Academic literature on the topic 'Intact phospholipids'

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Journal articles on the topic "Intact phospholipids"

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Ronco, A. M., and L. E. Valladares. "Phospholipid methylation decreases in human chorionic gonadotrophin-induced desensitized rat Leydig cells." Journal of Endocrinology 138, no. 1 (1993): 65–71. http://dx.doi.org/10.1677/joe.0.1380065.

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ABSTRACT Phospholipid methylation in Leydig cells from desensitized rats was studied. The incorporation of l-[methyl-3H] methionine into phospholipids in intact Leydig cells decreased when animals were injected with a single high dose of human chorionic gonadotrophin (hCG). This effect was detected on the first day after hCG injection and remained up to 12 days after treatment. The inhibition was not due to a reduced uptake of l-[methyl-3H]methionine. A decreased phospholipid methylation with unaltered phospholipid methyltransferase activity was observed on days 1, 6 and 12 after the hCG. On d
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Heinzelmann, Sandra M., Nicole J. Bale, Ellen C. Hopmans, Jaap S. Sinninghe Damsté, Stefan Schouten, and Marcel T. J. van der Meer. "Critical Assessment of Glyco- and Phospholipid Separation by Using Silica Chromatography." Applied and Environmental Microbiology 80, no. 1 (2013): 360–65. http://dx.doi.org/10.1128/aem.02817-13.

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ABSTRACTPhospholipid-derived fatty acids (PLFAs) are commonly used to characterize microbial communitiesin situand the phylogenetic positions of newly isolated microorganisms. PLFAs are obtained through separation of phospholipids from glycolipids and neutral lipids using silica column chromatography. We evaluated the performance of this separation method for the first time using direct detection of intact polar lipids (IPLs) with high-performance liquid chromatography–mass spectrometry (HPLC-MS). We show that under either standard or modified conditions, the phospholipid fraction contains not
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Yoshino, Jun-ichiro, Yasumasa Sugiyama, Shohei Sakuda, et al. "Chemical Structure of a Novel Aminophospholipid from Hydrogenobacter thermophilus Strain TK-6." Journal of Bacteriology 183, no. 21 (2001): 6302–4. http://dx.doi.org/10.1128/jb.183.21.6302-6304.2001.

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ABSTRACT The phospholipid composition of Hydrogenobacter thermophilus strain TK-6, an obligately chemolithoautotrophic, extremely thermophilic hydrogen bacterium, was analyzed. Two of four phospholipids detected from the strain were assumed to be phosphatidylinositol and phosphatidylglycerol. An aminophospholipid named PX, whose content among the phospholipids was 65%, was found to have a novel chemical structure by analysis of the dilyso form with nuclear magnetic resonance and fast atom bombardment-mass spectrometry (FAB-MS) and by analysis of the intact PX with FAB-MS as 1,2-diacyl-3-O-(pho
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Wallace, A. V., and N. J. Kuhn. "Incorporation into phospholipid vesicles of pore-like properties from Golgi membranes of lactating-rat mammary gland." Biochemical Journal 236, no. 1 (1986): 91–96. http://dx.doi.org/10.1042/bj2360091.

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The ability of rat mammary-gland Golgi membranes to produce monosaccharide-specific pores in phospholipid vesicles was investigated. The apparent ability of Triton X-100 extracts of Golgi membranes to form such pores was re-evaluated, since we have now found that an apparent pore is produced by the detergent alone. We therefore incorporated intact Golgi membranes (1 mg of protein) into egg-yolk phospholipid vesicles by direct sonication in the absence of any detergent. These vesicles retained about 0.6% of the total sucrose, but demonstrated selective permeability towards glucose compared with
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Mazzeo, A. R., J. Nandi, and R. A. Levine. "Effects of ethanol on parietal cell membrane phospholipids and proton pump function." American Journal of Physiology-Gastrointestinal and Liver Physiology 254, no. 1 (1988): G57—G64. http://dx.doi.org/10.1152/ajpgi.1988.254.1.g57.

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The effects of ethanol on membrane phospholipids of isolated rabbit parietal cells (PC) and fundic glands (FG) were evaluated by using proton nuclear magnetic resonance spectroscopy (NMR). The most conspicuous resonance bands in PC and FG spectra at 3.2 and 0.9 ppm were due to the protons of +N(CH3)3 groups of phosphatidylcholine and, to a lesser degree, other phospholipid derivatives and terminal -CH3 groups for all phospholipids, respectively. Ethanol treatment (1 min) of PC and FG at 37 degrees C significantly increased the peak intensity of -CH3 groups in a dose-dependent manner, while no
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Pan, Yue, Lei Zhang, Xuanfei Fu, et al. "Addition of Phospholipids Improved the Physical Stability and Fat Globule Structure of Processed Milk." Foods 14, no. 3 (2025): 375. https://doi.org/10.3390/foods14030375.

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The manufacturing processes for infant formula disrupt the structure of phospholipid-coated milk fat globules, thereby impacting the physical stability of the system. In this study, either soybean phospholipids (SPs) or egg yolk phospholipids (EYPs) were incorporated into the milk system to reduce this damage, and their effects on the stability and fat globule structure of processed milk were examined. The findings revealed that the addition of phospholipids improved the physical stability and fat globule structure of different processed milk. In pasteurized milk, the stability constant of sam
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SPICKETT, Corinne M., Nicola RENNIE, Helen WINTER, et al. "Detection of phospholipid oxidation in oxidatively stressed cells by reversed-phase HPLC coupled with positive-ionization electroscopy MS." Biochemical Journal 355, no. 2 (2001): 449–57. http://dx.doi.org/10.1042/bj3550449.

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Measurement of lipid peroxidation is a commonly used method of detecting oxidative damage to biological tissues, but the most frequently used methods, including MS, measure breakdown products and are therefore indirect. We have coupled reversed-phase HPLC with positive-ionization electrospray MS (LC-MS) to provide a method for separating and detecting intact oxidized phospholipids in oxidatively stressed mammalian cells without extensive sample preparation. The elution profile of phospholipid hydroperoxides and chlorohydrins was first characterized using individual phospholipids or a defined p
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Tsueshita, Takaya, Salil Gandhi, Hayat Önyüksel, and Israel Rubinstein. "Phospholipids modulate the biophysical properties and vasoactivity of PACAP-(1—38)." Journal of Applied Physiology 93, no. 4 (2002): 1377–83. http://dx.doi.org/10.1152/japplphysiol.00277.2002.

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The purpose of this study was to elucidate the interactions between pituitary adenylate cyclase-activating peptide (PACAP)-(1—38) and phospholipids in vitro and to determine whether these phenomena modulate, in part, the vasorelaxant effects of the peptide in the intact peripheral microcirculation. We found that the critical micellar concentration of PACAP-(1—38) was 0.4–0.9 μM. PACAP-(1—38) significantly increased the surface tension of a dipalmitoylphosphatidylcholine monolayer and underwent conformational transition from predominantly random coil in saline to α-helix in the presence of dist
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Maraldi, N. M., S. Santi, N. Zini, et al. "Decrease in nuclear phospholipids associated with DNA replication." Journal of Cell Science 104, no. 3 (1993): 853–59. http://dx.doi.org/10.1242/jcs.104.3.853.

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Lipid metabolism in nuclei is very active and appears involved in the transduction of signals to the genome in response to agonists acting at the plasma membrane level. However, the precise topology of nuclear lipid metabolism and the relationship between nuclear lipids and crucial events of the cell function, such as DNA replication, have not been fully elucidated. By using a recently developed cytochemical method for detecting phospholipids inside the nucleus of intact cells at the electron microscope level, we have analyzed the changes in intranuclear phospholipids in DNA-replicating versus
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Banliat, Charles, Daniel Le Bourhis, Ophélie Bernardi, et al. "Oviduct Fluid Extracellular Vesicles Change the Phospholipid Composition of Bovine Embryos Developed In Vitro." International Journal of Molecular Sciences 21, no. 15 (2020): 5326. http://dx.doi.org/10.3390/ijms21155326.

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Oviduct fluid extracellular vesicles (oEVs) have been proposed as bringing key molecules to the early developing embryo. In order to evaluate the changes induced by oEVs on embryo phospholipids, fresh bovine blastocysts developed in vitro in the presence or absence of oEVs were analyzed by intact cell MALDI-TOF (Matrix assisted laser desorption ionization—Time of flight) mass spectrometry (ICM-MS). The development rates, cryotolerance, and total cell number of blastocysts were also evaluated. The exposure to oEVs did not affect blastocyst yield or cryotolerance but modified the phospholipid co
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Dissertations / Theses on the topic "Intact phospholipids"

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Popendorf, Kimberly J. (Kimberly Julia). "Marine microbial intact polar diacylglycerolipids and their application in the study of nutrient stress and bacterial production." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/79293.

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Thesis (Ph. D.)--Joint Program in Oceanography/Applied Ocean Science and Engineering (Massachusetts Institute of Technology, Dept. of Biology; and the Woods Hole Oceanographic Institution), February 2013.<br>"February 2013." Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Intact polar diacylglycerolipids (IP-DAGs) were used to study microbial dynamics in the surface ocean. IP-DAGs from surface ocean seawater were quantified using high performance liquid chromatography-mass spectrometry (HPLC-MS), after first developing a sensitive, high throughput molecular ion
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Ford, Rosalyn Claire. "Fatty acid status and dietary intake of children and their caregivers from three distinct communities / Rosalyn Claire Ford." Thesis, 2013. http://hdl.handle.net/10394/10722.

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Background: Dietary fat intake particularly of omega-3 and omega-6 fatty acids play an important role in growth and development and influence the risk of nutrition related non communicable diseases. These dietary intakes are reflected in the red blood cell (RBC) fatty acid profile. Aim: The aim of this study was to assess the fatty acid profile (%) of red blood cell membrane phospholipids in relation to the dietary intake of South African children aged 2 to 5 years, and of their mothers/caregivers from three communities, each with distinct dietary patterns. Method: In this cross-sectional obse
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Huang, Yu-Fen, and 黃郁芬. "Obesity-associated alterations of pancreatic phospholipid metabolism and insulin secretion of broiler breeder hens under voluntary feed intake-a study of cell self-defensive mechanisms." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/81687447186491879583.

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碩士<br>中興大學<br>動物科學系所<br>99<br>Genetic selection for rapid growth is accompanied by a loss of satiety regulation and energy homeostasis leading to a propensity of hyperphagia and obesity in modern broiler chickens. Obesity results in excessive fatty acid accumulation in non-adipose tissues leading to inflammatory responses, oxidative damage due to excessive β-oxidation, and bioactive lipid derivatives may cause cell dysfunction or apoptosis. This phenomenon is called “lipotoxicity”. In contrast to mammals, birds are characterized by hyperglycemia, hyperinsulinemia, and insulin resistance. Chron
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Books on the topic "Intact phospholipids"

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Thornton, Clare, and Justin Mason. Vascular biology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0057.

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Vascular biology is the study of the physiology of the vasculature and how it may be the target for disease processes. An understanding of vascular biology is central to the study of rheumatic disease for three reasons: it is an integral part of a functioning immune system; it is the primary site of pathology in many conditions; and it is the site of the important secondary complications of chronic inflammation, endothelial dysfunction and atherosclerosis. Vascular biology requires a detailed knowledge of the anatomy and physiology of the vasculature and its constituent vessels. The multistep
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Thornton, Clare, and Justin Mason. Vascular biology. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199642489.003.0057_update_001.

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Vascular biology is the study of the physiology of the vasculature and how it may be the target for disease processes. An understanding of vascular biology is central to the study of rheumatic disease for three reasons: it is an integral part of a functioning immune system; it is the primary site of pathology in many conditions; and it is the site of the important secondary complications of chronic inflammation, endothelial dysfunction and atherosclerosis. Vascular biology requires a detailed knowledge of the anatomy and physiology of the vasculature and its constituent vessels. The multistep
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Book chapters on the topic "Intact phospholipids"

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Sergeant, Susan, and Linda C. McPhail. "Measurement of Phospholipid Metabolism in Intact Neutrophils." In Neutrophil Methods and Protocols. Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-467-4_6.

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Sergeant, Susan, and Linda C. McPhail. "Measurement of Phospholipid Metabolism in Intact Neutrophils." In Neutrophil Methods and Protocols. Humana Press, 2014. http://dx.doi.org/10.1007/978-1-62703-845-4_7.

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Davis, John S., Leigh A. West, and Laura L. Weakland. "Evidence for an Endogenous Activator of Inositol Phospholipid Phospholipase C in Intact Rat Corpora Lutea." In Growth Factors and the Ovary. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5688-2_45.

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Hatipoglu, Abdulkerim. "Brain and Nutrition." In Brain Biochemistry and Its Disease. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359371.7.

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In the current section, the functions of nutrients such as polyunsaturated fatty acids (PUFAs), B group vitamins, calcium, zinc, iron, magnesium in the brain and the effect of diet on neurodegenerative diseases such as Alzheimer’s, Parkinson’s, Amyotrophic Lateral Sclerosis and Multiple Sclerosis are discussed. PUFAs (Linoleic acid, α-Linoleic acid, eicosapentaenoic acid and docosahexaenoic acid), which maintain membrane fluidity necessary for synaptic vesicle fusion and neurotransmitter transmission within neural networks, are essential components of neuronal cell membranes. In older brains,
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Holub, Bruce J., and Steve P. Watson. "Methods for measuring agonist-induced phospholipid metabolism in intact human platelets." In Platelets. Oxford University PressOxford, 1996. http://dx.doi.org/10.1093/oso/9780199635382.003.0012.

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Abstract Stimulation of platelets by agonists causes marked alterations in phospholipid metabolism (1,2). The activation of phospholipase C results in the degradation of phosphoinositides, noteably phosphatidylinositol 4,5-bisphosphate (PI 4,5-P2), resulting in the production of the second messengers diacylglycerol (DG) and inositol 1,4,5-trisphosphate (Ins l,4,5-P3) (3,4). DG is further metabolized to phosphatidic acid (PA) via DG kinase. In addition to PI 4,5-P2 hydrolysis via phospholipase C with agonist stimulation, phosphatidylinositol (PI) is sequentially phosphorylated upon receptor occ
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Christie, William W., and Xianlin Han. "Chromatographic analysis of molecular species of intact phospholipids and glycolipids." In Lipid Analysis. Elsevier, 2012. http://dx.doi.org/10.1533/9780857097866.245.

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Geiger, Benjamin. "Vinculin." In Guidebook to the Cytoskeletal and Motor Proteins. Oxford University PressOxford, 1999. http://dx.doi.org/10.1093/oso/9780198599579.003.0055.

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Abstract Vinculin is an anchor protein which is specifically associated with ce/1-ECM adhesions such as focal contacts as well as with adherens type cell-eel/ junctions. In both sites, vinculin participates in the formation of a submembrane ‘plaque’ structure which is responsible for the attachment of actin filaments to the plasma membrane. Biochemical and molecular genetic analyses of intact vinculin or vinculin fragments suggested that the molecule can interact with a variety of cytoskeletal and anchor proteins. Furthermore, it is shown that vinculin may exist in folded (head-to-tail) and un
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Hanley, Michael R., David R. Poyner, and Phillip T. Hawkins. "[13] Inositol phospholipids and phosphates for investigation of intact cell phospholipase C substrates and products." In Methods in Enzymology. Elsevier, 1991. http://dx.doi.org/10.1016/0076-6879(91)97141-k.

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Evershed, Richard P. "Gas chromatography of lipids." In Lipid Analysis. Oxford University PressOxford, 1992. http://dx.doi.org/10.1093/oso/9780199630981.003.0004.

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Abstract Gas chromatography is used extensively in the analysis of all the major lipid classes. In many instances GC analyses are performed on intact molecular species. However, for involatile or thermally unstable substances, such as phospholipids, chemical or enzymatic degradations must be used to release their simpler lipid moieties, as these are more amenable to GC analysis. (See Chapter 2 for accounts of degradation and derivatization methods commonly employed in the analysis of lipids.) This is a practical account of GC techniques used in lipid analysis. Wall¬ coated open tubular (WCOT)
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Hanahan, Donald J. "Phospholipid(s) Associations in Cellular Structures." In A Guide to Phospholipid Chemistry. Oxford University Press, 1997. http://dx.doi.org/10.1093/oso/9780195079814.003.0005.

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In the preceding chapter, the intent was to provide the reader with a broad perspective on the chemical characteristics of cellular phospholipids. At the same time, emphasis was placed on the potential usefulness of this information in dissecting the importance of phospholipids in cellular events, such as signal transduction. There is no doubt that the large number of observations reported on the close relationship of phospholipids to the transduction process has stimulated a widespread (and gratifying) interest in these compounds. Certainly it is very clear now that stimulus-induced activatio
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Conference papers on the topic "Intact phospholipids"

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Labow, R. S., E. Meek, G. A. Adams, and G. Rock. "AGGREGATION RESPONSE OF PLATELETS DURING INHIBITION OF PHOSPHOLIPASE A2." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644542.

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Arachidonic acid (AA) is liberated from platelet membrane phospholipids during stimulation and promotes cellular aggregation through the synthesis of thromboxane A2. Two pathways; phospholipase A2 (PLA2) or phospholipase C (PLC) followed by the action of acylglycerolipases, are thought to be activated during platelet stimulation and supply the necessary AA. We have reported that mono (2-ethylhexyl)phthalate (MEHP), a physiological metabolite of the plasticizer di(2-ethylhexyl)-phthalate (DEHP), commonly used in a variety of medical devices and storage containers, inhibits PLA2, but not PLC in
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Webley, Ann-Dorie, Stephanie Dungan, and Susan Ebeler. "Local distribution of limonene in phospholipid vesicles." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/qxcj6124.

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The efficacy and quality of food products is affected by the distribution of hydrophobic solutes such as flavours and bioactive compounds. In order to improve food design, it is important to determine the local distribution of these solutes and the factors that affect their stability, incorporation and release. Colloidal assemblies of phospholipids are of particular interest, as they comprise safe, widespread natural amphiphiles that can solubilize hydrophobic compounds. However, there is a lack of accurate and non-destructive methods to study the local distribution of solutes between the samp
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Dugo, Paola, Francesca Rigano, and Luigi Mondello. "Lipidomic analysis in food: The role of a detailed elucidation of intact lipids in functional foods for investigating on nutritional aspects." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/chnd8051.

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The growing demand in natural matrices, representing a source of dietary and nutraceutical molecules, placed, as direct consequence, the urgent need for the development of suitable analytical methods able to provide a comprehensive characterization of both “conventional” and “unconventional” products. In the last decades, lipidomic has emerged as a cutting-edge approach among omics- techniques, since lipids revealed to be essential molecules in the regulation of metabolic pathways. To this regard, the content of essential fatty acids (EFAs), as well as nutritional indices such as the levels of
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BLACHE, D., and M. CIAVATTI. "ARACHIDONATE METABOLISM IN RAT PLATELETS IN THE PRESENCE OF Ca2+-SUBSTITUTES (Sr2+, BA2+)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643392.

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To further document the involvement of external Ca2+ in the platelet induced-activation process, we have studied the arachidonate (AA) metabolism of intact washed rat platelets in the presence of different concentrations of Ca2+, Sr2+ or Ba2+. The thrombin-induced mobilization of [3H]- or [14C]-AA preincorporated into platelet phospholipids was followed as well as the subsequent formation of labeled cyclooxygenase and lipoxygenase products (CLP). Results indicate that upon thrombin (&lt;0.1 U/ml) stimulation, AA release and CLP formation are reduced by 50 to 90% only by omission of Ca2+ as com
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Krishnaswamy, S., and K. G. Mann. "FLUORESCENCE STUDIES OF THE BINDING OF FACTOR Va TO PHOSPHOLIPID VESICLES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643882.

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The free sulphydryl groups in factor Va were analyzed under native and denaturing conditions using dithio-bis-nitrobenzoic acid (DTNB). The heavy chain (D) and the light chain (E) of factor Va were found to contain one free sulphydryl each under native conditions and following denaturation. Intact factor Va contained two free sulphydryls after denaturation while only one of these groups was accessible to DTNB under native conditions. Analysis of the rates of modification of the accessible sulphydryl in factor Va, and direct visualization of factor Va reacted with fluorescent sulphydryl modifie
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Suga, K., Y. Uemura, T. Tsuijinaka, M. Sakon, J. Kambayashi, and T. Mori. "PROPERTIES OF PHOSPHATIDYLINOSITOL KINASE IN HUMAN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643807.

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We have reported the specific 32P-labelling in phosphatidyl-inositol-4-monophosphate(PIP) of intact platelets upon addition of the agents which elevate intracellular cAMP (Thrombos.Res.44, 155,1986).This event may be catalyzed by the action of Pl-kinase, the properties of which has not been elucidatedyet.Thereby, attempts were made to assay and to characterize PI-kinase of human platelets.Fresh lysed platelets prelabelled with 32P in cold Tris-HCl buffer containing 2mM EGTA were incubated at 37 C in the presence of MgCl2 for designated times and the phospholipids were extracted and analyzed by
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de Four, N. J., R. M. Bertina, and F. Havgrkate. "STIMULATION OF FIBRINOLYSIS BY ACTIVATED PROTEIN C (APC)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642961.

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In 1960 Mammen and Seegers reported the discovery of a new protein (autoprothrombin II-A, APC) with both anticoagulant and profibrinolytic activity. They found that APC accelerated clot lysis in vitro and proposed that this was due to a reduction of plasmin - inhibitory activity. Many years later Comp et al (J Clin Inv 68: 1221) reported that the infusion of APC into dogs resulted in an increase in circulating plasminogen activator activity. This observation stimulated more extensive studies of the profibrinolytic effects of APC.In our laboratories we have studied the effect of human APC on cl
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Nakashima, S., T. Tohmatsu, H. Hattori, A. Suganuma, and Y. Nozawa. "EVIDENCE FOR INVOLVEMENT OF GTP-BINDING PROTEIN IN ARACKIDONIC ACID RELEASE BY PHOSPHOLIPASE A2 IN PERMEABILIZED HUMAN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644631.

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Platelet activation is accompanied by the active metabolism of membrane phospholipids. Phosphoinositide breakdown by phospholipase C generates second messengers; inositol trisphosphate and diacylglycerol. Recently, it is suggested that GTP-binding protein is linked to the activation of phospholipase C as is true for adenylate cyclase. Although it is known that the receptor stimulation by agonists leads to generation of arachidonic acid, its molecular mechanism has not yet been clear. However, several studies in neutrophils and mast cells using pertussis toxin, have shown the possibility that a
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Norϕ, A., T. Smimonsen, K. Ytre-Arene, B. Lyngmo, and B. Svensson. "THE EFFECT OF TWO CHOLESTEROL-LOWERING AGENTS ON PLATELETS IN PATIENTS WITH HYPERCHOLESTEROLEMIA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643801.

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Twenty-one subjects with type Ila hyperlipoproteinemia, receiving dietary treatment were given Synvinolin (MK-733), a HMG-CoA reductase inhibitor, 40 mg or Cholestyramin (Questran) 24 g daily for a period of 12 weeks.Serum lipids, platelet cholesterol, phospholipids and fatty acid composition and platelet function were measured before and after the intake of the two drugs.Both drugs reduced serum total cholesterol with approximately 50%. No significant changes were observed in platelet lipid concentrations or in the primary bleeding time. Collagen induced aggregation and thromboxane (TXA2) pro
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Simonsen, T., Å. Vårtun, V. Lyngmo, G. Hornstra, and A. Nordøy. "SERUM PREPARED AFTER DAILY INTAKE OF FISH INHIBITS PGI-2 PRODUCTION BUT NOT PLATELET INHIBITORY ACTIVITY OF ENDOTHELIAL CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643401.

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Healthy males were given dietary supplement of 100 g mackerelpasta for six weeks. Controlls were given meatpasta. Blood were collected before and at the end of the dietary intervention. Fatty acid composition of total phospholipids in serum and free fatty acids were measured by GLCHuman endothelium cells were grown in medium supplemented with 10% serum prepared from blood of the mackerel and controll groups. The medium was then examined for PGI-2 by RIA of 6-Keto-PGFIα , and for platelet aggregation inhibitory activity (PAIA) measured as inhibition of collagen induced platelet aggregation in p
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Reports on the topic "Intact phospholipids"

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Naim, Michael, Andrew Spielman, Shlomo Nir, and Ann Noble. Bitter Taste Transduction: Cellular Pathways, Inhibition and Implications for Human Acceptance of Agricultural Food Products. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7695839.bard.

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Historically, the aversive response of humans and other mammals to bitter-taste substances has been useful for survival, since many toxic constituents taste bitter. Today, the range of foods available is more diverse. Many bitter foods are not only safe for consumption but contain bitter constituents that provide nutritional benefits. Despite this, these foods are often eliminated from our current diets because of their unacceptable bitterness. Extensive technology has been developed to remove or mask bitterness in foods, but a lack of understanding of the mechanisms of bitterness perception a
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Butler, Walter R., Uzi Moallem, Amichai Arieli, Robert O. Gilbert, and David Sklan. Peripartum dietary supplementation to enhance fertility in high yielding dairy cows. United States Department of Agriculture, 2007. http://dx.doi.org/10.32747/2007.7587723.bard.

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Objectives of the project: To evaluate the effects of a glucogenic supplement during the peripartum transition period on insulin, hepatic triglyceride accumulation, interval to first ovulation, and progesterone profile in dairy cows. To compare benefits of supplemental fats differing in fatty acid composition and fed prepartum on hepatic triglyceride accumulation, interval to first ovulation, progesterone profile, and uterine prostaglandin production in lactating dairy cows. To assess the differential and carry-over effects of glucogenic and fat supplements fed to peripartum dairy cows on ster
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