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Dissertations / Theses on the topic 'Insights'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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1

Petersson, Erik, and Oscar Östergaard. "Two Styles of the Insight Creation Process : A multiple case study of how four organizations gain insights from external information." Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-176559.

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Using external information to gain insights is becoming increasingly important in today’s knowledge based economies. However, from both research and practice it is somewhat unclear how organizations manage these activities. Therefore the purpose of this paper is to explore how four different organizations manage their insight creation process from external information. To do this, a literature review about insight creation is done to create an analytical framework. Based on this framework, the insight creation process is analyzed within the organizations to find characteristics of each process
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2

Burgess, Mary Catherine. "Insights into microbial metabolism." Thesis, Montana State University, 2012. http://etd.lib.montana.edu/etd/2012/burgess/BurgessMC0512.pdf.

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Nitrogen fixation (catalyzed by the enzyme nitrogenase), cellular respiration (completed through the Tricarboxylic Acid (TCA) cycle) and mercury detoxification (through mercury methylation) are three metabolic processes used by a wide variety of microorganisms, but that also have far reaching impacts on nutrient cycling in the environment. Roseiflexus castenholzii has been found to have a unique nitrogenase gene cluster encoding several nitrogenase homologs, including the structural proteins NifH and NifDK and the radical SAM protein, NifB, necessary for cofactor biosynthesis. However, the gen
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3

Dingwall, Paul. "Mechanistic insights into organocatalysis." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/22181.

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With a resurgence of interest at the turn of the millennium, organocatalysis has become an established field in chemical research. Proline, in particular, has played a central role in the profusion of research. As the archetypal organocatalyst, proline mediated transformations have acted as a point of reference against which the performance of new developments in the field are benchmarked and compared. The field as a whole has benefited from a timely merging of complementary experimental, kinetic, and computational studies, through which a comprehensive picture of reaction mechanisms has been
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4

Grad, Sorin Mihai. "New insights into conjugate duality." Doctoral thesis, Universitätsbibliothek Chemnitz, 2006. http://nbn-resolving.de/urn:nbn:de:swb:ch1-200601100.

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With this thesis we bring some new results and improve some existing ones in conjugate duality and some of the areas it is applied in. First we recall the way Lagrange, Fenchel and Fenchel - Lagrange dual problems to a given primal optimization problem can be obtained via perturbations and we present some connections between them. For the Fenchel - Lagrange dual problem we prove strong duality under more general conditions than known so far, while for the Fenchel duality we show that the convexity assumptions on the functions involved can be weakened without altering the conclusion. In order
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5

Berrett, Timothy. "Strategic insights into sport sponsorship." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq22951.pdf.

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6

Krebs, Nils. "New insights for femtosecond spectroscopy." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-162994.

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7

Manchanda, Rohit. "New insights into sympathetic transmission." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238131.

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8

Slutskaya, Natasha. "Carnivalesque insights in identity transformation." Thesis, University of Exeter, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502717.

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9

Gibson, Robert Patrick. "Structural insights into trehalose biosynthesis." Thesis, University of York, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423843.

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10

Smith, Mark Burnham. "Ecological insights from bacterial networks." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/93030.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2014.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 93-101).<br>Microbes occupy a wide range of important niches ranging from global biogeochemical cycles to metabolism in the human gut. Yet microbes rarely act in isolation. Instead, they thrive in complex communities with myriad combinatorial interactions. In this work I explore the nature of these bacterial networks, using computational tools to uncover ecological associations with relevance to both human health and environm
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11

Teo, Hsiang Ling. "Structural insights into ESCRT complexes." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614102.

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12

Hsieh, I.-Yun Lisa. "Insights into future electric mobility." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/127890.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, May, 2020<br>Cataloged from the official PDF of thesis.<br>Includes bibliographical references (pages 218-239).<br>Growing global awareness of the environmental impacts of combustion is accelerating electric vehicles (EVs) adoption. However, future sustainable mobility cannot be achieved without substantial changes in vehicle technology, consumer behavior, infrastructure systems, and policy. Great impacts and uncertainties are anticipated during the transition towards electric mobility. This thesis exami
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13

Andrews, Michelle. "Mobile Technologies and Consumer Insights." Diss., Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/332146.

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Business Administration/Marketing<br>Ph.D.<br>Mobile technology is changing the way consumers consume content and connect with others. At the same time, marketers admit that effectively implementing mobile targeting and promoting deals through mobile devices remains a challenge. To address these challenges and reveal consumer insights in the mobile marketing space, I propose a research stream via three essays that investigate the contextual factors that influence consumer receptivity to mobile messages. One of these factors is environmental contexts, such as the crowdedness of a consumer's env
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14

Maharjan, Rajani. "New Insights in Adrenal Tumourigenesis." Doctoral thesis, Uppsala universitet, Institutionen för kirurgiska vetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-326149.

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Unilateral cortisol producing adenoma (CPA) is the most common cause of ACTH-independent Cushing’s syndrome and is surgically curable. On the other hand, adrenocortical carcinomas (ACCs) are rare and aggressive tumours. Although the overall survival of the patients with ACC is very poor, the outcome can be heterogeneous and vary significantly between the patients. This thesis comprises studies showing genetic and genomic events occurring in CPAs and ACCs, their functional impact and clinical correlations. The Wnt/β-catenin and cAMP/PKA signalling pathways are crucial in adrenal homeostasis and
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15

Baltussen, Guido. "New insights into behavioral finance." [Amsterdam] : Rotterdam : Thela Thesis ; Erasmus University [Host], 2008. http://hdl.handle.net/1765/14104.

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16

Rong, Guoxin, Hongyun Wang, and Bjӧrn M. Reinhard. "Insights from a nanoparticle minuet." Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-184924.

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17

GAMBASSI, SILVIA. "Novel insights into alkaptonuria physiopathology." Doctoral thesis, Università di Siena, 2016. http://hdl.handle.net/11365/1004463.

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Alkaptonuria (AKU) is an ultra-rare genetic disease resulting from a deficient activity of the enzyme homogentisate 1,2- dioxygenase (HGD), responsible for the catabolism of the aromatic amino acids Phenylalanine and Tyrosine. This condition leads to the accumulation of a toxic metabolite, HGA and of its product of oxidation BQA, whose polymerization generates melanin-like aggregates, with amyloidogenic properties, leading to the phenomenon of “Ochronosis”. The most affected structures by the deposition of these ochronotic aggregates are joints, which undergo severe arthropathy; therefore, art
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18

Gill, Anila Fiaz. "Insights into Sulfonated Phthalocyanines; Insights into Anionic Tetraaryl Porphyrins; Irradiation of Cationic Metalloporphyrins Bound to DNA." unrestricted, 2006. http://etd.gsu.edu/theses/available/etd-11122006-111108/.

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Thesis (Ph. D.)--Georgia State University, 2006.<br>Title from title screen. Dabne White Dixon, committee chair; Kathryn Betty Grant, Markus W. Germann, committee members. Electronic text (252 p. : ill., charts (some col.)) : digital, PDF file. Description based on contents viewed June 18, 2007. Includes bibliographical references.
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19

Staron, Maret Avelyn, of Western Sydney Hawkesbury University, and Faculty of Social Inquiry. "A personal perspective on organisations : head, heart and soul." THESIS_FSI_SEL_Staron_M.xml, 1999. http://handle.uws.edu.au:8081/1959.7/321.

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Through a heuristics approach, the author began an exploration of the meaning, both intellectually and emotionally, of personal experiences in organisations. Change and learning was focused on, and how continual rounds of restructuring impacted on the writer as a participant/observer. The lack of spirituality in organisations, how we hide our hearts and souls and how we seek certainty using static models, theories and plans became underlying themes through the work. The findings of the research include outputs such as the development of an organisational model of complexity, but more so outcom
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20

Hernando, Herráez Irene 1985. "Evolutionary insights into human DNA methylation." Doctoral thesis, Universitat Pompeu Fabra, 2015. http://hdl.handle.net/10803/392140.

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DNA methylation is a crucial epigenetic modification involved in numerous biological processes. However, despite its functional importance, the evolutionary history of this modification and the mechanisms diving such changes are poorly understood. The aim of this thesis is to provide a better understanding of DNA methylation in the context of human recent evolution. We identified and described hundreds of regions presenting a human-specific DNA methylation pattern compared to great apes. We also analyzed for the first time the relationship between DNA methylation changes and sequence evolution
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21

Busam, Robert Durstberger. "Exonuclease I : structural and biochemical insights/." view abstract or download file of text, 2005. http://wwwlib.umi.com/cr/uoregon/fullcit?p3190508.

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Thesis (Ph. D.)--University of Oregon, 2005.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 83-89). Also available for download via the World Wide Web; free to University of Oregon users.
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22

Pongpanich, Chaipong. "Insights into product manufacturing location decisions." Thesis, University of Cambridge, 1999. https://www.repository.cam.ac.uk/handle/1810/251481.

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23

Cessford, Erin Lauren. "Mechanistic Insights into Necroptosis of Macrophages." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31771.

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Cell death is an imperative mechanism for the development, homeostasis and survival of an organism. Various forms of cell death have been documented and recent reports indicate that the mode of cell death elicited can have a profound influence on the development and perpetuation of inflammation. Apoptosis is the predominant, programmed pathway of cell death, which ensures physiological elimination of unwanted cells. On the other hand, another cell death pathway described as programmed necrosis (necroptosis), has recently been revealed. The induction of necroptosis and its impact in host bio
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24

Pisetta, Vincent. "New Insights into Decision Trees Ensembles." Thesis, Lyon 2, 2012. http://www.theses.fr/2012LYO20018/document.

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Les ensembles d’arbres constituent à l’heure actuelle l’une des méthodes d’apprentissage statistique les plus performantes. Toutefois, leurs propriétés théoriques, ainsi que leurs performances empiriques restent sujettes à de nombreuses questions. Nous proposons dans cette thèse d’apporter un nouvel éclairage à ces méthodes. Plus particulièrement, après avoir évoqué les aspects théoriques actuels (chapitre 1) de trois schémas ensemblistes principaux (Forêts aléatoires, Boosting et Discrimination Stochastique), nous proposerons une analyse tendant vers l’existence d’un point commun au bien fond
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25

Goormaghtigh, Frederic. "New insights into the persistence phenomenon." Doctoral thesis, Universite Libre de Bruxelles, 2016. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/235567.

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Together with the current antibiotic resistance crisis, bacterial persistence appears to play an increasingly important role in the frequent failure of antibiotic treatments. Persister cells are rare bacteria that transiently become drug tolerant, allowing them to survive lethal concentrations of bactericidal antibiotics. Upon antibiotic removal, persister cells are able to resume growth and give rise to a new bacterial population as sensitive to the antibiotic as the original population. Interest in persister cells seriously increased in the past few years as these phenotypic variants were sh
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26

Ferdinandusse, Sacha. "New insights in peroxisomal [beta]-oxidation." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2002. http://dare.uva.nl/document/64403.

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27

Rajan, Angelique Chettiparamb. "Complexity theory and planning : methodological insights." Thesis, Cardiff University, 2005. http://orca.cf.ac.uk/55567/.

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The main research question that the thesis addresses is 'what is the relevance of complexity theory for planning'. Having set out to examine a theoretical question, the thesis is guided by the nature of theory development. The realm of generalised discourse, theory contextualisation and empirical examination are thus addressed. The argument starts from an understanding of the nature of complexity theory as it emerges from within the natural sciences. The philosophical grounds of the theory and the way in which complexity theory might relate to the social realm are then discussed. Planning is c
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28

Birch, L. M. "Computational insights into protein-ligand interactions." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596648.

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This thesis describes the use of computational methods as a method of gaining greater insight into protein-ligand interactions, both at the molecular-recognition level and as an aid to mechanistic interpretation. Chapter Two:Part One addresses one of the major approximations in molecular docking, the rigid protein approximation. A “cross-docking” study was conducted using 31 neuraminidase complexes. It was shown that some protein conformations are more able to bind a wide variety of ligands than others but that it is possible to obtain a correct binding mode even if small conformational change
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29

Lim, Ee Tuan. "Neurodegenerative markers : insights into multiple sclerosis." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1444993/.

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Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) characterised pathologically by inflammation, demyelination and variable degrees of axonal loss and gliosis. Remyelination, axonal and synaptic plasticity have been identified as mechanisms underlying functional recovery. MS typically follows a chronic course, in the sense that new episodes or steady progression are the rule. Currently radiological surrogates of inflammation, demyelination and axonal loss are available, but these correlate only modestly with the development of cumulative disabi
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30

McManus, Edward. "Structural insights into lipoate protein ligases." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614075.

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31

Shobe, Amber R. "Insights into Perspectives on Environmental Sustainability." UKnowledge, 2015. http://uknowledge.uky.edu/cld_etds/19.

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As scientists become more aware of the imposing threats associated with climate change, university leaders are encouraged to become familiar with the principles of sustainability. Abundant research already supports the relevance of environmental sustainability in higher education; however, there exists a gap in the literature which investigates an understanding of environmental sustainability and the implementation of its practices. By examining colleges at the University of Kentucky, this study identifies organizational barriers to recognizing a thorough understanding of environmental sustain
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32

Al-Mayahy, Mohammed Hussain Neama. "Insights regarding drug permeation into skin." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/47341/.

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In order to develop safe and effective topical and transdermal formulations to treat either local skin disorders or for systemic drug delivery, it is first imperative to assess skin permeation using a reliable and comprehensive analysis method. The assessment of drug permeation into/across the skin is traditionally accomplished using Franz diffusion cells with subsequent analysis by conventional chromatographic methods such as HPLC and more recently using advanced imaging techniques. In this context, time of flight-secondary ion mass spectrometry (ToF-SIMS) offers distinctive advantages in map
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33

Atiq, Muhammad. "Sustainable corporate entrepreneurship : insights from Pakistan." Thesis, University of Southampton, 2014. https://eprints.soton.ac.uk/365500/.

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Sustainable corporate entrepreneurship (SCE) is the process of taking an opportunity-centred approach to latent and manifest social and/or environmental problems in order to create shared value, i.e. value for the business and society simultaneously. In practice, this means launching green products, conserving the use of natural resources, educating stakeholders, engaging in trust-building activities, greening of the supply chain, showing concern for employees, and producing products in response to unmet societal needs. SCE is an emerging field, which has been mostly studied in the context of
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34

Ходцева, Алла Олександрівна, Алла Александровна Ходцева, and Alla Oleksandrivna Khodtseva. "Insights into Formative Assessment in ELT." Thesis, Sumy State University, 2017. http://essuir.sumdu.edu.ua/handle/123456789/67243.

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Overall, the study reveals that, based on the students’ and the faculty members’ responses, the impact of assessment depends whether the assessment assesses (measures) what it intends to assess. Forms, environment, and the intended objectives of classroom assessment are the three main indicators of good assessment. The impact of assessment is significantly observable on students’ performance. The way students approach learning determines the way they think about classroom assignments and tests. Recent studies advocate for including students in the process of developing assessment tools
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35

Watson, Robert. "Addressing predictable irrationality: insights from practice." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29674.

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The traditional repertoire of techniques available to mediators is well-suited to assisting negotiators in resolving their disputes where those negotiators are acting in a manner approximating axiomatic rational behaviour. These techniques rely on parties acting in this manner and effectively and accurately uncovering, processing and calculating all the necessary information to make decisions in maximising their utility. Behavioural-Economists have made great progress in illustrating that human beings do not follow these axioms when making economic-decisions and have identified a number of way
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36

Bean, Rachel Christy Reid. "Trail runners: Neuromuscular and biomechanical insights." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29554.

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Running is a popular recreational and competitive sport worldwide. Despite numerous proven health benefits associated with road running, the risk of sustaining a running-related injury (RRI) is extremely high. The cause of RRI is multifactorial and the result of running many kilometres on monotonous and mechanically stiff road surfaces has been suggested to increase the risk of sustaining an injury. Interestingly, this notion may be a key driving factor for the emergence and growing interest in, trail or 'off-road’ running. Research investigating road running has been well-described, whereas t
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37

Smith, Brian A. "Mechanistic insights into a reverse polymerase." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1353507187.

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38

Waters, Catherine. "Insights into Fhit loss-induced tumorigenesis." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1438185414.

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39

Xie, Jeffrey Xinshuo. "Molecular Insights into Chronic Kidney Disease." University of Toledo Health Science Campus / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=mco1500201100900825.

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40

Zumbro, Emiko. "Computational insights into multivalently binding polymers." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/129045.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Materials Science and Engineering, 2020<br>Cataloged from student-submitted PDF of thesis.<br>Includes bibliographical references (pages 253-264).<br>Multivalent binding is commonly used throughout biology to create strong, conformal bonds using multiple weak binding interactions simultaneously. Bonds are considered multivalent when multiple ligands on one species simultaneously bind to multiple receptors on another species. Together, this bond can be much stronger than the sum of its parts. Throughout this thesis, we use the
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41

Benites, Luiz Felipe. "Genomic insights into mamiellophyceae organismal interactions." Thesis, Sorbonne université, 2019. https://tel.archives-ouvertes.fr/tel-03330155.

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Les algues Mamiellophyceae constituent la base des milieux marins côtiers. Malgré leur importance écologique, les aspects liés à leurs interactions avec l'organisme restent énigmatiques. Les "single cell genomes" (SCGs) issus d'échantillons non cultivés permettent d'identifier des associations biotiques, du sexe au parasitisme. Chez les protistes, le sexe est déterminé par les mating types (MTs), qui sont présents dans l'Ostreococcus. Ici, nous avons utilisé des données génétiques pour répondre: Comment les MTs ont-ils évolué dans ce groupe? Peut-on trouver des signaux d'inte
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42

Subissi, Lorenzo. "Biochemical insights into SARS-CoV replication." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM5002.

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Mon travail de thèse s'est focalisé sur la machinerie enzymatique impliquée dans la réplication du génome ARN du Syndrome Respiratoire Aigu Sévère-Coronavirus (SRAS-CoV). J'ai montré in vitro que l'activité ARN polymérase ARN-dépendante (RdRp) portée par nsp12 nécessite le complexe nsp7/nsp8, qui agit comme facteur de processivité. Grâce à ce complexe polymérase hautement actif, j'ai pu en suite étudier le mécanisme de "proofreading" (correction d'épreuve) associé aux coronavirus, pour lequel seulement des preuves indirectes avaient été assemblées. En effet, les coronavirus codent pour une act
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Mallawaaratchy, Duthika Marian. "Proteomic insights into gliobastoma tumour invasion." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/14731.

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Glioblastoma (GBM) is the most common, primary malignant brain tumours in adults. A better understanding of GBM biology is required to identify targets and develop new therapeutics. Tumour invasion is facilitated by cell migration and degradation of the extracellular matrix (ECM). Invadopodia are actin-rich organelles that degrade the ECM and thereby actively re-modelling the surrounding tumour microenvironment. We have characterised the invasiveness of nine established GBM cell lines using an invadopodia assay and performed quantitative MS-based proteomic analyses on enriched membrane fractio
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44

Webster, Kellie. "Improved Coreference Resolution Using Cognitive Insights." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/15468.

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Coreference resolution is the task of extracting referential expressions, or mentions, in text and clustering these by the entity or concept they refer to. The sustained research interest in the task reflects the richness of reference expression usage in natural language and the difficulty in encoding insights from linguistic and cognitive theories effectively. In this thesis, we design and implement LIMERIC, a state-of-the-art coreference resolution engine. LIMERIC naturally incorporates both non-local decoding and entity-level modelling to achieve the highly competitive benchmark perfo
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45

Martin, Laura. "Insights into the tuberculosis diagnostic pathway." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/33125.

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Background: Early identification of patients with drug-resistant tuberculosis (DR-TB) is important. Existing first and second-line drug (SLD) susceptibility testing (DST) strategies can be slow, unreliable and inaccessible. Methods and Findings: SLD DST on the MODS platform (MODS+): 97 drug-naïve and on-treatment patients provided sputum samples for analysis by MODS+ for SLDs. Agreement of MODS+ results with proportions method was >80% for fluoroquinolones and second-line injectables but suboptimal for ethambutol, pyrazinamide, streptomycin, cycloserine, ciprofloxacin and ethionamide. Perform
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Pascut, Devis. "Molecular insights for overcoming Hepatocellular Carcinoma." Doctoral thesis, Università degli studi di Trieste, 2012. http://hdl.handle.net/10077/7859.

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2010/2011<br>SUMMARY Introduction. Hepatocellular Carcinoma (HCC) ranks fifth in frequency of cancers in the world. Orthotopic Liver Transplantation (OLT) or liver resection represents the best treatments for HCC. However, most patients cannot be subjected to potential curative OLT or resection because of extensive tumor involvement of the liver, metastasis, invasion of the portal vein or advanced underlying hepatocellular disease at the time of diagnosis. Systemic chemotherapy or chemoembolization represent a good alternative for the treatment, however drug therapy of cancer in general i
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Dall'Olmo, Luigi. "New Insights In Experimental Esophageal Carcinogenesis." Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3422915.

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Gastro-esophageal reflux disease (GERD) is a relevant health problem worldwide. It impairs patients' quality of life and predisposes to intestinal-like esophageal metaplasia (i.e. Barrett's esophagus, BE), that is recognized as the major risk factor for the development of esophageal adenocarcinoma (Eac). The incidence of Eac has dramatically increased since the mid of the 1970s in the USA and Western countries for unknown reasons, while the prognosis of Eac has only slightly been improved. During the same time potent acid suppressors have been introduced for the treatment of GERD. Nowadays t
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48

CRIVELLO, PIETRO. "New molecular insights into HLA immunogenicity." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2012. http://hdl.handle.net/10281/29854.

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Alloreactivity is the major barrier to solid organ and hematopoietic stem cell transplantation (HSCT), determining important clinical events such as graft rejection and graft versus host disease. This biological phenomenon is due to the immunogenicity of allogeneic Human Leukocyte Antigens (HLA) expressed in transplanted tissues and recognized by T cell receptor (TCR) on the surface of alloreactive T cells. In the past, the hosting laboratory identified an immunogenic T cell epitope (TCE) encoded by a subset of HLA-DPB1 alleles, thereby defining permissive and non-permissive DPB1 mismatches be
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49

Torrents, Verdaguer Genís. "New insights into holography from supersymmetric localization." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/398760.

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Maldacena's conjecture, often known as the holographic duality or the AdS/CFT correspondence, proposes an equivalence between gravitational theories in a hyperbolic space of a certain dimensionality and gauge theories living on its boundary. The manner in which this connection is established makes the duality specially remarkable: both sides are thought to describe the very same string theoretic physics, but the validity regimes of the two descriptions are disjoint, and one expects either framework to be in its regime of validity the appropriate way to effectively reexpress the physics of the
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50

Salazar, Serrano Luis José. "Weak value amplification : new insights and applications." Doctoral thesis, Universitat Politècnica de Catalunya, 2016. http://hdl.handle.net/10803/404048.

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Abstract:
Weak Value Amplification (WVA) is a signal enhancement technique proposed in 1988 by Aharonov, Albert, and Vaidman that has been widely used to measure tiny changes that otherwise cannot be determined because of technical limitations. It is based on: i) the existence of a weak interaction which couples a property of a system (the system) with a separate degree of freedom (the pointer), and ii) the measurement of an anomalously large mean value of the pointer state (weak mean value), after appropriate pre and post-selection of the state of the system. The usefulness of weak value amplification
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