Relevant bibliographies by topics / Inflammatory diseases of the maxillofacial region

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'Inflammatory diseases of the maxillofacial region'

Author: Grafiati
Published: 5 June 2025
Last updated: 24 June 2025

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Journal articles on the topic "Inflammatory diseases of the maxillofacial region"

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Normurodov, B. K., J. A. Djuraev, A. Z. Shaumarov, and J. M. Akhmedov. "Frequency and structure of purulent inflammatory diseases of the maxillofacial region." Hirurg (Surgeon), no. 7-8 (July 13, 2020): 73–84. http://dx.doi.org/10.33920/med-15-2004-05.

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The frequency and structure of purulent-inflammatory diseases of maxillofacial region are analyzed. Medical documentation of patients with purulent-inflammatory diseases of maxillofacial region was studied. According to the Department of Oral and Maxillofacial Surgery, multidisciplinary clinic of Tashkent medical academy (TMA) from period 2017–2018yy. specialized medical care for purulent-inflammatory diseases was provided to 593 patients. Some causes of the development of purulent-inflammatory diseases are determined taking into account the spectrum of identified microorganisms. Factors affecting of timing and quality of treatment of purulent inflammatory diseases have been established.
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Eshiev, A., and N. Myrzasheva. "RELATIONSHIP OF THE PREVALENCE OF INFLAMMATORY DISEASES OF THE MAXILLOFACIAL REGION AND CHRONIC NON-INFECTIOUS DISEASES." Scientific heritage, no. 93 (July 22, 2022): 45–47. https://doi.org/10.5281/zenodo.6882425.

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Recently, in maxillofacial surgery and dentistry, it is relevant to study such a problem as the relationship between dental diseases and chronic non-communicable diseases. We conducted a comprehensive clinical and epidemic examination of 1200 patients with inflammatory diseases of the maxillofacial region and neck. Receiving inpatient treatment for maxillofacial surgery at the Osh Interregional United Clinical Hospital from 2019 to 2021 with inflammatory diseases of the maxillofacial region. Concomitant pathologies of iron deficiency anemia were established on the basis of hematological parameters. The aim of the study was to study the prevalence of major dental diseases in people with chronic non-communicable diseases. The result of the study showed that out of 450 patients with an inflammatory disease of the maxillofacial region, there was a chronic non-communicable disease and iron deficiency anemia. The prevalence, concomitant diseases of a non-infectious nature were studied, iron deficiency anemia – 51.6%, diseases of the digestive tract – 17.3%, urinary system – 12.5%, cardiovascular system – 10.2%, chronic lung diseases – 8, four%. The results of the study showed that all patients with iron deficiency anemia according to the severity of the disease were distributed as follows: mild degree – 66.5%, moderate degree – 32.6%, severe degree – 0.9%. Iron deficiency anemia in most cases was found in patients with inflammatory disease in children aged 5 to 14 years old – 38.2%, adults – 13.4%. An adequate assessment of iron deficiency anemia can have a positive effect on the results of treatment of inflammatory diseases of the maxillofacial region and neck. The results of the study allow us to develop evidence-based recommendations on the prevention of major inflammatory diseases of the maxillofacial region and neck.
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Kamalova, Feruza Rahmatilloevna, and Munira Izzatulloevna Tolibova. "IMPROVING THE METHODS OF TREATMENT AND PREVENTION OF COMPLICATIONS OF ODONTOGENIC DISEASES OF THE JAWS IN CHILDREN." Journal of oral medicine and craniofacial research 3, no. 4 (2022): 5. https://doi.org/10.5281/zenodo.7113735.

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Treatment and prevention of inflammatory diseases of the maxillofacial region are one of the main problems of pediatric dentistry. According to a number of researchers, inflammatory diseases of the maxillofacial region account for up to 21% of all surgical and 52% of dental diseases in childhood. In most children, the source of odontogenic inflammatory diseases are complications of caries in temporary teeth. .
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Birmukhanova, A. U., A. T. Tokbergenova, A. S. Almuratova, R. M. Uzhakhova, and Zh B. Baibulova. "Clinical and epidemiological analysis of odontogenic inflammatory diseases of the maxillo-facial area in children." Medicine and ecology, no. 4 (December 26, 2023): 35–39. http://dx.doi.org/10.59598/me-2305-6045-2023-109-4-35-39.

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Children of the Karaganda region have a high prevalence of odontogenic inflammatory diseases of the maxillofacial region. For this purpose, epidemiological material was collected and analyzed from 426 children aged 1 to 17 years inclusive; distribution of medical records of an inpatient was carried out depending on the nosological form of the inflammatory process and covered the period from 2018 to 2022. in the SOE «Multiprofile hospital named after Kh. M. Makazhanov» (Karaganda city), nosological forms: acute purulent periostitis; acute odontogenic osteomyelitis, abscess and phlegmon. In the comparative structure of odontogenic inflammatory diseases of the maxillofacial region, acute odontogenic osteomyelitis of the jaw predominates – 41.8 %, the second place is occupied by odontogenic phlegmon – 36.6 %, followed by acute purulent periostitis – 15 %, odontogenic abscess – 6.6 %.Studies on the level, structure and prevalence of odontogenic inflammatory diseases of the maxillofacial region in children, depending on the place of residence, revealed that in children of urban areas the highest incidence rate was found for acute odontogenic osteomyelitis. Whereas in rural children odontogenic phlegmon and odontogenic abscess occurred on average 2.2 times more often than in urban children, which indicates the severity of the development of odontogenic inflammatory diseases of the maxillofacial region in them.Thus, in our studies, a relationship was found in the prevalence of odontogenic inflammatory diseases of the maxillofacial region between the age characteristics of children and their place of residence.
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Дрегалкина, Анна, Anna Dregalkina, И. Костина, and I. Kostina. "THE STRUCTURE OF DISEASES OF THE MAXILLOFACIAL REGION AMONG RESIDENTS OF SVERDLOVSK REGION." Actual problems in dentistry 14, no. 2 (2018): 68–73. http://dx.doi.org/10.18481/2077-7566-2018-14-2-68-73.

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Object. Improving health infrastructure, improving the quality of medical care provided are fundamental to modern Russia. Currently, there is a high prevalence of dental diseases, which in our country can cause hospitalization or even death of patients. The load of beds of specialized hospitals, the increase in the number of cases of serious complications significantly exacerbate the socio-economic significance of the problem.
 Goal. Describe the structure of diseases of the maxillofacial region among adults and children of the Sverdlovsk region and Yekaterinburg for the period 2013-2017.
 Methodology. A retrospective study of maxillofacial region diseases was conducted in patients who received inpatient treatment in 2013-2017 in medical institutions of Yekaterinburg.
 Results. The analysis of the data showed that inpatient care for patients with maxillofacial pathology is in demand in our region. The most common reason for hospitalization of patients are inflammatory diseases of the maxillo-facial region, especially of odontogenic origin. This situation is observed in both adult and pediatric maxillofacial surgery.Facial trauma in pediatric practice ranked second in frequency of occurrence among the pathologies of the maxillofacial region. In adults, tumors and tumor-like processes make up a significant part of diseases of the maxillofacial region that require inpatient treatment. Despite the progress and improvement of some indicators, today in the structure of maxillofacial surgery of the Sverdlovsk region there are problems, mainly of an organizational nature. There are few specialized departments in the field, the best is to provide assistance in the conditions of independent departments of maxillofacial surgery in close cooperation with related specialists, requires improvement of patient routing, there is no interaction between doctors of various CNC departments and dentists, surgeons, not enough qualified specialists. The solution to these and other questions will allow to raise efficiency of treatment of patients with pathology of the maxillofacial region.
 Conclusions
 1. During the period 2013—2017, there was a steady increase in diseases of the maxillofacial region among the residents of Yekaterinburg and Sverdlovsk region, especially children.
 2. The largest part consists of patients with inflammatory diseases of the maxillofacial region, mainly odontogenic etiology.
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M. Azimov, J. A. Rizaev, and A. M. Azimov. "Clinical and anatomical classification of odontogenic inflammatory diseases of Tashkent state dental institute adapted to ICD-10." Clinical anatomy and operative surgery 19, no. 1 (2020): 61–66. http://dx.doi.org/10.24061/1727-0847.19.1.2020.10.

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Odontogenic inflammatory diseases of the maxillofacial region account for about 25-30 % of all dental diseases. They occupy up to 50 % of the bed fund of specialized clinics. In clinics of pediatric, adult maxillofacial surgery, in Tashkent State Dental Institute (TSDI) annually treats up to 3000 patients with odontogenic inflammatory diseases of the maxillofacial region. In some of them, the disease goes into a chronic form, often the process ends with an unfavorable outcome. All patients were the subject of research. The working classification of odontogenic inflammatory diseases of TSDI adapted to the ICD-10 classification will allow practitioners to clearly state the name of the disease, develop a treatment standard and conduct static processing of the material.
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Steblovskyi, D. V., M. G. Skikevich, and V. V. Bondarenko. "STRUCTURAL FEATURES OF PURULENT INFLAMMATORY DISEASES OF THE MAXILLOFACIAL REGION IN RESIDENTS OF THE POLTAVA REGION." Ukrainian Dental Almanac, no. 4 (December 23, 2020): 50–52. http://dx.doi.org/10.31718/2409-0255.4.2020.09.

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The problem of surgical infections is an urgent problem of medicine today. Despite the improvement of the quality of medical care, improvement of known and discovery of new methods of treatment, the number of patients with this pathology has a clear temporary tendency to increase. Features of the anatomical structure of the maxillofacial area determine the clinical originality of purulent inflammatory diseases, which are characterized by rapidly progressing course and spread with the generalization of the process. As etiological factors for purulent inflammatory diseases of the maxillofacial area can be diseases of the skin of the face and neck, lymph nodes, ENT diseases. The leading role in purulent inflammatory diseases of the maxillofacial area is occupied by odontogenic cause.
 The aim of the study. Investigate the structure and frequency of purulent inflammatory diseases in residents of Poltava region.
 Material and methods. The Department of Maxillofacial Surgery is located on the basis of Poltava Regional Clinical Hospital, provides specialized and high-tech assistance to residents of Poltava region. During the period 2015-2019, a total of 3927 patients were treated, of which purulent inflammatory diseases of the face and neck occurred in 1281 (30.1%): phlegmon - in 582 (44.4%), abscesses - in 699 (55, 5%). Sepsis was complicated by surgical infection in 9 patients (0.9%).
 All patients underwent a clinical examination to clarify complaints, medical history, studied the data of objective examination of the general condition, careful assessment of local status (localization of the process, discoloration, skin temperature, edema, tissue infiltration, checked the amplitude of mouth opening, studied dental formula). All patients underwent a general clinical examination, the results of microbiological monitoring of bacterial cultures were studied. Additional instrumental methods of examination were performed: CT of soft tissues in 35 (3.89%), ultrasound of soft tissues of the neck - in 123 (13.76%), orthopantomography - in 640 (52.38%), radiography of the neck - in 43 (5.1%).
 Among the diseases that form a severe premorbid background, the most significant role is played by HIV and diabetes. Microbiological monitoring has identified as the most common microflora of Staphylococcus aureus, Streptococcus constellatus and Streptococcus mitis. Adequately performed surgery in combination with active complex therapy in the postoperative period, including in addition to traditional therapy “Biocerulin”, allows to reduce the duration of inpatient treatment to 7.3 + 0.3 (in the control group when using traditional dressings - 11 , 5 + 0,5) and ensures the absence of fatalities.
 Conclusions. Purulent inflammatory diseases of the maxillofacial area are an urgent problem of surgery, accounting for 9.8% of those hospitalized in the department of maxillofacial surgery.
 A significant predominance of the most able-bodied age group (41.0%) puts the problem of the disease in the category of socially significant.
 The leading role of odontogenic causes of purulent inflammatory diseases indicates the lateness of patients in dental clinics, the neglect of oral hygiene and the timeliness of remedial measures.
 Early surgery in combination with antibacterial therapy in accordance with microbiological monitoring and the use of “Biocerulin”, allows to achieve satisfactory immediate results of treatment.
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Kurbonov, Yokubjon Khamdamovich, Shukhrat Abdujalilovich Boymuradov, and Jamolbek Abdukakharovich Djuraev. "Overview Of Comprehensive Treatment Of Acute Purulent-Inflammatory Diseases Of The Face And Neck." American Journal of Medical Sciences and Pharmaceutical Research 03, no. 01 (2021): 15–23. http://dx.doi.org/10.37547/tajmspr/volume03issue01-04.

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The aim of the work is to systematize the data of special literature for the clearest definition of the directions of studying the modern approach to the diagnosis, prognosis and treatment of pyoinflammatory processes in the maxillofacial region and neck. As a result of the analysis of the data of special literature, it becomes obvious that in recent decades the idea of the etiology and pathogenesis of pyoinflammatory processes in the maxillofacial region and neck has changed, which determines the need for further search for new informative methods of diagnosis, prognosis, as well as the most effective methods of treatment and prevention of complications for this pathology.
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Grachev, denis, Said Ksembaev, Elima Agatieva, and Larisa Mubarakova. "PREVALENCE AND CHARACTERISTICS OF ACUTE PURULENT-INFLAMMATORY DISEASES OF THE MAXILLOFACIAL REGION." Actual problems in dentistry 20, no. 4 (2025): 40–45. https://doi.org/10.18481/2077-7566-2024-20-4-40-45.

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Subject. A review of the literature devoted to the urgent problem of dentistry – acute purulent-inflammatory diseases of the maxillofacial region is presented. Purulent inflammatory diseases in the jaw and face area constitute an important group of diseases with high medical and social significance, since most patients are of working age and often require hospitalization. Early diagnosis and treatment play a key role in preventing serious life-threatening complications. The purpose of the study is to study the materials of publications devoted to the ethology, pathogenesis and prevalence of acute purulent–inflammatory diseases of the maxillofacial region. Methodology. In detail, in the light of modern concepts, modern methods of treating patients with acute purulent-inflammatory diseases of the maxillofacial region are described. Results. Thus, a recent retrospective analysis conducted as part of the study of the prevalence of odontogenic phlegmon among hospitalized patients demonstrated that the level of patients with inflammatory diseases in the field of maxillofacial surgery remains stable. This indicates that the problem of odontogenic infections does not lose its relevance and requires constant attention from the medical community. Other studies also confirm this trend, pointing to the immutability of indicators of purulent-inflammatory diseases in this area. For example, in some clinics there is an increase in the number of cases associated with complications after dental procedures, which may be due to insufficient prevention and control of infections. It is important to note that odontogenic phlegmons can occur not only as a result of neglected dental diseases, but also as a result of poor-quality medical manipulations. Conclusions. The results of the review indicate that the stable level of odontogenic phlegmon among hospitalized patients indicates the need for further study and development of effective strategies to reduce morbidity in this area.
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Orif, Shokirovich Musinov, and Ruzimurodova Shukhratovna. "PECULIARITIES OF THE EFFECT OF TRAUMEL C ON THE CLINICAL COURSE OF PURULENT INFLAMMATORY DISEASES OF THE MAXILLOFACIAL REGION." EURASIAN JOURNAL OF ACADEMIC RESEARCH 1, no. 1 (2021): 206–9. https://doi.org/10.5281/zenodo.4711313.

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<em>The number of patients with purulent inflammatory diseases of the maxillofacial region is increasing. During the last decade the growth of scientific interest to the problem under study has been marked. Inflammatory maxillofacial region diseases one of the main observed signs of heavy course of the disease complication of which can be acute odontogenic mediastinitis, meningitis, sepsis, sinus thrombosis of dura mater. As a consequence, the number of lethal outcomes increases, which, according to various authors, can range from 25% to 55% especially when the inflammatory process is generalized, leading to septic shock, where the probability of a lethal outcome increases to 80%.</em>
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Dissertations / Theses on the topic "Inflammatory diseases of the maxillofacial region"

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Палій, Т. А. "Лімфотропне введення антибіотиків при запальних захворюваннях ЩЛД". Thesis, Буковинський державний медичний університет, 2017. http://essuir.sumdu.edu.ua/handle/123456789/51758.

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Проведено аналізу сучасних даних літератури щодо лімфотропного введення антибіотиків при запальних захворюваннях щелепно-лицевої ділянки. Доведено, що ефективність лімфотропного введення антибіотиків переважає традиційні методи за рахунок впливу не тільки на місце гнійного запалення, а й на організм в цілому.<br>Проведен анализ современных данных литературы по лимфотропному введению антибиотиков при воспалительных заболеваниях челюстно-лицевой области. Доказано, что эффективность лимфотропного введения антибиотиков имеет преимущества перед традиционными методами за счет влияния не только на месте гнойного воспаления, но и на организм в целом.
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Books on the topic "Inflammatory diseases of the maxillofacial region"

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Dregalkina, Anna, Irina Kostina, Margarita Shimova, and Olga Schneider. INFLAMMATORY DISEASES OF MAXILLOFACIAL AREA. CURRENT FEATURES OF CLINICAL COURSE, PRINCIPLES OF DIAGNOSIS AND TREATMENT. TIRAZH Publishing House, 2020. http://dx.doi.org/10.18481/978-5-89895-940-1.

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The manual was prepared for dentists, surgeons and maxillofacial surgeons during additional professional training in the advanced training program "Selected Issues of Surgical Dentistry and Maxillofacial Surgery" in a remote form. The manual provides up-to-date information on the prevalence, features of the clinical course, diagnosis, principles of treatment of odontogenic inflammatory diseases that are most often encountered in the practice of a dentist surgeon and maxillofacial surgeon. The manual is illustrated, contains tasks in a test form, situational tasks for self-testing by students of the material studied.&#x0D; The manual is recommended for systematizing and deepening professional knowledge in the diagnosis and treatment of odontogenic inflammatory processes.
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Wackenheim, A., and Yves Dirheimer. Craniovertebral Region in Chronic Inflammatory Rheumatic Diseases. Springer London, Limited, 2011.

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Wackenheim, A., and Yves Dirheimer. Craniovertebral Region in Chronic Inflammatory Rheumatic Diseases. Springer London, Limited, 2012.

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Parkes, Joanna E., Simon Rothwell, and Janine A. Lamb. Aetiology and pathogenesis. Edited by Hector Chinoy and Robert Cooper. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198754121.003.0003.

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The aetiology and pathogenesis of idiopathic inflammatory myopathies (IIM) is poorly understood; IIM are thought to result from exposure to environmental factors in genetically susceptible individuals. Both innate and adaptive immune responses are involved in IIM, and there is increasing evidence that non-inflammatory mechanisms play an important role in disease pathology. Several environmental risk factors, including infectious agents, ultraviolet radiation, cigarette smoking, and exposure to statins, have been implicated. Genetic studies have identified the major histocompatibility complex as the most strongly associated region, while recent large scale genome-wide studies have implicated genes that commonly regulate the adaptive immune response, which overlap with other seropositive autoimmune diseases. Integrating data across these various fields should facilitate refined models of disease pathogenesis.
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Hughes, Jeremy. Proteinuria as a direct cause of progression. Edited by David J. Goldsmith. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0137.

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Proximal tubular cells reabsorb any filtered proteins during health via cell surface receptors such as megalin and cubulin so that very low levels of protein are present in the excreted urine. Significant proteinuria is a common finding in patients with many renal diseases. Proteinuria is a marker of glomerular damage and podocyte loss and injury in particular. The degree of proteinuria at presentation or during the course of the disease correlates with long-term outcome in many renal diseases. Proteinuria per se may be nephrotoxic and thus directly relevant to the progression of renal disease rather than simply acting as a marker of the severity of glomerular injury and podocytes loss. Seminal studies used the atypical renal anatomy of the axolotl to instill proteins directly into the tubular lumen without requiring passage through the glomerulus. This indicated that tubular protein could be cytotoxic and induce interstitial inflammation and fibrosis in the peritubular region. Cell culture studies demonstrate that exposure to proteins results in proximal tubular cell activation and the production of pro-inflammatory and pro-fibrotic mediators. Proximal tubular cell death occurred in some studies reinforcing the potential of protein to exert cytotoxic effects via oxidative stress or endoplasmic reticulum stress. Analysis of renal biopsy material from both experimental studies using models of proteinuric disease or patients with various proteinuric diseases provided evidence of activation of transcription factors and production of chemokines and pro-inflammatory mediators by proximal tubular cells. These data strongly suggest that although proteinuria is the result of glomerular disease it also represents an important cause of progression in patients with chronic kidney disease associated with proteinuria.
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Book chapters on the topic "Inflammatory diseases of the maxillofacial region"

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Yao, Li, and Heng Liu. "Imaging Anatomy of Maxillofacial Region." In Radiology of Infectious and Inflammatory Diseases - Volume 2. Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-8841-6_10.

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Pompili, Giovanni Guido, Alice Munari, Paolo Rigamonti, and Gian Paolo Cornalba. "MRI Anatomy of the Anorectal Region." In Imaging of Perianal Inflammatory Diseases. Springer Milan, 2013. http://dx.doi.org/10.1007/978-88-470-2847-0_2.

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Maconi, Giovanni, Elisa Radice, and Giulio A. Santoro. "Ultrasound Anatomy of the Anorectal Region." In Imaging of Perianal Inflammatory Diseases. Springer Milan, 2013. http://dx.doi.org/10.1007/978-88-470-2847-0_3.

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Liu, Heng, Mengmeng Yu, Xuedong Bai, et al. "Lesions of Maxillofacial Mouth Floor." In Radiology of Infectious and Inflammatory Diseases - Volume 2. Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-8841-6_26.

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Stein, Ernst. "Inflammatory Diseases of the Colon, Rectum, Anus and Perianal Region." In Anorectal and Colon Diseases. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-18977-7_17.

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"Specific Inflammatory Diseases of the Oral Cavity and Maxillofacial Region: a textbook." In Specific Inflammatory Diseases of the Oral Cavity and Maxillofacial Region: a textbook, edited by A. M. Panin. OOO «GEOTAR-Media» Publishing Group, 2022. http://dx.doi.org/10.33029/9704-7255-2-sid-2023-1-144.

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Karjodkar, Freny. "Infections and Inflammatory Lesions and Systemic Diseases Affecting the Jaws." In Essentials of Oral and Maxillofacial Radiology. Jaypee Brothers Medical Publishers (P) Ltd., 2014. http://dx.doi.org/10.5005/jp/books/12300_20.

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Neville, Brad W., Douglas D. Damm, Carl M. Allen, and Angela C. Chi. "Developmental Defects of the Oral and Maxillofacial Region." In Color Atlas of Oral and Maxillofacial Diseases. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-323-55225-7.00001-4.

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Tarı Selçuk, Kevser. "Epidemiology of Inflammation-Related Diseases." In Role of Nutrition in Providing Pro-/Anti-Inflammatory Balance. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-3594-3.ch002.

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Inflammation, a vital defense mechanism for health, is defined as the immune system's response to harmful stimuli such as pathogens, damaged cells, toxic compounds or irradiation. Inflammation is usually examined in two groups: acute and chronic. Chronic inflammation instigates various kinds of diseases that cause premature mortality and morbidity such us cardiovascular diseases, cancer, diabetes mellitus (DM), asthma-chronic obstructive pulmonary disease (COPD), obesity, metabolic syndrome (METs), inflammatory bowel disease (IBD), rheumatoid arthritis (RA), multiple sclerosis (MS), osteoporosis, and neurological diseases via dysregulation of various signaling pathways such as nuclear factor kappa-B (NF-κB), signal transducer, activator of transcription 3 (STAT3), etc. These inflammation-related diseases are among the major causes of mortality and morbidity in almost every region of the world. Studies have shown that these diseases associated with inflammation have tended to increase worldwide.
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Croker, Jennifer A., and Robert P. Kimberly. "Immunoglobulin Fc and Related Receptor Genes." In Genetic Susceptibility to Infectious Diseases. Oxford University PressNew York, NY, 2008. http://dx.doi.org/10.1093/oso/9780195174908.003.0009.

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Abstract Immunoglobulin Fc receptors (FcRs), members of the immunoglobulin gene superfamily, are membranebound glycoproteins that function in the immune system by coupling antibodies to effector functions in a cell. The different FcRs, while each interacting with the constant (Fc) region of an antibody (Ab), may bind to ligand with different affinities. Each FcR utilizes partiallyoverlapping, aswellasdiscrete, signalingmechanisms to elicit cellular immune responses, including phagocytosis, degranulation, endocytosis, immunecomplex clearance, Ab-dependent cell cytotoxicity, and transcriptional regulation of cytokine and chemokine expression (Daeron, 1997). Clinically, genetic variants found in several of the FcRs have been implicated in several inflammatory, rheumatic, and autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and vasculitis (Croker and Kimberly, 2005). Recent data also implicate FcR function in susceptibility to infection, particularly inpatients with inflammatory or autoimmune diseases (Kimberly et al., 1988, 1998; Hughes et al., 2004).
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Conference papers on the topic "Inflammatory diseases of the maxillofacial region"

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Землин, Иван Александрович, Марина Николаевна Митропанова, Владимир Викторович Волобуев, Елена Олеговна Любомирская, and Спартак Шаликоевич Антониадис. "KEY PERFORMANCE INDICATORS OF THE DEPARTMENT OF ORAL AND MAXILLOFACIAL SURGERY OF THE MINISTRY OF HEALTH OF THE KRASNODAR REGION IN 2017-2019." In Психология. Спорт. Здравоохранение: сборник избранных статей по материалам Международной научной конференции (Санкт-Петербург, Июнь 2020). Crossref, 2020. http://dx.doi.org/10.37539/psm291.2020.39.69.009.

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Анализ трехлетней деятельности отделения челюстно-лицевой хирургии выявил положительную динамику основных показателей работы подразделения. В структуре патологии челюстно-лицевой области преобладают опухоли (39,4%), воспалительные заболевания (33,0%), врожденные пороки развития (11,3%), травмы (11,0%). The analysis of the three-year activity of the Department of maxillofacial surgery revealed a positive dynamics of the main indicators of the division. The structure of maxillofacial pathology is dominated by tumors (39.4%), inflammatory diseases (33.0%), congenital malformations (11.3%) and injuries (11.0%).
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Maksudov, Dilshod, Aziza Azimova, and Shokhsanam Mamadyarova. "CLINICAL COURSE OF INFLAMMATORY DISEASES OF THE MAXILLOFACIAL REGION IN PATIENTS WITH VIRAL HEPATITIS B." In ADVANCED DISCOVERIES OF MODERN SCIENCE: EXPERIENCE, APPROACHES AND INNOVATIONS. European Scientific Platform, 2021. http://dx.doi.org/10.36074/logos-09.04.2021.v2.20.

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Kokorina, N. V., A. A. Ershova-Pavlova, and V. A. Kazyuchits. "CONGENITAL MALFORMATIONS OF THE MAXILLOFACIAL REGION IN URBANIZED TERRITORIES OF BELARUS." In SAKHAROV READINGS 2022: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2022. http://dx.doi.org/10.46646/sakh-2022-1-81-84.

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Congenital malformations (CM) are one of the most urgent medical and social problems due to their high frequency and severity. Congenital deformities of the maxillofacial region occupy the second place among all human malformations. According to WHO, the prevalence of congenital malformations of the maxillofacial region in the world is on average 1 per 600 newborns. Recently, there has been a tendency for a steady increase in the frequency of their occurrence, and in recent years, among these defects, the proportion of cleft palate, that is, a more severe pathology, has increased [1]. Severe congenital malformations of the maxillofacial region in children are often not only a medical but also a social problem, which requires a set of measures aimed at the prevention of these diseases, as well as the treatment and rehabilitation of patients with this pathology.
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Kharitonov, Iu M., M. A. Gubin, and R. N. Kikov. "The problem of repeated operations in patients with complications of purulent inflammatory diseases of the maxillofacial area and neck." In ТЕНДЕНЦИИ РАЗВИТИЯ НАУКИ И ОБРАЗОВАНИЯ. НИЦ «Л-Журнал», 2019. http://dx.doi.org/10.18411/lj-01-2019-106.

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Zhuang, Xiaoying, and Huang-Ge Zhang. "Abstract 4831: Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-4831.

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Rolindo, Saullo José Silva, Isabela Louise Caldeira Silva, Samuel Campos Silva, and Denise Sisterolli Diniz. "Vasculitis of the central nervous system secondary to amiopathic dermatomyositis: A case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.661.

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Context: Dermatomyositis (DM) is an idiopathic inflammatory myopathy, characterized by proximal skeletal muscle weakness, associated with a variety of characteristic skin manifestations. A form called Amiopathic Dermatomyositis (AD) is a condition that patients have cutaneous findings characteristic of DM without weakness and/or normal muscle enzymes. In turn, central nervous system (CNS) vasculitis refers to a wide spectrum of diseases that result in inflammation and destruction of the blood vessels of the brain, spinal cord and meninges. Case report: Female, 54 years old, reports for 3 months a progressive myalgia, paraparesis and edema in the proximal region of the lower limbs, evolving in the last weeks with erythematous and itchy lesions on the trunk (in shawl), feet and hands, with subsequent peeling of these (mechanic’s hands). During diagnostic investigation she presented epileptic seizures with behavioral arrest, right hemiparesis and motor aphasia. It evolved with a new stroke in the left frontoparietal region. Bilateral angiography showed points of constriction of segments of the middle cerebral artery bilaterally, compatible with CNS vasculitis. Therefore, with the exclusion of other secondary causes of arteritis, associated with the marker of positive inflammatory myopathy (Anti-Jo1) and CPK within the serum levels of normality, the diagnosis of the stroke secondary to AD was closed. Conclusions: Both CNS vasculitis and AD are rare conditions, characteristically diagnoses of exclusion, deserving to be remembered in clinical cases with singular manifestations, as reported in this case.
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Chumachkova, Е. A., S. A. Portenko, E. S. Kazakova, et al. "EPIDEMIOLOGICAL FEATURES OF THE COURSE OF COMMUNITY-ACQUIRED PNEUMONIA IN PATIENTS OF THE CITY OF SARATOV AND SARATOV OBLAST." In Molecular Diagnostics and Biosafety. Federal Budget Institute of Science 'Central Research Institute for Epidemiology', 2020. http://dx.doi.org/10.36233/978-5-9900432-9-9-186.

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The aim of the study was to identify the epidemiological features of the course of community-acquired pneumonia among patients in the city of Saratov and the Saratov region during the epidemic of a new coronavirus infection. The medical records of 129 patients of various ages with a confirmed diagnosis of community-acquired pneumonia, who were on inpatient and outpatient treatment, were analyzed. The study established the predominance of pneumonia caused by COVID-19, compared to pneumonia caused by other etiological agents, and the pattern of identification of mild, moderate and severe forms of the disease from the moment the first signs of the disease appear. The computed tomography of the chest organs was proved to be the most informative diagnostic method. The severity of the inflammatory process in the lungs was analyzed depending on the age of the patient, gender, and the presence of concomitant chronic diseases.
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Bernardes, Leonardo de Sousa, Marina Trombin Marques, Matheus Gonçalves Maia, et al. "Acute Vogt-Koyanagi-Harada: a case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.037.

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Context: Vogt-Koyanagi-Harada disease is an inflammatory disorder, which presents with intraocular, auditory and central nervous system involvement. It has two distinct courses: acute onset and chronic recurrence, whose differential diagnoses are, respectively, diseases of the optic neuromyelitis spectrum, and chronic meningitis. The diagnostic criteria developed by the international disease committee in 2001 classify patients into: probable disease (ocular findings only), incomplete (ocular plus cutaneous system or neurological manifestations) and complete (when the three forms occur together). Methods: Report the case of a patient seen at the emergency room of Santa Casa de São Paulo, diagnosed with Vogt-Koyanagi-Harada disease. Case report: 43-year-old woman, reporting occipital headache, with irradiation to the retro-orbital region, progressed to sudden bilateral amaurosis, in addition to conjunctival hyperemia. Neurological physical examination presented bilateral visual acuity (Snellen)&gt; 20/200, poorly delimited optical discs. Uveitis and scleritis were also found. Brain and orbit MRI showed: bilateral retinal detachment, with small subretinal collections; regular thickening and impregnation of the choroid; tenuous episcleral impregnation; alteration of the sign of the inner ears, more evident in the cochleae; tenuous linear leptomeningeal impregnation at the level of the cerebellobulbar cistern. Liquor: 21 cells (99% lymphocytes), 31 proteins and 47 glucose, negative culture for bacteria. We proceeded to infusion 1000mg of methylprednisolone for 3 days, with daily use, subsequently, of prednisone 60mg, with significant improvement of the condition. Conclusions: It is a rare disease, but it must be recognized by every neurologist, since it is treatable and can leave serious visual sequelae.
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Mendes, Larissa Braga, Gabriel Pinheiro Martins de Almeida e. Souza, Marianna Pinheiro Moraes de Moraes, José Luiz Pedroso, and Orlando Graziani Povoas Barsottini. "Hypertrophic pachymeningitis associated with systemic lupus erythematosus: a case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.764.

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Introduction: Hypertrophic pachymeningitis is a chronic inflammatory process that results in focal or diffuse thickening of the dura mater. Nowadays, it’s an uncommon cause of neurological symptoms and has been mainly associated with infections, inflammatory diseases and carcinomatosis. This is a report of a single case based on retrospective analysis of the patient’s medical records. Case report: A 48-year-old woman was admitted in the emergency department with a two-month history of severe headaches that worsened with neck flexion and four episodes of focal to bilateral tonic-clonic seizures. In addition to that, she also complained of intermittent gritty sensation and redness in both eyes and arthritis of the hand and wrist joints. Her past medical history included systemic lupus erythematosus, bilateral lower limb deep venous thrombosis and cerebral venous thrombosis (CVT). She was on anticoagulant therapy with rivaroxaban 20 mg daily at the time. On admission, patient presented with bilateral conjunctival hyperemia and slit-lamp examination showed mild anterior chamber flare reaction (grade of 2+). Neurologic examination revealed impaired attention and nuchal rigidity. Brain magnetic resonance imaging was performed and showed linear dural thickening and diffuse pachymeningeal post-contrast enhancement over cerebral convexities, falx cerebri and cerebellar tentorium, with hyperintense signal on T2- weighted sequence in the subcortical region of the right frontal lobes, which might have resulted from obstruction of venous reflux caused by previous CVT. Brain venogram demonstrated partial recanalization of superior sagittal sinus. Lumbar puncture revealed a clear cerebrospinal fluid (CSF) with 12 cells/ mm3 (82% lymphocytes, 13% monocytes, 5% plasmocytes), total protein of 46 mg/dL and glucose of 58 mg/dL. Search for infectious agents by microscopy, culture and molecular testing resulted negative. Systemic investigation was negative for infections or metabolic dysfunction, but it revealed elevated inflammatory markers and hypocomplementemia. Her panel of autoantibodies revealed an ANA titer of 1:640 with a nuclear homogeneous pattern and was negative for the others (anti-dsDNA, anti-Sm, anti-RO, anti-LA, anti-RNP, RF). The patient was then treated with intravenous methylprednisolone 1 g daily for five days and followed by maintenance treatment with oral prednisone 60 mg daily. She showed good improvement of symptoms, as well as a significant reduction of CSF leucocytes and protein content. Unfortunately, it was not possible to obtain a meningeal biopsy at the time. The patient was finally discharged from the hospital and, given the rare association between pachymeningitis and SLE, is expected to return for a follow-up consultation with neurology for additional investigation. Conclusion: Although hypertrophic pachymeningitis has been related with some autoimmune disorders, it is an extremely rare form of nervous system manifestation in SLE. Despite the plausible relationship between the patient’s SLE disease activity and hypertrophic pachymeningitis, further investigation is still required to rule out other etiologies. Nevertheless, we hope our report will raise awareness of hypertrophic pachymeningitis as a possible differential diagnosis in SLE patients with new-onset headache with nuchal rigidity.
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Graça, Santhiago Calvelo, Tainá Mosca, Wilma Carvalho Neves Forte, Vivian Dias Baptista Gagliardi, and Rubens Jose Gagliardi. "Association of neutrophil/ lymphocyte ratio with risk factors and severity in ischemic stroke." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.438.

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Stroke is the second leading cause of death and the primary cause of disability in Brazil. Ischemia resulting from a stroke triggers an inflammatory response in the central nervous system, primarily mediated by neutrophils, lymphocytes, and macrophages. Recent research suggests that the neutrophil/lymphocyte ratio (NLR) in peripheral blood can serve as a reliable marker of systemic inflammation in various diseases. The present study aims to quantify the NLR in patients diagnosed with ischemic stroke, who received treatment at a specialized clinic of a university hospital situated in the central region of São Paulo. Additionally, the study aims to investigate if any correlation exists between NLR values and risk factors associated with ischemic stroke and its severity — assessed using the National Institutes of Health Stroke Scale (NIHSS). This retrospective study is based on medical records of patients aged over 18 years, who had ischemic stroke between 2017 and 2022. The collection of clinical data includes information on the type of ischemic stroke and the presence of risk factors. The quantification of NLR is performed by analyzing blood count data from the patients’ medical records. Of the 194 stroke patients whose data were collected, 80.5% had NLR values exceeding 2, a value considered non-physiological by literature and preliminary data obtained from healthy individuals at the same university hospital. It was also observed that patients with a more severe condition, according to the NIHSS scale, had a higher NLR. However, no statistically significant correlation was found between NLR, types of stroke, and the presence of risk factors. In conclusion, stroke patients exhibit a higher neutrophil-lymphocyte ratio, which is associated with the severity of the condition but not with risk factors. NLR can be a prognostic marker of stroke.
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Reports on the topic "Inflammatory diseases of the maxillofacial region"

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Liu, Miao, Hongan Wang, Jing Lu, et al. Vitamin D supplementation in the treatment of Myasthenia Gravis A protocol for a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.9.0129.

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Review question / Objective: The patients should meet the internationally recognized diagnostic criteria for myasthenia gravis and be definitely diagnosed as myasthenia gravis, excluding MG patients caused by congenital, drug and other factors, as well as patients with serious primary diseases, autoimmune diseases or mental diseases. Patients are not restricted by race, region, gender, age, background, course of disease and other factors. We will focus on trials using vitamin D as an intervention at any dose and in any regimen (eg daily/weekly/monthly intake). The control group was routinely given western medicine, including cholinesterase inhibitors, glucocorticoids, immunosuppressants, alone or in combination, or placebo. The intervention group was treated with vitamin D on the basis of western medicine treatment in the control group. The specific dosage form and dose were not limited, and the shortest course of treatment should be 4 weeks. Main outcome measures: (1) Quantitative score of myasthenia gravis (QMG); (2) Recurrence rate; (3) Effective. Secondary outcome measures: (1) The level of serum acetylcholine receptor antibody (AchRab); (2) The levels of inflammatory factors such as IL-6 and IL-10; (3) Clinical absolute score; (4) TCM syndrome score scale; (5) Quality of life score (QOL); (6) Incidence rate of adverse events. All randomized controlled trials (RCT) literatures from the establishment to September 2022 were retrieved and classified.
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Elmann, Anat, Orly Lazarov, Joel Kashman, and Rivka Ofir. therapeutic potential of a desert plant and its active compounds for Alzheimer's Disease. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7597913.bard.

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We chose to focus our investigations on the effect of the active forms, TTF and AcA, rather than the whole (crude) extract. 1. To establish cultivation program designed to develop lead cultivar/s (which will be selected from the different Af accessions) with the highest yield of the active compounds TTF and/or achillolide A (AcA). These cultivar/s will be the source for the purification of large amounts of the active compounds when needed in the future for functional foods/drug development. This task was completed. 2. To determine the effect of the Af extract, TTF and AcA on neuronal vulnerability to oxidative stress in cultured neurons expressing FAD-linked mutants.Compounds were tested in N2a neuroblastoma cell line. In addition, we have tested the effects of TTF and AcA on signaling events promoted by H₂O₂ in astrocytes and by β-amyloid in neuronal N2a cells. 3. To determine the effect of the Af extract, TTF and AcA on neuropathology (amyloidosis and tau phosphorylation) in cultured neurons expressing FAD-linked mutants. 4. To determine the effect of A¦ extract, AcA and TTF on FAD-linked neuropathology (amyloidosis, tau phosphorylation and inflammation) in transgenic mice. 5. To examine whether A¦ extract, TTF and AcA can reverse behavioral deficits in APPswe/PS1DE9 mice, and affect learning and memory and cognitive performance in these FAD-linked transgenic mice. Background to the topic.Neuroinflammation, oxidative stress, glutamate toxicity and amyloid beta (Ab) toxicity are involved in the pathogenesis of Alzheimer's diseases. We have previously purified from Achilleafragrantissimatwo active compounds: a protective flavonoid named 3,5,4’-trihydroxy-6,7,3’-trimethoxyflavone (TTF, Fl-72/2) and an anti-inflammatory sesquiterpenelactone named achillolide A (AcA). Major conclusions, solutions, achievements. In this study we could show that TTF and AcA protected cultured astrocytes from H₂O₂ –induced cell death via interference with cell signaling events. TTF inhibited SAPK/JNK, ERK1/2, MEK1 and CREBphosphorylation, while AcA inhibited only ERK1/2 and MEK1 phosphorylation. In addition to its protective activities, TTF had also anti-inflammatory activities, and inhibited the LPS-elicited secretion of the proinflammatorycytokinesInterleukin 6 (IL-6) and IL-1b from cultured microglial cells. Moreover, TTF and AcA protected neuronal cells from glutamate and Abcytotoxicity by reducing the glutamate and amyloid beta induced levels of intracellular reactive oxygen species (ROS) and via interference with cell signaling events induced by Ab. These compounds also reduced amyloid precursor protein net processing in vitro and in vivo in a mouse model for Alzheimer’s disease and improvedperformance in the novel object recognition learning and memory task. Conclusion: TTF and AcA are potential candidates to be developed as drugs or food additives to prevent, postpone or ameliorate Alzheimer’s disease. Implications, both scientific and agricultural.The synthesis ofAcA and TTF is very complicated. Thus, the plant itself will be the source for the isolation of these compounds or their precursors for synthesis. Therefore, Achilleafragrantissima could be developed into a new crop with industrial potential for the Arava-Negev area in Israel, and will generate more working places in this region.
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