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Journal articles on the topic 'Innate groups of people'

Author: Grafiati

Published: 27 July 2024

Last updated: 31 July 2025

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1

Clohosey, Matthew L., Brendan T. Mann, Paul L. Ryan та ін. "Comparable Vδ2 Cell Functional Characteristics in Virally Suppressed People Living with HIV and Uninfected Individuals". Cells 9, № 12 (2020): 2568. http://dx.doi.org/10.3390/cells9122568.

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Crosstalk between innate and adaptive pathways is a critical component to developing an effective, lasting immune response. Among natural effector cells, innate-like γδ T cells promote immunity by facilitating communication between the two compartments and exerting cytotoxic effector functions. Dysregulation of γδ T cell populations is a byproduct of primary Humanimmunodeficiency virus (HIV) infection. This is most pronounced in the depletion and loss of function within cells expressing a Vγ9Vδ2 TCR (Vδ2 cells). Whether or not prolonged viral suppression mediated by antiretroviral therapy (ART

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Galgiani, John N., Amy P. Hsu, Daniel A. Powell, Jatin M. Vyas, and Steven M. Holland. "Genetic and Other Determinants for the Severity of Coccidioidomycosis: A Clinician’s Perspective." Journal of Fungi 9, no. 5 (2023): 554. http://dx.doi.org/10.3390/jof9050554.

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The endemic fungal infection, coccidioidomycosis, occurs after inhalation of one or very few Coccidioides spp. spores. Infections produce diverse clinical manifestations, ranging from insignificant to extremely destructive, even fatal. Approaches to understanding this range of consequences have traditionally categorized patients into a small number of groups (asymptomatic, uncomplicated self-limited, fibro-cavitary, and extra-thoracic disseminated) and then looked for immunologic differences among them. Recently, variants within genes of innate pathways have been found to account, in part, for

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Bellanti, Francesco, Aurelio Lo Buglio, Stefano Quiete, et al. "Sarcopenia Is Associated with Changes in Circulating Markers of Antioxidant/Oxidant Balance and Innate Immune Response." Antioxidants 12, no. 11 (2023): 1992. http://dx.doi.org/10.3390/antiox12111992.

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(1) Background: The involvement of redox balance alterations and innate immunity is suggested to play a key role in the pathogenesis of sarcopenia. This investigation aimed to define and relate modifications in circulating markers of redox homeostasis and the innate immune response in human sarcopenia. (2) Methods: A total of 32 subjects aged >65 years old and affected by sarcopenia according to the second “European Working Group on sarcopenia in older people” guidelines were compared with 40 non-sarcopenic age-matched controls. To assess systemic redox homeostasis, reduced (GSH) and oxidiz

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Khasanova, E. M., V. V. Grechenko, T. V. Gromova, S. A. Skhodova, and L. V. Gankovskaya. "Alterations in expression of TLR2 and TLR4 during successful and pathological aging." Russian Journal of Immunology 27, no. 4 (2024): 1107–14. http://dx.doi.org/10.46235/1028-7221-16733-aie.

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The generally accepted theory of aging is the theory of inflammaging. The leading role in its development is played by the mechanisms of innate immunity. Key receptors of innate immunity are TLRs. The patterns of age-related changes in the functioning of the TLR system remain the subject of study. The purpose of the work is to study the expression of TLR2 and TLR4 receptors in peripheral blood cells of centenarians and elderly people at the level of genes and surface molecules. The study analyzed the expression of genes and molecules TLR2 and TLR4 in young donors (n = 50), elderly people (n =

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Klein, Peter G., and J. Bruce Bullock. "Can Entrepreneurship Be Taught?" Journal of Agricultural and Applied Economics 38, no. 2 (2006): 429–39. http://dx.doi.org/10.1017/s107407080002246x.

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Is entrepreneurship an innate ability or an acquired skill? Can entrepreneurial acumen be achieved and enhanced through education and training, or are certain people “born” to be entrepreneurs or to act entrepreneurially? Economists and management theorists give widely divergent answers to these questions. This paper reviews the major approaches to teaching entrepreneurship, primarily at the undergraduate level, and relates them to economic theories of entrepreneurship. Surprisingly, we find little connection between the leading approaches to entrepreneurship education and economists' understa

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Bozhchenko, Alexander, and Vitaliy Yakushev. "FINGERPRINT MARKERS OF DELINQUENCY IN THE GROUP OF SERIAL KILLERS AND SUICIDES." Chronos 7, no. 10(72) (2022): 109–11. http://dx.doi.org/10.52013/2658-7556-72-10-31.

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The article is devoted to a comparative analysis of a number of combinations of types of papillary finger patterns, most characteristic of a group of serial killers and a group of suicides. It is established that combinatorics is most characteristic for both groups, in which the sum of the pattern codes of the index and middle fingers is equal to the value of the pattern code of the ring finger (right hand). The frequency of its occurrence in both comparison groups is 10%, which is about 10 times more frequent than in the control. Considering that papillary patterns are innate signs, the commo

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Shrwani, Khalid, Nabil Dhayhi, Waleed Mahallawi, et al. "The Protective Mechanism Against COVID-19, Antibody vs Cellular Immunity: An Extensive Review." International Journal of Innovative Research in Medical Science 8, no. 08 (2023): 300–307. http://dx.doi.org/10.23958/ijirms/vol08-i08/1721.

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The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a significant threat to the world, causing a respiratory illness with a wide range of symptoms and affecting people of all sexes and age groups. Although the innate immune response to SARS-CoV-2 is not entirely understood, recent findings suggest that a high number of innate immune cells and inflammatory cytokines can help in fighting the virus. However, an excessive expression of cytokines can lead to a cytokine storm, resulting in a severe disease state with high morbidity and mortality. The coordinated a

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Dellino, Miriam, Eliano Cascardi, Marina Vinciguerra, et al. "Nutrition as Personalized Medicine against SARS-CoV-2 Infections: Clinical and Oncological Options with a Specific Female Groups Overview." International Journal of Molecular Sciences 23, no. 16 (2022): 9136. http://dx.doi.org/10.3390/ijms23169136.

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Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It is acknowledged that vulnerable people can suffer from mortal complications of COVID-19. Therefore, strengthening the immune system particularly in the most fragile people could help to protect them from infection. First, general nutritional status and food consumption patterns of everyone affect the effectiveness of each immune system. The effects of nutrition could impact the level of intestinal and genital microbiota, the adaptive immune system, and the inn

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Herrera, Mariana, Yoav Keynan, Paul J. McLaren, et al. "Gene expression profiling identifies candidate biomarkers for new latent tuberculosis infections. A cohort study." PLOS ONE 17, no. 9 (2022): e0274257. http://dx.doi.org/10.1371/journal.pone.0274257.

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Objective To determine the gene expression profile in individuals with new latent tuberculosis infection (LTBI), and to compare them with people with active tuberculosis (TB) and those exposed to TB but not infected. Design A prospective cohort study. Recruitment and follow-up were conducted between September 2016 to December 2018. Gene expression and data processing and analysis from April 2019 to April 2021. Setting Two male Colombian prisons. Participants 15 new tuberculin skin test (TST) converters (negative TST at baseline that became positive during follow-up), 11 people that continued w

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Cronshaw, Steven F. "Developmental Dynamics of Workplace Adaptive Skill." Psychological Reports 96, no. 3_suppl (2005): 1066–94. http://dx.doi.org/10.2466/pr0.96.3c.1066-1094.

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This study examined the dynamic development of workplace adaptive skills using the functional-perspectivist paradigm. Extensions to a model of behavioral functionality are tested whereby workers in four age groups are assessed through an interview-based methodology on the improvement and coalescence of their adaptive skills. Analysis of responses show the dynamic structure of workplace adaptive skills changes over the age groups. Workers in their 20s face the developmental task of resolving tensions between their inward- and outward-directed focus. Workers in their 30s must equalize the opposi

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Melnikov, Oleg, Diana Zabolotnaya, Alexander Bredun, et al. "Humoral factors of innate immunity in the saliva of patients with infectious inflammatory respiratory diseases." OTORHINOLARYNGOLOGY, no. 2(1) 2018 (June 11, 2018): 13–17. http://dx.doi.org/10.37219/2528-8253-2018-2-13.

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Introduction: In recently ears factors of innate immunity both cellular and humoral have been paid considerable attention as they are a protective barrier of a fast response and that is why they are largely concentrated at the intersection of the digestive tract and airways. The data concerning the activity level of factors of innate immunity in the upper airways affected by nonspecific inflammatory processes is insufficient and sparse and therefore the purpose of this research was to study the content of humoral factors of innate immunity in the oropharyngeal secretion (ORS) of patients with

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Zahir, Brwa, Kaniaw Khafar, and Mariwan Hama Salih. "Alterations in some Physiological and Inflammatory Markers in Iron-Deficient Obese Adults in the Kurdistan Region, Iraq." AL-Kindy College Medical Journal 18, no. 3 (2022): 233–36. http://dx.doi.org/10.47723/kcmj.v18i3.883.

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Background: Iron homeostasis is crucial to many physiological functions in the human body, such as cellular activity, erythropoiesis, and the innate immune response. Iron deficiency anemia may occur from obesity's ability to disturb iron homeostasis. Obesity may be seen as a pre-inflammatory condition with mild, ongoing systemic inflammation. Additionally, an increase in hepcidin levels by chronic inflammation causes iron insufficiency in obese people. For this reason, this current experiment is designed to investigate the iron profile and some hematological and inflammatory parameters in obes

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Shlyk, I. F., L. P. Sizyakina, R. V. Sidorov, and S. V. Shlyk. "Functional features of innate immunity in the development of postpericardiotomy syndrome in patients after coronary artery bypass grafting." Medical Herald of the South of Russia 10, no. 4 (2019): 71–79. http://dx.doi.org/10.21886/2219-8075-2019-10-4-71-79.

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Objective: to study the functional characteristics of innate immunity in the formation of postpericardial syndrome (PPS) in patients undergoing coronary artery bypass graft ing (CABG).Materials and methods: the study involved 60 people, 40 of them made up the main group of patients with coronary artery disease, which retrospectively aft er 1 month of observation was divided into 2 groups. Group I CABG and PPS, group II CABG without PPS. The control group consisted of 20 patients without IHD. Before surgery, aft er 5, 14 days and 1 month, the expression of toll-like receptors (TLRs) 2, 4, 9, th

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Kodintseva, Е. А., and А. А. Akleyev. "Delayed correlated parameters of adaptive and innate immunity in chronically irradiated subjects." Russian Journal of Immunology 23, no. 2 (2020): 225–30. http://dx.doi.org/10.46235/1028-7221-399-dcp.

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Radiation-induced changes in the immune system develop quite early after the onset of radiation exposure and persist over a long time after it's removal. In case of chronic radiation exposure at dose rate lower than 0.1 Gy/year, the threshold of annual dose to suppress red bone marrow hemato- and immunopoiesis reaches 0.3-0.5 Gy. It was shown that adaptation mechanisms are triggered under the chronic impact of ionizing radiation in the hematopoietic system. In our study we quantitatively and qualitatively analyzed relationships between individual arms of the immune system which is important fo

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Mikhalev, Maxim. "Khalifa of Pamir, Custodians of Knowledge." MEΘEXIS Journal of Research in Values and Spirituality V, no. I (2025): 104–14. https://doi.org/10.71210/mjrvs.8.a.5.

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This paper explores both social role and spiritual functions of the local religious leaders in Tajikistan sector of Pamir mountains, called Gorno-Badakshan Autonomous Oblast. This remote and isolated mountainous region is criss-crossed by the state borders of China, Pakistan, Afghanistan and Tajikistan and serves as the abode for several obscure ethnic groups that since long have adopted Ismailism, an esoteric branch of Shia Islam. The leader of Ismaili Aga Khan IV helped local people to survive horrors of civil war that ravaged this region in the 1990s, and now effectively administer Gorno-Ba

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Pramudya, Manikya, and Sri Puji Astuti Wahyuningsih. "Immunomodulatory potential of polysaccharides from Coriolus versicolor against intracellular bacteria Neisseria gonorrhoeae." Veterinary World 12, no. 6 (2019): 735–39. http://dx.doi.org/10.14202/vetworld.2019.735-739.

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Background and Aim: For many years, people use natural products from the plant and fungal to improve immune response against microorganism. This study aimed to investigate the immunomodulatory properties of polysaccharides (PS) from Coriolus versicolor in mice infected by intracellular bacteria Neisseria gonorrhoeae. Materials and Methods: Thirty-six female BALB/C mice were divided into six groups: Normal control, negative control, positive control, P1 (PS before infection), P2 (PS after infection), and P3 (PS before and after infection). PS were administrated for 10 days. N. gonorrhoeae was i

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Rennebohm, Robert M. "What is the current status of the covid pandemic? What can/should we do at this point?" Pediatrician (St. Petersburg) 14, no. 1 (2023): 89–98. http://dx.doi.org/10.17816/ped14189-98.

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As a direct result of the mass vaccination campaign against COVID (in all age groups), humanity is likely to face a threatening situation that could potentially become catastrophic. The mass vaccination campaign has caused multiple increasingly contagious dominant variants of the SARS-CoV-2 virus. The reason is the phenomenon of immune escape, neutralizing antibodies induced by the vaccine quickly cease their function, and vaccine non-neutralizing antibodies can make the virus more contagious a form of antibody-mediated or antibody dependent amplification of the infection. Thus, an

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Alzouabi, Lina. "Social Environment and Crime in Dickens' Oliver Twist and Great Expectations." International Journal of Linguistics, Literature and Translation 4, no. 6 (2021): 163–70. http://dx.doi.org/10.32996/ijllt.2021.4.6.19.

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This study reads Charles Dickens' Oliver Twist and Great Expectations as crime novels by applying Sutherland's theory of "differential association" which postulates that criminal behavior is learned rather than inherited, and it is learned through interaction with other people within intimate personal groups in which one learns techniques and acquires motives for committing crimes. In Oliver Twist, Oliver is portrayed as a victim of the corrupted social environment as well as Monks' conspiracy with Fagin to drag him down to the underworld.; he is raised as an orphan in a workhouse and subjecte

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Kozlov, Evgenii M., Ekaterina Ivanova, Andrey V. Grechko, Wei-Kai Wu, Antonina V. Starodubova, and Alexander N. Orekhov. "Involvement of Oxidative Stress and the Innate Immune System in SARS-CoV-2 Infection." Diseases 9, no. 1 (2021): 17. http://dx.doi.org/10.3390/diseases9010017.

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The emergence of the novel coronavirus in December 2019 in China marked the beginning of a pandemic that impacted healthcare systems and economic life all over the world. The virus primarily targets the respiratory system causing severe acute respiratory syndrome (SARS) in some patients, and therefore received the name of SARS-CoV-2. The pathogen stands out among other coronaviruses by its rapid transmission from human to human, with the majority of infected individuals being asymptomatic or presenting with only minor illness, therefore facilitating the pathogen spread. At the same time, peopl

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Pitt, Benjamin, Stephen Ferrigno, Jessica F. Cantlon, Daniel Casasanto, Edward Gibson, and Steven T. Piantadosi. "Spatial concepts of number, size, and time in an indigenous culture." Science Advances 7, no. 33 (2021): eabg4141. http://dx.doi.org/10.1126/sciadv.abg4141.

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In industrialized groups, adults implicitly map numbers, time, and size onto space according to cultural practices like reading and counting (e.g., from left to right). Here, we tested the mental mappings of the Tsimane’, an indigenous population with few such cultural practices. Tsimane’ adults spatially arranged number, size, and time stimuli according to their relative magnitudes but showed no directional bias for any domain on any spatial axis; different mappings went in different directions, even in the same participant. These findings challenge claims that people have an innate left-to-r

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Cook, Elina K., Richard N. Armstrong, Eshita Sharma, et al. "RNA-Seq Analysis of Clonal Hematopoiesis (CHIP) Blood Leukocytes Shows Dysregulation of Neutrophil / Innate Immunity-Related Genes." Blood 132, Supplement 1 (2018): 3843. http://dx.doi.org/10.1182/blood-2018-99-116128.

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Abstract BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) involves the peripheral blood (PB) expansion of progeny of a hematopoietic stem or progenitor cell that is somatically mutated in a hematological cancer-associated gene (most often TET2 or DNMT3A). CHIP associates with comorbid diseases of aging such as cardiovascular disease. Murine knockout (Tet2 or Dnmt3a) and engraftment models of CHIP develop exacerbated cardiovascular disease and their mutated myeloid cells are more reactive to inflammatory stimuli. However, whether blood leukocytes in human CHIP are hyper-inflam

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Gankovskaya, L. V., and O. V. Artemyeva. "Role of innate immunity mechanisms in the development of normal and pathological aging." Problems of Geroscience, no. 4 (February 20, 2025): 192–95. https://doi.org/10.37586/2949-4745-4-2024-192-195.

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BACKGROUND.One of the key indicators of immunosenescence is inflammatory aging (inflammaging), which is primarily attributed to the mechanisms of innate immunity. The assumed cause of inflammaging is chronic activation of patternrecognizing receptors of the innate immunity and their signaling pathways by endogenous and exogenous danger signals. The major role in this process is held by Toll-like receptors (TLR) and NOD-like receptors (NLR). Their activation triggers the implementation of effector mechanisms of innate immune defense; in the context of aging, this contributes to the development

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Naji, Amel A., and Hind M. Mousa. "The Sera levels of Interleukin-13 in Patients with Atopic Dermatitis in Thi-Qar province." University of Thi-Qar Journal of Science 9, no. 1 (2022): 39–42. http://dx.doi.org/10.32792/utq/utjsci.v9i1.874.

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The Interleukin-13 (IL-13) is a component of the innate immune system that is primarily produced by Th2 cells and is found in high concentrations in skin lesions of atopic dermatitis. The study comprised 90 people of both genders, 45 of whom were patients who attending to Al-Nassirya teaching Hospital, Dermatology, during a period between November 2021 to March 2022, and the same number served as controls. Blood samples were obtained from both groups, and the serum levels of IL-13 were estimated using an ELISA-ready kit.The findings of the current study referred that young adult, and the femal

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Epstein, Larissa, Jamie L. Peyton, Alexandra Coward, et al. "97 Animals Are People Too: Comparing Human and Animal Burns in a Large Wildfire." Journal of Burn Care & Research 45, Supplement_1 (2024): 78. http://dx.doi.org/10.1093/jbcr/irae036.096.

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Abstract Introduction Although human burns have been studied in depth, there are few studies involving animal burns, and even fewer studies that compare the two. However, recent wildfires across the globe, like the 2019 Australian bushfire, have drawn attention to the plight of animals. Our study aims to compare effects of wildfire burns between humans and animals. Animals have adaptations that may protect them from burns: fur/feathers, agility, innate fight or flight response, and burrowing/swimming/flying abilities. We hypothesize that humans would have deeper burns and a higher mortality ra

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Butusov, Alexander M., Olga V. Krusko, Petr K. Potapov, et al. "Polymorphisms of leukocyte genes human and congenital antigen immunity associated with different the severity of the course of the new coronavirus infections." Bulletin of the Russian Military Medical Academy 24, no. 3 (2022): 547–56. http://dx.doi.org/10.17816/brmma108133.

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The most significant single nucleotide human leukocyte antigen genes polymorphisms and innate immunity genes associated with varying degrees of acute respiratory infection severity are consideredCOVID-19 caused by the SARS-CoV-2 coronavirus. As data accumulated, it became clear that the SARS-CoV-2 virus exhibits significant regional, ethnic, and individual specificity. This is due to the population groups genetic characteristics. This is necessary to reliably know the human genotype relationship with the COVID-19 course severity (asymptomatic, mild, moderate, severe, and extremely severe up to

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Witkowski, Jacek M., and Ewa Bryl. "Mechanizmy COVID-19 a układ odpornościowy i jego starzenie." Kosmos 70, no. 3 (2021): 407–17. http://dx.doi.org/10.36921/kos.2021_2819.

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Epidemiological studies concerning the new coronavirus disease called COVID-19 show that elderly and old people are more susceptible to symptomatic, severe course of the disease, and also to death as its consequence. These age groups frequently suffer from associated, aging-related, chronic inflammatory diseases, in the case of COVID-19 described as co-morbidities. This paper describes the mechanisms of infection by SARS-CoV-2 virus and the development of acute COVID-19 and of its chronic form called long COVID, as well as the participation of various components of the immune system in the dev

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Roberts, Jennifer R., and Molly Maxfield. "Mortality Salience and Age Effects on Charitable Donations." American Behavioral Scientist 63, no. 14 (2019): 1863–84. http://dx.doi.org/10.1177/0002764219850864.

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Research suggests that people are typically more generous in later life. Terror management theory offers one explanation for this pattern. The theory suggests that humans’ innate desire to survive results in strong reactions to increased awareness of mortality, thereby affecting behaviors. Older adults’ increasing proximity to life’s end has been associated with greater generative concern, as a means of caring for future generations and ensuring symbolic immortality. This experimental study evaluated the effects of age and mortality salience on charitable giving. Age and mortality salience int

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Heldisari, Hana Permata. "Musical Ability and Interpersonal Intelligence in The Late Childhood Period." Gondang: Jurnal Seni dan Budaya 4, no. 2 (2020): 185. http://dx.doi.org/10.24114/gondang.v4i2.18867.

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Learning to adjust to peers and develop attitudes towards social groups and institutions is one of the developmental tasks of late childhood. Musical abilities present as innate and function since childhood.Associated with two things namely interpersonal intelligence and musical abilities, both are being developed in late childhood. This study aims to determine whether there is a relationship between musical ability and interpersonal intelligence in the late childhood period. This research uses quantitative research method with the type of correlation. The population of this research was all s

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Mudassar Hussain and Naeem Akhtar. "Theoretically Justification of Human Rights: A Case of Natural Rights Theory." Zakariya Journal of Social Science 2, no. 1 (2023): 42–53. http://dx.doi.org/10.59075/zjss.v2i1.232.

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The theoretical justification of natural rights examines the philosophical foundations and ethical principles that support the existence and applicability of these rights. People have some rights simply by being human, and neither groups nor governments may bestow them upon them, according to the idea of natural rights. It also provides a concise overview of the theories that support natural rights, including those that rely on moral intuition, human nature, and the Social Contract. The moral intuition approach maintains that natural rights are self-evident and universally accepted since they

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Duan, Yongzhong, Jieyuan Zeng, Shengtao Fan, et al. "Herpes Simplex Virus Type 1–Encoded miR-H2-3p Manipulates Cytosolic DNA–Stimulated Antiviral Innate Immune Response by Targeting DDX41." Viruses 11, no. 8 (2019): 756. http://dx.doi.org/10.3390/v11080756.

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Herpes simplex virus type 1 (HSV-1), one of the human pathogens widely epidemic and transmitted among various groups of people in the world, often causes symptoms known as oral herpes or lifelong asymptomatic infection. HSV-1 employs many sophisticated strategies to escape host antiviral immune response based on its multiple coding proteins. However, the functions involved in the immune evasion of miRNAs encoded by HSV-1 during lytic (productive) infection remain poorly studied. Dual-luciferase reporter gene assay and bioinformatics revealed that Asp-Glu-Ala-Asp (DEAD)-box helicase 41 (DDX41),

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Radwan, Ghada Abd Eltawab, Ali El-Said Yousef, and Mohamed Fathy Bayomy. "Serum interleukin 18 level in kidney diseases and age." Urology Annals 16, no. 2 (2024): 133–39. http://dx.doi.org/10.4103/ua.ua_140_22.

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Background: Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene, it is a member of the IL 1 family and has a molecular weight of 18 kDa. Innate and adaptive immunity can be regulated by IL-18, and disorders involving its dysregulation might result in inflammatory or autoimmune conditions. Aim of the Work: To distinguish between acute kidney injury (AKI) and chronic renal failure (CRF), this research investigates the utility of IL-18 as a novel biomarker and examines how age affects its level. Materials and Methods: Thr

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SON, G. Kentak. "Cultural Race and an Inclusive Nationalism Sun Yat-sen’s (1866-1925) Nationalism during China’s Modernization." Cultura 17, no. 2 (2020): 165–80. http://dx.doi.org/10.3726/cul022020.0013.

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Abstract: Sun Yat-Sen was a Chinese philosopher and politician, who served as the provisional first president of the Republic of China, and first leader of the Kuomintang (Nationalist Party of China). He argued that common blood, language, customs, religion and livelihood were the five essential elements that constituted a nation. Sun was influenced by social Darwinism in his understanding that sociocultural forces could override the innate characteristics of race. Thus, he employed racially defined nationalism by invoking anti-Manchuism. Although China’s modernisation in the first decades of

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Urazmambetov, R. T., S. A. Chebotov, and T. V. Loboda. "Features of both immune and psycho-emotional factors in the adaptive reactions of first-year students." Medical Herald of the South of Russia 14, no. 4 (2023): 29–34. http://dx.doi.org/10.21886/2219-8075-2023-14-4-29-34.

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Objective: comparative characteristics of indicators of psycho-emotional and immune statuses of first-year students in various conditions of the educational process.Materials and methods: 2nd groups of first-year students of Rostov State Medical University from the medical and preventive faculty (18 people) and the military training center (17 people) were examined. They were all comparable in age (19 ±1 and 19±2 years), gender (all men), physical condition (corresponded to the I-st health group). The immune status was assessed at the Research Institute of Clinical Immunology using standard me

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Melikhov, Aleksandr Ivanovich. "National security in the light of the organic theory of the State." Вопросы безопасности, no. 3 (March 2022): 79–92. http://dx.doi.org/10.25136/2409-7543.2022.3.38550.

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The article examines the phenomenon of national security through the prism of the organic theory of state and law. According to the author, national security is a projection of a person's vital needs for self-preservation, self-maintenance and self-reproduction of the multinational people of Russia. The novelty of this statement lies in the expansion of the traditional approach to the concept of security by the needs of self-maintenance and self-reproduction. The object of ensuring national security is the multinational people of the Russian Federation, which currently exists in the form of an

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Martín-Cardona, Albert, Anna Carrasco, Carme Ferrer, et al. "Histology of the Upper Gastrointestinal Tract, Morphometry and Lymphocyte Subpopulations of the Duodenal Mucosa: Insights from Healthy Individuals." International Journal of Molecular Sciences 26, no. 3 (2025): 1349. https://doi.org/10.3390/ijms26031349.

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The upper oesophagogastrointestinal (UEGI) tract histology, intestinal morphometry and lymphocyte subpopulations of healthy people is scarcely known. In research studies of inflammation involving the UEGI tract, there is a lack of adequate healthy controls. Aims: To evaluate the histology of the UEGI tract and the duodenal lymphocyte subpopulations of healthy volunteers and patients with gastroesophageal reflux disease (GERD), the latter to assess if it could replace healthy subjects. Healthy individuals were excluded if they had symptoms, comorbidities, pregnancy, toxics, medications or abnor

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Kuna, Anna, and Anna Katarzyna Wrońska. "Minerals and their role in the optimal functioning of the immune system – literature review." Polish Journal of Sports Medicine 39, no. 3 (2023): 95–104. http://dx.doi.org/10.5604/01.3001.0053.8765.

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An adequate supply of minerals in the diet is crucial for the proper functioning of the immune system. This applies to both the mechanisms of innate and adaptive immunity, and in particular, the pro- and anti-inflammatory balance of the body. For most people, a balanced diet is sufficient to provide the body with adequate amounts of minerals. However, certain groups are particularly at risk of deficiencies in these nutrients. These include people who perform frequent and intense sports training when the body does not have an opportunity to regenerate properly. The aim of this paper was to disc

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Cofnas, Nathan. "The Anti-Jewish Narrative." Philosophia 49, no. 4 (2021): 1329–44. http://dx.doi.org/10.1007/s11406-021-00322-w.

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AbstractAccording to the mainstream narrative about race, all groups have the same innate dispositions and potential, and all disparities—at least those favoring whites—are due to past or present racism. Some people who reject this narrative gravitate toward an alternative, anti-Jewish narrative, which sees recent history in terms of a Jewish/gentile conflict. The most sophisticated promoter of the anti-Jewish narrative is the evolutionary psychologist Kevin MacDonald. MacDonald argues that Jews have a suite of genetic adaptations—including high intelligence and ethnocentrism—and cultural prac

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Martens, Pieter-Jan, Conny Gysemans, and Chantal Mathieu. "100 YEARS OF INSULIN: Arresting or curing type 1 diabetes: an elusive goal, but closing the gap." Journal of Endocrinology 249, no. 2 (2021): T1—T11. http://dx.doi.org/10.1530/joe-20-0552.

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Type 1 diabetes is one of the most common chronic diseases in children and adolescents, but remains unpreventable and incurable. The discovery of insulin, already 100 years ago, embodied a lifesaver for people with type 1 diabetes as it allowed the replacement of all functions of the beta cell. Nevertheless, despite all technological advances, the majority of type 1 diabetic patients fail to reach the recommended target HbA1c levels. The disease-associated complications remain the true burden of affected individuals and necessitate the search for disease prevention and reversal. The recognitio

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Vakili, Poya, Shahed Meshgini, Fatemeh Jalilian, Ilgar Amjadi, Mobina Belalzadeh, and Mina Deljavan Ghodrati. "The Effect of Sericin on Heat Shock Proteins 60 and 90, and TLR2 and TLR4 Induced by Chronic Heat Stress in Male Mice." Biomedical Research Bulletin 1, no. 2 (2023): 48–52. http://dx.doi.org/10.34172/biomedrb.2023.10.

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Background: Heat stress followed by heat stroke, which is caused by an increase in body temperature to more than 40 °C, is a medical emergency that affects many people in work situations and weather conditions and results in irreversible neurological and cognitive damage. Methods: In general, 75 male albino mice in the weight range of 28-30 g were used in the present study. The mice were divided into 5 groups of 15, including the control group, heat stress (HS) group, HS group+sericin 100, HS group+sericin 150, and HS group+sericin 200. Toll-like receptor 2 (TLR2) and Toll-like receptor (TLR4)

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Najafova, Lamiya. "SYSTEMATİZATİON OF KNOWLEDGE BY MEANS OF A MAP DURİNG TEACHİNG." Deutsche internationale Zeitschrift für zeitgenössische Wissenschaft 80 (May 17, 2024): 20–21. https://doi.org/10.5281/zenodo.11211861.

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This article explores the integration of maps as effective tools for systematizing knowledge in an educational context. Drawing from cognitive psychology and educational theory, he explores the role of visuospatial representation in enhancing learning outcomes and building deeper understanding among students. A theoretical basis for the organization and search of knowledge has been created, emphasizing the natural tendency of people to organize information spatially. This innate cognitive process is harnessed across different subjects and age groups through different types of maps, includ

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Koufakis, Theocharis, Dimitrios Kouroupis, Georgios Dimakopoulos, et al. "Circulating Beta-Defensin 2 Levels Correlate with Conventional Inflammatory Markers in Infection-Free Individuals with Overweight and Obesity: An Exploratory Study." Biomedicines 13, no. 8 (2025): 1800. https://doi.org/10.3390/biomedicines13081800.

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Background/Objectives: The role of intestinal dysbiosis as an important driver of inflammation in metabolic disorders is becoming increasingly evident. Beta-defensin 2 is an antimicrobial peptide that contributes to innate immunity, while recently it has been suggested as a novel biomarker of gut dysbiosis. However, its role in obesity remains unexplored. This study aimed to compare circulating beta-defensin 2 levels between individuals with overweight and obesity and lean controls. An additional objective was to explore potential correlations between beta-defensin 2 and other inflammatory mar

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Ma, Yangyang. "Rational Exploration of Compassion Education." Journal of Higher Education Teaching 1, no. 3 (2024): 81–86. http://dx.doi.org/10.62517/jhet.202415312.

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With the rapid development of modern industry in China, people's lifestyle and quality of life have been significantly improved compared with the past. The strong appeal of social groups for a better life and strengthening the construction of spiritual civilization has become the vane to guide the new development of society. However, with the rapid development of social material civilization, people's spiritual civilization construction is becoming increasingly backward, especially the lack of compassion development of adolescent groups. Compassion is the true expression of human nature. It no

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Barlow, Helen. "‘Praise the Lord! We are a Musical Nation’: The Welsh Working Classes and Religious Singing." Nineteenth-Century Music Review 17, no. 3 (2020): 445–72. http://dx.doi.org/10.1017/s1479409819000570.

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The title quotation from Under Milk Wood encapsulates a widely held belief in the innate musicality of the Welsh and its religious roots. These roots were put down deeply during the nineteenth century, in a huge expansion of choral and congregational singing across Wales and particularly in the industrial communities. This development has been described as ‘a democratic popular choral culture rooted in the lives of ordinary people’, and central to it was the cymanfa ganu, the mass hymn-singing festival. Choral and congregational singing, typified by the cymanfa ganu, underpinned the perception

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Mittal, Shruti, Mamata Mahapatra, and Shadab Ahamad Ansari. "Effect of Art Therapy on Adolescents’ Mental Health." Российский психологический журнал 19, no. 4 (2022): 71–79. http://dx.doi.org/10.21702/rpj.2022.4.4.

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Introduction. Adolescent children continue to be vulnerable to issues of mental health. A significant population of these groups suffers from peer pressure, depression, anxiety and parental pressure. Many adolescent people fail to express their emotions to other people. As a result, they experience low self-esteem, fail to communicate effectively and sometimes even fail to appreciate their personalities. Theoretical Basis. A research study that employs the systematic review follows formulated questions. In this research, the formulated question guides understanding the relevance of studies in

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Jayarathne, Avanthi, and W. D. Chandrasena. "INVESTIGATION OF THE EFFECTIVENESS OF USING SELF-DETERMINATION THEORY IN TEACHING SCIENCE FOR GRADE EIGHT STUDENTS: A CASE STUDY IN SRI LANKA." International Journal of Research -GRANTHAALAYAH 7, no. 4 (2020): 126–31. http://dx.doi.org/10.29121/granthaalayah.v7.i4.2019.881.

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Science is highly important as it focusses on enhancing the quality of human life. Though, science is perceived to be an interesting discipline, students’ performance in the field of school science is not very satisfactory. Self-determination theory (SDT) assumes that inherent in human nature is the propensity to be curious about one’s environment and interested in learning and developing one’s knowledge. Thus, SDT can be used to teach science effectively in classrooms to enhance students’ performance. As described in SDT, people have three innate psychological needs; competence, autonomy and

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Rončević, Tomislav, Jasna Puizina, and Alessandro Tossi. "Antimicrobial Peptides as Anti-Infective Agents in Pre-Post-Antibiotic Era?" International Journal of Molecular Sciences 20, no. 22 (2019): 5713. http://dx.doi.org/10.3390/ijms20225713.

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Resistance to antibiotics is one of the main current threats to human health and every year multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a result. Ever since their discovery, some 40 years ago, the antimicrobial peptides (AMPs) of innate defense have been hailed as a potential alternative to conventional antibiotics due to their relatively low potential to elicit resistance. Despite continued effort by both academia and start-ups, currently there are still no antibiotics based on AMPs in use. In this study, we discuss what we know and what we do

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Sumantri, Stevent, and Iris Rengganis. "Immunological dysfunction and mast cell activation syndrome in long COVID." Asia Pacific Allergy 13, no. 1 (2023): 50–53. http://dx.doi.org/10.5415/apallergy.0000000000000022.

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At least 65 million people around the world suffer from long COVID-19, with the majority of cases occurring in the productive age (36–50 years old). Individuals with long COVID-19 are confounded with multiple organ system dysfunctions, long-term organ injury sequelae, and a decreased quality of life. There is an overlapping of risk factors between long COVID-19 and other postviral infection syndromes, so advances in research could also benefit other groups of patients. Long COVID-19 is the consequence of multiple immune system dysregulation, such as T-cell depletion, innate immune cell hyperac

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Wai, Zubairu. "Rethinking War and Violence in Sierra Leone: The RUF and the Nature and Condition of Insurgency Violence." African Conflict & Peacebuilding Review 13, no. 1 (2023): 44–76. http://dx.doi.org/10.2979/acp.2023.a900890.

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ABSTRACT: One of the most perplexing contradictions of the Sierra Leonean civil war was the disconnect between an insurgency movement that defined its project as an emancipatory program of national liberation and the large-scale violence, destructions, and brutalities it inflicted on the rural poor and other marginalized groups in the name of that project. A question that has thus continued to plague the war is why a movement that claimed to be fighting on behalf of the poor and marginalized also ended up committing horrific atrocities against the very people on whose behalf it claimed to be f

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Naiff, Priscilla, Selma Kuckelhaus, Shirley Couto, et al. "Phagocytic activity of monocytes and neutrophils in patients with periodontitis, whether or not associated to type 2 diabetes." Acta Odontológica Latinoamericana 34, no. 3 (2021): 201–13. http://dx.doi.org/10.54589/aol.34/3/201.

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Phagocytic functions by neutrophils/ monocytes and biochemical parameters were assessed in peripheral blood of patients with periodontitis, whether or not associated to type 2 diabetes, or patients with type 2 diabetes, or systemically healthy people. Fifty-eight participants were divided into four groups: Control – systemically and periodontally healthy patients (C, n=16), Periodontitis (P, n=14), Type 2 Diabetes (DM, n=11) and Periodontitis associated with type 2 diabetes (DMP, n=17). Blood samples were used to analyze phagocytic activity and the production of superoxide anion using optical

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Adnan Kadhem, Dhuha. "Evaluation Of NLRP3 Inflammasome Activity In Cardiovascular Diseases Patients In Najaf Governorate." Medical Science Journal for Advance Research 3, no. 4 (2022): 184–91. http://dx.doi.org/10.46966/msjar.v3i4.83.

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Background: The NLRP3 inflammasome is a crucial constituent of innate immunity, mediating caspase-1 stimulation and the production of pro-inflammatory cytokines Interleukin one and Interleukin-18. Still, abnormal activating of the NLRP3 inflammasome is being connected to a number of inflammatory diseases, such as diabetes, and atherosclerotic cardiovascular disease. Cardiovascular diseases are still widespread with significant deaths and morbidity ratios. Most CVDs are caused by vascular damage, including atherosclerosis, aneurysms, and subsequent ischemic heart conditions. Aim of the study: E

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