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Journal articles on the topic 'Inflammatory Fibroid Polyp'

Author: Grafiati

Published: 7 June 2025

Last updated: 16 July 2025

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1

Ng, C., KY Lam, TS Gupta, and YH Ho. "Inflammatory Fibroid Polyp of the Caecum in a Patient with Neurofibromatosis." Annals of the Academy of Medicine, Singapore 33, no. 6 (2004): 797–99. http://dx.doi.org/10.47102/annals-acadmedsg.ngc.

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Introduction: Inflammatory fibroid polyp of the large intestine is uncommon. To our knowledge, this condition has not been reported in a patient with neurofibromatosis. Clinical Picture: In this report, a 66-year-old woman with neurofibromatosis was found to have a large polyp in the caecum. Treatment: Right hemicolectomy was performed because of the size of the polyp. Outcome: Pathological examination showed that the polyp was an inflammatory fibroid polyp. Conclusion: Clinicians should be aware that inflammatory fibroid polyps could be one of the many manifestations of neurofibromatosis in the gastrointestinal tract.

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Rais, Meryem, Hafsa Chahdi, Mohammed Elfahssi, Abderrahmane Albouzidi, and Mohamed Oukabli. "An Unusual Cause of Intestinal Obstruction in a Young Adult Patient: Inflammatory Fibroid Polyp." Case Reports in Surgery 2017 (2017): 1–4. http://dx.doi.org/10.1155/2017/3675848.

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Inflammatory fibroid polyps are uncommon benign lesions that originate in the submucosa of the gastrointestinal tract. The stomach and the ileum are the most commonly affected sites. Although inflammatory fibroid polyp is one of the rare conditions leading to intestinal obstruction in adults, it should be considered as a possible diagnosis in obstructive tumors of the small bowel causing intussusceptions. We present one case of inflammatory fibroid polyp as a rare cause of intussusception in a young adult patient.

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Karuhanga, Theresia, Caroline Ngimba, and James J. Yahaya. "Inflammatory Fibroid Polyp in a 48-Year-Old Male: A Rare Cause of Intussusception." Case Reports in Surgery 2020 (January 7, 2020): 1–5. http://dx.doi.org/10.1155/2020/9251042.

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Inflammatory fibroid polyp is a neoplastic condition affecting the gastrointestinal tract and particularly the gastric antrum. It is virtually a benign submucosal mass comprising mesenchymal cells and numerous small blood vessels with inflammatory cells and commonly eosinophils. Patients with inflammatory fibroid polyps usually present clinically with mechanical intestinal obstruction with or without intussusception. Herein, we present a case of a 48-year-old male with a known history of schizophrenia who presented with mechanical intestinal obstruction following intussusception due to inflammatory fibroid polyp involving the proximal jejunojejunal part of the jejunum.

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Hunt, HeikeV, Kimberly Woodward, and LisaM Gangarosa. "Gastric inflammatory fibroid polyp." Indian Journal of Pathology and Microbiology 54, no. 3 (2011): 622. http://dx.doi.org/10.4103/0377-4929.85120.

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Aydin, Ahmet, Fatih Tekin, Fulya Gunsar, and Muge Tuncyurek. "Gastric inflammatory fibroid polyp." Gastrointestinal Endoscopy 60, no. 5 (2004): 802–3. http://dx.doi.org/10.1016/s0016-5107(04)02027-9.

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6

Bosch, O., C. González Campos, A. Jurado, et al. "Esophageal inflammatory fibroid polyp." Digestive Diseases and Sciences 39, no. 12 (1994): 2561–66. http://dx.doi.org/10.1007/bf02087691.

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7

Kafle, Santosh Upadhyay, P. Upadhyaya, S. Karki, S. Adhikary, and R. Agarwal. "Inflammatory fibroid polyp in ileum causing adult intussusceptions." Health Renaissance 11, no. 2 (2013): 166–68. http://dx.doi.org/10.3126/hren.v11i2.8227.

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Inflammatory fibroid polyps are believed to occur in response to local noxious stimuli. They are uncommon benign but well documented solitary polypoid lesions occurring in gastrointestinal tract; most commonly in stomach. A rare entities of two adult intussusceptions due to inflammatory fibroid polyp in ileum has been reported in this article. Health Renaissance, January-April 2013; Vol. 11 No.1; 166-168 DOI: http://dx.doi.org/10.3126/hren.v11i2.8227

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8

Kalaskar, Nitin, Sharad M. Tanga, Ravindra B. Dhaded, and Puneeth Thalasta. "A rare case of adult Ileo-ileal intussusception due to inflammatory fibroid polyp." International Surgery Journal 4, no. 2 (2017): 813. http://dx.doi.org/10.18203/2349-2902.isj20170240.

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Inflammatory fibroid polyps are uncommon; moreover, that polyp causing secondary intussusception in an adult are still rarer. Here, we report a case of inflammatory fibroid polyp of the small bowel that presented as just vague pain in the abdomen in a 48-year-old woman. Even though investigations reported Ileo-ileal intussusception caused by a polyp, the patient did not have clinical symptoms that could be correlated. The rareness of the disease made it a clinical challenge to subject the patient to laparotomy. The rareness of non-neoplastic condition being the cause for adult ileo-ileal intussusception and the clinical challenge associated with it makes it a case worth reporting.

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9

Lee, Eun Sun. "Inflammatory Fibroid Polyp of Ileum with Intussusception." Korean Journal of Abdominal Radiology 6, no. 1 (2022): 72–76. http://dx.doi.org/10.52668/kjar.2022.00108.

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Inflammatory fibroid polyps are rare benign tumors of the gastrointestinal tract with the gastric antrum being the most common site, followed by the ileum. This case report presents a large inflammatory polyp causing ileal intussusception in a 78-year-old male patient, complaining abdominal pain, with a literature review.

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10

International, Journal of Medical Science and Innovative Research (IJMSIR). "Inflammatory Fibroid Polyp of Ileum-A Rare Case with Review of Literature." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 2 (2024): 92–96. https://doi.org/10.5281/zenodo.15372811.

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<strong>Abstract</strong> <strong>Background:</strong> Inflammatory fibroid polyp is a rare benign tumor located in the stomach and small bowel. These tumors arise within the submucosa of the gastrointestinal tract. <strong>Introduction:</strong> Inflammatory fibroid polyp (IFP) is a rare benign tumor which was initially describe by Vanek in 1949, termed as submucosa gastric granuloma with eosinophil.<sup>[1]</sup>Later on the term Inflammatory polyp was proposed by Helwig and Ranier in 1953.<sup>[2]</sup> The incidence of inflammatory polyp is very low i.e.  0.1%. The commonest site of involvement is gastric antrum and small bowel. We present the case of IFP in a 55 year old male patient to highlight the rarity of lesion and as well as characteristic microscopic features. <strong>Clinical Presentation:</strong> Depending on the location of the tumor, these neoplasm show classic histologic features. <strong>Case Report:</strong> We present a case of Inflammatory Fibroid Polyp arising from ileum in a 55year old male patient presented with intestinal obstruction. <strong>Conclusion:</strong> Inflammatory Fibroid Polyp is a rare benign tumor of GIT. Clinical presentation of this tumor depends on the site. Histopathological examination helps in the definitive diagnosis of this tumor.

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11

Grgov, Sasa, Vuka Katic, and Takanori Hattori. "Endoscopic resection of inflammatory gastric fibroid polyp: A case report." Srpski arhiv za celokupno lekarstvo 137, no. 9-10 (2009): 545–49. http://dx.doi.org/10.2298/sarh0910545g.

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Introduction An inflammatory fibroid polyp is a rare condition with frequent localization in the antrum of the stomach. Because of the localization in the bottom parts of the mucosa and submucosa, a histological diagnosis is difficult to establish at endoscopic biopsies. So, a correct diagnosis is histologically possible after surgical excision which is a common manner of treatment. Many authors have shown that endoscopic removal of an inflammatory fibroid polyp is possible. Case outline We are presenting a case of complete endoscopic resection of an inflammatory fibroid polyp of the stomach antrum in a 72-year-old patient. He complained of nausea, vomiting and loss of appetite. The polyp endoscopically looked like flat elevation with central umbilication, 16 mm in diameter and it was localized praepylorically. Pathohistologically, areas of severe epithelial dysplasia were verified at endoscopic biopsies which suggested early gastric cancer. Helicobacter pylori (H. pylori) infection was verified histologically and with rapid urease test. The patient was treated with triple eradication H. pylori therapy. Two months after the therapy, we decided to perform endoscopic resection of the polyp. We applied a suction technique of mucosal resection by which the polyp was completely resected. After complete endoscopic removal, the final diagnosis of an inflammatory fibroid polyp localised in the submucosa and mucosa of the antrum of the stomach was histologically made. On follow-ups, after 3, 6 and 12 months, there were no endoscopic and histological signs of either inflammatory fibroid polyp relapse, or recurrence of H. pylori infection. The patient had no dyspeptic symptoms. Conclusion We recommend an endoscopic method of resection as a therapy of choice for an inflammatory fibroid polyp of the stomach.

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12

Goto, Keisuke, Takuya Hirosaki, and Mariko Masubuchi. "Neurofibromatosis Type 1–Associated Inflammatory Polyp of the Gastrointestinal Tract." International Journal of Surgical Pathology 25, no. 1 (2016): 65–68. http://dx.doi.org/10.1177/1066896916648772.

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The entity known as “juvenile-like (inflammatory/hyperplastic) mucosal polyps of the gastrointestinal tract in neurofibromatosis type 1 (NF1)” was recently proposed, but is not well known. Here, we describe the characteristics of this entity in a surgically resected case. The hemorrhagic 2 × 1 cm–sized polyp was resected from the ascending colon of a 55-year-old male NF1 patient. The polyp was composed of characteristic multiple mucosal protrusions and submucosal elements that included vasculopathic changes. Histologically, this lesion was similar to an inflammatory fibroid polyp rather than juvenile or hyperplastic polyps. This disease could be a distinct entity, and “inflammatory vasculopathic polyp” would be a suitable name.

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13

Chan, John K. C. "GIST Versus Inflammatory Fibroid Polyp." International Journal of Surgical Pathology 9, no. 2 (2001): 147. http://dx.doi.org/10.1177/106689690100900209.

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14

Yamamoto, Toshiki, Takashi Hirai, Noriyoshi Okano, et al. "A Case of Gastric Inflammatory Fibroid Polyp." Progress of Digestive Endoscopy(1972) 46 (1995): 150–51. http://dx.doi.org/10.11641/pdensks.46.0_150.

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15

Saeki, Ichiro, Kimiya Takeshita, Masao Tani, Tooru Honda, Naoya Saito, and Mitsuo Endo. "Two Cases of Gastric Inflammatory Fibroid Polyp." Progress of Digestive Endoscopy(1972) 50 (1997): 262–63. http://dx.doi.org/10.11641/pdensks.50.0_262.

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16

Patel, Divya Gordhanbhai, Pragati Atulbhai Shah, Raj D. Shah, Minesh Gandhi, and Cherry Shah. "Inflammatory fibroid polyps of small and large intestine: Report of two cases." Indian Journal of Pathology and Oncology 11, no. 2 (2024): 172–75. http://dx.doi.org/10.18231/j.ijpo.2024.036.

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Inflammatory fibroid polyps (IFPs) are uncommon benign solitary mesenchymal neoplasms which may develop anywhere in the gastrointestinal tract. These submucosal lesions can occur in individuals of any age but are more frequently observed in the 6th or 7th decade of life. Although rarely associated with adenoma or adenocarcinoma, IFPs are typically managed through local excision. The clinical presentation varies depending on the anatomical location of the polyp. Gross examination typically reveals localized submucosal sessile polypoidal masses. Microscopically, IFPs are characterized by inflammatory cell infiltrate, spindle shaped cells and prominent capillaries. These benign lesions have unknown pathogenesis. Below mentioned are two case report of inflammatory fibroid polyps which lead to intussusception.

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17

Sánchez, Mario Martín, Víctor Domínguez Prieto, Siyuan Qian Zhang, et al. "Inflammatory Fibroid Polyp (Vanek’s Tumor): A Retrospective Multicentric Analysis of 67 Cases." Cancers 17, no. 7 (2025): 1209. https://doi.org/10.3390/cancers17071209.

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Objectives: Inflammatory fibroid polyps, also known as Vanek’s tumors, are rare benign lesions of the gastrointestinal tract. Although the exact cause remains unclear, several theories suggest an association with inflammatory processes and genetic factors. This study aims to present the largest cohort of inflammatory fibroid polyp cases to date, analyzing their clinical presentation, diagnostic methods, and treatment approaches. Materials and methods: A retrospective multicentric analysis was conducted on 67 patients diagnosed with inflammatory fibroid polyps between 2013 and 2023 across four hospitals. Clinical data regarding tumor location, size, symptoms, and treatment were collected. Non-parametric statistical tests, including the chi-square test, Cramér’s V coefficient, and the Mann–Whitney U test, were used to identify association between tumor characteristics, location, and treatment outcomes. Results: The cohort included 67 patients (58.2% female, median age 60 years). The stomach was the most common tumor site (47.8%), followed by the colon (32.8%), and small intestine (10.4%). The majority of patients (73.1%) were asymptomatic, while 9% experienced intestinal obstruction, all of which were located in the small intestine. Endoscopic resection was successful in 77.6% of cases, but surgical intervention was more frequently required for tumors in the small intestine. A significant association was found between larger tumor size, emergency presentation, intestinal location, and the need for surgery. Conclusions: Inflammatory fibroid polyps are commonly managed with endoscopic resection, particularly in gastric and colonic locations. However, small intestinal tumors more often need surgical treatment, especially when presenting with complications like intestinal obstruction.

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18

Shin, Kyung Sook, and June Sik Cho. "Inflammatory Fibroid Polyp of the Stomach." Journal of the Korean Radiological Society 41, no. 1 (1999): 113. http://dx.doi.org/10.3348/jkrs.1999.41.1.113.

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19

Santos, Gilda da Cunha, Venâncio A. F. Alves, Alda Wakamatsu, and Sérgio Zucoloto. "Inflammatory fibroid polyp: an immunohistochemical study." Arquivos de Gastroenterologia 41, no. 2 (2004): 104–7. http://dx.doi.org/10.1590/s0004-28032004000200007.

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BACKGROUND: Inflammatory fibroid polyp is a localized lesion, which arises in the submucosa of the gastrointestinal tract, most often in the stomach.Although it is generally believed to represent a reactive, nonneoplastic condition, its histogenesis remains controversial. AIM: To study inflammatory fibroid polyp by immunohistochemistry in an attempt to further clarify their histogenesis. MATERIAL AND METHODS: Nine cases were studied by immunohistochemistry using a panel of antibodies against smooth-muscle actin, vimentin, S-100 protein, factor VIII- R.Ag and macrophage (HAM-56). RESULTS: There was a strong diffuse positive staining pattern in the spindle cells with vimentin antibody. A patchy staining for smooth-muscle actin was observed in these cells. Immunophenotyping revealed a heterogeneous reaction with HAM-56. In edematous areas, HAM-56-positive cells show voluminous cytoplasm and reniform nuclei. In cell-rich areas, the HAM-56-positive cells had fusiform cytoplasm. Stains for S-100 and factor VIII RAg were negative in the proliferating elements. CONCLUSIONS: The present immunohistochemical study refutes the suggested neural or vascular nature of the lesion. The strong positivity for vimentin in all cases suggests a major component of spindle cells best recognizable as fibroblasts. These results would favor the existence of a span of morphological and immunohistochemical patterns possibly indicating evolutive phases of an inflammatory reaction.

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20

Jacobs, T. M., and A. L. Lambrianides. "Inflammatory fibroid polyp presenting as intussusception." Journal of Surgical Case Reports 2013, no. 2 (2013): rjt005. http://dx.doi.org/10.1093/jscr/rjt005.

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21

Adachi, Y., M. Mori, M. Iida, M. Tsuneyoshi, and K. Sugimachi. "Inflammatory Fibroid Polyp of the Stomach." Journal of Clinical Gastroenterology 15, no. 2 (1992): 154–58. http://dx.doi.org/10.1097/00004836-199209000-00015.

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22

Kolodziejczyk, Piotr, Takashi Yao, and Masazumi Tsuneyoshi. "Inflammatory Fibroid Polyp of the Stomach." American Journal of Surgical Pathology 17, no. 11 (1993): 1159–68. http://dx.doi.org/10.1097/00000478-199311000-00009.

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23

Paikos, D., J. Moschos, D. Tzilves, et al. "Inflammatory Fibroid Polyp or Vanek’s Tumour." Digestive Surgery 24, no. 3 (2007): 231–33. http://dx.doi.org/10.1159/000103326.

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24

Ishikura, Hiroshi, Fujio Sato, Ayako Naka, Takao Kodama, and Miki Aizawa. "INFLAMMATORY FIBROID POLYP OF THE STOMACH." Pathology International 36, no. 3 (1986): 327–35. http://dx.doi.org/10.1111/j.1440-1827.1986.tb01023.x.

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25

Costa, P. M., A. Marques, I. Távora, E. Oliveira, and M. Diaz. "Inflammatory fibroid polyp of the esophagus." Diseases of the Esophagus 13, no. 1 (2000): 75–79. http://dx.doi.org/10.1046/j.1442-2050.2000.00086.x.

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26

Fogt, Zimmerman, and Buyske. "Inflammatory fibroid polyp of the gallbladder." Histopathology 33, no. 6 (1998): 588–89. http://dx.doi.org/10.1046/j.1365-2559.1998.0525f.x.

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27

Stolte, M., and G. Finkenzeller. "Inflammatory Fibroid Polyp of the Stomach." Endoscopy 22, no. 05 (1990): 203–7. http://dx.doi.org/10.1055/s-2007-1012848.

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28

Pinto-Pais, Teresa, Sónia Fernandes, Luísa Proença, et al. "A Large Gastric Inflammatory Fibroid Polyp." GE Portuguese Journal of Gastroenterology 22, no. 2 (2015): 61–64. http://dx.doi.org/10.1016/j.jpge.2014.07.006.

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29

Albert, JG. "Inflammatory Fibroid Polyp within the Ileum." Video Journal and Encyclopedia of GI Endoscopy 1, no. 1 (2013): 239–40. http://dx.doi.org/10.1016/s2212-0971(13)70102-x.

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30

Assarian, Gary S., and A. Sundareson. "Inflammatory fibroid polyp of the ileum." Human Pathology 16, no. 3 (1985): 311–12. http://dx.doi.org/10.1016/s0046-8177(85)80019-8.

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31

De Foer, Bert, Bart Serrien, Edith Bleus, et al. "Inflammatory fibroid polyp of the ileum." Abdominal Imaging 18, no. 4 (1993): 363–65. http://dx.doi.org/10.1007/bf00201783.

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Iqbal, Sadat, Abu Hurairah, and Shahzad Iqbal. "Inflammatory Fibroid Polyp in the Duodenum." American Journal of Gastroenterology 112 (October 2017): S1373—S1374. http://dx.doi.org/10.14309/00000434-201710001-02521.

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Jha, Ritesh, Robert Tepper та Eugene S. Bonapace. "INFLAMMATORY FIBROID POLYP MIMICKING CROHNʼS DISEASE". American Journal of Gastroenterology 99 (жовтень 2004): S184. http://dx.doi.org/10.14309/00000434-200410001-00564.

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34

&NA;. "Inflammatory fibroid polyp of the stomach." Advances in Anatomic Pathology 5, no. 1 (1998): 47. http://dx.doi.org/10.1097/00125480-199801000-00038.

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35

Podder S. "An Unusual Case of Adult Intussusception - A Case Report." Journal of Sylhet Women’s Medical College 15, Number 1 (2025): 68–70. https://doi.org/10.47648/jswmc2025v15-01-26.

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Introduction: In Adults intussusception as a cause of small intestinal obstruction is a rare condition. Among the lead points for intussusception intestinal polyps are most common and also there are probabilities of malignant tumors which usually become greater from proximal to distal colon. Fibroid polyps are most uncommon benign pathology leading to intussusception of small bowel, presented in our case report. Case presentation: A 45 years old lady admitted in surgery ward of Sylhet Women’s Medical College Hospitalwith the features of small bowel obstruction for 5days. The abdominal ultrasonography report was suggestive of bowel mass resulting small bowel obstruction. Than multi axial contrast computed tomography of whole abdomen was done, which showed jejunoileal intussusception with intestinal obstruction. An intussusception with an intraluminal solid tumour at its lead point approximately 240cm distal to dudenojejunal flexure was found on exploratory laparotomy. Resection and anastomosisof affected bowel segment was done. Histopathological examination showed inflammatory fibroid polyp, ulcerated. Conclusion: In case of small bowel obstruction due to intussusception with a lead point of inflammatory fibroid polyp surgical approach is the most preferable solution though it is a benign condition.

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Tang, Yu, Xianfei Zhong, and Zhengyu Cheng. "Gastric hamartomatous inverted polyp coexisting with inflammatory fibroid polyp." Gastroenterología y Hepatología (English Edition) 47, no. 3 (2024): 270–71. http://dx.doi.org/10.1016/j.gastre.2023.03.010.

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Agarwal, Mohita, and Shalini Jaiswal. "Prolapsed Giant Cervical Fibroid Polyp." Journal of South Asian Federation of Obstetrics and Gynaecology 8, no. 1 (2016): 77–78. http://dx.doi.org/10.5005/jp-journals-10006-1391.

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ABSTRACT Giant cervical fibroid polyps causing diagnostic dilemma are rarely encountered in gynecologic practice. The objective of this case report is to document a case of huge cervical polyp large enough to cause prolapse of the otherwise normal uterus and cervix. A 35 years old multipara presented with heaviness in the vagina, pain in lower abdomen for 2 years and something coming out per vaginum, off and on vaginal bleeding and foul smelling discharge for 1 week. On local examination, grossly hypertrophied cervix was seen prolapsed outside the introitus and a large mass about 20 × 18 cm apparently arising from the posterior lip of the cervix. On per rectal examination, uterus was atrophied. Pap smear and showed only inflammatory changes with no evidence of malignancy. After four blood transfusion and control of local infection with systemic antibiotic, patient was taken for surgery. Postoperative recovery was uneventful histopathological report confirmed fibroid-polyp. Although giant cervical fibroid is rare, it may masquerade as neglected 3rd degree uterovaginal prolapse or massive enterocele as in our case. Proper evaluation is needed to make an accurate diagnosis, anticipate operative challenges and strike a judicious and rational approach about deciding the route of hysterectomy. How to cite this article Agarwal M, Singh S, Agarwal R, Jaiswal S. Prolapsed Giant Cervical Fibroid Polyp. J South Asian Feder Obst Gynae 2016;8(1):77-78.

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Hiroyoshi, Junko, Masami Minagawa, Junichi Togashi, Seiichirou Katahira, Tatsuya Kojima, and Yasushi Takeda. "A Gastric Inflammatory Fibroid Polyp with Hemorrhage." Nihon Gekakei Rengo Gakkaishi (Journal of Japanese College of Surgeons) 41, no. 2 (2016): 191–95. http://dx.doi.org/10.4030/jjcs.41.191.

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Wang, Huan, Tiejun Zhou, Cuiwei Zhang, Hao Li, and Muhan Lü. "Inflammatory fibroid polyp: an unusual cause of abdominal pain in the upper gastrointestinal tract A case report." Open Medicine 15, no. 1 (2020): 225–30. http://dx.doi.org/10.1515/med-2020-0033.

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AbstractInflammatory fibroid polyps (IFPs) tend to occur in the gastrointestinal tract, and they are rare and benign neoplasms. In general, IFPs often come from epithelial tissue. The gastric antrum is the most common location. Endoscopic ultrasound (EUS) often shows a predominantly hypoechoic mass with well-defined borders originating from the submucosal area. Here, we report the case of a 46-year-old woman with abdominal pain who underwent computed tomography (CT), endoscopic ultrasound and endoscopic submucosal dissection (ESD) of resected specimens; the diagnosis was ultimately an inflammatory fibroid polyp. She is currently in clinical remission.

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Bjerkehagen, Bodil, Kristin Aaberg, and Sonja E. Steigen. "Do Not Be Fooled by Fancy Mutations: Inflammatory Fibroid Polyps Can Harbor Mutations Similar to Those Found in GIST." Case Reports in Medicine 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/845801.

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Goal. Surgeons that remove a typical polyp from the stomach or small intestine should be reluctant to accept a diagnosis of GIST just because there is a mutation in platelet-derived growth factor receptor alfa (PDGFRA).Background. A subtype of gastric and intestinal polyps is denoted as inflammatory fibroid polyp (IFP). In some of these cases a mutation inPDGFRAis found, leading to the diagnosis of gastrointestinal stromal tumor (GIST).Study. This study includes two patients that had polyps removed from the ileum, and an extended investigation was performed with immunohistochemical staining and mutation analyses.Results. The tumors did not show typical immunohistochemical staining for markers used to diagnose GIST, but the mutation analysis revealed a mutation inPDGFRAexon 12. On the basis of the mutation analysis, both polyps were primarily diagnosed as GISTs, but the diagnosis was later changed to inflammatory fibroid polyp.Conclusion. It is important that both surgeons and pathologists be aware that IFP can harbor a mutation inPDGFRAwhere further treatment and follow-up is different with the two different diagnoses. A mutation analysis can be misleading when taken out of the context of clinical observations, histological characteristics and immunohistochemical staining.

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Güzel, Gökmen, and Muhammer Ergenç. "Recurrent Ileo-ileal Intussusception Caused by Inflammatory Fibroid Polyp: A Rare Case Report." Archives of Iranian Medicine 26, no. 6 (2023): 355–57. http://dx.doi.org/10.34172/aim.2023.53.

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An inflammatory fibroid polyp is a rare benign lesion of the gastrointestinal tract, which can cause obstruction or intussusception when it reaches a large diameter. We present a case of a 46-year-old female admitted to our clinic with recurrent ileus attacks. We performed segmental resection of the small bowel due to a 3-cm pedunculated polypoid lesion located in the terminal ileum that caused ileo-ileal intussusception and whose pathology was reported as an inflammatory fibroid polyp. In adults presenting with ileus, the possibility of intussusception should be kept in mind.

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Kimura, Nobuhiko, Michael Hight, James Liang, Ronald Willy, Kimberly Liang, and Jacob Camp. "Adult Intussusception Secondary to Inflammatory Fibroid Polyp." Western Journal of Emergency Medicine 16, no. 4 (2015): 581–82. http://dx.doi.org/10.5811/westjem.2015.4.26399.

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43

Adorisio, Ottavio, Emanuela Ceriati, Francesca Diomedi Camassei, Massimo Rollo, and Francesco De Peppo. "Inflammatory Fibroid Polyp of the Esophagogastric Junction." Journal of Pediatric Gastroenterology and Nutrition 64, no. 6 (2017): e154. http://dx.doi.org/10.1097/mpg.0000000000000977.

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44

Sugawara, Taro, Shintaro Sugita, Masatoshi Tateno, et al. "Colonic inflammatory fibroid polyp with PDGFRA expression." Pathology International 68, no. 3 (2017): 205–6. http://dx.doi.org/10.1111/pin.12625.

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Domínguez-Ferreras, Esther, Patricia Mármol-Vazquez, and Antonio Talegón-Meléndez. "Large inflammatory fibroid polyp of the stomach." European Journal of Radiology Extra 55, no. 2 (2005): 55–59. http://dx.doi.org/10.1016/j.ejrex.2005.05.008.

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Benchouk, Mohamed, Mohamed Ait Abdechikh, Tariq Ahbala, Elhabib Lammat, Khalid Rabbani, and Abdelouahed Louzi. "Acute Intestinal Intussusception in Adults Caused by an Inflammatory Fibroid Polyp: A Case Report." SAS Journal of Surgery 10, no. 12 (2024): 1373–77. https://doi.org/10.36347/sasjs.2024.v10i12.005.

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Abstract:

The inflammatory fibroid polyps (IFPs) are rare benign lesion originating in the submucosa of the digestive tract [1]. Its incidence is low, ranging between 0.6 and 2% [2]. Localization in the small intestine accounts for only 18% of cases [3], frequently presenting as acute intestinal intussusception. We report a case involving a 61-year-old woman with a history of cesarean section, presenting with diffuse abdominal pain, cessation of bowel movements and gas, and food-related vomiting. Physical examination revealed slightly distended abdomen and pelvic tenderness. Imaging studies demonstrated mechanical bowel obstruction due to terminal ileoileal intussusception with regular circumferential thickening of the invaginated bowel loops without signs of ischemia. Histopathological examination with immunohistochemical analysis confirmed the diagnosis of an inflammatory fibroid polyp without evidence of malignancy.

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Fazzio, Célia S. J., and Eveline B. Madeira. "Inflammatory fibroid polyp (Vanek’s polyp): a case report and literature review." Jornal Brasileiro de Patologia e Medicina Laboratorial 51, no. 2 (2015): 117–20. http://dx.doi.org/10.5935/1676-2444.20150021.

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Otake, Haruka, Hiroyuki Miyatani, Masahiro Hiruta, and Yukio Yoshida. "A case of inflammatory fibroid polyp of the ileum with preoperative histopathological diagnosis." Progress of Digestive Endoscopy 86, no. 1 (2015): 170–71. http://dx.doi.org/10.11641/pde.86.1_170.

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Talukder, Md Rajibul Haque, Md Noor A. Alam, Zahid Iqbal Jamal Uddin, and Nilufar Shabnam. "Jejunal inflammatory fibroid polyp: a rare cause of intussusception." Ibrahim Medical College Journal 9, no. 2 (2016): 58–60. http://dx.doi.org/10.3329/imcj.v9i2.28856.

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Inflammatory fibroid polyp is a benign and non-neoplastic condition of the gastro-intestinal tract, commonly affecting the gastric antrum, though it can affect any part of the gastro-intestinal tract. It is a submucosal, sessile, polypoid mass composed of myofbroblast like mesenchymal cells, numerous small blood vessels and marked inflammatory cell infiltrate mainly eosinophils. It commonly presents with intestinal obstruction or intussusception. We present here a case of recurrent episodes of small intestinal sub-acute obstruction due to intermittent intussusception associated with inflammatory ûbroid polyp of jejunum.Ibrahim Med. Coll. J. 2015; 9(2): 58-60

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Mohammad Shahid Iqbal, Mohammad Shahid Iqbal. "Inflammatory fibroid polyp of caecum. A case report." IOSR Journal of Dental and Medical Sciences 6, no. 3 (2013): 38–39. http://dx.doi.org/10.9790/0853-0633839.

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