Academic literature on the topic 'Insecticides; Mosquitoes'

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Journal articles on the topic "Insecticides; Mosquitoes"

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Andriessen, Rob, Janneke Snetselaar, Remco A. Suer, Anne J. Osinga, Johan Deschietere, Issa N. Lyimo, Ladslaus L. Mnyone, et al. "Electrostatic coating enhances bioavailability of insecticides and breaks pyrethroid resistance in mosquitoes." Proceedings of the National Academy of Sciences 112, no. 39 (August 31, 2015): 12081–86. http://dx.doi.org/10.1073/pnas.1510801112.

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Insecticide resistance poses a significant and increasing threat to the control of malaria and other mosquito-borne diseases. We present a novel method of insecticide application based on netting treated with an electrostatic coating that binds insecticidal particles through polarity. Electrostatic netting can hold small amounts of insecticides effectively and results in enhanced bioavailability upon contact by the insect. Six pyrethroid-resistant Anopheles mosquito strains from across Africa were exposed to similar concentrations of deltamethrin on electrostatic netting or a standard long-lasting deltamethrin-coated bednet (PermaNet 2.0). Standard WHO exposure bioassays showed that electrostatic netting induced significantly higher mortality rates than the PermaNet, thereby effectively breaking mosquito resistance. Electrostatic netting also induced high mortality in resistant mosquito strains when a 15-fold lower dose of deltamethrin was applied and when the exposure time was reduced to only 5 s. Because different types of particles adhere to electrostatic netting, it is also possible to apply nonpyrethroid insecticides. Three insecticide classes were effective against strains of Aedes and Culex mosquitoes, demonstrating that electrostatic netting can be used to deploy a wide range of active insecticides against all major groups of disease-transmitting mosquitoes. Promising applications include the use of electrostatic coating on walls or eave curtains and in trapping/contamination devices. We conclude that application of electrostatically adhered particles boosts the efficacy of WHO-recommended insecticides even against resistant mosquitoes. This innovative technique has potential to support the use of unconventional insecticide classes or combinations thereof, potentially offering a significant step forward in managing insecticide resistance in vector-control operations.
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Gourley, Stephen A., Rongsong Liu, and Jianhong Wu. "Slowing the evolution of insecticide resistance in mosquitoes: a mathematical model." Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 467, no. 2132 (January 19, 2011): 2127–48. http://dx.doi.org/10.1098/rspa.2010.0413.

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A big problem in malaria control is the rapidity with which mosquitoes can develop resistance to insecticides. The possibility of creating evolution-proof insecticides is therefore of considerable interest. Biologists have suggested that effective malaria control, with only weak selection for insecticide resistance, could be achieved if insecticides target only old mosquitoes that have already laid most of their eggs. The strategy aims to exploit the fact that most malarial mosquitoes do not live long enough to transmit the disease. We derive, analyse and compare two mathematical models, one for an insecticide that kills on exposure, and the other for an insecticide that targets only older mosquitoes. Both models predict that insecticide-resistant mosquitoes will become dominant over time but, very importantly, this occurs on a very much slower time scale when the insecticide only affects older mosquitoes. We present analytical results on linear and global stability of the non-trivial equilibrium in which only the resistant mosquito strain is present, together with a theorem comparing the rates of convergence for the two models. Numerical simulations show that the effect of targeting only old mosquitoes on the evolution of resistance is dramatic.
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N’Dri, Bédjou P., Kathrin Heitz-Tokpa, Mouhamadou Chouaïbou, Giovanna Raso, Amoin J. Koffi, Jean T. Coulibaly, Richard B. Yapi, Pie Müller, and Jürg Utzinger. "Use of Insecticides in Agriculture and the Prevention of Vector-Borne Diseases: Population Knowledge, Attitudes, Practices and Beliefs in Elibou, South Côte d’Ivoire." Tropical Medicine and Infectious Disease 5, no. 1 (March 1, 2020): 36. http://dx.doi.org/10.3390/tropicalmed5010036.

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People’s knowledge, attitudes, practices and beliefs (KAPB) pertaining to malaria are generally well described. However, little is known about population knowledge and awareness of insecticide resistance in malaria vectors. The aim of this study was to investigate KAPB related to insecticide resistance in malaria vectors due to the use of insecticides in agriculture and the prevention against mosquitoes. In mid-2017, we carried out a cross-sectional survey in Elibou, South Côte d’Ivoire, employing a mixed methods approach. Quantitative data were obtained with a questionnaire addressed to household heads. Interviews were conducted with key opinion leaders, including village chiefs, traditional healers, heads of health centres and pesticide sellers. Focus group discussions were conducted with youth and elders. A total of 203 individuals participated in the questionnaire survey (132 males, 65%). We found that people had good knowledge about malaria and mosquitoes transmitting the disease, while they felt that preventing measures were ineffective. Pesticides were intensively used by farmers, mainly during the rainy season. Among the pesticides used, insecticides and herbicides were most commonly used. While there was poor knowledge about resistance, the interviewees stated that insecticides were not killing the mosquitoes anymore. The main reason given was that insecticides were diluted by the manufacturers as a marketing strategy to sell larger quantities. More than a third of the farmers used agricultural pesticides for domestic purposes to kill weeds or mosquitoes. We observed a misuse of pesticides among farmers, explained by the lack of specific training. In the community, long-lasting insecticidal nets were the most common preventive measure against malaria, followed by mosquito coils and insecticide sprays. The interviewees felt that the most effective way of dealing with insecticide resistance was to combine at least two preventive measures. In conclusion, population attitudes and practices related to insecticides used in agriculture and the prevention against mosquitoes could lead to resistance in malaria vectors, while people’s knowledge about insecticide resistance was limited. There is a need to raise awareness in communities about the presence of resistance in malaria vectors and to involve them in resistance management.
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David, Jean-Philippe, Hanafy Mahmoud Ismail, Alexia Chandor-Proust, and Mark John Ingraham Paine. "Role of cytochrome P450s in insecticide resistance: impact on the control of mosquito-borne diseases and use of insecticides on Earth." Philosophical Transactions of the Royal Society B: Biological Sciences 368, no. 1612 (February 19, 2013): 20120429. http://dx.doi.org/10.1098/rstb.2012.0429.

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The fight against diseases spread by mosquitoes and other insects has enormous environmental, economic and social consequences. Chemical insecticides remain the first line of defence but the control of diseases, especially malaria and dengue fever, is being increasingly undermined by insecticide resistance. Mosquitoes have a large repertoire of P450s (over 100 genes). By pinpointing the key enzymes associated with insecticide resistance we can begin to develop new tools to aid the implementation of control interventions and reduce their environmental impact on Earth. Recent technological advances are helping us to build a functional profile of the P450 determinants of insecticide metabolic resistance in mosquitoes. Alongside, the cross-responses of mosquito P450s to insecticides and pollutants are also being investigated. Such research will provide the means to produce diagnostic tools for early detection of P450s linked to resistance. It will also enable the design of new insecticides with optimized efficacy in different environments.
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Luan, Kun, Andre J. West, Marian G. McCord, Emiel A. DenHartog, Quan Shi, Isa Bettermann, Jiayin Li, et al. "Mosquito-Textile Physics: A Mathematical Roadmap to Insecticide-Free, Bite-Proof Clothing for Everyday Life." Insects 12, no. 7 (July 13, 2021): 636. http://dx.doi.org/10.3390/insects12070636.

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Garments treated with chemical insecticides are commonly used to prevent mosquito bites. Resistance to insecticides, however, is threatening the efficacy of this technology, and people are increasingly concerned about the potential health impacts of wearing insecticide-treated clothing. Here, we report a mathematical model for fabric barriers that resist bites from Aedes aegypti mosquitoes based on textile physical structure and no insecticides. The model was derived from mosquito morphometrics and analysis of mosquito biting behavior. Woven filter fabrics, precision polypropylene plates, and knitted fabrics were used for model validation. Then, based on the model predictions, prototype knitted textiles and garments were developed that prevented mosquito biting, and comfort testing showed the garments to possess superior thermophysiological properties. Our fabrics provided a three-times greater bite resistance than the insecticide-treated cloth. Our predictive model can be used to develop additional textiles in the future for garments that are highly bite resistant to mosquitoes.
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Hareem Sajjad and Neelam Arif. "Biological Control of Mosquito Vectors." Scientific Inquiry and Review 3, no. 1 (January 31, 2019): 25–32. http://dx.doi.org/10.32350/sir.31.03.

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The main purpose of this review paper is to study different biological control methods for controlling mosquito vectors. Mosquitoes act as vector for many harmful diseases including malaria, dengue fever, yellow fever, filarial, encephalitis, chikungunya, dengue and poly arthritis. The use of chemical insecticides for controlling mosquitoes is limited because they develop resistance against these insecticides. So, efforts have been made to control the mosquito vectors by eco-friendly techniques. At present, biocontrol agents are used to control the mosquito species with the aim to reduce the impact and cost of insecticide based strategies. These biocontrol agents involve the use of natural enemies including bacteria, fungi, larvivorous fish, protozoans and nematodes. These agents target mosquitoes at different stages of their life cycle. In this paper, we focus on several bio-controlling methods used to reduce the population of mosquito vectors.
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Yanuar, Firda, and Willem Sugiharto. "Efikasi Insektisida Gokilath-S50EC (d,d-transsifenotrin 50 g/l) terhadap Nyamuk Aedes aegypti dengan Metode Pengabutan (Thermal Fogging)." ASPIRATOR - Journal of Vector-borne Disease Studies 10, no. 2 (December 10, 2018): 73–82. http://dx.doi.org/10.22435/asp.v10i2.187.

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Dengue vector control is still relying on fogging using insecticides with solar solvents. This causes pollution due to the odors generated and residues left in the environment. It is necessary to look for alternative insecticides that no longer use solar as a solvent but use water such as Gokilath-S50EC. In this experiment, we tested the effectiveness of Gokilath-S50EC (d,d-trans-syphenotrin 50 g/l) with the aim to see the insecticidal efficacy of Aedes aegypti known as DHF vector. The sample test mosquito used is Ae. aegypti which comes from Pangandaran Lokalitbangkes as many as 25 females. Test mosquitoes were exposed to insecticides for 3-5 seconds with a method of fogging. The experimental results showed that mosquitoes tested fainting in the first 30 seconds after exposure to insecticides. The same results were shown when the solvent was added polyethylene-glycol (PEG). This time trial also measured droplet diameters at 1.0 mm and 1.2 mm nozzle with or without PEG. The test results showed that PEG increased the percentage of droplets of ≥ 50 µm in air and made the insecticide reach even further. Gokilath-S50EC insecticides are effective in killing Ae. aegypti by using water solvents, the addition of PEG will increase the reach of insecticides but not affect the effectiveness of insecticides.
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Weedall, Gareth D., Leon M. J. Mugenzi, Benjamin D. Menze, Magellan Tchouakui, Sulaiman S. Ibrahim, Nathalie Amvongo-Adjia, Helen Irving, et al. "A cytochrome P450 allele confers pyrethroid resistance on a major African malaria vector, reducing insecticide-treated bednet efficacy." Science Translational Medicine 11, no. 484 (March 20, 2019): eaat7386. http://dx.doi.org/10.1126/scitranslmed.aat7386.

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Metabolic resistance to insecticides such as pyrethroids in mosquito vectors threatens control of malaria in Africa. Unless it is managed, recent gains in reducing malaria transmission could be lost. To improve monitoring and assess the impact of insecticide resistance on malaria control interventions, we elucidated the molecular basis of pyrethroid resistance in the major African malaria vector, Anopheles funestus. We showed that a single cytochrome P450 allele (CYP6P9a_R) in A. funestus reduced the efficacy of insecticide-treated bednets for preventing transmission of malaria in southern Africa. Expression of key insecticide resistance genes was detected in populations of this mosquito vector throughout Africa but varied according to the region. Signatures of selection and adaptive evolutionary traits including structural polymorphisms and cis-regulatory transcription factor binding sites were detected with evidence of selection due to the scale-up of insecticide-treated bednet use. A cis-regulatory polymorphism driving the overexpression of the major resistance gene CYP6P9a allowed us to design a DNA-based assay for cytochrome P450–mediated resistance to pyrethroid insecticides. Using this assay, we tracked the spread of pyrethroid resistance and found that it was almost fixed in mosquitoes from southern Africa but was absent from mosquitoes collected elsewhere in Africa. Furthermore, a field study in experimental huts in Cameroon demonstrated that mosquitoes carrying the resistance CYP6P9a_R allele survived and succeeded in blood feeding more often than did mosquitoes that lacked this allele. Our findings highlight the need to introduce a new generation of insecticide-treated bednets for malaria control that do not rely on pyrethroid insecticides.
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Balabanidou, Vasileia, Mary Kefi, Michalis Aivaliotis, Venetia Koidou, Juan R. Girotti, Sergio J. Mijailovsky, M. Patricia Juárez, et al. "Mosquitoes cloak their legs to resist insecticides." Proceedings of the Royal Society B: Biological Sciences 286, no. 1907 (July 17, 2019): 20191091. http://dx.doi.org/10.1098/rspb.2019.1091.

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Malaria incidence has halved since the year 2000, with 80% of the reduction attributable to the use of insecticides. However, insecticide resistance is now widespread, is rapidly increasing in spectrum and intensity across Africa, and may be contributing to the increase of malaria incidence in 2018. The role of detoxification enzymes and target site mutations has been documented in the major malaria vector Anopheles gambiae ; however, the emergence of striking resistant phenotypes suggests the occurrence of additional mechanisms. By comparing legs, the most relevant insect tissue for insecticide uptake, we show that resistant mosquitoes largely remodel their leg cuticles via enhanced deposition of cuticular proteins and chitin, corroborating a leg-thickening phenotype. Moreover, we show that resistant female mosquitoes seal their leg cuticles with higher total and different relative amounts of cuticular hydrocarbons, compared with susceptible ones. The structural and functional alterations in Anopheles female mosquito legs are associated with a reduced uptake of insecticides, substantially contributing to the resistance phenotype.
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Sadia, Christabelle G., France-Paraudie A. Kouadio, Behi K. Fodjo, Sebastien K. Oyou, Adepo-Gourene A. Beatrice, Benjamin G. Koudou, and Chouaïbou S. Mouhamadou. "Short-term metabolic resistance inductive effect of different agrochemical groups on Anopheles gambiae mosquitoes." Wellcome Open Research 6 (June 11, 2021): 147. http://dx.doi.org/10.12688/wellcomeopenres.16876.1.

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Background: In order to assess the impact of the different groups of agricultural pesticides used in Côte d'Ivoire on the increase of mosquitoes resistance to insecticides, the expression profiles of 7 P450 cytochromes and one GSTE2 of Anopheles gambiae involved in mosquito resistance to insecticides were studied. The goal of this study was to determine the effect of short exposure of mosquito larvae to different groups of agricultural pesticides on mosquito resistance. Methods: Three groups of pesticides were selected: (i) agricultural insecticide solutions, (ii) none-insecticide pesticide solutions (a mixture of herbicides and fungicides), and (iii) a mixture of the first two. A fourth non-pesticide solution was used as a control. Four groups of each stage 2 larvae (strain Kisumu, male and female) were exposed to 20% concentrated solution for 24 hours. Susceptibility tests for dichlorodiphenyltrichloroethane (DDT) and Deltamethrin were carried out on adults aged 2-5 days. Quantitative reverse transcription polymerase chain reaction (RT-qPCR) was performed to quantify the expression of eight metabolic genes involved in mosquito resistance to insecticides. Results: Susceptibility to DDT showed a similar increase in the time required to knock down 50% of mosquitoes (kdt50) in l colonies exposed to insecticides and none-insecticides compared to the control colony. As for deltamethrin, kdt50 was higher in the colonies exposed to insecticides and the pesticide mixture compared to the colony exposed to none-insecticides. Of all the genes studied in all colonies, except for CYP6P1 induced only in the colony consisting of the pesticide mixture, no genes were induced. Conclusions: This study confirmed that induction is influenced by the duration, the concentration of the solution and the type of xenobiotic used as an inducer. The overexpression of CYP6P1 confirmed the inductive effect that a short exposure of mosquito larvae to agricultural pesticides could have.
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Dissertations / Theses on the topic "Insecticides; Mosquitoes"

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Davis, Ryan Scott. "An ecological risk assessment for mosquito insecticides." Thesis, Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/davis/DavisR0507.pdf.

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Malima, Robert Chikoja Munyu. "Evaluation of long lasting insecticidal materials and treatment kits and control of pyrethroid insecticide resistant mosquitoes using alternative insecticides on nets." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.536834.

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Buss, David Shaun. "P-glycoprotein and the toxicity of insecticides to mosquitoes." Thesis, University of Reading, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413877.

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Vatandoost, Hassan. "The functional basis of pyrethroid resistance in the malaria vector, Anopheles stephensi." Thesis, University of Liverpool, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318278.

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Hossain, Md Ismail. "Effect of impregnated nets on mortality and behaviour of mosquitoes." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340893.

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Kasim, Siti Hawa. "Factors affecting the rotational use of insecticides for the management of resistance in mosquitoes." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1992. http://researchonline.lshtm.ac.uk/1831256/.

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The rotation of the use of chemically unrelated insecticides has been advocated to delay the build up of resistance. To examine this concept in the laboratory, Anopheles albimanus and Culex guinquefasciatus were subjected to two kinds of rotational selection which may be referred to as short term pre-planned rotation and "opportunistic" rotation. No difference was observed between these two methods in term of the time for each resistance level to reach 5Q%. The effectiveness of selection for resistance depends on the protection conferred by resistance genes and this was tested by laboratory releases of the DDT resistant and susceptible homozygotes and heterozygotes of An. gambiae into DDT sprayed and unsprayed miniature huts. All the genotypes were killed with freshly applied DDT but survivors were observed from month 2, 3 and 5 onwards for RR, RS and SS genotypes, respectively. Persistence of DDT on the sprayed wall and roof of the mud hut was studied by bioassays and biochemical assays on scrapings from the wall and roof. Linkage between resistance genes could effect the rotational use of insecticides. No linkage was found between propoxur and dieldrin resistance genes by combining bioassay and biochemical methods. As a preparation for a field studies in Malaysian field collected Aedes aegypti and Culex guinguefasciatus larvae were selected with temephos and Bti. Cx guinguefasciatus responded to temephos selection but Ae. aegypti did not respond to temephos and neither species responded to Bti selection. ~ Caged adults were exposed to thermal fogging in the field. The partially resistant Cx guinguefasciatus strain hardly survived any better than susceptible strains. Resistant and susceptible larvae were exposed to water samples from containers which had been treated with temephos sand granules. 100% mortality was obtained for all the strains up to week 6. Resistant Culex started to survive at week 7 but susceptibles did not do so until week ten. The prospects for the various proposed strategies for resistance management are discussed.
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Asidi, Alex Ndongidila. "Evaluation of nets treated with alternative insecticides against pyrethroid resistant mosquitoes and pyrethroid tolerant bedbugs." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411599.

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Russell, Brenda Lurline. "Factors preventing the metabolism of carbohydrates by Bacillus sphaericus 2362." Thesis, Virginia Tech, 1988. http://hdl.handle.net/10919/45179.

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Bacillus sphaericus 2362 is a mosquito pathogenic bacterium. Its greatest industrial potential may be in developing countries where mosquitos are often vectors for diseases. This strain is typical of the species in that it is unable to grow using carbohydrates as a sole source of carbon. The goal of this research was to determine the metabolic deficiency(s) responsible for the inability of this organism to grow on carbohydrates. Compounds that supported light growth of this organism on an agar-solidified, defined medium included acetate, glycerol, and gluconate. Growth in a defined liquid medium with acetate as the source of carbon was much slower than growth in a complex, protein-based broth. B. sphaericus grew poorly in a defined, liquid medium with glycerol or gluconate as the carbon source. Activity of enzymes responsible for the initiation of metabolism of some substrates was not detected in cell extracts. These enzymes were: glucokinase, hexokinase, beta-galactosidase, and amylase. Growth of this bacterium on glycerol as a sole source of carbon implies the presence of the enzymes from the lower half of the Embden-Meyerhof-Parnas (EMP) pathway. Two enzymes of the upper half of the EMF pathway, phosphofructokinase and fructose diphosphate aldolase, were undetected in cell extracts. In addition, glucose dehydrogenase activity was not detected. The inability to form glucose-6-phosphate from glucose prevents the catabolism of this and related substrates via the Entner-Doudoroff (ED), hexose monophosphate (HMP), and EMF pathways. Oxygen uptake studies indicated that B. sphaericus oxidized gluconate slightly but only when the cells were grown in a complex, protein-based medium supplemented with gluconate. Although gluconokinase activity was detected in cell extracts, no activity was detected for the key enzymes of the ED (phosphogluconate dehydratase/KDPG aldolase), or HMP (6-phosphogluconate dehydrogenase) pathway. It is unclear how B. sphaericus grows on a defined medium with gluconate as the sole source of carbon. In addition to enzymatic deficiencies, whole cells were unable to accumulate [¹⁴C]glucose or [¹⁴C]sucrose.
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Engdahl, Cecilia. "Selective inhibition of acetylcholinesterase 1 from disease-transmitting mosquitoes : design and development of new insecticides for vector control." Doctoral thesis, Umeå universitet, Kemiska institutionen, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-134625.

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Acetylcholinesterase (AChE) is an essential enzyme with an evolutionary conserved function: to terminate nerve signaling by rapid hydrolysis of the neurotransmitter acetylcholine. AChE is an important target for insecticides. Vector control by the use of insecticide-based interventions is today the main strategy for controlling mosquito-borne diseases that affect millions of people each year. However, the efficiency of many insecticides is challenged by resistant mosquito populations, lack of selectivity and off-target toxicity of currently used compounds. New selective and resistance-breaking insecticides are needed for an efficient vector control also in the future. In the work presented in this thesis, we have combined structural biology, biochemistry and medicinal chemistry to characterize mosquito AChEs and to develop selective and resistance-breaking inhibitors of this essential enzyme from two disease-transmitting mosquitoes.We have identified small but important structural and functional differences between AChE from mosquitoes and AChE from vertebrates. The significance of these differences was emphasized by a high throughput screening campaign, which made it evident that the evolutionary distant AChEs display significant differences in their molecular recognition. These findings were exploited in the design of new inhibitors. Rationally designed and developed thiourea- and phenoxyacetamide-based non-covalent inhibitors displayed high potency on both wild type and insecticide insensitive AChE from mosquitoes. The best inhibitors showed over 100-fold stronger inhibition of mosquito than human AChE, and proved insecticide potential as they killed both adult and larvae mosquitoes.We show that mosquito and human AChE have different molecular recognition and that non-covalent selective inhibition of AChE from mosquitoes is possible. We also demonstrate that inhibitors can combine selectivity with sub-micromolar potency for insecticide resistant AChE.
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Poupardin, Rodolphe. "Interactions gènes-environnement chez les moustiques et leur impact sur la résistance aux insecticides." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00583441.

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Les moustiques génèrent une nuisance importante et sont notamment contrôlés grâce à des traitements insecticides. Aujourd'hui, les gîtes où se développent leurs larves sont souvent pollués par des xénobiotiques environnementaux (hydrocarbures, herbicides, pesticides, toxines naturelles...). Jusqu'à présent, l'impact de ces xénobiotiques sur la capacité des larves de moustiques à résister aux insecticides chimiques reste méconnu. Cette thèse vise à étudier la réponse des larves de d'Aedes aegypti aux xénobiotiques environnementaux et leur impact sur leur tolérance et résistance aux insecticides chimiques. Une première étude, sur le court terme, montre que des larves exposées pendant 24h à divers xénobiotiques deviennent plus tolérantes à vis à vis de différents insecticides chimiques (Poupardin et al. 2008). Des études biochimiques et transcriptomiques suggèrent que l'induction de certaines familles d'enzymes (e.g. P450s et GSTs) par ces xénobiotiques peut être liée à l'augmentation de tolérance des larves vis-à-vis de l'insecticide. Dans le but de mieux caractériser le profil transcriptionnel des précédents gènes candidats, des expérimentations complémentaires ont été faites à différents niveaux (Poupardin et al., 2010). Cette étude a montré que de nombreux gènes étaient préférentiellement transcrits dans des tissus fortement impliqués dans la détoxication de composés exogènes, essentiellement des CYP6. Elle révèle aussi que la transcription de ces P450s varie beaucoup au cours des différents stades de développement et qu'ils étaient induits à des faibles de doses de polluants avec un pic d'induction après 48 et 72 heures d'exposition. Ces études mettent en évidence le rôle potentiel des gènes de détoxication dans la réponse à l'exposition à des xénobiotiques et dans l'augmentation de tolérance aux insecticides chimiques. Concernant l'étude sur le long terme de l'impact des polluants sur la résistance des moustiques aux insecticides, la question est de savoir si les polluants trouvés dans l'environnement influencent la sélection de la résistance aux insecticides et si oui, favorisent-ils la sélection de gènes en particulier? Pour répondre à ces questions, trois souches d'Aedes aegypti ont été sélectionnées à la perméthrine. Ces souches sont exposées ou non à différents polluants avant sélection. Après 10 générations de sélection, des bioessais montrent une résistance de ces 3 souches vis-à-vis de la perméthrine. Aucune différence significative de niveau de résistance n'est observée entre les trois souches sélectionnées pour le moment. Pour identifier les gènes différentiellement transcrits dans ces souches, la puce "Agilent Aedes chip" développée par l'école de médecine tropicale de Liverpool (LSTM) et contenant 14200 transcrits a été utilisée. Les microarrays ont révélé que la présence de polluants ou insecticides résiduels pouvait affecter la sélection des mécanismes de résistance aux insecticides chimiques, notamment par la sélection de gènes particuliers codant pour des enzymes de détoxication (Poupardin et al, en préparation). D'une manière globale, cette thèse permettra de mieux comprendre l'impact de l'environnement chimique sur la résistance des moustiques aux insecticides et fournira de nouvelles pistes afin d'optimiser les traitements insecticides utilisés en démoustication.
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Books on the topic "Insecticides; Mosquitoes"

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Khan, Shane. Who uses insecticide-treated mosquito nets?: A comparison of seven countries in Sub-Saharan Africa. Calverton, MD: Macro International, 2008.

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Bakote'e, Bernard. Insecticide treated mosquito nets: The Solomon Islands experience. Solomon Islands: [s.n.], 1997.

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Division, Montana Environmental Management. Mosquito control training manual. Helena, Mont: The Division, 1986.

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La lutte contre les moustiques nuisants et vecteurs de maladies: L'évaluation de nouveaux insecticides utilisables contre les moustiques en Afrique tropicale. Paris: Ed. Karthala, 1998.

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Johnson, Art. Methoprene concentrations in surface water samples from Grant County Mosquito Control District No. 1. Olympia, WA: Washington State Dept. of Ecology, 2006.

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Rwanda Biomedical Center. Malaria & Other Parasitic Diseases Division. Guidelines for the supply, distribution and management of long lasting insecticide treated nets (LLINs) in Rwanda: Amabwiliza arebana no kohereza inzitiramibu kumavuriro, imicungire yazo, n'uko zitangwa. Kigali: rbc, Rwanda Biomedical Center, Malaria & Other Parasitic Diseases Division, 2010.

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Coalition Against Malaria in Ethiopia. Effect of a combined use of mosquito repellent and insecticide treated net on malaria prevalence in southern Ethiopia: A cluster randomized controlled trial. Addis Ababa, Ethiopia: Malaria Consortium Ethiopia, 2009.

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Washington (State). Dept. of Ecology. Water Quality Program., ed. Best management practices for mosquito control. Olympia, WA: The Dept., 2004.

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Jacqueline, Cattani, Lengeler Christian, Savigny Don de, International Development Research Centre (Canada), and World Health Organization, eds. Net gain: A new method for preventing malaria deaths. Ottawa: International Development Research Centre, 1996.

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Naturally Bug-Free: 75 Nontoxic Recipes for Repelling Mosquitoes, Ticks, Fleas, Ants, Moths & Other Pesky Insects. Storey Publishing, LLC, 2016.

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Book chapters on the topic "Insecticides; Mosquitoes"

1

Devillers, James. "Use of Insecticides Indoors for the Control of Mosquitoes." In Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases, 423–52. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.4324/9781315151656-15.

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Devillers, James. "Repurposing Insecticides and Drugs for the Control of Mosquitoes and Their Diseases." In Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases, 1–38. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.4324/9781315151656-1.

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Service, M. W. "Experimental Hut Techniques for Evaluating Insecticides." In Mosquito Ecology, 637–51. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1868-2_8.

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Service, M. W. "Experimental Hut Techniques for Evaluating Insecticides." In Mosquito Ecology, 637–51. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-015-8113-4_8.

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Carnevale, Pierre, and Frédérick Gay. "Insecticide-Treated Mosquito Nets." In Methods in Molecular Biology, 221–32. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9550-9_16.

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Schechtman, Helio, Denise Valle, and Max O. Souza. "Insecticide Resistance: Can We Create Super-Mosquitoes?" In XXVI Brazilian Congress on Biomedical Engineering, 695–98. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-2517-5_106.

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Govindarajan, M. "Mosquito Larvicidal Potential of Medicinal Plants." In Herbal Insecticides, Repellents and Biomedicines: Effectiveness and Commercialization, 25–61. New Delhi: Springer India, 2016. http://dx.doi.org/10.1007/978-81-322-2704-5_3.

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Lacey, Lawrence A., and Richard W. Merritt. "The Safety of Bacterial Microbial Agents Used for Black Fly and Mosquito Control in Aquatic Environments." In Environmental Impacts of Microbial Insecticides, 151–68. Dordrecht: Springer Netherlands, 2003. http://dx.doi.org/10.1007/978-94-017-1441-9_8.

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Paulraj, M. Gabriel, P. Saravana Kumar, S. Ignacimuthu, and D. Sukumaran. "Natural Insecticides from Actinomycetes and Other Microbes for Vector Mosquito Control." In Herbal Insecticides, Repellents and Biomedicines: Effectiveness and Commercialization, 85–99. New Delhi: Springer India, 2016. http://dx.doi.org/10.1007/978-81-322-2704-5_5.

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Faulde, Michael K. "Long-Lasting Insecticide-Treated Textiles Preventing from Mosquito Bite and Mosquito-Borne Diseases." In Parasitology Research Monographs, 281–303. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94075-5_12.

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Conference papers on the topic "Insecticides; Mosquitoes"

1

Frolova, A. I. "RANGE OF DIAGNOSTIC CONCENTRATIONS FROM DIFFERENT GROUPS OF INSECTICIDES IN RELATION TO INVASIVE SPECIES OF MOSQUITOES OF THE GENUS AEDES." In V International Scientific Conference CONCEPTUAL AND APPLIED ASPECTS OF INVERTEBRATE SCIENTIFIC RESEARCH AND BIOLOGICAL EDUCATION. Tomsk State University Press, 2020. http://dx.doi.org/10.17223/978-5-94621-931-0-2020-82.

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Abstract:
Data on the susceptibility to insecticides of various structures in mosquito larvae of Aedes albopictus that is a vector of arboviral fevers are given. Diagnostic concentrations of insecticides for the detection of insecticide resistance in Ae. albopictus populations from different districts of the Russia Black Sea coast of the Caucasus are calculated.
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Brelsfoard, Corey L. "Male mosquitoes as vehicles for insecticide." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.93288.

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Thomé, Roberto Carlos Antunes, Claudia Mazza Dias, Edilson Fernandes Arruda, Dayse Haime Pastore, and Hyun Mo Yang. "Optimal Control of Aedes Aegypti Mosquitoes by Sterile Insect Technique, Insecticide and Larvicide." In XXXVI Iberian Latin American Congress on Computational Methods in Engineering. Rio de Janeiro, Brazil: ABMEC Brazilian Association of Computational Methods in Engineering, 2015. http://dx.doi.org/10.20906/cps/cilamce2015-0072.

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Hozzein, Wael. "INSECTICIDAL ACTIVITIES OF NEWLY ISOLATED ACTINOMYCETES AGAINST THE RIFT VALLEY FEVER MOSQUITO AEDES AEGYPTII." In 29th International Academic Conference, Rome. International Institute of Social and Economic Sciences, 2017. http://dx.doi.org/10.20472/iac.2017.029.013.

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Li, Ting. "The GPCR/G-protein/Adenylyl Cyclase/Protein Kinase A pathway in insecticide resistance of the mosquito, Culex quinquefasciatus." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.115399.

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Susilowati, Rina Priastini, Monica Puspa Sari, and Inggrid Osya Far Far. "Bioassay test of the insecticide synthetic pyrethroid against Aedes aegypti mosquito resistance in three districts of Tangerang city." In THE 8TH ANNUAL BASIC SCIENCE INTERNATIONAL CONFERENCE: Coverage of Basic Sciences toward the World’s Sustainability Challanges. Author(s), 2018. http://dx.doi.org/10.1063/1.5062811.

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Reports on the topic "Insecticides; Mosquitoes"

1

Georghiou, George P. Novel Tests for Rapid Detection of Insecticide Resistance in Mosquito Vectors. Fort Belvoir, VA: Defense Technical Information Center, January 1989. http://dx.doi.org/10.21236/ada206316.

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