Academic literature on the topic 'Integrin LFA-1'

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Dissertations / Theses on the topic "Integrin LFA-1"

1

Stewart, Mairi Purslow. "Activation of the leukocyte integrin LFA-1 lymphocytes." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321666.

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2

McDowall, Alison Jane. "Mechanisms of activation of the leukocyte integrin LFA-1." Thesis, Open University, 2000. http://oro.open.ac.uk/58066/.

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This work was undertaken to characterise the interaction of the leukocyterestricted integrin LFA-1 (CD1la/CD18) with its ligands. LFA-1 function is critical for an immune response and, for example, allows leukocyte binding and transmigration across the endothelium, antigen presentation and cytotoxic T lymphocyte-mediated killing. The ligands for LFA-1 are the Intercellular Adhesion Molecules (ICAMs), with ICAM-1, ICAM-2 and ICAM-3 being the best characterised. The binding sites on ICAM-1 and ICAM-3 for LFA-1 were investigated with the use of antibodies and mutated proteins. The following regio
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3

Stanley, Paula E. "The interaction between integrin LFA-1 and its ligand ICAM-1." Thesis, Open University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340738.

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4

Hedman, Håkan. "Regulation of leukocyte integrin adhesiveness." Doctoral thesis, Umeå universitet, Molekylärbiologi (Teknat- och Medfak), 1995. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100597.

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5

Parks, William. "Force activation of I domain containing and lacking integrins on live cells." Thesis, Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/42695.

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Cellular adhesion plays a crucial role in the biological function of cells, allowing them to communicate and signal, as well as physically anchor, by enabling them to adhere to either other cells or the extra cellular matrix (ECM). This process is regulated by several factors including intrinsic bond kinetics, internal cellular signaling, environment, force exerted on the bond, and force history of the bond. Concerning the force and force history dependence, the observation of catch bonds in integrin binding has asked as more questions than it has answered. To explore the force and force hist
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6

Geginat, Jens. "Interdependence between adhesion and proliferation the role of the [alpha]L- [alphaL-], [beta]2-integrin [beta2-integrin] (LFA-1) in t cell antigen receptor dependent proliferation of primary human t lymphocytes /." [S.l.] : [s.n.], 1999. http://www.diss.fu-berlin.de/1999/35/index.html.

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7

Sirim, Pinar. "Funktionelle Charakterisierung der Signaltransduktionskaskade des LFA-1-Integrins." Diss., lmu, 2001. http://nbn-resolving.de/urn:nbn:de:bvb:19-3716.

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Lam, Hang-yee Chloe, and 林倖而. "Identification of interacting partners of LFA-1 in the testis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/202255.

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Sweeney, Bernadette Mary. "Activation of LFA-1 through mutations within the IDAS site of the I Domain : their effects on ligand binding and the capacity of LFA-1 to signal to other integrins." Thesis, Open University, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402826.

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Birkigt, Jessica [Verfasser], Eugen [Gutachter] Feist, and Ulrike [Gutachter] Seifert. "Die Rolle von SLP-76 bei der T-Zellrezeptor-vermittelten Aktivierung des Integrins LFA-1 in T-Zellen / Jessica Birkigt ; Gutachter: Eugen Feist, Ulrike Seifert." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2020. http://d-nb.info/1223615677/34.

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