Log in

Relevant bibliographies by topics / INRS / Journal articles

To see the other types of publications on this topic, follow the link: INRS.

Journal articles on the topic 'INRS'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'INRS.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Rowe, Shaneel, and Kaitlin M. Best. "Individualized Numeric Rating Scale to Assess Pain in Critically Ill Children With Neurodevelopmental Disabilities." American Journal of Critical Care 33, no. 4 (2024): 280–88. http://dx.doi.org/10.4037/ajcc2024343.

Full text

Abstract:

Background Pain is a significant burden for children with neurodevelopmental disabilities but is difficult for clinicians to identify. No pain assessment tools for children with neurodevelopmental disabilities have been validated for use in pediatric intensive care units. The Individualized Numeric Rating Scale (INRS) is an adapted 0-to-10 rating that includes parents’ input on their child’s pain indicators. Objectives To evaluate the reliability, validity, and feasibility and acceptability of use of the INRS for assessing pain in critically ill children with neurodevelopmental disabilities. M

APA, Harvard, Vancouver, ISO, and other styles

2

LI, JUN, XIANZHONG DAI, ZHENGDA MENG, and LIBO XU. "IMPROVED NET REWRITING SYSTEMS–EXTENDED PETRI NETS SUPPORTING DYNAMIC CHANGES." Journal of Circuits, Systems and Computers 17, no. 06 (2008): 1027–52. http://dx.doi.org/10.1142/s0218126608004794.

Full text

Abstract:

The existing extensions of Petri nets supporting dynamic changes cannot ensure preservation of desired properties of the modeled systems. This paper tries to address this problem. By extending the structure of the net rewriting system (NRS) and modifying the specification of its rewriting rule, we present improved net rewriting system (INRS). INRS enjoys four important properties, i.e., locality, transitivity, reflexivity, and reversibility. A practical system subject to dynamic changes can be modeled by an INRS, and its desired properties can be preserved with the state evolvement of the INRS

APA, Harvard, Vancouver, ISO, and other styles

3

Kitchen, S., I. D. Walker, T. A. L. Woods, and F. E. Preston. "Thromboplastin Related Differences in the Determination of International Normalised Ratio: A Cause for Concern?" Thrombosis and Haemostasis 72, no. 03 (1994): 426–29. http://dx.doi.org/10.1055/s-0038-1648883.

Full text

Abstract:

SummaryWhen the International Normalised Ratio (INR) is used for control of oral anticoagulant therapy the same result should be obtained irrespective of the laboratory reagent used. However, in the UK National External Quality Assessment Scheme (NEQAS) for Blood Coagulation INRs determined using different reagents have been significantly different.For 18 NEQAS samples Manchester Reagent (MR) was associated with significantly lower INRs than those obtained using Diagen Activated (DA, p = 0.0004) or Instrumentation Laboratory PT-Fib HS (IL, p = 0.0001). Mean INRs for this group were 3.15, 3.61,

APA, Harvard, Vancouver, ISO, and other styles

4

Gosselin, Robert, Richard White, Rose Hutchinson, et al. "A Comparison of Point-of-Care Instruments Designed for Monitoring Oral Anticoagulation with Standard Laboratory Methods." Thrombosis and Haemostasis 83, no. 05 (2000): 698–703. http://dx.doi.org/10.1055/s-0037-1613895.

Full text

Abstract:

SummaryOur study compared point-of-care (POC) device monitoring with traditional clinical laboratory methods device of patients on oral anticoagulant therapy. The POC devices used in the study were Coumatrak, CoaguChek, CoaguChek Plus, Thrombolytic Assessment System (TAS) PT-One, TAS PTNC, TAS PT, Hemachron Jr. Signature, Protime Microcoagulation System, and Medtronics ACT II. The clinical laboratory method used thromboplastins with different ISI values: Innovin and Thromboplastin C Plus (TPC). All POC INRs showed strong correlation with both laboratory methods, with correlation coefficients o

APA, Harvard, Vancouver, ISO, and other styles

5

Benzon, Honorio T., Michael J. Avram, Hubert A. Benzon, Misty Kirby-Nolan, and Antoun Nader. "Factor VII Levels and International Normalized Ratios in the Early Phase of Warfarin Therapy." Anesthesiology 112, no. 2 (2010): 298–304. http://dx.doi.org/10.1097/aln.0b013e3181ca6cfc.

Full text

Abstract:

Background Factor VII is the most affected clotting factor during the early phase of warfarin therapy. An international normalized ratio (INR) of more than 1.4 is considered unsafe for epidural catheter placement or removal, according to the American Society of Regional Anesthesia and Pain Medicine. The authors tested the hypothesis that factor VII activities would be consistent with safe removal of the epidural catheter on postoperative day (POD) 1 regardless of INR value. Methods Data from 121 patients who took warfarin after undergoing total joint surgery and had INRs and factor VII levels

APA, Harvard, Vancouver, ISO, and other styles

6

Foster, Andrew W., Carl J. Patterson, Rafael Pernil, Corinna R. Hess, and Nigel J. Robinson. "Cytosolic Ni(II) Sensor in Cyanobacterium." Journal of Biological Chemistry 287, no. 15 (2012): 12142–51. http://dx.doi.org/10.1074/jbc.m111.338301.

Full text

Abstract:

Efflux of surplus Ni(II) across the outer and inner membranes of Synechocystis PCC 6803 is mediated by the Nrs system under the control of a sensor of periplasmic Ni(II), NrsS. Here, we show that the product of ORF sll0176, which encodes a CsoR/RcnR-like protein now designated InrS (for internal nickel-responsive sensor), represses nrsD (NrsD is deduced to efflux Ni(II) across the inner membrane) from a cryptic promoter between the final two ORFs in the nrs operon. Transcripts initiated from the newly identified nrsD promoter accumulate in response to nickel or cobalt but not copper, and recom

APA, Harvard, Vancouver, ISO, and other styles

7

Earl, Marc A., and Vincent F. Mauro. "The Clinical Impact of Administering Warfarin to Post-Myocardial Infarction Patients." Journal of Pharmacy Practice 17, no. 4 (2004): 266–69. http://dx.doi.org/10.1177/0897190004268652.

Full text

Abstract:

This article reviews recent trials that have compared aspirin to anticoagulation in post-myocardial infarction (MI) patients. Warfarin dosed to international normalized ratios (INRs) between 2.8 and 4.2 was superior to placebo in reducing morbidity and mortality; however, post-MI patients are generally receiving aspirin. When aspirin therapy was compared to warfarin plus aspirin, no clinical benefit occurred when warfarin was dosed to achieve INRs less than 2.0. In contrast, warfarin reduced morbidity and mortality compared to aspirin when it was dosed as monotherapy to achieve INRs between 3.

APA, Harvard, Vancouver, ISO, and other styles

8

Fu, Yuping, Yan Liu, Zhiying Liu, et al. "The Impact of microRNA Regulation on Immune Recovery in HIV-1-Infected Patients Treated during Acute Infection: A Pilot Study." BioMed Research International 2020 (December 4, 2020): 1–12. http://dx.doi.org/10.1155/2020/5782927.

Full text

Abstract:

microRNAs (miRNAs) are small noncoding RNAs involved in a large range of cellular activities and can be used as biomarkers and indicators for diagnosis. We investigated the alterations in miRNA profiles in immune reconstituted vs. nonimmune reconstituted HIV-1-infected individuals to assess the association between miRNAs and the occurrence of immunological nonresponses, with the aim of searching for miRNA-based biomarkers for these HIV-1-infected individuals. Thirteen immunological responders (IRs) and 12 immunological nonresponders (INRs) were recruited, and RNA was collected from the plasma

APA, Harvard, Vancouver, ISO, and other styles

9

Hutten, Barbara, Nathalie Péquériaux, Fred Haas, Marcel Levi, Augueste Sturk, and Johanna van Geest-Daalderop. "The influence on INRs and coagulation factors of the time span between blood sample collection and intake of phenprocoumon or acenocoumarol: Consequences for the assessment of the dose." Thrombosis and Haemostasis 98, no. 10 (2007): 738–46. http://dx.doi.org/10.1160/th06-11-0645.

Full text

Abstract:

SummaryManaging treatment with vitamin K antagonists, the prothrombin time (PT),expressed as international normalized ratio (INR), may not represent the INR during the entire 24 hour (h) period, and this variation may be different between long-acting phenprocoumon and short-acting acenocoumarol. For both drugs we investigated the variation in 24 h of the PT/INR, the consequences for the assessment of the doses and which vitamin K-dependent factor causes the daily variation. Patients on self-management took their medication at 6 p.m. and determined their INRs for eight weeks, once a week and th

APA, Harvard, Vancouver, ISO, and other styles

10

Kitchen, S., I. Jennings, T. A. L. Woods, I. D. Walker, and F. E. Preston. "Two Recombinant Tissue Factor Reagents Compared to Conventional Thromboplastins for Determination of International Normalised Ratio: A Thirty-three-laboratory Collaborative Study." Thrombosis and Haemostasis 76, no. 03 (1996): 372–76. http://dx.doi.org/10.1055/s-0038-1650586.

Full text

Abstract:

SummaryRecent advances in recombinant technology have led to the development of prothrombin time (PT) reagents containing recombinant tissue factor which has been lipidated to allow expression of procoagulant activity. In this study we have compared International Normalised Ratios (INRs) determined using two such reagents and conventional thromboplastins in widespread use in the UK.Lyophilised plasma samples from eight different warfarinised patients were distributed to 33 laboratories in the UK. Each participant determined prothrombin times on 20 local fresh normal plasmas (used to derive mea

APA, Harvard, Vancouver, ISO, and other styles

11

Havrda, Dawn E., Toni L. Hawk, and Carrie M. Marvin. "Accuracy and Precision of the CoaguChek S versus Laboratory INRs in a Clinic." Annals of Pharmacotherapy 36, no. 5 (2002): 769–75. http://dx.doi.org/10.1345/aph.1a310.

Full text

Abstract:

BACKGROUND: The CoaguChek S is the next-generation coagulation monitor for measuring the international normalized ratio (INR) that replaces the CoaguChek device. Studies are lacking comparing the CoaguChek S with local laboratory INR assessment to ensure its accuracy and precision for monitoring patients on anticoagulation. OBJECTIVE: To evaluate accuracy, precision, and technical ease-of-use of the CoaguChek S compared with laboratory measurements. METHODS: Accuracy was evaluated in 101 patients by parallel assessment of INRs (CoaguChek S and laboratory); precision was evaluated in 31 patient

APA, Harvard, Vancouver, ISO, and other styles

12

Rousseau, Rodney, Yoojin Choi, Elizabeth Lau, et al. "Immunologic non-response during HIV infection is characterized by systemic immune activation." Journal of Immunology 198, no. 1_Supplement (2017): 125.3. http://dx.doi.org/10.4049/jimmunol.198.supp.125.3.

Full text

Abstract:

Abstract Introduction Despite effective treatment HIV infection is characterized by non-AIDS health burdens, linked to immune activation, gut damage and microbial translocation. Some HIV+ individuals achieve viral suppression but do not recover blood CD4 T cells; these immunologic non-responders (INRs) are at elevated disease risk. We hypothesized that INRs have higher immune activation and markers related to gut damage, as compared to HIV+ treatment responders (TRs). Methods Thirty-six men who have sex with men (MSM) were recruited through the Maple Leaf Medical Clinic in Toronto. INRs (n=15)

APA, Harvard, Vancouver, ISO, and other styles

13

DiCicco, R. A., M. J. Hursting, T. Montague, D. K. Jorkasky, and S. B. Sheth. "Interpreting the International Normalized Ratio (INR) in Individuals Receiving Argatroban and Warfarin." Thrombosis and Haemostasis 85, no. 03 (2001): 435–40. http://dx.doi.org/10.1055/s-0037-1615601.

Full text

Abstract:

SummaryThe effects of argatroban, a direct thrombin inhibitor, on the International Normalized Ratio (INR), activated partial thromboplastin time (aPTT) and functional factor X during warfarin co-administration were established to provide means to interpret INRs during argatroban/warfarin co-therapy. Twenty-four subjects receiving warfarin (7.5 mg, day 1; 3-6 mg/day, days 2-10) and argatroban (1-4 μg/kg/min over 5 h, days 1-11) were assessed daily for these coagulation parameters prior to argatroban infusion (warfarin “monotherapy”) and at its conclusion (“co-therapy”). Argatroban increased aP

APA, Harvard, Vancouver, ISO, and other styles

14

Jennings, I., T. A. L. Woods, F. E. Preston, and S. Kitchen. "Local Calibration of International Normalised Ratio Improves between Laboratory Agreement: Results from the UK National External Quality Assessment Scheme." Thrombosis and Haemostasis 81, no. 01 (1999): 60–65. http://dx.doi.org/10.1055/s-0037-1614419.

Full text

Abstract:

SummaryIn the present study we have performed local calibration of International Normalised Ratio (INR) measurement systems in a large series of laboratories. We assigned INRs to five lyophilised plasma calibrants, one prepared from normal plasma and four using plasma from war-farinised patients, using different International Reference Preparations for Thromboplastin. These five calibrants, and two lyophilised test plasmas were analysed by 349 centres using 60 different thromboplastin instrument combinations.Plasma calibrants were assigned INRs using the WHO reference thromboplastin RBT-90 or

APA, Harvard, Vancouver, ISO, and other styles

15

Prins, Martin, W. Ken Redekop, Jan Tijssen, Siem Heisterkamp, Harry Büller, and Barbara Hutten. "Comparison of Three Methods to Assess Therapeutic Quality Control of Treatment with Vitamin K Antagonists." Thrombosis and Haemostasis 82, no. 10 (1999): 1260–63. http://dx.doi.org/10.1055/s-0037-1614372.

Full text

Abstract:

SummaryDuring treatment with vitamin K antagonists, International Normalized Ratios (INR) are determined periodically to maintain a therapeutic level of anticoagulation. We evaluated two existing methods for therapeutic quality control (linear interpolation and equidivision), with regard to their validity and reproducibility. In addition, we proposed and evaluated a (hybrid) method that takes into account potential effects of dosage modifications when INRs are far out of the target range. Validity was assessed by deleting intermediary INR results and estimating this INR based on the two surrou

APA, Harvard, Vancouver, ISO, and other styles

16

Smýkal, Vlastimil, Martin Pivarči, Jan Provazník, et al. "Complex Evolution of Insect Insulin Receptors and Homologous Decoy Receptors, and Functional Significance of Their Multiplicity." Molecular Biology and Evolution 37, no. 6 (2020): 1775–89. http://dx.doi.org/10.1093/molbev/msaa048.

Full text

Abstract:

Abstract Evidence accumulates that the functional plasticity of insulin and insulin-like growth factor signaling in insects could spring, among others, from the multiplicity of insulin receptors (InRs). Their multiple variants may be implemented in the control of insect polyphenism, such as wing or caste polyphenism. Here, we present a comprehensive phylogenetic analysis of insect InR sequences in 118 species from 23 orders and investigate the role of three InRs identified in the linden bug, Pyrrhocoris apterus, in wing polymorphism control. We identified two gene clusters (Clusters I and II)

APA, Harvard, Vancouver, ISO, and other styles

17

&NA;. "Taking another look at INRs." Inpharma Weekly &NA;, no. 958 (1994): 19. http://dx.doi.org/10.2165/00128413-199409580-00043.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

King, Alexandra. "Target INRs for cardiac indications." Nature Reviews Cardiology 6, no. 10 (2009): 613. http://dx.doi.org/10.1038/nrcardio.2009.142.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Patriquin, Christopher Jordan, Ian H. Chin-Yee, Michael J. Kovacs, Alejandro Lazo-Langner, Michael Keeney, and Cyrus C. Hsia. "Study of Octaplex Dosing Accuracy: An In Vitro Analysis." Blood 118, no. 21 (2011): 4335. http://dx.doi.org/10.1182/blood.v118.21.4335.4335.

Full text

Abstract:

Abstract Abstract 4335 Background: Supratherapeutic INRs are common with warfarin therapy, and increase serious bleeding risk. Octaplex is a prothrombin complex concentrates (PCC) that is recommended for urgent warfarin reversal. However, disagreement exists regarding proper dosing strategies (fixed versus weight-based). Objectives: We sought to measure the in vitro effect of Octaplex on INR and factor levels, and to characterize this relationship. Methods: Plasma samples from eligible patients on warfarin with stable INRs for ≥4 weeks were collected. Plasma volumes were calculated to approxim

APA, Harvard, Vancouver, ISO, and other styles

20

Khan, Osama, Mario Capitano, Susan Fan, and John Woulfe. "Observations of the Morphological Evolution of Neuronal Intranuclear Rods in the Human Substantia Nigra Across the Age Spectrum." American Journal of Clinical Pathology 152, Supplement_1 (2019): S76. http://dx.doi.org/10.1093/ajcp/aqz114.001.

Full text

Abstract:

Abstract Objectives Parkinson’s disease (PD) is a neurodegenerative disease characterized by a depletion of dopaminergic neurons in the substansia nigra (SN). Loss of SN neurons occurs at a rate of up to 10% per decade in nonpathological aging. Other age-related changes in nigral neurons include accumulation of intranuclear inclusions called Marinesco bodies (MBs). MBs have been shown to associate with a distinct type of neuronal intranuclear body called the intranuclear rod (INR). At what point in the aging process INRs develop, and when they give rise to MBs, are questions that remain unansw

APA, Harvard, Vancouver, ISO, and other styles

21

van den Besselaar, Anton M. H. P., and Wim P. M. Houdijk. "Use of Lyophilized Calibrant Plasmas for Simplified International Normalized Ratio Determination with a Human Tissue Factor Thromboplastin Reagent Derived from Cultured Human Cells." Clinical Chemistry 49, no. 12 (2003): 2006–11. http://dx.doi.org/10.1373/clinchem.2003.023531.

Full text

Abstract:

Abstract Background: For monitoring of treatment with oral anticoagulants, the clotting time obtained in the prothrombin time (PT) test is transformed to the International Normalized Ratio (INR) with use of a system-specific International Sensitivity Index (ISI). The calibrant plasma procedure (CPP) is an alternative approach to INR calculation based on the use of a set of lyophilized plasmas with assigned INRs. Methods: With the CPP, a linear relationship is established between log(PT) and log(INR), using orthogonal regression. CPP was validated for Simplastin HTF, a new human tissue factor r

APA, Harvard, Vancouver, ISO, and other styles

22

Liu, Jiamin, Chengchao Ding, Yu Shi, et al. "Advances in Mechanism of HIV-1 Immune Reconstitution Failure: Understanding Lymphocyte Subpopulations and Interventions for Immunological Nonresponders." Journal of Immunology 212, no. 11 (2024): 1609–20. http://dx.doi.org/10.4049/jimmunol.2300777.

Full text

Abstract:

Abstract In individuals diagnosed with AIDS, the primary method of sustained suppression of HIV-1 replication is antiretroviral therapy, which systematically increases CD4+ T cell levels and restores immune function. However, there is still a subset of 10–40% of people living with HIV who not only fail to reach normal CD4+ T cell counts but also experience severe immune dysfunction. These individuals are referred to as immunological nonresponders (INRs). INRs have a higher susceptibility to opportunistic infections and non–AIDS-related illnesses, resulting in increased morbidity and mortality

APA, Harvard, Vancouver, ISO, and other styles

23

Saidakova, E. V., L. B. Korolevskaya, N. G. Shmagel, et al. "IN HIV-INFECTED IMMUNOLOGICAL NON-RESPONDERS, HEPATITIS C VIRUS ERADICATION CONTRIBUTES TO INCOMPLETE NORMALIZATION OF SYSTEMIC INFLAMMATION INDEXES, BUT DOES NOT LEAD TO RAPID CD4<sup>+</sup> T-CELL COUNT RECOVERY." Доклады Российской академии наук. Науки о жизни 512, no. 1 (2023): 454–59. http://dx.doi.org/10.31857/s2686738923600243.

Full text

Abstract:

In HIV-positive individuals taking antiretroviral therapy, coinfection with hepatitis C virus (HCV) increases the systemic inflammation, which interferes with the CD4+ T-cells regeneration. This study evaluated the effect of HCV eradication on systemic inflammation and CD4+ T-cell regeneration in patients who gave poor response to antiretroviral therapy, the so-called “immunological non-responders” (INRs). HIV-infected patients who received a course of direct-acting antiviral drugs for treating hepatitis C were examined. The control groups included HIV/HCV-coinfected individuals and relatively

APA, Harvard, Vancouver, ISO, and other styles

24

Li, Chun, Ute I. Schwarz, Marylyn D. Ritchie, Dan M. Roden, C. Michael Stein, and Daniel Kurnik. "Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy." Blood 113, no. 17 (2009): 3925–30. http://dx.doi.org/10.1182/blood-2008-09-176859.

Full text

Abstract:

Abstract Genetic variants in CYP2C9 and VKORC1 strongly affect steady-state warfarin dose. However, these variants also affect early international normalized ratio (INR) values during warfarin initiation. We examined whether CYP2C9/VKORC1 genotypes provide information about warfarin sensitivity additional to that provided by early INR responses. In 214 patients starting warfarin with INR-guided dose adjustments, we determined whether CYP2C9 and VKORC1 genotypes were associated with early measures of warfarin sensitivity (time to INR ≥ lower limit of therapeutic range; time to INR > 4; and f

APA, Harvard, Vancouver, ISO, and other styles

25

Harenberg, Job, Christel Weiss, Marie-Theres Felten, and Lutz Frölich. "Stability of the INR in Relation to Personality Traits in Patients On Stable Oral Anticoagulant Therapy." Blood 114, no. 22 (2009): 4178. http://dx.doi.org/10.1182/blood.v114.22.4178.4178.

Full text

Abstract:

Abstract Abstract 4178 Maintenance of a stable anticoagulation as determined by the international standardized ratio (INR) remains difficult despite increasing knowledge on genetic variations of metabolism and improved therapeutic approaches. We hypothesised that personality traits of patients may influence the stability of the INR, obtained during stable therapy with vitamin-K antagonist (VKA). We assumed that the standard deviation (SD) of the INR over a time period of 6 months represents the stability of the anticoagulant treatment. Patients (n=28) treated with VKA for more than one year in

APA, Harvard, Vancouver, ISO, and other styles

26

Gaardbo, Julie C., Hans J. Hartling, Jan Gerstoft, and Susanne D. Nielsen. "Incomplete Immune Recovery in HIV Infection: Mechanisms, Relevance for Clinical Care, and Possible Solutions." Clinical and Developmental Immunology 2012 (2012): 1–17. http://dx.doi.org/10.1155/2012/670957.

Full text

Abstract:

Treatment of HIV-infected patients with highly active antiretroviral therapy (HAART) usually results in diminished viral replication, increasing CD4+ cell counts, a reversal of most immunological disturbances, and a reduction in risk of morbidity and mortality. However, approximately 20% of all HIV-infected patients do not achieve optimal immune reconstitution despite suppression of viral replication. These patients are referred to as immunological nonresponders (INRs). INRs present with severely altered immunological functions, including malfunction and diminished production of cells within l

APA, Harvard, Vancouver, ISO, and other styles

27

Wodwaski, Nadine. "Widely Fluctuating International Normalized Ratios (INRs)." Home Healthcare Now 36, no. 5 (2018): 335. http://dx.doi.org/10.1097/nhh.0000000000000733.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Murray, E. "INRs and point of care testing." BMJ 327, no. 7405 (2003): 5–6. http://dx.doi.org/10.1136/bmj.327.7405.5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Treharne Jones, Robert. "Testing for INRs: A computer approach." Practice Nursing 9, no. 6 (1998): 34–37. http://dx.doi.org/10.12968/pnur.1998.9.6.34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Han, Dongshen, and Chaoning Zhang. "Residual-Based Implicit Neural Representation for Synthetic Aperture Radar Images." Remote Sensing 16, no. 23 (2024): 4471. http://dx.doi.org/10.3390/rs16234471.

Full text

Abstract:

Implicit neural representations (INRs) are a new way to represent all kinds of signals ranging from 1D audio to 3D shape signals, among which 2D images are the most widely explored due to their ubiquitous presence. Image INRs utilize a neural network to learn a continuous function that takes pixel coordinates as input and outputs the corresponding pixel values. The continuous representation of synthetic aperture radar (SAR) images using INRs has not yet been explored. Existing INR frameworks developed on natural images show reasonable performance, but this performance suffers when capturing fi

APA, Harvard, Vancouver, ISO, and other styles

31

Maillardet, Louise, Yshai Yavin, and Alexander T. Cohen. "Will a once-weekly anticoagulant for the treatment and secondary prevention of thromboembolism improve adherence?" Thrombosis and Haemostasis 101, no. 03 (2009): 422–27. http://dx.doi.org/10.1160/th08-02-0094.

Full text

Abstract:

SummaryOral anticoagulation, most commonly with warfarin once daily, has long been the main form of long-term treatment and secondary prevention of thromboembolism. The efficacy of warfarin has been established in clinical trials, but problems with unstable anticoagulation with international normalized ratios (INRs) outside the recommended range due to incorrect dosing, drug and food interactions, and with adherence and persistence have been reported in practice. Poor adherence and persistence are serious problems because they result in out-of-range INRs. Many new thromboembolic events, such a

APA, Harvard, Vancouver, ISO, and other styles

32

van den Besselaar, Antonius M. H. P., and Christa M. Cobbaert. "Assignment of international normalized ratio to frozen and freeze-dried pooled plasmas." Clinical Chemistry and Laboratory Medicine (CCLM) 58, no. 12 (2020): 2089–97. http://dx.doi.org/10.1515/cclm-2019-1321.

Full text

Abstract:

AbstractObjectivesFrozen and freeze-dried plasmas may be used for local prothrombin time system calibration, for direct international normalized ratio (INR) determination, and for quality assessment. The purpose of the present study was to evaluate the usefulness of INRs assigned with various types of thromboplastins to frozen and freeze-dried pooled plasmas obtained from patients treated with vitamin K antagonists.MethodsINRs were calculated according to the international sensitivity index (ISI) model using various thromboplastins and instruments, i.e. International Standards for thromboplast

APA, Harvard, Vancouver, ISO, and other styles

33

Han, Dongshen, and Chaoning Zhang. "Self-Activated Implicit Neural Representation for Synthetic Aperture Radar Images." Remote Sensing 16, no. 23 (2024): 4473. http://dx.doi.org/10.3390/rs16234473.

Full text

Abstract:

Image Implicit Neural Representations (INRs) adopt a neural network to learn a continuous function for mapping the pixel coordinates to their corresponding values. This task has gained significant attention for representing images in a continuous manner. Despite substantial progress regarding natural images, there is little investigation of INRs for Synthetic Aperture Radar (SAR) images. This work takes a pioneering effort to study INRs for SAR images and finds that fine details are hard to represent. It has been shown in prior works that fine details can be easier to learn when the model weig

APA, Harvard, Vancouver, ISO, and other styles

34

Goldberg, Roy J., Louis A. Kaplan, Toni Ann Mooney, and Liezel T. Vince Cruz. "Keeping INRs Therapeutic: The Kings Harbor Protocol." Journal of the American Medical Directors Association 9, no. 3 (2008): B16. http://dx.doi.org/10.1016/j.jamda.2007.12.090.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Javahery, R., A. Khachi, K. Lo, B. Zenzie-Gregory, and S. T. Smale. "DNA sequence requirements for transcriptional initiator activity in mammalian cells." Molecular and Cellular Biology 14, no. 1 (1994): 116–27. http://dx.doi.org/10.1128/mcb.14.1.116-127.1994.

Full text

Abstract:

A transcriptional initiator (Inr) for mammalian RNA polymerase II can be defined as a DNA sequence element that overlaps a transcription start site and is sufficient for (i) determining the start site location in a promoter that lacks a TATA box and (ii) enhancing the strength of a promoter that contains a TATA box. We have prepared synthetic promoters containing random nucleotides downstream of Sp1 binding sites to determine the range of DNA sequences that convey Inr activity. Numerous sequences behaved as functional Inrs in an in vitro transcription assay, but the Inr activities varied drama

APA, Harvard, Vancouver, ISO, and other styles

36

Javahery, R., A. Khachi, K. Lo, B. Zenzie-Gregory, and S. T. Smale. "DNA sequence requirements for transcriptional initiator activity in mammalian cells." Molecular and Cellular Biology 14, no. 1 (1994): 116–27. http://dx.doi.org/10.1128/mcb.14.1.116.

Full text

Abstract:

A transcriptional initiator (Inr) for mammalian RNA polymerase II can be defined as a DNA sequence element that overlaps a transcription start site and is sufficient for (i) determining the start site location in a promoter that lacks a TATA box and (ii) enhancing the strength of a promoter that contains a TATA box. We have prepared synthetic promoters containing random nucleotides downstream of Sp1 binding sites to determine the range of DNA sequences that convey Inr activity. Numerous sequences behaved as functional Inrs in an in vitro transcription assay, but the Inr activities varied drama

APA, Harvard, Vancouver, ISO, and other styles

37

Gupta, Vasudha, Stephen J. Kogut, and Sarah Thompson. "Evaluation of Differences in Percentage of International Normalized Ratios in Range Between Pharmacist-Led and Physician-Led Anticoagulation Management Services." Journal of Pharmacy Practice 28, no. 3 (2013): 249–55. http://dx.doi.org/10.1177/0897190013516368.

Full text

Abstract:

Background: The safety and efficacy of warfarin depend on maintaining the international normalized ratio (INR) in an established range. Objective: The purpose was to determine whether a coordinated pharmacist-led approach improved percentage of INRs in therapeutic range in comparison to a physician-led anticoagulation management service (AMS). Methods: A retrospective chart review was conducted for patients at a multisite primary care organization. INR data for patients receiving warfarin management by a physician were collected from December 1, 2009 to May 31, 2010. These were compared to INR

APA, Harvard, Vancouver, ISO, and other styles

38

Crossley, Robert, Thomas Liebig, Markus Holtmannspoetter, et al. "Validation studies of virtual reality simulation performance metrics for mechanical thrombectomy in ischemic stroke." Journal of NeuroInterventional Surgery 11, no. 8 (2019): 775–80. http://dx.doi.org/10.1136/neurintsurg-2018-014510.

Full text

Abstract:

IntroductionMechanical thrombectomy (MT) has transformed the treatment of ischemic stroke. However, patient access to MT may be limited due to a shortage of doctors specifically trained to perform MT. The studies reported here were done to (1) develop, operationally define, and seek consensus from procedure experts on the metrics which best characterize a reference procedure for the performance of an MT for ischemic stroke and (2) evaluate their construct validity when implemented in a virtual reality (VR) simulation.MethodsIn study 1, the metrics for a reference approach to an MT procedure fo

APA, Harvard, Vancouver, ISO, and other styles

39

Duncan, E. M., C. R. Casey, B. M. Duncan, and J. V. Lloyd. "Effect of Concentration of Trisodium Citrate Anticoagulant on Calculation of the International Normalised Ratio and the International Sensitivity Index of Thromboplastin." Thrombosis and Haemostasis 72, no. 01 (1994): 084–88. http://dx.doi.org/10.1055/s-0038-1648816.

Full text

Abstract:

SummaryThe aim of this study was to determine whether the concentration of trisodium citrate used to anticoagulate blood has an effect on the INR of the sample and the ISI of the thromboplastin. Five thromboplastins including and Australian reference material were used to measure the prothrombin time of normal and patient samples collected into two concentrations of trisodium citrate - 109 mM and 129 mM. There was no effect of citrate concentration on the INRs determined with the reference material. However for the other four thromboplastins there was a significant difference between INRs for

APA, Harvard, Vancouver, ISO, and other styles

40

Rombouts, Eva K., Frits R. Rosendaal, and Felix J. M. van der Meer. "Subtherapeutic oral anticoagulant therapy: Frequency and risk factors." Thrombosis and Haemostasis 101, no. 03 (2009): 552–56. http://dx.doi.org/10.1160/th08-09-0626.

Full text

Abstract:

SummarySubtherapeutic anticoagulation levels increase both the risk and severity of thromboembolism. The aim of this study was to determine the cumulative incidence of subtherapeutic international normalised ratios (INRs) and to identify risk factors associated with a low INR. We performed a cohort study in 7,419 patients from a Dutch anticoagulation clinic. Patients who started a first treatment with oral anticoagulants between January 2000 and December 2005 and who were stably anticoagulated (4 consecutive INRs in the therapeutic range) were included. Within the cohort a nested case control

APA, Harvard, Vancouver, ISO, and other styles

41

Chin-Yee, Ian, Michael Kovacs, Alejandro Lazo-Langner, Michael Keeney, Cyrus Hsia, and Christopher Patriquin. "Study of Octaplex dosing accuracy: An in vitro analysis." Thrombosis and Haemostasis 107, no. 02 (2012): 248–52. http://dx.doi.org/10.1160/th11-09-0610.

Full text

Abstract:

SummaryProthrombin complex concentrates (PCC) are recommended for urgent warfarin reversal. However, disagreement exists regarding the proper dosing strategy (i.e. fixed vs. weight-based). We measured the in vitro effect of PCC dosing on international normalised ratio (INR) and factor activity. Plasma from warfarin-anticoagulated patients with stable INRs was collected. PCC doses of 1,000, 2,000 and 3,000 IU were added to the samples, and INR and factor activity were analysed before and after PCC. Twenty-three of thirty subjects enrolled had complete data for analysis. INRs were below 1.5 in a

APA, Harvard, Vancouver, ISO, and other styles

42

Foster, Andrew W., Rafael Pernil, Carl J. Patterson, and Nigel J. Robinson. "Metal specificity of cyanobacterial nickel-responsive repressor InrS: cells maintain zinc and copper below the detection threshold for InrS." Molecular Microbiology 92, no. 4 (2014): 797–812. http://dx.doi.org/10.1111/mmi.12594.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Asari, Kazuhiko, and Harumi Takahashi. "Prediction of the impact of CYP2C9 and VKORC1 genotypes on warfarin–sorafenib interactions in whites and Asians." Pharmacogenomics 21, no. 12 (2020): 853–62. http://dx.doi.org/10.2217/pgs-2020-0036.

Full text

Abstract:

Aim: To predict the impact of the different CYP2C9 and VKORC1 genotypes on warfarin–sorafenib interactions in whites and Asians. Materials & methods: The influences of the CYP2C9*1/*3 and VKORC1 -1639 A/A genotypes on increases in anticoagulation responses (international normalized ratio [INR]) in the presence of sorafenib were predicted using the population pharmacokinetic/pharmacodynamic (PK/PD) model in whites and Asians. Results: INRs were predicted to be 2.0–2.1- versus 1.8–1.9-times higher in the presence of sorafenib in the CYP2C9 ( *1/*1 vs *1/*3) groups than those for warfarin alo

APA, Harvard, Vancouver, ISO, and other styles

44

Kovalevskiy, Evgeny V. "EPICOH-2021 — International Symposium on Epidemiology in Occupational Health." Russian Journal of Occupational Health and Industrial Ecology 61, no. 11 (2021): 755–57. http://dx.doi.org/10.31089/1026-9428-2021-61-11-755-757.

Full text

Abstract:

From October 25 to 28, 2021, Canada hosted the 28th EPICOH Symposium 2021, organized by the Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST) and the Institut national de la recherche scientifique (INRS)

APA, Harvard, Vancouver, ISO, and other styles

45

Boughman, Lori, Marilyn M. Rymer, Maureen Knell, Cathy Carroll, and Duane Thrutchley. "Outpatient Low-Molecular Weight Heparin for Conversion to Warfarin in Non-Valvular Atrial Fibrillation." Stroke 32, suppl_1 (2001): 377. http://dx.doi.org/10.1161/str.32.suppl_1.377.

Full text

Abstract:

P206 Background: Patients with non-valvular atrial fibrillation (NVAF) are often hospitalized on IV heparin until target INRs are achieved. SQ LMWH has been shown to be safe and effective for OP treatment of DVT, but has not been widely used in NVAF. We discharged 35 patients with NVAF on SQ LMWH and analyzed safety, cost and satisfaction. Methods: Patients with NVAF who were being held in the hospital only for conversion of heparin to warfarin and who met other entry criteria were enrolled. Baseline CBC, coagulation profile, neurologic exam and demographic data were obtained. Patients were in

APA, Harvard, Vancouver, ISO, and other styles

46

Barchi, Elia, and Francesco Musiani. "Molecular Modelling of the Ni(II)-Responsive Synechocystis PCC 6803 Transcriptional Regulator InrS in the Metal Bound Form." Inorganics 7, no. 6 (2019): 76. http://dx.doi.org/10.3390/inorganics7060076.

Full text

Abstract:

InrS (internal nickel-responsive sensor) is a transcriptional regulator found in cyanobacteria that represses the transcription of the nickel exporter NrsD in the apo form and de-represses expression of the exporter upon Ni(II) binding. Although a crystal structure of apo-InrS from Synechocystis PCC 6803 has been reported, no structure of the protein with metal ions bound is available. Here we report the results of a computational study aimed to reconstruct the metal binding site by taking advantage of recent X-ray absorption spectroscopy (XAS) data and to envisage the structural rearrangement

APA, Harvard, Vancouver, ISO, and other styles

47

Trilli, Lauren E., Catherine L. Kelley, Sherrie L. Aspinall, and Beverly A. Kroner. "Potential Interaction between Warfarin and Fluvastatin." Annals of Pharmacotherapy 30, no. 12 (1996): 1399–402. http://dx.doi.org/10.1177/106002809603001207.

Full text

Abstract:

OBJECTIVE: To report three cases of a suspected interaction between warfarin and fluvastatin. CASE SUMMARIES: Three patients receiving stable warfarin dosages with therapeutic international normalized ratios (INRs) exhibited increased INRs when fluvastatin was added to their maintenance regimens. While none of the patients experienced a bleeding episode, they did require a reduction in their weekly warfarin dosage to achieve an appropriate level of anticoagulation. DISCUSSION: Reports of an interaction between warfarin and lovastatin have been described previously; however, to our knowledge, t

APA, Harvard, Vancouver, ISO, and other styles

48

O’Shaughnessy, Douglas, Zhishon Li, and Azarshid Farhat. "Recent progress in the INRS speech recognition system." Journal of the Acoustical Society of America 98, no. 5 (1995): 2986. http://dx.doi.org/10.1121/1.413924.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

O’Shaughnessy, Douglas D., Zhishun Li, Azarshid Farhat, Rachida El Meliani, Rivarol Vergin, and Michel Héon. "Recent progress in the INRS speech recognition system." Journal of the Acoustical Society of America 100, no. 4 (1996): 2757. http://dx.doi.org/10.1121/1.416329.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

O’Shaughnessy, Douglas D., Clark Z. Lee, Christophe Savariaux, et al. "Recent progress in the INRS speech recognition system." Journal of the Acoustical Society of America 101, no. 5 (1997): 3201. http://dx.doi.org/10.1121/1.419361.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!