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1

Wood, Jonathan, Dennis Palms, Quan Trong Luu, Krasimir Vasilev, and Richard Bright. "Investigating Simulated Cellular Interactions on Nanostructured Surfaces with Antibacterial Properties: Insights from Force Curve Simulations." Nanomaterials 15, no. 6 (2025): 462. https://doi.org/10.3390/nano15060462.

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This study investigates the simulation of interactions between cells and antibacterial nanostructured surfaces. Understanding the physical interaction forces between cells and nanostructured surfaces is crucial for developing antibacterial materials, yet existing physical models are limited. Force simulation studies can simplify analysis by focusing on mechanical interactions while disregarding factors such as bacterial deformation and complex biochemical signals. To simulate these interactions, Atomic Force Microscopy (AFM) was employed to generate force curves, allowing precise monitoring of
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2

Le, Huong, Hoang-Nghi Mai-Thi, Xuan Le, Ngoc Quyen Tran, Cam Tu Tran, and Khon Huynh. "The concentration-independence cellular effects of fibronectin adsorbed on material surfaces with different hydrophobicities." Vietnam Journal of Biotechnology 20, no. 3 (2022): 435–44. http://dx.doi.org/10.15625/1811-4989/16585.

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In tissue engineering, coating biomaterial’s surface with extracellular matrix (ECM) proteins can promote many biological activities, including cellular responses, wound healing, and rejection reduction. Several interactions occur upon binding proteins onto the surfaces, leading to changes in the protein structural conformation, directly affecting the cell-host interactions. Therefore, this study investigates the impacts of surfaces’ wettability on protein conformation. In order to get the insights, organosilicate (OGS) was utilized to modify the tissue culture plate, resulting in surfaces wit
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3

Noh, In Sup, and Elazer R. Edelman. "Smooth Muscle Cell Ingrowth of a Surface-Modified ePTFE Vascular Graft." Key Engineering Materials 288-289 (June 2005): 367–72. http://dx.doi.org/10.4028/www.scientific.net/kem.288-289.367.

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A variety of attempts have been made to improve small diameter expanded polytetrafluoroethylene (ePTFE) vascular grafts through cellular and tissue engineering. Some of these techniques have made their way into clinical trials. Coating of endothelial cells via surface modifications has increased graft patency in some hands but lack of firm adhesion of the seeded cells on the graft surface can lead to graft failures. We increased cell-graft and graft-tissue interactions by inducing smooth muscle cell growth into the pores of the graft wall through chemical modification of superficial surfaces,
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Matsuoka, Satoshi, Hideaki Yukawa, Masayuki Inui, and Roy H. Doi. "Synergistic Interaction of Clostridium cellulovorans Cellulosomal Cellulases and HbpA." Journal of Bacteriology 189, no. 20 (2007): 7190–94. http://dx.doi.org/10.1128/jb.00842-07.

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ABSTRACT Clostridium cellulovorans, an anaerobic bacterium, produces a small nonenzymatic protein called HbpA, which has a surface layer homology domain and a type I cohesin domain similar to those found in the cellulosomal scaffolding protein CbpA. In this study, we demonstrated that HbpA could bind to cell wall fragments from C. cellulovorans and insoluble polysaccharides and form a complex with cellulosomal cellulases endoglucanase B (EngB) and endoglucanase L (EngL). Synergistic degradative action of the cellulosomal cellulase and HbpA complexes was demonstrated on acid-swollen cellulose,
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Vilaró, Pilar, Carina Sampl, Gundula Teichert, et al. "Interactions and Dissociation Constants of Galactomannan Rendered Cellulose Films with Concavalin A by SPR Spectroscopy." Polymers 12, no. 12 (2020): 3040. http://dx.doi.org/10.3390/polym12123040.

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Interactions of biomolecules at interfaces are important for a variety of physiological processes. Among these, interactions of lectins with monosaccharides have been investigated extensively in the past, while polysaccharide-lectin interactions have scarcely been investigated. Here, we explore the adsorption of galactomannans (GM) extracted from Prosopis affinis on cellulose thin films determined by a combination of multi-parameter surface plasmon resonance spectroscopy (MP-SPR) and atomic force microscopy (AFM). The galactomannan adsorbs spontaneously on the cellulose surfaces forming monola
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Munro, Thomas, Catherine M. Miller, Elsa Antunes, and Dileep Sharma. "Interactions of Osteoprogenitor Cells with a Novel Zirconia Implant Surface." Journal of Functional Biomaterials 11, no. 3 (2020): 50. http://dx.doi.org/10.3390/jfb11030050.

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Background: This study compared the in vitro response of a mouse pre-osteoblast cell line on a novel sandblasted zirconia surface with that of titanium. Material and Methods: The MC3T3-E1 subclone 4 osteoblast precursor cell line was cultured on either sandblasted titanium (SBCpTi) or sandblasted zirconia (SBY-TZP). The surface topography was analysed by three-dimensional laser microscopy and scanning electron microscope. The wettability of the discs was also assessed. The cellular response was quantified by assessing the morphology (day 1), proliferation (day 1, 3, 5, 7, 9), viability (day 1,
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7

Kunrath, Marcel F., André Correia, Eduardo R. Teixeira, Roberto Hubler, and Christer Dahlin. "Superhydrophilic Nanotextured Surfaces for Dental Implants: Influence of Early Saliva Contamination and Wet Storage." Nanomaterials 12, no. 15 (2022): 2603. http://dx.doi.org/10.3390/nano12152603.

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Hydrophilic and nanotextured surfaces for dental implants have been reported as relevant properties for early osseointegration. However, these surface characteristics are quite sensitive to oral interactions. Therefore, this pilot study aimed to investigate the superficial alterations caused on hydrophilic nanotubular surfaces after early human saliva interaction. Titanium disks were treated using an anodization protocol followed by reactive plasma application in order to achieve nanotopography and hydrophilicity, additionally; surfaces were stored in normal atmospheric oxygen or wet condition
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8

Bucior, Iwona, Simon Scheuring, Andreas Engel, and Max M. Burger. "Carbohydrate–carbohydrate interaction provides adhesion force and specificity for cellular recognition." Journal of Cell Biology 165, no. 4 (2004): 529–37. http://dx.doi.org/10.1083/jcb.200309005.

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The adhesion force and specificity in the first experimental evidence for cell–cell recognition in the animal kingdom were assigned to marine sponge cell surface proteoglycans. However, the question whether the specificity resided in a protein or carbohydrate moiety could not yet be resolved. Here, the strength and species specificity of cell–cell recognition could be assigned to a direct carbohydrate–carbohydrate interaction. Atomic force microscopy measurements revealed equally strong adhesion forces between glycan molecules (190–310 piconewtons) as between proteins in antibody–antigen inter
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9

Meyle, J., H. Wolburg, and A. F. Von Recum. "Surface Micromorphology and Cellular Interactions." Journal of Biomaterials Applications 7, no. 4 (1993): 362–74. http://dx.doi.org/10.1177/088532829300700404.

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10

Banci, Lucia, Ivano Bertini, Vito Calderone, et al. "Copper(I)-mediated protein–protein interactions result from suboptimal interaction surfaces." Biochemical Journal 422, no. 1 (2009): 37–42. http://dx.doi.org/10.1042/bj20090422.

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The homoeostasis of metal ions in cells is the result of the contribution of several cellular pathways that involve transient, often weak, protein–protein interactions. Metal transfer typically implies the formation of adducts where the metal itself acts as a bridge between proteins, by co-ordinating residues of both interacting partners. In the present study we address the interaction between the human copper(I)-chaperone HAH1 (human ATX1 homologue) and a metal-binding domain in one of its partners, namely the P-type copper-transporting ATPase, ATP7A (ATPase, Cu+ transporting, α polypeptide).
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11

De Wever, Pieter, Rodrigo de Oliveira-Silva, João Marreiros, Rob Ameloot, Dimitrios Sakellariou, and Pedro Fardim. "Topochemical Engineering of Cellulose—Carboxymethyl Cellulose Beads: A Low-Field NMR Relaxometry Study." Molecules 26, no. 1 (2020): 14. http://dx.doi.org/10.3390/molecules26010014.

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The demand for more ecological, highly engineered hydrogel beads is driven by a multitude of applications such as enzyme immobilization, tissue engineering and superabsorbent materials. Despite great interest in hydrogel fabrication and utilization, the interaction of hydrogels with water is not fully understood. In this work, NMR relaxometry experiments were performed to study bead–water interactions, by probing the changes in bead morphology and surface energy resulting from the incorporation of carboxymethyl cellulose (CMC) into a cellulose matrix. The results show that CMC improves the swe
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12

Yui, Nobuhiko. "Supramolecular Surfaces Modulating Cellular Response." Advances in Science and Technology 76 (October 2010): 10–15. http://dx.doi.org/10.4028/www.scientific.net/ast.76.10.

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Polyrotaxane-immobilized surfaces were prepared as a platform of dynamic surfaces, which can prevent from non-specific interaction with plasma proteins and platelet, and then modulate cellular functions via specific interaction with receptor protein-ligand binding through movable polyrotaxane backbone. The immobilization of the polyrotaxane was carried out via two-step protocol, in which the polyrotaxane with tetraethyleneglycol dodecanethiol (TEGDT) anchoring group at both terminals was fixed onto Au substrate via Au-S bond, followed by the fixation of TEGDT molecule onto the Au substrate to
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13

Kobayashi, Jun, Masanori Nishi, Yoshikatsu Akiyama, Masayuki Yamato, Hirofumi Yajima, and Teruo Okano. "Selective Cell Adhesion and Detachment on Antibody-Immobilized Thermoresponsive Surfaces by Temperature Changes." Journal of Robotics and Mechatronics 25, no. 4 (2013): 637–43. http://dx.doi.org/10.20965/jrm.2013.p0637.

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Anti-CD90 antibody-immobilized thermoresponsive (AIT) surfaces were prepared for obtaining temperature-triggered switching of the selective adhesion and detachment of CD90-expressed cells. Thymic carcinoma cells (Ty-82) expressing CD90 molecules on the cellular surface were unable to adhere to isotype AIT surfaces and aggregated. In contrast, Ty-82 cells selectively adhered to anti-CD90 AIT surfaces at 37°C. These results indicate that Ty-82 cells adhered to CD90 antibody-immobilized surfaces through affinity interaction, not through nonspecific interactions when grafted thermoresponsive polym
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14

Hazan, Roshasnorlyza, Srimala Sreekantan, Adilah Abdul Khalil, Ira Maya Sophia Nordin, and Ishak Mat. "TiO2 Foam: Characterization and Cell Adhesion." Advanced Materials Research 264-265 (June 2011): 1506–13. http://dx.doi.org/10.4028/www.scientific.net/amr.264-265.1506.

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In recent years, it has been proposed that the new era of implants design should be focused on the use of the new generation of biocompatible materials or reengineers the currently available materials. The objective of this research was to study cell-metal interactions using highly porous TiO2 foam. To obtain the porous TiO2 foam, polymeric foam replication methods might be one of the most effective methods. Surface chemical composition, morphology and phase are investigated by field emission scanning electron microscope (FESEM) and X-Ray Diffraction (XRD). In vitro cellular response of cells
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15

Yasuda, Takeshi, Tsumuko Okuno, Kaori Tsuji, and Hirotsugu Yasuda. "Surface-Configuration Change of CF4Plasma Treated Cellulose and Cellulose Acetate by Interaction of Water with Surfaces." Langmuir 12, no. 5 (1996): 1391–94. http://dx.doi.org/10.1021/la9501546.

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16

Sulman, Aleksanrina, Olga Grebennikova, Boris Tikhonov, Vladimir Molchanov, and Valentina Matveeva. "Immobilized cellulase: Interactions between cellulase and nanostructured supports." BIO Web of Conferences 64 (2023): 01016. http://dx.doi.org/10.1051/bioconf/20236401016.

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In this review, we will analyze the main aspects of immobilization of cellulase - an enzyme for processing cellulosic biomass waste - on nanostructured supports. Such substrates provide a large surface area, increased enzymatic load and a favorable environment for increasing the efficiency of cellulase and its stability, which leads to the creation of nanobiocatalysts for the production of biofuels and chemicals with added value. Here we will discuss nanostructured supports, methods of cellulase immobilization, the interaction between the enzyme and the support, as well as factors affecting th
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17

Carambassis, Archie, and Mark W. Rutland. "Interactions of Cellulose Surfaces: Effect of Electrolyte." Langmuir 15, no. 17 (1999): 5584–90. http://dx.doi.org/10.1021/la9815852.

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18

Bachhuka, Akash. "(Invited) nanoengineered Surfaces for Modulating Cell-Surface Interaction and Sensing Applications." ECS Meeting Abstracts MA2023-01, no. 34 (2023): 1889. http://dx.doi.org/10.1149/ma2023-01341889mtgabs.

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The greatest challenge in the field of biomaterials is the understanding and prediction of long-term biological responses in patients receiving implantable materials. Reconstructing and detailing these mechanisms may allow for more targeted approaches and highlights how immune processes are amenable to manipulation by synthetic biomaterials. Surface nanotopography and chemistry are critical factors in integrating implanted devices into tissues and in the satisfactory resolution of the wound healing process. However, how the interplay between surface chemistry and nanotopography may influence i
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19

Gozan, Misri, Andre Fahriz Harahap, Chandra Paska Bakti, and Siswa Setyahadi. "Optimization of cellulase production by bacillus sp. BPPT CC RK2 with pH and temperature variation using response surface methodology." E3S Web of Conferences 67 (2018): 02051. http://dx.doi.org/10.1051/e3sconf/20186702051.

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Indonesia has abundant ethanol biomass feedstocks. However the second-generation ethanol production process is still hampered by the unavailability of cellulase enzyme in the process of decomposition of lignocellulose into saccharides that can be processed into ethanol through fermentation. Cellulase is known as exozyme produced by Bacillus sp. in submerged fermentation. In this study, cellulase production by Bacillus sp. CC BPPT RK2 on natural and abundant agricultural waste substrates (rice bran and coconut water) was evaluated by investigating the optimum conditions for cellulase production
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20

Suárez-Franco, José Luis, Manuel García-Hipólito, Miguel Ángel Surárez-Rosales, et al. "Effects of Surface Morphology ofZnAl2O4Ceramic Materials on Osteoblastic Cells Responses." Journal of Nanomaterials 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/361249.

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Ceramic scaffolds are widely studied in the tissue engineering field due to their potential in medical applications as bone substitutes or as bone-filling materials. The purpose of this study was to investigate the effect of surface morphology of nanostructure thin films of ZnAl2O4prepared by spray pyrolysis and bulk pellets of polycrystalline ZnAl2O4prepared by chemical coprecipitation reaction on thein vitrocell adhesion, viability, and cell-material interactions of osteoblastic cells. Our result showed that cell attachment was significantly enhanced from 60 to 80% on the ZnAl2O4nanostructur
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21

Stahelin, Robert V. "Surface plasmon resonance: a useful technique for cell biologists to characterize biomolecular interactions." Molecular Biology of the Cell 24, no. 7 (2013): 883–86. http://dx.doi.org/10.1091/mbc.e12-10-0713.

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Surface plasmon resonance (SPR) is a powerful technique for monitoring the affinity and selectivity of biomolecular interactions. SPR allows for analysis of association and dissociation rate constants and modeling of biomolecular interaction kinetics, as well as for equilibrium binding analysis and ligand specificity studies. SPR has received much use and improved precision in classifying protein–protein interactions, as well as in studying small-molecule ligand binding to receptors; however, lipid–protein interactions have been underserved in this regard. With the field of lipids perhaps the
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Hedberg-Dirk, Elizabeth L., and Ulises A. Martinez. "Large-Scale Protein Arrays Generated with Interferometric Lithography for Spatial Control of Cell-Material Interactions." Journal of Nanomaterials 2010 (2010): 1–9. http://dx.doi.org/10.1155/2010/176750.

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Understanding cellular interactions with material surfaces at the micro- and nanometer scale is essential for the development of the next generation of biomaterials. Several techniques have been used to create micro- and nanopatterned surfaces as a means of studying cellular interactions with a surface. Herein, we report the novel use of interference lithography to create a large (4 ) array of 33 nm deep channels in a gold surface, to expose an antireflective coating on a silicon wafer at the bottom of the gold channels. The fabricated pores had a diameter of 140–350 nm separated by an average
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El-Karni, El hassan, Zakaria Jalil, Mohamed Amine Kasbaji та ін. "Theoretical and computational study of tannin adsorption on wood surface particularly on ꞵ-cellulose". Current Chemistry Letters 14, № 3 (2025): 667–80. https://doi.org/10.5267/j.ccl.2025.1.005.

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This theoretical study investigates the adsorption of eco-friendly tannins on cellulose surfaces as a means to develop sustainable wood adhesives with reduced formaldehyde emissions. Conceptual density functional theory calculations reveal the global and local chemical reactivity parameters governing the interaction between tannins and wood substrates. Monte Carlo simulations explore the configuration space of substrate adsorbate, while molecular dynamics simulations elucidate the binding strength and stability of tannins. The results demonstrate that tannins adsorb parallel to the cellulose s
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He, Yongning, Steffen Mueller, Paul R. Chipman, et al. "Complexes of Poliovirus Serotypes with Their Common Cellular Receptor, CD155." Journal of Virology 77, no. 8 (2003): 4827–35. http://dx.doi.org/10.1128/jvi.77.8.4827-4835.2003.

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ABSTRACT Structures of all three poliovirus (PV) serotypes (PV1, PV2, and PV3) complexed with their cellular receptor, PV receptor (PVR or CD155), were determined by cryoelectron microscopy. Both glycosylated and fully deglycosylated CD155 exhibited similar binding sites and orientations in the viral canyon for all three PV serotypes, showing that all three serotypes use a common mechanism for cell entry. Difference maps between the glycosylated and deglycosylated CD155 complexes determined the sites of the carbohydrate moieties that, in turn, helped to verify the position of the receptor rela
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Negrescu, Andreea Mariana, Simona Nistorescu, Anca Florina Bonciu, et al. "Macrophage Immunomodulation and Suppression of Bacterial Growth by Polydimethylsiloxane Surface-Interrupted Microlines’ Topography Targeting Breast Implant Applications." Polymers 16, no. 21 (2024): 3046. http://dx.doi.org/10.3390/polym16213046.

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Since breast cancer is one of the most common forms of cancer in women, silicone mammary implants have been extensively employed in numerous breast reconstruction procedures. However, despite the crucial role they play, their interaction with the host’s immune system and microbiome is poorly understood. Considering this, the present work investigates the immunomodulatory and bacterial mitigation potential of six textured surfaces, based on linear step-like features with various regular and irregular multiscaled arrangements, in comparison to a flat PDMS surface. We hypothesise that the chosen
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Niegelhell, Katrin, Thomas Ganner, Harald Plank, Evelyn Jantscher-Krenn, and Stefan Spirk. "Lectins at Interfaces—An Atomic Force Microscopy and Multi-Parameter-Surface Plasmon Resonance Study." Materials 11, no. 12 (2018): 2348. http://dx.doi.org/10.3390/ma11122348.

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Lectins are a diverse class of carbohydrate binding proteins with pivotal roles in cell communication and signaling in many (patho)physiologic processes in the human body, making them promising targets in drug development, for instance, in cancer or infectious diseases. Other applications of lectins employ their ability to recognize specific glycan epitopes in biosensors and glycan microarrays. While a lot of research has focused on lectin interaction with specific carbohydrates, the interaction potential of lectins with different types of surfaces has not been addressed extensively. Here, we
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27

Masas, Daria S., Maria S. Ivanova, Gocha Sh Gogelashvili, Alexander S. Maslennikov, Yury B. Grunin, and Tatiana Yu Grunina. "Analysis of water state adsorbed by cellulose fibers." Butlerov Communications 58, no. 5 (2019): 24–31. http://dx.doi.org/10.37952/roi-jbc-01/19-58-5-24.

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Modernized model of microfibril cellulose layered structure is proposed. This model considers presence of slit-shaped micropores in space between elementary fibrils and cellulose microfibrils. It’s discussed the nature of donor-acceptor hydrogen bonds formation: intra-, intermolecular, and interlayer bonds inherent in each glucopyranous cellulose link. It’s described the mechanism of water molecules specific adsorption interactions in a monolayer with active centers located on the hydrophilic surfaces of elementary fibrils. Dipole-dipole energy transition into energy of hydrogen bond is discus
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Braniste, Tudor, Ion Tiginyanu, Tibor Horvath, et al. "Viability and proliferation of endothelial cells upon exposure to GaN nanoparticles." Beilstein Journal of Nanotechnology 7 (September 23, 2016): 1330–37. http://dx.doi.org/10.3762/bjnano.7.124.

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Nanotechnology is a rapidly growing and promising field of interest in medicine; however, nanoparticle–cell interactions are not yet fully understood. The goal of this work was to examine the interaction between endothelial cells and gallium nitride (GaN) semiconductor nanoparticles. Cellular viability, adhesion, proliferation, and uptake of nanoparticles by endothelial cells were investigated. The effect of free GaN nanoparticles versus the effect of growing endothelial cells on GaN functionalized surfaces was examined. To functionalize surfaces with GaN, GaN nanoparticles were synthesized on
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29

Juárez-Maldonado, Antonio, Hortensia Ortega-Ortíz, América Berenice Morales-Díaz, et al. "Nanoparticles and Nanomaterials as Plant Biostimulants." International Journal of Molecular Sciences 20, no. 1 (2019): 162. http://dx.doi.org/10.3390/ijms20010162.

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Biostimulants are materials that when applied in small amounts are capable of promoting plant growth. Nanoparticles (NPs) and nanomaterials (NMs) can be considered as biostimulants since, in specific ranges of concentration, generally in small levels, they increase plant growth. Pristine NPs and NMs have a high density of surface charges capable of unspecific interactions with the surface charges of the cell walls and membranes of plant cells. In the same way, functionalized NPs and NMs, and the NPs and NMs with a corona formed after the exposition to natural fluids such as water, soil solutio
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Österbeg, Monika, and Per M. Claesson. "Interactions between cellulose surfaces: effect of solution pH." Journal of Adhesion Science and Technology 14, no. 5 (2000): 603–18. http://dx.doi.org/10.1163/156856100742771.

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Lydon, M. J., T. W. Minett, and B. J. Tighe. "Cellular interactions with synthetic polymer surfaces in culture." Biomaterials 6, no. 6 (1985): 396–402. http://dx.doi.org/10.1016/0142-9612(85)90100-0.

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Salmi, Jani, Tiina Nypelö, Monika Österberg, and Janne Laine. "Layer structures formed by silica nanoparticles and cellulose nanofibrils with cationic polyacrylamide (C-PAM) on cellulose surface and their influence on interactions." BioResources 4, no. 2 (2009): 602–25. http://dx.doi.org/10.15376/biores.4.2.602-625.

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A quartz crystal microbalance with dissipation monitoring (QCM-D) was used to study the adsorption of the layer formed by silica nanoparticles (SNP) and cellulose nanofibrils (NFC) together with cationic polyacrylamide (C-PAM) on cellulose surface, accompanied by use of atomic force microscope (AFM) to study the interactions between cellulose surfaces. The purpose was to understand the multilayer build-up compared to complex structure adsorption. The layer thickness and consequently also the repulsion between surfaces increased with each addition step during layer formation in the SNP-C-PAM sy
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Myllytie, Petri, Jani Salmi, and Janne Laine. "The influence of pH on the adsorption and interaction of chitosan with cellulose." BioResources 4, no. 4 (2009): 1647–62. http://dx.doi.org/10.15376/biores.4.4.1647-1662.

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The pH dependent adsorption behavior of chitosan onto a cellulose model surface was studied by quartz crystal microbalance with dissipation (QCM-D). The molecular level interactions between adsorbed chitosan layers were studied by atom force microscopy (AFM) colloidal probe force measurements in the liquid phase. Adsorption of chitosan increased with pH below the solubility limit of the polymer. The adsorption behavior could not be accounted for solely on the basis of electrostatic interactions; thus a specific interaction between the polymers existed. Swelling and viscoelastic properties of t
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Oikonomou, Evdokia K., and Jean-François Berret. "Adsorption of Fragrance Capsules onto Cellulose Nano- and Micro-Cellulose Fibers in Presence of Guar Biopolymers." Coatings 13, no. 11 (2023): 1831. http://dx.doi.org/10.3390/coatings13111831.

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Fabric softeners are formulated to enhance textile softness and impart a pleasant scent. One of the most efficient technologies for controlled fragrance delivery onto fabrics involves encapsulating scent molecules in polymer capsules. Here, we investigate the adsorption of anionic fragrance capsules on cotton fabrics with the goal of reducing the reliance on palm-oil-derived surfactants. First, we employ 200 nm cellulose nanocrystals (CNC) as a reliable model for cotton fibers. CNC enables us to explore interactions among various softener components, including surfactants, guar biopolymers, an
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Fang, Qingming, Joel Andrews, Nidhi Sharma та ін. "Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress". Nucleic Acids Research 47, № 12 (2019): 6269–86. http://dx.doi.org/10.1093/nar/gkz293.

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Abstract Protein–protein interactions regulate many essential enzymatic processes in the cell. Somatic mutations outside of an enzyme active site can therefore impact cellular function by disruption of critical protein–protein interactions. In our investigation of the cellular impact of the T304I cancer mutation of DNA Polymerase β (Polβ), we find that mutation of this surface threonine residue impacts critical Polβ protein–protein interactions. We show that proteasome-mediated degradation of Polβ is regulated by both ubiquitin-dependent and ubiquitin-independent processes via unique protein–p
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36

Custódio, Catarina A., and João F. Mano. "Cell Surface Engineering to Control Cellular Interactions." ChemNanoMat 2, no. 5 (2016): 376–84. http://dx.doi.org/10.1002/cnma.201600047.

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37

Canullo, Luigi, Tullio Genova, Esperanza Gross Trujillo, et al. "Fibroblast Interaction with Different Abutment Surfaces: In Vitro Study." International Journal of Molecular Sciences 21, no. 6 (2020): 1919. http://dx.doi.org/10.3390/ijms21061919.

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Background: Attaining an effective mucosal attachment to the transmucosal part of the implant could protect the peri-implant bone. Aim: To evaluate if chair side surface treatments (plasma of Argon and ultraviolet light) may affect fibroblast adhesion on different titanium surfaces designed for soft tissue healing. Methods: Grade 5 titanium discs with four different surface topographies were subdivided into 3 groups: argon-plasma; ultraviolet light, and no treatment. Cell morphology and adhesion tests were performed at 20 min, 24 h, and 72 h. Results: Qualitative observation of the surfaces pe
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Lucenius, Jessica, Juan José Valle-Delgado, Kirsti Parikka, and Monika Österberg. "Understanding hemicellulose-cellulose interactions in cellulose nanofibril-based composites." Journal of Colloid and Interface Science 555 (November 2019): 104–14. http://dx.doi.org/10.1016/j.jcis.2019.07.053.

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39

Preissner, K. T. "Heparinoids and cellular interactions in the vascular system." Hämostaseologie 16, no. 01 (1996): 28–34. http://dx.doi.org/10.1055/s-0038-1656635.

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SummaryHeparin and related polysaccharides have long been used for therapautic intervention in different disease states related to thromboembolic complications. The localization and functional availability of heparin-like components in the body is mostly confined to cell surfaces and extracellular matrix/basement membranes. Their strategic position particularly in the vascular system enables heparinoids linked to various core proteins (designated as heparan sulfate proteoglycans) to interact with a variety of heparin-binding proteins such as apolipoproteins, lipases, proteases and protease inh
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Guttmann, Robin, Johannes Hoja, Christoph Lechner, Reinhard J. Maurer, and Alexander F. Sax. "Adhesion, forces and the stability of interfaces." Beilstein Journal of Organic Chemistry 15 (January 11, 2019): 106–29. http://dx.doi.org/10.3762/bjoc.15.12.

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Weak molecular interactions (WMI) are responsible for processes such as physisorption; they are essential for the structure and stability of interfaces, and for bulk properties of liquids and molecular crystals. The dispersion interaction is one of the four basic interactions types – electrostatics, induction, dispersion and exchange repulsion – of which all WMIs are composed. The fact that each class of basic interactions covers a wide range explains the large variety of WMIs. To some of them, special names are assigned, such as hydrogen bonding or hydrophobic interactions. In chemistry, thes
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Mudedla, Sathish Kumar, Maisa Vuorte, Elias Veijola, et al. "Effect of oxidation on cellulose and water structure: a molecular dynamics simulation study." Cellulose 28, no. 7 (2021): 3917–33. http://dx.doi.org/10.1007/s10570-021-03751-8.

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AbstractEnzymatic cleavage of glycocidic bonds is an important, green and biocompatible means to refine lignocellulosic biomass. Here, the effect of the resulting oxidation point defects on the structural and water interactions of crystalline cellulose {100} surface are explored using classical molecular dynamics simulations. We show that even single oxidations reduce the connections within cellulose crystal significantly, mostly via local interactions between the chains along the surface plane but also via the oxidation defects changing the structure of the crystal in direction perpendicular
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Kumari, Pallavi, Tali Sayas, Patricia Bucki, Sigal Brown-Miyara, and Maya Kleiman. "Real-Time Visualization of Cellulase Activity by Microorganisms on Surface." International Journal of Molecular Sciences 21, no. 18 (2020): 6593. http://dx.doi.org/10.3390/ijms21186593.

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A variety of methods to detect cellulase secretion by microorganisms has been developed over the years, none of which enables the real-time visualization of cellulase activity on a surface. This visualization is critical to study the interaction between soil-borne cellulase-secreting microorganisms and the surface of plant roots and specifically, the effect of surface features on this interaction. Here, we modified the known carboxymethyl cellulase (CMC) hydrolysis visualization method to enable the real-time tracking of cellulase activity of microorganisms on a surface. A surface was formed u
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Moon, Jooa, Guanghao Hu, and Tomohiro Hayashi. "Application of Machine Learning in the Quantitative Analysis of the Surface Characteristics of Highly Abundant Cytoplasmic Proteins: Toward AI-Based Biomimetics." Biomimetics 9, no. 3 (2024): 162. http://dx.doi.org/10.3390/biomimetics9030162.

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Proteins in the crowded environment of human cells have often been studied regarding nonspecific interactions, misfolding, and aggregation, which may cause cellular malfunction and disease. Specifically, proteins with high abundance are more susceptible to these issues due to the law of mass action. Therefore, the surfaces of highly abundant cytoplasmic (HAC) proteins directly exposed to the environment can exhibit specific physicochemical, structural, and geometrical characteristics that reduce nonspecific interactions and adapt to the environment. However, the quantitative relationships betw
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Bryszewska, Malgorzata Anita, Daniel Gutierez Pareja, Lukasz Kaczmarek, Anna Sobczyk-Guzenda, Malgorzata Piotrowska, and Damian Batory. "SCOBY Cellulose-Based Materials Hydrophobized Using Stearic Acid and Apple Powder." International Journal of Molecular Sciences 25, no. 24 (2024): 13746. https://doi.org/10.3390/ijms252413746.

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Bacterial cellulose (BC) is a subject of interest for researchers due to its advantageous characteristics, including a straightforward manufacturing process, biocompatibility, and extensive modification potential. The hydrophilic nature of the material is beneficial in some applications, yet a limiting factor in others. This study aimed to develop BC-based materials with goFogureod moisture resistance. The modification of bacterial cellulose (BC) using apple powder, stearic acid, or a combination of these modifiers resulted in the formation of a range of materials, some of which had their surf
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Aguirre, Luis E., Alexandre de Oliveira, David Seč, et al. "Sensing surface morphology of biofibers by decorating spider silk and cellulosic filaments with nematic microdroplets." Proceedings of the National Academy of Sciences 113, no. 5 (2016): 1174–79. http://dx.doi.org/10.1073/pnas.1518739113.

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Probing the surface morphology of microthin fibers such as naturally occurring biofibers is essential for understanding their structural properties, biological function, and mechanical performance. The state-of-the-art methods for studying the surfaces of biofibers are atomic force microscopy imaging and scanning electron microscopy, which well characterize surface geometry of the fibers but provide little information on the local interaction potential of the fibers with the surrounding material. In contrast, complex nematic fluids respond very well to external fields and change their optical
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Schwaminger, Sebastian P., Paula Fraga-García, Felix Selbach, et al. "Bio-nano interactions: cellulase on iron oxide nanoparticle surfaces." Adsorption 23, no. 2-3 (2016): 281–92. http://dx.doi.org/10.1007/s10450-016-9849-y.

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Wen, Fei, Jie Sun, and Huimin Zhao. "Yeast Surface Display of Trifunctional Minicellulosomes for Simultaneous Saccharification and Fermentation of Cellulose to Ethanol." Applied and Environmental Microbiology 76, no. 4 (2009): 1251–60. http://dx.doi.org/10.1128/aem.01687-09.

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ABSTRACT By combining cellulase production, cellulose hydrolysis, and sugar fermentation into a single step, consolidated bioprocessing (CBP) represents a promising technology for biofuel production. Here we report engineering of Saccharomyces cerevisiae strains displaying a series of uni-, bi-, and trifunctional minicellulosomes. These minicellulosomes consist of (i) a miniscaffoldin containing a cellulose-binding domain and three cohesin modules, which was tethered to the cell surface through the yeast a-agglutinin adhesion receptor, and (ii) up to three types of cellulases, an endoglucanase
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Wang, Yi, Sok Ho Kim, Ramya Natarajan, et al. "Spermidine Inversely Influences Surface Interactions and Planktonic Growth in Agrobacterium tumefaciens." Journal of Bacteriology 198, no. 19 (2016): 2682–91. http://dx.doi.org/10.1128/jb.00265-16.

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ABSTRACTIn bacteria, the functions of polyamines, small linear polycations, are poorly defined, but these metabolites can influence biofilm formation in several systems. Transposon insertions in an ornithine decarboxylase (odc) gene inAgrobacterium tumefaciens, predicted to direct synthesis of the polyamine putrescine from ornithine, resulted in elevated cellulose. Null mutants forodcgrew somewhat slowly in a polyamine-free medium but exhibited increased biofilm formation that was dependent on cellulose production. Spermidine is an essential metabolite inA. tumefaciensand is synthesized from p
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Kostylev, Maxim, and David Wilson. "A Distinct Model of Synergism between a Processive Endocellulase (TfCel9A) and an Exocellulase (TfCel48A) from Thermobifida fusca." Applied and Environmental Microbiology 80, no. 1 (2013): 339–44. http://dx.doi.org/10.1128/aem.02706-13.

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ABSTRACTLignocellulosic biomass is digested in nature by the synergistic activities of enzymes with complementary properties, and understanding synergistic interactions will improve the efficiency of industrial biomass use for sustainable fuels and chemicals. Cel9A and Cel48A from a model bacterium,Thermobifida fusca(TfCel9A and TfCel48A, respectively), are two cellulases with different properties and have previously been shown to synergize well with each other. TfCel9A is a processive endocellulase with relatively high activity on crystalline cellulose. TfCel48A is a reducing end-directed exo
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Bimbo, Luis M., Mirkka Sarparanta, Ermei Mäkilä, et al. "Cellular interactions of surface modified nanoporous silicon particles." Nanoscale 4, no. 10 (2012): 3184. http://dx.doi.org/10.1039/c2nr30397c.

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