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Journal articles on the topic 'Insulin-like growth factor-binding proteins'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Kostecká, Z., and J. Blahovec. "Animal insulin-like growth factor binding proteins and their biological functions." Veterinární Medicína 47, No. 2 - 3 (2012): 75–84. http://dx.doi.org/10.17221/5807-vetmed.

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Insulin-like growth factor (IGF-I, IGF-II) action is influenced by until today known eight forms of insulin-like growth factor binding proteins (IGFBPs). They have been obtained not only from some human and animal tissues and body fluids but also from conditioned medium of cell cultures. An important biological property of the IGFBPs is their ability to increase the circulating half-life of the IGFs. They are able to act as potentiators of cell proliferation. As IGFBPs bind to cell surfaces, they may act either to deliver the IGFs to those surfaces for activation of specific receptors or to ac

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2

Lee, Chang Hoon, Chin Saeng Cho, Kyung-You Park, et al. "The Role of Insulin-Like Growth Factor I and Binding Protein in Cholesteatoma Fibroblasts." Journal of Clinical Otolaryngology Head and Neck Surgery 14, no. 1 (2003): 113–17. http://dx.doi.org/10.35420/jcohns.2003.14.1.113.

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3

Leroith, Derek. "Insulin-like growth factor receptors and binding proteins." Baillière's Clinical Endocrinology and Metabolism 10, no. 1 (1996): 49–73. http://dx.doi.org/10.1016/s0950-351x(96)80298-9.

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4

Coverley, J. A., and R. C. Baxter. "Phosphorylation of insulin-like growth factor binding proteins." Molecular and Cellular Endocrinology 128, no. 1-2 (1997): 1–5. http://dx.doi.org/10.1016/s0303-7207(97)04032-x.

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5

Collet, Chris, and Judith Candy. "How many insulin-like growth factor binding proteins?" Molecular and Cellular Endocrinology 139, no. 1-2 (1998): 1–6. http://dx.doi.org/10.1016/s0303-7207(98)00078-1.

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6

Baxter, Robert C. "Insulin-like growth factor binding proteins as glucoregulators." Metabolism 44 (October 1995): 12–17. http://dx.doi.org/10.1016/0026-0495(95)90215-5.

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7

Bach, Leon A. "Insulin-like growth factor binding proteins 4-6." Best Practice & Research Clinical Endocrinology & Metabolism 29, no. 5 (2015): 713–22. http://dx.doi.org/10.1016/j.beem.2015.06.002.

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8

Purwana, Arie, Budiono Budiono, Jose RL Batubara, and Muhammad Faizi. "Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet." Journal of Biomedicine and Translational Research 6, no. 1 (2020): 6–10. http://dx.doi.org/10.14710/jbtr.v6i1.5474.

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Background: The vegan diet in children provides the benefit of reducing the risk of being overweight and improving the fat profile. The risk that can occur in the provision of a vegan diet in children is anthropometric size below reference and low caloric intake. Growth hormone (GH) and Insulin like Growth Factors (IGFs) are powerful stimulators for longitudinal growth of bone and require insulin-like growth factor binding protein (IGFBPs) which acts as a transport protein for IGF-1. A vegan diet with lower calorie intake in children has lower IGF-I levels than children with an omnivorous diet

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9

Ferry Jr., Robert J., Ruben W. Cerri, and Pinchas Cohen. "Insulin-Like Growth Factor Binding Proteins: New Proteins, New Functions." Hormone Research in Paediatrics 51, no. 2 (1999): 53–67. http://dx.doi.org/10.1159/000023315.

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10

Feld, Stella M., and Raimund Hirschberg. "Insulin-like growth factor-I and insulin-like growth factor-binding proteins in the nephrotic syndrome." Pediatric Nephrology 10, no. 3 (1996): 355–58. http://dx.doi.org/10.1007/s004670050124.

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11

Feld, Stella M., and Raimund Hirschberg. "Insulin-like growth factor-I and insulin-like growth factor-binding proteins in the nephrotic syndrome." Pediatric Nephrology 10, no. 3 (1996): 355–58. http://dx.doi.org/10.1007/bf00866783.

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12

Cara, José F. "Insulin-Like Growth Factors, Insulin-Like Growth Factor Binding Proteins and Ovarian Androgen Production." Hormone Research 42, no. 1-2 (1994): 49–54. http://dx.doi.org/10.1159/000184145.

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13

Rosen, Clifford J. "Serum Insulin-like Growth Factors and Insulin-like Growth Factor-binding Proteins: Clinical Implications." Clinical Chemistry 45, no. 8 (1999): 1384–90. http://dx.doi.org/10.1093/clinchem/45.8.1384.

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Abstract The last decade has been characterized by a major investigative thrust into the physiology of two unique but ubiquitous peptides, insulin-like growth factor (IGF)-I and IGF-II. The regulatory systems that control the tissue bioactivity of the IGFs have been delineated, and subcellular signaling mechanisms have been clarified. Clearly, both tissue and circulating growth factor concentrations are important in defining the relationship between IGF-I and cell activity. Bone, liver, and circulatory IGF-I have received the most attention by investigators, in part because of the ease of meas

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14

Bach, L. A., S. Hsieh, K. Sakano, H. Fujiwara, J. F. Perdue, and M. M. Rechler. "Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6." Journal of Biological Chemistry 268, no. 13 (1993): 9246–54. http://dx.doi.org/10.1016/s0021-9258(18)98342-0.

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15

Hwa, V., Y. Oh, and RG Rosenfeld. "Insulin-like growth factor binding proteins: a proposed superfamily." Acta Paediatrica 88, s428 (1999): 37–45. http://dx.doi.org/10.1111/j.1651-2227.1999.tb14349.x.

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16

Ranke, M. B., and M. Elmlinger. "Functional Role of Insulin-Like Growth Factor Binding Proteins." Hormone Research 48, no. 4 (1997): 9–15. http://dx.doi.org/10.1159/000191304.

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17

Holly, Jeff, and Claire Perks. "The Role of Insulin-Like Growth Factor Binding Proteins." Neuroendocrinology 83, no. 3-4 (2006): 154–60. http://dx.doi.org/10.1159/000095523.

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18

Conover, Cheryl A. "Insulin-like growth factor-binding proteins and bone metabolism." American Journal of Physiology-Endocrinology and Metabolism 294, no. 1 (2008): E10—E14. http://dx.doi.org/10.1152/ajpendo.00648.2007.

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Insulin-like growth factor-binding proteins (IGFBPs) are important regulators of bone metabolism. However, their precise roles are not fully understood, since IGFBPs can have both enhancing and inhibiting effects on IGF action, depending on context and posttranslational modifications, as well as IGF-independent effects. This review focuses on recent findings from cell culture, rodent models, and clinical studies concerning local IGFBP-2, IGFBP-4, and IGFBP-5 action in bone.

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19

D??ez, Javier, Concepci??n Laviades, Eduardo Mart??nez, et al. "Insulin-like growth factor binding proteins in arterial hypertension." Journal of Hypertension 13, no. 3 (1995): 349???356. http://dx.doi.org/10.1097/00004872-199503000-00011.

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20

Monget, P., N. Besnard, C. Huet, C. Pisselet, and D. Monniaux. "Insulin-Like Growth Factor-Binding Proteins and Ovarian Folliculogenesis." Hormone Research 45, no. 3-5 (1996): 211–17. http://dx.doi.org/10.1159/000184790.

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21

Rosenfeld, RG, H. Pham, P. Cohen, et al. "Insulin-like growth factor binding proteins and their regulation." Acta Paediatrica 83, s399 (1994): 154–58. http://dx.doi.org/10.1111/j.1651-2227.1994.tb13315.x.

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22

Ferry, R., L. Katz, Adda Grimberg, P. Cohen, and S. Weinzimer. "Cellular Actions of Insulin-Like Growth Factor Binding Proteins." Hormone and Metabolic Research 31, no. 02/03 (1999): 192–202. http://dx.doi.org/10.1055/s-2007-978719.

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23

Rechler, Matthew M., and David R. Clemmons. "Regulatory Actions of Insulin-like Growth Factor-binding Proteins." Trends in Endocrinology & Metabolism 9, no. 5 (1998): 176–83. http://dx.doi.org/10.1016/s1043-2760(98)00047-2.

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24

Chan, Kam, and E. Martin Spencer. "General aspects of insulin-like growth factor binding proteins." Endocrine 7, no. 1 (1997): 95–97. http://dx.doi.org/10.1007/bf02778072.

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25

Subramanian, Ashok, Anup Sharma, and Kefah Mokbel. "Insulin-like growth factor binding proteins and breast cancer." Breast Cancer Research and Treatment 107, no. 2 (2007): 181–94. http://dx.doi.org/10.1007/s10549-007-9549-0.

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26

Prosser, C. G., and R. D. McLaren. "Insulin-like growth factor binding proteins of equine serum." Biochemical and Biophysical Research Communications 189, no. 3 (1992): 1255–60. http://dx.doi.org/10.1016/0006-291x(92)90208-3.

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27

Hodgkinson, S. C., J. R. Napier, G. S. G. Spencer, and J. J. Bass. "Glycosaminoglycan binding characteristics of the insulin-like growth factor-binding proteins." Journal of Molecular Endocrinology 13, no. 1 (1994): 105–12. http://dx.doi.org/10.1677/jme.0.0130105.

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28

Ryu, Hye-Young, Hye-Jung Hwang, In-Hye Kim, Hong-Soo Ryu, and Taek-Jeong Nam. "Effects of Glucose on Insulin-like Growth Factor Binding-5 Expression in Human Fibroblasts." Journal of Life Science 17, no. 9 (2007): 1224–31. http://dx.doi.org/10.5352/jls.2007.17.9.1224.

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29

Grulich-Henn, J., J. Grulich-Henn, S. Spiess, et al. "Ligand Blot Analysis of Insulin-Like Growth Factor-Binding Proteins using Biotinylated Insulin-Like Growth Factor-I." Hormone Research in Paediatrics 49, no. 1 (1997): 1–7. http://dx.doi.org/10.1159/000023118.

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30

Rey, F., F. M. Rodríguez, N. R. Salvetti, et al. "Insulin-Like Growth Factor-II and Insulin-Like Growth Factor-Binding Proteins in Bovine Cystic Ovarian Disease." Journal of Comparative Pathology 142, no. 2-3 (2010): 193–204. http://dx.doi.org/10.1016/j.jcpa.2009.11.002.

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31

Tanaka, Reiko, Toshio Tsushima, Hitomi Murakami, Kazuo Shizume, and Takao Obara. "Insulin-like growth factor I receptors and insulin-like growth factor-binding proteins in human parathyroid tumors." World Journal of Surgery 18, no. 4 (1994): 635–41. http://dx.doi.org/10.1007/bf00353784.

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32

King, Jeffery L., and Clyde Guidry. "Insulin-Like Growth Factor Binding Proteins Modulate Müller Cell Responses to Insulin-Like Growth Factors." Investigative Opthalmology & Visual Science 45, no. 8 (2004): 2848. http://dx.doi.org/10.1167/iovs.04-0054.

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33

Hintz, R. L. "Role of Growth-Hormone and Insulin-Like Growth-Factor-Binding Proteins." Hormone Research 33, no. 2-4 (1990): 105–10. http://dx.doi.org/10.1159/000181492.

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34

Rosenfeld, Ron G., Vivian Hwa, Lisa Wilson, et al. "The Insulin-like Growth Factor Binding Protein Superfamily: New Perspectives." Pediatrics 104, Supplement_5 (1999): 1018–21. http://dx.doi.org/10.1542/peds.104.s5.1018.

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The insulin-like growth factor (IGF) binding proteins (IGFBPs) were initially identified as carrier proteins for IGF-I and IGF-II in a variety of biologic fluids. Their presumed function was to protect IGF peptides from degradation and clearance, increase the half-life of the IGFs, and deliver them to appropriate tissue receptors. The concept of IGFBPs as simple carrier proteins has been complicated, however, by a number of observations: 1) the six IGFBPs vary in their tissue expression and their regulation by other hormones and growth factors; 2) the IGFBPs are subjected to proteolytic degrad

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35

Chen, T. L., L. Y. Chang, D. A. DiGregorio, A. J. Perlman, and Y. F. Huang. "Growth factor modulation of insulin-like growth factor-binding proteins in rat osteoblast-like cells." Endocrinology 133, no. 3 (1993): 1382–89. http://dx.doi.org/10.1210/endo.133.3.7689954.

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36

Bach, Leon A., Ping Fu, and Zhiyong Yang. "Insulin-like growth factor-binding protein-6 and cancer." Clinical Science 124, no. 4 (2012): 215–29. http://dx.doi.org/10.1042/cs20120343.

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The IGF (insulin-like growth factor) system is essential for physiological growth and it is also implicated in a number of diseases including cancer. IGF activity is modulated by a family of high-affinity IGF-binding proteins, and IGFBP-6 is distinctive because of its marked binding preference for IGF-II over IGF-I. A principal role for IGFBP-6 is inhibition of IGF-II actions, but recent studies have indicated that IGFBP-6 also has IGF-independent effects, including inhibition of angiogenesis and promotion of cancer cell migration. The present review briefly summarizes the IGF system in physio

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37

Haugaard, Steen B., Ove Andersen, Birgitte R. Hansen, et al. "Insulin-like growth factors, insulin-like growth factor-binding proteins, insulin-like growth factor-binding protein-3 protease, and growth hormone-binding protein in lipodystrophic Human Immunodeficiency Virus-infected patients." Metabolism 53, no. 12 (2004): 1565–73. http://dx.doi.org/10.1016/j.metabol.2004.06.025.

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38

Murphy, LJ. "Insulin-like growth factor-binding proteins: functional diversity or redundancy?" Journal of Molecular Endocrinology 21, no. 2 (1998): 97–107. http://dx.doi.org/10.1677/jme.0.0210097.

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39

Zapf, Jürgen. "Physiological role of the insulin-like growth factor binding proteins." European Journal of Endocrinology 132, no. 6 (1995): 645–54. http://dx.doi.org/10.1530/eje.0.1320645.

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40

Levitt Katz, Lorraine E., Ron G. Rosenfeld, and S. Pinchas Cohen. "Clinical Significance of Insulin-Like Growth Factor Binding Proteins (IGFBPs)." Endocrinologist 5, no. 1 (1995): 36–43. http://dx.doi.org/10.1097/00019616-199501000-00006.

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41

Sureshbabu, Angara, Elizabeth Tonner, and David J. Flint. "Insulin-like growth factor binding proteins and mammary gland development." International Journal of Developmental Biology 55, no. 7-8-9 (2011): 781–89. http://dx.doi.org/10.1387/ijdb.113364as.

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42

Lamson, George, Linda C. Giudice, and Ron G. Rosenfeld. "Insulin-Like Growth Factor Binding Proteins: Structural and Molecular Relationships." Growth Factors 5, no. 1 (1991): 19–28. http://dx.doi.org/10.3109/08977199109000268.

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43

Firth, Sue M., and Robert C. Baxter. "Cellular Actions of the Insulin-Like Growth Factor Binding Proteins." Endocrine Reviews 23, no. 6 (2002): 824–54. http://dx.doi.org/10.1210/er.2001-0033.

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44

Camacho-Hübner, Cecilia. "Insulin-like growth factor-binding proteins and neoplasia: an overview." Growth Hormone & IGF Research 10 (January 2000): S14—S15. http://dx.doi.org/10.1016/s1096-6374(00)90006-6.

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45

Kim, Ho-Seong, Ron G. Rosenfeld, and Youngman Oh. "Biological roles of insulin-like growth factor binding proteins (IGFBPs)." Experimental & Molecular Medicine 29, no. 2 (1997): 85–96. http://dx.doi.org/10.1038/emm.1997.13.

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46

Veomett, George E., Lora L. Munger, Gary L. Smith, and Judith E. Schollmeyer. "Heterogeneity of insulin-like growth factor binding proteins in swine." Molecular and Cellular Endocrinology 65, no. 1-2 (1989): 49–57. http://dx.doi.org/10.1016/0303-7207(89)90164-0.

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47

Wetterau, Lawrence A., Michael G. Moore, Kuk-Wah Lee, Melanie L. Shim, and Pinchas Cohen. "Novel Aspects of the Insulin-like Growth Factor Binding Proteins." Molecular Genetics and Metabolism 68, no. 2 (1999): 161–81. http://dx.doi.org/10.1006/mgme.1999.2920.

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48

Yamanaka, Yoshitaka, Elizabeth M. Wilson, Ron G. Rosenfeld, and Youngman Oh. "Inhibition of Insulin Receptor Activation by Insulin-like Growth Factor Binding Proteins." Journal of Biological Chemistry 272, no. 49 (1997): 30729–34. http://dx.doi.org/10.1074/jbc.272.49.30729.

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49

Lakatos, Peter, Janos Foldes, Zsolt Nagy, et al. "Serum Insulin-Like Growth Factor-I, Insulin-Like Growth Factor Binding Proteins, and Bone Mineral Content in Hyperthyroidism." Thyroid 10, no. 5 (2000): 417–23. http://dx.doi.org/10.1089/thy.2000.10.417.

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50

Nakamura, Michio, Shin’ichi Miyamoto, Hiroyuki Maeda, et al. "Matrix metalloproteinase-7 degrades all insulin-like growth factor binding proteins and facilitates insulin-like growth factor bioavailability." Biochemical and Biophysical Research Communications 333, no. 3 (2005): 1011–16. http://dx.doi.org/10.1016/j.bbrc.2005.06.010.

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