Academic literature on the topic 'Insilico'

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Journal articles on the topic "Insilico"

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Rick Mullin. "Exelixis gets Insilico compound." C&EN Global Enterprise 101, no. 31 (2023): 13. http://dx.doi.org/10.1021/cen-10131-buscon15.

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Kartika, Aprilia Indra. "Optimization of DCR1 and DCR2 epigenetic annealing temperatures for breast cancer biomarker using in-silico and in-vitro study." Jurnal Teknologi Laboratorium 11, no. 1 (2022): 25–32. http://dx.doi.org/10.29238/teknolabjournal.v11i1.327.

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The epigenetics of methylated and unmethylated DCR1 and DCR2 (decoy receptors 1 and 2) are genes encoding membrane receptors that can bind to TRAIL causing TRAIL inhibition in the apoptotic pathway. Epigenetic detection of DCR1 and DCR2 was developed as a biomarker of breast cancer. One of the detection methods is using PCR. The most important step in the PCR process is the determination of the annealing temperature. This research performs Tm analysis using the insilico program from Neb, insilico, Thermofisher, and Promega and in vitro optimization. Methylated DCR1 can be amplified at annealin
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Christopher Busayo Olowosoke, Adebola Abosede Alaba, and Benjamin Babatunde Adegboyega. "Citrullus lanatus natural product library: A hoard of viable potential inhibitor candidates for diabetes mellitus type II therapeutic target enzymes." World Journal of Advanced Research and Reviews 15, no. 1 (2022): 534–60. http://dx.doi.org/10.30574/wjarr.2022.15.1.0713.

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The ethnomedicinal function of several cucurbit species (cucumber, squash, melon, gourd, etc.) on diseases (i.e. diabetes, microbial infections, cancer, etc.), and as free radical scavengers have been reported. However, there remains infinitesimal record on citron watermelon broad use, which reflects the reason for wide oversight of underutilization, from lack of recognition for functional food crop development and commercialization. The objective of this study focus towards identifying the natural phytochemicals of C. lanatus on water melon molecules online database for insilico computational
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Christopher, Busayo Olowosoke, Abosede Alaba Adebola, and Babatunde Adegboyega Benjamin. "Citrullus lanatus natural product library: A hoard of viable potential inhibitor candidates for diabetes mellitus type II therapeutic target enzymes." World Journal of Advanced Research and Reviews 15, no. 1 (2022): 534–60. https://doi.org/10.5281/zenodo.7745429.

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The ethnomedicinal function of several cucurbit species (cucumber, squash, melon, gourd, etc.) on diseases (i.e. diabetes, microbial infections, cancer, etc.), and as free radical scavengers have been reported. However, there remains infinitesimal record on citron watermelon broad use, which reflects the reason for wide oversight of underutilization, from lack of recognition for functional food crop development and commercialization. The objective of this study focus towards identifying the natural phytochemicals of&nbsp;<em>C. lanatus</em>&nbsp;on water melon molecules online database for ins
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Shambharkar, Saroj, K. Vaishali, Rachna Somkunwar, Yogeshri Choudhari, and Jyotsna Gawai. "Biological Network, Gene Regulatory Network Inference Using Causal Inference Approach." Revue d'Intelligence Artificielle 36, no. 1 (2022): 139–45. http://dx.doi.org/10.18280/ria.360116.

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In system biology inference from gene regulatory network (GRN) is a challenging task. There exist different computational techniques to analyze the causal relationships between the pair of genes and to understand the significance of causal relationship in gene regulatory network. The DREAM4 insilico network structure and insilico gene expression time series dataset of DREAM challenge dataset is examined. This gene expression dataset of insilico of size 10 is analyzed for inferring causal relationships of the GRN inference. The analysis of dataset showing the gene expression data values are var
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Bloom, Mark. "Biology insilico: The Bioinformatics Revolution." American Biology Teacher 63, no. 6 (2001): 400–407. http://dx.doi.org/10.1662/0002-7685(2001)063[0397:bistbr]2.0.co;2.

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Selvaraj, Jubie, Shyam Sundar P, Logesh Rajan, et al. "Identification of (2R,3R)-2-(3,4-dihydroxyphenyl)chroman-3-yl-3,4,5-trihydroxy benzoate as multiple inhibitors of SARS-CoV-2 targets; a systematic molecular modelling approach." RSC Advances 11, no. 22 (2021): 13051–60. http://dx.doi.org/10.1039/d1ra01603b.

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Krishna, P. Navya, and Y. Mukesh Mohite. "Insilico Activity Prediction of Thiazolidinediones Derivatives." Asian Journal of Pharmaceutical Analysis 8, no. 1 (2018): 39. http://dx.doi.org/10.5958/2231-5675.2018.00007.8.

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Tripathy, Mr Chandra Sekhar, Dr Anil Kumar, Dr Santosh Kumar Behera, et al. "DengueVrsEllagic Acid & Ferric Carboxymaltose: InSilico." Saudi Journal of Biomedical Research 7, no. 7 (2022): 211–18. http://dx.doi.org/10.36348/sjbr.2022.v07i07.001.

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Backgrounds: Dengue viruses are transmitted to humans via mosquito bites from infected Aedes species (Aedesaegypti or Aedesalbopictus). Dengue fever affects over half of the world's population, or about 4 billion people. Dengue fever is a common cause of sickness in high-risk settings. Methods: In the current study two serotypes of Dengue viruses namely DENV1 and DENV2 taken for the study. Here two important compounds namely Ellagic acid and Ferric Carboxymaltose chosen for the targets to be inhibited. In silico docking approach performed to dock the two compounds against the DENV1 and DENV2 v
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R.A., Ranganadha. "Insilico studies of tau-protein kinase." Advances in Modelling and Analysis B 61, no. 4 (2018): 211–14. http://dx.doi.org/10.18280/ama_b.610406.

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Dissertations / Theses on the topic "Insilico"

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Sharma, Anurag. "An Insilico Design of Nanoclay Based Nanocomposites and Scaffolds In Bone Tissue Engineering." Diss., North Dakota State University, 2016. http://hdl.handle.net/10365/25907.

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A multiscale in silico approach to design polymer nanocomposites and scaffolds for bone tissue engineering applications is described in this study. This study focuses on the role of biomaterials design and selection, structural integrity and mechanical properties evolution during degradation and tissue regeneration in the successful design of polymer nanocomposite scaffolds. Polymer nanocomposite scaffolds are synthesized using aminoacid modified montmorillonite nanoclay with biomineralized hydroxyapatite and polycaprolactone (PCL/in situ HAPclay). Representative molecular models of polymer na
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Buhry, Laure. "Estimation de paramètres de modèles de neurones biologiques sur une plate-forme de SNN (Spiking Neural Network) implantés "insilico"." Thesis, Bordeaux 1, 2010. http://www.theses.fr/2010BOR14057/document.

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Ces travaux de thèse, réalisés dans une équipe concevant des circuits analogiques neuromimétiques suivant le modèle d’Hodgkin-Huxley, concernent la modélisation de neurones biologiques, plus précisément, l’estimation des paramètres de modèles de neurones. Une première partie de ce manuscrit s’attache à faire le lien entre la modélisation neuronale et l’optimisation. L’accent est mis sur le modèle d’Hodgkin- Huxley pour lequel il existait déjà une méthode d’extraction des paramètres associée à une technique de mesures électrophysiologiques (le voltage-clamp) mais dont les approximations success
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Dade, Sébastien. "Identification insilico et validation expérimentale de gènes spécifiquement exprimés dans l'ovocyte de mammifères : les MATER-like et les oogénésines." Tours, 2006. http://www.theses.fr/2006TOUR4002.

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Grâce à l'augmentation exponentielle des séquences disponibles dans les banques de données d'une part et le développement de logiciels permettant leur analyse d'autre part, nous avons généré in silico une liste de gènes candidats potentiellement spécifiques de l'ovocyte. Ceci a pu se faire grâce à l'utilisation d'un outil de soustraction de banques d'EST depuis le site du NCBI (http:/www. Ncbi. Nlm. Nih. Gov/), le Digital Differential Display (DDD). Ces gènes candidats ont fait l'objet l'études expérimentales pour un certain nombre d'entre eux, notamment des gènes simulaires à NALP5/MATER et d
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Kolluri, Satya Krishna Prasanna. "Evaluation of performance of MSI detection tools using targeted sequencing data." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-453793.

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In recent years, digitalization and computer-based technologies have greatly revolutionized the field of bioinformatics. Advance research and development of computer-based programs have enhanced various DNA sequencing technologies. This advancement has significantly broadened our understanding of genomic evolution and has widely contributed to the application of clinical genomics. Cancer has been one of the major causes of death across the world. Cancer is mainly caused due to the damage or changes in DNA that affect the function of genes which contain a set of instructions that control variou
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BATISTA, Lucr?cia de Mascarenhas. "Vozes do insilio: o Movimiento Cristiano de Liberaci?n entre dissid?ncia e oposi??o em Cuba (1988-2002)." Universidade Federal Rural do Rio de Janeiro, 2013. https://tede.ufrrj.br/jspui/handle/jspui/2262.

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Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2018-04-27T17:54:24Z No. of bitstreams: 1 2013 - Lucr?cia de Mascarenhas Batista.pdf: 512428 bytes, checksum: 2e16fcd0fec935501ab5399e313e6468 (MD5)<br>Made available in DSpace on 2018-04-27T17:54:24Z (GMT). No. of bitstreams: 1 2013 - Lucr?cia de Mascarenhas Batista.pdf: 512428 bytes, checksum: 2e16fcd0fec935501ab5399e313e6468 (MD5) Previous issue date: 2013-02-22<br>CAPES<br>This work intents to discuss the relationship between the left-wing sets and the opposition regarding the historical experience of h ?Movimiento Cristiano de Libe
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Capellari, Alberto. "Analisi lineare e non lineare di silos spiralati in acciaio per il contenimento di materiali sciolti." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amslaurea.unibo.it/1501/.

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RIGGIO, VINCENZO ANDREA. "Valutazione di produzione di biogas da prove sperimentali di digestione anaerobica da differenti mix di scarti da biomassa agricola." Doctoral thesis, Politecnico di Torino, 2010. http://hdl.handle.net/11583/2500106.

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Nella sperimentazione si sono valutati alcuni aspetti tecnici e tecnologici relativi alla produzione di energia, in forma di biogas, ottenuta dalla digestione anaerobica di scarti provenienti principalmente da produzioni agricole – zootecniche. Questa tecnica è ben nota e utilizzata da diversi anni, ma a fronte di un crescente interesse da parte delle autorità locali, contrappone una certa stazionarietà nella risoluzione dei principali problemi che la accompagnano. Agendo su un territorio locale che fa dell’agricoltura, e della zootecnia, uno dei comparti produttivi maggiormente soggetto a ris
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Nayak, Santosh Kumar, and Kiran Soy Murum. "Insilico Annotation of Un-characterized proteins of Mycobacterium Tuberculosis." Thesis, 2011. http://ethesis.nitrkl.ac.in/2372/1/107bt009.pdf.

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Mycobacterium tuberculosis (MTB) is a pathogenic bacteria species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. The genome of the H37Rv strain was published in 1998. Its size is 4 million base pairs, with 3959 genes; 40% of these genes have had their function characterised, with possible function postulated for another 44%. Within the genome are also 6 pseudo genes. The genome contains 250 genes involved in fatty acid metabolism, with 39 of these involved in the polyketide metabolism generating the waxy coat. Such large numbers of conserved genes show the ev
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Tewari, Aparna. "Insilico design and evaluation of hybrid Hsp 90 inhibitors for cancer therapy." Thesis, 2014. http://ethesis.nitrkl.ac.in/6413/1/E-89.pdf.

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Breast Cancer has become the second most common threat to the people all over the world. Inhibiting Hsp90 has been considered to be an excellent therapeutic approach in breast cancer where the diseased proteins are directed towards proteasomal degradation pathway. However apart from the inhibitors strong binding to Hsp90, they leave other kinds of disadvantages like solubility, and toxicity problems. In our present investigation, we have developed number of hybrid inhibitor molecules using existing Hsp90-inhibitors to achieve a higher binding potential as well as minimal toxic properties. Thus
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Singh, Ajeet. "Identification of Drug Target Against Bacteroides Fragilis 638R: Through Insilico Genome Analysis." Thesis, 2015. http://ethesis.nitrkl.ac.in/7910/1/627.pdf.

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Bacteroides fragilis is a Gram-negative, rod shaped bacterium and the most standard anaerobic bacterium creating bacteremia in people. It is a part of the normal endogenous flora in human body and is normally commensal, but can cause infection if displaced into the bloodstream or surrounding tissue following trauma, surgery or disease. In this approach we have found certain target protein which can give rise to novel drug for the B.fragilis disease 638R. All the metabolic pathways which are present in the pathogen but not present in the human are taken as unique metabolic pathways. Here there
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Books on the topic "Insilico"

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Ghosh, Arabinda. Insilico analysis of xylanases from thermophilic bacteria. LAP LAMBERT Academic Publishing, 2017.

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Calzadilla, Carelsy Falcón. Cartas desde el insilio: La construcción de la herejía desde la subalternidad. Editorial El Mar y la Montaña, 2015.

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Marín, Laura Lozano. "Era mucha indiferencia, y eso dolía": Las poetas del insilio desde la Transición. Editorial Comares, 2021.

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Priya, M. Saravana. Anatomy Biological Activity and Insilico Analysis. Quadry, Fatima, 2023.

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Gupta, Sikha. Insilico Screning & Drug Designing For Lipoic Acid-B Protein. LAP Lambert Academic Publishing, 2012.

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García, Sonia. Insilio. Editorial de la Universidad Nacional de La Plata (EDULP), 2016. http://dx.doi.org/10.35537/10915/167769.

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Una caja con cenizas. Ahí adentro hay una madre. Un libro con hojas. Acá adentro habita la historia de una hija que trata de buscar el certificado que ratifique algo tan difícil de medir como el amor. O quizás todo sea más sencillo, salvo que siempre, los sentimientos se cuentan con palabras. Sonia García suelta palabras, “palabras como nudos atadas a la altura de la panza”, palabras grandes, procaces, palabras sin palabras, palabras fuertes, palabras asociadas al mar, palabras inventadas. Así nace el término insilio. Un viaje interno, al interior de nuestros propios infiernos, al interior de
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Zamora, Hernán. Orfeado Insilio. Independently Published, 2019.

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Andarcia, Alexis. Insilio: Carta a Karim. Independently Published, 2020.

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Insilio : la Cárcel Del Silencio: Invisibilidad Lesbiana y Resistencia. Westphalia Press, 2023.

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Ltd, ICON Group. INSILICON CORP.: International Competitive Benchmarks and Financial Gap Analysis (Financial Performance Series). 2nd ed. Icon Group International, Inc., 2000.

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Book chapters on the topic "Insilico"

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Maji, Pradipta, and Sushmita Paul. "Rough Sets for Insilico Identification of Differentially Expressed miRNAs." In Scalable Pattern Recognition Algorithms. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-05630-2_7.

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Roja, Rathna, Shanker Kalakotla, Arun Reddy Ravula, et al. "Insilico Screening of Pentacyclic Triterpenoids against Vascular Dementia Target’s." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-31978-5_23.

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Dhananjaya, Gaviappa, Sylvia Mathew, and R. Deveswaran. "Insilico Analysis of Compounds Isolated from Mulberry Plant Source for Anti Cariogenicity." In Advances in Materials Science and Technology. CRC Press, 2025. https://doi.org/10.1201/9781003664277-14.

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Sharma, Anjali, Deeksha Pandey, and Navneeta Bharadvaja. "Exploring potential of Bacopa monnieri's against B19V induced erythema infectiosum: An insilico approach." In Intelligent Computing and Communication Techniques. CRC Press, 2025. https://doi.org/10.1201/9781003530176-54.

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Dhanalakshmi, G., Preenon Bagchi, and M. Anuradha. "Insilico Study of Phytochemical Component of Angelica Sinensis with Genes of Polycystic Ovarian Syndrome." In Advances in Intelligent Systems Research. Atlantis Press International BV, 2023. http://dx.doi.org/10.2991/978-94-6463-294-1_17.

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Tejaswini, Avulapati, Kusampudi Preethi Alekhya, Panjugula Manisha, Patnam Nageswari, and Konda Swathi. "Screening of Phyllanthus niruri Plant Active Constituents for Anticancer and Antifungal Activity by Insilico Methods." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-31978-5_10.

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Boye, Niels. "On Clinical, Philosophical, Ethical and Behavioural Concepts for Personalised Insilico Medicine Supporting “Co-production of Health”." In Universal Access in Human-Computer Interaction. Aging and Assistive Environments. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-07446-7_21.

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Nallagouni, C. S. Reddy, and K. Pratap Reddy. "Insilico Binding Studies of Resveratrol for Protective Effects in Neurodegeneration Using Glutamate Receptor 3B as Target Model." In Cognitive Science and Health Bioinformatics. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-6653-5_8.

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Nomura, Taishin, and Yoshiyuki Asai. "Key Concepts of insilicoML." In Harnessing Biological Complexity. Springer Japan, 2011. http://dx.doi.org/10.1007/978-4-431-53880-6_5.

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Panigrahi, Sunitha, Syed Rizwan Hasan Razvi, and Syeda Rabia Mariyam. "Insilico Characterization of the Mutational Hotspot Regions of the Enzyme Protease and an Insight to the Effect of These Mutations on the Stability of the Protein." In Next Generation DNA Led Technologies. Springer Singapore, 2015. http://dx.doi.org/10.1007/978-981-287-670-6_14.

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Conference papers on the topic "Insilico"

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Olotu, Titilayo M., Salma Gumi Ahmad, Frank Abimbola Ogundolie, and Aasia Muhammed Jamiu. "Insilico Prediction of Antibiotics resistance in Staphylococcus aureus from whole-genome sequence of selected African Countries." In 2024 International Conference on Science, Engineering and Business for Driving Sustainable Development Goals (SEB4SDG). IEEE, 2024. http://dx.doi.org/10.1109/seb4sdg60871.2024.10630041.

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Hajighasemi, F., and A. Shirkavand. "Insilico study of COVID-19 ORF1ab protein allergenicity." In ERS International Congress 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/13993003.congress-2022.3367.

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J., Alex Mathew, and Nixon Raj N. "Insilico Docking Studies on Anticancer Drugs for Breast Cancer." In 2009 International Association of Computer Science and Information Technology - Spring Conference. IEEE, 2009. http://dx.doi.org/10.1109/iacsit-sc.2009.12.

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Nicholas, Joshua, Kosalishkwaran Ganeson, Parasuraman Subramaniam, and C. Deisy. "Insilico L3-L4 Stress Prediction Using Artificial Intelligence Techniques." In 2018 IEEE 4th International Symposium in Robotics and Manufacturing Automation (ROMA). IEEE, 2018. http://dx.doi.org/10.1109/roma46407.2018.8986718.

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Priya, Ponnuraj Kirthi, and Srinivasan Jayaraman. "Hydroxychloroquine's Influence on Hypoxic and Hypokalemic ventricle: An Insilico Perspective." In 2021 Computing in Cardiology (CinC). IEEE, 2021. http://dx.doi.org/10.23919/cinc53138.2021.9662782.

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Damayanti, Dini Sri, and Annisa Iktiarani. "Chorogenic Acid, Dehydrocarpaine I and D1 Alpha Tocopherol from Papaya Leaves (Papaya Carica) as an Anti-Inflammatory Candidate That Inhibits TNF Alpha Receptors." In 7th International Students Science Congress. Izmir International guest Students Association, 2023. http://dx.doi.org/10.52460/issc.2023.049.

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Introduction. TNF alpha is a significant mediator that plays a role in acute and chronic inflammatory processes or chronic that induces cell apoptosis. Papaya leaves have anti-inflammatory effects, but the mechanism is not yet known with certainty. The study aimed to predict the mechanism of action of active compounds of papaya leaves as anti-inflammatory through the mechanism of death receptor (1DOG) / TNF receptors family inhibiting in insilico method. In addition, the study aims to determine the solubility, pharmacokinetics, and toxicity of active compounds insilico. Methods. Computational
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Rotake, Dinesh, Arpita Parakh, Shiv Govind Singh, and Jitendra B. Zalke. "Diagnostic Probes Designed for Detection of Mycobacterium Tuberculosis - An Insilico Approach." In 2023 3rd International Conference on Innovative Sustainable Computational Technologies (CISCT). IEEE, 2023. http://dx.doi.org/10.1109/cisct57197.2023.10351239.

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Abuelanin, Mohamed, Mohamed Fares, and Mohamed El-Hadidi. "Insilico Codon Bias Correction for Transgenic Biological Protein Sequences for Vaccine Production." In 2020 2nd Novel Intelligent and Leading Emerging Sciences Conference (NILES). IEEE, 2020. http://dx.doi.org/10.1109/niles50944.2020.9257881.

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Anbazhakan, K., R. Praveena, and K. Sadasivam. "Prediction of biological activities of phytoestrogen and its derivative – A Insilico study." In ADVANCES IN BASIC SCIENCE (ICABS 2019). AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5122635.

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Dhanushya, R., N. T. Devika, and B. M. Jaffar Ali. "Insilico reaction kinetic model of shear stress induced eNOS activation in arterial endothelium." In 2009 World Congress on Nature & Biologically Inspired Computing (NaBIC). IEEE, 2009. http://dx.doi.org/10.1109/nabic.2009.5393626.

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