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Journal articles on the topic 'Informatique Granulaire'

Author: Grafiati

Published: 7 July 2024

Last updated: 31 July 2025

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1

Tan, Chang, Qian Wang, and Fengmin Li. "Effects of microplastics on granular sludge: A review." E3S Web of Conferences 536 (2024): 02022. http://dx.doi.org/10.1051/e3sconf/202453602022.

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Biogranules are recently regarded as promising methods with intensive density and satisfying settleability for waste treatment and resource recovery. Wastewater treatment plants (WWTP) were regarded as “sinks” for Microplastics (MPs) and amount of MPs entrapped in the sludge. MPs have been reported to harm the granular characteristics and wastewater treatment efficiency. Previous research stated that the harmful effect on granular sludge is closely associated with the sizes and concentrations of MPs. However, there is still a lack of a comprehensive summary of granular characteristics variatio

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Valle, Nicolò. "Dual readout with capillary tubes – status and prospects." EPJ Web of Conferences 320 (2025): 00054. https://doi.org/10.1051/epjconf/202532000054.

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This paper discusses the ongoing development and testing of dual-readout fiber-based calorimeter demonstrators. An overview of the existing prototype will be presented, along with details on the assembly and integration strategies of the High-Resolution Highly-Granular Dual-Readout Demonstrator (HiDRa). A concise yet informative summary of simulation results and a perspective on upcoming beam tests will be discussed.

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Jia, Shengxin, and Veronica J. Santos. "Tactile Perception for Teleoperated Robotic Exploration within Granular Media." ACM Transactions on Human-Robot Interaction 10, no. 4 (2021): 1–27. http://dx.doi.org/10.1145/3459996.

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The sense of touch is essential for locating buried objects when vision-based approaches are limited. We present an approach for tactile perception when sensorized robot fingertips are used to directly interact with granular media particles in teleoperated systems. We evaluate the effects of linear and nonlinear classifier model architectures and three tactile sensor modalities (vibration, internal fluid pressure, fingerpad deformation) on the accuracy of estimates of fingertip contact state. We propose an architecture called the Sparse-Fusion Recurrent Neural Network (SF-RNN) in which sparse

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Vannecke, Thomas P. W., George Wells, Nathalie Hubaux, Eberhard Morgenroth, and Eveline I. P. Volcke. "Considering microbial and aggregate heterogeneity in biofilm reactor models: how far do we need to go?" Water Science and Technology 72, no. 10 (2015): 1692–99. http://dx.doi.org/10.2166/wst.2015.389.

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A model describing a given system should be as simple as possible – but not simpler. The appropriate level of complexity depends both on the type of system and on the intended use of the model. This paper addresses the critical question of which purposes justify increased complexity of biofilm (reactor) models. Additional model features compared to conventional models considered are: (1) the inclusion of microbial diversity, distinguishing between different species performing the same function; and (2) the distinction between flocs and granules in putatively granular sludge reactors. With a mu

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Belyaeva, I. Yu, L. A. Ostrovsky, and V. Yu Zaitsev. "Microstructure induced nonlinearity of unconsolidated rocks as related to seismic diagnostic problems." Nonlinear Processes in Geophysics 4, no. 1 (1997): 1–10. http://dx.doi.org/10.5194/npg-4-1-1997.

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Abstract. Manifestations of the so-called structure induced nonlinearity are considered for the case of a granular medium, the latter being a generally accepted model of nonconsolidated rocks in seismics. The consideration is carried out using the medium model in the form of the "ideal" random packing of spherical elastic granules in which the interparticle space can be filled with a fluid. A physical equation of such a medium is derived; the dependencies of nonlinear parameters on the grain material elastic moduli, the fluid compressibility and the initial medium strain are analyzed. The infl

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Timofeeva, L. A., M. G. Tukhbatullin, and A. N. Sencha. "Ultrasonic Elastography in the Differential Diagnosis of Thyroid Nodular Patholog." Kuban Scientific Medical Bulletin 26, no. 4 (2019): 45–55. http://dx.doi.org/10.25207/1608-6228-2019-26-4-45-55.

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Aim.In this study, we set out to determine the informative value of multi-parametric ultrasound examination using ultrasound elastography in the differential diagnosis of thyroid nodular neoplasms.Materialsand methods. We analysed 229 multi-parametric ultrasound examinations of patients in the preoperative period in order to assess the effectiveness of strain elastography (SE) and shear wave elastography (SWE) drawing on the example of ARFI and Strain Ratio. Two patient groups were formed. The fi rst group (N1=93) included patients with thyroid cancer, whereas the second one (N2=136) was compo

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Hung, Tawny, Richard Ian Crawford, and Magdalena Martinka. "Degree of Histologic Inflammation in Lupus Erythematosus and Direct Immunofluorescence Results: Red and Inflamed Lesions Do Not Increase the Chances of Getting a Bright Band." Journal of Cutaneous Medicine and Surgery 17, no. 1 (2013): 22–26. http://dx.doi.org/10.2310/7750.2012.12032.

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Background: In the diagnostic work-up of lupus erythematosus (LE), direct immunofluoresence (DIF) examination could be helpful. Classically, clinically red lesions are targeted by clinicians in the hope of yielding an informative DIF result. However, the investigative correlation between the degree of inflammation and DIF positivity has never been published in the literature. Objective: In this study, we sought to discover if histologically inflamed lesions correlated with DIF positivity results. Method: We studied 112 lesions histologically consistent with LE and correlated the degree of hist

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Fasan, Annette, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach, and Susanne Schnittger. "STAT3 Mutations in Large Granular Lymphocytic Leukemia." Blood 120, no. 21 (2012): 1606. http://dx.doi.org/10.1182/blood.v120.21.1606.1606.

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Abstract Abstract 1606 Introduction: Large granular lymphocytic leukemia (LGL leukemia) is a rare lymphoproliferative disorder characterized by the presence of increased numbers of LGL cells in the peripheral blood. Discrimination of LGL leukemia and reactive T-cell processes is difficult and a matter of controversial discussion. Very recently, somatic STAT3 mutations located in the Src homology 2 domain (SH2 domain) have been described with a high frequency of 40% in T-cell LGL (T-LGL) leukemia (Koskela et al., 2012) and 30% in chronic NK-cell lymphoproliferative disorder (CLPD-NK) (Jerez et

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Kao, Szu-Yu Zoe, M. Shane Tutwiler, Donatus U. Ekwueme, and Benedict I. Truman. "Better data for decision-making through Bayesian imputation of suppressed provisional COVID-19 death counts." PLOS ONE 18, no. 8 (2023): e0288961. http://dx.doi.org/10.1371/journal.pone.0288961.

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Purpose To facilitate use of timely, granular, and publicly available data on COVID-19 mortality, we provide a method for imputing suppressed COVID-19 death counts in the National Center for Health Statistic’s 2020 provisional mortality data by quarter, county, and age. Methods We used a Bayesian approach to impute suppressed COVID-19 death counts by quarter, county, and age in provisional data for 3,138 US counties. Our model accounts for multilevel data structures; numerous zero death counts among persons aged <50 years, rural counties, early quarters in 2020; highly right-skewed distribu

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Hefni, Yasser Kamal. "Hydrophobic Zinc Oxide Nanocomposites for Consolidation and Protection of Quartzite Sculptures: A Case Study." Journal of Nano Research 63 (June 2020): 64–75. http://dx.doi.org/10.4028/www.scientific.net/jnanor.63.64.

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Quartzite sculptures are considered some of the most impressive and informative archaeological remains which have been found in the most of Egyptian archaeological sites. Regrettably, quartzite sculptures suffer from many deterioration aspects such as granular disintegration, scaling, cracking, efflorescence, soiling, microbiological colonization. Water is the main aggressive deterioration factor of stones and stone-based monuments, as in addition to its direct role in deterioration mechanisms, it plays as a catalyst in the physicochemical and microbiological deterioration processes.During the

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Gresser, Melissa, Dominik Brehl, Marc David Rabe, and Bernard Bäker. "Optimization of the Design of Diagnostic Systems through Requirement-Based Feature Selection." International Journal of Electronics and Electrical Engineering 9, no. 2 (2021): 26–35. http://dx.doi.org/10.18178/ijeee.9.2.26-35.

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The classification of faults based on available diagnostic information in large complex mechatronic systems is a well-studied research subject. One challenge is the classification of faults with missing or ambiguous diagnostic information present. In real-world applications, this has the effect of misclassified faults, resulting in costly replacements of functional components. As even the acquisition of diagnostic information is afflicted with costs and part of the diagnostic functions are mandatory, the design of diagnostic content at an early system development stage is essential. The paper

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Banfi, Fabrizio. "HBIM, 3D drawing and virtual reality for archaeological sites and ancient ruins." Virtual Archaeology Review 11, no. 23 (2020): 16. http://dx.doi.org/10.4995/var.2020.12416.

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<p class="VARAbstract">Data collection, documentation and analysis of the traces of ancient ruins and archaeological sites represent an inestimable value to be handed down to future generations. Thanks to the development of new technologies in the field of computer graphics, Building Information Modelling (BIM), Virtual Reality (VR) and three-dimensional (3D) digital survey, this research proposes new levels of interactivity between users and virtual environments capable of communicating the tangible and intangible values of remains of ancient ruins. In this particular field of developme

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Niftaliev, Sabukhi I., Yuriy S. Peregudov, Olga A. Kozaderova, and Kseniya B. Kim. "ENTHALPY OF INTERACTION OF ION-EXCHANGE HETEROGENEOUS MEMBRANES AND THEIR GRANULAR ANALOGUES WITH AMMONIUM NITRATE SOLUTION." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENIY KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 59, no. 7 (2018): 29. http://dx.doi.org/10.6060/tcct.20165907.5391.

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Ion-exchange membranes are widely used for extraction, separation and concentration of aqueous nitrogen-containing solutions. In the study the heterogeneous ion-exchange membranes of cationic type- MK-40, Ralex CM (H) -PP, MK-41 – and anionic type - MA-41, Ralex AM (H) -PP and also their granular analogues – cation exchanger KУ-2·8 and anion exchanger AB-17·8 were used. Sorption of nitrate ions and ammonium ions was conducted from the ammonium nitrate solution with concentration of 0.012 mole / dm³. To determine sorption thermochemical characteristics of the studied ions the calorimetric metho

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Battiwalla, Minoo, Paul K. Wallace, Laurie A. Ford, and Maria R. Baer. "Clinical and Pathological Presentation of T-Cell Large Granular Lymphocyte Proliferations (T-LGL): A Single Institution Experience." Blood 104, no. 11 (2004): 3865. http://dx.doi.org/10.1182/blood.v104.11.3865.3865.

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Abstract Proliferations of T-cell large granular lymphocytes (T-LGL) are a rare and heterogeneous disease entity characterized by a chronic course, cytopenias and circulating cytotoxic T lymphocytes. We present the results of a single institution retrospective review of the clinical presentation of T-LGL proliferations. A total of 23 patients evaluated for cytopenias were identified as having T-LGL by flow cytometry, ten male and thirteen female, with a median age of 67 years at diagnosis. Twelve patients had a prior malignancy (non-Hodgkins lymphoma=4, MDS/AML=4, breast cancer=2, squamous cel

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Chen, Dung-Tsa, Wenyaw Chan, Zachary J. Thompson, et al. "Utilization of target lesion heterogeneity for treatment efficacy assessment in late stage lung cancer." PLOS ONE 16, no. 7 (2021): e0252041. http://dx.doi.org/10.1371/journal.pone.0252041.

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Rationale Recent studies have discovered several unique tumor response subgroups outside of response classification by Response Evaluation Criteria for Solid Tumors (RECIST), such as mixed response and oligometastasis. These subtypes have a distinctive property, lesion heterogeneity defined as diversity of tumor growth profiles in RECIST target lesions. Furthermore, many cancer clinical trials have been activated to evaluate various treatment options for heterogeneity-related subgroups (e.g., 29 trials so far listed in clinicaltrials.gov for cancer patients with oligometastasis). Some of the t

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Loganathan, Paripurnanda, Jaya Kandasamy, Harsha Ratnaweera, and Saravanamuthu Vigneswaran. "The Incorporation of Adsorbents with Contrasting Properties into the Soil Substrate for the Removal of Multiple Pollutants in Stormwater Treatment for the Reuse of Water—A Review." Water 17, no. 13 (2025): 2007. https://doi.org/10.3390/w17132007.

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Stormwater carries significant amounts of pollutants—including metals, microorganisms, organic micropollutants, and nutrients—from land surfaces into nearby water bodies, leading to water quality deterioration and threats to both human health and ecosystems. The removal of these contaminants is essential not only for environmental protection, but also to enable the reuse of treated water for various beneficial applications. Common treatment methods include bioretention systems, biofiltration, constructed wetlands, rain gardens, swales, and permeable pavements. To improve pollutant removal effi

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Chekhovska, G. S. "ROLE OF DERMATOSCOPY IN CHRONIC DERMATOSES DIAGNOSIS." International Medical Journal, no. 2 (July 15, 2020): 53–56. http://dx.doi.org/10.37436/2308-5274-2020-2-11.

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Dermatoscopy is a valuable auxiliary non−invasive method used in the diagnosis of inflammatory, parasitic and viral skin diseases. Treatment of dermatoses is based on the results of analysis of melanin, follicular−horny and vascular components. Diagnosis begins with polarized dermatoscopy and then progresses to non−polarized using immersion fluid. At dermatoscopic inspection of a psoriatic plaque the point vessels evenly distributed along all the surface (a symptom of "scattered red pepper") are noted. Eczema is characterized by focal accumulation of blood vessels in the form of dots, peeling,

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Brumana, R., P. Condoleo, A. Grimoldi, and M. Previtali. "TOWARDS A SEMANTIC BASED HUB PLATFORM OF VAULTED SYSTEMS: HBIM MEETS A GEODB." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-2/W11 (May 4, 2019): 301–8. http://dx.doi.org/10.5194/isprs-archives-xlii-2-w11-301-2019.

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<p><strong>Abstract.</strong> In the last years many efforts have been invested in the cultural heritage digitization: surveying, modelling, diagnostic analysis and historic data collection. Nowadays, this effort is finalized in many cases towards the Historical Building Information Modelling. The number of informative models testifying the multifaceted richness and unicity of the architectural heritage and its components is progressively increasing. Information and Model are generally acquired under researches and analysis phases addressed to the preservation and restoration

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PIWOWARCZYK, RENATA, KAROLINA RURAŻ, YULIYA KRASYLENKO, JUSTYNA KASIŃSKA, and ÓSCAR SÁNCHEZ PEDRAJA. "Seed micromorphology of representatives of holoparasitic Orobanchaceae genera from the Caucasus region and its taxonomic significance." Phytotaxa 432, no. 3 (2020): 223–51. http://dx.doi.org/10.11646/phytotaxa.432.3.1.

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Obligate parasitic plant species from the Orobanchaceae family belong to the most critical genera of world flora. Due to their strongly reduced vegetative organ architecture, there arise many difficulties and mistakes in species identification, and extra characteristics of systematic importance are required. Seed micromorphology is a highly informative taxonomic criterion that helps to resolve ambiguities in plant taxonomy and evolution, and has proved to be a valuable complementary tool for Orobanchaceae species identification. In this study, seeds of 43 holoparasitic species from the Cistanc

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Bou-Sarkis, Abdo, Etienne Paul, Elisabeth Girbal-Neuhauser, Nicolas Derlon, and Yolaine Bessiere. "Detection of Gel-Forming Polymers via Calcium Crosslinking, Applied to the Screening of Extracellular Polymeric Substances Extracted from Biological Aggregates." Gels 9, no. 2 (2023): 157. http://dx.doi.org/10.3390/gels9020157.

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The valorization of biological aggregates through the extraction of hydrogel-forming polymers can enhance the economics and sustainability of various processes in which bacteria are involved in organic waste transformation, such as wastewater treatment. Achieving these goals requires the development of a method capable of detecting the presence of gel-forming polymers in complex mixtures containing biopolymers that are most often unknown and uncharacterized. A miniaturized screening method capable of detecting gelation via ionic crosslinking using only 1 to 3 mg of the tested samples (commerci

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Zhang, Yue, Jincheng Shen, Tina M. Willson, et al. "145. Comparing Antibiotic Use Across Inpatient Facilities with Different Antibiotic Stewardship Typologies using Machine Learning and Joint Modeling Approach." Open Forum Infectious Diseases 8, Supplement_1 (2021): S185. http://dx.doi.org/10.1093/ofid/ofab466.347.

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Abstract Background Hospital antibiotic stewardship programs (ASP) aim to promote the appropriate use of antimicrobials (including antibiotics) and play a critical role in controlling antibiotic costs and antibiotic-resistant bacterial infection risk, and improving patient outcomes. However, unlike other health care quality improvement intervention programs, the ASP implementation strategies vary among healthcare facilities, and little is known about whether different types of ASP implementation will lead to the shifting of antibiotic drug use from one class to another. Methods We proposed an

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Blake, Nathan, Matthew Walker, K. E. ArunKumar, Domingo Mata-Padrino, Ida Holaskova, and Matthew E. Wilson. "PSXI-25 Re-characterizing beef cattle water intake." Journal of Animal Science 102, Supplement_3 (2024): 770–71. http://dx.doi.org/10.1093/jas/skae234.868.

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Abstract In the face of a changing climate and growing population, sustainable use of freshwater resources is paramount. Animal agriculture is often viewed as an antagonistic force working against freshwater resource preservation. However, assumptions of water use in beef cattle have cause to be reevaluated. The current published standards for beef cattle water intake were developed from data collected in 1956. Rapid genetic advancement in performance and increasing pressure on animal agriculture to reduce water usage demand that the water intake profiles of cattle be recharacterized. Recently

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Cunningham, Eoghan M., and Julia D. Sigwart. "Environmentally Accurate Microplastic Levels and Their Absence from Exposure Studies." Integrative and Comparative Biology 59, no. 6 (2019): 1485–96. http://dx.doi.org/10.1093/icb/icz068.

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Abstract Microplastics (synthetic polymers; &lt;5 mm) are ubiquitous, in the environment and in the news. The associated effects of microplastics on flora and fauna are currently only established through laboratory-based exposure trials; however, such studies have come under scrutiny for employing excessive concentrations with little environmental relevance. This critical review is intended to summarize key issues and approaches for those who are considering the need for local microplastics research, both in terms of environmental pollution and the impacts on aquatic species. A meta-analys

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YANG, KUN L., JIA Y. LIN, GUANG-MEI LI, TAIHUI LI, and ZHU L. YANG. "Rediscovering Leucoagaricus sinicus, with the recognition of Leucoagaricus and Leucocoprinus as separate genera, and two new genera in Agaricaceae (Basidiomycota)." Phytotaxa 676, no. 3 (2024): 199–255. https://doi.org/10.11646/phytotaxa.676.3.1.

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An agaric belonging to the Leucoagaricus-Leucocoprinus group (AC group) of Agaricaceae s. l., commonly found in South China, was usually identified as Leucoagaricus lacrymans or Lepiota shixingensis in previous researches. However, as this agaric is also close to La. sinicus and the phylogeny of the AC group has not been resolved, its taxonomic position has not been elucidated. In this study, by reconstructing the phylogeny of the AC group and its closely related genera based on four DNA loci (ITS, nrLSU, rpb2, and tef-1α), the AC group is resolved as polyphyletic but formed a monophyletic gro

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Calafato, D., Y. Tang, G. Rukhovich, et al. "P02.23.A SPATIAL PROFILING OF THE MYELOID COMPARTMENT IN MENINGIOMA REVEALS DISTINCT PHENOTYPIC HETEROGENEITY ACROSS METHYLATION CLASSES." Neuro-Oncology 26, Supplement_5 (2024): v40. http://dx.doi.org/10.1093/neuonc/noae144.126.

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Abstract BACKGROUND Recent advances in neuro-oncology highlighted the meninges as an important immunological hub at the crossroads between systemic immunity and the central nervous system. Meningiomas are predominantly benign tumors arising from meningeal cells. However, about 20% are high-grade cases, commonly refractory to standard treatment, showing high recurrence rates. Methylation-based classification has crucially improved meningioma patient stratification. However, the biological processes that govern differences between these classes remain unknown. Here, we investigate the role of di

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AL- Mudallal, Subh S., and Huda N. Jasim. "Evaluation of Bcl 2 and Ki 67 expression in Chronic Lymphocytic Leukemia ." Journal of the Faculty of Medicine Baghdad 54, no. 4 (2013): 335–39. http://dx.doi.org/10.32007/jfacmedbagdad.544698.

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Background :Chronic lymphocytic leukemia (CLL) is a low-grade B-lineage lymphoid malignancy. Both Ki-67 which is a large nuclear protein associated with cell proliferation and Bcl-2 which is an anti-apoptotic protein which is associated with dysregulation of the intrinsic apoptotic pathway , were thoroughly investigated in many cancer patients particularly in hemopoietic malignancies . Patients, materials and methods: This retrospective study was conducted from November 2009 to May 2010 , on fifty formaline fixed paraffin embedded blocks of CLL cases retrieved from Medical City Teaching

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Baymatov, Valery N., and Galiya R. Shakirova. "Reactive changes in connective tissue structures in peripheral nerve of sheep with liver pathology." Veterinariya, Zootekhniya i Biotekhnologiya 4, no. 113 (2023): 21–37. http://dx.doi.org/10.36871/vet.zoo.bio.202304002.

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Experimental studies were carried out on sheep using a tetramethane model of hepatosis. Ultrastructural data made it possible to characterize morphofunctional changes in peripheral nerves in sheep, in particular, in myelinated and non-myelinated fibers, neurolemmocytes, and connective tissue structures. The pathological process in the peripheral nervous system initiates a combined pathology of the abdominal organs. This is due to the commonality of their innervation with the dorsal and ventral vagus, celiac, phrenic nerves, and branches of the solar plexus. A decrease in the trophic function o

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Spangler, Matthew L. "461 Machine learning and AI to improve genetic prediction in beef cattle: Potential uses and misuses." Journal of Animal Science 102, Supplement_3 (2024): 296–97. http://dx.doi.org/10.1093/jas/skae234.339.

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Abstract The current objective is to discuss if and where machine learning (ML) and artificial intelligence (AI) fit in the genetic prediction toolbox. Critical to the discussion is recognizing that, by definition, models currently employed for routine genetic prediction are part of the ML family, albeit linear as opposed to deep, and that ML fits under the more general umbrella of AI. Henderson’s Mixed Model Equations (MME) have served the animal breeding and genetic community well for several decades and have proven useful at predicting the additive genetic merit of animals. Moreover, extens

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Zhang, Ze, Brock C. Christensen, and Lucas A. Salas. "Abstract 1212: ExTIME: Extended tumor immune micro-environment cell mixture deconvolution using DNA methylation and a novel tumor-site-specific hierarchical approach." Cancer Research 82, no. 12_Supplement (2022): 1212. http://dx.doi.org/10.1158/1538-7445.am2022-1212.

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Abstract Background: The solid tumor microenvironment is heterogeneous and varies in composition by tumor type. Previous gene expression and DNA methylation deconvolution approaches for tumor micro-environment have had some success for major cell types. However, existing methods lack specificity to tumor type and detailed cell types. We developed 21 tumor-specific DNA methylation-based libraries. We employed a novel hierarchical approach in 3 major tumor microenvironment components (tumor, angiogenic, immune) to profile 17 cell types (see methods below). Methods: DNA methylation data on tumor

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Lychman, V. O., M. G. Skikevich, L. I. Voloshyna, V. M. Havryl’iev, and D. S. Avetikov. "CYTOLOGICAL CHARACTERISTICS OF REGENERATIVE PROCESSES IN PURULENT WOUND DEPENDING ON THE TIME OF SURGERY (MORNING EVENING) AND CHRONOTYPE OF PATIENTS (MORNING AND EVENING CHRONOTYPE)." Ukrainian Dental Almanac, no. 1 (March 28, 2022): 29–32. http://dx.doi.org/10.31718/2409-0255.1.2022.05.

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Healing of postoperative wounds is a staged process. At the early stage of the wound process is characterized by the presence of a large number of unchanged and altered erythrocytes, the latter are characterized by shrinkage, change in shape, the formation of clusters. Hemorrhages in a wound and the initial phenomena of an inflammation are defined. In the period of regeneration of wound healing, inflammatory phenomena gradually disappear, and regenerative processes are increasingly developed. n the study of the dynamics of healing of postoperative wounds, the most informative is the method of

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Tadanki, Arihanth Srikar, H. Surya Prakash Rao, and U. Deva Priyakumar. "Dissecting errors in machine learning for retrosynthesis: a granular metric framework and a transformer-based model for more informative predictions." Digital Discovery, 2025. https://doi.org/10.1039/d4dd00263f.

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Introducing novel evaluation metrics for retrosynthesis that address dataset imperfections using custom scoring metrics and presenting SynFormer, a transformer-based model that achieves state-of-the-art accuracy efficiently without pre-training.

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Gillard, Jonathan, Vincent Knight, Kendal Smith, and Henry Wilde. "Optimising healthcare queues: a case study on chronic respiratory illness." IMA Journal of Management Mathematics, January 9, 2025. https://doi.org/10.1093/imaman/dpaf002.

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Abstract This study employs a data-driven approach to assess the evolving resource needs of chronic obstructive pulmonary disease (COPD) patients, exploring the impact on the hospital system. It integrates segmentation, operational queuing theory, and parameter recovery from incomplete data to overcome limitations in fine-grained data availability, yielding operational insights using only administrative data. Initiating with a population clustering from granular data, the paper utilizes a multi-class $M/M/c$ model, extracting parameters through parameterization and Wasserstein distance. This m

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Gren, Simon, and Elena Leuschner. "Outcome Isn’t Everything: Electoral Consequences of Implementing or Withdrawing Unpopular Policies." Political Behavior, May 5, 2024. http://dx.doi.org/10.1007/s11109-024-09936-8.

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AbstractIncumbents often make unpopular policy decisions. But can they remedy their negative electoral consequences? We extend the wide literature concerning retrospective voting to the case of unpopular policies and examine whether voters reward a responsive withdrawal of an unpopular policy proposal or punish the disclosed policy intention despite the withdrawal. To test this, we use granular data on Swedish local election results from 2002 to 2018 and the case of widely unpopular school closure proposals, some of which were implemented and others not. We exploit within municipality variatio

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Ajayi, Alex A., Jesus E. Delgado, Ryan Fechner, and Jo-Ida C. Hansen. "BIM-181: Revising the Public Domain “Basic Interest Markers” Using Item Response Theory." Journal of Career Assessment, November 11, 2024. http://dx.doi.org/10.1177/10690727241296110.

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The present study investigated the psychometric properties of the Basic Interest Markers (BIM), a public-domain broadband measure of basic interests. Unlike broader general interest frameworks such as Holland’s RIASEC types, basic interests represent more specific content domains and provide a granular view of vocational preferences and inclinations. We used Item Response Theory (IRT) to perform item analysis to identify the most informative items in each BIM scale and, by extension, reduce scale lengths. In addition, we used confirmatory factor analysis to test model fit for the BIM scales an

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Finesso, Giovanni E., Ross A. McDevitt, Roshni Roy, et al. "Impact of Large Granular Lymphocyte Leukemia on Blood DNA Methylation and Epigenetic Clock Modeling in Fischer 344 Rats." Journals of Gerontology: Series A, October 28, 2021. http://dx.doi.org/10.1093/gerona/glab328.

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Abstract Age-dependent differences in methylation at specific cytosine–guanine (CpG) sites have been used in “epigenetic clock” formulas to predict age. Deviations of epigenetic age from chronological age are informative of health status and are associated with adverse health outcomes, including mortality. In most cases, epigenetic clocks are performed on methylation from DNA extracted from circulating blood cells. However, the effect of neoplastic cells in the circulation on estimation and interpretation of epigenetic clocks is not well understood. Here, we explored this using Fischer 344 (F3

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Yu, Mingyan, Zhenke Wu, Margaret Hicken, and Michael R. Elliott. "A Bayesian Approach to Modeling Variance of Intensive Longitudinal Biomarker Data as a Predictor of Health Outcomes." Statistics in Medicine, November 14, 2024. http://dx.doi.org/10.1002/sim.10281.

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ABSTRACTIntensive longitudinal biomarker data are increasingly common in scientific studies that seek temporally granular understanding of the role of behavioral and physiological factors in relation to outcomes of interest. Intensive longitudinal biomarker data, such as those obtained from wearable devices, are often obtained at a high frequency typically resulting in several hundred to thousand observations per individual measured over minutes, hours, or days. Often in longitudinal studies, the primary focus is on relating the means of biomarker trajectories to an outcome, and the variances

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Vader, Vinita, and Gerard Saucier. "High‐dimensionality structure in English‐language personality type‐nouns." Journal of Personality, May 18, 2024. http://dx.doi.org/10.1111/jopy.12940.

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AbstractObjectivePast applications of the lexical approach to type‐noun personality structures have yielded different results compared with those generated for adjectival personality structures, since then new methods have arisen for identifying robust higher‐dimensionality structure in data. This research aims to identify an optimal taxonomy of English language type‐nouns.MethodCurrent study reanalyzed 372 type‐nouns from a previous study emphasizing robustness across methodological variations (original vs. ipsatized data, oblique vs. orthogonal rotations, convergence between male and female

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Yan, April Yujie, Traci Jenelle Speed, and Casey Overby Taylor. "Relapse prediction using wearable data through convolutional autoencoders and clustering for patients with psychotic disorders." Scientific Reports 15, no. 1 (2025). https://doi.org/10.1038/s41598-025-03856-1.

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Abstract Relapse of psychotic disorders occurs commonly even after appropriate treatment. Digital phenotyping becomes essential to achieve remote monitoring for mental conditions. We applied a personalized approach using neural-network-based anomaly detection and clustering to predict relapse for patients with psychotic disorders. We used a dataset provided by e-Prevention grand challenge (SPGC), containing physiological signals for 10 patients monitored over 2.5 years (relapse events: 560 vs. non-relapse events: 2139). We created 2-dimensional multivariate time-series profiles containing acti

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Vasconcelos, Helena, Gagan Bansal, Adam Fourney, Q. Vera Liao, and Jennifer Wortman Vaughan. "Generation Probabilities Are Not Enough: Uncertainty Highlighting in AI Code Completions." ACM Transactions on Computer-Human Interaction, October 29, 2024. http://dx.doi.org/10.1145/3702320.

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Large-scale generative models have enabled the development of AI-powered code completion tools to assist programmers in writing code. Like all AI-powered tools, these code completion tools are not always accurate and can introduce bugs or even security vulnerabilities into code if not properly detected and corrected by a human programmer. One technique that has been proposed and implemented to help programmers locate potential errors is to highlight uncertain tokens. However, little is known about the effectiveness of this technique. Through a mixed-methods study with 30 programmers, we compar

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Alsharhan, Hind, Fay Alkurd, Mohammad A. Ebrahim, et al. "Cardiovascular Gaucher Disease Type 3c Associated With Homozygous Asp448His GBA1 Variant: First Case Series From Kuwait." American Journal of Medical Genetics Part A, June 9, 2025. https://doi.org/10.1002/ajmg.a.64148.

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ABSTRACTCardiac involvement in Gaucher disease (GD) is an uncommon feature, most often associated with the homozygous Asp448His (D409H) variant in GBA1 and typically presents with valvular and pericardial calcifications or myocardial infiltration. To date, approximately 132 individuals with this cardiovascular phenotype (GDIIIc) have been reported, with limited representation from the Middle East. This study reports the first cohort from Kuwait, involving five individuals from three unrelated Middle Eastern families, all with molecularly confirmed homozygous Asp448His variants. All individuals

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Huang, Wenxin, Xuemei Jia, Xian Zhong, Xiao Wang, Kui Jiang, and Zheng Wang. "Beyond the Parts: Learning Coarse-to-Fine Adaptive Alignment Representation for Person Search." ACM Transactions on Multimedia Computing, Communications, and Applications, October 8, 2022. http://dx.doi.org/10.1145/3565886.

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Person search is a time-consuming computer vision task that entails locating and recognizing query people in scenic pictures. Body components are commonly mismatched during matching due to position variation, occlusions, and partially absent body parts, resulting in unsatisfactory person search results. Existing approaches for extracting local characteristics of the human body using keypoint information are unable to handle the search job when distinct body parts are misaligned, ignoring to exploit multiple granularities, which is crucial in the person search process. Moreover, the alignment l

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Checchi, Francesco, Adrienne Testa, Amy Gimma, Emilie Koum-Besson, and Abdihamid Warsame. "A method for small-area estimation of population mortality in settings affected by crises." Population Health Metrics 20, no. 1 (2022). http://dx.doi.org/10.1186/s12963-022-00283-6.

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Abstract Background Populations affected by crises (armed conflict, food insecurity, natural disasters) are poorly covered by demographic surveillance. As such, crisis-wide estimation of population mortality is extremely challenging, resulting in a lack of evidence to inform humanitarian response and conflict resolution. Methods We describe here a ‘small-area estimation’ method to circumvent these data gaps and quantify both total and excess (i.e. crisis-attributable) death rates and tolls, both overall and for granular geographic (e.g. district) and time (e.g. month) strata. The method is bas

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Javidnia, Monica, Lakshmi Arbatti, Abhishek Hosamath, Shirley W. Eberly, David Oakes, and Ira Shoulson. "Predictive Value of Verbatim Parkinson’s Disease Patient-Reported Symptoms of Postural Instability and Falling." Journal of Parkinson's Disease, July 7, 2021, 1–8. http://dx.doi.org/10.3233/jpd-212636.

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Background: Postural instability is an intractable sign of Parkinson’s disease, associated with poor disease prognosis, fall risk, and decreased quality of life. Objective: 1) Characterize verbatim reports of postural instability and associated symptoms (gait disorder, balance, falling, freezing, and posture), 2) compare reports with responses to three pre-specified questions from Part II of the Movement Disorder Society Unified Parkinson Disease Rating Scale (MDS-UPDRS), and 3) examine postural instability symptoms and MDS-UPDRS responses as predictors of future falls. Methods: Fox Insight re

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Röding, Magnus, Zheng Ma, and Salvatore Torquato. "Predicting permeability via statistical learning on higher-order microstructural information." Scientific Reports 10, no. 1 (2020). http://dx.doi.org/10.1038/s41598-020-72085-5.

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Abstract Quantitative structure–property relationships are crucial for the understanding and prediction of the physical properties of complex materials. For fluid flow in porous materials, characterizing the geometry of the pore microstructure facilitates prediction of permeability, a key property that has been extensively studied in material science, geophysics and chemical engineering. In this work, we study the predictability of different structural descriptors via both linear regressions and neural networks. A large data set of 30,000 virtual, porous microstructures of different types, inc

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Goel, Kishan Kumar, Ritu Sapra, and Purushottam Kumar Arya. "Mapping the ESG-corporate finance literature in India: systematic literature review, bibliometric analysis and future directions." Journal of Indian Business Research, May 26, 2025. https://doi.org/10.1108/jibr-06-2024-0152.

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Purpose Although past studies have reviewed the role of corporate social responsibility (CSR) and environmental, social and governance (ESG) factors in corporate finance, growing realization on the influence of contextual variables has necessitated re-examination in light of unique situational settings. Given that India presents a distinctive context, this study aims to map, synthesize and evaluate the Indian literature on corporate ESG and its role in financial management. Design/methodology/approach The study adopts a combination of qualitative and quantitative techniques. Using systematic p

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Ballis, Haris, and Loukas Dimitriou. "Exploitation of Aggregate Mobility Sensing Data for the Synthesis of Disaggregate Multimodal Tours in Megacities." Frontiers in Future Transportation 2 (April 30, 2021). http://dx.doi.org/10.3389/ffutr.2021.647852.

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The unprecedented volume of urban sensing data has allowed the tracking of individuals at remarkably high resolution. As an example, Telecommunication Service Providers (TSPs) cannot provide their service unless they continuously collect information regarding the location of their customers. In conjunction with appropriate post-processing methodologies, these traces can be augmented with additional dimensions such as the activity of the user or the transport mode used for the completion of journeys. However, justified privacy concerns have led to the enforcement of legal regulations aiming to

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Phung, Khoa, Emmanuel Ogunshile, and Mehmet E. Aydin. "Domain-specific implications of error-type metrics in risk-based software fault prediction." Software Quality Journal 33, no. 1 (2025). https://doi.org/10.1007/s11219-024-09704-1.

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AbstractIn software development, Software Fault Prediction (SFP) is essential for optimising resource allocation and improving testing efficiency. Traditional SFP methods typically use binary-class models, which can provide a limited perspective on the varying risk levels associated with individual software modules. This study explores the impacts of Error-type Metrics on the fault-proneness of software modules in domain-specific software projects. Also, it aims to enhance SFP methods by introducing a risk-based approach using Error-type Metrics. This method categorises software modules into H

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Sarzynski, Sadia H., Alexander Lawandi, Sarah Warner, et al. "Association between minimum inhibitory concentration values and mortality risk in patients with Stenotrophomonas maltophilia infections: a retrospective cohort study of electronic health records from 148 US hospitals." JAC-Antimicrobial Resistance 5, no. 2 (2023). http://dx.doi.org/10.1093/jacamr/dlad049.

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Abstract Background Clinical data informing antimicrobial susceptibility breakpoints for Stenotrophomonas maltophilia infections are lacking. We sought to leverage real-world data to identify MIC values within the currently defined susceptible range that could discriminate mortality risk for patients with S. maltophilia infections and guide future breakpoint revisions. Methods Inpatients with S. maltophilia infection who received single-agent targeted therapy with levofloxacin or trimethoprim/sulfamethoxazole were identified in the Cerner HealthFacts electronic health record database. Encounte

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Marts, Erika, Frederick P. Rivara, N. Jeanie Santaularia, and Ali Rowhani-Rahbar. "Adolescent firearm injury trends at a Level I trauma center in Washington State, USA, 2011–2021." BMC Pediatrics 25, no. 1 (2025). https://doi.org/10.1186/s12887-025-05816-0.

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Abstract Background Firearm-related harm is a pressing public health problem in the United States, particularly among adolescents. While informative, national level data may mask variations in firearm injury incidence across and within states.Publicly available firearm injury data may be limited or unavailable, highlighting the importance of analyzing more granular data to develop or refine tailored interventions shaped by the unique needs and contexts of individual communities. Methods This retrospective cohort study used data from a Level I Trauma Center and death records to examine adolesce

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