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Journal articles on the topic 'Interaction formulation'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Rashid, Md Abdur, Amged Awad Elgied, Yahya Alhamhoom, et al. "Excipient Interactions in Glucagon Dry Powder Inhaler Formulation for Pulmonary Delivery." Pharmaceutics 11, no. 5 (2019): 207. http://dx.doi.org/10.3390/pharmaceutics11050207.

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Purpose: This study describes the development and characterization of glucagon dry powder inhaler (DPI) formulation for pulmonary delivery. Lactose monohydrate, as a carrier, and L-leucine and magnesium stearate (MgSt) were used as dispersibility enhancers for this formulation. Methods: Using Fourier-transform infrared (FTIR) spectroscopy, Differential Scanning Calorimetry (DSC), and Raman confocal microscopy, the interactions between glucagon and all excipients were characterized. The fine particle fractions (FPFs) of glucagon in different formulations were determined by a twin stage impinger

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Hernawan, Hernawan, Septi Nurhayati, Khoirun Nisa, A. W. Indrianingsih, Cici Darsih, and Muhammad Kismurtono. "FORMULATION AND IN VITRO STUDY OF PROPRANOLOL HYDROCHLORIDE CONTROLLED RELEASE FROM CARBOXYMETHYL CHITOSAN-BASED MATRIX TABLETS." Indonesian Journal of Chemistry 13, no. 3 (2013): 242–47. http://dx.doi.org/10.22146/ijc.21283.

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Formulation and in vitro study of propranolol hydrochloride controlled release from carboxymethyl chitosan-based matrix tablets have been conducted. Formulations with various concentrations of carboxymethyl chitosan 2% (F1), 4% (F2), 6% (F3) were done by wet granulation method. Compatibility test was conducted by XRD and FTIR spectroscopy to determine interaction between propranolol hydrochloride and polymer excipients. Dissolution profiles was obtained through in vitro tests release using simulated gastric fluid (without enzymes, pH 1.2) for the first 2 h and followed by simulated intestinal

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Vaishnavi, B. Pawar*1 Swapnil P. Pimpale1 Kavita B. Vikhe2. "Formulation and Evaluation of Meloxicam Ointment: A Comprehensive Study on Physicochemical Properties, Pre-formulation Studies, and In Silico Molecular Docking Analysis." International Journal in Pharmaceutical Sciences 2, no. 4 (2024): 1128–38. https://doi.org/10.5281/zenodo.11079688.

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Meloxicam, a nonsteroidal anti-inflammatory drug (NSAID), holds promise for topical application due to its potent anti-inflammatory and analgesic properties. This study aimed to investigate the feasibility of formulating a Meloxicam ointment through a combined approach of molecular docking, formulation, and in vitro evaluation. Initially, molecular docking studies were conducted to assess the interaction of Meloxicam with key skin receptors implicated in inflammation, guiding the selection of excipients for optimal drug delivery. Subsequently, Meloxicam ointment formulations were prepared usin

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Johannesma, P. I. M., and H. F. P. van den Boogaard. "Stochastic formulation of neural interaction." Acta Applicandae Mathematica 4, no. 2-3 (1985): 201–24. http://dx.doi.org/10.1007/bf00052461.

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Thamanna, P., and Prasanth M. L. Lal. "Comparative review on polyherbal and monoherbal cosmetic formulations." i-manager's Journal on Chemical Sciences 3, no. 1 (2023): 32. http://dx.doi.org/10.26634/jchem.3.1.19379.

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This comparative review explores the characteristics and benefits of polyherbal and monoherbal cosmetic formulations. Formulations containing two or more herbs are called polyherbal formulations. Drug formulation in Ayurveda is based on the use of a single drug or more than one drug. A monoherbal formulation contains only one herb. The problem of polyherbal formulation occurs due to sources and manufacturing processes, patients, drug-herb interaction, toxicity, and improper manufacturing. Polyherbal formulations mean the use of more than one herb in a therapeutic preparation. In Ayurveda, mult

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Peschka, Dirk, Andrea Zafferi, Luca Heltai, and Marita Thomas. "Variational Approach to Fluid-Structure Interaction via GENERIC." Journal of Non-Equilibrium Thermodynamics 47, no. 2 (2022): 217–26. http://dx.doi.org/10.1515/jnet-2021-0081.

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Abstract We present a framework to systematically derive variational formulations for fluid-structure interaction problems based on thermodynamical driving functionals and geometric structures in different coordinate systems by suitable transformations within this formulation. Our approach provides a promising basis to construct structure-preserving discretization strategies.

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P, Mech, Lakhawat SS, Sharma G, and Kotecha M. "Evaluation of Anxiolytic effect of Polyherbal Formulation on Social Interaction, Light and Dark and Elevated Plus Maze in Wistar albino Rat Models." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 04 (2024): 1148–61. https://doi.org/10.25258/ijddt.14.4.32.

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Background and Objective: Anxiety is a widespread mental illness that impacts millions of individuals globally. The investigation of safe and effective treatments for anxiety disorders is vital due to their substantial impact on world health. There is hope for the creation of new anxiolytic treatments through the use of traditional medicinal plants. The objective of this study was to assess the anxiolytic properties of a polyherbal formulation made up of nine medicinal plants that have been shown to have potential uses in the treatment of anxiety disorders. Methods: Wistar albino rats were giv

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Simonen, Mika. "Formulation in clinical interviews." Communication and Medicine 9, no. 2 (2013): 133–43. http://dx.doi.org/10.1558/cam.v9i2.133.

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Formulation, according to Garfinkel and Sacks (1986 [1969]), refers to speakers’ ways of talking about the current interaction. This article explores how formulations are used in clinical assessment interviews as a way of providing evidence of the respondent’s capacities that are currently assessed. The videotaped data are drawn from the clinical interviews of unemployed adults and older persons. The data are analyzed using conversation analysis (CA). The article shows how formulation is achieved through vocalized and/or embodied actions (e.g. nodding, index finger pointing), in conjunction wi

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Demattè, R., L. Michael, and N. Nikiforakis. "Reacting condensed phase explosives in direct contact." Journal of Applied Physics 131, no. 9 (2022): 095901. http://dx.doi.org/10.1063/5.0075851.

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In this article, we present a new formulation and an associated algorithm for the simultaneous numerical simulation of multiple condensed phase explosives in direct contact with each other, which may also be confined by (or interacting with one or more) compliant inert materials. Examples include composite rate-stick (i.e., involving two explosives in contact) problems, interaction of shock waves with chemically active particles in condensed-phase explosives, and devices such as detonators and boosters. There are several formulations that address the compliant or structural response of confine

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Khan, Rahman Ullah, Shefaat Ullah Shah, Sheikh Abdur Rashid, et al. "Lornoxicam-Loaded Chitosan-Decorated Nanoemulsion: Preparation and In Vitro Evaluation for Enhanced Transdermal Delivery." Polymers 14, no. 9 (2022): 1922. http://dx.doi.org/10.3390/polym14091922.

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Nanoemulsions are promising drug delivery systems for the administration of poorly soluble drugs like lornoxicam (LRX) by oral or parenteral routes. Such formulations work perfectly for transdermal delivery of lornoxicam-type drugs. It has also been established that formulating such a delivery system is highly dependent on the presence, type, and concentration of excipients taking part in the formulation. The inherent characteristics of nanoemulsion (NE), i.e., smaller globule size and excipient nature, facilitate the drug’s passage through skin. The current study was aimed at the development

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Rahim, N. F. A., N. Muhammad, N. Abdullah, B. A. Talip, and K. H. Poh. "The interaction effect and optimal formulation of selected polyherbal extracts towards antioxidant activity." Food Research 4, no. 6 (2020): 2042–48. http://dx.doi.org/10.26656/fr.2017.4(6).281.

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Past study showed that lemongrass (Cymbopogon citratus), curry leaves (Murrya koenigii), turmeric (Curcuma longa) and ginger (Zingiber officinale) contain phytochemicals associated with antioxidant properties. However, all the herbs are tested individually and rarely mix together. This study was conducted to examine the antioxidant properties and interaction effect when combined. The plants studied were decocted with distilled water. Eighteen formulations of aqueous extracts were established using simplex lattice mixture design that was generated by Design Expert software. The antioxidant prop

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Lennox, Tammy, and Angela kennedy. "Using Structured Compassion Focused Formulations Towards Change in Couples and Organisations." OBM Integrative and Complementary Medicine 08, no. 03 (2023): 1–25. http://dx.doi.org/10.21926/obm.icm.2303030.

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The current article describes the application of the Compassion Focussed (CF) formulation to the interaction between individuals and their social context. The standard CF formulation [1] would see the person’s fears as inadvertently reinforced by their attempts to cope with the underlying issue. However, sometimes such attempts to cope can also reinforce the fears of another person or party. Interpersonal CF formulations could provide a compassionate, non-blaming way of enlightening people in their interactions to remove blame and focus intervention plans on what is helpful for each party, in

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Ashok, Kumar Sharma, Pushpendra Singh Naruka Dr., Shankar Soni Mr., Mohit Khandelwal Mr., Shaneza Aman Ms., and Sharma Mukesh. "DEVELOPMENT AND EVALUATION HYDROGEL OF KETOCONAZOLE." International Journal of Current Pharmaceutical Review and Research 11, no. 3 (2019): 01–11. https://doi.org/10.5281/zenodo.12672946.

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The main aim of this study was to develop a topical drug delivery (Hydrogel) ofKetoconazole to reduce the dose of the active drug, to improve patient compliance, to avoidthe side effects and increase local onset absorption and action. Ketoconazole interfarewith 14-α sterol demethylase, a cytochrome P-450 enzyme essential for conversion oflanosterol to ergosterol. These turn in inhibition in synthesis of ergosterol and also enhancecellular permeability of fungus due to reduced amounts of ergosterol present in the fungal cellmembrane. Methods: Topical Hydrogel formulations development of K

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Shiva Kumar, Y., M. Rasagna, and T. Mangilal. "Preparation and Evaluation of Tapentadol Hydrochloride Solid Lipid Nanoparticles." Journal of Drug Delivery and Therapeutics 9, no. 4-A (2019): 618–24. http://dx.doi.org/10.22270/jddt.v9i4-a.3513.

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Tapentadol Hydrochloride is a centrally acting opioid analgesic used for the treatment of musculoskeletal pain. The aim of the present study is to release the drug at a controlled rate by formulating solid lipid nanoparticles using Hot Homogenization method. In the present study SLN’s are prepared by using Glycerol Monostearate and Stearic acid as lipids and Poloxamer-188 as stabilizer in different ratios in order to get the optimized formulation. The solid lipids and drug were evaluated for drug interactions by using FTIR, DSC, and surface morphology by SEM in order to select the effective fo

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15

Abiona, Olaitan, David Wyatt, Jasdip Koner, and Afzal Mohammed. "The Optimisation of Carrier Selection in Dry Powder Inhaler Formulation and the Role of Surface Energetics." Biomedicines 10, no. 11 (2022): 2707. http://dx.doi.org/10.3390/biomedicines10112707.

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This review examines the effects of particle properties on drug–carrier interactions in the preparation of a dry powder inhaler (DPI) formulation, including appropriate mixing technology. The interactive effects of carrier properties on DPI formulation performance make it difficult to establish a direct cause-and-effect relationship between any one carrier property and its effect on the performance of a DPI formulation. Alpha lactose monohydrate remains the most widely used carrier for DPI formulations. The physicochemical properties of α-lactose monohydrate particles, such as particle size, s

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Baraldi, Claudio. "Using formulations to manage conflicts in classroom interactions." Language and Dialogue 9, no. 2 (2019): 193–216. http://dx.doi.org/10.1075/ld.00038.bar.

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Abstract In classroom interactions, facilitation of children’s autonomous choice of acting (agency) may produce conflicts among children. While facilitation does not have the function of managing these conflicts, it shares some types of action with conflict mediation, one of which is formulation. Formulation elaborates the gist of previous utterances and enhances interlocutors’ actions. This paper provides a qualitative analysis of nine transcribed sequences of interaction, included into five different programs of facilitation. The analysis shows that formulations fulfil two different function

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17

Dong, Zhifei, and James T. Kirby. "THEORETICAL AND NUMERICAL STUDY OF WAVE-CURRENT INTERACTION IN STRONGLY-SHEARED FLOWS." Coastal Engineering Proceedings 1, no. 33 (2012): 2. http://dx.doi.org/10.9753/icce.v33.waves.2.

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The application of wave-current interaction theory in ocean circulation models has been extensively developed over the past decade, with formulations extended to three dimensions and based either on radiation stress formulations or on the Craik-Leibovich formulation. However, few of these studies consider the interaction of waves with relatively strongly sheared current, in which current shear can affect linear wave dynamics at leading order. The problem arises from the study of the evolution of highly concentrated sediment plumes developing at the mouth of small mountainous rivers. Although t

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18

P. Jyothishna and A. Madhusudhan Reddy. "Formulation And In Vitro Evaluation Of Dalfampridine Sustained Release Tablets By Using Various Polymers." International Journal of Allied Medical Sciences and Clinical Research 12, no. 4 (2024): 562–73. https://doi.org/10.61096/ijamscr.v12.iss4.2024.562-573.

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In present investigation the sustained release tablets of Dalfampridine was formulated to study effect various natural polymers of Tragacanth, Acacia gum and Xanthan gum. The model is based on a novel dosage form designed to deliver a drug into the gastrointestinal tract in a controlled manner. Matrix tablets were prepared by direct compression method. As a pre-requisite and part of pre-formulation studies, drug along with selected excipients and as optimized formulation was subjected to FT-IR studies. It was found that no interaction among excipients occurred, as no extra peaks obtained. Tabl

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Rashid, Md Abdur, Saiqa Muneer, Tony Wang, et al. "Puerarin dry powder inhaler formulations for pulmonary delivery: Development and characterization." PLOS ONE 16, no. 4 (2021): e0249683. http://dx.doi.org/10.1371/journal.pone.0249683.

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This study aims at developing and characterizing the puerarin dry powder inhaler (DPI) formulations for pulmonary delivery. The inhalable particles size (<2 μm) was accomplished by micronization and its morphology was examined by scanning electron microscopy (SEM). The puerarin-excipient interaction in powder mixtures was analyzed by using Fourier transform infrared spectroscopy (FTIR), Raman confocal microscopy, X-Ray powder Diffraction (XRD), and differential scanning calorimetry (DSC) methods. Using a Twin stage impinger (TSI), the in-vitro aerosolization of the powder formulations was c

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Naga Durga, D. Hema, T. Lakshmi Sowjanya, T. Pavani, and Lohithasu Duppala. "Formulation development and in-vitro evaluation of Molsidomine matrix tablets for colon specific release." Journal of Drug Delivery and Therapeutics 10, no. 2 (2020): 59–68. http://dx.doi.org/10.22270/jddt.v10i2.3900.

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Colon targeted tablets were prepared in two steps. Initially core tablets were prepared and then the tablets were coated by using different pH dependent polymers. Ethyl cellulose, Eudragit L100 and S100 were used as coating polymers. FT-IR studies were carried out to find out the possible interaction between the selected drugs and polymer. FT-IR studies revealed that there was no interaction between the selected drug and excipients. The pre-compression blend of all formulations was subjected to various flow property tests and all the formulations passed the tests. The tablets were coated by us

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A, VASANTHAN, SENTHILKUMAR KL, GOKULAN PD, et al. "FORMULATION AND EVALUATION OF EFAVIRENZ TABLET USING MORINGA OLEIFERA AS A NATURAL POLYMER." Current Research in Pharmaceutical Sciences 12, no. 1 (2022): 51–58. http://dx.doi.org/10.24092/crps.2022.120108.

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This study describes a systemic approach for the formulation and evaluation of Efavirenz tablets and has been done in this work using Moringa Oleifera as a natural polymer at different concentrations. In order to identify the medication, melting point, solubility, and FTIR analysis were used. DSC was used for investigating the drug polymer interactions. Consequently, no interaction between the medicine and polymer used in the formulation was detected. The formulations were created by blending medication and excipients, then analysing them for Angle of repose, Bulk density, Tapered bulk density

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PADMA PRIYA, S., AN Rajalakshmi, and P. Ilaveni. "FORMULATION AND EVALUATION OF MUCOADHESIVE MICROSPHERES OF AN ANTI-MIGRAINE DRUG." Journal of Drug Delivery and Therapeutics 8, no. 5 (2018): 465–74. http://dx.doi.org/10.22270/jddt.v8i5.1943.

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Objective: The objective of this research work is to develop and evaluate mucoadhesive microspheres of an anti-migraine drug for sustained release. Materials and Methods: Mucoadhesive microspheres were prepared by emulsification method using Sodium alginate (SA), polyvinyl pyrrolidone (PVP) and Chitosan in the various drug-polymer ratios of 1:1, 1:2 and 1:3. Nine formulations were formulated and evaluated for possible drug polymer interactions, percentage yield, micromeritic properties, particle size, drug content, drug entrapment efficiency, drug loading, swelling index, In-vitro wash off tes

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Huang, Jiayi, Shiqi Hong, Lucas Yuan Hao Goh та ін. "Investigation on the Combined Effect of Hydroxypropyl Beta-Cyclodextrin (HPβCD) and Polysorbate in Monoclonal Antibody Formulation". Pharmaceuticals 17, № 4 (2024): 528. http://dx.doi.org/10.3390/ph17040528.

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Monoclonal antibodies require careful formulation due to their inherent stability limitations. Polysorbates are commonly used to stabilize mAbs, but they are prone to degradation, which results in unwanted impurities. KLEPTOSE® HPβCD (hydroxypropyl beta-cyclodextrin) has functioned as a stable stabilizer for protein formulations in our previous research. The current study investigates the collaborative impact of combining polysorbates and HPβCD as excipients in protein formulations. The introduction of HPβCD in formulations showed it considerably reduced aggregation in two model proteins, beva

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Westmeyer, Hans. "On the Structure of Case Formulations." European Journal of Psychological Assessment 19, no. 3 (2003): 210–16. http://dx.doi.org/10.1027//1015-5759.19.3.210.

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Summary: A case formulation is the result of a complex process of interaction between assessing and assessed persons. There are many factors that exert their influence on this process and its result, although they are usually not even mentioned in the case formulation. This raises the question “What are the structure and characteristics of an adequate case formulation?”. Two different answers to this question are elaborated, both of which rely on an understanding of case formulations as structured sets of idiographic hypotheses, and are distinguished by different explications of the concept of

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Deepika, K., and S. Chellaram. "Formulation and evaluation of bupropion hydrochloride sustained release tablets using combination of hydrophilic polymers." Pharmaceutical and Chemical Journal 1, no. 3 (2014): 1–8. https://doi.org/10.5281/zenodo.13691518.

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The objective of the present study was to develop the oral sustained release tablets of Bupropion hydrochloride using combination of hydrophilic polymers. Bupropion Hydrochloride is a Anti-Depressant agent used in symptomatic treatment of depression, maniac, and smoking withdrawal conditions. FT-IR studies were carried to know the interaction, showed that absence of any interactions between the drug and polymers. Optimization of the formulation was done by studying effect of drug to polymer ratio on drug release. The physicochemical properties of tablets were found within the limits. The drug

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de Castro, Victor Velho, Cristiano Ev, Leandro Câmara Noronha, et al. "Next-Generation Lubricity in Deep Drawing: The Synergistic Benefits of PIL and Talc on Water-Based Lubricants." Metals 14, no. 6 (2024): 705. http://dx.doi.org/10.3390/met14060705.

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This study aims to assess the effectiveness of water-based formulations featuring m-2HEAOL and talc particles in deep drawing applications. The coefficient of friction (COF) was measured through bending under tension (BUT) tests, while the interaction mechanism between protic ionic liquid (PIL) and talc particles was analysed using FTIR, XPS, and TGA analyses. The results indicate that the formulation containing 8 wt% PIL and 0.5 wt% talc exhibited the best lubricating performance. This was due to the interaction of the PIL oleate molecules with the Mg found in the talc basal layer, which enha

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Koh, B. H., Z. Li, P. Dharap, S. Nagarajaiah, and M. Q. Phan. "Actuator Failure Detection Through Interaction Matrix Formulation." Journal of Guidance, Control, and Dynamics 28, no. 5 (2005): 895–901. http://dx.doi.org/10.2514/1.11932.

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&NA;. "Saquinavir soft gelatin formulation: interaction with ritonavir." Inpharma Weekly &NA;, no. 1309 (2001): 19. http://dx.doi.org/10.2165/00128413-200113090-00046.

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Boujot, Jacqueline. "Mathematical formulation of fluid-structure interaction problems." ESAIM: Mathematical Modelling and Numerical Analysis 21, no. 2 (1987): 239–60. http://dx.doi.org/10.1051/m2an/1987210202391.

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Souli, M., A. Ouahsine, and L. Lewin. "ALE formulation for fluid–structure interaction problems." Computer Methods in Applied Mechanics and Engineering 190, no. 5-7 (2000): 659–75. http://dx.doi.org/10.1016/s0045-7825(99)00432-6.

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Tarantelli, A., and L. S. Cederbaum. "Configuration-interaction formulation of the Dyson equation." Physical Review A 45, no. 5 (1992): 2790–806. http://dx.doi.org/10.1103/physreva.45.2790.

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Schwarz, Julia C., Victoria Klang, Magdalena Hoppel, Denise Mahrhauser, and Claudia Valenta. "Natural microemulsions: Formulation design and skin interaction." European Journal of Pharmaceutics and Biopharmaceutics 81, no. 3 (2012): 557–62. http://dx.doi.org/10.1016/j.ejpb.2012.04.003.

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Gerber, Martin, and Marek Nowakowski. "Lagrangian formulation of CP-exotic mesons interaction." Nuclear Physics A 548, no. 4 (1992): 681–700. http://dx.doi.org/10.1016/0375-9474(92)90649-5.

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Hebbar, K. P., R. D. Lumsden, J. A. Lewis, S. M. Poch, and B. A. Bailey. "Formulation of mycoherbicidal strains ofFusarium oxysporum." Weed Science 46, no. 4 (1998): 501–7. http://dx.doi.org/10.1017/s0043174500090962.

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Biomass abundant in chlamydospores obtained by liquid fermentation of mycoherbicidal strains ofFusarium oxysporumwas incorporated into alginate prills with various food substrates and granular formulations such as corn flour : starch, wheat flour : kaolin, rice : wheat flour, and rice : wheat gluten formulations. These fungal strains cause vascular wilts in coca (Erythroxylum cocavar.coca) and in poppy (Papavar somniferum). Fungal strain, formulation method, and interaction of these two parameters significantly affected the shelf life of the formulations at room temperature as well as the abil

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Deepika, V., and S. Srinu Naik. "Tofacitinib Citrate-Loaded Topical Gel for the Treatment of Rheumatoid Arthritis: Formulation and In-vitro-In-vivo Characterization." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 03 (2024): 1366–71. http://dx.doi.org/10.25258/ijpqa.15.3.43.

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This study aims to create and assess the anti-arthritic activity of tofacitinib citrate (TC) as a topical gel formulation. Using the gelling agent Carbopol 980 P, seven gel formulations were formed. The gel formulations were assessed for pH, drug content, spreadability, homogeneity, and in-vitro diffusion profile. Out of all the formulations, G7 exhibited superior release characteristics (99.1%) in comparison to the other formulations. The DSC research revealed a strong endothermal peak at 214.17°C and demonstrated an interaction with the excipients taken into consideration in this investigati

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Pachos, J., and E. Solano. "Generation and degree of entanglement in a relativistic formulation." Quantum Information and Computation 3, no. 2 (2003): 115–20. http://dx.doi.org/10.26421/qic3.2-3.

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The generation of entangled states and their degree of entanglement are studied in a relativistic formulation for the case of two interacting spin-1/2 charged particles. In the realm of quantum electrodynamics, we revisit the interaction that produces entanglement between the spin components of covariant Dirac spinors describing the two particles. In this way, we derive the relativistic version of the spin-spin interaction, widely used in the nonrelativistic regime. Following this consistent approach, the relativistic invariance of the generated entanglement is discussed.

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Kumari, Sapna, Anju Goyal, Madhukar Garg, Angela Antonescu, and Rakesh K. Sindhu. "Lyotropic Liquid Crystal System for Drug Delivery of Astaxanthin: Physical Characterization and Enhanced Antioxidant Potential." Crystals 13, no. 1 (2023): 142. http://dx.doi.org/10.3390/cryst13010142.

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Astaxanthin is a xanthophyll carotenoid, well known for its potent anti-inflammatory and antioxidant properties, owing to its unsaturated molecular structure. Aquatic plants and animals contain the hydrophobic carotenoid astaxanthin, which is thought to possess a number of advantageous biological traits. However, due to its weak bioavailability and low water solubility, its use as a nutraceutical in food is currently restricted. Cubosomal encapsulation has been considered an effective alternative for improving the bioavailability and solubility of hydrophobic bioactives. The current paper aime

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Lou, P., G.-L. Dai, and Q.-Y. Zeng. "Modal Coordinate Formulation for a Simply Supported Bridge Subjected to a Moving Train Modelled as Two-Stage Suspension Vehicles." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 219, no. 10 (2005): 1027–40. http://dx.doi.org/10.1243/095440605x31940.

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Modal coordinate formulation for analysing the dynamic interaction between a moving train and a simply supported bridge is presented in this article. The train is composed of a series of identical vehicles, and each vehicle is modelled as a four-wheelset mass-spring-damper multi-rigid body system with two-stage suspension having ten degrees of freedom (DOFs). A simply supported bridge, together with the track, is modelled as a Bernoulli-Euler beam. The deflection of the beam is described by superimposing modes. The train and the beam are regarded as an entire dynamic system, and then the modal

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Priya, B. Panchal G. N. Dhembre* U. T. Jadhao S. T. Thoke D. A. Rathod S. A. Wathore V. R. Kauthekar. "Development And Evaluation Of Orodispersible Film Of Telmisartan." International Journal in Pharmaceutical Sciences 2, no. 10 (2024): 1652–61. https://doi.org/10.5281/zenodo.14000663.

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The objective of this research work was the Development and evaluation of Orodispersible film of Telmisartan as model drug. This formulation was aimed to deliver the quick onset of action of drug Telmisartan in the management of hypertension, so as to enhance patient’s compliance. The orodispersible film of Telmisartan was prepared by solvent casting method. Orodispersible film of Telmisartan was formulated using two different film forming agent HPMC E5 and Pullulan along with crosspovidone as a superdisintegrant.Total six formulations were developed using varying concentration of film f

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Suliman, Ridhwaan, and Oliver Oxtoby. "A Quadratic Elasticity Formulation for Dynamic Interacting Structures in Flow." MATEC Web of Conferences 347 (2021): 00033. http://dx.doi.org/10.1051/matecconf/202134700033.

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The deformation of slender elastic structures due to the motion of surrounding fluid is a common multiphysics problem encountered in many applications. In this work we detail the development of a numerical model capable of solving such strongly-coupled fluid-structure interaction problems, and analyse the dynamic behaviour of multiple interacting bodies under fluid loading. In most fluid-structure interaction problems the deformation of slender elastic bodies is significant and cannot be described by a purely linear analysis. We present a new formulation to model these larger displacements. By

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Thakral, Seema, Jayesh Sonje, Bhushan Munjal, and Raj Suryanarayanan. "Stabilizers and their interaction with formulation components in frozen and freeze-dried protein formulations." Advanced Drug Delivery Reviews 173 (June 2021): 1–19. http://dx.doi.org/10.1016/j.addr.2021.03.003.

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Ibarra, Manuel, Marta Vázquez, and Pietro Fagiolino. "Sex‐by‐formulation interaction in bioequivalence studies: the importance of formulations and experimental conditions." British Journal of Clinical Pharmacology 85, no. 4 (2019): 669–71. http://dx.doi.org/10.1111/bcp.13829.

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Begum, Mobina, Abdul Rawoof, D. Jasmine, and Sana Fatima. "Formulating and evaluating a gel that contains Eletriptan-loaded transferosomes." Journal of Drug Delivery and Therapeutics 14, no. 2 (2024): 59–65. http://dx.doi.org/10.22270/jddt.v14i2.6409.

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Transdermal-vesicular drug delivery systems offer various advantages over conventional drug delivery systems, such as bypassing first-pass metabolism, site-specific delivery, reduced dosing frequency, and more. The objective of the present research involves the formulation and in-vitro evaluation of Eletriptan transferosomal gel to reduce dosing frequency. Transferosomes act as vehicles for on-site drug delivery, and they are vesicular systems with a flexible membrane. By formulating this type, we can achieve a higher concentration at the site of action, thereby reducing dosing frequency.&#x0D

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Kumar, AK Sathish, N. Audinarayana, GNA Lakshmi, and D. Jothieswari. "Formulation and evaluation of dosulepin HCL mucoadhesive buccal films." International Journal of Research in Pharmaceutical Sciences 16, no. 1 (2025): 91–102. https://doi.org/10.26452/ijrps.v16i1.4742.

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The current study aimed to develop Dosulepin HCl as a buccal bioadhesive film formulation to reduce dosing frequency by providing sustained drug release at therapeutic concentrations. Dosulepin HCl exhibits multiple pharmacological actions, including antihistamine, antiadrenergic, antiserotonergic, anticholinergic, and sodium channel-blocking properties, making it effective for various indications. Although primarily used for conditions like psychogenic facial pain, treatment efficacy with dosulepin often requires prolonged therapy, sometimes up to one year. Among various formulations, formula

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Vázquez Carranza, Ariel. "Remembering and noticing." Spanish in Context 13, no. 2 (2016): 212–36. http://dx.doi.org/10.1075/sic.13.2.03vaz.

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The present investigation uses the methodology of Conversation Analysis to study the particle ah in Mexican Spanish interactions. It looks at ah as a change-of-state token in remembering and noticing sequences. Similar to previous studies (e.g., Edwards and Middleton 1986; Goodwin 1987; and Drew 1989), this investigation aims to show how cognitive processes are socially organised in interaction. Three types of remembering sequences are identified and described: assisted, metacognitive, and spontaneous remembering. It is suggested that in these type of sequences, ah marks the end of the cogniti

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., Manishaanjane, Shikha Agrawal, and Amreen Khan. "FORMULATION AND EVALUATION OF NANOSUSPENSION OF VALSARTAN." International Journal of Current Pharmaceutical Research 10, no. 2 (2018): 68. http://dx.doi.org/10.22159/ijcpr.2018v10i2.25874.

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Objective: The objective of the present research work was to formulate and evaluate Valsartan nanosuspension by nanoprecipitation ultra sonication method using different polymers to enhance solubility and bioavailability of the poorly water-soluble drug.Methods: Formulation of nanosuspension of valsartan by nanoprecipitation technique was used. The nanosuspension formulations were prepared using different polymers such as hydroxyl propyl methyl cellulose E50, polyvinyl pyrollidone k-30, polyethene glycol 6000 and sodium lauryl sulphate was used as the surfactant.Results: The formulation of nan

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CHEN, LUSHENG, and KURT HALLER. "QUARK CONFINEMENT AND COLOR TRANSPARENCY IN A GAUGE-INVARIANT FORMULATION OF QCD." International Journal of Modern Physics A 14, no. 17 (1999): 2745–67. http://dx.doi.org/10.1142/s0217751x99001378.

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We examine a nonlocal interaction that results from expressing the QCD Hamiltonian entirely in terms of gauge-invariant quark and gluon fields. The interaction couples one quark color-charge density to another, much as electric charge densities are coupled to each other by the Coulomb interaction in QED. In QCD, this nonlocal interaction also couples quark color-charge densities to gluonic color. We show how the leading part of the interaction between quark color-charge densities vanishes when the participating quarks are in a color singlet configuration, and that, for singlet configurations,

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Jaya, S., and V. Amala. "FORMULATION AND IN VITRO EVALUATION OF ORAL DISINTEGRATING TABLETS OF AMLODIPINE BESYLATE." International Journal of Applied Pharmaceutics 11, no. 1 (2019): 49. http://dx.doi.org/10.22159/ijap.2019v11i1.28457.

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Objective: The present investigation was undertaken with an objective of formulating oral disintegrating tablets of amlodipine besylate to enhance convenience and compliance of the elderly and pediatric patients for better therapeutic efficacy.Methods: The tablets were prepared by using direct compression method and evaluated for weight variation, hardness, friability, wetting time, disintegration time and in vitro drug release study. Prepared tablets were evaluated for compatibility by Fourier transform infrared spectroscopy.Results: Fourier transform infrared spectroscopy studies revealed th

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Phan, Tin, James J. Elser, and Yang Kuang. "Rich Dynamics of a General Producer–Grazer Interaction Model under Shared Multiple Resource Limitations." Applied Sciences 13, no. 7 (2023): 4150. http://dx.doi.org/10.3390/app13074150.

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Organism growth is often determined by multiple resources interdependently. However, growth models based on the Droop cell quota framework have historically been built using threshold formulations, which means they intrinsically involve single-resource limitations. In addition, it is a daunting task to study the global dynamics of these models mathematically, since they employ minimum functions that are non-smooth (not differentiable). To provide an approach to encompass interactions of multiple resources, we propose a multiple-resource limitation growth function based on the Droop cell quota

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Srikanth Reddy, Poreddy, Penjuri Subhash Chandra Bose, Vuppula Sruthi, and Damineni Saritha. "INVESTIGATION OF KONDAGOGU GUM TO DEVELOP TRANSDERMAL FILM OF REPAGLINIDE." Asian Journal of Pharmaceutical and Clinical Research 11, no. 4 (2018): 440. http://dx.doi.org/10.22159/ajpcr.2018.v11i4.24873.

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Objective: In the present study, an attempt was made to develop polymeric blend transdermal patch of repaglinide using hydroxypropyl methyl cellulose (HPMC) K4M and kondagogu gum.Methods: A series of repaglinide drug-incorporated HPMC K4M-kondagogu gum matrix films were prepared by solvent casting method. The prepared transdermal films were evaluated for various parameters such as thickness, tensile strength, folding endurance, % elongation, % moisture content, % moisture uptake, % drug content, in vitro drug release, and drug excipient compatibility.Results: The Fourier-transform infrared spe

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