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1

Praveen Kumar, M., S. Suresh Kumar, and T. Munusamy. "INSTENT RESTENOSIS WITH BIFURCATION STENTING." Indian Heart Journal 75 (December 2023): S60. http://dx.doi.org/10.1016/j.ihj.2023.11.126.

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2

Chen, Yin, Shilian Hu, and Lei Wu. "Drug-eluting balloon for instent restenosis." Heart 99, no. 24 (2013): 1874.1–1874. http://dx.doi.org/10.1136/heartjnl-2013-304720.

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3

Bahl, Rahul, Andreas Indermuehle, Georg M. Froehlich, et al. "Drug-eluting balloon for instent restenosis." Heart 99, no. 24 (2013): 1874.2–1875. http://dx.doi.org/10.1136/heartjnl-2013-304722.

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4

Gonzalez, Alberto J., Michael A. Drummond, R. Scott McCord, and H. Edward Garrett. "Carotid Endarterectomy for Treatment of Instent Restenosis." Journal of Vascular Surgery 52, no. 6 (2010): 1742. http://dx.doi.org/10.1016/j.jvs.2010.10.025.

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5

Exner, Markus, Schila Sabet, Wolfgang Mlekusch, et al. "High plasma heparin cofactor II activity protects from restenosis after femoropopliteal stenting." Thrombosis and Haemostasis 92, no. 11 (2004): 1108–13. http://dx.doi.org/10.1160/th04-05-0311.

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SummaryHigh heparin cofactor II (HCII) activity has recently been described to protect from coronary instent restenosis, presumably by inactivating thrombin in injured arteries. In this study, we investigated the association of HCII activity and restenosis after femoropopliteal stenting. We studied 63 consecutive patients with peripheral artery disease who underwent femoropopliteal stent implantation after initial failure of plain balloon angioplasty due to a significant residual stenosis (>30% lumen diameter reduction) or a flow limiting dissection. HCII activity was measured before stenti
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6

Dussaillant, Gaston R., Gary S. Mintz, Augusto D. Pichard, et al. "A serial volumetricintravascular ultrasound analysis of instent restenosis." Journal of the American College of Cardiology 27, no. 2 (1996): 362. http://dx.doi.org/10.1016/s0735-1097(96)82365-5.

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7

Şabanoğlu, Cengiz, Esra Polat, and Elif İlkay Yüce. "The Association Between Coronary Instent Restenosis and Eosinophil/Monocyte Ratio." e-Journal of Cardiovascular Medicine 10, no. 3 (2022): 137–43. http://dx.doi.org/10.32596/ejcm.galenos.2022.2022-08-045.

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8

Akin, E., K. Knobloch, M. Pichlmaier, and A. Haverich. "Instent restenosis after carotid stenting necessitating open carotid surgical repair." European Journal of Cardio-Thoracic Surgery 26, no. 2 (2004): 442–43. http://dx.doi.org/10.1016/j.ejcts.2004.03.047.

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9

Tilara, Mandip, Rakesh Tirmale, and Sharad Jain. "Study of clinico-etiological profile of patients with instent restenosis." Indian Heart Journal 69 (November 2017): S62. http://dx.doi.org/10.1016/j.ihj.2017.09.181.

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10

Judkins, C., A. Wilson, and P. Barlis. "A Presentation on Lipid and Protein Markers of Instent Restenosis." Heart, Lung and Circulation 25 (August 2016): S163. http://dx.doi.org/10.1016/j.hlc.2016.06.384.

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11

Zeller, Thomas, Aljoscha Rastan, Uwe Schwarzwälder, et al. "Treatment of instent restenosis following stent-supported renal artery angioplasty." Catheterization and Cardiovascular Interventions 70, no. 3 (2007): 454–59. http://dx.doi.org/10.1002/ccd.21220.

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12

Hassid, Babak, Arber Kodra, Michael C. Kim, et al. "SAFETY AND EFFICACY OF INTRACORONARY BRACHYTHERAPY PROTOCOL FOR RESISTANT INSTENT RESTENOSIS." Journal of the American College of Cardiology 79, no. 9 (2022): 849. http://dx.doi.org/10.1016/s0735-1097(22)01840-x.

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13

Mastuda, Junji, Taishi Yonetsu, Tadashi Murai, et al. "COMPARISON BETWEEN ANGIOSCOPIC AND OPTICAL COHERENCE TOMOGRAPHIC ASSESSMENT OF INSTENT RESTENOSIS." Journal of the American College of Cardiology 69, no. 11 (2017): 298. http://dx.doi.org/10.1016/s0735-1097(17)33687-2.

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14

Shah, J., M. Sebastian, N. Andrianopoulos, et al. "How should we treat drug eluting stent (DES) instent restenosis (ISR)?" Heart, Lung and Circulation 24 (2015): S277. http://dx.doi.org/10.1016/j.hlc.2015.06.389.

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15

Engel, L., R. Adolf, I. Kringe, et al. "Identification Of Morphologic And Inflammatory Predictors Of Instent-Restenosis Using CCTA." Journal of Cardiovascular Computed Tomography 17, no. 4 (2023): S18. http://dx.doi.org/10.1016/j.jcct.2023.05.050.

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16

Siddiqui, Taha, Raiyan Ali, Shahan Haseeb, et al. "D-99 | The Burden of Instent Restenosis in Patients with MASLD." Journal of the Society for Cardiovascular Angiography & Interventions 4, no. 5 (2025): 103231. https://doi.org/10.1016/j.jscai.2025.103231.

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17

Jayaraj, Arjun, Robert Fuller, and Seshadri Raju. "Role of laser ablation in recalcitrant instent restenosis post iliofemoral venous stenting." Journal of Vascular Surgery Cases, Innovations and Techniques 7, no. 2 (2021): 298–301. http://dx.doi.org/10.1016/j.jvscit.2021.03.004.

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18

Amritphale, Amod. "Are Biodegradable Third Generation Drug Eluting Stents the Answer to Instent Restenosis?" Cardiology and Angiology: An International Journal 2, no. 1 (2014): 15–40. http://dx.doi.org/10.9734/ca/2014/9138.

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19

Mews, Geoffrey C., Geoffrey D. Cope, Richard A. Fox, et al. "A random placebo controlled trial of intracoronary RHENIUM-188 for instent restenosis." Heart, Lung and Circulation 12, no. 2 (2003): A97—A98. http://dx.doi.org/10.1046/j.1443-9506.2003.03672.x.

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20

Lee, Wei-Chieh. "TCT-406 The Predictors of Instent Restenosis Again After Drug Eluting Balloon." Journal of the American College of Cardiology 66, no. 15 (2015): B164—B165. http://dx.doi.org/10.1016/j.jacc.2015.08.420.

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21

Timizheva, K. B., A. V. Aghajanyan, L. V. Tskhovrebova, Z. Kh Shugushev, and M. M. Azova. "Assessment of the role of IL6 and IL10 gene polymorphisms as a risk factor for the development of restenosis in patients after implantation of drug-eluting stents." RUDN Journal of Medicine 25, no. 1 (2021): 48–54. http://dx.doi.org/10.22363/2313-0245-2021-25-1-48-54.

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Relevance. Currently, the number of percutaneous coronary interventions continues to increase, which leads to an increase in the absolute number of restenosis cases, which is the main complication of the long-term postoperative period. The search for risk factors responsible for restenosis and artery re-narrowing mechanisms in order to prevent this complication is an important goal in interventional cardiology. Risk factors for the restenosis development include clinical, angiographic and genetic factors. An active search for biomolecular markers associated with the coronary artery restenosis
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22

Schillinger, Martin. "How to treat recurrent renal artery instent restenosis? Editorial comment on treatment of reoccuring instent restenosis following reintervention after stent-supported renal artery angioplasty–Article by Zeller et al." Catheterization and Cardiovascular Interventions 70, no. 2 (2007): 301–2. http://dx.doi.org/10.1002/ccd.21294.

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23

Kaplan, Sahin, Peter Barlis, Jun Tanigawa, Omer Goktekin, and Carlo Di Mario. "Unconventional treatment of aorto-ostial instent restenosis with marked protrusion into the aorta." Journal of Cardiovascular Medicine 9, no. 2 (2008): 184–86. http://dx.doi.org/10.2459/jcm.0b013e3280126208.

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24

Jensen, L. O., P. Thayssen, J. F. Lassen, et al. "Recruitable collateral blood flow index predicts coronary instent restenosis after percutaneous coronary intervention." European Heart Journal 28, no. 15 (2007): 1820–26. http://dx.doi.org/10.1093/eurheartj/ehm067.

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25

Mehran, Roxana, Gary S. Mintz, Jeffrey J. Popma, et al. "Excimer laser angioplasty in the treatment of instent restenosis: An intravascular ultrasound study." Journal of the American College of Cardiology 27, no. 2 (1996): 362. http://dx.doi.org/10.1016/s0735-1097(96)82364-3.

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26

Ghoshal, A., and A. Mishra. "Outcomes of drug eluting balloon in native coronaries & venous graft instent restenosis." Heart, Lung and Circulation 24 (2015): S158. http://dx.doi.org/10.1016/j.hlc.2015.06.108.

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27

Zeller, Thomas, Sebastian Sixt, Aljoscha Rastan, et al. "Treatment of reoccurring instent restenosis following reintervention after stent-supported renal artery angioplasty." Catheterization and Cardiovascular Interventions 70, no. 2 (2007): 296–300. http://dx.doi.org/10.1002/ccd.21170.

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28

Böhme, Tanja, Elias Noory, Ulrich Beschorner, et al. "Photoablative atherectomy followed by a paclitaxel-coated balloon to inhibit restenosis in instent femoro-popliteal obstructions (PHOTOPAC)." Vasa 50, no. 5 (2021): 387–93. http://dx.doi.org/10.1024/0301-1526/a000959.

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Summary: Background: To evaluate the safety and effectiveness of preparing instent femoropopliteal lesion with photoablative laser atherectomy or plain balloon angioplasty (POBA) prior to drug-coated balloon (DCB) angioplasty. Patients and methods: The prospective, multicenter, randomized study enrolled patients with Rutherford-Becker-class (RBC) 1 to 5 and instent lesions located in superficial femoral artery and/or popliteal artery above the knee joint. Primary endpoint was target lesion percent stenosis at 1 year as determined by the angiographic core-laboratory. Secondary endpoints include
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29

Sakai, Hidetsugu, Naotsugu Oyama, Noriaki Kishimoto, Masashige Takahashi, Kazushi Urasawa, and Hiroyuki Tsutsui. "Revascularization of Malignant Coronary Instent Restenosis Resulting From Takayasu's Arteritis Using Sirolimus-Eluting Stents." International Heart Journal 47, no. 5 (2006): 795–801. http://dx.doi.org/10.1536/ihj.47.795.

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30

Xu, Jack, Michael S. Cross, Swetal Patel, and Subhi Jamal Alaref. "UTILIZING SHOCKWAVE THERAPY FOR THE TREATMENT OF RECURRENT INSTENT RESTENOSIS AND SIGNIFICANT CORONARY CALCIFICATION." Journal of the American College of Cardiology 79, no. 9 (2022): 2284. http://dx.doi.org/10.1016/s0735-1097(22)03275-2.

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31

Taniwaki, Masanori, Keiichi Onishi, Hirotaka Ezaki, et al. "PERFORMANCE OF ULTRA-HIGH RESOLUTION CT OF INSTENT RESTENOSIS OF BELOW 3.0MM CORONARY STENT." Journal of the American College of Cardiology 75, no. 11 (2020): 1629. http://dx.doi.org/10.1016/s0735-1097(20)32256-7.

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32

Mahdi, N. "PTCA, Directional and Rotational Coronary Atherectomy in the Management of Palmaz-Schatz Instent Restenosis." Journal of the American College of Cardiology 31, no. 2 (1998): 275A. http://dx.doi.org/10.1016/s0735-1097(97)84905-4.

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33

Swinnen, Jan “John”, Kerry Hitos, Lukas Kairaitis, et al. "Multicentre, randomised, blinded, control trial of drug-eluting balloon vs Sham in recurrent native dialysis fistula stenoses." Journal of Vascular Access 20, no. 3 (2018): 260–69. http://dx.doi.org/10.1177/1129729818801556.

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Background: Endovascular treatment of autogenous arteriovenous haemodialysis fistula stenosis has high reintervention rates. We investigate the effect of drug-eluting balloons in the treatment of recurrent haemodialysis fistula stenosis. Methods: This is a randomised, controlled, investigator-initiated and run, prospective, blinded, multicentre trial. Patients with recurrent autogenous arteriovenous haemodialysis fistula stenosis received standard endovascular treatment plus drug-eluting balloon or standard endovascular treatment plus uncoated balloon (Sham). Primary endpoint was late lumen lo
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34

Chandrasekar, Baskaran, Martin Sirois, Pascale Geoffroy, Dominique Lauzier, Stanley Nattel та Jean-François Tanguay. "Local delivery of 17β-estradiol improves reendothelialization and decreases inflammation after coronary stenting in a porcine model". Thrombosis and Haemostasis 94, № 11 (2005): 1042–47. http://dx.doi.org/10.1160/th04-12-0823.

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SummaryIn the current study, we investigated the effect of local intravascular delivery of 17β-estradiol (17β-E) on subsequent instent neointimal hyperplasia. Twenty-seven stents were implanted in coronary arteries of juvenile swine. Coronary arteries were randomized to local treatment with 17β-E or no drug therapy (control-vehicle treated). Twenty-eight days posttreatment, angiographic images revealed an improved minimal lumen diameter (2.2 ± 0.2 vs. 1.3 ± 0.2 mm, P < 0.005) and a reduction of late lumen loss (1.7 ± 0.2 vs. 2.3 ± 0.1 mm, P < 0.01) in 17β-E-treated vessels compared to co
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35

Liang, Dongke, Da Zhi Yang, Min Qi, and Wei Qiang Wang. "Finite Element Analysis of a Stent Implantation in a Stenosed Artery." Key Engineering Materials 288-289 (June 2005): 571–74. http://dx.doi.org/10.4028/www.scientific.net/kem.288-289.571.

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Instent restenosis (ISR) has been a key factor that restricts the further use of intraoronary stents. And the mechanical interaction between the stent and the artery has been indicated as one of the significant causes for the activation of stent-related restenosis. However, there is very little quantitative information about the interaction of stent with artery. In order to improve the general understanding of coronary stenting, finite element method (FEM) has been used to model the revascularization of a stenosed artery through the insertion of a balloon-expandable stent. Given a stent design
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36

Sadato, A., W. Taki, N. Sakai, et al. "Initial Experiences of Carotid Stenting with Palmaz Stent." Interventional Neuroradiology 5, no. 1_suppl (1999): 33–35. http://dx.doi.org/10.1177/15910199990050s105.

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Results of cervical carotid stenting are reported. Twenty-nine lesions in 25 cases were treated by percutaneous transluminal balloon angioplasty combined with stent placement. All the lesions were successfully dilated. There was one embolic complication during the operation that caused deterioration of preoperative symptoms. Stent deformation causing more than 30% luminal narrowing occurred in one case. Instent restenosis with more than 50% luminal narrowing was seen in bilateral lesions in one case. These were satisfactory results as an initial experience, but further improvement in this tech
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37

YIN, Yu-gang, and Bin WANG. "Effects of rosuvastatin on instent restenosis, plasma lipid level and inflammatory factors after coronary stenting." Academic Journal of Second Military Medical University 31, no. 2 (2011): 227–28. http://dx.doi.org/10.3724/sp.j.1008.2011.00227.

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38

Jayaraj, Arjun, and Seshadri Raju. "Utility of a Mechanical Thrombectomy Device in Treating Calcified Instent Restenosis Post Iliofemoral Venous Stenting." Annals of Vascular Surgery 79 (February 2022): 443.e1–443.e5. http://dx.doi.org/10.1016/j.avsg.2021.08.020.

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39

Wei, X., Y. Zheng-Bai, S. Zhen-Qi, and H. Hong-Hua. "Influence of the level of HB-EGF in serum on instent restenosis after CHD stenting." Heart 97, Suppl 3 (2011): A167. http://dx.doi.org/10.1136/heartjnl-2011-300867.495.

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40

Varenhorst, Christoph, Giovanna Sarno, Kristina Hambraeus, et al. "SCAAR: CHANGES IN DRUG ELUTING STENT USE AND INSTENT-RESTENOSIS RATES FROM 2002 TO 2012." Journal of the American College of Cardiology 63, no. 12 (2014): A1902. http://dx.doi.org/10.1016/s0735-1097(14)61905-7.

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41

Chua, Dave C. Y., Francis Q. Almeda, Shaun Senter та ін. "Visual assessment of procedural results following treatment with Sr-90 β-radiation for instent restenosis". Cardiovascular Radiation Medicine 3, № 3-4 (2002): 133–37. http://dx.doi.org/10.1016/s1522-1865(03)00102-1.

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42

Chua, Dave C. Y., Francis Q. Almeda, Shaun Senter та ін. "Predictors of late cardiac events following treatment with Sr-90 β-irradiation for instent restenosis". Cardiovascular Radiation Medicine 4, № 1 (2003): 7–11. http://dx.doi.org/10.1016/s1522-1865(03)00117-3.

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43

Lin, Chia-Chang, and Jun-Ting Liou. "TCTAP C-058 Severe BMS-Instent Restenosis Treated by Cutting & Drug-coated Balloon Dilatations." Journal of the American College of Cardiology 73, no. 15 (2019): S128—S129. http://dx.doi.org/10.1016/j.jacc.2019.03.246.

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44

Montrivade, Sakolwat. "TCTAP C-083 Solving Recalcitrant Instent Restenosis With Combined Laser Atherectomy and Shockwave Intravascular Lithotripsy." Journal of the American College of Cardiology 83, no. 16 (2024): S175—S177. http://dx.doi.org/10.1016/j.jacc.2024.03.190.

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45

Zhou, Sheng-Nan, Le Yang, Bi-Yang Feng, Lei Liu, and Li-Ming Chen. "In-Stent Restenosis: Achilles’ Heel of Post-PCI Era." Journal of Clinical Cardiology 5, no. 1 (2024): 1–5. http://dx.doi.org/10.33696/cardiology.5.047.

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Despite advancements in stent design and polymer coatings over the past two decades, 1% to 2% of patients annually still experience instent restenosis (ISR). ISR reduces myocardial perfusion, may develop symptoms of myocardial ischemia, and thus leads to a high risk of myocardial infarction and cardiac death. Given that millions of drug-eluting stents (DES) are implanted globally every year, ISR remains a prevalent clinical issue with significant public health implications. Coronary intravascular imaging, includes intravascular ultrasound (IVUS) and optical coherence tomography (OCT), can help
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46

Skoczyńska, Agnieszka, Andrzej Ochała, Sebastian Dworowy, and Michał Tendera. "Drug eluting stent or drug eluting balloon? Which is the better device to treat instent restenosis?" Advances in Interventional Cardiology 2 (2011): 147–55. http://dx.doi.org/10.5114/pwki.2011.23167.

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47

Heck, D. "033 Incidence and time course of carotid instent restenosis in a consecutive series of 295 patients." Journal of NeuroInterventional Surgery 1, no. 1 (2009): 86–87. http://dx.doi.org/10.1136/jnis.2009.001016g.

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48

Fujiu, Katsuhito, Ichiro Manabe, Yumiko Oishi, Kensuke Tsushima, Go Nishimura, and Ryozo Nagai. "ADMINISTRATION OF AM80 INHIBITED INSTENT RESTENOSIS BY MODULATING SMOOTH MUSCLE CELL PHENOTYPE IN VITRO AND VIVO." Cardiovascular Pathology 13, no. 3 (2004): 159. http://dx.doi.org/10.1016/j.carpath.2004.03.480.

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49

Oruganti, Harish. "TCTAP C-110 Look Beyond What You See: Successful Oct Guided PCI of Lad Instent Restenosis." Journal of the American College of Cardiology 85, no. 15 (2025): S262—S265. https://doi.org/10.1016/j.jacc.2025.03.261.

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50

Rittger, H., M. Waliszewski, J. Woehrle, et al. "Prediction of therapy failure after treatment of instent-restenosis of drug-eluting stents with drug coated balloons." European Heart Journal 34, suppl 1 (2013): P4801. http://dx.doi.org/10.1093/eurheartj/eht310.p4801.

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