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Dissertations / Theses on the topic 'Inhibitory Neurons'

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1

Husson, Zoé. "Glycinergic neurons and inhibitory transmission in the cerebellar nuclei." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066279/document.

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Le cervelet, composé d'un cortex et de noyaux, est responsable du contrôle moteur fin des mouvements et de la posture. En combinant une approche génétique (basée sur l'utilisation de lignées de souris transgéniques) avec des traçages anatomiques, des marquages immunohistochimiques et des expériences d'électrophysiologie et d'optogénétique, nous établissons les caractères distinctifs des neurones inhibiteurs des noyaux cérébelleux et en détaillons la connectivité ainsi que les fonctions dans le circuit cérébelleux. Les neurones inhibiteurs glycinergiques des noyaux profonds constituent une popu
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2

Li, Yan. "Inhibitory synpatic transmission in striatal neurons after transient cerebral ischemia." Connect to resource online, 2009. http://hdl.handle.net/1805/2021.

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Thesis (Ph.D.)--Indiana University, 2009.<br>Title from screen (viewed on December 1, 2009). Department of Anatomy and Cell Biology, Indiana University-Purdue University Indianapolis (IUPUI). Advisor(s): Zao C. Xu, Feng C. Zhou, Charles R. Yang, Theodore R. Cummins. Includes vitae. Includes bibliographical references (leaves 115-135).
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3

Bampasakis, Dimitris. "Inhibitory synaptic plasticity and gain modulation in cerebellar nucleus neurons." Thesis, University of Hertfordshire, 2016. http://hdl.handle.net/2299/17179.

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Neurons can encode information using the rate of their action potentials, making the relation between input rate and output rate a prominent feature of neuronal information processing. This relation, known as I{O function, can rapidly change in response to various factors or neuronal processes. Most noticeably, a neuron can undergo a multiplicative operation, resulting in a change of the slope of its I{O curve, also know as gain change. Gain changes represent multiplicative operations, and they are wide- spread. They have been found to play an important role in the encoding of spatial location
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4

Wang, Hui. "Structural and functional studies of the neuronal growth inhibitory factor, human metallothionein-3." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/HKUTO/record/B39559014.

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5

Wang, Hui, and 王暉. "Structural and functional studies of the neuronal growth inhibitory factor, human metallothionein-3." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B39559014.

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6

Mardinly, Alan Robert. "Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:10739.

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Neuronal activity and subsequent calcium influx activates a signaling cascade that causes transcription factors in the nucleus to rapidly induce an early-response program of gene expression. This early-response program is composed of transcriptional regulators that in turn induce transcription of late-response genes, which are enriched for regulators of synaptic development and plasticity that act locally at the synapse.
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7

Chik, Tai-wai David. "Global coherent activities in inhibitory neural systems Chik Tai Wai David." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31040408.

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8

Lofredi, Roxanne [Verfasser]. "Characterization of inhibitory and projection specific neurons of the presubiculum / Roxanne Lofredi." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2017. http://d-nb.info/1126505005/34.

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9

Pangalos, Maria. "Analysis of hippocampal inhibitory and excitatory neurons during sharp wave-associated ripple." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2016. http://dx.doi.org/10.18452/17590.

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Im Hippokampus gibt es verschiedene Netzwerkoszillationen mit unterschiedlichen Frequenzen. Ein Typ dieser Oszillationen sind die ”Ripple” mit einer Frequenz von etwa 200 Hz, welche in Komplexen mit einer Aktivitätswelle, der ”Sharp wave” auftreten. Sharp wave-ripple Komplexe (SWR) werden mit der Konsolidierung von Gedächtnis in Zusammenhang gebracht. Das Netzwerk, das den SWR unterliegt, hat bestimmte Mechanismen, von denen einige in der vorliegenden Arbeit näher untersucht werden. Im ersten Teil wird untersucht, wie ein hemmendes Interneuron in der hippokampalen Region CA1, das ”oriens-lacu
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10

Chik, Tai-wai David, and 戚大衛. "Global coherent activities in inhibitory neural systems: Chik Tai Wai David." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31040408.

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11

Dobie, Frederick Andrew. "Molecular and cellular mechanisms of inhibitory synapse formation in developing rat hippocampal neurons." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/41933.

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The proper functioning of the brain and central nervous system (CNS) requires the precise formation of synapses between neurons. The two main neurotransmitter systems for fast synaptic communication in the CNS are excitatory glutamate and inhibitory gamma-aminobutyric acid. A growing body of evidence has begun to uncover several shared and divergent rules for the establishment of each of these two types of synapses. At the molecular level, a number of key proteins have been shown to be involved in the initial formation and subsequent development of synaptic connection, including cell adhesion
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12

Scheimann, Jessie R. "Sex Differences in the Role of Glucocorticoid Receptors in Excitatory vs Inhibitory Neurons." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1554213356486937.

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13

Blurton-Jones, Mathew Mark. "Estrogen modulates neurotrophin systems in the brain via putative actions on inhibitory neurons /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2002. http://wwwlib.umi.com/cr/ucsd/fullcit?p3064473.

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14

Backström, Eva. "Expression of stimulatory and inhibitory molecules in interactions between natural killer cells and neurons /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-516-6.

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15

Doolin, Richard Edward. "An odorant-suppressible chloride conductance mediates inhibitory receptor potentials in lobster olfactory receptor neurons." [Gainesville, Fla.] : University of Florida, 2002. http://purl.fcla.edu/fcla/etd/UFE1001136.

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16

Austin, Mason. "Is the lateral septum's inhibitory influence on the amygdala mediated by GABA-ergic neurons?" Diss., Connect to the thesis, 2004. http://hdl.handle.net/10066/741.

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17

Jalil, Sajiya Jesmin. "Stability Analysis of Phase-Locked Bursting in Inhibitory Neuron Networks." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/math_diss/7.

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Networks of neurons, which form central pattern generators (CPGs), are important for controlling animal behaviors. Of special interest are configurations or CPG motifs composed of reciprocally inhibited neurons, such as half-center oscillators (HCOs). Bursting rhythms of HCOs are shown to include stable synchrony or in-phase bursting. This in-phase bursting can co-exist with anti-phase bursting, commonly expected as the single stable state in HCOs that are connected with fast non-delayed synapses. The finding contrasts with the classical view that reciprocal inhibition has to be slow or time-d
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18

Ng, Yu Pong. "Leukemia inhibitory factor receptor signaling in NGF-induced neuronal differentiation of PC12 cells /." View abstract or full-text, 2004. http://library.ust.hk/cgi/db/thesis.pl?BICH%202004%20NG.

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Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2004.<br>Includes bibliographical references (leaves 134-172). Also available in electronic version. Access restricted to campus users.
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19

Chéry, Nadège. "Inhibitory control of neurons in the marginal zone (lamina I) of the rat spinal cord." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0032/NQ64534.pdf.

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20

McDougal, Robert A. "Excitatory-Inhibitory Interactions as the Basis of Working Memory." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1313004219.

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21

Beebe, Nichole L. "Perineuronal nets and the inhibitory circuitry of the auditory midbrain: evidence for subtypes of GABAergic neurons." Kent State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=kent1468938365.

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22

Layne, Robert Michael. "The AIB interneurons are modulated by excitatory and inhibitory signaling pathways to shape aversive behaviors in response to 1-octanol." University of Toledo / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1445452178.

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23

Guilbert, Erin. "Inhibitory role of d-series resolvins in the cellular response to painful stimuli in trigeminal ganglion neurons." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12405.

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Thesis (M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Resolvins (Rv) are molecules that are responsible for the active resolution of inflammation. Recent studies have suggested that the resolvins are capable of inhibiting pain associated with inflammation. Our goal
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24

Kaplan, Eitan S. "Visual cortical plasticity : the role of parvalbumin expressing inhibitory neurons and abnormalities in models of neurodevelopmental disorders." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/103210.

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Thesis: Ph. D. in Neuroscience, Massachusetts Institute of Technology, Department of Brain and Cognitive Sciences, 2016.<br>Cataloged from PDF version of thesis. Vita.<br>Includes bibliographical references (pages 121-134).<br>The roles played by cortical inhibitory neurons in experience-dependent plasticity and learning are not well understood. Here we evaluate the participation of parvalbumin-expressing (PV+) GABAergic neurons in two forms of experience-dependent modification of primary visual cortex (V1) in adult mice: ocular dominance (OD) plasticity resulting from monocular deprivation an
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25

Baca, Serapio Michael. "Inhibitory motor neurons are essential for the production of local bending in the medicinal leech (Hirudo medicinalis) /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2005. http://wwwlib.umi.com/cr/ucsd/fullcit?p3167858.

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26

Bihun, Marzena Maria. "Functional relevance of inhibitory and disinhibitory circuits in signal propagation in recurrent neuronal networks." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31148.

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Cell assemblies are considered to be physiological as well as functional units in the brain. A repetitive and stereotypical sequential activation of many neurons was observed, but the mechanisms underlying it are not well understood. Feedforward networks, such as synfire chains, with the pools of excitatory neurons unidirectionally connected and facilitating signal transmission in a cascade-like fashion were proposed to model such sequential activity. When embedded in a recurrent network, these were shown to destabilise the whole network’s activity, challenging the suitability of the model. He
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27

Ure, Daren Raymond. "Retrograde signaling and retrograde axonal transport of leukemia inhibitory factor and nerve growth factor by cultured sympathetic neurons." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq21648.pdf.

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28

Fujiyama, Tomoyuki. "Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1." Kyoto University, 2012. http://hdl.handle.net/2433/157456.

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29

Miyazaki, Yoshiya. "Xenon Has Greater Inhibitory Effects on Spinal Dorsal Horn Neurons than Nitrous Oxide in Spinal Cord Transected Cats." Kyoto University, 2000. http://hdl.handle.net/2433/181269.

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30

Whittaker, Maximilian Anthony Erik. "Modulation of fast-spiking interneurons using two-pore channel blockers." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31252.

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The balance between excitatory and inhibitory synaptic transmission within and across neurons in active networks is crucial for cortical function and may allow for rapid transitions between stable network states. GABAergic interneurons mediate the majority of inhibitory transmission in the cortex, and therefore contribute to the global balance of activity in neuronal networks. Disruption in the network balance due to impaired inhibition has been implicated in several neuropsychiatric diseases (Marin 2012). Both schizophrenia and autism are two highly heritable cognitive disorders with complex
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31

Cleland, Thomas A. "Inhibitory glutamate receptor channels : characterization and modulation in cultured lobster stomatogastric neurons : or it's amazing it works at all /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1997. http://wwwlib.umi.com/cr/ucsd/fullcit?p9724889.

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32

Delgado, Arriagada Ricardo Alfonso [Verfasser]. "Molecular components involved in the inhibitory responses and Ca2+ clearance from the cilia of olfactory receptor neurons / Ricardo Alfonso Delgado Arriagada." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover (TIB), 2011. http://d-nb.info/1019723386/34.

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33

Pangalos, Maria [Verfasser], Richard [Gutachter] Kempter, Dietmar [Gutachter] Schmitz, and Nikolai [Gutachter] Axmacher. "Analysis of hippocampal inhibitory and excitatory neurons during sharp wave-associated ripple / Maria Pangalos ; Gutachter: Richard Kempter, Dietmar Schmitz, Nikolai Axmacher." Berlin : Lebenswissenschaftliche Fakultät, 2016. http://d-nb.info/1113686162/34.

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34

Avigdor, Mauricio. "Natural Neuronal Variation in a Complex Neuroendocrine Pathway: Effect of Selection for Photoperiod Responsiveness on the Density and Location of Mature GNRH-Releasing Neurons in Inhibitory and Excitatory Photoperiods." W&M ScholarWorks, 2004. https://scholarworks.wm.edu/etd/1539626458.

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35

Painter, Palak Rajeshkumar. "Quantitative analysis of glycinergic neurons including Ia inhibitory interneurons in the ventral spinal cord using a BAC-GlyT2-eGFP transgenic mouse model." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1347911464.

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36

Bredack, Christoph [Verfasser], Sonja [Akademischer Betreuer] Wojcik, Erwin [Akademischer Betreuer] Neher, and Ahmed [Akademischer Betreuer] Mansouri. "Genetic Targeting and Analysis of Parvalbumin and VGLUT3 Expressing Inhibitory Neurons / Christoph Bredack. Gutachter: Sonja Wojcik ; Erwin Neher ; Ahmed Mansouri. Betreuer: Sonja Wojcik." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2012. http://d-nb.info/1042305536/34.

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37

Marx, Manuel [Verfasser]. "Intralaminar and translaminar microcircuits involving excitatory and inhibitory neurons in layer 6B of the somatosensory rat barrel cortex : a morphological, physiological and immunofluorescence study / Manuel Marx." Aachen : Hochschulbibliothek der Rheinisch-Westfälischen Technischen Hochschule Aachen, 2014. http://d-nb.info/1051528771/34.

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38

Duguid, Ian Charles. "Inhibitory synaptic plasticity in the cerebellum." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368689.

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39

Nakamizo, Tomoki. "Phosphodiesterase inhibitors are neuroprotective to cultured spinal motor neurons." Kyoto University, 2003. http://hdl.handle.net/2433/148692.

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40

Chow, Wei-Yan. "Inhibitory neuron lamination in the developing zebrafish retina." Thesis, University of Cambridge, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708976.

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41

Upton, Laura. "Altered prefrontal circuit assembly and function in mice lacking the glycine receptor α2 subunit, a model of autism and intellectual disability". Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS714.

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Des variants pathogènes du gène GLRA2 codant pour la sous-unité α2 du récepteur glycinergique ont été récemment impliqués dans le trouble du spectre autistique (TSA) et la déficience intellectuelle. Notre groupe a précédemment montré que les souris mâles déficientes en Glra2 (Glra2–/Y) présentent un déficit de mémoire lors du test de reconnaissance d’objets (TRO) et une altération de la plasticité synaptique du cortex préfrontal (CPF), une région fortement impliquée dans le TSA. Par ailleurs, des études développementales des souris Glra2–/Y ont décrit un défaut de migration des interneurones e
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42

Tarczy-Hornoch, Kristina. "Physiology of synaptic inputs to layer IV of cat visual cortex." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337608.

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43

De, Sousa Sara Luisa Mellor. "Effects of the general anaesthetics isoflurane and xenon on synaptic transmission in isolated hippocampal neurones." Thesis, Imperial College London, 1999. http://hdl.handle.net/10044/1/8593.

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44

Landucci, Elisa. "Modeling Rett syndrome with iPSCs-derived neurons." Doctoral thesis, Università di Siena, 2018. http://hdl.handle.net/11365/1051069.

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Rett syndrome is a severe neurodevelopmental disorder. The condition affects approximately one in every 10.000 females and is only rarely seen in males. Causative mutations in the transcriptional regulator MeCP2 have been identified in more than 95% of classic Rett patients; mutations in CDKL5 are responsible for the early onset seizures Rett variant and mutations in FOXG1 gene lead to the congenital Rett variant. To shed light on molecular mechanisms underlying Rett syndrome onset and progression in disease-relevant cells, we took advantage of the breakthrough genetic reprogramming technology
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45

Jalics, Jozsi Z. "EXISTENCE OF SLOW WAVES IN MUTUALLY INHIBITORY THALAMIC NEURONAL NETWORKS." The Ohio State University, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=osu1023324103.

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46

Zeki, Mustafa. "DISCRETE ANALYSIS OF SYNCHRONIZED OSCILLATIONS IN EXCITATORY-INHIBITORY NEURONAL NETWORKS." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1282065976.

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47

Chan, Yuen-man, and 陳婉文. "Effect of caspase inhibitors on the survival and regeneration of injured spinal motoneurons." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31242893.

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48

Ngo, Dung. "Elucidating the Cellular and Molecular Changes of Dopaminergic Neurons by Rotenone-Induced Neurodegeneration in Zebrafish." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37921.

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Chemical-induced models have revealed the crucial role of oxidative stress and mito-chondrial dysfunction in the development of Parkinson’s Disease. In this project, firstly, we in-vestigated the mechanism of action of rotenone, a commercialized pesticide that was previously described to reproduce the bradykinetic dopaminergic neurodegeneration symptoms of Parkin-son’s Disease in zebrafish by inhibition of the mitochondrial complex I. We found out that rote-none caused change in the morphology of the zebrafish dopaminergic mitochondrial network. We also observed the altered expression of vari
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49

Yaraghi, Zahra. "The Neuronal Apoptosis Inhibitory Protein, NAIP, analysis of human and murine genetics." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0021/NQ46555.pdf.

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50

Jordan, Russell S. (Russell Stall). "Investigation of Inhibitory Influences in Neuronal Monolayer Networks Cultured from Mouse Spinal Cord." Thesis, University of North Texas, 1992. https://digital.library.unt.edu/ark:/67531/metadc500431/.

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The effects of the inhibitory neurotransmitters gammaamino butyric acid (GABA) and glycine were characterized on spontaneous activity recorded from mouse spinal cord cultures. The GABA concentration which completely inhibited burst activity was chosen as a quantifiable measure of culture drug response and was used to 1) assess interculture and intraculture variability, 2) determine the influence of culture age and initial activity on GABA responses, and 3) compare the GABA responses between networks obtained from whole spinal cord and ventral half spinal cord. Results showed that 1) no signifi
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