Relevant bibliographies by topics / Insulin

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Insulin'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Insulin"

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Hansenne, Isabelle Sylvie, Chantal Renard, and Vincent Geenen. "Igf2 expression is required for complete tolerance to insulin (128.19)." Journal of Immunology 178, no. 1_Supplement (2007): S213—S214. http://dx.doi.org/10.4049/jimmunol.178.supp.128.19.

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Abstract All members of insulin gene family are transcribed in human thymus according a hierarchy whereby IGF2 expression (thymic epithelial cells/TEC) exceeds IGF1 (macrophages), which exceeds INS (medullary TEC). Type 1 and type 2 IGF receptors are expressed by thymic T-cell populations. To further study the expression of IGF-2 in thymus, the dominance of this factor was compared to insulin, while ontogenesis of Igf2, insulin1 and insulin2 transcription was studied in Balb/c pancreas and thymus. In 4-wk old thymi, IGF-2 concentration is higher than insulin content. Ontogenesis of Igf2, insul
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Shestakova, Marina Vladimirovna, and Irina Vladimirovna Glinkina. "Insulin glargine does not increase the risk of malignancy.Synopsis of the article ?Combined randomised controlled trial experience of malignancies in studies using insulin glargine?byHome P.D. & Lagarenne P. (Diabetologia 2009, vol. 52 (12): 2499-2506)." Diabetes mellitus 13, no. 1 (2010): 88–90. http://dx.doi.org/10.14341/2072-0351-6022.

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Results of 31 controlled randomized studies of insulin glargine given to patients with diabetes mellitus are reviewed to evaluate the frequency of malignantneoplasms. 52 tumours were diagnosed in 45 (0.8%) patients on insulin glargine therapy and 48 tumors in 46 (0.9%) patients using other insulins(mostly NPX insulin). The incidence of breast cancer was equal (0.1%) in both groups (4 and 6 cases respectively). These data indicate thatthe use of insuline glargine does not increase the risk of malignancy, e.g. breast cancer.
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Dąbrowski, Mariusz. "U kogo i dlaczego warto zastosować insulinę dwuanalogową aspart + degludec?" Medycyna Faktów 16, no. 2(59) (2023): 227–33. http://dx.doi.org/10.24292/01.mf.0223.15.

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Ostatnie lata przyniosły istotne zmiany paradygmatu terapii cukrzycy typu 2. Po ogłoszeniu wyników pierwszych i kolejnych badań bezpieczeństwa sercowo-naczyniowego leków przeciwcukrzycowych na pierwszą linię frontu wysunęły się leki nieinsulinowe, a szczególne miejsce zajęły inhibitory kotransportera sodowo-glukozowego typu 2 i agoniści receptora glukagonopodobnego peptydu-1 (te drugie są rekomendowane jako pierwsza terapia iniekcyjna w cukrzycy typu 2). Spowodowało to nieznaczny spadek liczby pacjentów leczonych insuliną. Niemniej należy pamiętać, że w populacji osób z cukrzycą typu 2 u wielu
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Modi, K. D., Pradeep V. Gadge, Pradeep Jain, et al. "Clinical challenges with excipients in insulin formulations and role of concentrated insulin." International Journal of Basic & Clinical Pharmacology 8, no. 4 (2019): 821. http://dx.doi.org/10.18203/2319-2003.ijbcp20191125.

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Most of the insulin formulations in clinical use contain phenol, meta-cresol or both as excipients. These excipients in insulin preparations provide stability and have antimicrobial properties. However, they are reported to be associated with undesirable side-effects especially localised allergic reactions. Amount of excipients injected per unit dose of insulin is a major determining factor in causation of these reactions. This review discusses the excipients in different insulin formulations available in India with potential of precipitating undesirable effects and the use of concentrated ins
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Kucera, Michelle L., and John P. Graham. "Insulin Lispro, a New Insulin Analog." Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 18, no. 3 (1998): 526–38. http://dx.doi.org/10.1002/j.1875-9114.1998.tb03116.x.

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Insulin lispro is a rapid‐acting insulin analog to regular insulin. Inversion of the proline‐lysine amino acid sequence at positions 28 and 29 on the B chain is responsible for its more rapid absorption, faster onset, and shorter duration of action compared with regular insulin. The fast onset of action allows for greater flexibility in dosing and mealtime scheduling. Insulin lispro provides equivalent or slightly improved glycemic control in patients with types I and II diabetes mellitus compared with regular insulin, without subsequent increases in hypoglycemic episodes. It also results in g
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Ray, Sumit. "Insulin infusion protocol (Human insulin®/Insugen®)." Current Medicine Research and Practice 4, no. 4 (2014): 186–87. http://dx.doi.org/10.1016/j.cmrp.2014.08.007.

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Gargiulo, P., U. Di Mario, O. Zuccarini, et al. "Treatment of diabetic pregnant women with monocomponent insulins." Acta Endocrinologica 113, no. 3_Suppl (1986): S60—S65. http://dx.doi.org/10.1530/acta.0.111s0060.

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Abstract. Very little immunological research has been undertaken in pregnant diabetic women in relation to insulin therapy. We investigated the relations between treatment with insulins of varied immunogenic character and the presence of immune factors such as insulin antibodies, immune complexes and insulin antiinsulin complexes as well as some maternal and neonatal complications of diabetic pregnancy. 128 insulin treated diabetic pregnant women and 121 of their newborns were included in the study. The incidence of insulin antibodies, immune complexes and insulin antiinsulin complexes was low
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Mbanya, Jean Claude, Juergen Sandow, Wolfgang Landgraf, and David R. Owens. "Recombinant Human Insulin in Global Diabetes Management – Focus on Clinical Efficacy." European Endocrinology 13, no. 01 (2017): 21. http://dx.doi.org/10.17925/ee.2017.13.01.21.

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Biosynthetic human insulin and insulin analogues are the mainstay of insulin therapy for both type 1 and type 2 diabetes although access to human insulin at affordable prices remains a global issue. The world is experiencing an exponential rise in the prevalence of diabetes presenting an urgent need to establish effective diabetes therapy in countries burdened by inadequate health care budgets, malnutrition and infectious diseases. Recombinant human insulin has replaced animal insulins and animal-based semisynthetic human insulin thereby available in sufficient quantities and at affordable pri
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Ahmed Aziz, Kamran Mahmood. "Role of New Insulin Analogs in the Management of Diabetes. A Clinical Review." Diabetes & Obesity International Journal 8, no. 1 (2023): 1–8. http://dx.doi.org/10.23880/doij-16000269.

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This paper has reviewed different insulin analogs currently available in the market and pharma industry, their safety, efficacy and their roles in the diabetes management, comparing with human regular and NPH insulin. Traditional insulins (human regular and NPH insulins) do not have constant or smoother pharmacokinetic and pharmacodynamic profiles and are usually associated with erratic blood glucose profiles with hypoglycemia or hyperglycemia when compared with analog insulins. Similarly they do not match physiologic insulin profiles with basal bolus format. According to the medical literatur
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Hirsch, Irl B., Rattan Juneja, John M. Beals, Caryl J. Antalis, and Eugene E. Wright. "The Evolution of Insulin and How it Informs Therapy and Treatment Choices." Endocrine Reviews 41, no. 5 (2020): 733–55. http://dx.doi.org/10.1210/endrev/bnaa015.

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Abstract Insulin has been available for the treatment of diabetes for almost a century, and the variety of insulin choices today represents many years of discovery and innovation. Insulin has gone from poorly defined extracts of animal pancreata to pure and precisely controlled formulations that can be prescribed and administered with high accuracy and predictability of action. Modifications of the insulin formulation and of the insulin molecule itself have made it possible to approximate the natural endogenous insulin response. Insulin and insulin formulations had to be designed to produce ei
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Dissertations / Theses on the topic "Insulin"

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Guarilha, Alessandra Lia Gasparetti. "Transdução do sinal da insulina em animais expostos ao frio : o papel do cross-talk entre o receptor 'beta' 3 - adrenergico e o receptor de insulina em tecido adiposo marrom." [s.n.], 2004. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310365.

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Orientador: Licio Augusto Velloso<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-04T02:29:02Z (GMT). No. of bitstreams: 1 Guarilha_AlessandraLiaGasparetti_D.pdf: 7883483 bytes, checksum: cefd0ee77fd363b470280f9b8a380ff9 (MD5) Previous issue date: 2004<br>Resumo: A exposição de animais homeotérmicos ao mo é utilizada como um método reprodutível para se obter um modelo animal de hipoinsulinemiaacompanhada por elevada mobilização periférica de glicose. No presente estudo, avaliaram-se as etapas iniciais e intermediár
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Aili, Fagerholm Siri. "Insulin signaling in primary adipocytes in insulin sensitive and insulin resistant states." Doctoral thesis, Linköpings universitet, Avdelningen för cellbiologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-95562.

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Increasing numbers of people world-wide develops the disease type 2 diabetes. Development of type 2 diabetes is characterized by a shift from an insulin sensitive state to an insulin resistant state in peripheral insulin responding organs, which originates from the development of insulin resistance in the adipose tissue. Insulin resistance in combination with reduced pancreatic insulin secretion lead to overt type 2 diabetes. In this thesis, the insulin signaling network in primary adipocytes was analyzed. Key proteins and mechanisms were studied to gain deeper knowledge of signaling both in t
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Protzek, André Otavio Peres 1984. "Increased insulin secretion and decreased insulin clearance contributes to the hyperinsulinemia in rats and mice treated with glucocorticoid = Aumento da secreção e redução do clearance de insulina contribuem para a hiperinsulinemia compensatória em ratos e camundongos tratados com glicocorticoide." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313949.

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Orientadores: Antonio Carlos Boschiero, Alex Rafacho<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-24T03:03:43Z (GMT). No. of bitstreams: 1 Protzek_AndreOtavioPeres_D.pdf: 8312725 bytes, checksum: 2126056342598338000e5d9925e59082 (MD5) Previous issue date: 2013<br>Resumo: Os glicocorticoides (GC) são amplamente utilizados devido aos seus efeitos anti-inflamatórios. Porém, o tratamento com GC pode induzir efeitos deletérios sobre a homeostase glicêmica como a resistência à insulina (RI), intolerância à glicose e, dependen
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Tavare, J. M. "The insulin receptor and insulin stimulated protein kinase : Their role in insulin action." Thesis, University of Bristol, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370675.

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Moraes, Keila Aziz Chehoud de [UNESP]. "Efeitos decorrentes da ingestão do fluoreto na sensibilidade à insulina e transdução do sinal insulínico." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/95423.

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Made available in DSpace on 2014-06-11T19:27:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-03-08Bitstream added on 2014-06-13T19:56:34Z : No. of bitstreams: 1 moraes_kac_me_araca.pdf: 306630 bytes, checksum: d5a66918144c7975dabc631c6c9b84ec (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Nos últimos anos tem ocorrido uma redução acentuada nos índices de cárie dentária em diversas regiões do planeta, fato que tem se atribuído ao consumo de produtos fluoretados. Entretanto, o flúor, quando ingerido em excesso, causa intoxicação crônica ou aguda, como a flu
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Bertelli, Daniela Faleiros. "Mecanismos moleculares envolvidos no controle da ingestão alimentar e do peso corporal : participação da 5PTASE IV." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312921.

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Orientador: Licio Augusto Velloso<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-07T04:07:10Z (GMT). No. of bitstreams: 1 Bertelli_DanielaFaleiros_D.pdf: 2445017 bytes, checksum: 2a78cdd0f1bc8fc197cb47c83deb0c0b (MD5) Previous issue date: 2006<br>Resumo: A enzima fosfatidilinositol 3-quinase (PI3-kinase) exerce uma importante função na transdução dos sinais anorexigênicos e termogênicos enviados pela insulina e leptina em primeira ordem aos neurônios do núcleo arqueado no hipotálamo. A cascata de sinais intracelul
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Hagihara, Graziela Neves. "Resposta à angiotensina II em artérias mesentéricas de resistência na obesidade: participação das MAPKs." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/42/42136/tde-18092012-095317/.

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A angiotensina II (AngII) pode ativar as vias de sinalização das proteínas quinases ativadas por mitógenos (MAPKs). Investigamos o papel da obesidade e das MAPKs na resposta à AngII em ratos obesos por injeção de glutamato monossódico (Ob). Artérias mesentéricas de resistência com endotélio intacto e não as artérias sem endotélio, isoladas de Ob, respondem menos à AngII. As respostas à noradrenalina e ao cloreto de potássio estavam inalteradas. Aumento da expressão do receptor AT2 (AT2R), da óxido nítrico sintase (eNOS) e da ERK1/2 podem estar envolvidos na menor resposta pois a inibição do A
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Pacheco, Calderón Javier, Fernández Paloma Salas, and Rigo-Righi Carla Galli. "Vanadium Insulin mimetic activity." Revista de Química, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/100049.

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La diabetes mellitus es un serio desorden metabólicocrónico que se caracteriza por el incremento anormal de laglucosa en la sangre y por complicaciones vasculares yneurológicas. La diabetes mellitus es causada por una falta oun defecto en la acción de la insulina. Si bien actualmenteexisten varios medicamentos orales además de la insulina oanálogos de la insulina, ninguno de estos es el ideal.El vanadio es capaz de imitar los efectos mostrados por lainsulina tanto in vitro como in vivo y se estudia la posibilidadde usar compuestos de vanadio como agentes antidiabéticos. Eneste artículo se revi
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Capetini, Vinícius Cooper. "Efeito da suplementação com zinco na evolução da resistência à insulina induzida por dieta hiperlipídica em camundongos." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/42/42137/tde-10082016-154401/.

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O aumento da prevalência do diabete melito do tipo 2 (DM2) é intenso e implica ampla busca pela prevenção e tratamento da doença. Estudos têm mostrado a participação do zinco na síntese, secreção e via de sinalização da insulina e sobre o controle glicêmico. Este trabalho objetivou analisar o mecanismo de ação do zinco no controle da secreção de insulina e no controle glicêmico, de modo a entender se a suplementação com o zinco previne ou retarda a manifestação do DM2. O projeto foi aprovado pela CEUA-ICB (USP). Camundongos machos C57BL/6 foram divididos em 4 grupos experimentais: dieta contr
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Gormley, M. J. J. "Aspects of insulin treatment of non-insulin-dependent diabetes." Thesis, Queen's University Belfast, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373006.

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Books on the topic "Insulin"

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Cuatrecasas, Pedro, and Steven Jacobs, eds. Insulin. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74098-5.

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Brian, Kahn. Insulin. Cambridge Micro Software, 1987.

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United States. Food and Drug Administration. Office of Women's Health. Insulin. Dept. of Health and Human Services, FDA, Office of Women's Health, 2010.

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Pedro, Cuatrecasas, Jacobs Steven 1946-, and Avruch J, eds. Insulin. Springer-Verlag, 1990.

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Eleazar, Shafrir, and Hansen Barbara C, eds. Insulin resistance and insulin resistance syndrome. Taylor & Francis, 2002.

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Zeitler, Philip S., and Kristen J. Nadeau, eds. Insulin Resistance. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-25057-7.

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Srivastava, Ashok K., and Barry I. Posner, eds. Insulin Action. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5647-3.

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Reaven, Gerald M., and Ami Laws, eds. Insulin Resistance. Humana Press, 1999. http://dx.doi.org/10.1007/978-1-59259-716-1.

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Strachan, Mark W. J., and Brian M. Frier. Insulin Therapy. Springer London, 2013. http://dx.doi.org/10.1007/978-1-4471-4760-2.

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Zeitler, Philip Scott, and Kristen J. Nadeau, eds. Insulin Resistance. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-192-5.

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Book chapters on the topic "Insulin"

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Titchener, Janet. "Insulins and insulin management." In Diabetes Management. CRC Press, 2020. http://dx.doi.org/10.1201/9780429326196-6.

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Titchener, Janet. "Insulins and insulin management." In Diabetes Management. CRC Press, 2020. http://dx.doi.org/10.4324/9780429326196-6.

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Brandenburg, D. "Insulin Chemistry." In Insulin. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74098-5_1.

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Hollenberg, M. D. "Insulin Receptor-Mediated Transmembrane Signalling." In Insulin. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74098-5_10.

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Rothenberg, P., M. F. White, and C. R. Kahn. "The Insulin Receptor Tyrosine Kinase." In Insulin. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74098-5_11.

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Levy, J. R., and J. M. Olefsky. "Receptor-Mediated Internalization and Turnover." In Insulin. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74098-5_12.

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Jacobs, S. "Insulin-like Growth Factor I Receptors." In Insulin. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74098-5_13.

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Saltiel, A. R., and P. Cuatrecasas. "Second Messengers of Insulin Action." In Insulin. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74098-5_14.

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Avruch, J., H. E. Tornqvist, J. R. Gunsalus, E. J. Yurkow, J. M. Kyriakis, and D. J. Price. "Insulin Regulation of Protein Phosphorylation." In Insulin. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74098-5_15.

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Larner, J. "Effects of Insulin on Glycogen Metabolism." In Insulin. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74098-5_16.

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Conference papers on the topic "Insulin"

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Perez, Daniel L., and Ivo Braganza. "Reimagining the Insulin Pump User Experience." In 2024 IEEE Integrated STEM Education Conference (ISEC). IEEE, 2024. http://dx.doi.org/10.1109/isec61299.2024.10664701.

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Aljawawdeh, Hamzeh, Rajae Dughmosh, Dema Almashaqbeh, Heba Alazzeh, and Ayoub Aldroubi. "Smart Insulin Calculator: Technological Innovation for Type 1 Diabetes Management Revolutionising Insulin Management with Intelligent Health Technology." In 2024 Global Digital Health Knowledge Exchange & Empowerment Conference (gDigiHealth.KEE). IEEE, 2024. http://dx.doi.org/10.1109/gdigihealth.kee62309.2024.10761341.

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V, Manimekalai, Varshika K, Nalen G J, and Sri Sharen C K. "Smart Insulin Patch With AI Optimized Delivery." In 2025 3rd International Conference on Advancements in Electrical, Electronics, Communication, Computing and Automation (ICAECA). IEEE, 2025. https://doi.org/10.1109/icaeca63854.2025.11012222.

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Rosa, PS, CMAF Ferrer, and GA Delfino. "ESTUDO DE PREVALÊNCIA DE MACROINSULINA UTILIZANDO DOSAGEM DE INSULINA LIVRE." In Resumos do 54º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2022. http://dx.doi.org/10.5327/1516-3180.140s1.7179.

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Objetivo: Estudar a prevalência de macroinsulina em amostras ambulatoriais cujo resultado de insulina total foi superior a 200 mU/l, realizando a dosagem de insulina livre. Método: As dosagens de insulina foram realizadas com um imunoensaio de eletroquimioluminescência (Roche Elecsys 2010, Roche Diagnostics, kit: Insulin). Cinquenta amostras foram selecionadas para validação da dosagem de insulina livre. A insulina livre foi determinada por meio da dosagem de insulina no sobrenadante da amostra após precipitação com polietilenoglicol 25%. Todas as amostras da rotina laboratorial ambulatorial d
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Goodwin, P. "Obesity, Insulin Resistance and Insulin." In Abstracts: Thirty-Second Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 10‐13, 2009; San Antonio, TX. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-09-ms2-1.

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Lin, J., P. Docherty, A. Le Compte, et al. "Modeled Insulin Sensitivity and Interstitial Insulin Action from a Pilot Study of Dynamic Insulin Sensitivity Tests." In UKACC International Conference on CONTROL 2010. Institution of Engineering and Technology, 2010. http://dx.doi.org/10.1049/ic.2010.0358.

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Jayaraj, Nivethitha, C. Mathew Cherian, and S. Ganesh Vaidyanathan. "Intelligent Insulin Infuser." In 2009 Third UKSim European Symposium on Computer Modeling and Simulation. IEEE, 2009. http://dx.doi.org/10.1109/ems.2009.64.

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Vereshchetin, Paul, Marc Breton, and Stephen D. Patek. "Mealtime correction insulin advisor for CGM-informed insulin pen therapy." In 2013 American Control Conference (ACC). IEEE, 2013. http://dx.doi.org/10.1109/acc.2013.6580277.

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Cesar, Palerm,. "Physiologic Insulin Delivery with Insulin Feedback: A Control Systems Perspective." In Modeling and Control in Biomedical Systems, edited by Rees, Stephen, chair Andreassen, Steen and Andreassen, Steen. Elsevier, 2009. http://dx.doi.org/10.3182/20090812-3-dk-2006.00006.

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Baura, Gail D., David M. Foster, and Michael W. Schwartz. "Insulin receptors facilitate insulin transport into the central nervous system." In 1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1992. http://dx.doi.org/10.1109/iembs.1992.5761454.

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Reports on the topic "Insulin"

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Anthony Di Franco, Anthony Di Franco. Open Insulin. Experiment, 2015. http://dx.doi.org/10.18258/5755.

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Nardelli, Natalia. ATTD 2025: Science and Technology. Edited by María Fernanda Cristoforetti. Lugones Editorial, 2025. https://doi.org/10.47196/0593.

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Muti, Paola. Insulin and Breast Cancer Risk. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada395852.

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Muti, Paola. Insulin and Breast Cancer Risk. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada383382.

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Yibchok-anun, Sirintorn, Sophon Roengsumran, and H. Hsu, Walter. Protein extract from fruit pulp of Siamese momordica charantia with insulin secretagogue and insulin-like activities. Chulalongkorn University, 2004. https://doi.org/10.58837/chula.res.2004.84.

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The aim of this study was to investigate the effects of zinc-free protein extract from bitter gourd fruit pulp on plasma glucose concentration and insulin responses in normal and STZ-induced diabetic rats. Furthermore, we investigated the direct effect of the MC protein extract on insulin and glucagons secretions from the perfused rat pancreas as well as glucose uptake in C2C12 rat myocytes and 3T3-L1 rat adipocytes. The protein from Thai bitter gourd (Momordica charantia) fruit pulp was extracted and studied for its hypoglycemic effect. Subcutaneous administration of the protein extract (5 an
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Silva, Rodrigo Ribeiro e., Mateus de Miranda Gauza, Julia Opolski Nunes da Silva Opolski, and Maria Eduarda Schramm Guisso. Once-Weekly Insulin Icodec vs Once-Daily Insulin Glargine U100 for Type 2 Diabetes: A Meta-analysis of Phase 2 Randomized Controlled Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.5.0102.

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Review question / Objective: To compare Once-Weekly Insulin Icodec and Once-Daily Insulin Glargine U100 in patients with Type 2 Diabetes Mellitus using oral hypoglycemic drugs in need of insulin therapy. Condition being studied: Patients with Diabetes Mellitus Type 2 using oral hypoglycemic drugs in need for basal insulin. Eligibility criteria: Inclusion in this meta-analysis was restricted to studies that met all the following criteria: (1) randomized trials; (2) comparing the use once weekly insulin icodec to once daily insulin glargine; (3) enrolling patients with type 1 or type 2 diabetes
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Long, Cong, XUke Han, Yunjiao Yang, Tongyi Li, Qian Zhou, and Qiu Chen. Efficacy of Intranasal Insulin in Improving Cognition in Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.8.0054.

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Review question / Objective: How does the efficacy of Intranasal Insulin in improving Cognition in Mild Cognitive Impairment or Dementia. Condition being studied: Insulin regulates many aspects of brain function related to mild cognitive impairment (MCI) or dementia, which can be delivered to the brain center via intranasal (IN) devices. Some small, single-site studies indicated that intranasal insulin can enhance memory in patients with MCI or dementia. The pathophysiology of Alzheimer disease (AD) and diabetes mellitus (DM) overlap, making insulin an attractive therapy for people suffering f
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Nadeau, Jenifer. Insulin Resistance in Horses - Does it Matter? UConn Extension, 2025. https://doi.org/10.61899/ucext.v2.101.2025.

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ZHU, Dongshan. The lifestyle changes after initiating basal insulin in insulin naive patients with type 2 diabetes: Results from the ORBIT study. Science Repository, 2019. http://dx.doi.org/10.31487/j.jicoa.2019.02.04.

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Shi, Jinping, Feng L, Liting X, Jing L, and Xing L. Meta analysis of efficacy and safety of insulin aspart and biosynthetic human insulin in the treatment of gestational diabetes mellitus. Xi'an International Medical Center Hospital, 2021. http://dx.doi.org/10.37766/inplasy2021.7.0047.

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