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Relevant bibliographies by topics / Interazioni proteina

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Journal articles
Dissertations / Theses

Academic literature on the topic 'Interazioni proteina'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

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Journal articles on the topic "Interazioni proteina"

1

Di Stefano, Danilo. "Proteine morfogenetiche, cellule staminali e loro interazioni nella rigenerazione ossea." Italian Oral Surgery 8, no. 5 (2009): 243–46. http://dx.doi.org/10.1016/j.ios.2009.08.001.

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Dissertations / Theses on the topic "Interazioni proteina"

1

INCANI, FEDERICA. "Definizione del ruolo della proteina AIRE attraverso la ricerca di proteine interagenti." Doctoral thesis, Università degli Studi di Cagliari, 2011. http://hdl.handle.net/11584/266270.

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2

Cozza, Giorgio. "Strategie computazionali per lo studio delle interazioni tra macromolecole e per la ricerca di nuovi inibitori di proteine chinasi." Doctoral thesis, Università degli studi di Padova, 2008. http://hdl.handle.net/11577/3425569.

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The concept of "druggable genome" limits the molecular targets for which commercially viable compounds can be developed. In humans, whose genome accounts for about 30,000 genes, it has been calculated that a subset of no more than 3,000 genes express proteins able to bind drug-like molecules. This limit derives from the fact that the ability of a protein to bind a small molecule with the appropriate chemical properties does not necessarily make it a potential drug target, this latter feature being only applied to proteins that are also linked to disease. Among these, it has become evident that

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3

STANCANELLI, EDUARDO. "UTILIZZO DELLA SPETTROSCOPIA DI RISONANZA MAGNETICA NUCLEARE PER STUDIARE INTERAZIONI LIGANDO PROTEINA DI DERIVATI OLIGOSACCARIDICI DELL'EPARAN SOLFATO, OTTENUTI MEDIANTE SINTESI CHEMIOENZIMATICA." Doctoral thesis, Università degli studi di Pavia, 2020. http://hdl.handle.net/11571/1321849.

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Leparan solfato è un polisaccaride lineare altamente solfatato appartenente alla famiglia dei glicosamminoglicani. Esso è ubiquitariamente presente in tutte le cellule dei mammiferi e gioca un ruolo importanti in una serie di processi fisiologici e patologici come sviluppo embrionale, infezioni batteriche e virali, risposta infiammatoria e coagulazione del sangue Leparan solfato è composto da ununità disaccaridica di acido glucuronico o iduronico legato ad unammina che può essere solfata o acetilata. La disposizione dei gruppi solfato e la posizione dellacido iduronico sulle catene di eparan s

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4

Frasson, Ilaria. "Nuove strategie antimicrobiche contro rilevanti patogeni umani." Doctoral thesis, Università degli studi di Padova, 2010. http://hdl.handle.net/11577/3426592.

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Despite a century of often successful prevention and treatment efforts, infectious diseases remain an important global problem in public health, causing over 13 million deaths each year. This work has been developed on two areas of major concern nowadays: HIV-1 infection and emerging antimicrobial resistance. The first part of this thesis focused on the definition of the biological role of the dimerization of Nef, HIV-1 accessory protein. This function has been reported to take place in vivo, neveretheless it hasn’t been well characterized yet. We believe that the inihibition of Nef oligomeri

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5

CALLEA, LARA. "MODELING OF LIGAND-PROTEIN BINDING WITH ADVANCED MOLECULAR DYNAMICS METHODS." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2022. http://hdl.handle.net/10281/374733.

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Questa tesi è incentrata sulla modellazione del binding ligando-proteina con metodi computazionali basati sulla dinamica molecolare. La comprensione di questo processo è fondamentale per la progettazione e la scoperta di nuovi farmaci e l'uso di metodi computazionali per supportare la ricerca sperimentale in questo campo è in costante crescita. Oggi, grazie alla crescente potenza dei computer, è possibile studiare l'intero processo di binding/unbinding del ligando e ottenere stime sulle proprietà termodinamiche e cinetiche. Alla luce di ciò, durante il mio dottorato, diversi metodi avanzati d

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6

Timmoneri, Martina. "Inhibition of HCMV replication by small molecules interfering with the dimerization of the DNA polymerase processivity factor UL44." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3425876.

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Human cytomegalovirus (HCMV) is a leading cause of severe disease in immunocompromised individuals, including AIDS and transplanted patients, and in congenitally infected newborns. Despite the availability of several drugs, pharmacological treatment of HCMV infections is associated with poor bioavailability, toxicity and the emergence of resistant strains. Furthermore, no vaccine is available and no drugs are approved to prevent vertical transmission during pregnancy, therefore, it is essential to identify new potential targets of therapeutic intervention. HCMV DNA polymerase accessory pro

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7

Di, Gaspero Mattia. "Proteins in White Wines: Their Interaction With Tannins And Aroma Compounds." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3425855.

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The presence of protein in white wines represents a major problem for the wine industry mainly due to the fact that proteins generate haze in the bottled white wines. Protein instability, which results in wine haze formation, is due to some grape PR-Proteins that thanks to their intrinsic resistance survive the vinification process, pass into the wine where cause the appearance of undesirable haze and deposits, leading to rejection by consumers. Protein hazing of white wines is considered to be a three-step process, involving protein denaturation followed by aggregation into colloidal particle

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8

Muratore, Giulia. "SVILUPPO DI NUOVE STRATEGIE ANTIVIRALI DIRETTE CONTRO L' RNA POLIMERASI DEL VIRUS DELL'INFLUENZA." Doctoral thesis, Università degli studi di Padova, 2011. http://hdl.handle.net/11577/3422859.

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Influenza (flu) is an airborne highly-infectious disease, characterized by high morbidity and significant mortality, especially in at-risk population (young children, elderly people, patients with cronical disease). Annually, 20% of general population is affected by seasonal epidemics sustained by genetic variants of already circulating influenza virus strains. For this reason the vaccine has to be changed every year with a considerable economic impact. Furthermore, the influenza virus is responsible for occasional pandemics affecting million of people worldwide. The migratory water bird are t

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9

Celestino, Michele. "Interazione tra proteine virali e cellulari coinvolte nelle fasi tardive del ciclo replicativo del virus dell'immunodeficienza felina." Doctoral thesis, Università degli studi di Padova, 2011. http://hdl.handle.net/11577/3427508.

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Feline Immunodeficiency Virus (FIV) is a non-primate lentivirus that causes an immunodeficiency syndrome in domestic cats, that is striking similar to AIDS in humans. FIV is similar to Human Immunodeficiency Virus type 1 (HIV-1) in many molecular and biochemical properties, thus representing an attractive model for AIDS research in many different aspects ranging from pathogenesis to therapeutic approaches. In this context, understanding the interplay between viral and host factors plays a crucial role in the efforts for elucidating the molecular mechanisms involved in virus pathogenicity and t

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10

MILANESI, RICCARDO. "Metabolism and signaling crosstalk regulates nutrients perception and mitochondrial respiration in eukaryotic model systems." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2022. http://hdl.handle.net/10281/375389.

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Tutti gli eucarioti presentano sistemi di percezione per le fonti di carbonio e azoto tramite la quale la crescita cellulare è coordinata con lo stato nutrizionale. In particolare, I metaboliti della parte alta della glicolisi influenzano lo stato di attivazione della via di PKA e di Snf1/AMPK/SnRK1 in lievito, mammifero e piante. Mentre, la via del complesso di TORC1 è al centro di un sistema di segnalazione per la disponibilità di amminoacidi. Di particolare interesse è il meccanismo di interazione tra la via di Snf1/AMPK e Ras/PKA con il metabolismo del glucosio la cui regolazione non è tut

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