Relevant bibliographies by topics / Instituto de neurología

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Instituto de neurología'

Author: Grafiati
Published: 26 July 2024

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Journal articles on the topic "Instituto de neurología"

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Nava Galán, Ma Guadalupe. "La certificación en el Instituto Nacional de Neurología y Neurocirugía / Certification in the National Institute of Neurology and Neurosurgery." Revista de Enfermería Neurológica 10, no. 1 (June 30, 2011): 4. http://dx.doi.org/10.37976/enfermeria.v10i1.125.

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Realizar trabajo en equipo es la clave para generar un ambiente de calidad en el Instituto Nacional de Neurología y Neurocirugía, con acciones responsables a través de la implantación de un sistema de seguridad y de una excelente atención; así se plasma la política de calidad que cada uno de sus integrantes brinda, al implantar un sistema de seguridad y una excelente atención, formación e investigación.
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Moreno-Zambrano, Daniel, Joffre A. Wong-Ayoub, Martha Arevalo-Mora, Iliana San Andrés-Suárez, David Santana, Joyce Meza-Venegas, Eric Urquizo-Rodríguez, Joyce Jimenez-Zambrano, and Rocio Garcia-Santibanez. "Number of Neurologists and Neurology Training Programs available in the Public Health System of Ecuador: Analysis and Recommendation." Revista Ecuatoriana de Neurologia 32, no. 2 (November 5, 2023): 55–60. http://dx.doi.org/10.46997/revecuatneurol32200055.

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Introducción: En el 2008, el perfil de salud neurológico ecuatoriano presentaba importantes déficits, escasez de neurólogos e inaccesibilidad a residencias en neurología. Ese año una nueva constitución introdujo atención médica universal. Ninguna publicación ha analizado la capacidad de atención neurológica del Sistema de Salud Pública (SSP) del Ecuador. Un análisis actualizado del número de neurólogos y residencias neurológicas es necesario. Objetivo: Determinar el número de programas en neurología y si el SSP ecuatoriano cumple con el ratio ideal mínimo recomendado por la Organización Mundial de la Salud de 1 neurólogo por cada 100.000 habitantes. Métodos: Análisis transversal de datos hasta noviembre, 2022 del SSP y del Consejo de Educación Superior del Ecuador. Los ratio se calcularon acorde al Instituto Nacional de Estadística y Censos. Resultados: El SSP cuenta con noventa y cuatro neurólogos. Mayormente en Pichincha (37/39,4%) y Guayas (24/25,5%). Hay uno por provincia en cinco provincias; ninguno en ocho provincias. Dos provincias cumplieron el ratio ideal. Existen 0,54:100.000 neurólogos/habitantes y una residencia de neurolog ía en Quito. Conclusión: El SSP ecuatoriano tiene escasez de neurólogos, incumpliendo el ratio ideal mínimo, y déficit de residencias en neurología. La descentralización de servicios neurológicos, soporte atención primaria, y financiamiento gubernamental para creación de residencias en neurología son necesidades urgentes.
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Jiménez-López, Erandi Jimena, Ana Cecilia Rodríguez-de Romo, and Gabriela Castañeda-López. "La historia del Instituto Nacional de Neurología y Neurocirugía a través de un documento." Archivos de Neurociencias 19, no. 1 (March 1, 2014): 67–70. http://dx.doi.org/10.31157/an.v19i1.34.

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En 1970, la trabajadora social María Luisa Flores González visitó el Hospital Granja “Bernardino Álvarez”, ubicado en el terreno que ocupa el Instituto Nacional de Neurología y Neurocirugía, con la idea de instalar en su lugar un “Taller protegido” para débiles mentales. El proyecto no se realizó. Los detalles de la visita aparecen en un documento original resguardado en el Archivo Histórico de la Secretaria de Salud, que aquí se reproduce porque da evidencia de detalles interesantes acerca de los antecedentes del Instituto que en 2014 cumplirá cincuenta años de haberse fundado.
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Jiménez-López, Erandi Jimena, Ana Cecilia Rodríguez-de Romo, and Gabriela Castañeda-López. "La historia del Instituto Nacional de Neurología y Neurocirugía a través de un documento." Archivos de Neurociencias 19, no. 1 (March 1, 2014): 67–70. http://dx.doi.org/10.31157/archneurosciencesmex.v19i1.34.

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En 1970, la trabajadora social María Luisa Flores González visitó el Hospital Granja “Bernardino Álvarez”, ubicado en el terreno que ocupa el Instituto Nacional de Neurología y Neurocirugía, con la idea de instalar en su lugar un “Taller protegido” para débiles mentales. El proyecto no se realizó. Los detalles de la visita aparecen en un documento original resguardado en el Archivo Histórico de la Secretaria de Salud, que aquí se reproduce porque da evidencia de detalles interesantes acerca de los antecedentes del Instituto que en 2014 cumplirá cincuenta años de haberse fundado.
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Para la Investigación en Neurociencias, Fundación CENIT. "Latin American Congress of Functional Neurosurgery and Stereotaxy. Presentation Summaries." NeuroTarget 9, no. 2 (May 1, 2015): 38–39. http://dx.doi.org/10.47924/neurotarget2015245.

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Consideraciones en malformaciones arteriovenosas cerebralesHenin Mora Benites, MD. NeurocirujanoUnidad de Radiocirugía Gammaknife Center, Hospital Clínica Alcívar, Guayaquil, Ecuador. E-mail: heninmora@hotmail.com Radiocirugía fraccionada, aplicaciones actualesGustavo Zomosa R., MDDepartamento de Neurología-Neurocirugía Hospital Clínico, Universidad de Chile, Centro de costos Radioterapia Radiocirugía, Instituto Nacional del Cáncer, Gamma Knife Chile, Santiago de Chile. E-mail: gzomosar@hotmail.com
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Valdez Labastida, Rocio, Patricia Zamora Ruiz, Blanca-E. Reyes Chávez, and Guisety López-Cantera. "Consultoría en enfermería, una estrategia de cuidado avanzado." Revista de Enfermería Neurológica 16, no. 3 (December 31, 2017): 159–66. http://dx.doi.org/10.37976/enfermeria.v16i3.246.

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Objetivos: describir el impacto de la consultoría neurológica, en el Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez (INNyN MVS), mediante su relación con el número de reingresos hospitalarios por mal cuidado en el hogar. Material y métodos: se trata de un estudio descriptivo, observacional, transversal y retrospectivo donde se incluye una muestra de 146 pacientes atendidos en consultoría neurológica en el periodo enero 2015 a marzo 2016, de cada uno de ellos se estudió la variable: reingreso hospitalario en el Instituto Nacional de Neurología y Neurocirugía MVS. Los datos se procesaron en el paquete estadístico SPSS y, para su análisis, en Excel. Resultados: se atendieron 146 pacientes a los que se otorgaron un total de 524 consultas, con un promedio de 3.6 consultas por paciente. Se encontró que el porcentaje de reingresos es de 27.4% de los cuales el 10.9% reingresaron por mal cuidado en el hogar, principalmente con diagnósticos de: Ulceras por Presión (UPP), deshidratación, desnutrición e infecciones y otros. Conclusiones: la Consultoría de especialidad permitirá desarrollar un modelo de atención, de enfermería neurológica, que no sólo contribuya con la demanda de atención disminuyendo reingresos sino que modifique, mejorando las condiciones clínicas del paciente dentro y fuera de la institución, y disminuya costos y favorezca la calidad de vida.
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Nava Galán, Ma Guadalupe. "Desafíos de la Unidad de Investigación del Instituto Nacional de Neurología y Neurocirugía." Revista de Enfermería Neurológica 12, no. 3 (December 31, 2013): 159–63. http://dx.doi.org/10.37976/enfermeria.v12i3.174.

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El surgimiento de la investigación en enfermería inició con los registros detallados de las observaciones de Florencia Nightingale, quien aplicó sus conocimientos al estudio de la realidad a través de la historia y la filosofía. Esto constituyó el centro de su vida, es decir, el cuidado de la salud de las personas. Ella analizó la lógica del pensamiento de enfermería, las bases filosóficas, epistemológicas y éticas a través de su teoría, a partir del análisis del contexto histórico sociocultural en el cual se desarrolló su principal obra. Sus bitácoras están plasmadas a través de sus notas -éstas parten de la lógica del pensamiento Nightingaleano- las cuales han servido de punto de partida para desarrollar todas y cada una de las actuales teorías de enfermería. Sobre todo, Florencia Nightingale merecen el profundo reconocimiento de haber sido la pionera del pensamiento científico, así como de cuestiones éticas en enfermería y del desarrollo disciplinar actual.
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Nava Galán, Ma Guadalupe. "Implementación de las 10 estrategias por la seguridad del paciente en el Instituto Nacional de Neurología y Neurocirugía." Revista de Enfermería Neurológica 12, no. 3 (December 31, 2013): 116–17. http://dx.doi.org/10.37976/enfermeria.v12i3.166.

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La Organización Mundial de la Salud (OMS), a través de su dirección general, pone en marcha en octubre de 2004 la Alianza Mundial para la Seguridad del Paciente. Este organismo es un medio que propicia la colaboración internacional y la acción de los Estados Miembros, a través de la OMS y de los expertos, usuarios y grupos de profesionales en las Instituciones de Salud, como lo hace el Instituto Nacional de Neurología y Neurocirugía.
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Nava Galán, Ma Guadalupe. "Certificación del Instituto Nacional de Neurología y Neurocirugía por la Joint Commission International Certification of the National Institute for Neurology and Neurosurgery Joint Commission International." Revista de Enfermería Neurológica 10, no. 2 (December 31, 2011): 62. http://dx.doi.org/10.37976/enfermeria.v10i2.128.

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La Organización Panamericana de la Salud (OPS) tuvo la iniciativa de impulsar la acreditación de los hospitales en América Latina; a principios de los 90, en México, el Consejo de Salubridad General (CSG) implementa los sistemas de certificación y “acreditación”. El Tratado de Libre Comercio en América del Norte y la cercanía con Estados Unidos y Canadá, además de la clara tendencia hacia la globalización en múltiples ámbitos de la economía, han impulsado la necesidad de establecer estándares de calidad equivalentes entre países.
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Sánchez Bermúdez, Claudia, and Ma Guadalupe Nava Galán. "Factores que influyen en la automedicación del personal de enfermería a nivel técnico y de estudiantes." Revista de Enfermería Neurológica 11, no. 2 (August 31, 2012): 120–28. http://dx.doi.org/10.37976/enfermeria.v11i2.141.

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La automedicación, es "el consumo de medicamentos, hierbas y remedios caseros por iniciativa o consejo de otra persona, sin consultar al médico", considerada también como un fenómeno que se ha incrementado a través del tiempo, convirtiéndose en un serio problema de salud pública. En México no existen estudios o publicaciones que permitan valorar la real magnitud de esta práctica en la población. Objetivo: Conocer los factores que influyen en la automedicación del personal de enfermería a nivel técnico y estudiantes del Instituto Nacional de Neurología y Neurocirugía.
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Dissertations / Theses on the topic "Instituto de neurología"

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Enciso, Matos Ivan. "Etiología de la enfermedad cerebro vascular isquémica en adultos jóvenes: hospitalizados en el Instituto Nacional de Ciencias Neurológicas en el periodo 2010 - 2013." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2014. https://hdl.handle.net/20.500.12672/10235.

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Determina la etiología de la enfermedad cerebro vascular isquémica en los adultos jóvenes hospitalizados en el departamento de enfermedades neurovasculares del Instituto Nacional de Ciencias Neurológicas durante el periodo 2010 al 2013. Se realizó un estudio observacional, transversal de casos. Se revisaron 43 de pacientes jóvenes que presentaron desorden cerebrovascular isquémico, en el Servicio de neurología del Instituto Nacional de Ciencias Neurológicas en el periodo que correspondió al estudio. Del 55.8% eran mujeres y el 44.2% eran varones. La media de la edad de los varones fue de 37.3+/-6.6 años y de las mujeres fue de 37.9+/-6.4 años, siendo la media global de 37.6+/-6.4 años. El 69.8% de los pacientes provenían de Lima. Hubo una mayor frecuencia de etiología cardioembólica en el 23.3% de los casos. El 44.2% de los pacientes no tenían causa indeterminada. El 52.6% de los varones tuvo etiología indeterminada, seguido de un 15.8% de etiología cardioembólica y aterotrombótica respectivamente. En las mujeres el 37.5% tuvo etiología indeterminada, seguido del 29.2% que tuvo etiología cardioembólica. Hubo una mayor media de la edad en los pacientes que tuvieron etiología aterotrombótica (41.8 años), y una menor edad en los pacientes cuya etiología fue indeterminada (34.7 años). El territorio comprometido con mayor frecuencia en los pacientes adultos jóvenes con ECV isquémico fue la circulación anterior parcial en un 65.1% de los casos. Se concluye que la etiología de la enfermedad cerebro vascular isquémica de mayor frecuencia en los adultos jóvenes hospitalizados en el departamento de enfermedades neurovasculares del Instituto Nacional de Ciencias Neurológicas fue la etiología no determinada y la cardioembólica. La etiología del ECV isquémico en adultos jóvenes con migraña (indeterminado), uso de anticonceptivos (indeterminado), tabaquismo (aterotrombótico) y trastornos de coagulación (inhabitual).La frecuencia de ECV isquémico en adultos jóvenes según sexo fue indeterminada.No hubo mortalidad en la población estudiada. El territorio cerebral comprometido con mayor frecuencia fue la circulación anterior parcial. Los exámenes auxiliares utilizados con mayor frecuencia fueron la TAC, Eco carotidea, ETT, Holter, RM. La mayoría de pacientes provenían de Lima.
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Aramburú, Miranda Nátaly Claudia. "Factores asociados a evolución adversa en pacientes menores de 15 años con diagnóstico de estado epiléptico convulsivo hospitalizados en el Instituto Nacional de Salud del Niño durante el periodo 2008-2013." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2014. https://hdl.handle.net/20.500.12672/9080.

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Determina los factores asociados a evolución adversa neurológica en pacientes menores de 15 años con diagnóstico de estado epiléptico convulsivo hospitalizados en el Instituto Nacional de Salud del Niño durante el periodo 2008-2013. Es un estudio analítico, restrospectivo, tipo casos y controles. La población de estudio incluye a todos los niños de 2 meses de edad hasta los 15 años ingresados para hospitalización. Los casos son definidos como aquellos pacientes que presentan secuela. Las secuelas son clasificadas como secuelas neurológicas mayores y menores, discapacidad neurológica aumentada y fallecimiento. Se revisan 144 historias clínicas que cumplían los criterios de selección definidos, de estos 36 son definidos como casos y 108 como controles. La mayoría era del sexo masculino, con una edad promedio de 4,8 – 5,8 años. La mayoría presentaba alguna comorbilidad neurológica, siendo la más frecuente la epilepsia. La etiología sintomática remota es la más frecuente. La mayoría es atendida en base a un manejo hospitalario de primera y segunda línea. La secuela neurológica más frecuente es el RDPM. La mortalidad es nula. La duración del EEC mayor a 30 minutos presenta una asociación significativa como factor de riesgo para secuelas neurológicas. La duración del EEC mayor a 30 minutos muestra una asociación significativa para el desarrollo de secuelas neurológicas.
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Goede, Lukas Laurids [Verfasser], and Karin [Akademischer Betreuer] Weißenborn. "Analyse mikrostruktureller Veränderungen des Gehirns unter langfristiger Therapie mit Calcineurininhibitoren nach Lebertransplantation mittels quantitativer Magnetresonanztomografie / Lukas Laurids Goede ; Akademischer Betreuer: Karin Weißenborn ; Klinik für Neurologie, Institut für Diagnostische und Interventionelle Neuroradiologie." Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2021. http://d-nb.info/1236024265/34.

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Silva, Adriana Henriques. "NIHSS underestimates right hemisphere stroke injury : raising an old issue with a new cognitive approach." Master's thesis, 2021. http://hdl.handle.net/10451/51150.

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Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2021
Introdução: A escala de acidente vascular cerebral (AVC) do National Institute of Health (NIHSS) é uma ferramenta de quantificação da gravidade de um AVC. Apesar de amplamente utilizada, estudos sugerem que não avalia igualmente os 2 hemisférios cerebrais. Pensa-­‐se que o NIHSS subestima o volume das lesões do hemisfério direito possivelmente devido ao facto de 2 pontos serem atribuídos ao neglect e 7 às alterações de linguagem. Embora o NIHSS de doentes com neglect possa sugerir melhor outcome funcional comparativamente com doentes com afasia, estudos demonstram que o neglect está associado a piores outcomes. Objetivos: Comparar as correlações entre o volume da lesão e o NIHSS de doentes com neglect e sem neglect e estudar se uma modificação das regras de pontuação de neglect no NIHSS aumentaria a sua capacidade de predição do volume de lesão. Métodos: A amostra de doentes com AVC na artéria cerebral média direita foi dividida 2 grupos: doentes com neglect e sem neglect. Comparámos as correlações entre o volume de lesão e o NIHSS dos grupos e calculámos a correlação parcial entre o volume da lesão, NIHSS e a variável ter ou não neglect. Estudamos ainda diferentes modificações das regras de pontuação de neglect e repetimos a análise. Resultados: A correlação entre volume de lesão e NIHSS foi menor em doentes com neglect e a correlação parcial entre volume de lesão e a variável grupo, controlando o NIHSS, foi estatisticamente significativa. Com a pontuação de neglect triplicada e com a soma de todas as modalidades de neglect duplicada e triplicada, a correlação entre o volume da lesão e o NIHSS foi significativamente maior do que com o NIHSS original e a correlação parcial deixou de ser estatisticamente significativa.
Background: The National Institutes of Health Stroke Scale (NIHSS) is a widely used tool for quantification of stroke severity. However, prior studies suggest that this scale does not equitably assess the 2 hemispheres, reporting that the volume of right hemisphere (RH) lesions is underestimated. This is probably due to the fact that NIHSS attributes 2 points for neglect and 7 for language. While empirical assessment could suggest better functional outcomes for patients with neglect than for those with aphasia, some authors have reported that neglect is associated with worse functional outcomes. Objectives: The aims were: a) to compare the correlations between the lesion volume of RH stroke and the NIHSS score from patients with neglect and without neglect and b) to study if a modification of the neglect scoring rules would increase the predictive capacity of the lesion volume. Methods: Patients with right middle cerebral artery ischemic stroke were divided in two groups: patients with neglect and patients without neglect at admission. We correlated NIHSS scores and lesion volume in both groups and calculated the partial correlation between lesion volume, NIHSS and the variable group. Finally, we applied different modifications in the neglect scoring rules and repeated the statistical analysis. Results: The correlation between lesion volume and NIHSS was lower in patients with neglect and neglect was a statistically significant covariate in the partial correlation analysis between NIHSS and lesion volume. With the neglect score tripled and with the sum of all neglect modalities doubled and tripled, the correlation between lesion volume and NIHSS was significantly higher than the correlation with the standard NIHSS and the partial correlation between lesion volume and the variable group, controlling for NIHSS, became no longer a statistically significant factor.
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Books on the topic "Instituto de neurología"

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Max-Planck-Institut. Max-Planck-Institut für Neurologische Forschung. München: Max-Planck-Gesellschaft, 1992.

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The Neurological Institute of New York: The first hundred years. [New York]: [Neurological Institute], 2009.

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Arosio, Franco. Carlo Besta and the foundation of the National Neurological Institute in Milan. Milan: "Carlo Besta" National Neurological Institute, 1993.

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Arosio, Franco. Carlo Besta (1876-1940): And the foundation of the National Neurological Institute of Milan. 2nd ed. Milan: "Carlo Besta" National Neurological Institute, 2000.

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Rowland, Lewis P. NINDS at 50: An incomplete history celebrating the fiftieth anniversary of the National Institute of Neurological Disorders and Stroke. Bethesda, Md: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 2001.

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United States. National Advisory Mental Health Council, ed. Approaching the 21st century: Opportunities for NIMH neuroscience research. Rockville, Md: U.S. Department of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute of Mental Health, 1988.

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Arosio, Franco. Carlo Besta, 1876-1940. Milano: Istituto nazionale neurologico "Carlo Besta", 1997.

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Arosio, Franco. Carlo Besta, 1876-1940. Milano: Istituto nazionale neurologico "Carlo Besta", 1993.

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Arosio, Franco. Carlo Besta (1876-1940) and the foundation of the National Neurological Institute of Milan. 2nd ed. Milan: "Carlo Besta" National Neurological Institute, 2000.

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Arosio, Franco. Carlo Besta (1876-1940) and the foundation of the National Neurological Institute of Milan. 2nd ed. Milan: "Carlo Besta" National Neurological Institute, 2000.

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Book chapters on the topic "Instituto de neurología"

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Magoun, Horace W. "The Role of Research Institutes in the Advancement of Neuroscience: Ranson’s Institute of Neurology, 1928–1942." In The Neurosciences: Paths of Discovery, I, 515–27. Boston, MA: Birkhäuser Boston, 1992. http://dx.doi.org/10.1007/978-1-4612-2970-4_28.

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Magoun, Horace W. "The Role of Research Institutes in the Advancement of Neuroscience: Ranson’s Institute of Neurology, 1928–1942." In The Neurosciences: Paths of Discovery, I, 515–27. Boston, MA: Birkhäuser Boston, 1992. http://dx.doi.org/10.1007/978-1-4684-6817-5_28.

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Kreft, G. "The Work of Ludwig Edinger and His Neurology Institute." In Neuroendocrinology, 407–23. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60915-2_31.

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Flinsenberg, Ingrid, Roel Cuppen, Evert van Loenen, Elke Daemen, and Roos Rajae-Joordens. "Context-Aware System for Neurology Hospital Wards." In Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering, 366–73. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-29734-2_50.

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Kovai, Melinda. "The History of the Hungarian Institute of Psychiatry and Neurology between 1945 and 1968." In Psychiatry in Communist Europe, 117–33. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1007/978-1-137-49092-6_6.

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Islam, Saiful, Saiam Ahmed, Rosamund Greiner, Shah-Jalal Sarker, Mifuyu Akasaki, Masuda Khanom, David Blundred, Alessandro Cozzi-Lepri, and Yasna Palmeiro-Silva. "COVID-19: Online Not Distant—MSc Students’ Feedback on an Alternative Approach to Teaching ‘Research Methods and Introduction to Statistics’ at UCL Queen Square Institute of Neurology." In Teaching Biostatistics in Medicine and Allied Health Sciences, 111–20. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-26010-0_8.

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Saccardi, Riccardo, and Fermin Sanchez-Guijo. "How Can Accreditation Bodies, Such as JACIE or FACT, Support Centres in Getting Qualified?" In The EBMT/EHA CAR-T Cell Handbook, 199–201. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94353-0_38.

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AbstractThe FACT-JACIE accreditation system is based on a standard-driven process covering all the steps of HSC transplant activity, from donor selection to clinical care. Since the first approval of the First Edition of the Standards in 1998, over 360 HSCT programmes or facilities have been accredited at least once, most of them achieving subsequent re-accreditations (Snowden et al. 2017). The positive impact of the accreditation process in the EBMT Registry has been well established (Gratwohl et al. 2014). Starting with version 6.1, the standards include new items specifically developed for other cellular therapy products, with special reference to immune effector cells (IECs). This reflects the rapid evolution of the field of cellular therapy, primarily (but not exclusively) through the use of genetically modified cells, such as CAR-T cells. FACT-JACIE standards cover a wide range of important aspects that can be of use for centres that aim to be accredited in their countries to provide IEC therapy. Notably, FACT-JACIE accreditation itself is a key (or even a prerequisite) condition in some countries for approval by health authorities to provide commercial CAR-T cell therapy and is also valued by pharmaceutical companies (both those developing clinical trials and those manufacturing commercial products), which also inspect the cell therapy programmes and facilities established at each centre (Yakoub-Agha et al. 2020). Interest in applying for FACT-JACIE accreditation that includes IEC therapeutic programmes is clearly increasing, from four applications in 2017 to 36 applications approved in 2019. The standards do not cover the manufacturing of such cells but include the chain of responsibilities when the product is provided by a third party (Maus and Nikiforow 2017). In any case, all the steps in the process in which the centre is involved (e.g., patient or donor evaluations, cell collection, cell reception, and storage) are covered by the standards, including the appropriate agreements with the internal partners, including the pharmacy department. In addition, from a clinical perspective, IECs may require special safety monitoring systems due to the high frequency of acute adverse events related to the massive immunological reaction against the tumour. Although examples and explanations are found in the standard manual, here, the special importance of identifying and managing cytokine release syndrome (CRS) should be emphasized, and the standards focus not on specific therapeutic algorithms but on ensuring that medical and nursing teams are sufficiently trained in the early detection of this and other potential complications (e.g., neurological complications). They also pay attention to the full-time availability within the institution and its pharmacy of the necessary medication to address complications and the capacitation and involvement of Intensive Care and Neurology Department professionals to provide urgent care if needed. Forthcoming cellular therapy products, currently under investigation, will show a wider range of risk profiles, therefore requiring product-specific risk assessment and consequent adaptation of the clinical procedures for different classes of products. The FACT-JACIE standards will continue to adapt to these future needs to assist centres in their achievement of optimal clinical outcomes.
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LEAL, A. G., and J. L. NOVAK FILHO. "LIGA ACADÊMICA DE NEUROLOGIA E NEUROCIRURGIA DO INSTITUTO DE NEUROLOGIA DE CURITIBA (INC)." In NEURO FUNDAMENTAL, 15–16. EDITORA CRV, 2019. http://dx.doi.org/10.24824/978854443952.4.15-16.

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Orozco, Fabio, and T. Tarity. "Management of Neurologic Deficit: Hip." In Rothman Institute Manual of Total Joint Arthroplasty: Protocol-Based Care, 627. Jaypee Brothers Medical Publishers (P) Ltd., 2017. http://dx.doi.org/10.5005/jp/books/13027_103.

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Orozco, Fabio, and T. Tarity. "Management of Neurologic Deficit: Knee." In Rothman Institute Manual of Total Joint Arthroplasty: Protocol-Based Care, 633. Jaypee Brothers Medical Publishers (P) Ltd., 2017. http://dx.doi.org/10.5005/jp/books/13027_104.

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Conference papers on the topic "Instituto de neurología"

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Silva, Eluan Joel Rodrigues da, Cristiano de Bem Torquato de Souza, Raphael Henrique Chappuis, Sarah Evelyn Silva Fernandes, and Kleber Fernando Pereira. "Scientific production on the effects of COVID-19 on the central nervous system: a systematic review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.493.

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Background: The presence of COVID-19 in the world has brought changes to our society. The research groups around the world started an analysis of how the SARS-CoV-2 virus interacts pathophysiologically with biological systems. Objectives: Quantify, based on the literature, the scientific production by Institution and country of origin, which related the damage of COVID-19 in the Central Nervous System (CNS). Design and setting: We conducted a literature review. It was use the databases of PubMed, LILACS (Latin American and Caribbean Literature on Health Sciences), SciElo and The Lancet. Results: 91 articles were included. The Institutions with the most publications were: University of California (United States), All India Institute Of Medical Sciences (India) and Qingdao University (China), with May 2020 being the period with the most publications. The most frequent symptoms caused by COVID-19 in the CNS were: Anosmia, Headache, Vomiting, Nausea and Hyposmia. Conclusions: United States, India and China were the countries with an expressive, even small, number of publications relating the effects of COVID-19 on the CNS. The largest number of publications in May 2020 shows that studies were rapidly developed shortly after the disease was raised to the level of a pandemic in March of the same year. The symptomatic effects of the disease show the primary involvement of the respiratory system with effects on the CNS.
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Celis-López, Miguel A. "Dedicated Linac for Radioneurosurgery at the National Institute of Neurology and Neurosurgery of Mexico." In MEDICAL PHYSICS: Seventh Mexican Symposium on Medical Physics. AIP, 2003. http://dx.doi.org/10.1063/1.1615097.

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Alva-Sánchez, Héctor, Alberto Reynoso-Mejía, Katiuzka Casares-Cruz, and Jesús Taboada-Barajas. "Patient dose estimation from CT scans at the Mexican National Neurology and Neurosurgery Institute." In XIII MEXICAN SYMPOSIUM ON MEDICAL PHYSICS. AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4901369.

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Brooks, Joseph Bruno Bidin. "De novo variant in the MAPK8IP3 gene in the differential diagnosis of global development delay. Case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.181.

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Context: The global development delay has a high prevalence and heterogeneity in the world population. With the advancement of technology and detection of pathogenic variants detected by sequencing the exome, genes related to global developmental delay could be identified and collaborate for further clinical clarification. Among the studied genes, the MAPK8IP3 gene, became an attractive candidate due to its performance in neuronal axonal transport in vertebrates and invertebrates. This case report was approved by the Ethics Committee of Universidade Metropolitana de Santos. Case Report: The present case refers to a 6-year-old male patient presenting with a clinical picture of global developmental delay without bodily dysmorphia. Cerebellar ataxia, muscle hypotonia and intellectual impairment are important clinical impairments. Skull MRI and complementary exams were normal. The genetic study showed a new and heterozygous pathogenic variant in the MAPK8IP3 gene. Conclusions: Symptomatic treatment with multiprofessional rehabilitation was instituted with partial improvement of symptoms.
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Seraidarian, Marina Buldrini Filogônio, Daniel Vasconcelos de Pinho Tavares, Tassila Oliveira Nery de Freitas, Paolla Giovanna Rossito de Magalhães, Gabriella Braga da Cunha Silva, Barbara Oliveira Paixao, Maíra Cardoso Aspahan, and Rodrigo Santiago Gomez. "Diethylene glycol poisoning: report of two cases due to brewery contamination." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.174.

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Context: Diethylene glycol (DEG) is an alcohol used as industrial antifreeze. Poisoning is usually accidental and involves contamination of food and beverage. We report two cases of DEG poisoning (DEGP) resulting from ingestion of beer in 2020. Case report: ACMO, male, 57 year-old, admitted with bilateral visual turbidity complaint. Laboratory showed renal dysfunction (Cr 11 mg/dl, Ur 202 mg/dl), increased anion GAP (AG) and metabolic acidosis. He evolved with amaurosis, facial diplegia, tetraparesis and areflexia. He was discharged after prolonged hospitalization with severe motor impairment, bilateral amaurosis and under dialysis therapy. RJB, 75 year-old alcoholic male patient, reported 600 ml/day ingestion of high-risk beer in the month preceding his hospitalization. He was admitted with nausea, abdominal pain, renal failure (Cr 11 mg/dl, Ur 177 mg/dl), metabolic acidosis and AG 21. He developed bilateral papilla edema, flaccid tetraparesis, areflexia, dysautonomy, respiratory failure and death. Conclusions: DEG metabolites primarily target kidneys and nervous system. Patients shortly develop nephroneural syndrome characterized by acute oligoanuric renal injury with metabolic acidosis and increased AG, associated with peripheral polyneuropathy with involvement of cranial nerves, in addition to optic neuropathy. Due to the poorly available serum dosage, rapid recognition of DEGP is essential to institute early treatment and identification of the source of the intoxication in order to prevent mass poisoning.
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Lemos, Gabrielle Torres Oliveira, Gabriel das Chagas Benevenuto, Gabriela Guy Duarte, Bruno Alves Pinto, and Ivan Magalhães Viana. "The use of Botulinum toxin type A for the treatment of refractory chronic migraine." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.566.

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Background: Chronic migraine is a neurological disorder described as refractory to preventive treatments. Based on the PREEMPT study, the National Institute for Health and Clinical Excellence (NICE) and the FDA approved, in 2010, the use of Botulinum Toxin type A (BoNT/A) to treat refractory chronic migraine. Objectives: To review the effectiveness of the use of BoNT/A in the treatment of refractory migraine. Methods: Bibliographic review based on PubMed database, using the descriptors “migraine” and “botulinum toxin”. Clinical trials, meta-analyzes and randomized controlled tests, from the last five years, were defined as inclusion criteria. Results: Sanz et al., (2016) infiltrated BoNT/A in 69 patients - mean age 43 years old, 88.4% women, mean infiltration rate was 2,0. The reduction of headache days and pain intensity was 48.5% and 20.5%, respectively, both statistically significant (p <0.006). Ion et al., (2018) intervened 61 patients - mean age 50 years old, 87% women, mean infiltration of 3.5. 73% showed a reduction greater than 50% for the frequency of migraine episodes, 48% for headache days and 48% for drug use. Dodick et al., (2019) applied BoNT/A in 688 patients - 696 received placebo. The severity and frequency of pain showed a statistically significant reduction (p < 0.001) after the first week of treatment in relation to the control group. Conclusions: The use of BoNT/A to treat refractory chronic migraine proves to be effective, although there is need for studies with larger samples to ensure its effectiveness.
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Moraes, Marianna, Fabiano Abrantes, José Luiz Pedroso, and Orlando Graziani Povoas Barsottini. "Etiological evaluation of hypertrophic pachymeningitis in a tertiary general neurology department." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.665.

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Introduction: Hypertrophic pachymeningitis (HP) is the thickening of the cranial or spinal dura. This process causes cranial nerve palsy, vascular events (stroke and venous thrombosis), and intracranial hypertension. The diagnosis of HP is disclosed by magnetic resonance imaging, showing dural thickening and contrast enhancement. Several etiologies are possible for HP, but infection and autoimmune diseases are the most frequent. The gold standard for diagnosis is the dural biopsy, but cerebrospinal fluid (CSF), blood and other tissues analysis are essential guides to the correct diagnosis. A quick diagnosis is crucial to early treatment and this avoid permanent deficits. However, the diagnostic approach can be a complicated process, which could delay the beginning of the treatment. Objectives: This study aims to analyze the population of patients with magnetic resonance imaging showing HP. Methods: Its epidemiological, clinical and radiological aspects was evaluated through a retrospective and descriptive study to elucidate the etiological diagnosis. Results: A total of 45 patients was included with some different etiologies: granulomatosis with polyangiitis (n = 7); idiopathic (n = 14); probable neurosarcoidosis (n = 9); seronegative rheumatoid arthritis (n = 1); neurotuberculosis (n = 1); plaque meningioma (n = 2); IgG4 related disease (n = 4); Inflammatory myofibloblastic tumor (n = 1); neurosyphilis (n = 1); diffuse B-cell lymphoma (n = 1); Erdheim-Chester disease (n = 1); iatrogenic secondary to radiotherapy (n = 1) and cryopyronopathy (n = 1). Conclusion: The diversity of etiologies found in this study demonstrates the complexity of HP and how important it is to follow a diagnostic algorithm in order to institute appropriate and early therapy for a better clinical outcome for patients.
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Paiva, João Paulo Silva de, Jussara Almeida de Oliveira Baggio, Thiago Cavalcanti Leal, Leonardo Feitosa da Silva, Lucas Gomes Santos, Rodrigo Feliciano do Carmo, Gibson Barros de Almeida Santana, et al. "Epidemiology of Cerebrovascular Disease Mortality in Brazil (1996- 2015): temporal modeling using inflection point regression." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.094.

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Background: cerebrovascular diseases (CVD) are the second leading cause of death in the world. Objective: to analyze the trend of mortality from CVD in Brazil (1996-2015) and its association with the human development index (HDI) and the social vulnerability index (IVS). Methods: this is an ecological study involving mortality rates standardized by CVDD. Death data were obtained from the Mortality Information System and population data from the Brazilian Institute of Geography and Statistics. For temporal analyzes, the inflection point regression model was used, with the annual percentage change (APC) and average annual percent change (AAPC), with a confidence interval of 95% and significance of 5%. The trends were classified as increasing, decreasing or stationary. The multivariate regression model was used to test the association between mortality from CVD, HDI and IVS. Results: 1,850,811 deaths due to CVD were recorded in the studied period. There was a reduction in the national mortality rate (APC:-2.4; p=0.001). Twenty federative units showed significant trends, 13 of which were decreasing, including all from the Midwest (n=4), Southeast (n=4) and South (n=3) regions. The HDI had a positive association and the IVS, a negative association with mortality (p=0.046 and p=0.026, respectively). Conclusion: the study showed an unequal epidemiological behavior of mortality among the regions, being higher in the states of the Southeast and South, but with a significant tendency to decrease, and lower in the states of the North and Northeast, but with a significant trend of growth. HDI and IVS were associated with mortality.
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Zocche Junior, Giovani, Isadora Ghilardi, Laura Provenzi, Gabriel Leal, Giulia Pinzetta, Nicole Becker, Vitoria Pimentel, et al. "Modulation of gene transcription promoted by mesenchymal stem cells on cation-chloride cotransporter NKCC1 in experimental epilepsy." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.684.

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Introduction: temporal lobe epilepsy is a disorder in which synchronized and rhythmic neural firing causes spontaneous recurrent seizures (1). Refractoriness due to this condition reaches 30% of its carriers (2,3). The search for therapeutic alternatives to help cope with this disease are extremely important. Mesenchymal stem cells (MSCs) appear as a plausible treatment option, as they present a less invasive approach and due to their niche modulating character (4,5). Objectives: this study aimed to quantify the gene expression of cation-chloride cotransporter NKCC1 encoded by the SLC12A2 gene in the encephalic tissue of pilocarpine-induced epileptic rats (6,7). Design: experimental study, brain institute of Rio Grande do Sul. Methods: MSCs were obtained from the bone marrow of Wistar rats, cultured, and transplanted through intravenous injection into control and epileptic Wistar rats. The rats were divided between control group, MSCs treated group, and pilocarpine group, containing 8 individuals each (8). Expression analysis was performed using real-time polymerase chain reaction. Results: for both 1 day and 7 days post-transplantation, an increase in the NKCC1 expression in both control and epileptic treated groups as compared to its expression in untreated epileptic and control groups with special attention to the amygdala, the hippocampus and the prefrontal cortex. Conclusion: MSCs stimulated expression of NKCC1 in brain structures of rats induced by pilocarpine to epilepsy. This corroborates the hypothesis of neuroprotective effects and modulating properties of stem cells and may point to more mechanisms for investigating the functioning and collaboration of these cells as a treatment for epilepsy.
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Disserol, Caio, João Henrique Fregadolli Ferreira, Carolina Magalhães Britto, Maria Clara Spesotto, Carla Guariglia, and Marcos Christiano Lange. "Progressive lacunar stroke presenting as cheiro-oral syndrome, dysarthria and hemiataxia." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.636.

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Context: Lacunar infarcts are small infarcts caused by occlusion of a single penetrating vessel, affecting mostly the basal ganglia, subcortical white matter and pons1. Around 20-30% of patients may progress symptoms over hours to days, and this presentation is associated with disability and poor prognosis2. Case report: A 70-year-old man with history of smoking, hypertension and a previous right occipital stroke reported right upper lip paresthesias since awakening. In 2-hours the right perioral region and his right hand were affected. After 3-hours he noted slurred speech. After 4-hours, imbalance was added to the previous symptoms. On admission, NIHSS was 4, mostly by previous left hemianopia, new right arm ataxia and cerebellar dysarthria. There were no weakness or sensory déficits. Brain MRI showed a subacute lacunar stroke in the left thalamus. Discussion: Thalamic lacunar strokes can present in a wide range of symptoms depending on the affected nuclei. The ventral posterior lateral nucleus (VPLn) and the ventral posterior medial nucleus (VPMn) carries sensory input from the contralateral body and face, respectively3. Cheiro-oral syndrome (COS) is considered a pure sensory thalamic lacunar syndrome with symptoms that affect the face, hand and/or foot, but may be accompanied by ipsilateral ataxia if the ventral lateral nucleus is also affected4 . Although classically associated with thalamic ischemic lesions, there are descriptions of hemorrhagic strokes5 and multiple different affected regions presenting as COS, including brainstem5 , internal capsule6 , operculum7 , cortex8 , corona radiata9 and thalamus10. Early recognition and diagnosis is essencial to institute adequate early treatment and secondary prophylaxis.
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