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1

Endo, Masayuki, Taisuke Jo, Takaaki Konishi, Ryosuke Kumazawa, Hiroki Matsui, and Hideo Yasunaga. "Association between Legionella Urinary Antigen Tests on Admission and Inhospital Mortality in Patients with Atypical Pneumonia: A Nationwide Database Study." International Journal of Mycobacteriology 12, no. 3 (2023): 350–56. https://doi.org/10.4103/ijmy.ijmy_135_23.

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Abstract Background: The guidelines for the requirement of Legionella urinary antigen tests on admission for patients hospitalized with community-acquired pneumonia differ in Japan, the United States, and Europe. We aimed to evaluate the association between the timing of Legionella urinary antigen testing and inhospital mortality in patients with atypical pneumonia. Methods: We identified 654,708 patients with atypical pneumonia from July 2010 to March 2021 using the Japanese national inpatient database. The patients were divided into groups that underwent Legionella urinary antigen tests on t
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Bazylev, V. V., A. B. Voevodin, V. A. Karnakhin, A. A. Martynov, and N. V. Zhukov. "Immediate outcomes of AVNeo in combination with coronary artery bypass grafting." Russian Journal of Cardiology 29, no. 12 (2024): 5832. https://doi.org/10.15829/1560-4071-2024-5832.

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Aim. To evaluate immediate outcomes of the Ozaki procedure in patients with coronary artery bypass grafting (CABG).Material and methods. This retrospective study included 416 patients operated on at the Federal Center of Cardiovascular Surgery (Penza). The patients were divided into two groups. The first group included 139 patients who underwent the AVNeo procedure in combination with CABG. The second group included 277 patients who underwent a single AVNeo procedure.Results. The median time of cardiopulmonary bypass and myocardial ischemia in the AVNeo+CABG group was 146 (134-165) and 115 (10
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You, Shoujiang, Xin Sun, Yi Zhou, et al. "The Prognostic Significance of White Blood Cell and Platelet Count for Inhospital Mortality and Pneumonia in Acute Ischemic Stroke." Current Neurovascular Research 18, no. 4 (2021): 427–34. http://dx.doi.org/10.2174/1567202618666211118141803.

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Background: We investigated the combined effect of white blood cell (WBC) and platelet count on in-hospital mortality and pneumonia in acute ischemic stroke (AIS) patients. Methods: A total of 3,265 AIS patients enrolled from December 2013 to May 2014 across 22 hospitals in Suzhou city were included in the present study. We divided patients into four groups according to their level of WBC and platelet count: LWHP (low WBC and high platelet), LWLP (low WBC and low platelet), HWHP (high WBC and high platelet), and HWLP (high WBC and low platelet). A logistic regression model was used to estimate
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Ozkarafakili, Müfide Arzu, Adem Melekoğlu, and Ertuğrul Altinbilek. "Clinical Evaluation of Chronic Obstructive Pulmonary Disease Patients Hospitalized with COVID-19 Pneumonia." Indian Journal of Respiratory Care 12, no. 01 (2023): 23–29. http://dx.doi.org/10.5005/jp-journals-11010-1006.

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Background: Coronavirus disease 2019 (COVID-19) has been a challenging viral respiratory tract infection since 2019 and may contribute to higher mortality in patients with chronic obstructive pulmonary disease (COPD). Methods: We analyzed the clinical data of 98 patients hospitalized with a diagnosis of COVID-19 and who had a previous diagnosis of COPD. They are grouped regarding GOLD ABCD stages, reported as follows whether in pandemic wards or intensive care units (ICU). The clinical outcomes were noted as a live hospital discharge or inhospital mortality. Results: A total of 76 patients (77
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Sicras-Mainar, Antoni, Jordi Ibáñez-Nolla, Isabel Cifuentes, Pablo Guijarro, Ruth Navarro-Artieda, and Lorenzo Aguilar. "Retrospective epidemiological study for the characterization of community- acquired pneumonia and pneumococcal pneumonia in adults in a well-defined area of Badalona (Barcelona, Spain)." BMC Infectious Diseases 12 (November 1, 2012): 283. https://doi.org/10.1186/1471-2334-12-283.

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Background Community-acquired pneumonia (CAP) has large impact on direct healthcare costs, especially those derived from hospitalization. This study determines impact, clinical characteristics, outcome and economic consequences of CAP in the adult (&ge;18 years) population attended in 6 primary-care centers and 2 hospitals in Badalona (Spain) over a two-year period. Methods Medical records were identified by codes from the International Classification of Diseases in databases (January 1<sup>st</sup>&nbsp;2008-December 31<sup>st</sup>&nbsp;2009). Results A total of 581 patients with CAP (55.6%
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Driscoll, Andrea, Maria J. Grant, Diane Carroll, et al. "The effect of nurse-to-patient ratios on nurse-sensitive patient outcomes in acute specialist units: a systematic review and meta-analysis." European Journal of Cardiovascular Nursing 17, no. 1 (2017): 6–22. http://dx.doi.org/10.1177/1474515117721561.

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Background: Nurses are pivotal in the provision of high quality care in acute hospitals. However, the optimal dosing of the number of nurses caring for patients remains elusive. In light of this, an updated review of the evidence on the effect of nurse staffing levels on patient outcomes is required. Aim: To undertake a systematic review and meta-analysis examining the association between nurse staffing levels and nurse-sensitive patient outcomes in acute specialist units. Methods: Nine electronic databases were searched for English articles published between 2006 and 2017. The primary outcome
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Arutyunov, G. P., E. I. Tarlovskaya, A. G. Arutyunov, et al. "Impact of vaccination status on the clinical course and outcomes of acute COVID-19 period: data from the international registry "Dynamics Analysis of Comorbidities in SARS-CoV-2 Survivors" (AKTIV-4)." Russian Journal of Cardiology 30, no. 3 (2025): 6010. https://doi.org/10.15829/1560-4071-2025-6010.

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Aim. To assess the effectiveness of vaccination against Omicron and Delta variants according to the international registry "Dynamics Analysis of Comorbidities in SARS-CoV-2 Survivors" (AKTIV-4).Material and methods. The AKTIV-4 registry included men and women over 18 years of age with a diagnosis of coronavirus disease 2019 (COVID-19) (oropharyngeal and nasopharyngeal swabs, SARS-CoV-2 antibody titers, typical computed tomography performance), undergoing hospital treatment. A total of 3543 patients from 25 medical centers in 7 countries (the Russian Federation, the Republic of Armenia, the Rep
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Dr., Praveen G.S, Fathahudeen. A. Dr., Reshmi S. Nair Dr., et al. "Predictive accuracy of CURB-65 as comparedto PSI scorein the severity assessment of community acquired pneumonia." International Journal of Medical Research and Review 7, no. 3 (2019): 182–89. https://doi.org/10.17511/ijmrr.2019.i03.06.

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Introduction: Pneumonia Severity Index (PSI) and CURB-65 rule for community acquired pneumonia (CAP) have been developed to stratify patients based on mortality. Lack of a risk stratifying score like PSI or CURB-65 can lead to significant delay in starting treatment. This study was conducted to find out the ability of CURB-65 score and PSI to predict clinically relevant outcomes. Methods: 78 patients diagnosed as CAP admitted to a tertiary care hospital were enrolled into the study. Detailed clinical history was noted and CURB-65 and PSI scores were given with the help of a structured question
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Norcini, John J., John R. Boulet, Amy Opalek, and W. Dale Dauphinee. "Specialty Board Certification Rate as an Outcome Metric for GME Training Institutions: A Relationship With Quality of Care." Evaluation & the Health Professions 43, no. 3 (2018): 143–48. http://dx.doi.org/10.1177/0163278718796128.

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Educational outcome measures, known to be associated with the quality of care, are needed to support improvements in graduate medical education (GME). This retrospective observational study sought to determine whether there was a relationship between the specialty board certification rates of GME training institutions and the quality of care delivered by their graduates. It is based on 7 years of hospitalizations in Pennsylvania ( N = 354,767) with diagnoses of acute myocardial infarction, congestive heart failure, gastrointestinal hemorrhage, or pneumonia. The 2,265 attending physicians were
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Krongsut, Sarawut, Wipasiri Naraphong, Pannaporn Thongsuk, and Panupong Tantirat. "COMPARISON OF THE EFFECTIVENESS OF REMDESIVIR VERSUS FAVIPIRAVIR ON CLINICAL IMPROVEMENT AND MORTALITY AMONG PATIENTS WITH COVID-19 PNEUMONIA: A RETROSPECTIVE SINGLE-CENTER STUDY." Journal of Southeast Asian Medical Research 7 (May 13, 2023): e0151. http://dx.doi.org/10.55374/jseamed.v7.151.

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Background: Antiviral drug administration in the early phase of COVID-19 during peak viremia can reduce the progression to severe disease. The optimal antiviral treatment against severe coronavirus disease 2019 (COVID‐19) has not been proven.&#x0D; Objective: The study aimed to examine the effectiveness of remdesivir versus favipiravir to treat patients with COVID-19 pneumonia on clinical improvement and mortality.&#x0D; Methods: This retrospective observational cohort study was conducted in the modular intensive care unit and cohort ward from 1 June 2021 to 31 December 2021. Patients were scr
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Adair, Marcus J., Samer Alharthi, Jorge Ortiz, et al. "Robotic Surgery is More Expensive with Similar Outcomes in Sleeve Gastrectomy: Analysis of the NIS Database." American Surgeon 85, no. 1 (2019): 39–45. http://dx.doi.org/10.1177/000313481908500120.

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The aim of this study was to compare postoperative outcomes after robotic-assisted and laparoscopic bariatric sleeve gastrectomy (SG). Sleeve gastrectomy is traditionally performed using laparoscopic techniques. Robotic-assisted surgery enables surgeons to perform minimally invasive SG, but with unknown benefits. Using a national database, we compared postoperative outcomes after laparoscopic SG and robotic-assisted SG. National data from individuals undergoing elective SG in the National Inpatient Sample database between 2011 and 2013 were analyzed. Propensity score matching was used to match
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Vukadinovic, Dubravka, Natalija Samardzic, Slobodan Jankovic, Marijana Tomic-Smiljanic, Radisa Pavlovic, and Srdjan Stefanovic. "Factors associated with early treatment failure in adult hospitalized patients with community-acquired pneumonia." Vojnosanitetski pregled 74, no. 9 (2017): 803–13. http://dx.doi.org/10.2298/vsp160211085v.

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Background/Aim. Early treatment failure (ETF) in patients hospitalized for community-acquired pneumonia (CAP) is associated with prolonged hospitalization, increased risk of mortality and high treatment costs. The aim of this study was to analyze the relative importance of factors influencing ETF in hospitalized adult patients with CAP that are still insufficiently explored. Methods. A retrospective case-control study was carried out on a sample of 126 adult patients treated for serious CAP at the Clinic for Pulmonary Diseases, Clinical Center of Serbia, Belgrade, Serbia, during the 5-year per
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Almutairi, Abdulmajed, Farhan Alenezi, Hani Tamim, et al. "The prevalence of acute kidney injury in patients with community-acquired pneumonia who required mechanical ventilation." Annals of Saudi Medicine 44, no. 2 (2024): 104–10. http://dx.doi.org/10.5144/0256-4947.2024.104.

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BACKGROUND: Community-acquired pneumonia (CAP) is a common reason for intensive care unit (ICU) admission and sepsis. Acute kidney injury (AKI) is a frequent complication of community-acquired pneumonia and is associated with increased short- and long-term morbidity and mortality and healthcare costs. OBJECTIVE: Describe the prevalence of AKI in patients with CAP requiring mechanical ventilation and evaluate its association with inhospital mortality. DESIGN: Retrospective cohort SETTING: Intensive care unit PATIENTS AND METHODS: We included patients with CAP on mechanical ventilation. Patients
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Kumari, Minu, Neha Rastogi, Rajesh Malhotra, and Purva Mathur. "Clinico-microbiological profile of healthcare associated pneumonia in critically ill patients at level-I trauma centre of India." Journal of Laboratory Physicians 10, no. 04 (2018): 406–9. http://dx.doi.org/10.4103/jlp.jlp_85_18.

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ABSTRACT INTRODUCTION: Device-associated infections constitute the majority of health-care infections in Intensive Care Units (ICUs). Trauma patients are more prone to acquire such infections; ventilator-associated pneumonia (VAP) being the most common Health care associated infections (HAI) in ICU has serious implications such as increased morbidity, prolonged hospital stay, and mortality. This study aims to compare the clinicomicrobiological profile of VAP and non-VAP trauma patients at Level I trauma center. MATERIALS AND METHODS: A 4-year retrospective study of prospectively maintained dat
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Parra, Daniela, Manuela Sáenz-Valcárcel, Laura Claverias, et al. "4221 Lower Serum TWEAK Concentration is a Biomarker for Mortality in Community Acquired Pneumonia." Journal of Clinical and Translational Science 4, s1 (2020): 139. http://dx.doi.org/10.1017/cts.2020.411.

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OBJECTIVES/GOALS: To determine the relationship among serum concentration of tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) and mortality in community-acquired pneumonia (CAP) patients. METHODS/STUDY POPULATION: This is a multicenter 2-year cohort study in Spain, designed to better understand the role of sTWEAK concentrations in CAP patients. CAP patients were prospectively enrolled in two University hospitals and sTWEAK was measured within the first 24 hours of ICU admission. Samples were collected and stored for laboratory analyses. To detect sTWEAK in human samples, we u
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Patel, Munna Lal, Rekha Sachan, and Rahul Kumar. "A Comparative Study of Community-acquired Acute Kidney Injury and Hospital-acquired Acute Kidney Injury from a Tertiary Care Hospital in North India." Annals of African Medicine 23, no. 3 (2024): 420–28. http://dx.doi.org/10.4103/aam.aam_110_23.

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Background: In this observational study, clinical characteristics, etiologies, and outcomes of patients admitted to the hospital with community-acquired acute kidney injury (CAAKI) have been compared in contrast to those who hospital-acquired Acute Kidney Injury (HAAKI). Methods: This was a prospective study of adults aged 18 years or above diagnosed with acute kidney injury (AKI) over a period of 17 months at a tertiary care hospital. Results: 230 patients had AKI with the mean age of the study population being 45.33 ± 12.68 years. 178 (77.4%) patients were enrolled from medical unit, 25 (10.
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Mansutti, Irene, Luisa Saiani, and Alvisa Palese. "Delirium in patients with ischaemic and haemorrhagic stroke: findings from a scoping review." European Journal of Cardiovascular Nursing 18, no. 6 (2019): 435–48. http://dx.doi.org/10.1177/1474515119846226.

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Background: Delirium is a complex syndrome characterised by disturbances in attention and awareness, associated with alterations in cognitive functions, which can emerge in a time frame of hours or days and tend to fluctuate in severity over time. Delirium is a clinical manifestation of the brain’s vulnerability and diminished resilience to insult. Stroke patients are particularly vulnerable to delirium episodes. Aims: The aim of this study was to map: (a) studies focused on ischaemic or haemorrhagic post-stroke delirium; (b) factors that have been investigated as being possibly associated wit
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Sheehan, Brian M., Areg Grigorian, Sahil Gambhir, et al. "Early Tracheostomy for Severe Pediatric Traumatic Brain Injury is Associated with Reduced Intensive Care Unit Length of Stay and Total Ventilator Days." Journal of Intensive Care Medicine 35, no. 11 (2019): 1346–51. http://dx.doi.org/10.1177/0885066619870153.

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Objectives: To determine whether, similar to adults, early tracheostomy in pediatric patients with severe traumatic brain injury (TBI) improves inhospital outcomes including ventilator days, intensive care unit (ICU) length of stay (LOS), and total hospital LOS when compared to late tracheostomy. Design: Retrospective cohort analysis. Setting: The Pediatric Trauma Quality Improvement Program (TQIP) database Patients: One hundred twenty-seven pediatric patients &lt;16 years old with severe (&gt;3) abbreviated injury scale TBI who underwent early (days 1-6) or late (day ≥7) tracheostomy between
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Shirokov, N. E., E. I. Yaroslavskaya, D. V. Krinochkin, and N. A. Osokina. "Dynamics of global and segmental strain as a marker of right ventricular contractility recovery in patients after COVID-19 pneumonia." Russian Journal of Cardiology 28, no. 1 (2022): 5212. http://dx.doi.org/10.15829/1560-4071-2023-5212.

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Aim. To study the changes of morphological and functional right ventricular (RV) parameters depending on the severity of coronavirus infection 2019 (COVID-19) pneumonia over long-term follow-up.Material and methods. A total of 200 patients (men, 51,5%, mean age, 51,4±10,9 years) were examined at 2 control visits (3, 12 months after receiving two negative polymerase chain reaction tests). Patients were divided into following groups: group I (n=94) — lung tissue involvement ≥50% according to inhospital chest computed tomography (chest CT), group II (n=106) — lung tissue involvement˂50% according
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Vidakovic, Stefan, Ranko Raicevic, Marija Grunauer, Viktor Pasovski, and Vesna Suljagic. "Risk factors for healthcare associated infections and in-hospital mortality in neurological intensive care unit in tertiary hospital in Belgrade, Serbia: A prospective cohort study." Vojnosanitetski pregled 77, no. 10 (2020): 1060–66. http://dx.doi.org/10.2298/vsp180422184v.

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Background/Aim. Patients in a neurologic intensive care unit (ICU) are especially susceptible to healthcare-associated infections (HAIs). HAIs are cause of significant morbidity and mortality. Aim of this study was to assess the incidence of HAIs, to identify significant risk factors (RFs) and causative microorganisms for HAIs and to identify RFs for inhospital mortality in a neurological ICU. Methods. A prospective cohort study was conducted in the six-bed ICU of the Clinic for Neurology, Military Medical Academy in Belgrade from January 1, 2014 to December 31, 2016. Active surveillance on HA
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Md., Kamran Hashmi, Ranjan Kumar Ravi, and Jha Sanjay. "To Study the Severe Bilateral Lower Limb Ischemia in a Patient with COVID-19 Infection: Multi-Centre, Observational, and Retrospective Study." International Journal of Current Pharmaceutical Review and Research 16, no. 04 (2024): 704–10. https://doi.org/10.5281/zenodo.12804408.

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Aim: To study the severe bilateral lower limb ischemia in a patient with COVID-19 infection.Material and Methods: This study was conducted in the Department of Radiology, Darbhanga medical collegeand Hospital, Darbhanga, and Bhagwan Mahavir Institute of Medical Sciences, Pawapuri, Bihar, India for oneyear. This was a multi-centre, observational, and retrospective study. Records of all patients &ge;18 years of ageadmitted with ALI and a confirmed diagnosis of COVID-19 infection were retrospectively examined. Datacollected included demographics, co-morbidities, biological findings, COVID-19 pneu
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Coldewey, M., W. Dippold, J. Beule, J. O. Balzer, and K. Keller. "Simplified CRB-65 for risk stratification and predicting prognosis in acute pulmonary embolism." Phlebologie 44, no. 04 (2015): 192–99. http://dx.doi.org/10.12687/phleb2251-4-2015.

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SummaryBackground: Pulmonary embolism (PE) and community acquired pneumonia (CAP) are potentially life-threatening diseases. In CAP CRB-65 is used for risk stratification and prognosis prediction. The aim of this study was to examine a simplified CRB-65 (sCRB-65) for predicting prognosis in PE.Methods: We retrospectively analyzed the data of 182 PE patients. Patients were, according to the score of sCRB-65 (respectively 1 point for dyspnoea, systolic blood pressure &lt; 90 mmHg or diastolic blood pressure60 mmHg, age65years), subdivided in risk-classes 1–4.Risk classes were compared with Krusk
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Paranjape, Kiran, Simon Lévesque, and Sébastien P. Faucher. "Bacterial Antagonistic Species of the Pathogenic Genus Legionella Isolated from Cooling Tower." Microorganisms 10, no. 2 (2022): 392. http://dx.doi.org/10.3390/microorganisms10020392.

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Legionella pneumophila is the causative agent of Legionnaires’ disease, a severe pneumonia. Cooling towers are a major source of large outbreaks of the disease. The growth of L. pneumophila in these habitats is influenced by the resident microbiota. Consequently, the aim of this study was to isolate and characterize bacterial species from cooling towers capable of inhibiting several strains of L. pneumophila and one strain of L. quinlivanii. Two cooling towers were sampled to isolate inhibiting bacterial species. Seven inhibitory isolates were isolated, through serial dilution plating and stre
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Poovieng, Jaturon, Boonsub Sakboonyarat, and Worapong Nasomsong. "Bacterial etiology and mortality rate in community-acquired pneumonia, healthcare-associated pneumonia and hospital-acquired pneumonia in Thai university hospital." Scientific Reports 12, no. 1 (2022). http://dx.doi.org/10.1038/s41598-022-12904-z.

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AbstractPneumonia is caused by infection at the pulmonary parenchyma which constitutes a crucial risk factor for morbidity and mortality. We aimed to determine the mortality rate and its risk factors as well as etiology among inpatients with community-acquired pneumonia (CAP), hospital-acquired pneumonia (HAP) and healthcare-associated pneumonia (HCAP). A hospital-based retrospective cohort study was conducted in a university hospital located in Bangkok, Thailand. A total of 250 inpatients with pneumonia was included in the present study. The inhospital mortality rate was 1.25 (95% CI 0.99–1.5
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Mittal, Kartik, Minakshi Dhar, Monika Pathania, Dipesh Jha, and Vartika Saxena. "A comparative study of mortality differences and associated characteristics among elderly and young adult patients hospitalised with COVID-19 in India." BMC Geriatrics 23, no. 1 (2023). http://dx.doi.org/10.1186/s12877-023-03955-6.

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Abstract Introduction Studies have shown that elderly have been disproportionately impacted by COVID pandemic. They have more comorbidities, lower pulmonary reserve, greater risk of complications, more significant resource utilization, and bias towards receiving lower-quality treatment. Objectives This research aims to determine the characteristics of those who died inhospital due to COVID illness, and to compare these factors between elderly and young adults. Methods We conducted a large retrospective study at a government run center in Rishikesh, India, from 1st May 2020 till 31st May 2021,
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Muraleedharan, Manesh, and Alaka Omprakash Chandak. "Developing a conceptual model for studying various points of delays and underlying factors in the emergency healthcare system." Emergency Care Journal 18, no. 1 (2022). http://dx.doi.org/10.4081/ecj.2022.10255.

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To review various literature related to emergency healthcarerelated delays and synthesize a conceptual framework for future research. Critical Interpretative Synthesis is employed to analyze and develop themes from selected articles. A total of 25 articles were selected for analysis after the careful selection process. Diseases including acute heart disease, stroke, pneumonia, infections, and gastrointestinal disorders were included. During analysis, three major phases of delays emerged: pre-hospital delay, inhospital delay, and ambulance off-load delay. Various factors, including socioeconomi
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Neupane, Binod, Stephen D. Walter, Paul Krueger, Tom Marrie, and Mark Loeb. "Predictors of inhospital mortality and re-hospitalization in older adults with community-acquired pneumonia: a prospective cohort study." BMC Geriatrics 10, no. 1 (2010). http://dx.doi.org/10.1186/1471-2318-10-22.

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Ogero, Morris, John Ndiritu, Rachel Sarguta, Timothy Tuti, and Samuel Akech. "Pediatric prognostic models predicting inhospital child mortality in resource‐limited settings: An external validation study." Health Science Reports 6, no. 8 (2023). http://dx.doi.org/10.1002/hsr2.1433.

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AbstractBackground and AimsPrognostic models provide evidence‐based predictions and estimates of future outcomes, facilitating decision‐making, patient care, and research. A few of these models have been externally validated, leading to uncertain reliability and generalizability. This study aims to externally validate four models to assess their transferability and usefulness in clinical practice. The models include the respiratory index of severity in children (RISC)‐Malawi model and three other models by Lowlavaar et al.MethodsThe study used data from the Clinical Information Network (CIN) t
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Sadigov, Alizamin. "HIV-Associated Community– Acquired Pneumonia: Assessment of Risk Factors for Poor Patient Outcomes from a Single Center Experience." Microbiology & Infectious Diseases 7, no. 2 (2023). http://dx.doi.org/10.33425/2639-9458.1174.

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Assessment of risk factors which may predict poor outcomes for patients with community-acquired pneumonia (CAP) in individuals with HIV is important for further evaluation of possibility their modification and through that the reduction mortality rate and improved patient outcomes. We aimed to investigate the risk factors for CAP in patients with HIV infection in term on their modification and through that reduction associated poor outcomes in such patients. We conducted a retrospective cohort study involving patients with diagnosed CAP who were admitted to the pulmonary and critical care medi
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Singh, Jasvinder A., and John D. Cleveland. "Hospitalized Infections in People with Osteoarthritis: A National U.S. Study." Journal of Rheumatology, August 1, 2020, jrheum.191383. http://dx.doi.org/10.3899/jrheum.191383.

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Objective To study the incidence, time-trends and outcomes of serious infections in people with osteoarthritis. Methods We used the 1998-2016 U.S. National Inpatient Sample data. We examined the epidemiology of five hospitalized, i.e., serious infections (opportunistic infections (OI), skin and soft tissue infections (SSTI), urinary tract infection (UTI), pneumonia, and sepsis/bacteremia) in people with osteoarthritis, using recommended weights. We performed multivariable-adjusted logistic regression analyses to analyze factors associated with healthcare utilization (hospital charges, length o
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Qian, Jie, Ruoyan Qin, Liang Hong, et al. "Characteristics and clinical outcomes of patients with lung cancer requiring ICU admission: a retrospective analysis based on the MIMIC-III database." Emergency Cancer Care 2, no. 1 (2023). http://dx.doi.org/10.1186/s44201-022-00017-2.

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Abstract Background Lung cancer (LC) is the most common solid tumor type in the intensive care unit (ICU). This study investigated the characteristics of LC patients admitted to the ICU, the major reasons for their admission, short-term mortality, and associated risk factors. Methods Patients with LC were retrospectively identified in the publicly available, large-scale, single-center database Medical Information Mart for Intensive Care (MIMIC) III. Demographic and clinical characteristics, including age, sex, smoking history, comorbidities, type of admission to ICU, major diagnoses, illness s
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Soliman, Soliman Belal, Salwa Hassan Ahmed, Hanan El-Sayed Zaghla, Mohanad Zakarya, Mohamed Shaaban Mousa, and Osama Amin Abdelhamid. "Serum ferritin-procalcitonin ratio as a predictor of outcomes in hospitalized patients with COVID-19 pneumonia." Egyptian Journal of Bronchology 19, no. 1 (2025). https://doi.org/10.1186/s43168-025-00403-4.

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Abstract Background To identify the correlation between the ferritin-procalcitonin ratio and clinical outcomes including inhospital mortality and the requirement for mechanical ventilation in patients hospitalized with COVID-19. Methods This is a prospective observational cohort study, conducted on 60 patients diagnosed with COVID-19 admitted to the intensive care units of Kasr Al Ainy University Hospital. All patients had positive PCR results for COVID-19. All patients were assessed regarding the following inflammatory markers (CRP, ferritin, procalcitonin) and also the serum-ferritin procalc
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Edathadathil, Fabia, Georg Gutajhr, T. S. Dipu, and Sanjeev Singh. "P-829. Determination of novel clinical phenotypes among sepsis patients from an Indian sepsis registry." Open Forum Infectious Diseases 12, Supplement_1 (2025). https://doi.org/10.1093/ofid/ofae631.1021.

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Abstract Background Sepsis is a dysregulated host immune response with heterogenous clinical presentation reflected in its high dimensional data and with distinct epidemiological profile endemic to LMICs such as India. The study aims to identify and estimate the prevalence of clinical phenotypes from retrospective data of sepsis patients from a South Indian registry. Characteristics of the identified clusters and outcomes Methods The registry enrolled all adult patients admitted through the emergency department with a presumed diagnosis of sepsis following Surviving Sepsis Guidelines(SSG) crit
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Tariq, Nauman, Saqib Chaudhary, Malik M. Adil, Maryam Saeed, and Adnan I. Qureshi. "Abstract WP65: Outcomes Of Thrombolytic Treatment For Acute Ischemic Stroke In Dialysis Dependant Patients In The United States." Stroke 44, suppl_1 (2013). http://dx.doi.org/10.1161/str.44.suppl_1.awp65.

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Objective: To determine the outcomes of dialysis dependant patients who suffered from ischemic stroke and were treated with IV thrombolytics in United States Methods: We analyzed the data from Nationwide Inpatient Sample (NIS 2005-2008) for all thrombolytic treated patients presenting with acute ischemic stroke with or without dialysis dependence. Patients were identified using the ICD 9 CM codes. Baseline characteristics, inhospital complications including secondary intracerebral hemorrhage (ICH), DVT, UTI, sepsis, pneumonia, sepsis, pulmonary embolism and discharge outcomes (mortality, minim
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Ordóñez-Enireb, Eunice, Roberto V. Cucalón, Diana Cárdenas, et al. "Antarctic fungi with antibiotic potential isolated from Fort William Point, Antarctica." Scientific Reports 12, no. 1 (2022). http://dx.doi.org/10.1038/s41598-022-25911-x.

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AbstractThe Antarctic continent is one of the most inhospitable places on earth, where living creatures, mostly represented by microorganisms, have specific physiological characteristics that allow them to adapt to the extreme environmental conditions. These physiological adaptations can result in the production of unique secondary metabolites with potential biotechnological applications. The current study presents a genetic and antibacterial characterization of four Antarctic fungi isolated from soil samples collected in Pedro Vicente Maldonado Scientific Station, at Fort William Point, Green
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Moss, Caitlin E., and Craig R. Roy. "InSeq analysis of defined Legionella pneumophila libraries identifies a transporter-encoding gene cluster important for intracellular replication in mammalian hosts." mBio, October 4, 2024. http://dx.doi.org/10.1128/mbio.01955-24.

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ABSTRACT Legionella pneumophila is an intracellular bacterial pathogen that replicates inside human alveolar macrophages to cause a severe pneumonia known as Legionnaires’ disease. L. pneumophila requires the Dot/Icm Type IV secretion system to deliver hundreds of bacterial proteins to the host cytosol that manipulate cellular processes to establish a protected compartment for bacterial replication known as the Legionella- containing vacuole. To better understand mechanisms apart from the Dot/Icm system that support survival and replication in this vacuole, we used transposon insertion sequenc
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