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Journal articles on the topic 'Insights and Future Directions'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Kartik Sikha, Vijay, Dayakar Siramgari, and Satyaveda Somepalli. "Infrastructure as Code: Historical Insights and Future Directions." International Journal of Science and Research (IJSR) 12, no. 8 (2023): 2549–58. http://dx.doi.org/10.21275/sr24820064820.

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2

Perry, Laura B., Emma Rowe, and Christopher Lubienski. "School segregation: theoretical insights and future directions." Comparative Education 58, no. 1 (2021): 1–15. http://dx.doi.org/10.1080/03050068.2021.2021066.

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3

Rana, Rashmi, Ravi Kant, Rohit Singh Huirem, Deepika Bohra, and Nirmal Kumar Ganguly. "Omicron variant: Current insights and future directions." Microbiological Research 265 (December 2022): 127204. http://dx.doi.org/10.1016/j.micres.2022.127204.

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4

Rostasy, Kevin. "Neuroinflammation Update: New Insights and Future Directions." Neuropediatrics 44, no. 06 (2013): 295–96. http://dx.doi.org/10.1055/s-0033-1360669.

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5

Lamour, Kurt H., Joe Win, and Sophien Kamoun. "Oomycete genomics: new insights and future directions." FEMS Microbiology Letters 274, no. 1 (2007): 1–8. http://dx.doi.org/10.1111/j.1574-6968.2007.00786.x.

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6

Malacopol, Aretia-Teodora, and Peter Johannes Holst. "Cancer Vaccines: Recent Insights and Future Directions." International Journal of Molecular Sciences 25, no. 20 (2024): 11256. http://dx.doi.org/10.3390/ijms252011256.

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The field of cancer immunotherapy has seen incredible advancements in the past decades. mRNA-based cancer vaccines generating de novo T cell responses, particularly against tumor-specific antigens (TSAs), have demonstrated promising clinical outcomes and overcome diverse challenges. Despite the high potential of neoantigens to provide personalized immunotherapies through their tumor specificity and immunogenicity, challenges related to the scarcity of immunogenic neoepitopes have prompted continuous research towards finding new tumor-associated antigens (TAAs) and broader therapeutic framework

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7

Kim, Tae Won, and Federico Innocenti. "Insights, Challenges, and Future Directions in Irinogenetics." Therapeutic Drug Monitoring 29, no. 3 (2007): 265–70. http://dx.doi.org/10.1097/ftd.0b013e318068623b.

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8

Westergard, Thomas, and Jeffrey D. Rothstein. "Astrocyte Diversity: Current Insights and Future Directions." Neurochemical Research 45, no. 6 (2020): 1298–305. http://dx.doi.org/10.1007/s11064-020-02959-7.

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9

Corlett, Philip R., and Albert R. Powers. "Conditioned hallucinations: historic insights and future directions." World Psychiatry 17, no. 3 (2018): 361–62. http://dx.doi.org/10.1002/wps.20557.

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10

Mariean, Claudia Raluca, Oana Mirela Tiucă, Alexandru Mariean, and Ovidiu Simion Cotoi. "Cancer Cachexia: New Insights and Future Directions." Cancers 15, no. 23 (2023): 5590. http://dx.doi.org/10.3390/cancers15235590.

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Cancer remains a major health problem and is associated with cachexia in up to 80% of cases, leading to decreased survival and quality of life. Cachexia involves complex metabolic disturbances in both protein and energy balance, muscle wasting phenomena, weight loss, systemic inflammation, overall decreased performance status, and tolerability to treatment. The clinical impact of cancer cachexia is very complex, with early detection of cachectic patients and identification of predictive biomarkers being two key factors for improving survival. Thus, a better understanding of the complexity of c

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Stahl, Lea-Sophie, Sonja Ständer, and Claudia Zeidler. "Chronic prurigo: current insights and future directions." Journal of the Egyptian Women's Dermatologic Society 22, no. 2 (2025): 99–105. https://doi.org/10.4103/jewd.jewd_58_24.

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Chronic prurigo (CPG), particularly prurigo nodularis, is a highly burdensome skin disease that is characterized by the presence of chronic pruritus and hyperkeratotic, pruriginous papules and nodules. CPG demands accurate diagnostic and individualized therapeutic strategies. Clinically, CPG is primarily diagnosed through physical examination, assessing the quantity and severity by using validated tools like the Prurigo Activity and Severity score and the Investigator’s Global Assessment. Further diagnosis includes an assessment of the lesion type, underlying causes, comorbidities, and potenti

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12

Mangematin, Vincent, Aurelio M. Ravarini, and Pamela Sharkey Scott. "Practitioner insights on business models and future directions." Journal of Business Strategy 38, no. 2 (2017): 3–5. http://dx.doi.org/10.1108/jbs-10-2016-0130.

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13

Parasa, Sravanthi. "Augmenting colonoscopy with AI: insights and future directions." Lancet Gastroenterology & Hepatology 9, no. 10 (2024): 896–97. http://dx.doi.org/10.1016/s2468-1253(24)00276-0.

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14

Schachter, Asher D., and Terry B. Strom. "Posttransplant Recurrent FSGS: Molecular Insights and Future Directions." Nephron 82, no. 4 (1999): 300–305. http://dx.doi.org/10.1159/000045444.

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15

Lysova, Evgenia I., Bryan J. Dik, Ryan D. Duffy, Svetlana N. Khapova, and Michael B. Arthur. "Calling and careers: New insights and future directions." Journal of Vocational Behavior 114 (October 2019): 1–6. http://dx.doi.org/10.1016/j.jvb.2019.03.004.

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16

Gerhard, Danielle M., and Ronald S. Duman. "Rapid-Acting Antidepressants: Mechanistic Insights and Future Directions." Current Behavioral Neuroscience Reports 5, no. 1 (2018): 36–47. http://dx.doi.org/10.1007/s40473-018-0139-8.

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17

Fock, Kwong Ming, David Y. Graham, and Peter Malfertheiner. "Helicobacter pylori research: historical insights and future directions." Nature Reviews Gastroenterology & Hepatology 10, no. 8 (2013): 495–500. http://dx.doi.org/10.1038/nrgastro.2013.96.

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18

Darfaoui, Mouna, Abdelhamid Elomrani, and Mouna Khouchani. "Esthesioneuroblastoma: Clinical Insights, Therapeutic Strategies, and Future Directions." SAS Journal of Medicine 9, no. 09 (2023): 935–40. http://dx.doi.org/10.36347/sasjm.2023.v09i09.006.

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The management of esthesioneuroblastoma presents unique challenges due to its rarity and complex nature. This malignant tumor originating from the nasal cavities requires a comprehensive and multidisciplinary approach. Our retrospective study focuses on shedding light on the distinctive aspects of managing this uncommon condition based on our experience at the Radiotherapy Oncology Department of Mohammed VI University Hospital in Marrakech, Morocco, over a 6-year period from 2016 to 2021. The majority of the patients in our cohort were male, constituting 60% of the cases, resulting in a male-t

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19

Calderón-Fajardo, Víctor, Sebastian Molinillo, Rafael Anaya-Sánchez, and Yuksel Ekinci. "Brand personality: Current insights and future research directions." Journal of Business Research 166 (November 2023): 114062. http://dx.doi.org/10.1016/j.jbusres.2023.114062.

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20

Büttiker, Pascal, Simon Weissenberger, Martin Anders, Jiri Raboch, George B. Stefano, and Amira Boukherissa. "AlphaFold 2: Insights and Future Directions in Psychiatry." MIND Bulletin on Mind-Body Medicine Research 8 (June 30, 2025): 16–22. https://doi.org/10.61936/themind/202506305.

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Abstract The intricate links between protein misfolding and psychiatric disorders have drawn increasing attention in recent years. Several published studies have highlighted the contributions of misfolded proteins to the pathophysiology of conditions that include schizophrenia, depression, Alzheimer’s disease, and prion diseases. Recent breakthroughs in computational approaches, exemplified by the artificial intelligence application AlphaFold 2, have enabled us to predict protein structures with remarkable precision, resulting in unprecedented insights into the molecular mechanisms driving psy

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21

A.D., Awasare. "Programmable Automation: Future Directions." Recent Trends in Production Engineering 7, no. 2 (2024): 16–20. https://doi.org/10.5281/zenodo.11945677.

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<em>Programmable automation has emerged as a pivotal paradigm in modern industrial systems, offering unparalleled flexibility and efficiency in manufacturing processes. This paper presents a comprehensive review of programmable automation technologies, applications, and future directions. Key topics include programmable logic controllers (PLCs), industrial robots, and computer numerical control (CNC) machines. The review examines advancements in hardware and software, highlighting innovations such as cloud-based automation, cyber-physical systems, and the Internet of Things (IoT). Case studies

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22

Laganà, Antonio Simone. "Management of endometrial cancer: current insights and future directions." Translational Cancer Research 9, no. 12 (2020): 7685–87. http://dx.doi.org/10.21037/tcr-2020-ec-15.

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23

Wu, Claudia Wing-Kwan, and Rashid N. Lui. "Early-onset colorectal cancer: Current insights and future directions." World Journal of Gastrointestinal Oncology 14, no. 1 (2022): 230–41. http://dx.doi.org/10.4251/wjgo.v14.i1.230.

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24

Schwartz, Noa, Ariel D. Stock, and Chaim Putterman. "Neuropsychiatric lupus: new mechanistic insights and future treatment directions." Nature Reviews Rheumatology 15, no. 3 (2019): 137–52. http://dx.doi.org/10.1038/s41584-018-0156-8.

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25

Ruggieri, Martino, Conrad Johanson, and Vincenzo Salpietro. "Pediatric Pseudotumor Cerebri Syndrome: Recent Insights and Future Directions." Journal of Pediatric Neurology 13, no. 01 (2015): 001–2. http://dx.doi.org/10.1055/s-0035-1555143.

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26

Searle, Rosalind H., and Graham Dietz. "Editorial: Trust and HRM: Current insights and future directions." Human Resource Management Journal 22, no. 4 (2012): 333–42. http://dx.doi.org/10.1111/1748-8583.12006.

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27

Logan, Ryan W., Wilbur P. Williams, and Colleen A. McClung. "Circadian rhythms and addiction: Mechanistic insights and future directions." Behavioral Neuroscience 128, no. 3 (2014): 387–412. http://dx.doi.org/10.1037/a0036268.

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28

Melnychuk, Olha, Natalia Opolska, Oleksandr Ostapenko, Serhii Lapshyn, and Andrii Ishchuk. "Utilising mediation for conflict resolution: Insights and future directions." Salud, Ciencia y Tecnología - Serie de Conferencias 3 (August 3, 2024): 1143. http://dx.doi.org/10.56294/sctconf20241143.

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Introduction: in a world increasingly burdened by conflicts, mediation emerges as a vital alternative for resolving disputes. Mediation, involving a neutral mediator aiding parties to reach a mutual agreement, is gaining recognition across various fields such as family, labor, and international disputes. This article explores the application of mediation, the challenges it faces in gaining wider acceptance, and its potential for future expansion.Objectives: to reveal the advantages of mediation over traditional judicial procedures; to identify the obstacles that hinder its widespread implement

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29

Pak, Charles Y. C. "Citrate and Renal Calculi: New Insights and Future Directions." American Journal of Kidney Diseases 17, no. 4 (1991): 420–25. http://dx.doi.org/10.1016/s0272-6386(12)80635-4.

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30

Chaudhuri, Atanu, and Paul Lillrank. "Mass personalization in healthcare: insights and future research directions." Journal of Advances in Management Research 10, no. 2 (2013): 176–91. http://dx.doi.org/10.1108/jamr-05-2013-0033.

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31

Kenny, Paul J. "Reward Mechanisms in Obesity: New Insights and Future Directions." Neuron 69, no. 4 (2011): 664–79. http://dx.doi.org/10.1016/j.neuron.2011.02.016.

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32

Kulik, Thomas J., and Macdonald Dick. "Pediatric cardiovascular intensive care: Current insights and future directions." Progress in Pediatric Cardiology 4, no. 3 (1995): 111–15. http://dx.doi.org/10.1016/1058-9813(95)00119-n.

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33

Wang, L., and R. Weinshilboum. "Thiopurine S-methyltransferase pharmacogenetics: insights, challenges and future directions." Oncogene 25, no. 11 (2006): 1629–38. http://dx.doi.org/10.1038/sj.onc.1209372.

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34

MANN, A., G. THAKUR, V. SHUKLA, and M. GANGULI. "Peptides in DNA delivery: current insights and future directions." Drug Discovery Today 13, no. 3-4 (2008): 152–60. http://dx.doi.org/10.1016/j.drudis.2007.11.008.

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35

Kharabsheh, Buthiena, Hussam Al-Shammari, and Khaled Bataineh. "Research on Corporate Social Responsibility: Insights and Future Directions." Administrative Sciences 13, no. 2 (2023): 64. http://dx.doi.org/10.3390/admsci13020064.

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Our current review paper aims to discuss the various issues pertaining to the future research avenues of CSR, and possible expansions that this scholarly field could have considering the growing interests from numerous academic disciplines and practitioners across the globe. In particular, we briefly discuss the work that has been performed on CSR, major theories that guided this area of research, and a summary of prior research findings. Then, we suggest future directions on specific drivers that motivate firms to engage in CSR activities. Specifically, we provide insights on how research sho

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36

Simões, Kalina, and Jorge Magalhães Rodrigues. "Acupuncture for erectile dysfunction: Insights and future research directions." Revista Internacional de Acupuntura 17, no. 4 (2023): 100269. http://dx.doi.org/10.1016/j.acu.2023.100269.

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37

Zheng, Songyan. "Managing Online Business Complaints: Current Insights and Future Directions." Business and Management Studies 10, no. 1 (2024): 13. http://dx.doi.org/10.11114/bms.v10i1.6813.

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With the development of internet technology and the expansion of the digital economy, online business complaints have increasingly drawn attention from both academia and industry. Despite a growing body of research on online business complaints, there still needs to be more disciplinary perspectives and systematic reviews on this topic. In light of this, this paper adopts a managerial perspective to categorize existing literature into three major areas: online business complaints motivation, factors in causing online business complaint, and online business complaint responses, which clarify th

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38

Lv, Baixue, and Dongdong Zhang. "Targeting CREBRF in Cancer: Mechanistic Insights and Future Directions." Biologics: Targets and Therapy Volume 19 (May 2025): 341–50. https://doi.org/10.2147/btt.s522325.

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39

Irmawati, Irmawati, Syarifuddin Rasyid, and Syamsuddin Syamsuddin. "BIBLIOMETRIC INSIGHTS INTO EARNINGS MANAGEMENT: TRENDS AND FUTURE DIRECTIONS." Jurnal Aplikasi Akuntansi 10, no. 1 (2025): 27–44. https://doi.org/10.29303/jaa.v10i1.671.

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This study presents a bibliometric analysis of earnings management research over 1994–2024, exploring trends, key contributors, and future directions. Using Scopus as the primary database, 1,481 studies were analyzed through VOSviewer and Biblioshiny R to map collaborations, co-citation networks, and thematic evolutions. The findings reveal a 17.79% annual growth rate, with central themes such as corporate governance, discretionary accruals, and audit quality remaining pivotal. Emerging topics, including ESG integration, gender diversity, and the impact of COVID-19, demonstrate the field’s ada

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40

Sana, Nusrat Praween* Sallikim Sangma Tanya Sharma Pankaj Chasta. "Current Insights and Future Directions of Mesenchymal Stem Cell Therapy for Knee Osteoarthritis." International Journal of Pharmaceutical Sciences 2 (December 22, 2024): 2828–52. https://doi.org/10.5281/zenodo.14542927.

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Among the most recent developments in Skillful DDS, gel allows for the dual control of the emulsion's and gel's appearance, making it ideal for a variety of practical applications. Accuracy standards: An oil sorting device utilizing liquid paraffin and propylene glycol, a surfactant consisting of Tween 80 and arrive at 80, and the utilization of pseudo ternary coordinate graphs were utilized in the development of this smaller-than-common emulsion w/o. Using a variety of methods, the high-level emulsion orchestrate was mixed into the gel mixture containing Carbopol-934, HPMC-5, and HPMC15+ Carb

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41

Wingfield Digby, James, Jenny King, Jaclyn Smith, and Paul Marsden. "Future Directions in Chronic Cough." US Respiratory & Pulmonary Diseases 8, no. 1 (2023): 28. http://dx.doi.org/10.17925/usrpd.2023.8.1.28.

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Introduction: Refractory/unexplained chronic cough (RUCC) is a highly prevalent debilitating condition. The characteristics of RUCC suggest neuronal excitability. The biological mechanisms leading to this in humans are uncertain but are thought to involve changes in both the peripheral and central nervous system. Efficacy of P2X purinoceptor 3 (P2X3) antagonists suggests a role for extracellular adenosine triphosphate (ATP) in RUCC. In guinea pigs, ATP release occurs in response to hypotonic saline, through a transient receptor potential cation channel subfamily V member 4 (TRPV4)−ATP−P2X3 axi

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42

Pollack, Ian F., Sameer Agnihotri, and Alberto Broniscer. "Childhood brain tumors: current management, biological insights, and future directions." Journal of Neurosurgery: Pediatrics 23, no. 3 (2019): 261–73. http://dx.doi.org/10.3171/2018.10.peds18377.

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Brain tumors are the most common solid tumors in children, and, unfortunately, many subtypes continue to have a suboptimal long-term outcome. During the last several years, however, remarkable advances in our understanding of the molecular underpinnings of these tumors have occurred as a result of high-resolution genomic, epigenetic, and transcriptomic profiling, which have provided insights for improved tumor categorization and molecularly directed therapies. While tumors such as medulloblastomas have been historically grouped into standard- and high-risk categories, it is now recognized that

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43

Walton, Mat, Emily F. Gates, and Pablo Vidueira. "Insights and future directions for systems and complexity‐informed evaluation." New Directions for Evaluation 2021, no. 170 (2021): 159–71. http://dx.doi.org/10.1002/ev.20459.

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44

Chen, Kai, Chengchen Hu, Xin Zhang, Kai Zheng, Yan Chen, and Athanasios Vasilakos. "Survey on routing in data centers: insights and future directions." IEEE Network 25, no. 4 (2011): 6–10. http://dx.doi.org/10.1109/mnet.2011.5958002.

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45

Potter, Tom G., and Janet E. Dyment. "Is outdoor education a discipline? Insights, gaps and future directions." Journal of Adventure Education and Outdoor Learning 16, no. 2 (2016): 146–59. http://dx.doi.org/10.1080/14729679.2015.1121767.

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46

Lim, Weng Marc. "Understanding the selfie phenomenon: current insights and future research directions." European Journal of Marketing 50, no. 9/10 (2016): 1773–88. http://dx.doi.org/10.1108/ejm-07-2015-0484.

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Purpose This paper aims to define the conceptual boundary of the selfie and to discuss the role of the selfie in the social media marketplace. Design/methodology/approach This paper extensively reviews and draws themes from the extant literature on consumer identities in the social media marketplace to explain the selfie phenomenon and to identify potentially fruitful directions for further research. Findings Current insights into the selfie phenomenon can be understood from socio-historical, technological, social media, marketing and ethical perspectives. Research limitations/implications Des

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47

Fletcher, Jonathan A. "KIT Oncogenic Mutations: Biologic Insights, Therapeutic Advances, and Future Directions." Cancer Research 76, no. 21 (2016): 6140–42. http://dx.doi.org/10.1158/0008-5472.can-16-2646.

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48

Sheikh, Javed K., Shahab S. Sohail, and Sultan Alam. "Enhancing patient education with ChatGPT: Critical insights and future directions." Indian Journal of Anaesthesia 68, no. 12 (2024): 1112–13. https://doi.org/10.4103/ija.ija_784_24.

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49

De Sanctis, Rita, Paola Tiberio, Alberto Zambelli, and Armando Santoro. "Transforming Breast Cancer Care: Cutting-Edge Insights and Future Directions." Journal of Clinical Medicine 13, no. 22 (2024): 6697. http://dx.doi.org/10.3390/jcm13226697.

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50

Tao, Hui, Kai-Hu Shi, Jing-Jing Yang, and Jun Li. "Epigenetic mechanisms in atrial fibrillation: New insights and future directions." Trends in Cardiovascular Medicine 26, no. 4 (2016): 306–18. http://dx.doi.org/10.1016/j.tcm.2015.08.006.

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