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1

Svitailo, V. S., and M. D. Chemych. "INTEGRATIVE INDICATORS OF ENDOGENOUS INTOXICATION, INFLAMMATORY ACTIVITY, AND SPECIFIC REACTIVITY IN PATIENTS WITH COVID-19." Інфекційні хвороби, no. 3 (October 11, 2024): 21–27. http://dx.doi.org/10.11603/1681-2727.2024.3.14873.

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The aim of the study is to identify changes in blood laboratory parameters, integrative indicators of endogenous intoxication, inflammation, and specific reactivity in patients with coronavirus disease. Patients and methods. The study included 77 patients with COVID-19, taking into account the inclusion and exclusion criteria. The comparison group consisted of 68 practically healthy people of the corresponding age. Laboratory blood tests were performed, on the basis of which integrative indicators of endogenous intoxication, inflammation and specific reactivity were calculated. Results. The da
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2

Saienko, Oleksandr, and Mykola Chemych. "CHANGES IN INDICATORS OF ENDOGENOUS INTOXICATION, NONSPECIFIC REACTIVITY, AND INFLAMMATION CAUSED BY SARS-COV-2." Eastern Ukrainian Medical Journal 12, no. 2 (2024): 422–30. http://dx.doi.org/10.21272/eumj.2024;12(2):422-430.

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Introduction: Despite the fact that the entire scientific world is concerned about COVID-19, about 65 million people are living with Long COVID, suffering from general weakness, fatigue, cognitive dysfunction, and shortness of breath. This problem is global for humanity because of the decrease in the ability to work and mental activity of the population, which leads to economic losses. The problem remains open and requires further research. Materials and Methods: a total of 108 patients were examined and divided into three groups: group A – 31 patients with confirmed COVID-19, group B – 35 pat
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Chemych, Mykola, Anastasiia Cherkashyna, and Oksana Chemych. "FEATURES OF CHANGES IN INTEGRATIVE INDICATORS OF ENDOGENOUS INTOXICATION, REACTIVITY, INFLAMMATION ACTIVITY IN PATIENTS WITH CHRONIC VIRAL HEPATITIS AND CHRONIC RENAL FAILURE." Eastern Ukrainian Medical Journal 11, no. 4 (2023): 461–70. http://dx.doi.org/10.21272/eumj.2023;11(4):461-470.

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The aim: to study the peculiarities of changes in integrative indicators of endogenous intoxication, reactivity and activity of inflammation in patients with chronic viral hepatitis B and C, and with chronic renal failure undergoing hemodialysis. Materials and methods. 19 patients with chronic viral hepatitis B (HBV) and chronic viral hepatitis C (HCV) with chronic renal failure and patients with chronic kidney disease (KD) were examined. Comparison group included 40 healthy blood donors. Epidemiological, clinical and laboratory examination was performed. Indicators of endogenous intoxication,
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4

Dushina, T. S., S. N. Suplotov, S. M. Klyashev, and L. A. Suplotova. "Features of changes in nonspecific factors of immunological reactivity in obesity." Meditsinskiy sovet = Medical Council, no. 16 (November 1, 2024): 257–64. http://dx.doi.org/10.21518/ms2024-325.

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Introduction. The study of pathogenetic factors of obesity is an urgent task of modern medicine. The formation of obesity is characterized by changes in the activity of individual mechanisms of innate immunity. At the same time, the values of laboratory indicators that characterize them are often within the current boundaries of the reference values of laboratory indicators of the immunity of a healthy person. This complicates the pathogenetic assessment of the mechanisms of nonspecific immunological reactivity in obesity and determines the need for further study of the characteristics of nons
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5

Dychko, D. V., and O. A. Dychko. "GENERAL IMMUNOLOGICAL RESISTANCE OF THE ORGANISM OF YOUNG FUTSAL PLAYERS WHO ARE IN THE V CRITICAL PERIOD OF IMMUNE SYSTEM FORMATION." Scientific Journal of National Pedagogical Dragomanov University. Series 15. Scientific and pedagogical problems of physical culture (physical culture and sports), no. 4(190) (April 25, 2025): 33–36. https://doi.org/10.31392/udu-nc.series15.2025.04(190).06.

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The article is devoted to the study of the general immunological resistance of the body of male futsal athletes at the age range of 13-14 years, who are in the V critical period of the formation of the immune system in the process of training and those who do not play futsal. Research methods: The study involved young futsal players of the Futsal Academy of Uzhorod, at the age beetwen 13 and 14 years (13.53 ± 0.08 years), and a group of peers who do not play futsal (13.60 ± 0.08). The immune status of boys at the age from 13 to 14 years old who are futsal athletes, was determined based on the
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6

Shatyr, Y. A., I. V. Ulesikova, I. G. Mulik, S. V. Bulatetsky, and A. B. Mulik. "Development of phenotypical individualization of the person social activity criteria and indicators." I.P.Pavlov Russian Medical Biological Herald 25, no. 4 (2017): 521–37. http://dx.doi.org/10.23888/pavlovj20174521-537.

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Social activity being one of the main elements of organization of human vital activity, is characterized by systemic principle of formation and individuality of manifestations. Recognizing importance of the role of factors of social nature in development of social activity of an individual, one should agree that individual specialness of behavior largely depends on phenotypically determined psychophysiological and psychological features of an individual.
 Aim. The aim of research was to develop criteria and parameters of phenotypic individualization of social activity of a person.
 M
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7

Nazarov, N. O., Yu A. Shatyr, S. F. Popov, V. V. Yusupov, M. V. Postnova, and A. B. Mulik. "SYST E MI C MANIFESTATIONS OF FUNCTIONAL, PSYCHOPHYSIOLOGICAL AND PSYCHOLOGICAL RISK FACTORS FOR THE DEVELOPMENT OF CHEMICAL ADDICTIONS IN MEN AND WOMEN." Journal of Volgograd State Medical University 19, no. 3 (2022): 157–64. http://dx.doi.org/10.19163/1994-9480-2022-19-3-157-164.

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The aim of the work was to identify the links between indicators of functional and psychophysiological status with psychological characteristics that determine the risk of developing chemical addictions in men and women. The study was carried out with the participation of 309 people, 137 men and 172 women aged 18-30, students of state universities in Volgograd, Samara and Arkhangelsk. The level of consumption of legal psychoactive substances was assessed based on the results of a retrospective self-assessment by respondents of the frequency of alcohol intake and tobacco smoking experience. The
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8

Duda, Y. V. "Nonspecific reactivity of the rabbits organism when exposed to cysticercosis." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 21, no. 94 (2019): 132–35. http://dx.doi.org/10.32718/nvlvet9424.

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One of the actual rabbits breeding problem is the reduction of their resistance, which is caused by the spread of individual invasive diseases, especially cysticercosis, which is caused by the larval Cysticercus pisiformis stage of the mature cestode Taenia pisiformis. The study was conducted on 38 male rabbits age 3–4 months, weighing 3.5–4.0 kg of the Californian breed, selected by analogy. Animal were separated into two groups: healthy animals (control group) and sick animals (research group). After blood collection, slaughter was conducted and the presence of cysticercus cysts was visually
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9

Romaniuk, V. L., O. G. Rud, L. P. Goralskyi, O. O. Kyrylchuk, and B. V. Gutyj. "Thyroid activity and human physical and mental health: environmental and clinical aspects." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 26, no. 101 (2024): 277–83. https://doi.org/10.32718/nvlvet-a10143.

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Based on the results of theoretical and practical research, the article defines the ecological and clinical aspects of human physical and mental health in connection with the activity of the thyroid gland in normal and pathological conditions. In general, quantitative and qualitative indicators of health as a bio-psycho-social and morpho-functional phenomenon are closely related to humoral and nervous mechanisms of regulation, as well as the body's reactivity, taking into account age and gender characteristics. Special attention should be paid to studies on the influence of thyroid activity on
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10

Radsikhovskii, M., L. Goralskii, B. Borissevich, and O. Dyshkant. "Integral indexes of intoxication in caninae coronaviridae enteritis." Naukovij vìsnik veterinarnoï medicini, no. 2 (144) (December 24, 2018): 13–19. http://dx.doi.org/10.33245/2310-4902-2018-144-2-13-19.

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In this article to be spoken about indicators of action of coronaviridae on an organism of animals – qualitative and quan-titative characteristics of blood. These indicators change at many patological reactions and participate in ensuring nonspe-cific and specific resistance of an organism. With the help of the analysis of integral leukocyte indices based on the formula of blood reflecting the state of neurohumoral homeostasis and immunological reactivity of the organism, the violations were first discovered and established humoral and cellular links of the immune system, micro- and macrophage
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11

Karpenko, Elizaveta N., Alexey L. Kharlan, and Elena V. Zaitseva. "THE STATE OF NON-SPECIFIC RESISTANCE OF THE SMALL BAT (PIPISTRELLUS PYGMAEUS LEACH, 1825) UNDER ADVERSE ANTHROPOGENIC FACTORS." Siberian Journal of Life Sciences and Agriculture 15, no. 5 (2023): 11–26. http://dx.doi.org/10.12731/2658-6649-2023-15-5-923.

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At present, an important feature of the study of bats is their ability to carry pathogens of dangerous viruses, which is important for epidemiology when analyzing the spread of infectious diseases. Therefore, the study of the nonspecific immunity of bats will be able to suggest their morbidity and ability to endure diseases dangerous to humans. The purpose of the study is to consider the state of nonspecific resistance of the small bat (Pipistrellus pygmaeus Leach, 1825) under the conditions of unfavorable anthropogenic factors in the territory of the Bryansk region. The article presents the r
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12

Smolyakova, Raisa M., Helena А. Kozyreva, and Katsiaryna M. Shpadaruk. "HEMATOLOGICAL INTEGRATED INDICATORS IN ASSESSING THE CELLULAR REACTIVITY OF THE BODY IN COVID-19 CORONAVIRUS INFECTION." Journal of the Belarusian State University. Ecology., no. 1 (2021): 77–84. http://dx.doi.org/10.46646/2521-683x/2021-1-77-84.

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The article analyzes the disorders in homeostasis diagnosed during the development of acute viral infection SARS-CoV-2 in patients. Hematological changes in patients with coronavirus infection were characterized by the development of disintegration of humoral mechanisms of regulation with the initiation of a systemic inflammatory reaction with an increase in the leukocyte index of intoxication, activation of necrobiotic processes, an increase in the activity of macrophage-microphage nonspecific protection with a predominance of effector links of the immunological process. The development of im
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13

Gertman, Alexander Mikhailovich, and Dina Mratovna Maksimovich. "Integrative therapy of postpartum endometritis in first-calf heifers in the conditions of a biogeochemical province." Agrarian Scientific Journal, no. 8 (August 31, 2023): 59–65. http://dx.doi.org/10.28983/asj.y2023i8pp59-65.

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The research was carried out at the Sarafanovo farm, in Chebarkul district, Chelyabinsk region. We established that postpartum endometritis in first-calf heifers is widespread in biogeochemical provinces that contain an excess of nickel and iron. This pathology demonstrates distinct violations of organism’s functional state, accompanied by changes of blood values, a decrease in nonspecific defenses and an increase in peroxidation processes. The on-farm treatment routine makes a certain therapeutic effect, but does not fully ensure the restoration of the body systems, especially the regulation
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14

Sokolovskaya, Irina. "Features of Indicators of Blood General Clinical Analysis and the Summary Analysis of an Organism’s General Reactivity at Chronic Inflammatory Process." French-Ukrainian Journal of Chemistry 10, no. 1 (2022): 84–100. http://dx.doi.org/10.17721/fujcv10i1p84-100.

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Inflammatory diseases cause health disorders which result in a reduction of the population. That is why this medical problem is considered to be a very important one. The human immune system is responsible for protecting the body from infections of various origins, while inducing chronic inflammation (characterized by a long, often invisible course) which can result in proneness to recurrence, complications and resistance to therapy. The authors of the article analyzed and proved that there are immune status shifts in patients with chronic nonspecific inflammatory processes depending on the pa
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15

Zaitseva, I. P., V. N. Tsygan, and A. E. Kim. "Effect of intake of Vitrum vitamin-mineral complex in combination with adaptogens on immune status and physical work capacity in highly skilled student athletes." Sports medicine: research and practice 11, no. 1 (2021): 24–29. http://dx.doi.org/10.47529/2223-2524.2021.1.2.

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Purpose of the study: to study the effect of Vitrum in combination with adaptogens on immunological reactivity and physical performance in athletes under conditions of intense training.Materials and methods: 4 groups of athletes, 10 people in each, went through a cycle of intensive training according to a specially developed methodology. Group I took Vitrum, group II — Vitrum + Eleutherococcus extract, group III — Vitrum + ginseng tincture. Group IV — ascorbic acid and was used as a control. Blood for analysis was taken from the cubital vein before and after 28 days of drug administration. Ind
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16

Kydyrmoldina, А., B. Zhetpisbayev, A. Utegenova, et al. "CHANGE OF IMMUNOLOGICAL RESISTANCE AND BIOCHEMICAL PROCESSES IN PERIPHERAL BLOOD LYMPHOCYTES IN ACTION STRESS." BIOLOGICAL SCIENCES OF KAZAKHSTAN 4 (December 2021): 8–15. http://dx.doi.org/10.52301/1684-940x-2021-4-8-15.

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The aim of the study was to study changes in immunological reactivity and biochemical processes in peripheral blood lymphocytes in Pakistani students under the action of muscle stress. To achieve this goal, the states of the immune, lipid peroxidation and antioxidant systems and energy metabolism were studied in 30 students from South Asia under the influence of muscle stress. The state of cellular, humoral and nonspecific phagocytic immunity was determined in all students before and 1, 2 and 3 days after the stress of muscle load. The research results show that the state of the immune system
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17

do Carmo, José Leandro Pereira, Gliére Silmara Leite Soares, Lucas da Silva Vieira, and Daniela Oliveira. "Atrial Natriuretic Peptide and Cardiovascular Diseases in Dogs and Cats." World's Veterinary Journal 14, no. 3 (2024): 467–75. http://dx.doi.org/10.54203/scil.2024.wvj54.

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The term biomarker encompasses various biological indicators that objectively reflect a patient's medical status with precision and reproducibility. These indicators range from basic measurements like pulse and blood pressure to more intricate laboratory tests. Cardiac markers are crucial for accurate and prompt diagnosis of heart diseases in animals. Given the challenge of diagnosing cardiac diseases in small animals due to nonspecific clinical signs, cardiac markers provide quantitative indicators of biological processes. These markers include cardiac troponins for myocardial injury, natriur
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18

Dovydenkova, M. V. "Study of the resistance of cows with mastitis depending on the age of lactation." Agrarian science 354, no. 11-12 (2022): 27–31. http://dx.doi.org/10.32634/0869-8155-2021-354-11-12-27-31.

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Relevance. The breeding stock and young cattle in the conditions of industrial technology of animal husbandry experience an increased antigenic load, which leads to disturbances in the immune status and the development of inflammatory processes manifested by endometritis and mastitis, diarrheal and respiratory syndromes. It was relevant to conduct a comprehensive assessment of the immunological reactivity of the animal’s body according to the state of resistance in cattle with clinical and subclinical mastitis, depending on the age of lactation. As a result of complex studies, the specific and
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19

Rodionova, Olga G., Pavel G. Sakun, Elena A. Sheiko, et al. "Low doses of visible electromagnetic radiation activating endogenous nonspecific antitumor resistance in patients with cervical cancer." Journal of Clinical Oncology 40, no. 16_suppl (2022): e17506-e17506. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e17506.

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e17506 Background: Ionizing radiation inhibits the immunological reactivity of the body and the system of nonspecific antitumor resistance in patients with cervical cancer (CC). The purpose of this study was to activate the system of nonspecific antitumor resistance using visible electromagnetic radiation in CC patients receiving chemoradiotherapy. Methods: The study included 30 patients, mean age 61 years, with stage IIIb CC (T3bNxM0). The main group (n = 15) received standard chemoradiotherapy (CRT): irradiation of the primary focus 80 Gy, lymphatic paths 55 Gy, with radiomodification with c
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20

Yanovski, Alexander, Hyman Menduke, and Melissa G. Albertson. "Analysis by Gender and Visual Imagery Reactivity of Conventional and Imagery Rorschach." Perceptual and Motor Skills 80, no. 3_suppl (1995): 1319–40. http://dx.doi.org/10.2466/pms.1995.80.3c.1319.

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Examined here are the effects of gender and Visual Imagery Reactivity in 80 consecutively selected psychiatric outpatients. The participants were grouped by gender and by the amounts of responsiveness to preceding therapy work using imagery (Imagery Nonreactors and Reactors). In the group of Imagery Nonreactors were 13 men and 22 women, and in the Reactor group were 17 men and 28 women. Compared were the responses to standard Rorschach (Conventional condition) with visual associations to memory images of Rorschach inkblots (Imagery condition). Responses were scored using the Visual Imagery Rea
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21

Sokolenko, M. O. "NONSPECIFIC ANTIINFECTIVE PROTECTION IN PATIENTS WITH COVID-19 DEPENDING ON GENE POLYMORPHISM, DISEASE SEVERITY AND COMORBIDITY." Medical Science of Ukraine (MSU) 20, no. 3 (2024): 44–52. https://doi.org/10.32345/2664-4738.3.2024.06.

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Background. The level of antiinfective protection is important in the comprehensive assessment of the immune status of patients, the study of which will provide an opportunity to develop a high-quality set of therapeutic and preventive measures to improve the effectiveness of medical care for patients with COVID-19. Aim: to conduct a comprehensive analysis of the level of nonspecific antiinfective protection in patients with COVID-19 depending on the polymorphism of the genes TMPRSS2 (C-allele; rs12329760), FGB (G-allele; rs1800790) and eNOS (T-allele; rs2070744), the severity of the disease a
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22

GEIKO, Valentina, Zaza LEMONDZHAVA, and Mykola POSOKHOV. "FEATURES OF IMMUNOLOGICAL REACTIVITY OF PATIENTS WITH COMBAT TRAUMATIC BRAIN INJURY DEPENDING ON ITS TYPE AND CHRONICIT." Ukrains'kyi Visnyk Psykhonevrolohii, Volume 33, issue 1 (122), 2025 (April 1, 2025): 13–18. https://doi.org/10.36927/2079-0325-v33-is1-2025-2.

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Among modern studies of the participation of the immune system in the pathogenesis of traumatic brain injury (TBI) in military — veterans and combatants — the study of immunological mechanisms in the most acute and acute periods, which include the first hours, days and weeks after receiving combat TBI, prevails. In this regard, it is of particular relevance to determine the features of immunological reactivity due to traumatization of the nervous system in terms of the chronicity of the course of mild TBI, also taking into account the high motivation of combatants to return to the battlefield,
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23

Kozitsyna, A. I., L. Yu Karpenko, and A. A. Bakhta. "Leukocyte indices in dogs with acquired primary hypothyroidism." Russian Journal of Immunology 27, no. 3 (2024): 477–82. http://dx.doi.org/10.46235/1028-7221-16747-lii.

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According to global statistics, hypothyroidism in dogs is a widespread disease. However, due to certain difficulties in conducting laboratory diagnostics, as well as the cross-species specificity of such indicators as thyroid-stimulating hormone, thyroglobulin autoantibodies, prompt diagnosis and differentiation of hypothyroidism in dogs in the practice of a veterinarian is difficult. Thus, it is relevant to search for secondary auxiliary methods of diagnosis and detection of hypothyroidism in dogs based on a set of indicators and diagnostic coefficients-indices. Since hypothyroidism causes an
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24

Chayakova, Akerke, Marzhan Myrzakhanova, S. O. Rakhyzhanova та ін. "State of Immunological Reactivity of Rat’s Body after Exposure to Different Doses of γ-Radiation in a Long Period and their Offense of the 1st Generation". Open Access Macedonian Journal of Medical Sciences 9, A (2021): 1097–103. http://dx.doi.org/10.3889/oamjms.2021.7633.

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 BACKGROUND: Recently, the problem of changes in immunological reactivity has become important with the growth of immunodeficiency states of a different nature. [4]. High radiosensitivity of the immune system, its stability in time and the irreversibility of some post-radiation changes can contribute to the development of long-term effects of radiation [2,3,6]. One of the tasks of modern medicine and biology is to study the effect of chronic or fractionated ionizing effects on the body's immune system both in the early and late periods of irradiation and their 1st generation desc
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25

Makhnvea, Natalia V., Natalia I. Syuch, and Nina A. Kuznetsova. "Nonspecific adaptive reactions in outpatients of dermatovenereological profile." Russian Journal of Skin and Venereal Diseases 24, no. 6 (2022): 553–63. http://dx.doi.org/10.17816/dv100773.

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BACKGROUND: Changes in the morphological composition of the blood are among the most important criteria for diagnosing and predicting the course of diseases, allowing to assess the physiological state of the body. Calculated indices that can catch minimal changes in the indicators of the leukocyte blood formula in the early stages of the development of the pathological process make it possible to judge complex changes, sometimes imperceptible during the clinical examination of the patient. A well-known method characterizing the state of homeostasis is a method for assessing the state of homeos
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26

Chemych, Oksana M., Mykola D. Chemych, Anna A. Olefir, and Oleh B. Berest. "CLINICAL FEATURES OF THE HIV INFECTION COURSE AND THE DEPENDENCE OF CHANGES IN LABORATORY PARAMETERS ON THE CLINICAL STAGE AND ON THE CD4 LYMPHOCYTES LEVEL." Wiadomości Lekarskie 74, no. 5 (2021): 1189–95. http://dx.doi.org/10.36740/wlek202105126.

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The aim: Is to determine the features of the HIV infection and changes in indicators of endogenous intoxication and immunoreactivity depending on the clinical stage and the level of CD4 lymphocytes. Materials and methods: 72 HIV-patients were examined. Comparison group included 40 healthy blood donors. Clinical and laboratory examination was performed. Indicators of endogenous intoxication, nonspecific reactivity and inflammatory activity were calculated. Results:Main opportunistic infections were: oropharyngeal candidiasis; tuberculosis of different localization, more often pulmonary tubercul
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27

Mulik, A. B., V. V. Yusupov, N. O. Nazarov, I. V. Ulesikova, S. F. Popov, and Yu A. Shatyr. "PSYCHOPHYSICAL DISADAPTATION AS A FACTOROF INITIATION OF THE CONSUMPTION OF PSYCHOACTIVE SUBSTANCES IN THE STUDENT ENVIRONMENT." Journal of Volgograd State Medical University 19, no. 1 (2022): 33–39. http://dx.doi.org/10.19163/1994-9480-2022-19-1-33-39.

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The aim of the work was to determine the relationship between indicators of psychophysical maladjustment, individual functional status and consumption of psychoactive substances among students. The study involved 137 students of state universities in Arkhangelsk. Identification of the experience of using psychoactive substances was carried out using questionnaire and blank methods of retrospective self-assessment of the study participants. Determination of psychophysical maladaptation was carried out on the basis of a combination of psychological and psychosomatic symptoms of stress reactions
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28

Zaporozhets, Tetiana, and Oleksandr Sanyk. "Overweight and dysregulation of the autonomic nervous system in young persons." NaUKMA Research Papers. Biology and Ecology 6 (August 3, 2023): 33–40. http://dx.doi.org/10.18523/2617-4529.2023.6.33-40.

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Background. More than 1 billion people worldwide are obese, and this number is growing. Obesity at an early age is accompanied by impaired carbohydrate tolerance and the development of type 2 diabetes, lipid metabolism pathology, obstructive apnea, hypercoagulability, chronic inflammation and the development of insulin resistance in the future. In modern literature, there is no single point of view regarding the role of the autonomic nervous system in the coordination of hormonal, nervous and metabolic factors in the body.Aim. The article presents the results of studying the functional state o
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29

Vadzyuk, Stepan, and Roman Shmatа. "NEURYDYNAMIC FEATURES OF YOUNG PEOPLE WITH DIFFERENT DURATION OF VESTIBULAR ILLUSION." EUREKA: Life Sciences 6 (November 30, 2019): 57–62. http://dx.doi.org/10.21303/2504-5695.2019.001062.

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The article deals with neurodynamic features in persons with different duration of vestibular illusion of rotation. The review of the literature concludes that the time of arbitrary reactions is ensured by a high level of integrative activity of nerve formations. Also, data on the effect of rotation test on the indicators of vestibulo-sensory reactions of young fighters-all-rounders and on the sensorimotor reactivity and success of flight training are given. The study of sensorimotor reactions revealed that the longest latency periods were in the people with very long vestibular illusion again
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30

Stepan, Vadzyuk, and Shmatа Roman. "NEURYDYNAMIC FEATURES OF YOUNG PEOPLE WITH DIFFERENT DURATION OF VESTIBULAR ILLUSION." EUREKA: Life Sciences 6 (February 7, 2020): 57–62. https://doi.org/10.21303/2504-5695.2019.001062.

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The article deals with neurodynamic features in persons with different duration of vestibular illusion of rotation. The review of the literature concludes that the time of arbitrary reactions is ensured by a high level of integrative activity of nerve formations. Also, data on the effect of rotation test on the indicators of vestibulo-sensory reactions of young fighters-all-rounders and on the sensorimotor reactivity and success of flight training are given. The study of sensorimotor reactions revealed that the longest latency periods were in the people with very long vestibular illusion again
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31

Поспелова, Olga Pospelova, Соловьева, et al. "INFLUENCE OF SANATORIUM TREATMENT WITH THERMOTHERAPY ON THE ADAPTIVE CAPACITY OF HARD-WORKING PEOPLE." Бюллетень Восточно-Сибирского научного центра Сибирского отделения Российской академии медицинских наук 1, no. 3 (2016): 20–23. http://dx.doi.org/10.12737/21588.

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370 apparently healthy men aged 27 to 35 with considerable mental and physical burden were examined at the sanatorium.
 They were divided into two groups depending on the duration of rehabilitation. Group 1 consisted of 226
 men with rehabilitation period from 18 to 21 days. Group 2 comprised 144 men with rehabilitation period from 10 to
 14 days. Each group was subdivided into three subgroups: A, B and C. Patients of Group 1 subgroup A visited cryochamber,
 patients of Group 1 subgroup B visited infrared sauna, and patients of Group 1 subgroup C visited vibration sauna&#x0
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32

Колоскова, Е. К., Л. А. Иванова, С. И. Тарнавская, et al. "Indicators of Nonspecific Bronchial Hyperresponsiveness in Children with Asthma Depending on Inflammatory Blood Patterns." Педиатрия. Восточная Европа, no. 2 (June 8, 2022): 226–33. http://dx.doi.org/10.34883/pi.2022.10.2.005.

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Введение. Достижение контроля над бронхиальной астмой у детей является основой стратегии лечения этого социально значимого заболевания. Чрезвычайно важной задачей является необходимость проведения мониторинга бронхиального воспаления для уменьшения частоты и степени тяжести обострений.Цель. С целью оптимизации комплексного лечения детей, больных бронхиальной астмой, ретроспективно исследовать показатели неспецифической реактивности бронхов в зависимости от воспалительных паттернов крови.Материалы и методы. Для достижения поставленных целей проведено комплексное клинико-иммунологическое обследо
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Matviiuk, O. Ya. "DYNAMICS OF HEMATOLOGICAL PARAMETERS OF ENDOGENOUS INTOXICATION IN ADULT PATIENTS WITH MEASLES WITH DIFFERENT SEVERITY OF THE DISEASE." Bukovinian Medical Herald 28, no. 4 (112) (2024): 53–60. https://doi.org/10.24061/2413-0737.28.4.112.2024.9.

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Introduction. Measles is a highly contagious infectious disease with upper respiratory tract catarrh, conjunctivitis, stage exanthema and pronounced syndrome of endogenous intoxication.Aim. To determine the degree of endogenous intoxication syndrome in adult patients with measles and make a connection with the severity of the underlying disease.Materials and methods. There were observed 120 adult patients with measles. The diagnosis was confirmed by epidemiological, clinical and laboratory criteria, using the Android-application the integrative indicators of endogenous intoxication and immunor
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Chernuskyi, Viacheslav, Mykola Popov, Hanna Letiaho, Olha Hovalenkova, Svitlana Tolmachova, and Alisa Popova. "Functional condition of the sensitized T-lymphocytes according to RBTL in children with non-rheumatic myocarditis." 8, no. 8 (December 29, 2021): 98–103. http://dx.doi.org/10.26565/2617-409x-2021-8-10.

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Summary. The increased proportion of non-rheumatic myocarditis in children has recently determined the urgency of this problem in pediatrics. It is known that non-rheumatic myocarditis in children often occurs against the background of viral or bacterial infection under conditions of altered reactivity of the immune system. There is evidence, mainly in rheumatism, that spontaneous and stimulated lymphocyte blatransformation response in such patients reflects the activity of the process, its tendency to chronicity and may serve as a criterion for the adequacy of therapy. Studies on the function
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Semenov, V. G., E. P. Simurzina, S. G. Kondruchina, et al. "Influence of biopreparations on the postnatal period of highly productive cows." IOP Conference Series: Earth and Environmental Science 935, no. 1 (2021): 012041. http://dx.doi.org/10.1088/1755-1315/935/1/012041.

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Abstract The article describes the results of comparative studies on the influence of new immunostimulants on the course of postnatal recovery of the cows under conditions of intensive milk production technology. Injections of PS-2 (group 1) and Prevention-N-E (group 2) at a dose of 10 ml forty, twenty and ten days before calving, and a injection of PDE at a dose of 20 ml with E-Selenium of 10 ml (group 3) twenty days before calving prevent the occurrence of obstetric and gynecological pathology, improve reproductive qualities, as compared to the control group, where no biologicals were inject
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Omelian, L. P., and N. A. Matsehora. "Hematological and biochemical features with tuberculosis and bacterial lymphadenitis in children." Tuberculosis, Lung Diseases, HIV Infection, no. 3 (October 1, 2021): 15–21. http://dx.doi.org/10.30978/tb2021-3-15.

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Objective — to improve approaches to differential diagnosis of lymphadenitis by identifying features of hematological and biochemical parameters of blood of children with nonspecific bacterial and specific tuberculous lymphadenitis.
 Materials and methods. Under our supervision were 45 children aged 1 to 5 years with an increase in lymph nodes (LN), who were treated in the surgical department of the Odessa Regional Children’s Clinical Hospital for the period from 2017 to 2018. Patients were assessed for general condition and affected lymph node lesions, as well as blood sampling for gener
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Sokolovskaya, Irina, Nataliia Prybora, Valentyna Nechyporenko, et al. "Assessment of the Nature of Dyslipoproteinemias and Correlations of Indicators of General Reactivity and Lipid Metabolism in Patients with Chronic Nonspecific Inflammation of the Reproductive System." French-Ukrainian Journal of Chemistry 11, no. 2 (2023): 77–94. http://dx.doi.org/10.17721/fujcv11i2p77-94.

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Metabolic disorders can occur at all levels of biological organization - from molecular and cellular to the level of the organism as a whole. These changes may result from disruptions in hormonal mechanisms, actions of pathogenic factors, or infections. Primary metabolic disorders are the basis of many diseases, such as diabetes, obesity, and atherosclerosis, while secondary disorders accompany most pathological processes. Disruption of lipid metabolism leads to changes in their functions and the development of pathological processes, such as dyslipoproteinemia, and also contributes to the dev
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Sumtsova, Kateryna, Vladyslav Berezhok, Anastasiia Lishnevska, and Mykola Chemych. "THE DEPENDENCE OF CHANGES IN LABORATORY INDICATORS ON ACCOMPANYING PATHOLOGY IN PATIENTS WITH VIRAL HEPATITIS C." Eastern Ukrainian Medical Journal 12, no. 1 (2024): 69–80. http://dx.doi.org/10.21272/eumj.2024;12(1):69-80.

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Objective: to determine the dependence of changes in hematological, biochemical indicators and indexes of nonspecific reactivity, inflammation, endogenous intoxication on accompanying pathology in patients with chronic viral hepatitis C (HCV). Materials and methods: hematological, biochemical, non-specific immunological changes were analyzed in 20 chronic HCV patients without cardiovascular system pathologies, in 20 chronic HCV patients with concomitant coronary heart disease (CHD), in 20 people with coronary heart disease and arterial hypertension, and in 40 healthy people. Statistical analys
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Darenskaya, Marina A., E. D. Kazantseva, A. G. Petrova, et al. "Influenza and non-influenza ARVI in children. A relationship between cytokine profile, parameters of the “lipid peroxidation – antioxidant defense system” as well as clinical and laboratory indicators." Russian Journal of Infection and Immunity 14, no. 4 (2024): 719–30. http://dx.doi.org/10.15789/2220-7619-ian-17573.

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Influenza and acute respiratory viral infections (ARVI) impose a substantial damage to the population health in the Russian Federation due to their seasonal circulation and predominantly affect young children. A very few data on the cytokine profile, the nonspecific LPO — AOD system and their relationships with clinical characteristics in such diseases in preschool children are available. The aim of this study was to assess the cytokine profile, LPO — AOD system parameters and their relationship with the clinical and laboratory characteristics of diseases in preschool children with influenza a
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Mashchenko, Serhii, Oleksandr Stoianov, Valerii Kalashnikov, Ruslan Vastianov, Tamara Andreyeva, and Svitlana Oliinyk. "Vegetative and cerebrovascular regulation in vestibular dysfunctions of ischemic origin." Ukrains'kyi Visnyk Psykhonevrolohii, Volume 30, issue 4 (113), 2022 (December 27, 2022): 12–17. http://dx.doi.org/10.36927/2079-0325-v30-is4-2022-2.

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Vestibular dysfunction (VD) is a common syndrome of ischemic brain damage that occurs with pronounced vegetative accompaniment, cerebrovascular regulation disorder. 62 patients with VD on the background of chronic brain ischemia in the compensated (I group n = 24) and subcompensated (II group n = 38) stages were examined (40.3 % men; 59.7 % women), age from 18 to 55 years, average age was 38.6 ± 1.6 years. In case of ischemic damage to the brain due to degenerative-dystrophic changes in the cerebral cortex, certain mechanisms of the development of VD with dizziness have been registered. Their
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Rychkova, Lyubov V., Marina A. Darenskaya, Alla G. Petrova, et al. "A relation between specific immune status indicators and activity of “lipid peroxidation — antioxidant defense” system in COVID-19 neonates." Russian Journal of Infection and Immunity 13, no. 3 (2023): 497–505. http://dx.doi.org/10.15789/2220-7619-arb-8057.

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The 2019 coronavirus infection (COVID-19) has not been considered as a solved issue for public health. Pregnant women and newborns are specifically vulnerable to COVID-19 infection compared to older children and healthy young adults. Virtually no data on relation between diverse arms of immunity in patients in neonatal period and coronavirus infection are available. The obtained results can contribute to a better understanding of the pathogenetic mechanisms on reactivity of immune processes in young patients and corresponding formation of approaches for prevention and correction of such disord
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Illek, Ya Yu, I. G. Suetina, N. V. Khlebnikova, E. V. Suslova, and A. V. Galanina. "Effectiveness of complex treatment associated with ozone therapy on clinical indicators and immunity status in children with atopic dermatitis and concomitant allergic rhinitis." Perm Medical Journal 39, no. 4 (2022): 85–96. http://dx.doi.org/10.17816/pmj39485-96.

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Objective. To evaluate the effectiveness of complex treatment in combination with ozone therapy in children with moderate atopic dermatitis and concomitant moderate persistent allergic rhinitis.
 Materials and methods. Under observation were children of preschool and primary school age with moderate atopic dermatitis and concomitant moderate persistent allergic rhinitis. In these children, we studied clinical indicators, the content of populations and subpopulations of lymphocytes in the blood, immunoglobulins and circulating immune complexes in the blood serum, phagocytosis indicators, e
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Zhukova, G. V., E. M. Frantsiyants, A. I. Shikhlyarova, et al. "Features of blood parameters and adaptational status of Balb/c and C57Bl/6 mice lines in the absence of special influences." South Russian Journal of Cancer 4, no. 4 (2023): 44–56. http://dx.doi.org/10.37748/2686-9039-2023-4-4-5.

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Purpose of the study. A comparative analysis of blood parameters and some characteristics of the adaptation status of intact Balb/c and C57Bl/6 mice of both sexes.Materials and methods. We investigated intact mice of both sexes belonging to the C57Bl/6 (n = 18) and Balb/c (n = 20) lines. The age characteristics of these animals corresponded to the first half of the reproductive period. We studied the parameters of the complete and biochemical blood tests, the weight characteristics of the thymus, spleen and adrenal glands. The character and tension of general nonspecific adaptational reactions
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Eremushkin, M. A., E. V. Gameeva, A. M. Stepanova, and N. S. Prilipko. "Effectiveness of vibration-mechanical massage in medical rehabilitation programs." Journal of Medical Rehabilitation 2, no. 4 (2025): 327–35. https://doi.org/10.17749/2949-5873/rehabil.2024.32.

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Background. The combination of various physical factors in the treatment of one nosology can elicit new integrative effects and enhance treatment efficacy. The study evaluates effectiveness of vibration-mechanical massage (VMМ) in patients with various nosological diseases. Methods of hardware VMМ have firmly entered the field of aesthetic medicine and cosmetology. The recent rapid development of VMМ technologies stimulates research and development work to study their effectiveness.Objective: To evaluate the possibility of using VMМ in comprehensive postoperative rehabilitation programs.Materi
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Adamovskaya, O. N., I. V. Ermakova, and S. B. Dogadkina. "Features of neurovegetative and humoral regulation of cognitive activity in adolescents when using electronic devices." Acta Biomedica Scientifica 9, no. 1 (2024): 85–95. http://dx.doi.org/10.29413/abs.2024-9.1.9.

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Background. Studying the functional state of the body of adolescents when they preform cognitive activity using electronic devices is of great importance due to the introduction of information and computer technologies into the educational process. Identifying the characteristics of the reactivity of students’ bodies when performing cognitive activities in a digital environment will contribute to both optimization of learning and health protection.The aim. To study the autonomic regulation of heart rate, electrodermal activity, cerebral circulation and the level of cortisol in saliva when adol
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Kostyk, O. P., K. I. Volnytska, O. Ja Vytryhovskyj, and N. D. Rudnytska. "Bronchial obstruction syndrome in patients with tuberculosis of lung: current state of the actual problem." Acta Medica Leopoliensia 26, no. 2-3 (2020): 94–100. http://dx.doi.org/10.25040/aml2020.02-03.094.

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A review of modern scientific literature is presented ; features of pathogenesis, diagnosis and clinical course of bronchial obstruction syndrome in patients with pulmonary tuberculosis are studied. Aim. To analyze literature sources, which cover modern views on the pathogenesis, features of clinical manifestation and diagnostics in patients with tuberculosis of the lungs with bronchial obstruction syndrome for verification of its origin. Materials and Methods. A review of scientific publications and a generalization of literature data for the period from 2009 to 2019 were conducted. Thirty-si
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Пришляк, А. Я., О. Я. Матвиюк, and А. П. Бойчук. "Evaluation of Endogenous Intoxication in Adult Patients with Measles of Varying Severity and their Coherence with the Development of Complications at an Early Stage of the Disease." Клиническая инфектология и паразитология, no. 3 (November 24, 2020): 270–81. http://dx.doi.org/10.34883/pi.2020.9.3.027.

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Введение. Корь – высококонтагиозное инфекционное заболевание с выраженным синдромом эндогенной интоксикации.Цель. Определить степень синдрома эндогенной интоксикации у взрослых пациентов с корью и оценить способность организма к эффективной иммунологической реакции.Материалы и методы. Наблюдали 465 взрослых пациентов с корью. Диагноз подтверждали по эпидемиологическим, клиническим и лабораторным критериям, в Android-приложении рассчитывали интегративные показатели эндогенной интоксикации и иммунореактивности организма.Результаты и обсуждение. Среди обследованных было 247 женщин (53,12%) и 218
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Kovalchuk, T. A., and N. Yu Luchyshyn. "The features of autonomic nervous system homeostasis and adaptive potential in children with syncope." Modern pediatrics. Ukraine, no. 3(115) (April 27, 2021): 5–14. http://dx.doi.org/10.15574/sp.2021.115.5.

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The investigation of the nature of syncope shows that it is caused by failure of compensatory reflex mechanisms of the autonomic nervous system. Therefore, the determination of specific parameters of autonomic nervous system homeostasis and adaptive potential improves the approach to determining the clinical predictors of the syncope and facilitate its early diagnosis. Purpose — to determine the nature and compare of autonomic dysregulation and functional changes of in children with syncope of different genesis, to identify the circumstances for the formation of insufficient autonomic regulati
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Khomyshyn, V. P., A. O. Solomonko, O. O. Novytskyy, and O. B. Romaniuk. "Risk of occurence and prophylaxis of bronchospasm in representatives of athletic kinds of sports." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 20, no. 91 (2018): 92–96. http://dx.doi.org/10.32718/nvlvet9119.

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The problem of bronchospasm caused by physical activity is relevant both, in the sport of high achievements and for those who lead an active way of life. The high prevalence of BFL in the sport of high achievements is due to intense physical activity, the influence of climatic factors and the conditions of the training process. However, athletes who regularly do sports and have BFL, experience symptoms of obstruction all the time. Moreover, physical activity can provoke inflammation of the respiratory tract with the synthesis of cysteine leukotrienes, leukocytic infiltration of the mucosa and
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Чиркова, Н. В., Ж. В. Вечеркина, Н. А. Шалимова, Е. А. Лещева, С. Г. Шелковникова, and Д. А. Голубцов. "THE RESULTS OF THE STUDY OF THE INDICATORS OF LOCAL IMMUNITY IN PATIENTS WITH REMOVABLE PROSTHESES AGAINST THE BACKGROUND OF THE APPLICATION OF THE DEVELOPED PROGRAM FOR THE PREVENTION OF ORAL DYSBIOSIS." СИСТЕМНЫЙ АНАЛИЗ И УПРАВЛЕНИЕ В БИОМЕДИЦИНСКИХ СИСТЕМАХ 22, no. 3 (2023): 52–58. http://dx.doi.org/10.36622/vstu.2023.22.3.007.

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В основе развития реакций тканей протезного поля лежат различные патогенетические механизмы, обусловленные свойствами материалов, из которых изготовлен протез, способами его фиксации, характером передачи жевательного давления, величиной базиса протеза. Ответные реакции протезного ложа определяются с одной стороны, характером, интенсивностью и продолжительностью действия раздражителя, а с другой – реактивностью организма. Большое значение в современной стоматологии уделяется изучению нормальной микрофлоры человека, так как доказано ее участие в процессах пищеварения, обмене веществ, синтезе вит
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