Relevant bibliographies by topics / Inhalant allergens

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Academic literature on the topic 'Inhalant allergens'

Author: Grafiati
Published: 4 June 2025
Last updated: 6 July 2025

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Journal articles on the topic "Inhalant allergens"

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Hongzhi, Gu, Deng Xiangfen, Zhang Jing, and Xiaoyan. "Analysis of skin prick test results for 224 patients with eczema." E3S Web of Conferences 185 (2020): 03004. http://dx.doi.org/10.1051/e3sconf/202018503004.

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Objective: To understand the common inhalant allergens and food allergens and their characteristics on patients with eczema in Chongqing area. Method: Skin prick tests of common inhalant allergens and food allergens were performed on 224 patients with eczema and the test results were analyzed. Results: Among the 224 patients with eczema, 137 reacted positively to one or more allergens, with a positive rate reaching 61.2%; the inhalant allergens that ranked top 3 in the positive rate were dermatophagoides pteronyssinus (41.1%), dermatophagoides farina (37.5%), cockroach (35.3%). The top three food allergens were shrimp (7.1%), milk (4.5%), egg (4%). Conclusions: Patients with eczema were allergic to one or more allergens, and the major inhalant allergens were dermatophagoides pteronyssinus, dermatophagoides farinae and cockroaches. The positive rate of food allergens was lower that the inhalant counterparts, and the difference between male and female was not statistically significant (P>0.05). Allergen prick tests could facilitate identifying the inhalant allergens and food allergens of patients with eczema, improve treatment and health education of patients with eczema, and provide a reliable basis for effective prevention and normalized treatment.
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Knyziak-Mędrzycka, Izabela, Bożena Cukrowska, Wojciech Nazar, et al. "Sensitization to Food and Aero-Allergens in Children with Coeliac Disease Assessed with the Use of a Multiplex Molecular Diagnostic Technique." Journal of Clinical Medicine 13, no. 10 (2024): 2992. http://dx.doi.org/10.3390/jcm13102992.

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(1) Background. Coeliac disease (CD) often co-occurs with autoimmune conditions or genetic syndromes, but there are few studies on the co-existence of CD and immunoglobulin E (IgE)-mediated allergies. The purpose of this study was to assess sensitization to food and aero-allergens in pediatric patients with CD. (2) Methods. A multiplex ALEX®2 test was used to determine specific IgEs (sIgEs). (3) Results. The study included 108 children newly diagnosed with CD. Allergen extract- and/or allergen molecule-sIgEs were detected in 49.1% of children. Most children (41.5%) were sensitized to both inhalant and food allergens. The three most common aero-allergens (timothy pollen, ryegrass, silver birch) were molecules Phl p 1, Lol p 1, and Bet v 1. The most common food allergens (hazelnut, apple, and peanut) were Cor a 1, Mal d 1, and Ara h 8 molecules of the PR-10 subfamily. Patients were not sensitized to cereal allergens containing gluten. Spearman’s rank correlation analysis of sensitized patients showed a significant positive relationship (r = 0.31) between the patients’ age and the occurrence of positive sIgEs (≥0.3 kUA/L) for inhalant allergen molecules (p = 0.045). In sensitized patients, mainly symptoms of inhalant allergy were observed, such as hay fever, conjunctivitis, and bronchial asthma. (4) Conclusions. The current study indicates the co-occurrence of IgE sensitization to food and inhalant allergens in children with CD. The study highlights the need to take a closer look at the diagnosis of IgE-mediated allergy in patients with CD, which may help in their care and lead to a better understanding of the relationship between CD and IgE-mediated allergy.
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Brand, Paul L. P., Richard M. Brohet, Olof Schwantje, and Lambert D. Dikkeschei. "Association between allergen component sensitisation and clinical allergic disease in children." Allergologia et Immunopathologia 50, no. 2 (2022): 131–41. http://dx.doi.org/10.15586/aei.v50i2.598.

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Background: Allergen component sensitisation testing is becoming increasingly important in the diagnosis of peanut allergy. The aim of the present study was to evaluate the relationship between sensitisation and symptoms of allergic disease in children by testing a large panel of inhalants, food allergens, and allergen components. Methods: For 287 children visiting our laboratory for allergy testing, symptoms of allergic disease were recorded by standardised validated questionnaires. Specific IgE to 11 whole allergens was assessed by ImmunoCAP, and to 112 allergen components by ISAC ImmunoCAP assay. We used latent class analysis (LCA) to distinguish clinical phenotypes. Results: Inhalant and food allergen sensitisation was common, irrespective of the children’s allergic symptom type. Less than 10% of the variance in symptom scores was explained by variations in the number of allergens (components) that the child was sensitised to. In LCA, 135 children (50.2%) had mild allergy, with few symptoms and sensitisation to no or few allergens, 74 children (27.5%) had more symptoms and sensitisation to inhalant allergens (respiratory allergy) and 60 children (22.3%) showed polysensitisation to a median of six allergens and had more severe symptoms of different organ systems. Adding allergen component test results to LCA failed to result in identifiable classes of allergic disease in children. Conclusions: In this group of children with allergic symptoms, referred for allergy testing by their physician, broad screening for allergen component sensitisation did not contribute to distinguishing phenotypes of allergic disease.
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Obaid, Dr/Jamil, and Dr/Waheed Ali. "Sensitization Pattern to common Inhalant allergens among patients with Allergic Rhinitis in Taiz, Yemen." مجلة جامعة السعيد للعلوم الانسانية و التطبيقية 3, no. 2 (2019): 9. http://dx.doi.org/10.59325/sjhas.v3i2.69.

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Introduction: Allergic rhinitis (AR) affects millions of people annually and is associated with significant morbidity resulting in substantial health care costs to society. Inhalant allergens as one of the most common cause of allergic disease derived from pollens, dust mites, fungi, and animals. The prevalence of inhalant allergens is different in various areas. Objectives: This study was designed to identify the frequency of sensitization to aeroallergens in patients with AR in Taiz, Yemen. Materials and Methods: This cross-sectional study was conducted in Taiz, Yemen between March 2014 and October 2017. Patients with symptoms suggesting AR and have elevated total immunoglobulin-E (IgE) and sensitized to at least one inhalant allergen are included in this study. The severity of AR was assessed using special scoring system. Sensitization to inhalant allergens was assessed by skin prick test using a panel of common 12 inhalant allergens. Results: Sex ratio being 1.66:1, male: female. Age distribution ranged from 11 years to 67 years. House dust mite were the most common type of inhalant allergens (44.76%), followed by Cockroach (16.67%), house dust (14.76%), Mesquite (12.38%) and cat hair (10.45%). Conclusion: The results of the present study revealed that HDMs play as a main sensitizing allergen in allergic rhinitis. This pattern was compatible with the results from studies carried in other areas with the same climate.
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Marinovic, María Angélica. "ENVIRONMENTAL ALLERGENS AND ASTHMA." Neumología Pediátrica 18, no. 4 (2023): 108–11. http://dx.doi.org/10.51451/1zqrvz35.

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Exposure to inhalant allergens is associated with allergen-specific sensitization, a risk factor for the development of bronchial asthma, along with genetic and environmental factors. Early life exposure to mites increases the risk of sensitization and development of asthma in high-risk children. The same would occur with cat allergen levels inside the house and increased risk of sensitization in preschool and school. On the other hand, early contact with multiple microorganisms contributes to preventive immunomodulation by inducing tolerance to allergens. Climate change has been shown to increase the potency of allergenic pollens and the severity of exposure to fungi, which could partly explain the increase in allergic diseases in recent years. There is much evidence regarding exposure to allergens in sensitized asthmatic children and asthma exacerbation. It is essential to know which allergens the patient is sensitized to in order to implement environmental avoidance measures. This article summarizes an update on the mechanisms of sensitization to inhalant allergens in asthmatic children and its relationship with climate change and asthma severity. The main prevention measures, environmental control and the role of immunotherapy are also presented.
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Al-Mughales, Jamil A. "Diagnostic Utility of Total IgE in Foods, Inhalant, and Multiple Allergies in Saudi Arabia." Journal of Immunology Research 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/1058632.

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Objective.To assess the diagnostic significance of total IgE in foods, inhalant, and multiple allergies.Methods.Retrospective review of the laboratory records of patients who presented with clinical suspicion of food or inhalant allergy between January 2013 and December 2014. Total IgE level was defined as positive for a value >195 kU/L; and diagnosis was confirmed by the detection of specific IgE (golden standard) for at least one food or inhalant allergen and at least two allergens in multiple allergies.Results.A total of 1893 (male ratio = 0.68, mean age = 39.0 ± 19.2 years) patients were included. Total IgE had comparable sensitivity (55.8% versus 59.6%) and specificity (83.9% versus 84.4%) in food versus inhalant allergy, respectively, but a superior PPV in inhalant allergy (79.1% versus 54.4%). ROC curve analysis showed a better diagnostic value in inhalant allergies (AUC = 0.817 (95% CI = 0.796–0.837) versus 0.770 (95% CI = 0.707–0.833)). In multiple allergies, total IgE had a relatively good sensitivity (78.6%), while negative IgE testing (<195 kU/L) predicted the absence of multiple allergies with 91.5% certitude.Conclusion.Total IgE assay is not efficient as a diagnostic test for foods, inhalant, or multiple allergies. The best strategy should refer to specific IgE testing guided by a comprehensive atopic history.
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Otsuka, Hirokuni, Kuninori Otsuka, Shoji Matsune, and Kimihiro Okubo. "Assessing the Onset of Allergic Rhinitis by Nasal Cytology and Immunoglobulin E Antibody Levels in Children." American Journal of Rhinology & Allergy 32, no. 1 (2018): 16–22. http://dx.doi.org/10.2500/ajra.2018.32.4503.

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Background It is difficult to identify the onset of allergic rhinitis in infants because making a conclusive diagnosis can be challenging. Objective We used a combination of cell differentials in nasal swabs and immunoglobulin E (sIgE) antibody values to food and inhalant allergens to make the diagnosis and identify relevant allergens for investigation of the onset of allergic rhinitis. Methods We studied 302 children, 2 to 120 months old, who visited our clinic for rhinorrhea. Nasal swabs were taken from all children, and neutrophils (N), eosinophils (Eo), and mast cells (Mc) were identified by nasal cytology and their numbers were estimated. Levels of sIgE antibodies to various food and inhalant allergens were determined in patients with nasal Eo and Mc. Results Percentages of participants with Eo-Mc and Eo-Mc-N at 2–14 (n = 84), 15–24 (n = 57), 25–60 (n = 73), and 61–120 months of age (n = 88) were 20, 23, 58, and 65%, respectively. There were no significant differences between the 2–14 and 15–24, and 25–60 and 61–120 months age groups, but there was a significant difference between the 15–24 and 25–60 months age groups (p = 0.00013). The percentages of participants with sIgE antibodies to food and inhalant allergens as solitary or main allergen were 12%/0% at 2–14 months old, 10.5%/7% at 15–24 months old, 1.3%/42.4% at 25–60 months old, and 0%/56.8% at 61–120 months old, respectively with a significant difference between 15–24 and 25–60 months old groups (p = 0.00025) for inhalant allergens. Conclusion Allergic rhinitis associated with inhalant allergens in infants <15 months of age is rare, but it is tempting to postulate that symptoms of rhinitis in these infants may be associated with sIgE antibodies to food allergens. Transition of sIgE responses from food to inhalant allergens occurred after 15 months of age, and sIgE antibodies to inhalant allergens were predominant after 25 months.
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Petersen, Arnd, Wolf Becker, and Uta Jappe. "What makes peanuts so allergenic?" Journal of the Serbian Chemical Society 78, no. 3 (2013): 321–31. http://dx.doi.org/10.2298/jsc121105007p.

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Peanut allergy belongs to one of the most severe food allergies. So far 12 peanut allergens have been registered by the IUIS Allergen Nomenclature Subcommittee. Here, we describe the different peanut allergens and factors that contribute to allergenicity. Peanut contains several class I food allergens (especially Ara h 1, 2, 3) that are stable against heat denaturation and proteolytic digestion and represent storage proteins. These allergens are often associated with severe allergic reactions. Additionally, peanut contains class II food allergens (Ara h 5 and 8), where the IgE reactivity is caused by cross reactions to inhalant allergens. These allergens are mostly associated with mild to moderate allergic reactions. But the severity of symptoms may change by involvement of additional factors. The peanut matrix consists of about 50% of lipids, and allergen - lipid associations have been shown for several peanut allergens. Further factors influencing allergenicity depend on peanut varieties, geographical differences and alterations in food processing. Finally, the physiological function of allergens and the mechanisms, by which they interact with the immune system, are further modulating factors. Thus, the specific allergen structure, matrix, genetic variations, geographic alterations and further augmentation factors are important parameters that induce and influence allergenicity.
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Jeong, Kyoung Yong, and Jung-Won Park. "Insect Allergens on the Dining Table." Current Protein & Peptide Science 21, no. 2 (2020): 159–69. http://dx.doi.org/10.2174/1389203720666190715091951.

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Edible insects are important sources of nutrition, particularly in Africa, Asia, and Latin America. Recently, edible insects have gained considerable interest as a possible solution to global exhaustion of the food supply with population growth. However, little attention has been given to the adverse reactions caused by insect consumption. Here, we provide an overview of the food allergens in edible insects and offer insights for further studies. Most of the edible insect allergens identified to date are highly cross-reactive invertebrate pan-allergens such as tropomyosin and arginine kinase. Allergic reactions to these allergens may be cross-reactions resulting from sensitization to shellfish and/or house dust mites. No unique insect allergen specifically eliciting a food allergy has been described. Many of the edible insect allergens described thus far have counterpart allergens in cockroaches, which are an important cause of respiratory allergies, but it is questionable whether inhalant allergens can cause food allergies. Greater effort is needed to characterize the allergens that are unique to edible insects so that safe edible insects can be developed. The changes in insect proteins upon food processing or cooking should also be examined to enhance our understanding of edible insect food allergies.
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van Ree, R. "Clinical importance of non-specific lipid transfer proteins as food allergens." Biochemical Society Transactions 30, no. 6 (2002): 910–13. http://dx.doi.org/10.1042/bst0300910.

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Non-specific lipid transfer proteins (nsLTPs) have recently been identified as plant food allergens. They are good examples of true food allergens, in the sense that they are capable of sensitizing, i.e. inducing specific IgE, as well as of eliciting severe symptoms. This is in contrast with most plant food allergens, which are recognized because of primary sensitization to related inhalant allergens (cross-reactivity), i.e. pollen allergens. The basis of the difference between the latter category and strong food allergens such as nsLTPs appears to lie in the sensitivity of the allergens to proteolytic attack and food processing. Stability allows the allergen to reach the gastrointestinal immune system in an immunogenic and allergenic conformation, allowing sensitization and induction of systemic symptoms. Stability also explains the presence of such allergens in processed foods. Together, these characteristics make nsLTPs clinically highly relevant plant food allergens and ideal tools with which to study the mechanisms involved in food allergy.
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Book chapters on the topic "Inhalant allergens"

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Pomés, Anna, and Coby Schal. "Cockroach and other inhalant insect allergens." In Allergens and Allergen Immunotherapy. CRC Press, 2020. http://dx.doi.org/10.1201/9781351208994-15.

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Nelson, Harold S. "Allergy Immunotherapy for Inhalant Allergens." In Textbook of Diagnostic and Therapeutic Procedures in Allergy. CRC Press, 2024. http://dx.doi.org/10.1201/9781003269427-17.

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Park, Jung-Won. "Food, Inhalant, and Microbial Allergens." In Practical Insights into Atopic Dermatitis. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-8159-5_10.

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Platts-Mills, T. A. E., M. D. Chapman, B. Mitchell, P. W. Heymann, and B. Deuell. "Role of Inhalant Allergens in Atopic Eczema." In Handbook of Atopic Eczema. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-662-02671-7_21.

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Jeebhay, Mohamed F., and Berit Bang. "Occupational Allergy and Asthma Associated with Inhalant Food Allergens." In Food Allergy. CRC Press, 2017. http://dx.doi.org/10.1201/9781315120126-8.

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Mitchell, E. B. "Delayed-type Hypersensitivity Responses to Inhalant Allergens: a Form of Cutaneous Basophil Hypersensitivity (CBH)." In Highlights in Asthmology. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-70316-4_16.

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Chang, Christopher, Patrick S. C. Leung, Saurabh Todi, and Lori Zadoorian. "Definition of Allergens: Inhalants, Food, and Insects Allergens." In Allergy and Asthma. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-58726-4_3-1.

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Chang, Christopher, Patrick S. C. Leung, Saurabh Todi, and Lori Zadoorian. "Definition of Allergens: Inhalants, Food, and Insects Allergens." In Allergy and Asthma. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-05147-1_3.

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Jacobs, Joela. "Pollen." In Microbium. punctum books, 2023. http://dx.doi.org/10.53288/0396.1.08.

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When you are inhaling pollen, your body has been penetrated by a little package of plant sperm. Pollen grains are multicellular organisms that contain male sex cells, and their job is to get this sperm to the egg to facilitate fertilization. For that, they hitch a ride on insects or trust their fate to wind, water, and any other moving means, including us. Yet most human-pollen encounters are only noticed when they result in an allergic reaction. Allergies have been on the rise, which is at least partly because pollen is too: Pollen counts have been going up in urban environments due to the tendency of city planners to plant male trees, which avoids problems with fruit falling on heads, cars, and sidewalks. Yet this also means that pollen is not absorbed by female trees and left roaming the streets to enter human noses instead. This self-made allergy problem demonstrates that we often seem to neglect what pollen is and does: As a miniscule sperm delivery mechanism, it is all about sex. Accordingly, pollen’s cultural history has predominantly been focused on attraction rather than allergic aversion, and because of that, pollen has shaped not only our understanding of plant fertility, but also human ideas about eroticism and sexuality, reproduction and desire.
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"Cockroach and Other Inhalant Insect Allergens." In Allergens and Allergen Immunotherapy. CRC Press, 2004. http://dx.doi.org/10.1201/b14399-18.

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Conference papers on the topic "Inhalant allergens"

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Luzak, Agnes, Claudia Flexeder, Andrea Von Berg, et al. "Relation of inhalant allergen-specific immunoglobulin E and lung function in adolescents." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa3388.

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Kim, Jinho, and Jim S. Chen. "Effect of Inhaling Patterns on Aerosol Drug Delivery: CFD Simulation." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-66685.

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Inhaled Pharmaceutical Aerosols (IPAs) delivery has great potential in treatment of a variety of respiratory diseases, including asthma, pulmonary diseases, and allergies. Aerosol delivery has many advantages. It delivers medication directly to where it is needed and it is effective in much lower doses than required for oral administration. Currently, there are several types of IPA delivery systems, including pressurized metered dose inhaler (pMDI), the dry powder inhaler (DPI), and the medical nebulizer. IPAs should be delivered deep into the respiratory system where the drug substance can be absorbed into blood through the capillaries via the alveoli. Researchers have proved that most aerosol particles with aerodynamic diameter of about 1–5 μm, if slowly and deeply inhaled, could be deposited in the peripheral regions that are rich in alveoli [1–3]. The purpose of this study is to investigate the effects of various inhaling rates with breath-holding pause on the aerosol deposition (Dp = 0.5–5 μm) in a human upper airway model extending from mouth to 3rd generation of trachea. The oral airway model is three dimensional and non-planar configurations. The dimensions of the model are adapted from a human cast. The air flow is assumed to be unsteady, laminar, and incompressible. The investigation is carried out by Computational Fluid Dynamics (CFD) using the software Fluent 6.2. The user-defined function (UDF) is employed to simulate the cyclic inspiratory flows for different IPA inhalation patterns. When an aerosol particle enters the mouth respiratory tract, its particles experience abrupt changes in direction. The secondary flow changes its direction as the airflow passes curvature. Intensity of the secondary flow is strong after first bend at pharynx and becomes weaker after larynx. In flow separation, a particle can be trapped and follow the eddy and deposit on the surface. Particle deposition fraction generally increases as particle size and inhaling airflow velocity increase.
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