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Journal articles on the topic 'Integration versus selection'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Doi, Keitarou, Xiaolin Wu, Yuko Taniguchi, et al. "Preferential selection of human T-cell leukemia virus type I provirus integration sites in leukemic versus carrier states." Blood 106, no. 3 (2005): 1048–53. http://dx.doi.org/10.1182/blood-2004-11-4350.

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Abstract Human T-cell leukemia virus type I (HTLV-I) is a causative agent of neoplastic disease, adult T-cell leukemia (ATL). Although the encoding viral proteins play an important role in oncogenesis, the role of the HTLV-I proviral integration site remains unsolved. We determined the integration sites of HTLV-I proviruses in ATL cells and HTLV-I–infected cells in asymptomatic carriers. In carrier and ATL cells, HTLV-I provirus was integrated into the transcriptional unit at frequencies of 26.8% (15/56) and 33.9% (20/59), respectively, which were equivalent to the frequency calculated based o

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2

Archer, John. "Refining the sexual selection explanation within an ethological framework." Behavioral and Brain Sciences 32, no. 3-4 (2009): 292–311. http://dx.doi.org/10.1017/s0140525x09990963.

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AbstractMy response is organized into three sections. The first revisits the theme of the target article, the explanatory power of sexual selection versus social role theory. The second considers the range and scope of sexual selection, and its application to human sex differences. Two topics are examined in more detail: (1) the paternity uncertainty theory of partner violence; (2) evolution of inter-group aggression. Section 4 covers ultimate and proximal explanations and their integration within an ethological approach. I consider the development of sex differences in aggression, and their c

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3

Ban, Zhuo. "Laboring Under the Cross." Management Communication Quarterly 31, no. 2 (2016): 230–57. http://dx.doi.org/10.1177/0893318916680905.

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This study used Bakhtinean dialogism and contrapuntal analysis to examine how organizational identity in a Christian house church in China emerged through the interplay of competing discourses. I identified three sets of tensions: (a) religiosity versus secularity, (b) profit versus service, and (c) labor versus management. Church organizers and core members used many strategies to mitigate these tensions, including selection, separation, integration, and transcendence. Marginalized workers further complicated this discursive tension in resistance to a managerial monologue. The collective iden

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Malaj, Doris. "The Influence of European Identity on Integration Efforts." Interdisciplinary Journal of Research and Development 10, no. 2 (2023): 89. http://dx.doi.org/10.56345/ijrdv10n213.

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The EU's recurrent crises underline its complex and debated nature. Truly grasping its intricacies is key to understanding the tie between European identity and integration. Central to the discourse are questions on whether a shared European identity influences member selection or if the emphasis is on upholding democratic values. Academic discussions have often overlooked a holistic examination of integration processes, treating EU expansions as standalone events without delving deep into the relationship between integration and European identity. This paper posits that the absence of a unifi

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Drira, Sabrine, Frida Ben Rais Lasram, Tarek Hattab, Yunne-Jai Shin, Amel Ben Rejeb Jenhani, and François Guilhaumon. "Can We Avoid Tacit Trade-Offs between Flexibility and Efficiency in Systematic Conservation Planning? The Mediterranean Sea as a Case Study." Diversity 14, no. 1 (2021): 9. http://dx.doi.org/10.3390/d14010009.

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Species distribution models (SDMs) provide robust inferences about species-specific site suitability and are increasingly used in systematic conservation planning (SCP). SDMs are subjected to intrinsic uncertainties, and conservation studies have generally overlooked these. The integration of SDM uncertainties in conservation solutions requires the development of a suitable optimization algorithm. Exact optimization algorithms grant efficiency to conservation solutions, but most of their implementations generate a single binary and indivisible solution. Therefore, without variation in their pa

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O'Brien, Janelle Viera, and Christopher D. Wickens. "Free Flight Cockpit Displays of Traffic and Weather: Effects of Dimensionality and Data Base Integration." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 41, no. 1 (1997): 18–22. http://dx.doi.org/10.1177/107118139704100105.

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In any Free Flight system, pilots must have displays which effectively depict traffic and weather information as more and more responsibility for separation from such hazards transfers from air traffic controllers to pilots. This research effort seeks to address the issues of dimensionality (3D versus 2D coplanar displays) and data base integration (separation or integration of traffic and weather information within displays). Seventeen general aviation flight instructors flew a series of en route trials with four display types in which dimensionality, data base integration, and hazard geometr

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Pfennig, Karin S., David W. Pfennig, Cody Porter, and Ryan A. Martin. "Sexual selection's impacts on ecological specialization: an experimental test." Proceedings of the Royal Society B: Biological Sciences 282, no. 1807 (2015): 20150217. http://dx.doi.org/10.1098/rspb.2015.0217.

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In many species, individuals specialize on different resources, thereby reducing competition. Such ecological specialization can promote the evolution of alternative ecomorphs—distinct phenotypes adapted for particular resources. Elucidating whether and how this process is influenced by sexual selection is crucial for understanding how ecological specialization promotes the evolution of novel traits and, potentially, speciation between ecomorphs. We evaluated the population-level effects of sexual selection (as mediated by mate choice) on ecological specialization in spadefoot toad tadpoles th

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8

Rosener, William Joseph. "Comparative Analysis of Google Sheets and Microsoft Excel." Journal of Cases on Information Technology 26, no. 1 (2024): 1–21. http://dx.doi.org/10.4018/jcit.351672.

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An emerging landscaping and lawn care service company (GreenLawn) is seeking to transition from manual record-keeping to digital solutions. With significant growth over two years, GreenLawn requires efficient software to manage operations and finances while avoiding complexity and extensive training costs. The company evaluates Microsoft Excel and Google Sheets, weighing features, collaboration capabilities, ease of use, and pricing. GreenLawn's specific needs include service scheduling, workforce management, client information storage, inventory tracking, marketing, expense tracking, and fina

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Mundinger, Paul C., and David C. Lahti. "Quantitative integration of genetic factors in the learning and production of canary song." Proceedings of the Royal Society B: Biological Sciences 281, no. 1781 (2014): 20132631. http://dx.doi.org/10.1098/rspb.2013.2631.

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Learned bird song is influenced by inherited predispositions. The canary is a model system for the interaction of genes and learning on behaviour, especially because some strains have undergone artificial selection for song. In this study, roller canaries (bred for low-pitched songs) and border canaries (whose song is higher pitched, similar to the wild-type) were interbred and backcrossed to produce 58 males that sorted into seven genetically distinct groups. All males were tutored with the same set of songs, which included both low- and high-pitched syllables. Individuals were consistent wit

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Niu, Yu-Qiong, and Stephen G. Lisberger. "Sensory versus motor loci for integration of multiple motion signals in smooth pursuit eye movements and human motion perception." Journal of Neurophysiology 106, no. 2 (2011): 741–53. http://dx.doi.org/10.1152/jn.01025.2010.

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We have investigated how visual motion signals are integrated for smooth pursuit eye movements by measuring the initiation of pursuit in monkeys for pairs of moving stimuli of the same or differing luminance. The initiation of pursuit for pairs of stimuli of the same luminance could be accounted for as a vector average of the responses to the two stimuli singly. When stimuli comprised two superimposed patches of moving dot textures, the brighter stimulus suppressed the inputs from the dimmer stimulus, so that the initiation of pursuit became winner-take-all when the luminance ratio of the two

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Hupperets, P., and M. E. Van Hoef. "Combined modality treatment for breast cancer: Justification for integration of transplants at diagnosis." Journal of Clinical Oncology 24, no. 18_suppl (2006): 10760. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.10760.

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10760 >Introduction: In acute leukemia best therapy consist of fast remission-induction, consolidation of complete response and allogeneic transplantation to eradicate residual malignant cells. This therapeutic plan at diagnosis consists of three treatment combinations that have been proven to be most efficacious when administered consecutively according to protocol. Methods: The three treatment combinations were defined as independent entities and literature search was pursued to identify equivalent components for high risk and metastatic breast cancer. Results were tabulated. Results: Fir

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12

Ghattas, Mohammad, Antonio M. Mora, and Suhail Odeh. "A Novel Approach for Evaluating Web Page Performance Based on Machine Learning Algorithms and Optimization Algorithms." AI 6, no. 2 (2025): 19. https://doi.org/10.3390/ai6020019.

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This study introduces a novel evaluation framework for predicting web page performance, utilizing state-of-the-art machine learning algorithms to enhance the accuracy and efficiency of web quality assessment. We systematically identify and analyze 59 key attributes that influence website performance, derived from an extensive literature review spanning from 2010 to 2024. By integrating a comprehensive set of performance metrics—encompassing usability, accessibility, content relevance, visual appeal, and technical performance—our framework transcends traditional methods that often rely on limit

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Hengartner, Michael P. "The Evolutionary Life History Model of Externalizing Personality: Bridging Human and Animal Personality Science to Connect Ultimate and Proximate Mechanisms Underlying Aggressive Dominance, Hostility, and Impulsive Sensation Seeking." Review of General Psychology 21, no. 4 (2017): 330–53. http://dx.doi.org/10.1037/gpr0000127.

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The present work proposes an evolutionary model of externalizing personality that defines variation in this broad psychobiological phenotype resulting from genetic influences and a conditional adaptation to high-risk environments with high extrinsic morbidity-mortality. Due to shared selection pressure, externalizing personality is coadapted to fast life history strategies and maximizes inclusive fitness under adverse environmental conditions by governing the major trade-offs between reproductive versus somatic functions, current versus future reproduction, and mating versus parenting efforts.

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Wang, Yihua, Chen-Ching Yuan, Katarzyna Kazmierczak, Danuta Szczesna-Cordary, and Thomas P. Burghardt. "Single cardiac ventricular myosins are autonomous motors." Open Biology 8, no. 4 (2018): 170240. http://dx.doi.org/10.1098/rsob.170240.

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Myosin transduces ATP free energy into mechanical work in muscle. Cardiac muscle has dynamically wide-ranging power demands on the motor as the muscle changes modes in a heartbeat from relaxation, via auxotonic shortening, to isometric contraction. The cardiac power output modulation mechanism is explored in vitro by assessing single cardiac myosin step-size selection versus load. Transgenic mice express human ventricular essential light chain (ELC) in wild- type (WT), or hypertrophic cardiomyopathy-linked mutant forms, A57G or E143K, in a background of mouse α-cardiac myosin heavy chain. Ense

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Matrana, Marc Ryan, Patrick Mergler, Leo Posteraro, and James Lin Chen. "Changes in non-small cell lung cancer (NSCLC) next-generation sequencing (NGS) rates after electronic health record (EHR) integration using large-scale, multi-institutional, real-world data." Journal of Clinical Oncology 42, no. 16_suppl (2024): e13619-e13619. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.e13619.

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e13619 Background: NSCLC treatment guidelines recommend comprehensive NGS testing to detect genomic alterations and gene expression in key biomarkers that are relevant in diagnosis, therapy selection, prognosis, and clinical trials. While 70% of patients with NSCLC will have biomarker alterations related to therapeutic options, a large minority of patients still do not receive biomarker testing. Clinical workflow challenges outside the EHR ecosystem, like paper requisitions and faxed results, have been cited as barriers to adoption. To reduce sequencing barriers, Tempus deploys NGS through dir

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Barrera-Singaña, Carlos, María Paz Comech, and Hugo Arcos. "A Comprehensive Review on the Integration of Renewable Energy Through Advanced Planning and Optimization Techniques." Energies 18, no. 11 (2025): 2961. https://doi.org/10.3390/en18112961.

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The expanding integration of wind and photovoltaic (PV) energy is disrupting the power system planning processes. Their incorporation poses limitations to forecasting due to their inherent variability. This review compiles a total of ninety studies conducted and published between 2019 and 2025, presenting for the first time an integrated approach that simultaneously optimizes the generation, transmission, storage, and flexibility of resources given high ratios of renewable generation. We present a systematic taxonomy of conflicting optimization approaches—deterministic, stochastic, robust, and

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Seyfarth, Gregory M., and Benjamin Vollmayr-Lee. "Linear energy stable methods for an epitaxial growth model with slope selection." International Journal of Modern Physics C 29, no. 07 (2018): 1850059. http://dx.doi.org/10.1142/s0129183118500596.

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We consider a phase field model for molecular beam epitaxial growth with slope selection with the goal of determining linear energy stable time integration methods for the dynamics. Stable methods for this model have been found via a concave-convex splitting of the dynamics, but this approach generally leads to a nonlinear update equation. We seek a linear energy stable method to allow for simple and efficient time marching with fast Fourier transforms. Our approach is to parametrize a class of semi-implicit methods and perform unconditional von Neumann stability analysis to identify the regio

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18

Li, Hu. "Diversification Strategies for Suppliers in Small and Medium-Sized Manufacturing Enterprises: Pathway Selection and Performance Evaluation." Advances in Economics, Management and Political Sciences 190, no. 1 (2025): 181–89. https://doi.org/10.54254/2754-1169/2025.ld24933.

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Global supply chain fluctuations and geopolitical risks increasingly challenge small and medium-sized manufacturing enterprises (SMEs), particularly those with high supplier concentration and weak risk resilience. Drawing on resource dependence theory and industrial cluster theory, this study examines path selection and performance evaluation of supplier diversification strategies, employing case analysis to reveal the differential impacts of horizontal expansion and vertical integration on supply chain resilience in SMEs. Findings demonstrate that technology-collaborative diversification enha

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19

Ramalhete, Luís, Rúben Araújo, Miguel Bigotte Vieira, et al. "Integration of FTIR Spectroscopy and Machine Learning for Kidney Allograft Rejection: A Complementary Diagnostic Tool." Journal of Clinical Medicine 14, no. 3 (2025): 846. https://doi.org/10.3390/jcm14030846.

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Background: Kidney transplantation is a life-saving treatment for end-stage kidney disease, but allograft rejection remains a critical challenge, requiring accurate and timely diagnosis. The study aims to evaluate the integration of Fourier Transform Infrared (FTIR) spectroscopy and machine learning algorithms as a minimally invasive method to detect kidney allograft rejection and differentiate between T Cell-Mediated Rejection (TCMR) and Antibody-Mediated Rejection (AMR). Additionally, the goal is to discriminate these rejection types aiming to develop a reliable decision-making support tool.

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20

Recchia, Alessandra, Chiara Bonini, Zulma Magnani, et al. "Retroviral Vector Integration Deregulates Gene Expression but Has No Consequences on the Biology and Function of Transplanted T Cells." Blood 106, no. 11 (2005): 462. http://dx.doi.org/10.1182/blood.v106.11.462.462.

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Abstract Retroviral vectors have raised safety concerns for the genotoxic risk associated with their uncontrolled insertion into the human genome. The occurrence of T-cell leukemia in patients treated by gene therapy for X-SCID has been correlated with insertional activation of a T-cell proto-oncogene. However, no such event has been reported in other pre-clinical or clinical trials, suggesting the existence of disease- and/or transgene-specific risk factors in the X-SCID case. We have analyzed the integration pattern of a retroviral vector expressing a suicide gene (HSV-TK) and a surface mark

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Ellen, Jacob G., Etai Jacob, Nikos Nikolaou, and Natasha Markuzon. "Abstract 5373: Autoencoder-based multimodal prediction of survival for non-small cell lung cancer." Cancer Research 83, no. 7_Supplement (2023): 5373. http://dx.doi.org/10.1158/1538-7445.am2023-5373.

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Abstract Most non-small cell lung cancer (NSCLC) prognosis prediction approaches use one data type and do not take advantage of the large amount of multimodal data available. To evaluate and explore the benefits of multimodal data integration, we present a combined feature selection and denoising autoencoder pipeline for NSCLC survival prediction and survival subtype identification using microRNA (miRNA), mRNA, DNA methylation, long non-coding RNA (lncRNA) and clinical data. Survival performance for both lung adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC) patients was compared across

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Varela, Sebastian, Xuying Zheng, Joyce N. Njuguna, et al. "Deep Convolutional Neural Networks Exploit High-Spatial- and -Temporal-Resolution Aerial Imagery to Phenotype Key Traits in Miscanthus." Remote Sensing 14, no. 21 (2022): 5333. http://dx.doi.org/10.3390/rs14215333.

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Miscanthus is one of the most promising perennial crops for bioenergy production, with high yield potential and a low environmental footprint. The increasing interest in this crop requires accelerated selection and the development of new screening techniques. New analytical methods that are more accurate and less labor-intensive are needed to better characterize the effects of genetics and the environment on key traits under field conditions. We used persistent multispectral and photogrammetric UAV time-series imagery collected 10 times over the season, together with ground-truth data for thou

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23

Ganesh Bollina. "Transformative impact of salesforce CPQ: A cross-industry analysis." World Journal of Advanced Engineering Technology and Sciences 15, no. 3 (2025): 1410–17. https://doi.org/10.30574/wjaets.2025.15.3.1069.

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This article examines the implementation and impact of Salesforce Configure, Price, Quote (CPQ) solutions across diverse industries. Through analysis of five case studies spanning video telematics, healthcare equipment, technology, renewable energy, and Software as a Service sectors, this article identifies key patterns of transformation in sales processes, operational efficiency, and business outcomes. The article reveals critical success factors, including appropriate implementation partner selection, balanced customization versus standardization approaches, and thoughtful integration with e

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Quinn, Aleta. "Run the Experiment, Publish the Study, Close the Sale: Business, Values, Science and Biomedical Research – A Thematic Introduction." De Ethica 3, no. 2 (2016): 5–21. http://dx.doi.org/10.3384/de-ethica.2001-8819.16325.

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Business models for biomedical research prescribe decentralization due to market selection pressures. I argue that decentralized biomedical research does not match four normative philosophical models of the role of values in science. Non-epistemic values affect the internal stages of for-profit biomedical science. Publication planning, effected by Contract Research Organizations, inhibits mechanisms for transformative criticism. The structure of contracted research precludes attribution of responsibility for foreseeable harm resulting from methodological choices. The effectiveness of business

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Jang, Min Ho, Honggi Min, and Jae Seong Lee. "Enhancement of Transgene Expression by Mild Hypothermia Is Promoter Dependent in HEK293 Cells." Life 11, no. 9 (2021): 901. http://dx.doi.org/10.3390/life11090901.

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Mild hypothermia has been widely used to enhance transgene expression and improve the cellular productivity of mammalian cells. This study investigated mild hypothermia-responsive exogenous promoters in human embryonic kidney 293 (HEK293) cells using site-specific integration of various promoter sequences, including CMV, EF1α, SV40, and TK promoters, into the well-known genomic safe harbor site, AAVS1. EGFP expression driven by the CMV promoter increased up to 1.5-fold at 32 °C versus 37 °C under stable expression, while others showed no hypothermic response. Integration of short CMV variants

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Giannakaki, Aikaterini-Gavriela, Eftychia Papachatzopoulou, Ioannis Papapanagiotou, et al. "The Role of Exclusive Autologous Lipotransfer in Non-Irradiated Breasts After Mastectomy." Journal of Clinical Medicine 14, no. 13 (2025): 4468. https://doi.org/10.3390/jcm14134468.

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Background/Objectives: Autologous fat grafting (AFT) has become a widely used technique in breast reconstruction, offering natural aesthetics, tissue integration, and patient satisfaction. However, its clinical outcomes require comparison with implant-based reconstruction (IBR), the most common method in clinical practice. While AFT provides a more natural appearance and avoids foreign body-related complications, issues such as fat resorption, procedural variability, and oncological concerns necessitate further investigation. Additionally, artificial intelligence (AI) has been increasingly int

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Coxe, Tallon, and Rajeev K. Azad. "Silicon versus Superbug: Assessing Machine Learning’s Role in the Fight against Antimicrobial Resistance." Antibiotics 12, no. 11 (2023): 1604. http://dx.doi.org/10.3390/antibiotics12111604.

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In his 1945 Nobel Prize acceptance speech, Sir Alexander Fleming warned of antimicrobial resistance (AMR) if the necessary precautions were not taken diligently. As the growing threat of AMR continues to loom over humanity, we must look forward to alternative diagnostic tools and preventive measures to thwart looming economic collapse and untold mortality worldwide. The integration of machine learning (ML) methodologies within the framework of such tools/pipelines presents a promising avenue, offering unprecedented insights into the underlying mechanisms of resistance and enabling the developm

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Trofimova, Irina. "Functionality versus dimensionality in psychological taxonomies, and a puzzle of emotional valence." Philosophical Transactions of the Royal Society B: Biological Sciences 373, no. 1744 (2018): 20170167. http://dx.doi.org/10.1098/rstb.2017.0167.

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This paper applies evolutionary and functional constructivism approaches to the discussion of psychological taxonomies, as implemented in the neurochemical model Functional Ensemble of Temperament (FET). FET asserts that neurochemical systems developed in evolution to regulate functional-dynamical aspects of construction of actions: orientation, selection (integration), energetic maintenance, and management of automatic behavioural elements. As an example, the paper reviews the neurochemical mechanisms of interlocking between emotional dispositions and performance capacities. Research shows th

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Bouchair, Abderrahim, Belabbas Yagoubi, and Sid Ahmed Makhlouf. "A Driven Modern Portfolio Theory for Virtual Network Embedding in SDN-Enabled Cloud." Scalable Computing: Practice and Experience 23, no. 4 (2022): 421–39. http://dx.doi.org/10.12694/scpe.v23i4.2010.

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Network virtualization (NV) has evolved systematically through the urge to share computing resources and improve service deployment in a large-scale environment. Virtual network embedding (VNE) is a well-established technology applied to reinforce the NV process, providing a devoted implementation for a particular case study. In cloud computing, integration of software-defined networking (SDN) has proved to be a practical support to the principal cloud utilities. In return, the SDN-enabled cloud offers innovative deployment techniques for network-based services, which increase the opportunity

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Santana, S. E., and S. E. Lofgren. "Does nasal echolocation influence the modularity of the mammal skull?" Journal of Evolutionary Biology 26, no. 11 (2013): 2520–26. https://doi.org/10.5281/zenodo.13430988.

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(Uploaded by Plazi for the Bat Literature Project) In vertebrates, changes in cranial modularity can evolve rapidly in response to selection. However, mammals have apparently maintained their pattern of cranial integration throughout their evolutionary history and across tremendous morphological and ecological diversity. Here, we use phylogenetic, geometric morphometric and comparative analyses to test the hypothesis that the modularity of the mammalian skull has been remodelled in rhinolophid bats due to the novel and critical function of the nasal cavity in echolocation. We predicted that na

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Santana, S. E., and S. E. Lofgren. "Does nasal echolocation influence the modularity of the mammal skull?" Journal of Evolutionary Biology 26, no. 11 (2013): 2520–26. https://doi.org/10.5281/zenodo.13430988.

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(Uploaded by Plazi for the Bat Literature Project) In vertebrates, changes in cranial modularity can evolve rapidly in response to selection. However, mammals have apparently maintained their pattern of cranial integration throughout their evolutionary history and across tremendous morphological and ecological diversity. Here, we use phylogenetic, geometric morphometric and comparative analyses to test the hypothesis that the modularity of the mammalian skull has been remodelled in rhinolophid bats due to the novel and critical function of the nasal cavity in echolocation. We predicted that na

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Santana, S. E., and S. E. Lofgren. "Does nasal echolocation influence the modularity of the mammal skull?" Journal of Evolutionary Biology 26, no. 11 (2013): 2520–26. https://doi.org/10.5281/zenodo.13430988.

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(Uploaded by Plazi for the Bat Literature Project) In vertebrates, changes in cranial modularity can evolve rapidly in response to selection. However, mammals have apparently maintained their pattern of cranial integration throughout their evolutionary history and across tremendous morphological and ecological diversity. Here, we use phylogenetic, geometric morphometric and comparative analyses to test the hypothesis that the modularity of the mammalian skull has been remodelled in rhinolophid bats due to the novel and critical function of the nasal cavity in echolocation. We predicted that na

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Santana, S. E., and S. E. Lofgren. "Does nasal echolocation influence the modularity of the mammal skull?" Journal of Evolutionary Biology 26, no. 11 (2013): 2520–26. https://doi.org/10.5281/zenodo.13430988.

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(Uploaded by Plazi for the Bat Literature Project) In vertebrates, changes in cranial modularity can evolve rapidly in response to selection. However, mammals have apparently maintained their pattern of cranial integration throughout their evolutionary history and across tremendous morphological and ecological diversity. Here, we use phylogenetic, geometric morphometric and comparative analyses to test the hypothesis that the modularity of the mammalian skull has been remodelled in rhinolophid bats due to the novel and critical function of the nasal cavity in echolocation. We predicted that na

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Santana, S. E., and S. E. Lofgren. "Does nasal echolocation influence the modularity of the mammal skull?" Journal of Evolutionary Biology 26, no. 11 (2013): 2520–26. https://doi.org/10.5281/zenodo.13430988.

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(Uploaded by Plazi for the Bat Literature Project) In vertebrates, changes in cranial modularity can evolve rapidly in response to selection. However, mammals have apparently maintained their pattern of cranial integration throughout their evolutionary history and across tremendous morphological and ecological diversity. Here, we use phylogenetic, geometric morphometric and comparative analyses to test the hypothesis that the modularity of the mammalian skull has been remodelled in rhinolophid bats due to the novel and critical function of the nasal cavity in echolocation. We predicted that na

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Mujahidin, Muhamad, Rusfa, and Bunga Paramita. "Exposition Of Green Energy Development Integration In Mantang Village Area Bintan Regency." BIO Web of Conferences 70 (2023): 01006. http://dx.doi.org/10.1051/bioconf/20237001006.

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Green Energy from the perspective of energy processing and utilization is fundamental in sustainable regional expansion. This research gathered 12 hamlets in the coordinate area of Mantang Island in Bintan Regency as representatives for realizing the Lagrange and Laplace transform method used is determining utilization targets, regulations regarding the selection of types of energy sources and regulations regarding the use of technology in the form of indicators of extensive evolution. based on proportional accumulation of the observation area from 2020 to 2023, this research implements a form

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Schwarzwaelder, Kerstin, Manfred Schmidt, Annette Deichmann, et al. "The Clonal Inventory of Gene Corrected Hematopoiesis in Three Successful Clinical Gene Therapy Trials." Blood 110, no. 11 (2007): 3733. http://dx.doi.org/10.1182/blood.v110.11.3733.3733.

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Abstract To enhance the safety and efficacy of future gene therapy trials using integrating vector systems it is necessary to analyse the clonality of the genetically modified cell pool. The comparative analyses of integration site distribution and cellular gene expression will further reveal causal mechanisms of in vivo clone selection. We followed the repopulation clonality of 21 patients which participated in 3 successful clinical gene therapy trials via linear amplification mediated PCR (LAM PCR). We identified the integration sites (IS) of pre and post transplantation samples by Sanger se

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Wang, Yishen, and Beata Bajorek. "Selecting antithrombotic therapy for stroke prevention in atrial fibrillation: Health professionals’ feedback on a decision support tool." Health Informatics Journal 24, no. 3 (2016): 309–22. http://dx.doi.org/10.1177/1460458216675498.

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A Computerised Antithrombotic Risk Assessment Tool was developed for assisting the selection of antithrombotic therapy based on the risk versus benefit assessment. In view of the recent availability of the novel oral anticoagulants, this tool has been updated to CARATV2.0. To explore health professionals’ perspectives on the tool, semi-structured interviews were conducted in seven pharmacists, seven specialists, six general practitioners and six nurses, who were involved in management of antithrombotic therapy for atrial fibrillation. Three overarching themes emerged: (1) CARATV2.0 provides co

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El-Hageen, Hazem M., Ahmed Nabih Zaki Rashed, Hani Albalawi, et al. "Performance Signature of the Best Candidate-Graded Bandgap Materials for Solar Cells with Steady-State Conversion Efficiency." Energies 16, no. 19 (2023): 7001. http://dx.doi.org/10.3390/en16197001.

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This is a comprehensive research endeavor focused on enhancing the efficiency of the proposed solar cell design. The integration of the simulation techniques, judicious material selection, and meticulous performance metrics showcase a methodical approach toward creating a solar cell capable of achieving high efficiency across a wide spectrum of light in the AM 1.5 G1 sun solar cell illumination spectrum. Having said this, many researchers are still working on the efficiency potential—based on external radiative efficiency (ERE), open-circuit voltage loss, and fill factor loss—of high-efficienc

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Karoliya, Nikunjbhai Manilal. "Automotive Door Systems Evolution: From Conventional Hinges to Advanced Automated Mechanisms – A Comparative Technical Analysis." European Journal of Computer Science and Information Technology 13, no. 48 (2025): 188–202. https://doi.org/10.37745/ejcsit.2013/vol13n48188202.

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This article examines the evolution and engineering complexities of automotive door systems, from conventional hinged configurations to advanced automated mechanisms. The article analysis begins with the historical progression of door technologies, highlighting their dual role as functional components and brand differentiators. A comparative assessment of traditional versus specialized door systems reveals significant differences in component complexity, manufacturing processes, and market adoption across vehicle segments. The article further shows the multifaceted engineering challenges inher

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Ye, Hanlin, Huadong Guo, Dong Liang, Zhen Xu, Yin Jin, and Guang Liu. "On the Observational Solid Angle in Estimating the Moon-based Disk-integrated Earth Outgoing Longwave Radiation." Astronomical Journal 169, no. 3 (2025): 123. https://doi.org/10.3847/1538-3881/ada4b4.

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Abstract Equipping sensors on the lunar surface would enable the capture of Earth’s outgoing longwave radiation (OLR) from nearly an entire hemisphere. However, the Earth’s nonsphericity would profoundly impact the observational solid angle, thereby influencing the disk-integrated Earth OLR estimation. This study analyzes the impact of the Earth’s ellipsoidal shape on the OLR estimation by examining the effects of the observational solid angle. In particular, an expansion-series-based method is proposed for calculating the observational solid angle, avoiding complex numerical integration. Thre

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Garuffo, Luca, Alessandro Leoni, Roberto Gatta, and Simona Bernardi. "The Applications of Machine Learning in the Management of Patients Undergoing Stem Cell Transplantation: Are We Ready?" Cancers 17, no. 3 (2025): 395. https://doi.org/10.3390/cancers17030395.

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Hematopoietic stem cell transplantation (HSCT) is a life-saving therapy for hematologic malignancies, such as leukemia and lymphoma and other severe conditions but is associated with significant risks, including graft versus host disease (GVHD), relapse, and treatment-related mortality. The increasing complexity of clinical, genomic, and biomarker data has spurred interest in machine learning (ML), which has emerged as a transformative tool to enhance decision-making and optimize outcomes in HSCT. This review examines the applications of ML in HSCT, focusing on donor selection, conditioning re

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Koechlin, Etienne. "An evolutionary computational theory of prefrontal executive function in decision-making." Philosophical Transactions of the Royal Society B: Biological Sciences 369, no. 1655 (2014): 20130474. http://dx.doi.org/10.1098/rstb.2013.0474.

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The prefrontal cortex subserves executive control and decision-making, that is, the coordination and selection of thoughts and actions in the service of adaptive behaviour. We present here a computational theory describing the evolution of the prefrontal cortex from rodents to humans as gradually adding new inferential Bayesian capabilities for dealing with a computationally intractable decision problem: exploring and learning new behavioural strategies versus exploiting and adjusting previously learned ones through reinforcement learning (RL). We provide a principled account identifying three

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Panhuis, Tami M., Nathaniel L. Clark, and Willie J. Swanson. "Rapid evolution of reproductive proteins in abalone and Drosophila." Philosophical Transactions of the Royal Society B: Biological Sciences 361, no. 1466 (2006): 261–68. http://dx.doi.org/10.1098/rstb.2005.1793.

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Observations from different taxa, including plants, protozoa, insects and mammals, indicate that proteins involved in reproduction evolve rapidly. Several models of adaptive evolution have been proposed to explain this phenomenon, such as sexual conflict, sexual selection, self versus non-self recognition and pathogen resistance. Here we discuss the potential role of sexual conflict in the rapid evolution of reproductive genes in two different animal systems, abalone ( Haliotis ) and Drosophila . In abalone, we reveal how specific interacting sperm–egg proteins were identified and discuss this

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Sun, Luyi, Jinsong Chen, Shanxin Guo, Xinping Deng, and Yu Han. "Integration of Time Series Sentinel-1 and Sentinel-2 Imagery for Crop Type Mapping over Oasis Agricultural Areas." Remote Sensing 12, no. 1 (2020): 158. http://dx.doi.org/10.3390/rs12010158.

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Timely and accurate crop type mapping is a critical prerequisite for the estimation of water availability and environmental carrying capacity. This research proposed a method to integrate time series Sentinel-1 (S1) and Sentinel-2 (S2) data for crop type mapping over oasis agricultural areas through a case study in Northwest China. Previous studies using synthetic aperture radar (SAR) data alone often yield quite limited accuracy in crop type identification due to speckles. To improve the quality of SAR features, we adopted a statistically homogeneous pixel (SHP) distributed scatterer interfer

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Priyadharshini S, Kamalakannan M, Andrew Anbarason J P, Anitha A, and Ramana K. "Effects of Static Somatosensory Balance Training Versus Bosu Ball Training on Balance For Institutional Elderly Population." Indian Journal of Physiotherapy & Occupational Therapy - An International Journal 18 (January 21, 2024): 730–35. http://dx.doi.org/10.37506/m0qgrz60.

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Background: As individuals age, balance becomes a critical aspect of daily tasks, involving the integration ofsensory feedback for movement planning and execution. The aging process leads to gradual degeneration,increasing the risk of falls and associated mortality rates among seniors. Falls can result in debilitating injuries,signalling the onset of various health issues and potentially leading to a cycle of decline in physical function.Purpose: To compare the effectiveness of static somatosensory physical activity for the state of equilibrium andbosu ball sessions on elderly individuals. The

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Al-Atrash, Khaled. "Standard Operating Procedures (SOPs) for the Selection of Toxic Industrial Chemicals (TICs) handheld Detection Equipment for the United Arab Emirates Civil Defense Forces. Technologies Versus Operations Integration." Journal of Materials Science and Chemical Engineering 13, no. 03 (2025): 44–78. https://doi.org/10.4236/msce.2025.133004.

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Mishan, Ramkrishna, Xingang Fu, Chanakya Hingu, and Mohammed Ben-Idris. "Impacts of Inertia and Photovoltaic Integration on Existing and Proposed Power System Transient Stability Parameters." Energies 18, no. 11 (2025): 2915. https://doi.org/10.3390/en18112915.

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The integration of variable distributed energy sources (DERs) can reduce overall system inertia, potentially impacting the transient response of both conventional and renewable generators within electrical grids. Although transient stability indicators—for instance, the Critical Clearing Time (CCT), fault-induced short-circuit current ratios, and machine parameters, including subtransient–transient reactances and associated time constants—are influenced by total system inertia, their detailed evaluation remains insufficiently explored. These parameters provide standardized benchmarks for syste

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Sipos, László, Ákos Nyitrai, Géza Hitka, László Ferenc Friedrich, and Zoltán Kókai. "Sensory Panel Performance Evaluation—Comprehensive Review of Practical Approaches." Applied Sciences 11, no. 24 (2021): 11977. http://dx.doi.org/10.3390/app112411977.

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Sensory assessors determine the result of sensory analysis; therefore, investigation of panel performance is inevitable to obtain well-established results. In the last few decades, numerous publications examine the performance of both panelists and panels. The initial point of any panelist measures are the applied selection methods, which are chosen according to the purpose (general suitability or product-specific skills). A practical overview is given on the available solutions, methods, protocols and software relating to all major panelist and panel measure indices (agreement, discrimination

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Shahid, Shahab, Noman Saghir, Reyan Saghir, Quillan Young-Sing, and Benjamin H. Miranda. "WALANT: A Discussion of Indications, Impact, and Educational Requirements." Archives of Plastic Surgery 49, no. 04 (2022): 531–37. http://dx.doi.org/10.1055/s-0042-1748659.

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AbstractWide-awake, local anesthesia, no tourniquet (WALANT) is a technique that removes the requirement for operations to be performed with a tourniquet, general/regional anesthesia, sedation or an anesthetist. We reviewed the WALANT literature with respect to the diverse indications and impact of WALANT to discuss the importance of future surgical curriculum integration. With appropriate patient selection, WALANT may be used effectively in upper and lower limb surgery; it is also a useful option for patients who are unsuitable for general/regional anesthesia. There is a growing body of evide

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Yang, Zaixian, Ruo Lin, Jia Li, Siqi Yin, Ji Li, and Jian Yang. "Innovative Design and Practical Reflections on Teaching Ideological and Political Aspects of ‘Pharmacoeconomics’ in the Digital Era." PSU Medical Journal 4, no. 3 (2024): 111–21. https://doi.org/10.31584/psumj.2024266949.

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Objective: This study examines the innovative design and practical application of ideological and political (IP) teaching in the Pharmaceutical Economics course in a digitally evolving educational landscape. It seeks to effectively integrate IP education into the curriculum, enhance the synergy between disciplinary and IP education, and foster students’ holistic skills and social responsibility.Material and Methods: The research began with a literature review to identify the unique characteristics of the “Pharmaceutical Economics” course and the theoretical underpinnings of IP teaching in a di

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