Journal articles on the topic 'INKT cells'
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Uddin, Mohammad Nizam, Dil Afroz Sultana, Kyle J. Lorentsen, et al. "Transcription factor Bcl11b sustains iNKT1 and iNKT2 cell programs, restricts iNKT17 cell program, and governs iNKT cell survival." Proceedings of the National Academy of Sciences 113, no. 27 (2016): 7608–13. http://dx.doi.org/10.1073/pnas.1521846113.
Full textMaas-Bauer, Kristina, Juliane K. Lohmeyer, Toshihito Hirai, et al. "Invariant natural killer T-cell subsets have diverse graft-versus-host-disease–preventing and antitumor effects." Blood 138, no. 10 (2021): 858–70. http://dx.doi.org/10.1182/blood.2021010887.
Full textMaas-Bauer, Kristina, Federico Simonetta, Toshihito Hirai, et al. "Invariant Natural Killer T Cell Subsets Have Diverse Functions: iNKT2 and iNKT17 Protect from Graft-Versus-Host-Disease, Whereas iNKT1 Have Antitumor Potential." Blood 132, Supplement 1 (2018): 475. http://dx.doi.org/10.1182/blood-2018-99-113673.
Full textPatel, Nishant P., Peng Guan, Devika Bahal, et al. "Cancer Immunotherapeutic Potential of NKTT320, a Novel, Invariant, Natural Killer T Cell-Activating, Humanized Monoclonal Antibody." International Journal of Molecular Sciences 21, no. 12 (2020): 4317. http://dx.doi.org/10.3390/ijms21124317.
Full textChen, Dongzhi, Wenbin Xu, Jingfang Teng, et al. "Migration, Distribution, and Safety Evaluation of Specific Phenotypic and Functional Mouse Spleen-Derived Invariant Natural Killer T2 Cells after Adoptive Infusion." Mediators of Inflammation 2021 (December 8, 2021): 1–11. http://dx.doi.org/10.1155/2021/5170123.
Full textJahnke, Simona, Hannes Schmid, Kathy-Ann Secker, et al. "Invariant Natural Killer T Cells from Donor Lymphocyte Infusions (DLI-iNKTs) Contribute to Anti-Tumor Immunity after Allogeneic Hematopoietic Cell Transplantation." Blood 132, Supplement 1 (2018): 3340. http://dx.doi.org/10.1182/blood-2018-99-111745.
Full textCastillo, Eliseo F., Luis F. Acero, Spencer W. Stonier, Dapeng Zhou, and Kimberly S. Schluns. "Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation." Blood 116, no. 14 (2010): 2494–503. http://dx.doi.org/10.1182/blood-2010-03-277103.
Full textKanda, Masatoshi, Hiroyuki Yamanaka, Satoshi Kojo та ін. "Transcriptional regulator Bhlhe40 works as a cofactor of T-bet in the regulation of IFN-γ production in iNKT cells". Proceedings of the National Academy of Sciences 113, № 24 (2016): E3394—E3402. http://dx.doi.org/10.1073/pnas.1604178113.
Full textPurbhoo, Marco, Burcu Yigit, Darrian Moskowitz, et al. "400 Persistence and tissue distribution of agent-797 – a native allogeneic iNKT cell-therapy drug product." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (2021): A432. http://dx.doi.org/10.1136/jitc-2021-sitc2021.400.
Full textMetelitsa, Leonid S., Hong-Wei Wu, Hong Wang, et al. "Natural Killer T Cells Infiltrate Neuroblastomas Expressing the Chemokine CCL2." Journal of Experimental Medicine 199, no. 9 (2004): 1213–21. http://dx.doi.org/10.1084/jem.20031462.
Full textSmith, Drake J., Siyuan Liu, Sunjong Ji, et al. "Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cells." Proceedings of the National Academy of Sciences 112, no. 5 (2015): 1523–28. http://dx.doi.org/10.1073/pnas.1424877112.
Full textDempsey, Laurie A. "Limiting iNKT cells." Nature Immunology 15, no. 3 (2014): 222. http://dx.doi.org/10.1038/ni.2839.
Full textHe, Qing, Linlin Liu, Qiaoyu Yang, et al. "Invariant natural killer T cells promote immunogenic maturation of lung dendritic cells in mouse models of asthma." American Journal of Physiology-Lung Cellular and Molecular Physiology 313, no. 6 (2017): L973—L990. http://dx.doi.org/10.1152/ajplung.00340.2016.
Full textWermeling, Fredrik, Sara M. Lind, Emilie Domange Jordö, Susanna L. Cardell, and Mikael C. I. Karlsson. "Invariant NKT cells limit activation of autoreactive CD1d-positive B cells." Journal of Experimental Medicine 207, no. 5 (2010): 943–52. http://dx.doi.org/10.1084/jem.20091314.
Full textQin, Yingyu, Sejin Oh, Sojung Lim, Jung Hoon Shin, Min Sang Yoon, and Se-Ho Park. "Invariant NKT cells facilitate cytotoxic T-cell activation via direct recognition of CD1d on T cells." Experimental & Molecular Medicine 51, no. 10 (2019): 1–9. http://dx.doi.org/10.1038/s12276-019-0329-9.
Full textVomhof-DeKrey, Emilie E., Jennifer Yates, Thomas Hägglöf, et al. "Cognate interaction with iNKT cells expands IL-10–producing B regulatory cells." Proceedings of the National Academy of Sciences 112, no. 40 (2015): 12474–79. http://dx.doi.org/10.1073/pnas.1504790112.
Full textMilpied, Pierre, Bérangère Massot, Amédée Renand, et al. "IL-17–producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression." Blood 118, no. 11 (2011): 2993–3002. http://dx.doi.org/10.1182/blood-2011-01-329268.
Full textYamaura, Ayako, Chie Hotta, Masatoshi Nakazawa, Luc Van Kaer та Mutsuhiko Minami. "Human invariant Vα24+ natural killer T cells acquire regulatory functions by interacting with IL-10–treated dendritic cells". Blood 111, № 8 (2008): 4254–63. http://dx.doi.org/10.1182/blood-2007-04-085142.
Full textTorreno-Pina, Juan A., Carlo Manzo, Mariolina Salio, et al. "The actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells." Proceedings of the National Academy of Sciences 113, no. 6 (2016): E772—E781. http://dx.doi.org/10.1073/pnas.1514530113.
Full textLoureiro, J. Pedro, Mariana S. Cruz, Ana P. Cardoso, Maria J. Oliveira, and M. Fátima Macedo. "Human iNKT Cells Modulate Macrophage Survival and Phenotype." Biomedicines 10, no. 7 (2022): 1723. http://dx.doi.org/10.3390/biomedicines10071723.
Full textSong, Weihua, Hans J. J. van der Vliet, Ruojie Wang, et al. "In Vitro Generation of Highly-Purified Functional Invariant NKT Cells: A Strategy for Immunotherapy in Multiple Myeloma." Blood 106, no. 11 (2005): 5183. http://dx.doi.org/10.1182/blood.v106.11.5183.5183.
Full textMalard, Florent, Myriam Labopin, Patrice Chevallier, et al. "Larger number of invariant natural killer T cells in PBSC allografts correlates with improved GVHD-free and progression-free survival." Blood 127, no. 14 (2016): 1828–35. http://dx.doi.org/10.1182/blood-2015-12-688739.
Full textPark, Hyun Jung, Sung Won Lee, Luc Van Kaer та Seokmann Hong. "CD1d-Dependent iNKT Cells Control DSS-Induced Colitis in a Mouse Model of IFNγ-Mediated Hyperinflammation by Increasing IL22-Secreting ILC3 Cells". International Journal of Molecular Sciences 22, № 3 (2021): 1250. http://dx.doi.org/10.3390/ijms22031250.
Full textBrigl, Manfred, Raju V. V. Tatituri, Gerald F. M. Watts, et al. "Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection." Journal of Experimental Medicine 208, no. 6 (2011): 1163–77. http://dx.doi.org/10.1084/jem.20102555.
Full textMoreno, María, Berber M. Mol, Silvia von Mensdorff-Pouilly, et al. "Differential indirect activation of human invariant natural killer T cells by Toll-like receptor agonists." Immunotherapy 1, no. 4 (2009): 557–70. http://dx.doi.org/10.2217/imt.09.30.
Full textAoki, Takahiro, Mariko Takami, Tomozumi Takatani, et al. "Invariant NKT Cells Recognize Leukemia Cells with T-Cell and NK Receptors in a CD1d-Independent Manner." Blood 134, Supplement_1 (2019): 3225. http://dx.doi.org/10.1182/blood-2019-121817.
Full textMallevaey, Thierry, Josette Fontaine, Laetitia Breuilh, et al. "Invariant and Noninvariant Natural Killer T Cells Exert Opposite Regulatory Functions on the Immune Response during Murine Schistosomiasis." Infection and Immunity 75, no. 5 (2007): 2171–80. http://dx.doi.org/10.1128/iai.01178-06.
Full textFoley, J. F. "iNKT Cells Reduce Obesity." Science Signaling 5, no. 243 (2012): ec249-ec249. http://dx.doi.org/10.1126/scisignal.2003632.
Full textMIYAKE, Sachiko. "Immunoregulation by iNKT Cells." YAKUGAKU ZASSHI 129, no. 6 (2009): 649–53. http://dx.doi.org/10.1248/yakushi.129.649.
Full textBedard, Melissa, Dilip Shrestha, David A. Priestman, et al. "Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells." Proceedings of the National Academy of Sciences 116, no. 47 (2019): 23671–81. http://dx.doi.org/10.1073/pnas.1910097116.
Full textScheuplein, Felix, Abraham Thariath, Robert Mashal, and Robert Schaub. "Mouse Invariant TCR Specific Monoclonal Antibody NKT14: A Novel Tool To Manipulate Invariant NKT Cell Function In Vivo." Blood 122, no. 21 (2013): 3478. http://dx.doi.org/10.1182/blood.v122.21.3478.3478.
Full textHsu, Chien-Ya, Yu-Shan Chueh, Ming-Ling Kuo, et al. "Expansion of invariant natural killer T cells from systemic lupus erythematosus patients by alpha-Galactosylceramide and IL-15." PLOS ONE 16, no. 12 (2021): e0261727. http://dx.doi.org/10.1371/journal.pone.0261727.
Full textMavers, Melissa, Derek Hollingsworth, Chaiyaporn Boonchalermvichian, et al. "Engineering Human Invariant Natural Killer T (iNKT) Cells to Overexpress Immunomodulatory Cytokines." Blood 138, Supplement 1 (2021): 3888. http://dx.doi.org/10.1182/blood-2021-153975.
Full textChuang, Ya-Ting, Wan-Chu Chuang, Chih-Chun Liu та ін. "Ets1 Promotes the Differentiation of Post-Selected iNKT Cells through Regulation of the Expression of Vα14Jα18 T Cell Receptor and PLZF". International Journal of Molecular Sciences 22, № 22 (2021): 12199. http://dx.doi.org/10.3390/ijms222212199.
Full textImataki, Osamu, Makito Tanaka, Alla Berezovskaya, Marcus O. Butler, Lee M. Nadler та Naoto Hirano. "Endogenous Ligands Selectively Stimulate Highly Avid Autoreactive Human Invariant Natural Killer T Cells with Distinctive T-Cell Receptor Vβ11 CDR3 Sequence Motifs". Blood 118, № 21 (2011): 999. http://dx.doi.org/10.1182/blood.v118.21.999.999.
Full textSedimbi, Saikiran K., Thomas Hägglöf, Manasa G. Garimella, et al. "Combined proinflammatory cytokine and cognate activation of invariant natural killer T cells enhances anti-DNA antibody responses." Proceedings of the National Academy of Sciences 117, no. 16 (2020): 9054–63. http://dx.doi.org/10.1073/pnas.1920463117.
Full textSpanoudakis, Emmanouil, Menelaos Papoutselis, Ioannis Kotsianidis, et al. "Over-Expression of RANKL In Invariant NKT Cells Is Characteristic of Active Myeloma but Not of MGUS or Asymptomatic Myeloma." Blood 116, no. 21 (2010): 4049. http://dx.doi.org/10.1182/blood.v116.21.4049.4049.
Full textYang, Jun-Qi, Yonghua Zhou, and Ram Raj Singh. "Effects of Invariant NKT Cells on Parasite Infections and Hygiene Hypothesis." Journal of Immunology Research 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/2395645.
Full textFedeli, Maya, Michela Riba, Jose Manuel Garcia Manteiga та ін. "miR-17∼92 family clusters control iNKT cell ontogenesis via modulation of TGF-β signaling". Proceedings of the National Academy of Sciences 113, № 51 (2016): E8286—E8295. http://dx.doi.org/10.1073/pnas.1612024114.
Full textYu, Jennifer C., Gene W. Lin, Jenny Kim, and Joel Linden. "Activated Human iNKT Cells in Pediatric Sickle Cell Disease Patients and in Culture Upregulate Ectonucleotidase CD39 and Adenosine a2A Receptor." Blood 124, no. 21 (2014): 2734. http://dx.doi.org/10.1182/blood.v124.21.2734.2734.
Full textLi, Yan-Ruide, Yang Zhou, Matthew Wilson та ін. "Tumor-Localized Administration of α-GalCer to Recruit Invariant Natural Killer T Cells and Enhance Their Antitumor Activity against Solid Tumors". International Journal of Molecular Sciences 23, № 14 (2022): 7547. http://dx.doi.org/10.3390/ijms23147547.
Full textDu, Jing, Katelyn Paz, Govindarajan Thangavelu, et al. "Invariant natural killer T cells ameliorate murine chronic GVHD by expanding donor regulatory T cells." Blood 129, no. 23 (2017): 3121–25. http://dx.doi.org/10.1182/blood-2016-11-752444.
Full textSchneidawind, Dominik, Jeanette Baker, Corina Buechele, Everett H. Meyer, and Robert S. Negrin. "Third Party Invariant Natural Killer T Cells Protect from Graft-Versus-Host Disease Lethality through Expansion of Donor CD4+FoxP3+ Regulatory T Cells." Blood 124, no. 21 (2014): 3825. http://dx.doi.org/10.1182/blood.v124.21.3825.3825.
Full textStrong, Beverly SI, Tess J. Newkold, Amanda E. Lee, Lucas E. Turner, Jonathon W. Heusel, and Aimen F. Shaaban. "Asymmetric Allospecific Signals Shape iNKT Cell Lineage Fate Decisions." Blood 126, no. 23 (2015): 4274. http://dx.doi.org/10.1182/blood.v126.23.4274.4274.
Full textThedrez, Aurelie, Claudia de Lalla, Sophie Allain, et al. "CD4 engagement by CD1d potentiates activation of CD4+ invariant NKT cells." Blood 110, no. 1 (2007): 251–58. http://dx.doi.org/10.1182/blood-2007-01-066217.
Full textHavenar-Daughton, Colin, Shamin Li, Kamel Benlagha та Julien C. Marie. "Development and function of murine RORγt+ iNKT cells are under TGF-β signaling control". Blood 119, № 15 (2012): 3486–94. http://dx.doi.org/10.1182/blood-2012-01-401604.
Full textLinden, Joel, Gene Lin, Jennifer C. Yu, Donna S. Neuberg, David G. Nathan та Joshua J. Field. "NF-κB Activation Mediates Induction Of Anti-Inflammatory Adenosine A2A Receptors In iNKT Cells Of Sickle Cell Patients During Vaso-Occlusive Episodes and Upon Activation Of Cultured Human iNKT Cells". Blood 122, № 21 (2013): 975. http://dx.doi.org/10.1182/blood.v122.21.975.975.
Full textSchneidawind, Dominik, Antonio Pierini, Maite Alvarez, et al. "CD4+ Invariant Natural Killer T Cells Require NKG2D To Protect From Lethal Acute Graft-Versus-Host Disease." Blood 122, no. 21 (2013): 898. http://dx.doi.org/10.1182/blood.v122.21.898.898.
Full textYigit, Burcu, Darrian Moskowitz, Xavier Michelet, Antoine Tanne, and Marc Van Dijk. "205 AgenT-797, a native allogeneic ‘off-the-shelf’ iNKT cell therapy product shows anti-tumor activity in preclinical xenograft models." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (2021): A216. http://dx.doi.org/10.1136/jitc-2021-sitc2021.205.
Full textSmyk, Daniel S., Athanasios Mavropoulos, Giorgina Mieli-Vergani, Diego Vergani, Marco Lenzi, and Dimitrios P. Bogdanos. "The Role of Invariant NKT in Autoimmune Liver Disease: Can Vitamin D Act as an Immunomodulator?" Canadian Journal of Gastroenterology and Hepatology 2018 (June 26, 2018): 1–14. http://dx.doi.org/10.1155/2018/8197937.
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