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1

Fim, Neto Arnaldo 1987. "Estudo da atividade contrátil do coração do inseto T. molitor : instrumentação e experimentação." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/259394.

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Orientadores: José Wilson Magalhães Bassani, Pedro Xavier de Oliveira<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Elétrica e de Computação<br>Made available in DSpace on 2018-08-21T21:15:04Z (GMT). No. of bitstreams: 1 FimNeto_Arnaldo_M.pdf: 1424780 bytes, checksum: 73cab0ac057a4075313d76ce8e26bbbf (MD5) Previous issue date: 2012<br>Resumo: O vaso dorsal de insetos tem sido proposto como um modelo mais simples para estudar o desempenho do coração em diferentes condições. O vaso dorsal apresenta características semelhantes às encontradas no coração d
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2

Martorana, M. G. "Vasodilator aspects of some cardiac inotropic agents." Thesis, University of Strathclyde, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.372098.

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3

Penna, Larissa Barretta. "Resposta inotropica a catecolaminas em miocitos ventriculares isolados de ratos submetidos a choque nas patas." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314789.

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Orientador: Rosana Almada Bassani<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-09T08:29:36Z (GMT). No. of bitstreams: 1 Penna_LarissaBarretta_M.pdf: 693702 bytes, checksum: 8dc2d8f7e3689a2bd6879211f15ccf07 (MD5) Previous issue date: 2007<br>Resumo: Tem sido descrita supersensibilidade ao efeito cronotrópico do isoproterenol (ISO) em átrios direitos de ratos submetidos a choque nas patas, mas há pouca informação com relação à resposta inotrópica, principalmente ventricular. O objetivo deste trabalho foi estudar os
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4

Axelsson, Birger. "Cardiac effects of non-adrenergic inotropic drugs : clinical and experimental studies." Doctoral thesis, Umeå universitet, Anestesiologi och intensivvård, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-68967.

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Background: Myocardial failure and dysfunction is not uncommon during critical illness and following cardiac surgery. For optimal treatment, a better understanding of the effects of inotropic drugs is needed. In this thesis, two non-adrenergic mediated inotropes, milrinone and levosimendan were studied in different models of myocardial dysfunction. The study aims were to assess the following: the effects of milrinone on blood flow in coronary artery bypass grafts during CABG surgery; the effects of milrinone on left ventricular diastolic function during post-ischaemic myocardial dysfunction; w
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5

Mielke, Marilyn. "Mechanisms underlying the inotropic response to angiotensin II in the heart." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325976.

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6

Fong, Yew Su. "Cardiac contractile actions of prostaglandin F₂α". Thesis, University of Bath, 1998. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242532.

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7

Thorstensen, Anders. "2D and 3D echocardiography during inotropic alterations and after recent myocardial infarction." Doctoral thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for sirkulasjon og bildediagnostikk, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-20011.

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Vurdering av venstre ventrikkels størrelse og funksjon er helt sentral ved enhver ekkokardiografisk undersøkelse og den vanligste kliniske indikasjon for å utføre ultralyd av hjertet. I dette prosjektet ble hjertefunksjonen hovedsakelig undersøkt ved hjelp av todimensjonal og tredimensjonal beregning av ejeksjonsfraksjon, hastighetsmålinger i hjertemuskelen ved hjelp av vevsdoppler, todimensjonal og tredimensjonal speckle tracking (mønsterfølging) og visuell vurdering av veggfortykkelse i gråtonebildet. Et viktig mål med prosjektet var å evaluere tradisjonelle og moderne ekkokardiografiske met
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8

Penny, Daniel James. "Changes in integrated cardiovascular physiology during inotropic stimulation in the early postnatal period." Monash University, Institute of Reproduction and Development, 2004. http://arrow.monash.edu.au/hdl/1959.1/9661.

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9

Everett, Scott D. "The Pharmacodynamics and Toxicodynamics of Inotropic Drugs in Calves With Natural and Artificial Hearts." DigitalCommons@USU, 1994. https://digitalcommons.usu.edu/etd/4103.

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Inotropic support for the failing myocardium as the therapy for xi congestive heart failure (CHF) is intended to achieve an increase in cardiac output via positive responses in myocardial contractility and vasodilation. A novel approach to differentiate these two responses is the use of an animal with an implanted total artificial heart (TAH). Three inotropic drugs, dobutamine, enoximone, and pimobendan, were tested in eight animals with their natural heart intact and five animals implanted with a TAH. Baseline values of the TAH and natural heart (NH) were compared to determine their hemodynam
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10

Governali, Serena. "Action mechanisms of physiological and pharmacological inotropic interventions on the slow/cardiac striated muscle." Doctoral thesis, Università di Siena, 2020. http://hdl.handle.net/11365/1107309.

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ACTION MECHANISMS OF PHYSIOLOGICAL AND PHARMACOLOGICAL INOTROPIC INTERVENTIONS ON THE SLOW/CARDIAC STRIATED MUSCLE. The mechanical performance of striated muscle is under the control of both thin and thick filament regulation. The start signal is the increase of intracellular Ca2+ concentration, promoted by cell membrane depolarization by the action potential, followed by Ca2+ binding to troponin in the thin filament and structural changes in the troponin–tropomyosin complex that release the actin sites for binding of myosin motors. The second regulatory mechanism, based on thick filament m
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11

Xiang, Hong. "Alpha₁-adrenoceptor-mediated phosphoinositide breakdown and inotropic responses in right ventricles of streptozotocin-diabetic rats." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/31036.

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The morbidity of and the mortality from cardiac disease are higher in diabetic patients. Clinical and experimental evidence suggests that diabetes-induced changes at the level of myocardium can, at least partially, contribute to these cardiac problems. The mechanism(s) involved in this diabetic cardiomyopathy is still unclear, but one defect appears to occur in the alpha₁-adrenoceptor system. Altered myocardial sensitivity and responsiveness to alpha₁-adrenoceptor agonists have been reported in experimental diabetes mellitus. Stimulation of alpha₁-adrenoceptors is known to produce a positive i
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12

Bell, David. "Receptors for positive inotropic peptides and associated mechanisms of contractile coupling in isolated ventricular cardiomyocytes." Thesis, Queen's University Belfast, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359022.

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13

Paskvalin, Mario. "Species differences in cardiovascular effects of a novel endogenous inotropic factor (EIF) isolated from porcine heart." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0026/NQ32886.pdf.

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14

Carvalho, George. "Studies on the inotropic effect of insulin and glucose : a new diet for the ischemic heart?" Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=101840.

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The present project investigated the effect of glucose, high dose insulin and normoglycemia (GIN) therapy in patients undergoing coronary revascularization surgery. A reduction in myocardial injury as measured by cardiac troponin I was the primary end point. Cardiac function based on hemodynamics and vasoactive drug requirements as well as clinical outcome were evaluated. Hormones and metabolites and cardiac metabolism were investigated concurrently as potential mechanisms of GIN therapy. The major findings of the present study are that GIN therapy reduced post-operative myocardial injury and
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15

Stangl, Verena. "Charakterisierung negativ inotroper Substanzen nach Myokardischämie." Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2002. http://dx.doi.org/10.18452/13803.

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Kardialen Strukturen, wie dem koronaren oder endokardialen Endothel, dem Myokard und auch dem Perikard werden unter physiologischen und pathophysiologischen Bedingungen zunehmend autokrine oder parakrine Funktionen zugesprochen. Es ist gut belegt, dass das Herz durch Freisetzung von löslichen Mediatoren nach Myokardischämie einen entscheidenden Anteil an der postischämischen Regulation der Vasomotion hat. Allerdings weniger bekannt ist die Bedeutung einer Mediator-vermittelten kardialen Autoregulation bei postischämischen Veränderungen der Myokardkontraktilität. In dieser Arbeit wird eine n
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16

Tajik, Bashir. "DOES INTRAVENOUS GLUTAMATE INFUSION INFLUENCE THE USE OF INOTROPIC DRUGS IN PATIENTS OPERATED FOR ACUTE CORONARY SYNDROME?" Thesis, Linköpings universitet, Hälsouniversitetets läkarutbildning, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-129973.

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Introduction: In a double-blind randomized clinical trial (GLUTAMICS-ClinicalTrials.gov Identifier: NCT00489827), intravenous glutamate was associated with a risk reduction exceeding 50% for developing severe circulatory failure after isolated coronary artery bypass graft (CABG) for acute coronary syndrome (ACS). Here our aim was to investigate if glutamate also influenced the need or use of inotropes. Methods: Post hoc analysis of 824 patients in the GLUTAMICS-trial operated with isolated CABG for ACS. ICU-records were retrospectively scrutinized including hourly registration of inotropic dru
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17

Bouwer, Carel Petrus. "A comparison on the release modifying behaviour of chitosan and kollidon SR / Carel Petrus Bouwer." Thesis, North-West University, 2007. http://hdl.handle.net/10394/1065.

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Controlled release formulations deliver an active ingredient over an extended period of time. It is an ideal dosage form for an active ingredient with a short elimination half-life. An active ingredient with a short elimination half-life would be released in small portions over an extended period of time and thus less frequent administration is necessary and this improve patient compliance. Other advantages of these formulations include: decreased side effects, constant drug levels in the blood, improvement in treatment efficiency and reduction in cost of administration. Controlled release be
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18

Wathen, Christopher George. "Studies of the cardiovascular effects of inotropic agents and vasodilators on the pulmonary and systemic circulation in man." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/27032.

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19

Liu, Zhan-Qiu. "QUANTIFICATION OF MYOCARDIAL MECHANICS IN LEFT VENTRICLES UNDER INOTROPIC STIMULATION AND IN HEALTHY RIGHT VENTRICLES USING 3D DENSE CMR." UKnowledge, 2019. https://uknowledge.uky.edu/me_etds/130.

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Statistical data from clinical studies indicate that the death rate caused by heart disease has decreased due to an increased use of evidence-based medical therapies. This includes the use of magnetic resonance imaging (MRI), which is one of the most common non-invasive approaches in evidence-based health care research. In the current work, I present 3D Lagrangian strains and torsion in the left ventricle of healthy and isoproterenol-stimulated rats, which were investigated using Displacement ENcoding with Stimulated Echoes (DENSE) cardiac magnetic resonance (CMR) imaging. With the implementat
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20

Ritterhoff, Julia [Verfasser], and Martin [Akademischer Betreuer] Müller. "S100A1 acts positive inotropic and prevents Ca2+ triggered after-contractions in a model of Engineered Heart Tissue / Julia Ritterhoff ; Betreuer: Martin Müller." Heidelberg : Universitätsbibliothek Heidelberg, 2013. http://d-nb.info/1177809273/34.

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21

Verwey, Werner Jaun. "Influence of modified release excipients on ketoprofen release from chitosan particles / W.J. Verwey." Thesis, North-West University, 2005. http://hdl.handle.net/10394/1034.

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Controlled release formulations offer many advantages over conventional dosage forms. These include reduced plasma fluctuations and improved patient comp1i:nce. Complex controlled release formulations such as those with enteric release properties, often require additional steps in the production phase. The costs and economic impact associated with these complex controlled release dosage formulations often outweigh the immediate benefits. Thus the development of an economic method to produce controlled release particles is of great importance especially in third world countries. In controlled r
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22

Sasipong, Nuttarak [Verfasser], and Markus [Akademischer Betreuer] Hecker. "Targeted overexpression of relaxin receptor 1 (RXFP1) with chronic administration of relaxin as a novel inotropic approach for heart failure treatment / Nuttarak Sasipong ; Betreuer: Markus Hecker." Heidelberg : Universitätsbibliothek Heidelberg, 2020. http://d-nb.info/1220836273/34.

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23

Havinga, Riana. "The effect of pharmaceutical excipients on the release of indomethacin from chitosan beads / Riana Havinga." Thesis, North-West University, 2006. http://hdl.handle.net/10394/4.

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Contents: Chitosan -- Controlled drug delivery -- Indomethacin -- Inotropic gelation -- Tripolyphosphate (TPP) -- Explotab® -- Ac-Di-Sol® -- Vitamin C<br>Thesis (M.Sc. (Pharmaceutics))--North-West University, Potchefstroom Campus, 2007.
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Mustroph, Julian [Verfasser], and Lars S. [Akademischer Betreuer] Maier. "SR Ca2+-leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure / Julian Mustroph ; Betreuer: Lars S. Maier." Regensburg : Universitätsbibliothek Regensburg, 2018. http://d-nb.info/1156008433/34.

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25

Dolce, Bernardo [Verfasser]. "Die Rolle der PDE4 für Inotropie und elektrische Stabilität im menschlichen Vorhof : Role of PDE4 for Inotropy and Electrical Stability in Human Atrium / Bernardo Dolce." Hamburg : Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky, 2019. http://d-nb.info/122108402X/34.

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26

Stangl, Verena. "Charakterisierung negativ inotroper Substanzen nach Myokardischämie." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=964532085.

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27

Trenque, Thierry. "Premières études chez l'homme d'un nouvel inotrope : l'INO 2628 CZ." Paris 12, 1991. http://www.theses.fr/1991PA120022.

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Les premieres etudes cliniques d'un nouvel inotrope positif, l'ino 2628 cz, sont decrites chez l'homme apres le rappel des etudes precliniques effectuees au prealable (pharmacologie, toxicologie, pharmacocinetique animale). Il est objective une augmentation significative du debit cardiaque chez le patient, mais egalement une propriete interessante du produit par rapport aux autres familles d'inotropes, a savoir son administration possible par voie orale, du fait d'une absorption rapide, d'une demi-vie d'elimination longue et d'une activite inotrope persistante jusqu'a la sixieme heure. Lors de
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Razafinjatovo, Jean-Jacques. "Inhibiteurs de phosphodiestérases et autres inotropes positifs apparentes." Strasbourg 1, 1988. http://www.theses.fr/1988STR15067.

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29

Murat, Isabelle. "Mecanismes d'action des effets inotropes negatifs des anesthesiques halogenes." Paris 11, 1990. http://www.theses.fr/1990PA112029.

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Les effets inotropes negatifs de l'halothane, enflurane et isoflurane, ont ete etudies sur le muscle papillaire de furet. Ces trois agents diminuent de facon dose-dependante et reversible la contracbilite isometrique et isotonique du muscle cardiaque. Ils diminuent egalement de facon dose-dependante et reversible la sensibilite a la charge du muscle papillaire de furet. Ces effets observes sur le muscle entier sont la consequence des efets elementaires de ces anesthesiques sur la membrane sarcolemmique et sur le reticulum sarcoplasmique et de leurs effets sur les proteines contractiles de la c
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30

Ballu, Olivier. "Exploration de la fonction inotrope chez le cobaye anesthésié." Paris 5, 1990. http://www.theses.fr/1990PA05P165.

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31

Weintraub, Joe͏̈lle. "Les hétérosides cardiotoniques : propriétés pharmacologiques et mécanisme de leur action inotrope positive." Paris 5, 1988. http://www.theses.fr/1988PA05P057.

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32

Linardi, Marcio. "Estudo da sensibilidade aos efeitos cronotropico e inotropico das catecolaminas em atrios isolados de ratos submetidosa treinamento fisico." [s.n.], 1992. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314613.

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Orientador : Regina Celia Spadari<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-07-17T08:42:17Z (GMT). No. of bitstreams: 1 Linardi_Marcio_M.pdf: 2161273 bytes, checksum: d6a2a16d3c6893996dfbc4bb0de81e4c (MD5) Previous issue date: 1992<br>Resumo: O ¿stress¿ se reflete em estímulo nervoso e humoral, através da ativação do sistema nervoso simpático e do eixo hipotálamo-adrenal, que resulta em aumento dos níveis plasmáticos de catecolamina e de glicocorticóides. O exercício físico, por constituir um trabalho biológico, e
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33

Kinkel, Hans-Tilmann [Verfasser]. "Erhöhte endogene Relaxin Expression im Myokard spontan-hypertensiver Ratten : Auswirkungen auf Inotropie und myokardiale Hypertrophie / Hans-Tilmann Kinkel." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2008. http://d-nb.info/1027496970/34.

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34

Bernadet, Philippe. "Etude de la cinétique de contraction segmentaire du ventricule gauche sous inotropes dans les myocardiopathies." Bordeaux 2, 1991. http://www.theses.fr/1991BOR23105.

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Gautier, Arnaud. "Synthese et etude de derives soufres en serie imidazol (1,2-a) pyridinique : mise en evidence d'activites inotropes." Clermont-Ferrand 1, 1995. http://www.theses.fr/1995CLF1PP06.

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Riado, Sonia Regina. "Inibição cronica da sintese de oxido nitrico em ratos : respostas cronotropicas e inotropicas em atrios isolados." [s.n.], 1999. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308953.

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Orientadores: Edson Antunes, Angelina Zanesco<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-07-25T01:01:21Z (GMT). No. of bitstreams: 1 Riado_SoniaRegina_M.pdf: 2336612 bytes, checksum: 055072902e1d16daa20f32c9ccb9136b (MD5) Previous issue date: 1999<br>Resumo: A administração crônica do inibidor da síntese de óxido nítrico N?-nitro-L arginina metil ester (L-NAME) em ratos induz à hipertensão arterial acompanhada por hipertrofia ventricular esquerda e lesões miocárdicas. O aumento do tônus simpático, a partici
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37

Weisselberg, Tilman Wilhelm. "Die Wirkung von Stickstoffmonoxid auf Isoprenalin-induzierte positiv inotrope Effekte beim hypertrophierten Herzen der Ratte." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=963216902.

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38

Platonoff, Nadine. "Nouvelles méthodes de microscopie quantitative appliquées à l'étude de la relation calcium libre intracellulaire-inotropie sur cellules cardiaques de rats nouveaux-nés." Besançon, 1989. http://www.theses.fr/1989BESA2038.

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Relation ca inotropie sur cellules de rat neo-natal en culture: deux nouveaux dispositifs optiques appliques a la microscopie ont ete developpes pour mesurer les parametres de contraction et la concentration en ions calcium libres sur des cellules en culture: un contractometre base sur la diffusion de lumiere dynamique et un microspectrofluorimetre adapte aux sondes intra-cellulaires. L'etalonnage de ces instruments a ete particulierement etudie et les causes d'erreur minimisees. A l'aide de ces dispositifs, la relation calcium interne-contraction a ete examinee en presence de substances connu
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RUSCONI, FRANCESCA. "THE IMPORTANT ROLE OF AKT IN THE MODULATION OF HEART INOTROPISM THROUGH L-TYPE CALCIUM CHANNELS FUNCTION." Doctoral thesis, Università degli Studi di Milano, 2010. http://hdl.handle.net/2434/150100.

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The insulin IGF1/Akt signaling pathway has recently been shown to be critical for the regulation of heart function and physiology. Indeed, compelling evidence shows activation of this pathway as one of the most important determinants for the enhancement of cardiac function and physiological growth in athletes, whereas its impairment is considered critical for the development of heart failure (HF). In this doctoral thesis, our aim was to determine the functional role of known and novel key-factors of this pathway to study whether their modulation might be envisaged as therapeutic tool for curin
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Canovas, Michèle. "Influence du pool calcique intracellulaire sur la réponse inotrope des préparations myocardiques isolées soumises à l'adénosine." Montpellier 1, 1994. http://www.theses.fr/1994MON1T004.

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Biais, Matthieu. "Stratégie d’optimisation hémodynamique des patients à risque : impacts de l’acidose respiratoire et métabolique, du clampage de l’aorte abdominale sous-rénale et du positionnement peropératoire." Thesis, Bordeaux 2, 2013. http://www.theses.fr/2013BOR22095/document.

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L’optimisation hémodynamique péri-opératoire est une stratégie qui vise à maximaliser le transport artériel en oxygène et/ou le volume d’éjection systolique lors de chirurgie à risque. Ce concept a beaucoup évolué lors de ces trente dernières années, vers une approche plus simple, plus réalisable en pratique clinique et moins invasive. Les principales thérapeutiques utilisées dans les différents protocoles d’optimisation hémodynamique sont le remplissage vasculaire, l’administration d’agents inotropes et de vasopresseurs. Cependant, les conséquences physiopathologiques de l’agression chirurgic
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Quiniou, Gilles. "Les nouveaux inotropes positifs dans le traitement de l'insuffisance cardiaque, à propos d'une étude ouverte au centre hospitalier de la côte basque sur l'Enoxinome oral." Bordeaux 2, 1989. http://www.theses.fr/1989BOR25216.

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43

Torres, Carlos Alexandre Andrade. "On the Role of Heart Rate Variability and Pyruvate on Cardiac Contractility." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1398688195.

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44

Sharaff, Fathima Farveen Casim Sahib Mohammed. "The role of catecholamine stress hormones and inotropes in the promotion of bacterial growth, virulence and biofilm formation." Thesis, University of Leicester, 2012. http://hdl.handle.net/2381/11044.

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Bacteria in most environments exist and grow in association with surfaces, leading to formation of biofilms. In the medical context, biofilms are particularly significant for human health because of their high resistance to antimicrobial and immune system attack. In the health care setting biofilms associated with indwelling devices such as intravenous catheters and endotracheal tubes is a major clinical problem. It has been shown in previous reports that catecholamine stress hormones such as epinephrine, norepinephrine and structurally similar inotrope drugs used to treat heart and kidney pro
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Marciniak, Gilbert. "Nouveaux heterocycles doues d'activites antiangineuses, inotropes positives ou antagonistes des canaux calciques : synthese, modelisation et relations structure-activite." Université Louis Pasteur (Strasbourg) (1971-2008), 1987. http://www.theses.fr/1987STR13142.

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Recherche par modelisation moleculaire sur ordinateur d'une structure commune a cinq inotrpes positifs connus ; synthese et proprietes pharmacologiques de nouveaux inotropes positifs (pyridyl-quinoles) ; preparation et pharmacologie de composes apparentes a la perhexiline ; synthese et activite biologique de dihydropyridines
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Marciniak, Gilbert. "Nouveaux hétérocycles doués d'activités antiangineuses, inotropes positives ou antagonistes des canaux calciques synthèse, modélisation et relations structure-activité /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37607708r.

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47

Mansier, Pascale. "Contribution a l'etude de l'effet inotrope des digitaliques dans le coeur de mammifere : role du calcium membranaire." Paris 7, 1987. http://www.theses.fr/1987PA077286.

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Bien que les derives digitaliques soient utilises frequemment en cas de defaillance cardiaque, leur mecanisme d'action est mal connu. Une etude biochimique des recepteurs de ces drogues a ete entreprise et a permis de relier l'atpase-(na, k) et l'effet inotrope des digitaliques. La mise au point d'une preparation de sarcolemme a partir de coeurs de rats adultes ou de lapins adultes a ete realisee
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48

Musarneh, Muntaser Darwish Mustafa. "The Effects of Carbon Monoxide Releasing Molecules (CO-RMS) in Myocardial Inotropy and Protection Against Ischaemia-Reperfusion Injury." Thesis, University College London (University of London), 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487768.

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Myocardial ischaemia reperfusion injury is common in clinical prac.tice. Myocardial infarction is a good example, in which prolonged coronary artery occlusion by a thrombus may be followed by reperfusion either spontaneously or by medical intervention with thrombolytic drugs or acute angioplasty. The heart may also undergo ischaemia-reperfusion during operations that require temporary interruption of myocardial blood supply s~ch as, coronary artery bypass grafting and heart transplantation. Carbon monoxide, one of the products of haem degradation by the enzyme haem oxygenase, has been shown to
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49

Tompers, Jo [Verfasser]. "Wirkung von milder Hypothermie auf den negativ inotropen Effekt von Halothan, Isofluran und Sevofluran auf ventrikuläres Kaninchen Myokard / Jo Tompers." Aachen : Hochschulbibliothek der Rheinisch-Westfälischen Technischen Hochschule Aachen, 2011. http://d-nb.info/1014457769/34.

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50

Heinicke, Thomas. "Inotrope Wirkungen bei [beta]-adrenerger [Beta-adrenerger] Stimulation und antiadrenerger Effekt von ACh in endothelial NO-Synthase defizienten Mäuseherzen." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=970942915.

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