myeloid-derived suppressor cells (MDSC) and tumor-associated macrophages (TAM), immunosuppressive and tumor-promoting cell populations, correlated with poor prognosis and resistance to chemo-immunotherapies. Molecular characterization of these cells offers new potential therapeutic opportunities. Previously, we showed that nuclear accumulation of p50 NF-kB transcription factor in TAM regulates expression of anti-inflammatory, pro-tumoral genes. Monocytic MDSC share myeloid progenitor and immunosuppressive properties with TAM. Here, we d
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Haverkamp, Jessica M. "Initiation and regulation of effector T cell responses in the prostate." Diss., University of Iowa, 2011. https://ir.uiowa.edu/etd/3311.

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Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells identified in mice as Gr-1+CD11b+ cells with the ability to inhibit T cell function. MDSC are emerging as important regulators of T cell mediated immune responses. Current paradigm suggests that despite heterogeneity, all Gr-1+CD11b+ cells are suppressive when exposed to inflammatory stimuli. In vitro evaluation shows MDSC from multiple tissue sites have suppressive activity, and in vivo inhibition of MDSCenhances T cell function. However, the relative capacity of MDSC present at localized inflamma
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Gerard, Claire. "Développement d’une stratégie thérapeutique immunosuppressive dérivée de cellules myéloïdes dans la maladie du greffon contre l’hôte." Thesis, Bourgogne Franche-Comté, 2020. https://nuxeo.u-bourgogne.fr/nuxeo/site/esupversions/a02d57d7-6368-477d-8e8d-0badac13bda0.

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Résumé :Notre équipe a développé une thérapie cellulaire originale dérivant de la lignée monocytaire. Cette sous-population de cellules humaines suppressives d’origine myéloide, appelée Human Monocyte-derived Suppressor Cells (HuMoSC, cellules CD33+), est capable d’inhiber la prolifération des lymphocytes T effecteurs et d’induire des CD4 et CD8 Treg. De plus, les HuMoSC préviennent l’apparition de la maladie du greffon contre l’hôte (GvHD).Dans un premier temps, nous avons montré qu’un environnement inflammatoire ou la présence d’immunosuppresseurs ne diminuaient pas la capacité des HuMoSC à
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Pyzer, Athalia Rachel. "Myeloid-derived suppressor cells in acute myeloid leukaemia." Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/36704.

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The tumour microenvironment consists of an immunosuppressive niche created by the complex interactions between cancer cells and surrounding stromal cells. A critical component of this environment are myeloid-derived suppressor cells (MDSCs), a heterogeneous group of immature myeloid cells arrested at different stages of differentiation and expanded in response to a variety of tumour factors. MDSCs exert diverse effects in modulating the interactions between immune effector cells and malignant cells. An increased presence of MDSCs is associated with tumour progression, poorer outcomes, and decr
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Mundy-Bosse, Bethany L. "Myeloid-Derived Suppressor Cells in Tumor Immunology." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1311261626.

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Dhakal, Santosh. "CHARACTERIZATION OF PORCINE MYELOID DERIVED SUPPRESSOR CELLS." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1437055804.

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VUERICH, Marta. "Extracellular ATP modulates Myeloid Derived Suppressor Cells functions." Doctoral thesis, Università degli studi di Ferrara, 2014. http://hdl.handle.net/11392/2389384.

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The main obstacle to the success of the immunotherapy is the well established tumor-induced tolerance. In 2007 a new cell population, Myeloid Derived Suppressor Cells (MDSCs), that accumulate under inflammatory conditions, especially in cancer, was identified. These cells are potent inhibitors of tumor immunity and are now considered a major contributor to the failure of the immunotherapy. Understanding the exact mechanism of immunosuppressive activity of MDSC is a crucial point in order to find new ways to improve anticancer therapies. In the last years several models of MDSC functions were
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Labrousse, Delphine. "Characterisation of myeloid-derived suppressor cells in chronic inflammatory diseases." Thesis, University of Southampton, 2010. https://eprints.soton.ac.uk/385140/.

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Sherger, Matthew George. "Identification of Myeloid Derived Suppressor Cells in Tumor Bearing Dogs." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1337617975.

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Books on the topic ""Inflammation" and "Myeloid derived Suppressor cells""

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Brandau, Sven, and Anca Dorhoi, eds. Myeloid-Derived Suppressor Cells. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1060-2.

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Escors, David, James E. Talmadge, Karine Breckpot, Jo A. Van Ginderachter, and Grazyna Kochan. Myeloid-Derived Suppressor Cells and Cancer. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26821-7.

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Brandau, Sven, and Anca Dorhoi. Myeloid-Derived Suppressor Cells. Humana Press, 2020.

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Jiménez-Cortegana, Carlos. Myeloid-Derived Suppressor Cells. Elsevier Science & Technology, 2023.

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Jiménez, Carlos, and Lorenzo Galluzzi. Myeloid-Derived Suppressor Cells. Elsevier Science & Technology Books, 2023.

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Brandau, Sven, and Anca Dorhoi. Myeloid-Derived Suppressor Cells. Springer, 2021.

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Jiménez-Cortegana, Carlos. Myeloid-Derived Suppressor Cells. Elsevier Science & Technology, 2024.

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Jiménez-Cortegana, Carlos. Myeloid-Derived Suppressor Cells. Elsevier Science & Technology Books, 2024.

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Talmadge, James E., David Escors, Karine Breckpot, Grazyna Kochan, and Jo A. Van Ginderachter. Myeloid-Derived Suppressor Cells and Cancer. Springer London, Limited, 2016.

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Talmadge, James E., David Escors, Karine Breckpot, Grazyna Kochan, and Jo A. Van Ginderachter. Myeloid-Derived Suppressor Cells and Cancer. Springer, 2016.

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Book chapters on the topic ""Inflammation" and "Myeloid derived Suppressor cells""

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Pistoresi-Palencia, María Cristina, María Florencia Harman, and Sofía Daiana Castell. "Myeloid-Derived Suppressor Cells (MDSCs) in Aged Mice: Focus on Inflammation." In Handbook of Immunosenescence. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-99375-1_95.

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Pistoresi-Palencia, María Cristina, María Florencia Harman, and Sofía Daiana Castell. "Myeloid-Derived Suppressor Cells (MDSCs) in Aged Mice: Focus on Inflammation." In Handbook of Immunosenescence. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-64597-1_95-1.

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Fujimura, Taku, and Alexander H. Enk. "Myeloid Derived Suppressor Cells." In Immunology of the Skin. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55855-2_11.

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Nagaraj, Srinivas, and Dmitry I. Gabrilovich. "Myeloid-Derived Suppressor Cells." In Advances in Experimental Medicine and Biology. Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-72005-0_22.

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Shibata, Masahiko, Kenji Gonda, and Seiichi Takenoshita. "MDSC: Myeloid-Derived Suppressor Cells." In Immunotherapy of Cancer. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55031-0_22.

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Alicea-Torres, Kevin, and Dmitry I. Gabrilovich. "Biology of Myeloid-Derived Suppressor Cells." In Oncoimmunology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62431-0_10.

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Badn, Wiaam, and Vincenzo Bronte. "Myeloid-Derived Suppressor Cells in Cancer." In Innate Immune Regulation and Cancer Immunotherapy. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-9914-6_12.

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Kyriakopoulos, Christos E., Alberto J. Montero, and Claudia Marcela Diaz-Montero. "Myeloid-Derived Suppressor Cells in Cancer." In Advances in Tumor Immunology and Immunotherapy. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8809-5_1.

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De Sanctis, Francesco, Vincenzo Bronte, and Stefano Ugel. "Tumor-Induced Myeloid-Derived Suppressor Cells." In Myeloid Cells in Health and Disease. ASM Press, 2017. http://dx.doi.org/10.1128/9781555819194.ch49.

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Rauh, Michael J., Elina K. Cook, and Dawn M. E. Bowdish. "Myeloid-Derived Suppressor Cells in Aged Humans." In Handbook of Immunosenescence. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-99375-1_96.

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Conference papers on the topic ""Inflammation" and "Myeloid derived Suppressor cells""

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Awad, M. S., M. A. Zenkova, and O. V. Markov. "MODULATION OF THE IMMUNOSUPPRESSIVE FUNCTIONS OF EX VIVO GENERATED MURINE MYELOID-DERIVED SUPPRESSOR CELLS WITH CYTOKINES AND TUMOR CONDITIONED MEDIUM." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-208.

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Myeloid-derived suppressor cells (MDSCs) are immune cells linked to immunosuppression in cancer, inflammation, autoimmune diseases, and transplantation. They comprise polymorphonuclear (PMN-MDSCs) and monocytic (M-MDSCs) subsets resembling neutrophils and monocytes. MDSCs suppress other immune cells, primarily T cells.
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Ouzounova, Maria, EunMi Lee, Raziye Piranlioglu, et al. "Abstract 1554: Myeloid derived suppressor cells-mediated inflammation in metastasis and cancer cachexia." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1554.

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Chornoguz, Olesya Y., Lydia Grmail, Pratima Sinha, Konstantin Artemenko, Roman Zubarev, and Suzanne Ostrand-Rosenberg. "Abstract 5316: Inflammation-induced myeloid-derived suppressor cells have enhanced resistance to apoptosis." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-5316.

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Ostrand-Rosenberg, Suzanne, Pratima Sinha, Virginia Clements, Stephanie Bunt, and Minu Srivastava. "Abstract PL03-02: Inflammation-driven myeloid-derived suppressor cells: co-opting anti-tumor immunity to promote tumor progression." In Abstracts: Frontiers in Cancer Prevention Research 2008. American Association for Cancer Research, 2008. http://dx.doi.org/10.1158/1940-6207.prev-08-pl03-02.

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Gonda, Kenji, Masahiko Shibata, Tatsuo Shimura, et al. "Abstract 5416: Myeloid-derived suppressor cells (MDSC) are increased and correlated with immune suppression and chronic inflammation in patients with cancer." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-5416.

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Beury, Daniel W., Katherine H. Parker, and Suzanne Ostrand-Rosenberg. "Abstract 2876: Inflammation of the tumor microenvironment is regulated by myeloid derived suppressor cell and macrophage crosstalk." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2876.

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Berlinger, M., D. N. Hager, and F. R. D'Alessio. "Steroid Induced Modulation of Myeloid Derived Suppressor Cells Results in Increased Suppressor Activity." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3997.

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Schilling, Bastian, Antje Sucker, Klaus Griewank, et al. "Abstract 4714: Vemurafenib reverses immunosuppression by myeloid derived suppressor cells." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-4714.

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Talmadge, James E., Holly Britton, Alicia Dafferner, Phyllis Warkentin, and Kathryn Cole. "Abstract LB-192: Phenotyping human myeloid derived suppressor cells (MDSC) subsets." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-lb-192.

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Fernandez, I. E., F. R. Greiffo, V. Viteri-Alvarez, et al. "Myeloid-Derived Suppressor Cells Orchestrate Immunosuppressive Networks in Idiopathic Pulmonary Fibrosis." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1231.

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Reports on the topic ""Inflammation" and "Myeloid derived Suppressor cells""

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Park, Serk I. Activation of Myeloid-Derived Suppressor Cells in Bone Marrow. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada600504.

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Morales, Johanna K., Maciej Kmieciak, and Masoud H. Manjili. The Role of Myeloid-Derived Suppressor Cells in the Immunotherapy of HER2/neu-Positive Breast Carcinomas. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada515137.

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