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Dissertations / Theses on the topic 'Intensity modulated radiotherapy'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Cufflin, Rebecca Sian. "Verification of Intensity Modulated Radiotherapy." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/25873/.

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The main aim of this work was to develop accurate and efficient methods for the verification of Intensity Modulated Radiotherapy (IMRT). IMRT is an advanced form of radiotherapy demanding extensive verification procedures to ensure treatments are delivered accurately. This requires comprehensive sampling of the complex dose distributions impacting on the tumour volume and radiationsensitive ‘organs at risk’. This work has focused on the use of electronic portal imaging devices (EPIDs) for verification purposes. Modern EPIDs are composed of a scintillator and an amorphous silicon detector panel

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2

Bär, Werner. "Optimized delivery of intensity modulated radiotherapy." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965610934.

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3

Khadija, Murshed. "A clinical comparison and analysis between conventional MLC based and solid compensator based IMRT treatment techniques [electronic resource] /." Toledo, Ohio : University of Toledo, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=mco1264434257.

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Thesis (M.S.)--University of Toledo, 2009.<br>"In partial fulfillment of the requirements for the degree of Master of Science in Biomedical Sciences." Title from title page of PDF document. Bibliography: p. 34-35.

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4

Seco, Joao Carlos. "Comparison of the efficacy of intensity modulated radiotherapy." Thesis, Institute of Cancer Research (University Of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398937.

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5

Glendinning, Andrew D. "Studies of the dosimetric verification of intensity modulated radiotherapy." Thesis, University of Leicester, 2001. http://hdl.handle.net/2381/29383.

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The ability to verify absorbed dose distributions produced by intensity modulated radiotherapy (IMRT) using dynamic multileaf collimation is of great concern in the clinical application of this technique. This thesis investigates two approaches using an Elekta SL/ linear accelerator operating in dynamic mode (Elekta Oncology Systems, Crawley, UK). A novel strip ionisation chamber array, located at the beam aperture, was designed and used in conjunction with a specialised electrometer. This also recorded cumulative accelerator monitor units (MU) via an isolated interface to the accelerator. The

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6

Williams, Matthew John Physics Faculty of Science UNSW. "Investigations into static multileaf collimator based intensity modulated radiotherapy." Awarded by:University of New South Wales. Physics, 2005. http://handle.unsw.edu.au/1959.4/20577.

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Intensity Modulated Radiation Therapy (IMRT) is a modern radiotherapy treatment technique used to obtain highly conformal dose distributions. The delivery of IMRT is commonly achieved through the use of a multileaf collimator (MLC). One of the hindrances at present to the widespread use of IMRT is the increased time required for its planning, delivery and verification. In this thesis one particular method of MLC based IMRT, known as Static Multileaf Collimator based IMRT (SMLC-IMRT), has been studied along with methods for improving it???s delivery efficiency. The properties of an MLC comm

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7

Markovic, Miljenko. "Comparison of IMRT delivery methods a thesis /." San Antonio : UTHSC, 2008. http://learningobjects.library.uthscsa.edu/cdm4/item_viewer.php?CISOROOT=/theses&CISOPTR=58&CISOBOX=1&REC=13.

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8

Taylor, Alexandra. "Intensity-modulated radiotherapy for cervical cancer : optimising target volume definition and radiotherapy delivery." Thesis, University of London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.510901.

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9

Bhide, Shreeang Arvind. "Optimization of intensity modulated radiotherapy in head and neck cancer." Thesis, Institute of Cancer Research (University Of London), 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511161.

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10

Lei, Mary Wei-Ching. "Image guided intensity modulated radiotherapy in head and neck cancer." Thesis, University of Surrey, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600034.

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Image Guided Intensity Modulated Radiotherapy (IG-IMRT) incorporates novel imaging strategies into IMRT planning and delivery. FDG-PET/CT imaging may be used to identify potentially radioresistant tumour cell populations in head and neck cancer (HNC). Dose-painting with IMRT is a novel technique which provides an opportunity to widen the therapeutic window by dose escalation to radioresistant subvolumes. The purpose of this thesis was to evaluate the feasibility of th is technique, to provide methodology for identification of the FDG-avid region and to inform on a reasonable dose level to use

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11

Wu, Wing-cheung Vincent, and 胡永祥. "Inverse planning in three-dimensional conformal and intensity modulated radiotherapy." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31246163.

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12

Curtin-Savard, Arthur. "Delivery and verification of intensity-modulated x-ray beams in radiotherapy." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0023/NQ50138.pdf.

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13

Sivabalasingham, S. "Biological and clinical evaluation of intensity modulated radiotherapy for brain tumours." Thesis, University College London (University of London), 2016. http://discovery.ucl.ac.uk/1474887/.

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Intensity modulated radiotherapy has gained attention in recent years as a high precision radiation technique, allowing tumour dose escalation and reductions in high dose to adjacent normal organs. IMRT optimises the therapeutic ratio even further than conventional conformal radiation techniques, providing effective dose for tumour control, whilst minimising side effects. Despite these potential benefits, there is concern regarding long term effects from the associated low dose bath, exposing more normal tissue to lower radiation dose as compared to more conventional radiation techniques. Howe

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14

Urbano, Maria Teresa Guerrero. "Evaluation of intensity modulated radiotherapy in head and neck and pelvic malignancies." Thesis, Institute of Cancer Research (University Of London), 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.510356.

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15

Ho, Kean Fatt. "Optimising dose escalated intensity modulated radiotherapy (IMRT) in head and neck cancer." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508596.

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16

Cowley, Ian Richard. "New approaches to improving the accuracy and outcome of intensity modulated radiotherapy." Thesis, Open University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429545.

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Severaa aspects of the IMRT treatment chain are evaluated with a view to improving the accuracy with which the treatment can be delivered and also the radiobiological outcome for the patient. A safe, non-invasive way of evaluating patient repositioning for multi-fraction treatments is developed and presented, with results highlighting the head-and-neck immobilisation system that provides the best results at Addenbrooke's radiotherapy centre. Previously published dose evaluation metrics sre studied in depth, identifying ways in which they differ. A new method of calculating the popular Gamma in

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17

Hector, Charlotte Lianne. "The impact of patient movement on the delivery of intensity-modulated radiotherapy." Thesis, Institute of Cancer Research (University Of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268887.

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18

Coolens, Catherine. "A study of the complexity necessary for delivery of intensity-modulated radiotherapy." Thesis, Institute of Cancer Research (University Of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413746.

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19

Jena, Rajesh. "Optimisation of radiotherapy for patients with high-grade glioma using diffusion tensor imaging and intensity modulated radiotherapy." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614124.

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20

Tangboonduangjit, Puangpen. "Intensity-modulated radiation therapy dose maps the matchline effect /." Access electronically, 2006. http://www.library.uow.edu.au/adt-NWU/public/adt-NWU20060724.095712/index.html.

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21

Chi, Alexander, Nam Nguyen, William Tse, Gill Sobremonte, Patrick Concannon, and Angela Zhu. "Intensity modulated radiotherapy for sinonasal malignancies with a focus on optic pathway preservation." BioMed Central, 2013. http://hdl.handle.net/10150/610183.

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PURPOSE:To assess if intensity-modulated radiotherapy (IMRT) can possibly lead to improved local control and lower incidence of vision impairment/blindness in comparison to non-IMRT techniques when treating sinonasal malignancies<br>what is the most optimal dose constraints for the optic pathway<br>and the impact of different IMRT strategies on optic pathway sparing in this setting.METHODS AND MATERIALS:A literature search in the PubMed databases was conducted in July, 2012.RESULTS:Clinical studies on IMRT and 2D/3D (2 dimensional/3 dimensional) RT for sinonasal malignancies suggest improved l

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22

Mu, Xiangkui. "Clinical application of intensity and energy modulated radiotherapy with photon and electron beams." Doctoral thesis, Umeå : Strålningsvetenskaper, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-443.

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23

Webster, Gareth John. "Intensity-Modulated Radiotherapy for the Head and Neck : Improvements in Planning and Delivery." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509060.

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24

Nguyen, Nam, Siyoung Jang, Jacqueline Vock, et al. "Feasibility of intensity-modulated and image-guided radiotherapy for locally advanced esophageal cancer." BioMed Central, 2014. http://hdl.handle.net/10150/610350.

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BACKGROUND:In this study the feasibility of intensity-modulated radiotherapy (IMRT) and tomotherapy-based image-guided radiotherapy (IGRT) for locally advanced esophageal cancer was assessed.METHODS:A retrospective study of ten patients with locally advanced esophageal cancer who underwent concurrent chemotherapy with IMRT (1) and IGRT (9) was conducted. The gross tumor volume was treated to a median dose of 70Gy (62.4-75Gy).RESULTS:At a median follow-up of 14months (1-39 months), three patients developed local failures, six patients developed distant metastases, and complications occurred in

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25

Hussien, Mohammad. "Evaluation of detector array technology for the verification of advanced intensity-modulated radiotherapy." Thesis, University of Surrey, 2015. http://epubs.surrey.ac.uk/808445/.

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Purpose: Quality assurance (QA) for intensity modulated radiotherapy (IMRT) has evolved substantially. In recent years, various ionization chamber or diode detector arrays have become commercially available, allowing pre-treatment absolute dose verification with near real-time results. This has led to a wide uptake of this technology to replace point dose and film dosimetry and to facilitate QA streamlining. However, arrays are limited by their spatial resolution giving rise to concerns about their response to clinically relevant deviations. The common factor in all commercial array systems is

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26

Meyer, Jurgen. "Accommodating practical constraints for intensity-modulated radiation therapy by means of compensators." Thesis, Coventry University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369972.

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27

suh, yelin. "DEVELOPMENT AND INVESTIGATION OF INTENSITY-MODULATED RADIATION THERAPY TREATMENT PLANNING FOR FOUR-DIMENSIONAL ANATOMY." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1827.

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Lung cancer is the leading cause of cancer-related deaths worldwide. Radiotherapy is one of the main treatment modalities of lung cancer. However, the achievable accuracy of radiotherapy treatment is limited for lung-based tumors due to respiratory motion. Four-dimensional radiotherapy explicitly accounts for anatomic motion by characterizing the motion, creating a treatment plan that accounts for this motion, and delivering this plan to the moving anatomy. This thesis focuses on the current problems and solutions throughout the course of four-dimensional radiotherapy. For characterization of

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28

Hack, Joshua. "Development and implementation of quality-assurance standards for external beam intensity modulated radiation therapy." Toledo, Ohio : University of Toledo, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=mco1265034762.

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29

Olofsson, Lennart. "Energy and intensity modulated radiation therapy with electrons." Doctoral thesis, Umeå : Department of Radiation Sciences, Radiation Physics, Umeå University, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-491.

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30

Wake, Giulia M. G. H. "Exact minimisation of treatment time for the delivery of intensity modulated radiation therapy." University of Western Australia. School of Mathematics and Statistics, 2009. http://theses.library.uwa.edu.au/adt-WU2009.0195.

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This thesis investigates the exact minimisation of treatment delivery time for Intensity Modulated Radiation Therapy (IMRT) for the treatment of cancer using Multileaf Collimators (MLC). Although patients are required to remain stationary during the delivery of IMRT, inevitably some patient movement will occur, particularly if treatment times are longer than necessary. Therefore minimising the treatment delivery time of IMRT may result in less patient movement, less inaccuracy in the dosage received and a potentially improved outcome for the patient. When IMRT is delivered using multileaf coll

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31

Naik, Mehul S. "Dose calculation of megavoltage IMRT using convolution kernels extracted from GafChromic EBT film-measured pencil beam profiles : a dissertation /." San Antonio : UTHSC, 2006. http://proquest.umi.com/pqdweb?did=1251893631&sid=1&Fmt=2&clientId=70986&RQT=309&VName=PQD.

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32

Pow, Ho-nang Edmond. "Oral health and quality of life after intensity-modulated head and neck radiotherapy for nasopharyngeal carcinoma /." View the Table of Contents & Abstract, 2006. http://sunzi.lib.hku.hk/hkuto/record/B36749333.

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33

Pow, Ho-nang Edmond, and 鮑浩能. "Oral health and quality of life after intensity-modulated head and neck radiotherapy for nasopharyngeal carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B4501565X.

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34

Sakanaka, Katsuyuki. "Dosimetric advantage of intensity-modulated radiotherapy for whole ventricles in the treatment of localized intracranial germinoma." Kyoto University, 2012. http://hdl.handle.net/2433/157445.

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35

Andræ, Nils. "Commissioning and validation of small subfields in Step-and-shoot IMRT." Thesis, Stockholm University, Medical Radiation Physics (together with KI), 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8316.

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<p>One of the most used irradiation techniques in modern radiation therapy is step-and-shoot IMRT. The accuracy of this technique when delivering complex dose distributions strongly depends on the size of the subfields. The aims of this study is to determine the minimum size of subfields that can be used efficiently in Step-and-Shoot IMRT, to investigate the validation process for beam delivery and treatment planning dose calculations, and to find recommendations for practical clinical implementations.</p><p>Two different detectors, a CC04 ion chamber and a SFD stereotactic diode, have been us

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36

Ishida, Yuichi. "Intensity-modulated radiotherapy for cervical esophageal squamous cell carcinoma without hypopharyngeal invasion: dose distribution and clinical outcome." Doctoral thesis, Kyoto University, 2020. http://hdl.handle.net/2433/245831.

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京都大学<br>0048<br>新制・課程博士<br>博士(医学)<br>甲第22146号<br>医博第4537号<br>新制||医||1039(附属図書館)<br>京都大学大学院医学研究科医学専攻<br>(主査)教授大森孝一, 教授富樫かおり, 教授武田俊一<br>学位規則第4条第1項該当<br>Doctor of Medical Science<br>Kyoto University<br>DFAM

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37

Champion, Heather. "Beam angle and fluence map optimization for PARETO multi-objective intensity modulated radiation therapy treatment planning." Medical Physics, 2011. http://hdl.handle.net/1993/8910.

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In this work we introduce PARETO, a multiobjective optimization tool that simultaneously optimizes beam angles and fluence patterns in intensity-modulated radiation therapy (IMRT) treatment planning using a powerful genetic algorithm. We also investigate various objective functions and compare several parameterizations for modeling beam fluence in terms of fluence map complexity, solution quality, and run efficiency. We have found that the combination of a conformity-based Planning Target Volume (PTV) objective function and a dose-volume histogram or equivalent uniform dose -based objective

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38

Shin, Naomi. "Modeling secondary cancer risk following paediatric radiotherapy: a comparison of intensity modulated proton therapy and photon therapy." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106431.

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Proton radiotherapy is known to reduce the radiation dose delivered to normal healthy tissue compared to photon techniques. The increase in normal tissue sparing could result in fewer acute and late effects from radiation therapy. In this work proton therapy plans were created for patients previously treated using photon therapy. Intensity modulated proton therapy (IMPT) plans were planned using inverse planning in Varian's Eclipse treatment planning system with a scanning proton beam model to the same relative biological effectiveness (RBE)-weighted prescription dose as the photon plan. Prot

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39

Al-Roumi, Moh'd. "Verification of patient position during intensity modulated radiotherapy by electronic portal imaging devices using Monte Carlo techniques." Thesis, Queensland University of Technology, 2018. https://eprints.qut.edu.au/116175/1/Moh%27d_Al-Roumi_Thesis.pdf.

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This study generated Monte Carlo (MC) Intensity modulated radiotherapy images to be used as reference images (after calibration) in the verification process of patient set-up errors during radiotherapy treatment. A proposed imaging procedure was developed to estimate the set-up errors during treatment. These developments will improve the accuracy of radiotherapy treatment that is a crucial component of many advanced cancer treatments.

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40

Ahmad, Khalil Dalia Abdel-Moaty [Verfasser]. "Accelerated Intensity Modulated Radiotherapy using Simultaneous Integrated Boost (SIB-IMRT) versus Intensity Modulated Hyperfractionated Accelerated Radiotherapy using Sequential Field (HART-SEQ-IMRT) for primary treatment in patients with locally advanced head and neck Squamous Cell Carcinoma / Dalia Abdel-Moaty Ahmad Khalil." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2012. http://d-nb.info/1027275826/34.

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41

Moreno, Miriam Zarza. "Monte Carlo simulations for dosimetric verification in photon and electron beam radiotherapy." Doctoral thesis, Faculdade de Ciências e Tecnologia, 2012. http://hdl.handle.net/10362/7835.

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Dissertação para obtenção do Grau de Doutor em Engenharia Biomédica<br>One of the primary requirements for successful radiotherapy treatments is the accurate calculation of dose distributions in the treatment planning process. Monte Carlo (MC) dose calculation algorithms are currently recognized as the most accurate method to meet this requirement and to increase even further dose accuracy. The improvements in computer processor technology and the development of variance reduction techniques for calculations have led to the recent implementation and use of MC algorithms for radiotherapy tre

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42

Helal, Azza Mahmoud. "The effect of patient anatomy on optimised intensity modulated radiotherapy dose distributions for head and neck and prostate cancer." Thesis, University of Nottingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438639.

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43

Gomarteli, Kaga [Verfasser], and Frederik [Akademischer Betreuer] Wenz. "Second cancer risk after intensity-modulated and conventional radiotherapy in a small animal model / Kaga Gomarteli ; Betreuer: Frederik Wenz." Heidelberg : Universitätsbibliothek Heidelberg, 2021. http://d-nb.info/1227585578/34.

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44

Kawamura, Mitsue. "A scoring system predicting acute radiation dermatitis in patients with head and neck cancer treated with intensity-modulated radiotherapy." Kyoto University, 2019. http://hdl.handle.net/2433/244519.

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45

Chiu, Siu-hau, and 招兆厚. "A search for optimal radiation therapy technique for lung tumours stereotactic body radiation therapy (SBRT) : dosimetric comparison of 3D conformal radiotherapy, static gantry intensity modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) with flattening filter (FF) or flattening filter-free (FFF) beams." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/196549.

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Materials/Methods: Ten patients who underwent thoracic SBRT with primary stage I (T1/2N0) lung cancer or oligometastatic lung lesion, with PTV diameter ≤ 5cm were selected and were immobilized with Easyfoam or Vac-Lock. Planned/treated with inspiratory breath-hold (25 seconds, 70 to 80% of vital capacity) assisted with Active Breathing Control (ABC). Four treatment plans: non-coplanar 3DCRT, coplanar static gantry IMRT, coplanar VMAT (FF) and VMAT (FFF) were generated. Field arrangements, either static fields or partial arcs (duration=20 sec) were used to avoid direct beam entry to contralat

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46

Javedan, Khosrow. "Investigation of Buildup Dose for Therapeutic Intensity Modulated Photon Beams in Radiation Therapy." Scholar Commons, 2010. http://scholarcommons.usf.edu/etd/3449.

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Buildup dose of Mega Voltage (MV) photon beams can be a limiting factor in intensitymodulated radiation therapy (IMRT) treatments. Excessive doses can cause patient discomfort and treatment interruptions, while underdosing may lead to local failure. Many factors which contribute to buildup dose, including the photon beam energy spectrum, scattered or contaminant radiation and their angular distribution, are not modeled well in commercial treatment planning systems. The accurate Monte Carlo method was employed in the studies to estimate the doses. Buildup dose of 6MV photon beams was investigat

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47

Nutting, Christopher. "Can intensity-modulated radiotherapy (IMRT) be used to reduce toxicity and improve tumour control in patients with head and neck cancer?" Thesis, City University London, 2012. http://openaccess.city.ac.uk/1128/.

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Radiotherapy is commonly used in the treatment of head and neck cancer. For early stage tumours, conventional radiotherapy techniques have a high cure rate and low levels of long-term complications. Patients with more advanced cancers have much lower cure rates and high levels of treatment-related complications. Intensity modulated radiotherapy (IMRT) is a new form of focussed radiation therapy. It has been used to reduce the radiation dose to normal tissue structures and increase the dose delivered to tumour bearing tissues. This potentially allows reduced side effects and increased tumour co

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48

Inokuchi, Haruo. "Clinical effect of multileaf collimator width on the incidence of late rectal bleeding after high-dose intensity-modulated radiotherapy for localized prostate carcinoma." Kyoto University, 2016. http://hdl.handle.net/2433/215942.

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49

Johansson, Jonas. "Comparative Treatment Planning in Radiotherapy and Clinical Impact of Proton Relative Biological Effectiveness." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6593.

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50

McKenna, Frederick W. "Studies of cell survival curve fitting, effective doses for radiobiological evaluation in SBRT treatment techniques and the dependence of optical density growth in Gafchromic EBT film used in IMRT." Oklahoma City : [s.n.], 2009.

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