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Dissertations / Theses on the topic 'Instability'

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1

Trouvé, Arnaud. "Instabilités hydrodynamiques et instabilités de combustion de flammes turbulentes prémélangées." Châtenay-Malabry, Ecole centrale de Paris, 1989. http://www.theses.fr/1989ECAP0097.

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Etude des modes de combustion instable observes sur une maquette de statoréacteur ou l'instabilité est le résultat d'interactions complexes entre la dynamique de l'écoulement dans la zone de réaction, les processus de dégagement de chaleur et le comportement acoustique du système confine. Etude des modes hydrodynamiques au cours d'un régime de combustion stable
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2

Gryfe, Robert. "Colorectal cancer microsatellite instability." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ59033.pdf.

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3

Strefford, Jon C. "P53 and chromosome instability." Thesis, Swansea University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639125.

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This research project utilised methodologies from the fields of genetic toxicology and cytogenetic to accurately assess chromosome damage in p53-modified cell lines. Three primary diploid fibroblast cell lines were used; a control cell exhibited wild-type p53 characteristics, a mutant p53 cell line with a codon 143<SUP>val-ala</SUP> mutation, and a near null cell line containing transcripts for the E6 onco-fragments from the human papillomavirus type 16. These cell lines were characterised cytogenetically, and treated with genotoxic compounds so that the degree of chromosome damage could be as
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4

Foreman, S. J. "Baroclinic instability and blocking." Thesis, University of Reading, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354071.

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5

Wood, R. A. "Instability of oceanic fronts." Thesis, University of Exeter, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381309.

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6

Williamson, David. "Haemoglobin mutation and instability." Thesis, Open University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315297.

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7

Jomah, Adel M. "Instability in switching systems." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322593.

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8

BUFFONI, SALETE SOUZA DE OLIVEIRA. "PARAMETRIC INSTABILITY OF COLUMNS." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 1998. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=2132@1.

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COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR<br>UNIVERSIDADE FEDERAL DO PARÁ<br>O presente trabalho tem por objetivo desenvolver uma formulação e certas estratégias que permitam a análise da perda de estabilidade de colunas esbeltas submetidas a carregamento axial periódico, fenômeno este conhecido como ressonância paramétrica. Uma excitação é dita paramétrica quando aparece nas equações de movimento do sistema na forma de coeficientes variáveis com o tempo - geralmente periódicos - e não como uma não homogeneidade. A coluna é descrita pela formulação clássica de Navier.
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9

Hou, Hang-sheng. "Cavitation instability in solids." Thesis, Massachusetts Institute of Technology, 1990. http://hdl.handle.net/1721.1/13697.

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10

Miller, Ronald Lindsay. "Topics in shear instability." Thesis, Massachusetts Institute of Technology, 1990. http://hdl.handle.net/1721.1/54962.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric, and Planetary Sciences, 1990.<br>Includes bibliographical references.<br>by Ronald Lindsay Miller.<br>Viscous destabilization of stratified shear flow -- Organization of rainfall by an unstable jet aloft.<br>Ph.D.
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11

Andreoni, Federica. "SSB and genetic instability." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/3993.

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Genome stability has great importance in maintaining cell viability and optimal functionality of cellular processes. Loss of genome stability can lead to cell death in the simplest organisms and to deregulation of the cell proliferation machinery in higher organisms, potentially causing cancer or morbid states. The Single Stranded DNA Binding (SSB) protein of Escherichia coli is an essential protein that binds and stabilises ssDNA stretches. Its role is particularly crucial during DNA replication, recombination and repair processes and it has therefore been predicted to play a prominent role i
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12

Lai, Chi-hsuan. "Neutrino electron plasma instability /." Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.

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13

Pieri, Alexandre. "Turbulence barocline : effets couplés de rotation, stratification et cisaillement." Phd thesis, Ecole Centrale de Lyon, 2012. http://tel.archives-ouvertes.fr/tel-00781602.

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La finalité de cette thèse est de fournir une meilleure compréhension de la turbulence homogène anisotrope soumise à un forçage barocline. À cette fin, nous utilisons une approche numérique pseudo-spectrale basée sur la transformation de Rogallo. L'utilisation d'un tel algorithme nous permet de considérer une asymétrie des fonctions de probabilité en faveur des évènements négatifs est observée. Le lien entre la distribution de vorticité potentielle et celle d'un scalaire passif est également étudié. Il est montré qu'à faible nombre de Richardson, c'est le mode vortex (à vorticité potentielle n
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14

Wang, Chen. "Novel software tool for microsatellite instability classification and landscape of microsatellite instability in osteosarcoma." Miami University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=miami1554829925088174.

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15

Schaefer, Rodrigo Gonçalves. "Global instability in Hamiltonian systems." Doctoral thesis, Universitat Politècnica de Catalunya, 2018. http://hdl.handle.net/10803/620741.

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In Chapters 1 and 2 of this thesis, we prove that for any non-trivial perturbation depending on any two independent harmonics of a pendulum and a rotor there is global instability. The proof is based on the geometrical method and relies on the concrete computation of several scattering maps. A complete description of the different kinds of scattering maps takes place. We separate the proof of the general system in two cases. The first one is studied in Chapter 1. There, a proof is given for the simplest perturbation function. Besides, we find out some very special diffusion orbits, called "hi
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16

Kreider, Rose M. "Interracial marriage and marital instability." Click to view the dissertation via Digital dissertation consortium, 1999.

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17

Ross, Julius. "Instability of polarised algebraic varieties." Thesis, Imperial College London, 2006. http://hdl.handle.net/10044/1/1250.

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By analogy with the definition for sheaves, we define the slope of a polarised algebraic variety and of each of its subschemes. This gives a notion of slope stability, which we show is a necessary condition for K-stability. We also give the modifications needed to get a necessary condition for asymptotic Chow stability. We then give various calculations of slope and concrete examples. These examples have been chosen to be of interest to the conjectured correspondence between K-stability and the existence of K¨ahler metrics of constant scalar curvature. In particular we get new examples of pola
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18

Kim, Han Soo. "Aerodynamic instability of inclined cables." Thesis, University of Ottawa (Canada), 2001. http://hdl.handle.net/10393/8976.

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A series of wind tunnel tests was conducted to investigate the existence of the galloping instability of inclined dry cables and also to identify the influence of some parameters on it. These parameters are the structural damping and cable surface roughness, which may have significant impact on the vibration characteristics. The test results showed both the divergent type of galloping instability and the limited amplitude high wind speed vortex shedding excitation. Galloping instability was observed in only one case. Parametric study shows that the vortex shedding oscillation can be easily sup
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19

Murray, John. "Instability in the human genome." Thesis, University of Leicester, 1998. http://hdl.handle.net/2381/30309.

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The DNA flanking hypervariable minisatellite MS32 was sequenced and searched for polymorphisms. The polymorphisms found were used in recombination analysis by A.J. Jefferys which described the recombination hotspot immediately flanking MS32, and responsible for the polarity of mutation observed within the repeat array. It became apparent that gene conversion and crossover processes at the locus were probably initiated in the same manner. Comparative analysis of the sequence flanking MS32, MS31 and CEB1 revealed all were situated in an environment rich in dispersed repeats and other repetitive
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20

Coleman, Mark Giles. "Genomic instability in colorectal carcinoma." Thesis, University of Leicester, 2001. http://hdl.handle.net/2381/29371.

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Microsatellite instability (MSI) in colorectal tumours is demonstrated by PCR amplification of several different microsatellite loci. Minisatellites, which are repeats of longer sequences also found throughout the genome, may also be affected by tumorigenesis. Certain minisatellite alleles contain 2 types of similar repeat unit that are randomly interspersed. The interspersion pattern can be analysed by mapping variant repeat units along an amplified allele, minisatellite variant repeat unit mapping PCR (MVR-PCR). We have applied microsatellite analysis with ten markers and MVR-PCR for locus D
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21

Salmeron, Raquel. "Magnetorotational Instability in Protostellar Discs." Physics, 2005. http://hdl.handle.net/2123/919.

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Doctor of Philosophy<br>We investigate the linear growth and vertical structure of the magnetorotational instability (MRI) in weakly ionised, stratified accretion discs. The magnetic field is initially vertical and perturbations have vertical wavevectors only. Solutions are obtained at representative radial locations from the central protostar for different choices of the initial magnetic field strength, sources of ionisation, disc structure and configuration of the conductivity tensor. The MRI is active over a wide range of magnetic field strengths and fluid conditions in low conductivity dis
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22

Rebentisch, Eric. "Preliminary Observations on Program Instability." Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/7331.

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This white paper reports emerging findings at the end of Phase I of the Lean Aircraft Initiative in the Policy focus group area. Specifically, it provides details about research on program instability. Its objective is to discuss high-level findings detailing: 1) the relative contribution of different factors to a program’s overall instability; 2) the cost impact of program instability on acquisition programs; and 3) some strategies recommended by program managers for overcoming and/or mitigating the negative effects of program instability on their programs. Because this report comes as this r
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23

Valkhoff, Nienke Jeltje Marjoke. "Stabilization by competing instability mechanisms." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2006. http://dare.uva.nl/document/37776.

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24

Brown, Cathleen N. Guskiewicz Kevin M. "Factors contributing to ankle instability." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,272.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2006.<br>Title from electronic title page (viewed Oct. 10, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Interdisciplinary Human Movement Science (School of Medicine)." Discipline: Human Movement Science; Department/School: Medicine.
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25

Spotton, Brenda L. (Brenda Lynn). "A study of financial instability." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=41138.

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This study is a theoretical and historical study of the combined issues of destabilizing speculation and financial crises. First, we critically examine the orthodox mathematical theory of a speculative bubble. This model, we determine, is inadequate for the empirical purposes of identifying and fully explaining a bubble. Next, we examine the 19th-century British Classical view of the mania-crisis phenomenon and compare it with some of the leading early 20th-century views. We find that the 20th-century writers maintained a distinctly Classical view of the issues and that this view is fundamenta
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26

Mitmaker, Elliot. "Microsatellite instability in thyroid neoplasia." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=101730.

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Micro satellite instability (MSI) is a form of genomic instability that has recently been implicated in the pathogenesis of thyroid cancer. The purpose of this study is to further define the distribution of microsatellite instability in both normal and neoplastic thyroid follicular epithelium.<br>Using laser capture microdissection, cells from both normal and tumor tissue were individually collected. PCR amplification of the DNA was then performed using six dinucleotide and two mononucleotide microsatellite markers.<br>Forty benign and malignant thyroid tumors were compared with their adjacent
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27

Gregory, Michael Peter Robert. "Farm income inequality and instability." Thesis, Imperial College London, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338982.

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28

Kandil, Mohamed Abdelhadi. "On rotor internal damping instability." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421790.

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29

Sethia, Krishna Kumar. "The pathophysiology of detrusor instability." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235958.

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30

Erwin, Patrick Seumas. "Palaeomagnetic investigations of volcano instability." Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249474.

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31

Bhattacharya, S. "Pile instability during earthquake liquefaction." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596628.

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A theory of pile failure, based on buckling instability is proposed in this thesis. The main postulate of this theory is that if piles are too slender they require lateral support from the surrounding soil if they are to avoid buckling instability. During earthquake-induced liquefaction, the soil surrounding the pile loses effective confining stress and can no longer offer sufficient support to the pile. A slender pile may then buckle sideways in the direction of least elastic bending stiffness pushing aside the initially liquefied soil, and eventually rupturing under the increased bending mom
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32

Nguyen, Giang Huong. "Cancer, aging and genome instability." Thesis, University of Oxford, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600238.

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Bloom syndrome is a rare autosomal recessive disease caused by loss of function mutations in the BLM gene and characterized by telangiectatic erythema, proportionaJ dwarfism, immune deficiency, infertility, type II diabetes, and a predisposition to many types of cancer. It is unclear how germline mutations in BLM that encodes a helicase protein lead to the highly tissueMspecific changes and disease states associated with BS. In addition, previous works have demonstrated the various roles of BLM in DNA replication and repairs; however, there is currently no mechanism to acutely disable BLM func
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33

Gore, Whitney L. "AFFECTIVE INSTABILITY ACROSS DIAGNOSTIC MODELS." UKnowledge, 2015. http://uknowledge.uky.edu/psychology_etds/76.

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The National Institute of Mental Health’s (NIMH) Research Domain Criteria (RDoC; Insel et al., 2010; Sanislow et al., 2010) were established in an effort to explore underlying dimensions that cut across many existing disorders as well as to provide an alternative to the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (DSM-5; APA, 2013). The present dissertation aimed to study one major component of the RDoC model, negative valence, as compared to other models hypothesized to be closely related, as well as its relationship to a key component of psychopat
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Dixon, Richard Stuart. "Diagnostic studies of symmetric instability." Thesis, University of Reading, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270255.

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35

Elliott, Simon S. "Numerical studies of baroclinic instability." Thesis, University of Oxford, 1995. http://ora.ox.ac.uk/objects/uuid:eb0c26fe-b0f0-4f2b-aa3b-00428cdd2a57.

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This thesis describes two studies of baroclinic instability in a rotating fluid annulus subject to differential heating. The first part is concerned with the development of a time dependent axisymmetric numerical model. The model was formulated using the control volume finite element method and was designed to be as flexible as possible both in terms of the range of problems to be studied and the techniques used to study them. Details of these techniques are presented together with a discussion of their limitations and possible refinements and extensions which could be made. The second part of
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36

Grimshaw, P. N. "Quantitative assessment of knee instability." Thesis, University of Salford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234593.

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37

Lucey, Anthony Denis. "Hydroelastic instability of flexible surfaces." Thesis, University of Exeter, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235966.

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38

Khumbah, Fidelis Morfaw. "Instability of three-dimensional frameworks." Thesis, University of Southampton, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315305.

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39

Gajo, Alessandro. "Instability phenomena in sand samples." Thesis, University of Bristol, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399938.

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40

Andriotis, Andreas. "Fracture instability in nuclear graphite." Thesis, University of Bristol, 2018. http://hdl.handle.net/1983/8f4c72b9-6a8a-4c69-8ded-5425f847a148.

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This dissertation considers the fracture instability of nuclear graphite, specifically of isotropic Gilsocarbon, grade IM1-24, which acts as a structural component and neutron moderator within reactors. The presence of cracks within this graphite informs its behaviour and necessitates a study of fracture properties and instability. Amongst the factors studied, a major finding was that the size effect was the most prevalent. Two aspects of instability were also examined: the crack driving force or energy release rate and the fracture resistance or the incremental work of fracture. The condition
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41

Wu, Xuesong. "Nonlinear instability of Stokes-layers." Thesis, Imperial College London, 1992. http://hdl.handle.net/10044/1/59202.

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The Stokes-layer generated by a sinusoidally oscillating flat plate in an infinite fluid is an important prototype of unsteady flows, and is known to be susceptible to high-frequency instability. According to linear theory (Tromans, 1977; Cowley, 1987), small disturbances can grow exponentially over part of a period and become neutral at some time. The present study considers nonlinear effects on the instability under a high-Reynolds-number assumption, i.e. R ^ 1. It is shown that in the vicinity of the neutral time, the small disturbances evolve from a linear stage to a nonlinear stage due to
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42

Dodgson, Emily. "Thermoconvective instability in porous media." Thesis, University of Bath, 2011. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547618.

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This thesis investigates three problems relating to thermoconvective stability in porous media. These are (i) the stability of an inclined boundary layer flow to vortex type instability, (ii) front propagation in the Darcy-B´enard problem and (iii) the onset of Prantdl-Darcy convection in a horizontal porous layer subject to a horizontal pressure gradient. The nonlinear, elliptic governing equations for the inclined boundary layer flow are discretised using finite differences and solved using an implicit, MultiGrid Full Approximation Scheme. In addition to the basic steady state three configur
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43

Akl, Sherif Adel. "Wellbore instability mechanisms in clays." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/64569.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, February 2011.<br>"February 2011." Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 331-341).<br>This dissertation investigates the stability of wellbores drilled in Ko-consolidated clays using non-linear finite element method (FEM) and effective stress soil models to characterize the behavior of clay and unconsolidated shale formations. Two constitutive models are used: Modified Cam Clay (MCC; Roscoe and Burland, 1968), and MIT-E3 (Whittle and Kavvadas, 1994).
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44

Tivey, Hannah S. E. "Physiological responses to genomic instability." Thesis, Cardiff University, 2010. http://orca.cf.ac.uk/54394/.

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Abnormalities in the cellular senescence programme may contribute to premature ageing and cancer predisposition. Primary human cells have a limited proliferative capacity, entering a state of irreversible growth arrest/senescence arising from telomere attrition (replicative senescence). Stress-induced premature senescence (SIPS) can additionally limit cellular lifespan and there are several human genomic instability (Gl) disorders&mdash;cancer-prone/premature ageing syndromes&mdash;in which SIPS may prematurely limit cellular lifespan. The hypothesis is that increased Gl is a critical factor i
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Blakey, Caroline. "Anterior instability of the hip." Thesis, St George's, University of London, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676894.

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The evolution of humans to an upright stance has led to a change in the postural relationship between the human pelvis and the lower limb. However, despite the uncovering of the femoral head anteriorly, the bipedal hip remains inherently stable due to its bony anatomy and strong ligamentous support. Deviation from normal osseous anatomy results in a loss of constraint to dynamic movement with pathological translation of the femoral head (1,2). A similar scenario is expected with compromise of the surrounding soft tissue structures. A presentation of nine clinical cases describes the condition
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Tajik, Mohammad. "Banking instability : causes and remedies." Thesis, Brunel University, 2015. http://bura.brunel.ac.uk/handle/2438/10667.

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The recent U.S. subprime mortgage crisis rapidly spread throughout the world and put the global financial system under extraordinary pressure. The main implication of the recent crisis is that complex banking regulations failed to adequately identify and limit riskiness of banking systems at both domestic and international levels. In spite of a large empirical literature on the causes and remedies of the recent crisis, there remains substantial uncertainty on (i) how risk measuring models performed during crisis, (ii) how systematic factors such as house prices affected the financial system, a
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Kordesch, Wendy E. C. "Middle Eocene greenhouse climate instability." Thesis, University of Southampton, 2016. https://eprints.soton.ac.uk/402327/.

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Understanding warm climate states is increasingly important as projections of anthropogenic climate change indicate atmospheric carbon dioxide concentrations in the coming century not previously seen on Earth for tens of millions of years. The Eocene (~56-34 Ma) is a critical period in the long-term Cenozoic climate evolution, encompassing the transition from widespread greenhouse warmth and high atmospheric carbon dioxide levels pervasive during the early Eocene to an icehouse world with major Antarctic ice sheets and cooler temperatures. Increasingly, it has become apparent that global clima
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48

Gadgil, Rujuta Yashodhan. "Instability at Trinucleotide Repeat DNAs." Wright State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=wright1472231204.

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49

Santos, Tapia Celia. "Understanding chromosomal instability-induced senescence." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/671915.

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Aneuploidy, defined as a chromosome number that deviates from a multiple of the haploid set, is a common feature in human cancer, and around 70% of human solid tumours are aneuploid. The resulting metabolic imbalance is proposed to play a fundamental role in the compromised fitness of these cells and lead to malignant transformation by causing proteotoxic stress and affecting cell cycle proliferation and growth. However, most of the molecular pathways and cellular behaviours underlying aneuploid-induced tumorigenesis remain uncharacterized. Drosophila larval epidermal primordia have proved use
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50

Ismael, Mohanad. "Market imperfections and macroeconomic instability." Thesis, Evry-Val d'Essonne, 2011. http://www.theses.fr/2011EVRY0011/document.

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Dans cette thèse, on étudie l’effet de l’imperfection de marché sur la stabilité macroéconomique dans le modèle standard de Ramsey et celui de OLG. pour effectuer cette objective, on utilise la méthode de l’analyse de dynamique local lancé par Grandmont, Pintus et De Vilder (1998). les imperfections qu’on utilise sont les externalités en consommation, imperfection dans le marche de crédit, la présence de taxe progressive sur le revenu salariel et l’existence de coût de transaction associé avec l’accumulation de capital<br>In this thesis, we study the effect of market imperfection on macroecono
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